Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ARHGAP32	9743	broad.mit.edu	37	11	128848708	128848708	+	Silent	SNP	C	C	G			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr11:128848708C>G	ENST00000310343.9	-	18	2036	c.2037G>C	c.(2035-2037)cgG>cgC	p.R679R	ARHGAP32_ENST00000527272.1_Silent_p.R330R|ARHGAP32_ENST00000392657.3_Silent_p.R330R|ARHGAP32_ENST00000524655.1_Silent_p.R605R	NM_001142685.1	NP_001136157.1	A7KAX9	RHG32_HUMAN	Rho GTPase activating protein 32	679					cell communication|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cell cortex|cell junction|cytosol|dendritic spine|endoplasmic reticulum membrane|endosome membrane|Golgi membrane|postsynaptic density|postsynaptic membrane	GTPase activator activity|phosphatidylinositol binding			breast(2)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(12)|lung(28)|ovary(3)|prostate(6)|urinary_tract(3)	60						CACTCTCATTCCGCTGCAGCT	0.468000													15	37					0	0	1	0	0
FASN	2194	broad.mit.edu	37	17	80040931	80040931	+	Missense_Mutation	SNP	T	T	C			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr17:80040931T>C	ENST00000306749.2	-	33	5844	c.5626A>G	c.(5626-5628)Atc>Gtc	p.I1876V	FASN_ENST00000579758.1_5'UTR	NM_004104.4	NP_004095.4	P49327	FAS_HUMAN	fatty acid synthase	1876	Beta-ketoacyl reductase (By similarity).				energy reserve metabolic process|fatty acid biosynthetic process|long-chain fatty-acyl-CoA biosynthetic process|pantothenate metabolic process|positive regulation of cellular metabolic process|triglyceride biosynthetic process	cytosol|Golgi apparatus|melanosome|plasma membrane	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity|3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity|3-oxoacyl-[acyl-carrier-protein] synthase activity|[acyl-carrier-protein] S-acetyltransferase activity|[acyl-carrier-protein] S-malonyltransferase activity|acyl carrier activity|cofactor binding|enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity|myristoyl-[acyl-carrier-protein] hydrolase activity|oleoyl-[acyl-carrier-protein] hydrolase activity|palmitoyl-[acyl-carrier-protein] hydrolase activity|phosphopantetheine binding|protein binding|zinc ion binding			central_nervous_system(3)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(12)|prostate(3)|skin(2)|urinary_tract(1)	34	all_neural(118;0.0878)|Ovarian(332;0.227)|all_lung(278;0.246)		OV - Ovarian serous cystadenocarcinoma(97;0.0211)|BRCA - Breast invasive adenocarcinoma(99;0.0237)		Cerulenin(DB01034)|Orlistat(DB01083)|Pyrazinamide(DB00339)	GTCTTGGAGATGGCCGACATC	0.647000													24	18					0	0	1	0	0
KRT23	25984	broad.mit.edu	37	17	39092548	39092548	+	Missense_Mutation	SNP	C	C	T			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr17:39092548C>T	ENST00000209718.3	-	2	732	c.308G>A	c.(307-309)cGc>cAc	p.R103H	AC004231.2_ENST00000418393.1_RNA|KRT23_ENST00000436344.3_Intron	NM_015515.3	NP_056330.3	Q9C075	K1C23_HUMAN	keratin 23 (histone deacetylase inducible)	103	Coil 1A.|Rod.					intermediate filament	structural molecule activity			central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	21		Breast(137;0.000301)|Ovarian(249;0.15)				TTTCAGGATGCGGCTTTCCAG	0.542000													4	122					0	0	1	0	0
TCP10L2	401285	broad.mit.edu	37	6	167585686	167585686	+	Silent	SNP	G	G	A	rs35001773		TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr6:167585686G>A	ENST00000366832.2	+	2	185	c.54G>A	c.(52-54)gaG>gaA	p.E18E		NM_001145121.1	NP_001138593.1	B9ZVM9	B9ZVM9_HUMAN	t-complex 10-like 2	18										endometrium(1)|kidney(2)|lung(3)	6						CCCACCCAGAGGACCCGTGCC	0.662000													6	15					0	0	1	0	0
HIST1H2AA	221613	broad.mit.edu	37	6	25726459	25726459	+	Silent	SNP	G	G	A			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr6:25726459G>A	ENST00000297012.3	-	1	331	c.297C>T	c.(295-297)ggC>ggT	p.G99G		NM_170745.3	NP_734466.1	Q96QV6	H2A1A_HUMAN	histone cluster 1, H2aa	99					nucleosome assembly	nucleosome|nucleus	DNA binding			breast(1)|endometrium(2)|large_intestine(2)|lung(8)	13						TGGTCACGCCGCCCAAAAGCT	0.532000													64	80					0	0	1	0	0
