Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
GRM4	2914	broad.mit.edu	37	6	34059820	34059820	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr6:34059820G>A	ENST00000538487.2	-	3	1019	c.576C>T	c.(574-576)taC>taT	p.Y192Y	GRM4_ENST00000535756.1_Silent_p.Y59Y|GRM4_ENST00000609222.1_Silent_p.Y59Y|GRM4_ENST00000374181.4_Silent_p.Y192Y|GRM4_ENST00000544773.2_Silent_p.Y23Y|GRM4_ENST00000374177.3_Silent_p.Y123Y|GRM4_ENST00000455714.2_Silent_p.Y52Y	NM_000841.2|NM_001256811.1	NP_000832.1|NP_001243740.1	Q14833	GRM4_HUMAN	glutamate receptor, metabotropic 4						activation of MAPK activity|inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway|neuroprotection|neurotransmitter secretion|positive regulation of MAPKKK cascade	cytoplasmic vesicle|integral to plasma membrane	G-protein coupled receptor activity|glutamate receptor activity			NS(1)|breast(1)|endometrium(4)|kidney(4)|large_intestine(9)|liver(1)|lung(19)|ovary(1)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	48					L-Glutamic Acid(DB00142)	AGAAGAAGTCGTAGCGGCTGT	0.637000													21	45					0	0	1	0	0
RP11-146E13.4	0	broad.mit.edu	37	14	19857036	19857036	+	RNA	SNP	A	A	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr14:19857036A>G	ENST00000548109.1	+	0	72																											CTGGATAATAAAGTTCATCTC	0.373000													5	59					0	0	1	0	0
MAST2	23139	broad.mit.edu	37	1	46295175	46295175	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:46295175G>A	ENST00000361297.2	+	3	673	c.390G>A	c.(388-390)tcG>tcA	p.S130S	MAST2_ENST00000372009.2_Silent_p.S130S	NM_015112.2	NP_055927.2	Q6P0Q8	MAST2_HUMAN	microtubule associated serine/threonine kinase 2	130					regulation of interleukin-12 biosynthetic process|spermatid differentiation	cytoplasm|cytoskeleton|plasma membrane	ATP binding|magnesium ion binding|phosphatase binding|protein serine/threonine kinase activity			breast(1)|lung(3)|ovary(5)|stomach(2)	11	Acute lymphoblastic leukemia(166;0.155)|Lung SC(450;0.184)					CTTGGCAGTCGTCAGGAGAAG	0.468000													18	42					0	0	1	0	0
KRTAP4-7	100132476	broad.mit.edu	37	17	39240560	39240560	+	Silent	SNP	T	T	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:39240560T>C	ENST00000391417.4	+	1	102	c.102T>C	c.(100-102)tgT>tgC	p.C34C		NM_033061.3	NP_149050.3			keratin associated protein 4-7									p.C34C(2)		NS(1)|endometrium(3)|kidney(1)|lung(1)|prostate(2)|urinary_tract(1)	9						AGACCACCTGTTGCAGGACCA	0.647000													3	48					0	0	1	0	0
TRPC4	7223	broad.mit.edu	37	13	38225434	38225434	+	Nonsense_Mutation	SNP	T	T	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr13:38225434T>A	ENST00000379705.3	-	8	2904	c.2047A>T	c.(2047-2049)Aga>Tga	p.R683*	TRPC4_ENST00000338947.5_Nonsense_Mutation_p.R510*|TRPC4_ENST00000379679.1_Nonsense_Mutation_p.R510*|TRPC4_ENST00000355779.2_Nonsense_Mutation_p.R683*|TRPC4_ENST00000379673.2_Intron|TRPC4_ENST00000447043.1_Nonsense_Mutation_p.R683*|TRPC4_ENST00000379681.3_Nonsense_Mutation_p.R683*|TRPC4_ENST00000358477.2_Nonsense_Mutation_p.R683*|TRPC4_ENST00000426868.2_3'UTR			Q9UBN4	TRPC4_HUMAN	transient receptor potential cation channel, subfamily C, member 4	683	Binds to ITPR1, ITPR2 and ITPR3.				axon guidance|calcium ion import	basolateral plasma membrane|calcium channel complex|cell surface|cortical cytoskeleton	beta-catenin binding|cadherin binding|store-operated calcium channel activity			NS(2)|breast(4)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(26)|lung(30)|ovary(4)|prostate(1)|skin(4)|urinary_tract(2)	83				all cancers(112;1.92e-08)|Epithelial(112;5.04e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.000677)|GBM - Glioblastoma multiforme(144;0.00623)|BRCA - Breast invasive adenocarcinoma(63;0.0126)		GGCTTTCTTCTCATCTTTTTC	0.383000													28	37					0	0	1	0	0
CLEC12A	160364	broad.mit.edu	37	12	10131592	10131592	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr12:10131592G>A	ENST00000304361.4	+	2	301	c.119G>A	c.(118-120)cGt>cAt	p.R40H	CLEC12A_ENST00000355690.4_Missense_Mutation_p.R50H|CLEC12A_ENST00000434319.2_Missense_Mutation_p.R40H|CLEC12A_ENST00000350667.4_Intron	NM_138337.5|NM_201623.3	NP_612210.4|NP_963917.2	Q5QGZ9	CL12A_HUMAN	C-type lectin domain family 12, member A	40						integral to membrane|plasma membrane	receptor activity|sugar binding			breast(1)|endometrium(1)|kidney(3)|large_intestine(2)|lung(6)|skin(2)|upper_aerodigestive_tract(1)	16						CATGTATGGCGTCCAGCAGCC	0.438000													32	61					0	0	1	0	0
TAS2R9	50835	broad.mit.edu	37	12	10962396	10962396	+	Silent	SNP	A	A	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr12:10962396A>G	ENST00000240691.2	-	1	371	c.279T>C	c.(277-279)aaT>aaC	p.N93N		NM_023917.2	NP_076406.1	Q9NYW1	TA2R9_HUMAN	taste receptor, type 2, member 9	93					sensory perception of taste	integral to membrane	taste receptor activity			endometrium(1)|kidney(1)|large_intestine(4)|lung(7)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17						GACTTGAATTATTGGCAAATG	0.383000													16	35					0	0	1	0	0
TTN	7273	broad.mit.edu	37	2	179394741	179394741	+	Missense_Mutation	SNP	T	T	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr2:179394741T>A	ENST00000589042.1	-	359	106701	c.106477A>T	c.(106477-106479)Aca>Tca	p.T35493S	TTN-AS1_ENST00000592182.1_RNA|TTN-AS1_ENST00000590040.1_RNA|TTN-AS1_ENST00000456053.1_RNA|TTN-AS1_ENST00000587568.1_RNA|TTN-AS1_ENST00000592630.1_RNA|TTN-AS1_ENST00000591466.1_RNA|TTN-AS1_ENST00000585451.1_RNA|TTN-AS1_ENST00000586707.1_RNA|TTN-AS1_ENST00000586831.1_RNA|TTN-AS1_ENST00000450692.2_RNA|TTN-AS1_ENST00000604571.1_RNA|TTN-AS1_ENST00000589391.1_RNA|TTN-AS1_ENST00000588244.1_RNA|TTN-AS1_ENST00000592836.1_RNA|TTN-AS1_ENST00000587944.1_RNA|TTN-AS1_ENST00000585358.1_RNA|TTN-AS1_ENST00000588716.1_RNA|TTN-AS1_ENST00000588804.1_RNA|TTN-AS1_ENST00000588257.1_RNA|TTN-AS1_ENST00000585487.1_RNA|TTN_ENST00000359218.5_Missense_Mutation_p.T26553S|TTN-AS1_ENST00000592600.1_RNA|TTN_ENST00000591111.1_Missense_Mutation_p.T33852S|TTN-AS1_ENST00000589842.1_RNA|TTN-AS1_ENST00000590807.1_RNA|TTN_ENST00000460472.2_Missense_Mutation_p.T26428S|TTN_ENST00000342175.6_Missense_Mutation_p.T26620S|TTN-AS1_ENST00000592689.1_RNA|TTN-AS1_ENST00000585625.1_RNA|TTN-AS1_ENST00000592750.1_RNA|TTN-AS1_ENST00000589434.1_RNA|TTN_ENST00000342992.6_Missense_Mutation_p.T32925S|TTN-AS1_ENST00000591867.1_RNA|TTN-AS1_ENST00000442329.2_RNA|TTN-AS1_ENST00000431259.2_RNA|TTN-AS1_ENST00000419746.1_RNA|TTN-AS1_ENST00000591332.1_RNA|TTN-AS1_ENST00000586452.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	33852							ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			TTTTTTACTGTACAAGTATAA	0.348000													16	54					0	0	1	0	0
FLNC	2318	broad.mit.edu	37	7	128470957	128470957	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr7:128470957G>A	ENST00000325888.8	+	1	527	c.266G>A	c.(265-267)cGc>cAc	p.R89H	FLNC_ENST00000346177.6_Missense_Mutation_p.R89H	NM_001458.4	NP_001449.3	Q14315	FLNC_HUMAN	filamin C, gamma	89	Actin-binding.|CH 1.				cell junction assembly	cytoskeleton|cytosol|plasma membrane|sarcomere	actin binding			biliary_tract(1)|breast(7)|central_nervous_system(1)|cervix(1)|endometrium(19)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(19)|lung(59)|ovary(2)|pancreas(2)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)	128						TTCCATCCGCGCCCCAACTTC	0.652000													20	66					0	0	1	0	0
IGF1R	3480	broad.mit.edu	37	15	99192881	99192881	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr15:99192881C>T	ENST00000268035.6	+	1	682	c.71C>T	c.(70-72)tCg>tTg	p.S24L	IGF1R_ENST00000558762.1_Missense_Mutation_p.S24L	NM_000875.3	NP_000866.1	P08069	IGF1R_HUMAN	insulin-like growth factor 1 receptor	24					anti-apoptosis|immune response|insulin receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of cell migration|positive regulation of cell proliferation|positive regulation of DNA replication|protein autophosphorylation|protein tetramerization	microsome	ATP binding|identical protein binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor I binding|insulin-like growth factor receptor activity|metal ion binding|phosphatidylinositol 3-kinase binding			NS(2)|breast(1)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(13)|lung(20)|ovary(1)|prostate(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	63	all_cancers(4;4.17e-14)|all_epithelial(3;4.34e-15)|Lung NSC(78;0.00175)|all_lung(78;0.00351)|Melanoma(26;0.00505)|Medulloblastoma(229;0.163)		Epithelial(2;1.94e-12)|all cancers(5;6.83e-11)|BRCA - Breast invasive adenocarcinoma(2;2.88e-09)|OV - Ovarian serous cystadenocarcinoma(32;0.00261)		Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)|Mecasermin(DB01277)	GCCGCGCTCTCGCTCTGGCCG	0.622000													13	30					0	0	1	0	0
TUBB8P7	197331	broad.mit.edu	37	16	90161926	90161926	+	RNA	SNP	T	T	C	rs8061283	by1000genomes	TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr16:90161926T>C	ENST00000564451.1	+	0	1279				TUBB8P7_ENST00000567960.1_RNA														p.I221T(3)									CCCACACCCATCTATGGTGAC	0.527000													4	19					0	0	1	0	0
LOC101927060	101927060	broad.mit.edu	37	17	45128792	45128792	+	RNA	SNP	G	G	T	rs143713325	by1000genomes	TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:45128792G>T	ENST00000575173.1	-	0	418																											AATTCAGGTTGTCAGAATGCA	0.373000													4	54					0.00909568	0.00946693	1	1	0
KIAA2022	340533	broad.mit.edu	37	X	73964003	73964003	+	Missense_Mutation	SNP	C	C	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chrX:73964003C>A	ENST00000055682.6	-	3	1000	c.389G>T	c.(388-390)gGc>gTc	p.G130V		NM_001008537.2	NP_001008537.1	Q5QGS0	K2022_HUMAN	KIAA2022						base-excision repair, gap-filling|DNA replication proofreading|DNA replication, removal of RNA primer|nucleotide-excision repair, DNA gap filling|regulation of mitotic cell cycle|S phase of mitotic cell cycle	delta DNA polymerase complex	3'-5'-exodeoxyribonuclease activity|DNA-directed DNA polymerase activity			breast(2)|central_nervous_system(2)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(23)|liver(1)|lung(41)|ovary(7)|pancreas(2)|prostate(4)|skin(9)|upper_aerodigestive_tract(2)|urinary_tract(3)	109						AGCTGACATGCCTGCAGGCTC	0.507000													40	20					8.16904e-11	8.67961e-11	1	1	0
ECHDC2	55268	broad.mit.edu	37	1	53377301	53377301	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:53377301G>A	ENST00000536120.1	-	6	893	c.76C>T	c.(76-78)Cgg>Tgg	p.R26W	ECHDC2_ENST00000480312.2_5'UTR|ECHDC2_ENST00000541281.1_Missense_Mutation_p.R26W|ECHDC2_ENST00000358358.5_Missense_Mutation_p.R72W|ECHDC2_ENST00000371522.4_Missense_Mutation_p.R72W			Q86YB7	ECHD2_HUMAN	enoyl CoA hydratase domain containing 2	72					fatty acid metabolic process	mitochondrion	lyase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|urinary_tract(1)	12						CGGTCCTCCCGCAGCTGGGCC	0.612000													3	42					0	0	1	0	0