OR8I2	120586	broad.mit.edu	37	11	55861593	55861593	+	Silent	SNP	G	G	A			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr11:55861593G>A	ENST00000302124.2	+	1	841	c.810G>A	c.(808-810)gcG>gcA	p.A270A		NM_001003750.1	NP_001003750.1	Q8N0Y5	OR8I2_HUMAN	olfactory receptor, family 8, subfamily I, member 2	270					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.A270A(15)		NS(1)|breast(2)|endometrium(16)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(4)|lung(24)|ovary(1)|skin(2)|upper_aerodigestive_tract(1)	53	Esophageal squamous(21;0.00693)					TGACCCAGGCGCAGGTGGCAT	0.453000													3	59					0	0	1	0	0
REG1A	5967	broad.mit.edu	37	2	79349251	79349251	+	Splice_Site	SNP	G	G	A			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr2:79349251G>A	ENST00000233735.1	+	4	424	c.321G>A	c.(319-321)aaG>aaA	p.K107K		NM_002909.4	NP_002900.2	P05451	REG1A_HUMAN	regenerating islet-derived 1 alpha	107	C-type lectin.				positive regulation of cell proliferation	extracellular region	growth factor activity|sugar binding			NS(1)|breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(5)|lung(26)|prostate(1)|upper_aerodigestive_tract(1)	39						ACCCCAAAAAGGTAGGCTGCA	0.488000													28	44					0	0	1	0	0
KY	339855	broad.mit.edu	37	3	134323111	134323111	+	Silent	SNP	C	C	T			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr3:134323111C>T	ENST00000508956.1	-	10	1290	c.1233G>A	c.(1231-1233)acG>acA	p.T411T	KY_ENST00000423778.2_Silent_p.T432T|KY_ENST00000503669.1_3'UTR			Q8NBH2	KY_HUMAN	kyphoscoliosis peptidase	432						cytoskeleton|Z disc	peptidase activity			central_nervous_system(1)|endometrium(3)|kidney(1)|lung(12)|ovary(2)|upper_aerodigestive_tract(2)	21						TGCACTTGAGCGTGTACTCCA	0.567000													11	27					0	0	1	0	0
LOC645752	645752	broad.mit.edu	37	15	78212618	78212618	+	RNA	SNP	A	A	G			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr15:78212618A>G	ENST00000565869.1	+	0	111				RP11-114H24.2_ENST00000567226.1_RNA																							TGTAACCGCCACTGGAGGACC	0.562000													4	36					0	0	1	0	0
NEDD4	4734	broad.mit.edu	37	15	56208601	56208601	+	Missense_Mutation	SNP	A	A	C			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr15:56208601A>C	ENST00000508342.1	-	1	728	c.429T>G	c.(427-429)agT>agG	p.S143R	NEDD4_ENST00000506154.1_Missense_Mutation_p.S143R|NEDD4_ENST00000435532.3_Intron|NEDD4_ENST00000338963.2_Missense_Mutation_p.S143R	NM_001284338.1	NP_001271267.1	P46934	NEDD4_HUMAN	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	143	Ser-rich.				development involved in symbiotic interaction|glucocorticoid receptor signaling pathway|negative regulation of sodium ion transport|negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage|negative regulation of vascular endothelial growth factor receptor signaling pathway|neuron projection development|positive regulation of nucleocytoplasmic transport|positive regulation of phosphatidylinositol 3-kinase cascade|positive regulation of protein catabolic process|progesterone receptor signaling pathway|protein K63-linked ubiquitination|protein targeting to lysosome|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|receptor catabolic process|receptor internalization|regulation of dendrite morphogenesis|response to calcium ion|transmission of virus	apicolateral plasma membrane|cell cortex|chromatin|cytosol|perinuclear region of cytoplasm|ubiquitin ligase complex	beta-2 adrenergic receptor binding|phosphoserine binding|phosphothreonine binding|proline-rich region binding|protein domain specific binding|RNA polymerase binding|sodium channel inhibitor activity|ubiquitin binding|ubiquitin-protein ligase activity			breast(1)|endometrium(3)|kidney(3)|large_intestine(10)|lung(15)|ovary(1)|prostate(1)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	43				all cancers(107;0.0299)|GBM - Glioblastoma multiforme(80;0.113)		AAATGGCTGGACTGCTTACAA	0.408000													74	88					0	0	1	0	0