FRG1B	284802	broad.mit.edu	37	20	29625877	29625877	+	Missense_Mutation	SNP	G	G	A	rs7266938	by1000genomes	TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr20:29625877G>A	ENST00000278882.3	+	5	501	c.121G>A	c.(121-123)Gcc>Acc	p.A41T	FRG1B_ENST00000358464.4_Missense_Mutation_p.A41T|FRG1B_ENST00000439954.2_Missense_Mutation_p.A46T														p.A41T(2)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GTACAGAATCGCCCTGAAATC	0.358000													7	88					0	0	1	0	0
ANAPC5	51433	broad.mit.edu	37	12	121766164	121766164	+	Missense_Mutation	SNP	A	A	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr12:121766164A>G	ENST00000261819.3	-	10	1380	c.1259T>C	c.(1258-1260)aTc>aCc	p.I420T	ANAPC5_ENST00000535482.1_Missense_Mutation_p.I86T|ANAPC5_ENST00000541887.1_Missense_Mutation_p.I407T|ANAPC5_ENST00000544314.1_5'UTR|ANAPC5_ENST00000344395.4_Missense_Mutation_p.I308T|ANAPC5_ENST00000441917.2_Missense_Mutation_p.I308T	NM_016237.4	NP_057321.2	Q9UJX4	APC5_HUMAN	anaphase promoting complex subunit 5	420					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell division|G2/M transition of mitotic cell cycle|mitotic anaphase|mitotic cell cycle spindle assembly checkpoint|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|cytosol|nucleoplasm	protein phosphatase binding|ubiquitin-protein ligase activity			breast(6)|endometrium(3)|kidney(3)|large_intestine(5)|lung(10)|prostate(1)|skin(3)	31	all_neural(191;0.0684)|Medulloblastoma(191;0.0922)					TGCGATGCTGATATCGATGAG	0.547000													10	24					0	0	1	0	0
PTPRC	5788	broad.mit.edu	37	1	198711064	198711064	+	Missense_Mutation	SNP	G	G	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:198711064G>C	ENST00000367376.2	+	24	2635	c.2464G>C	c.(2464-2466)Gtg>Ctg	p.V822L	PTPRC_ENST00000348564.6_Missense_Mutation_p.V663L|PTPRC_ENST00000594404.1_Missense_Mutation_p.V661L|PTPRC_ENST00000442510.2_Missense_Mutation_p.V824L|PTPRC_ENST00000352140.3_Missense_Mutation_p.V774L	NM_002838.4	NP_002829.3	P08575	PTPRC_HUMAN	protein tyrosine phosphatase, receptor type, C	822	Tyrosine-protein phosphatase 1.				axon guidance|B cell proliferation|B cell receptor signaling pathway|defense response to virus|immunoglobulin biosynthetic process|negative regulation of cytokine-mediated signaling pathway|negative regulation of protein kinase activity|negative regulation of T cell mediated cytotoxicity|positive regulation of antigen receptor-mediated signaling pathway|positive regulation of B cell proliferation|positive regulation of protein kinase activity|positive regulation of T cell proliferation|regulation of S phase|release of sequestered calcium ion into cytosol|T cell differentiation|T cell receptor signaling pathway	focal adhesion|integral to plasma membrane|membrane raft	protein kinase binding|transmembrane receptor protein tyrosine phosphatase activity			breast(7)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(22)|lung(41)|ovary(4)|pancreas(2)|prostate(1)|skin(13)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(3)	111						AGACCACGGGGTGCCTGAGGA	0.453000													14	35					0	0	1	0	0
OR4D9	390199	broad.mit.edu	37	11	59282742	59282742	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr11:59282742G>A	ENST00000329328.3	+	1	357	c.357G>A	c.(355-357)gcG>gcA	p.A119A		NM_001004711.1	NP_001004711.1	Q8NGE8	OR4D9_HUMAN	olfactory receptor, family 4, subfamily D, member 9	119					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(1)|kidney(2)|large_intestine(3)|lung(14)|prostate(5)|upper_aerodigestive_tract(1)	26						CTGTGATGGCGTTTGACCGCT	0.522000													7	85					0	0	1	0	0
TGFBR3	7049	broad.mit.edu	37	1	92181894	92181894	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:92181894C>T	ENST00000212355.4	-	12	2230	c.1765G>A	c.(1765-1767)Gga>Aga	p.G589R	TGFBR3_ENST00000525962.1_Missense_Mutation_p.G589R|TGFBR3_ENST00000370399.2_Missense_Mutation_p.G588R	NM_001195683.1|NM_003243.4	NP_001182612.1|NP_003234.2	Q03167	TGBR3_HUMAN	transforming growth factor, beta receptor III	589	ZP.				BMP signaling pathway|cardiac epithelial to mesenchymal transition|cardiac muscle cell proliferation|cell growth|cell migration|definitive erythrocyte differentiation|heart trabecula formation|immune response|intracellular protein kinase cascade|liver development|negative regulation of cellular component movement|negative regulation of epithelial cell proliferation|palate development|pathway-restricted SMAD protein phosphorylation|response to follicle-stimulating hormone stimulus|response to luteinizing hormone stimulus|response to prostaglandin E stimulus|transforming growth factor beta receptor signaling pathway|ventricular cardiac muscle tissue morphogenesis	external side of plasma membrane|extracellular space|inhibin-betaglycan-ActRII complex|integral to plasma membrane|intracellular membrane-bounded organelle	coreceptor activity|heparin binding|PDZ domain binding|SMAD binding|transforming growth factor beta binding|transforming growth factor beta receptor activity, type III|type II transforming growth factor beta receptor binding			endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(24)|ovary(3)|prostate(4)|skin(1)|stomach(1)|urinary_tract(3)	55		all_lung(203;0.00719)|Lung NSC(277;0.0268)		all cancers(265;0.0108)|Epithelial(280;0.0825)		GTGATGTTTCCGTGGGGCTGT	0.483000													16	44					0	0	1	0	0
CSPG4	1464	broad.mit.edu	37	15	75979718	75979718	+	Missense_Mutation	SNP	T	T	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr15:75979718T>C	ENST00000308508.5	-	3	3780	c.3688A>G	c.(3688-3690)Att>Gtt	p.I1230V		NM_001897.4	NP_001888.2	Q6UVK1	CSPG4_HUMAN	chondroitin sulfate proteoglycan 4	1230	Gly/Ser-rich (glycosaminoglycan attachment domain).|Interaction with COL5A1 (By similarity).				angiogenesis|cell differentiation|intracellular signal transduction|positive regulation of peptidyl-tyrosine phosphorylation|tissue remodeling	apical plasma membrane|cell surface|integral to plasma membrane|intracellular|lamellipodium membrane	protein kinase binding|signal transducer activity			breast(1)|cervix(2)|endometrium(5)|kidney(5)|large_intestine(3)|liver(2)|lung(18)|ovary(2)|pancreas(2)|prostate(4)|skin(4)	48						TCTAGGGCAATGGTCACTTGT	0.607000													5	91					0	0	1	0	0
MAGI1	9223	broad.mit.edu	37	3	65342560	65342560	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr3:65342560G>A	ENST00000402939.2	-	23	3881	c.3882C>T	c.(3880-3882)tgC>tgT	p.C1294C	MAGI1_ENST00000330909.8_3'UTR	NM_001033057.1	NP_001028229.1	Q96QZ7	MAGI1_HUMAN	membrane associated guanylate kinase, WW and PDZ domain containing 1	1323					cell adhesion|cell surface receptor linked signaling pathway|protein complex assembly	tight junction	ATP binding|protein C-terminus binding	p.C1294C(2)		breast(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|liver(1)|lung(21)|pancreas(1)|skin(5)	51		Lung NSC(201;0.0016)		BRCA - Breast invasive adenocarcinoma(55;0.00138)|KIRC - Kidney renal clear cell carcinoma(15;0.0988)|Kidney(15;0.133)		CCTTGGGTCGGCATGCCCCGC	0.672000													4	61					0	0	1	0	0
LOC101927060	101927060	broad.mit.edu	37	17	45128812	45128812	+	RNA	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:45128812C>T	ENST00000575173.1	-	0	418																											AGTCCTGTTTCTGTGTGGATT	0.373000													3	42					0	0	1	0	0
STK11IP	114790	broad.mit.edu	37	2	220473305	220473305	+	Splice_Site	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr2:220473305C>T	ENST00000456909.1	+	15	1694	c.1604C>T	c.(1603-1605)gCg>gTg	p.A535V	STK11IP_ENST00000295641.10_Splice_Site_p.A546V			Q8N1F8	S11IP_HUMAN	serine/threonine kinase 11 interacting protein	546	Glu-rich.				protein localization	cytoplasm	protein kinase binding			breast(2)|endometrium(5)|kidney(1)|large_intestine(2)|lung(10)|ovary(1)|prostate(1)|urinary_tract(1)	23		Renal(207;0.0183)		Epithelial(149;2.69e-07)|all cancers(144;5.91e-05)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		CTCTCCACAGCGGAACTCTGT	0.632000													13	32					0	0	1	0	0
PGBD4	161779	broad.mit.edu	37	15	34394773	34394773	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr15:34394773G>A	ENST00000397766.2	+	1	500	c.41G>A	c.(40-42)aGt>aAt	p.S14N		NM_152595.4	NP_689808.2	Q96DM1	PGBD4_HUMAN	piggyBac transposable element derived 4	14										breast(2)|endometrium(1)|kidney(1)|large_intestine(5)|lung(5)|pancreas(1)|prostate(1)	16		all_lung(180;1.76e-08)		all cancers(64;1.22e-17)|GBM - Glioblastoma multiforme(113;1.78e-06)|BRCA - Breast invasive adenocarcinoma(123;0.0242)		atgcgtgatagtaataccggt	0.348000													5	5					0	0	1	0	0
MYOF	26509	broad.mit.edu	37	10	95072807	95072807	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr10:95072807G>A	ENST00000371501.4	-	51	5981	c.5859C>T	c.(5857-5859)taC>taT	p.Y1953Y	MYOF_ENST00000358334.5_Silent_p.Y1940Y|MYOF_ENST00000359263.4_Silent_p.Y1953Y|MYOF_ENST00000371502.4_Silent_p.Y1943Y			Q9NZM1	MYOF_HUMAN	myoferlin	1953					blood circulation|muscle contraction|plasma membrane repair	caveola|cytoplasmic vesicle membrane|integral to membrane|nuclear membrane	phospholipid binding|protein binding			NS(2)|autonomic_ganglia(1)|breast(3)|endometrium(7)|kidney(7)|large_intestine(15)|lung(14)|ovary(4)|prostate(4)|skin(6)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	67						CTTTCTCTGCGTAGCATGGCC	0.473000													11	318					0	0	1	0	0
HIST2H3D	653604	broad.mit.edu	37	1	149784871	149784871	+	Silent	SNP	G	G	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:149784871G>C	ENST00000331491.1	-	1	365	c.366C>G	c.(364-366)ccC>ccG	p.P122P		NM_001123375.2	NP_001116847.1	Q71DI3	H32_HUMAN	histone cluster 2, H3d	122					blood coagulation|nucleosome assembly	nucleoplasm|nucleosome	DNA binding|protein binding			biliary_tract(1)|endometrium(1)|large_intestine(1)|liver(1)|lung(3)	7						GGATGTCCTTGGGCATGATGG	0.602000													20	47					0	0	1	0	0
NPHP1	4867	broad.mit.edu	37	2	110904384	110904384	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr2:110904384C>T	ENST00000316534.4	-	14	1539	c.1466G>A	c.(1465-1467)tGt>tAt	p.C489Y	NPHP1_ENST00000445609.2_Missense_Mutation_p.C433Y|NPHP1_ENST00000355301.4_Missense_Mutation_p.C370Y|NPHP1_ENST00000417665.1_Missense_Mutation_p.C432Y|NPHP1_ENST00000393272.3_Missense_Mutation_p.C488Y			O15259	NPHP1_HUMAN	nephronophthisis 1 (juvenile)	488					actin cytoskeleton organization|cell projection organization|cell-cell adhesion|excretion|retina development in camera-type eye|signal transduction|spermatid differentiation|visual behavior	adherens junction|cell-cell junction|cilium axoneme|cytoplasm|cytoskeleton|motile cilium|photoreceptor connecting cilium	protein binding|structural molecule activity			autonomic_ganglia(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(6)|lung(10)|ovary(2)	24						CACCCAGCCACAGCTTAACTC	0.358000													19	51					0	0	1	0	0