LINC00303	284573	broad.mit.edu	37	1	204006301	204006301	+	RNA	SNP	G	G	T			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr1:204006301G>T	ENST00000367207.3	-	0	719																											CCTTCTCAGGGCCTTGCCCCT	0.512000													4	9					1	1	1	1	0
IDH1	3417	broad.mit.edu	37	2	209113113	209113113	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr2:209113113G>A	ENST00000415913.1	-	4	775	c.394C>T	c.(394-396)Cgt>Tgt	p.R132C	IDH1_ENST00000345146.2_Missense_Mutation_p.R132C|IDH1_ENST00000446179.1_Missense_Mutation_p.R132C	NM_001282387.1	NP_001269316.1	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132			R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).|R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132C(446)|p.R132G(125)|p.R132S(106)|p.G131_R132>VL(1)|p.R132V(1)		NS(1)|autonomic_ganglia(2)|biliary_tract(24)|bone(237)|central_nervous_system(3764)|endometrium(3)|haematopoietic_and_lymphoid_tissue(794)|kidney(2)|large_intestine(7)|lung(7)|prostate(6)|skin(5)|soft_tissue(12)|thyroid(22)|urinary_tract(1)	4887				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		TAAGCATGACGACCTATGATG	0.398000			Mis		gliobastoma								30	43					0	0	1	0	0
MEGF11	84465	broad.mit.edu	37	15	66210374	66210374	+	Translation_Start_Site	SNP	G	G	A			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr15:66210374G>A	ENST00000395614.1	-	0	2076				MEGF11_ENST00000395625.2_Silent_p.N597N|MEGF11_ENST00000288745.3_Silent_p.N597N|MEGF11_ENST00000422354.1_Silent_p.N672N|MEGF11_ENST00000360698.4_Silent_p.N672N|MEGF11_ENST00000409699.2_Silent_p.N672N			A6BM72	MEG11_HUMAN	multiple EGF-like-domains 11							basolateral plasma membrane|integral to membrane				breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(4)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	19						TGCAGGTCCCGTTGTTGGCAC	0.612000													14	26					0	0	1	0	0
WDR81	124997	broad.mit.edu	37	17	1633762	1633762	+	Translation_Start_Site	SNP	G	G	A			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr17:1633762G>A	ENST00000545662.1	+	0	8				WDR81_ENST00000409644.1_Silent_p.L1252L|WDR81_ENST00000437219.2_Silent_p.L49L|WDR81_ENST00000419248.1_Silent_p.L25L|RP11-961A15.1_ENST00000576540.1_RNA|WDR81_ENST00000446363.1_Intron|WDR81_ENST00000309182.5_Silent_p.L201L			B3KXU1	B3KXU1_HUMAN	WD repeat domain 81											cervix(1)|endometrium(1)|kidney(3)|lung(6)|ovary(2)|prostate(2)|skin(1)	16				UCEC - Uterine corpus endometrioid carcinoma (25;0.0822)		TGCTCCGCCTGCTGACGTCTT	0.647000													10	13					0	0	1	0	0
WEE2	494551	broad.mit.edu	37	7	141418984	141418984	+	Missense_Mutation	SNP	T	T	C			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr7:141418984T>C	ENST00000397541.2	+	4	1104	c.698T>C	c.(697-699)cTg>cCg	p.L233P	WEE2-AS1_ENST00000495800.1_RNA|WEE2-AS1_ENST00000465110.1_RNA|WEE2-AS1_ENST00000478332.1_RNA|WEE2-AS1_ENST00000488785.1_RNA|WEE2-AS1_ENST00000471512.1_RNA|WEE2-AS1_ENST00000459753.1_RNA|WEE2-AS1_ENST00000462383.1_RNA	NM_001105558.1	NP_001099028.1	P0C1S8	WEE2_HUMAN	WEE1 homolog 2 (S. pombe)	233	Protein kinase.				egg activation|female meiosis|female pronucleus assembly|meiotic metaphase II|meiotic prophase I|mitosis|negative regulation of oocyte development|regulation of meiosis I	centrosome|nucleus	ATP binding|magnesium ion binding|non-membrane spanning protein tyrosine kinase activity|protein serine/threonine kinase activity			breast(1)|central_nervous_system(1)|endometrium(4)|large_intestine(5)|lung(14)|ovary(1)|prostate(2)|skin(2)|stomach(1)	31	Melanoma(164;0.0171)					ATTAAGAGGCTGGATGGATGT	0.363000													50	63					0	0	1	0	0
KIF24	347240	broad.mit.edu	37	9	34306264	34306264	+	Missense_Mutation	SNP	G	G	T			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr9:34306264G>T	ENST00000379166.2	-	3	918	c.799C>A	c.(799-801)Caa>Aaa	p.Q267K	KIF24_ENST00000402558.2_Missense_Mutation_p.Q267K|KIF24_ENST00000345050.2_Missense_Mutation_p.Q267K|KIF24_ENST00000379174.3_Missense_Mutation_p.Q267K	NM_194313.2	NP_919289.2	Q5T7B8	KIF24_HUMAN	kinesin family member 24	267	Kinesin-motor.				microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity			breast(1)|central_nervous_system(1)|endometrium(5)|large_intestine(4)|liver(1)|lung(13)|prostate(3)|skin(1)|stomach(1)|upper_aerodigestive_tract(2)	32			LUSC - Lung squamous cell carcinoma(29;0.0107)			AGAATATATTGAGTGAGGTCA	0.353000													61	89					1.7104e-27	1.80542e-27	1	1	0