BNC2	54796	broad.mit.edu	37	9	16727916	16727916	+	Nonsense_Mutation	SNP	A	A	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr9:16727916A>C	ENST00000380672.4	-	3	266	c.209T>G	c.(208-210)tTa>tGa	p.L70*	BNC2_ENST00000545497.1_Intron|BNC2_ENST00000380667.2_Intron|BNC2_ENST00000380666.2_Nonsense_Mutation_p.L70*	NM_017637.5	NP_060107.3	Q6ZN30	BNC2_HUMAN	basonuclin 2	70					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus|plasma membrane	zinc ion binding			NS(2)|breast(3)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(16)|liver(1)|lung(22)|ovary(2)|prostate(1)|skin(1)|urinary_tract(2)	60				GBM - Glioblastoma multiforme(50;9.01e-08)		GGAGTCTCTTAAAGTCAAGtc	0.483000													35	70					0	0	1	0	0
TLL2	7093	broad.mit.edu	37	10	98129890	98129890	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr10:98129890C>T	ENST00000357947.3	-	20	3070	c.2845G>A	c.(2845-2847)Gac>Aac	p.D949N		NM_012465.3	NP_036597.1	Q9Y6L7	TLL2_HUMAN	tolloid-like 2	949	CUB 5.				cell differentiation|multicellular organismal development|proteolysis	extracellular region	calcium ion binding|metalloendopeptidase activity|zinc ion binding			NS(1)|breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(5)|large_intestine(15)|lung(22)|ovary(1)|pancreas(1)|prostate(1)|skin(3)	58		Colorectal(252;0.0846)		Epithelial(162;1.51e-07)|all cancers(201;7.59e-06)		TCCATGTAGTCGTAGCCGCAG	0.662000													15	18					0	0	1	0	0
GIT1	28964	broad.mit.edu	37	17	27908355	27908355	+	Splice_Site	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:27908355C>T	ENST00000225394.3	-	7	1010		c.e7+1		GIT1_ENST00000579937.1_Splice_Site|GIT1_ENST00000581348.1_Splice_Site|RP11-68I3.2_ENST00000581474.1_RNA|GIT1_ENST00000394869.3_Splice_Site	NM_014030.3	NP_054749.2	Q9Y2X7	GIT1_HUMAN	G protein-coupled receptor kinase interacting ArfGAP 1						regulation of ARF GTPase activity|regulation of G-protein coupled receptor protein signaling pathway	cytoplasm|focal adhesion	ARF GTPase activator activity|protein binding|zinc ion binding			large_intestine(2)|lung(3)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	9				READ - Rectum adenocarcinoma(3;0.0419)|Colorectal(3;0.069)		TGGGCACTCACCTGTCAGCCA	0.552000													9	33					0	0	1	0	0
LTN1	26046	broad.mit.edu	37	21	30354657	30354657	+	Missense_Mutation	SNP	C	C	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr21:30354657C>G	ENST00000389194.2	-	5	753	c.748G>C	c.(748-750)Gat>Cat	p.D250H	LTN1_ENST00000361371.5_Missense_Mutation_p.D204H|LTN1_ENST00000389195.2_Missense_Mutation_p.D250H	NM_015565.2	NP_056380.2	O94822	LTN1_HUMAN	listerin E3 ubiquitin protein ligase 1	204							ligase activity|zinc ion binding			NS(1)|central_nervous_system(1)|endometrium(4)|kidney(5)|large_intestine(12)|lung(19)|ovary(5)|pancreas(1)|prostate(2)|skin(6)|stomach(2)|upper_aerodigestive_tract(2)	60						CTGAGTGTATCAGGTGTTTCT	0.383000													23	51					0	0	1	0	0
WNK4	65266	broad.mit.edu	37	17	40940794	40940794	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:40940794G>A	ENST00000246914.5	+	11	2157	c.2136G>A	c.(2134-2136)ccG>ccA	p.P712P		NM_032387.4	NP_115763.2	Q96J92	WNK4_HUMAN	WNK lysine deficient protein kinase 4	712					intracellular protein kinase cascade	tight junction	ATP binding|protein serine/threonine kinase activity			NS(1)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(10)|ovary(3)|prostate(1)|skin(5)|stomach(1)	35		Breast(137;0.000143)		BRCA - Breast invasive adenocarcinoma(366;0.0749)		GGGACAGCCCGGAAGAGATTG	0.532000													12	39					0	0	1	0	0
SEC14L5	9717	broad.mit.edu	37	16	5055945	5055945	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr16:5055945C>T	ENST00000251170.7	+	12	1513	c.1333C>T	c.(1333-1335)Cgg>Tgg	p.R445W		NM_014692.1	NP_055507.1	O43304	S14L5_HUMAN	SEC14-like 5 (S. cerevisiae)	445	CRAL-TRIO.					integral to membrane|intracellular	transporter activity			NS(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(7)|lung(9)|ovary(1)|skin(1)	29						GAACACCAGGCGGAAGTTCCT	0.483000													4	8					0	0	1	0	0
MYLK	4638	broad.mit.edu	37	3	123359181	123359181	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr3:123359181G>A	ENST00000360772.3	-	29	5168	c.4790C>T	c.(4789-4791)aCg>aTg	p.T1597M	MYLK_ENST00000360304.3_Missense_Mutation_p.T1597M|MYLK_ENST00000346322.5_Missense_Mutation_p.T1528M|MYLK_ENST00000475616.1_Missense_Mutation_p.T1597M|MYLK_ENST00000359169.1_Missense_Mutation_p.T1597M|MYLK-AS1_ENST00000485162.1_RNA|MYLK_ENST00000354792.5_Missense_Mutation_p.T397M			Q15746	MYLK_HUMAN	myosin light chain kinase	1597	Protein kinase.				aorta smooth muscle tissue morphogenesis|muscle contraction	cytosol	actin binding|ATP binding|calmodulin binding|metal ion binding|myosin light chain kinase activity			NS(2)|breast(4)|central_nervous_system(1)|endometrium(24)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(17)|lung(37)|ovary(7)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	113		Lung NSC(201;0.0496)		GBM - Glioblastoma multiforme(114;0.0736)		CCTGGTGCCCGTCTTGTTGAC	0.562000													4	113					0	0	1	0	0
BRCA2	675	broad.mit.edu	37	13	32914649	32914649	+	Missense_Mutation	SNP	T	T	C			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr13:32914649T>C	ENST00000544455.1	+	11	6384	c.6157T>C	c.(6157-6159)Tct>Cct	p.S2053P	BRCA2_ENST00000380152.3_Missense_Mutation_p.S2053P	NM_000059.3	NP_000050	P51587	BRCA2_HUMAN	breast cancer 2, early onset	2053					cell cycle cytokinesis|centrosome duplication|double-strand break repair via homologous recombination|negative regulation of mammary gland epithelial cell proliferation|nucleotide-excision repair|positive regulation of transcription, DNA-dependent|regulation of S phase of mitotic cell cycle	BRCA2-MAGE-D1 complex|centrosome|nucleoplasm|stored secretory granule	gamma-tubulin binding|H3 histone acetyltransferase activity|H4 histone acetyltransferase activity|protease binding|single-stranded DNA binding			NS(3)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(24)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(32)|liver(1)|lung(41)|oesophagus(5)|ovary(22)|pancreas(4)|prostate(3)|salivary_gland(1)|skin(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	183		Lung SC(185;0.0262)		all cancers(112;7.13e-07)|Epithelial(112;1.59e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.000732)|BRCA - Breast invasive adenocarcinoma(63;0.0291)|GBM - Glioblastoma multiforme(144;0.0704)		GGTAAATTCATCTGCTTTCTC	0.348000			"""D, Mis, N, F, S"""		"""breast, ovarian, pancreatic"""	"""breast, ovarian, pancreatic, leukemia  (FANCB, FANCD1)"""		Homologous recombination	Pancreatic Cancer, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Prostate Cancer;Hereditary Breast-Ovarian Cancer, BRCA2 type;Fanconi Anemia type D1, bi-allelic BRCA2 mutations;Fanconi Anemia	TCGA Ovarian(8;0.087)			21	17					0	0	1	0	0
TBX19	9095	broad.mit.edu	37	1	168282171	168282171	+	Silent	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:168282171G>A	ENST00000367821.3	+	8	1329	c.1278G>A	c.(1276-1278)tcG>tcA	p.S426S	TBX19_ENST00000465440.1_3'UTR	NM_005149.2	NP_005140.1	O60806	TBX19_HUMAN	T-box 19	426					anatomical structure morphogenesis	nucleus	DNA binding			NS(1)|breast(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|liver(1)|lung(11)|prostate(2)|skin(2)|urinary_tract(1)	34	all_hematologic(923;0.215)					CAGTGGCCTCGCATCCCTTCG	0.627000													9	29					0	0	1	0	0
KRT79	338785	broad.mit.edu	37	12	53227629	53227629	+	Missense_Mutation	SNP	C	C	G	rs140416696	byFrequency	TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr12:53227629C>G	ENST00000330553.5	-	1	450	c.416G>C	c.(415-417)cGc>cCc	p.R139P		NM_175834.2	NP_787028.1	Q5XKE5	K2C79_HUMAN	keratin 79	139	Head.					keratin filament	structural molecule activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(11)|ovary(2)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	30						CTCCTGAGTGCGCACTCGCTG	0.607000													34	96					0	0	1	0	0
KCTD1	284252	broad.mit.edu	37	18	24039836	24039836	+	Missense_Mutation	SNP	C	C	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr18:24039836C>G	ENST00000417602.1	-	4	2186	c.2187G>C	c.(2185-2187)ttG>ttC	p.L729F	KCTD1_ENST00000579973.1_Missense_Mutation_p.L121F|KCTD1_ENST00000317932.7_Missense_Mutation_p.L121F|KCTD1_ENST00000408011.3_Missense_Mutation_p.L121F|KCTD1_ENST00000580059.1_Missense_Mutation_p.L121F	NM_001142730.2	NP_001136202.1	Q719H9	KCTD1_HUMAN	potassium channel tetramerization domain containing 1	121					negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus|voltage-gated potassium channel complex	transcription corepressor activity|transcription factor binding|voltage-gated potassium channel activity			endometrium(2)|large_intestine(3)|lung(3)|ovary(1)|prostate(3)	12	all_cancers(21;0.00191)|Lung NSC(5;0.000698)|all_lung(6;0.0019)|Ovarian(20;0.0848)		Epithelial(2;7.8e-06)|OV - Ovarian serous cystadenocarcinoma(3;9.02e-06)|all cancers(3;3.37e-05)			CCATCTCCAACAACATGGGCT	0.448000													10	124					0	0	1	0	0
ACTRT3	84517	broad.mit.edu	37	3	169486095	169486095	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr3:169486095C>T	ENST00000330368.2	-	2	618	c.244G>A	c.(244-246)Gag>Aag	p.E82K		NM_032487.4	NP_115876.3	Q9BYD9	ARPM1_HUMAN	actin-related protein T3	82						cytoplasm|cytoskeleton											CACATGATCTCCATGTCCTCC	0.448000													13	39					0	0	1	0	0
UGT2B4	7363	broad.mit.edu	37	4	70346534	70346534	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr4:70346534G>A	ENST00000305107.6	-	6	1451	c.1405C>T	c.(1405-1407)Cgc>Tgc	p.R469C	UGT2B4_ENST00000381096.3_Missense_Mutation_p.R333C|UGT2B4_ENST00000506580.1_5'UTR|UGT2B4_ENST00000512583.1_3'UTR	NM_021139.2	NP_066962.2	P06133	UD2B4_HUMAN	UDP glucuronosyltransferase 2 family, polypeptide B4	469					estrogen catabolic process|xenobiotic metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity			autonomic_ganglia(1)|breast(1)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(3)|lung(29)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)	47						CCTTTATGGCGCATGACAAAT	0.478000													45	136					0	0	1	0	0