PDILT	204474	broad.mit.edu	37	16	20410472	20410472	+	Missense_Mutation	SNP	C	C	T			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr16:20410472C>T	ENST00000302451.4	-	2	399	c.151G>A	c.(151-153)Gct>Act	p.A51T		NM_174924.1	NP_777584.1	Q8N807	PDILT_HUMAN	protein disulfide isomerase-like, testis expressed	51					cell differentiation|cell redox homeostasis|multicellular organismal development|spermatogenesis	endoplasmic reticulum	isomerase activity	p.A51T(1)		breast(2)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(13)|liver(1)|lung(33)|prostate(3)|skin(1)|urinary_tract(1)	61						GTCAGGCCAGCGGGCGTTAGC	0.577000													46	57					0	0	1	0	0
SPDL1	54908	broad.mit.edu	37	5	169015540	169015540	+	Silent	SNP	A	A	G			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr5:169015540A>G	ENST00000265295.4	+	2	399	c.120A>G	c.(118-120)caA>caG	p.Q40Q	SPDL1_ENST00000510751.1_3'UTR	NM_017785.4	NP_060255.3			spindle apparatus coiled-coil protein 1																		TACAGAATCAATTGGATAAAT	0.408000													6	33					0	0	1	0	0
LOC100131564	100131564	broad.mit.edu	37	1	93744310	93744310	+	RNA	DEL	T	T	-			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr1:93744310delT	ENST00000451302.2	-	0	1008				RP4-717I23.3_ENST00000415150.1_RNA|RP4-717I23.3_ENST00000455474.1_RNA|RP4-717I23.3_ENST00000414430.1_RNA|RP4-717I23.3_ENST00000413606.1_RNA|RP4-717I23.3_ENST00000429859.1_RNA|RP4-717I23.3_ENST00000447577.1_RNA|RP4-717I23.3_ENST00000446528.2_RNA|RP4-717I23.3_ENST00000442860.1_RNA|RP4-717I23.3_ENST00000457025.1_RNA|RP4-717I23.3_ENST00000424517.3_RNA|RP4-717I23.3_ENST00000427669.1_RNA																							GGAATGCaaattttttttttt	0.279													2	4	---	---	---	---					
LINC01122	400955	broad.mit.edu	37	2	58687297	58687298	+	RNA	INS	-	-	T	rs142388743	by1000genomes	TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr2:58687297_58687298insT	ENST00000452840.1	+	0	127																											ATCTGTGTTTCTTTTTTTTTTC	0.312													3	3	---	---	---	---					
HLA-V	352962	broad.mit.edu	37	6	29760353	29760373	+	RNA	DEL	GCGGGCGCCGTGGATGGAGCA	GCGGGCGCCGTGGATGGAGCA	-	rs74661005	by1000genomes	TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chr6:29760353_29760373delGCGGGCGCCGTGGATGGAGCA	ENST00000457107.1	+	0	223_243																											GGATGGAGCCGCGGGCGCCGTGGATGGAGCAGGAGGGGCCG	0.674													5	8	---	---	---	---					
ATRX	546	broad.mit.edu	37	X	76938201	76938202	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-VM-A8CH-01A-12D-A36O-08	TCGA-VM-A8CH-10A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	15818586-d771-4a30-ab11-16d2fc88de2f	a34a7eab-90c7-4687-b11c-cac4197ac6e2	g.chrX:76938201_76938202delAG	ENST00000373344.5	-	9	2760_2761	c.2546_2547delCT	c.(2545-2547)tctfs	p.S850fs	ATRX_ENST00000395603.3_Frame_Shift_Del_p.S812fs|ATRX_ENST00000480283.1_5'UTR	NM_000489.3	NP_000480.3	P46100	ATRX_HUMAN	alpha thalassemia/mental retardation syndrome X-linked	850					DNA methylation|DNA recombination|DNA repair|regulation of transcription, DNA-dependent	nuclear heterochromatin	ATP binding|chromo shadow domain binding|DNA binding|DNA helicase activity|zinc ion binding	p.?(1)		bone(1)|breast(6)|central_nervous_system(31)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(15)|kidney(14)|large_intestine(1)|liver(1)|lung(40)|ovary(2)|pancreas(13)|prostate(5)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	145					Phosphatidylserine(DB00144)	CATCTTCAGAAGAGTCAAAATC	0.342			"""Mis, F, N"""		"""Pancreatic neuroendocrine tumors, paediatric GBM"""		ATR-X (alpha thalassemia/mental retardation) syndrome						123	56	---	---	---	---					