MED23	9439	broad.mit.edu	37	6	131923454	131923454	+	Missense_Mutation	SNP	G	G	A			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr6:131923454G>A	ENST00000403834.3	-	17	2190	c.2017C>T	c.(2017-2019)Cgc>Tgc	p.R673C	MED23_ENST00000354577.4_Missense_Mutation_p.R673C|MED23_ENST00000539158.1_3'UTR|MED23_ENST00000368068.3_Missense_Mutation_p.R667C|MED23_ENST00000368053.4_Missense_Mutation_p.R673C|MED23_ENST00000368058.1_Missense_Mutation_p.R673C|MED23_ENST00000368060.3_Missense_Mutation_p.R667C|MED23_ENST00000540546.1_Missense_Mutation_p.R673C|MED23_ENST00000545957.1_Missense_Mutation_p.R308C			Q9ULK4	MED23_HUMAN	mediator complex subunit 23	667					regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	transcription factor complex	protein binding|transcription coactivator activity			NS(1)|breast(3)|central_nervous_system(1)|endometrium(1)|kidney(4)|large_intestine(12)|lung(15)|ovary(1)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)	44	Breast(56;0.0753)			GBM - Glioblastoma multiforme(226;0.0115)|OV - Ovarian serous cystadenocarcinoma(155;0.0608)		CTAAGGAAGCGTGTAAACTGC	0.433000													4	105					0	0	1	0	0
PCDHB3	56132	broad.mit.edu	37	5	140482266	140482266	+	Missense_Mutation	SNP	C	C	T			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr5:140482266C>T	ENST00000231130.2	+	1	2033	c.2033C>T	c.(2032-2034)cCg>cTg	p.P678L		NM_018937.2	NP_061760.1	Q9Y5E6	PCDB3_HUMAN		678					calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			NS(2)|breast(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(19)|lung(24)|ovary(1)|pancreas(1)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(3)	72			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GAGGCGGCACCGGCCCAGGCC	0.672000													45	117					0	0	1	0	0
EGFR	1956	broad.mit.edu	37	7	55210075	55210075	+	Missense_Mutation	SNP	T	T	G			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr7:55210075T>G	ENST00000275493.2	+	2	362	c.185T>G	c.(184-186)cTt>cGt	p.L62R	EGFR_ENST00000342916.3_Missense_Mutation_p.L62R|EGFR_ENST00000344576.2_Missense_Mutation_p.L62R|EGFR_ENST00000454757.2_Missense_Mutation_p.L9R|EGFR_ENST00000442591.1_Missense_Mutation_p.L62R|EGFR_ENST00000420316.2_Missense_Mutation_p.L62R|EGFR_ENST00000455089.1_Missense_Mutation_p.L62R	NM_005228.3	NP_005219.2	P00533	EGFR_HUMAN	epidermal growth factor receptor	62					activation of phospholipase A2 activity by calcium-mediated signaling|activation of phospholipase C activity|axon guidance|cell proliferation|cell-cell adhesion|negative regulation of apoptosis|negative regulation of epidermal growth factor receptor signaling pathway|ossification|positive regulation of catenin import into nucleus|positive regulation of cell migration|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|positive regulation of epithelial cell proliferation|positive regulation of MAP kinase activity|positive regulation of nitric oxide biosynthetic process|positive regulation of phosphorylation|positive regulation of protein kinase B signaling cascade|protein autophosphorylation|protein insertion into membrane|regulation of nitric-oxide synthase activity|regulation of peptidyl-tyrosine phosphorylation|response to stress|response to UV-A	basolateral plasma membrane|endoplasmic reticulum membrane|endosome|extracellular space|Golgi membrane|integral to membrane|nuclear membrane|Shc-EGFR complex	actin filament binding|ATP binding|double-stranded DNA binding|epidermal growth factor receptor activity|identical protein binding|MAP/ERK kinase kinase activity|protein heterodimerization activity|protein phosphatase binding|receptor signaling protein tyrosine kinase activity	p.L62R(3)		NS(2)|adrenal_gland(5)|biliary_tract(8)|bone(3)|breast(18)|central_nervous_system(106)|endometrium(26)|eye(3)|haematopoietic_and_lymphoid_tissue(9)|kidney(11)|large_intestine(85)|liver(2)|lung(13575)|oesophagus(21)|ovary(38)|pancreas(3)|peritoneum(11)|pleura(2)|prostate(35)|salivary_gland(11)|skin(9)|small_intestine(1)|soft_tissue(4)|stomach(41)|thymus(2)|thyroid(14)|upper_aerodigestive_tract(59)|urinary_tract(6)	14110	all_cancers(1;1.57e-46)|all_epithelial(1;5.62e-37)|Lung NSC(1;9.29e-25)|all_lung(1;4.39e-23)|Esophageal squamous(2;7.55e-08)|Breast(14;0.0318)		GBM - Glioblastoma multiforme(1;0)|all cancers(1;2.19e-314)|Lung(13;4.65e-05)|LUSC - Lung squamous cell carcinoma(13;0.000168)|STAD - Stomach adenocarcinoma(5;0.00164)|Epithelial(13;0.0607)		Cetuximab(DB00002)|Erlotinib(DB00530)|Gefitinib(DB00317)|Lapatinib(DB01259)|Lidocaine(DB00281)|Panitumumab(DB01269)|Trastuzumab(DB00072)	GAGGTGGTCCTTGGGAATTTG	0.408000		8	"""A, O, Mis"""		"""glioma, NSCLC"""	NSCLC			Lung Cancer, Familial Clustering of	TCGA GBM(3;<1E-08)|TSP Lung(4;<1E-08)			1332	72					0	0	1	0	0
RP11-435B5.5	0	broad.mit.edu	37	1	143391935	143391936	+	RNA	INS	-	-	TG			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr1:143391935_143391936insTG	ENST00000428624.1	+	0	2065				RP11-435B5.4_ENST00000423249.1_lincRNA																							ATATATATATATAAAGAGATTG	0.252													4	9	---	---	---	---					
RPL24	6152	broad.mit.edu	37	3	101401316	101401316	+	Frame_Shift_Del	DEL	T	T	-			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr3:101401316delT	ENST00000469605.1	-	5	368	c.350delA	c.(349-351)aagfs	p.K117fs	RPL24_ENST00000495401.1_Intron|RPL24_ENST00000394077.3_Frame_Shift_Del_p.K117fs			P83731	RL24_HUMAN	ribosomal protein L24	117					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic large ribosomal subunit	protein binding|RNA binding|structural constituent of ribosome			large_intestine(1)|lung(2)|urinary_tract(1)	4						TTGCTTAGCCTTTTTTGCTTC	0.368													7	147	---	---	---	---					
MAML3	55534	broad.mit.edu	37	4	140811064	140811069	+	In_Frame_Del	DEL	TGCTGC	TGCTGC	-	rs71855026		TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr4:140811064_140811069delTGCTGC	ENST00000509479.2	-	2	2377_2382	c.1521_1526delGCAGCA	c.(1519-1527)cagcagcaa>caa	p.507_509QQQ>Q	MAML3_ENST00000398940.1_Splice_Site_p.A37del|MAML3_ENST00000327122.5_In_Frame_Del_p.351_353QQQ>Q	NM_018717.4	NP_061187	Q96JK9	MAML3_HUMAN	mastermind-like 3 (Drosophila)	506	Gln-rich.				Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	transcription coactivator activity			breast(1)|endometrium(7)|kidney(2)|large_intestine(1)|lung(9)|ovary(1)|prostate(2)|urinary_tract(2)	25	all_hematologic(180;0.162)					TGAGtgctgttgctgctgctgctgct	0.515													7	67	---	---	---	---					
SAMD5	389432	broad.mit.edu	37	6	148018465	148018465	+	RNA	DEL	A	A	-			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr6:148018465delA	ENST00000427015.1	+	0	117																											TTTGTTCTCTAAACCCAGTTT	0.388													2	4	---	---	---	---					
LOC102723841	102723841	broad.mit.edu	37	16	33365420	33365420	+	RNA	DEL	A	A	-			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr16:33365420delA	ENST00000568520.1	-	0	249																											TACAAACTATAAAAAAACAGA	0.358													4	3	---	---	---	---					
NF1	4763	broad.mit.edu	37	17	29562708	29562710	+	In_Frame_Del	DEL	AAG	AAG	-			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr17:29562708_29562710delAAG	ENST00000358273.4	+	28	4171_4173	c.3788_3790delAAG	c.(3787-3792)aaagaa>aaa	p.E1264del	NF1_ENST00000356175.3_In_Frame_Del_p.E1264del	NM_001042492.2	NP_001035957.1	P21359	NF1_HUMAN	neurofibromin 1	1264	Ras-GAP.				actin cytoskeleton organization|adrenal gland development|artery morphogenesis|camera-type eye morphogenesis|cerebral cortex development|collagen fibril organization|forebrain astrocyte development|forebrain morphogenesis|heart development|liver development|MAPKKK cascade|metanephros development|myelination in peripheral nervous system|negative regulation of cell migration|negative regulation of endothelial cell proliferation|negative regulation of MAP kinase activity|negative regulation of MAPKKK cascade|negative regulation of neuroblast proliferation|negative regulation of oligodendrocyte differentiation|negative regulation of transcription factor import into nucleus|osteoblast differentiation|phosphatidylinositol 3-kinase cascade|pigmentation|positive regulation of adenylate cyclase activity|positive regulation of neuron apoptosis|Ras protein signal transduction|regulation of blood vessel endothelial cell migration|regulation of bone resorption|response to hypoxia|smooth muscle tissue development|spinal cord development|sympathetic nervous system development|visual learning|wound healing	axon|cytoplasm|dendrite|intrinsic to internal side of plasma membrane|nucleus	protein binding|Ras GTPase activator activity	p.0?(8)|p.?(4)|p.E1264K(1)	NF1/ACCN1(2)	autonomic_ganglia(12)|breast(11)|central_nervous_system(72)|cervix(6)|endometrium(12)|haematopoietic_and_lymphoid_tissue(59)|kidney(9)|large_intestine(39)|liver(1)|lung(80)|ovary(20)|pancreas(2)|prostate(2)|skin(8)|soft_tissue(249)|stomach(2)|thyroid(1)|upper_aerodigestive_tract(5)|urinary_tract(9)	599		all_cancers(10;1.29e-12)|all_epithelial(10;0.00347)|all_hematologic(16;0.00556)|Acute lymphoblastic leukemia(14;0.00593)|Breast(31;0.014)|Myeloproliferative disorder(56;0.0255)|all_lung(9;0.0321)|Lung NSC(157;0.0659)		UCEC - Uterine corpus endometrioid carcinoma (4;4.38e-05)|all cancers(4;1.64e-26)|Epithelial(4;9.15e-23)|OV - Ovarian serous cystadenocarcinoma(4;3.58e-21)|GBM - Glioblastoma multiforme(4;0.00146)		ATGTTTTCTAAAGAAGTAGAATT	0.399			"""D, Mis, N, F, S, O"""		"""neurofibroma, glioma"""	"""neurofibroma, glioma"""			Neurofibromatosis, type 1	TCGA GBM(6;<1E-08)|TSP Lung(7;0.0071)|TCGA Ovarian(3;0.0088)			69	196	---	---	---	---					
FCGRT	2217	broad.mit.edu	37	19	50028814	50028816	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-S9-A7IX-01A-12D-A34A-08	TCGA-S9-A7IX-10A-01D-A34A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7b2fa849-8bef-4071-b65b-311633bdb61d	9022575a-72fa-44e3-b975-10d3c60e6297	g.chr19:50028814_50028816delGAG	ENST00000221466.5	+	6	1458_1460	c.972_974delGAG	c.(970-975)atgagg>atg	p.R325del	FCGRT_ENST00000426395.3_In_Frame_Del_p.R325del|FCGRT_ENST00000599988.1_In_Frame_Del_p.R59del|FCGRT_ENST00000596975.1_In_Frame_Del_p.R233del	NM_001136019.2	NP_001129491.1	P55899	FCGRN_HUMAN	Fc fragment of IgG, receptor, transporter, alpha	325					antigen processing and presentation|female pregnancy|immune response	integral to membrane|MHC class I protein complex	IgG binding|receptor activity			endometrium(3)|kidney(2)|lung(1)|ovary(1)|prostate(1)|skin(1)	9		all_lung(116;7.84e-06)|Lung NSC(112;2.8e-05)|all_neural(266;0.0966)|Ovarian(192;0.231)		OV - Ovarian serous cystadenocarcinoma(262;0.00291)|GBM - Glioblastoma multiforme(134;0.0156)		GGAGAAGGATGAGGAGTGGGCTG	0.616													13	24	---	---	---	---					
