Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PASD1	139135	broad.mit.edu	37	X	150789453	150789453	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:150789453G>A	ENST00000370357.4	+	5	504	c.259G>A	c.(259-261)Gat>Aat	p.D87N		NM_173493.2	NP_775764.2	Q8IV76	PASD1_HUMAN	PAS domain containing 1	87	PAS.					nucleus	signal transducer activity			breast(2)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(3)|liver(1)|lung(25)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	48	Acute lymphoblastic leukemia(192;6.56e-05)					TGAAGAGAAAGATGAAGTCTA	0.388000													86	91					0	0	0.139131	0	0
EIF4G3	8672	broad.mit.edu	37	1	21183973	21183973	+	Nonsense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:21183973C>A	ENST00000602326.1	-	23	3695	c.3112G>T	c.(3112-3114)Gaa>Taa	p.E1038*	EIF4G3_ENST00000536266.1_Nonsense_Mutation_p.E636*|EIF4G3_ENST00000264211.8_Nonsense_Mutation_p.E1032*|EIF4G3_ENST00000537738.1_Nonsense_Mutation_p.E522*|EIF4G3_ENST00000400422.1_Nonsense_Mutation_p.E1032*|EIF4G3_ENST00000374935.3_Nonsense_Mutation_p.E752*|EIF4G3_ENST00000374937.3_Nonsense_Mutation_p.E1038*	NM_001198802.1	NP_001185731.1	O43432	IF4G3_HUMAN	eukaryotic translation initiation factor 4 gamma, 3	1032					interspecies interaction between organisms|regulation of translational initiation|RNA metabolic process	eukaryotic translation initiation factor 4F complex	protein binding|RNA cap binding|translation initiation factor activity			endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(18)|lung(20)|ovary(1)|prostate(4)|skin(3)|stomach(1)|urinary_tract(3)	70		all_lung(284;2.61e-06)|Lung NSC(340;2.81e-06)|Colorectal(325;3.46e-05)|Renal(390;9.67e-05)|Breast(348;0.00149)|Ovarian(437;0.00338)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.023)|COAD - Colon adenocarcinoma(152;5.42e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000327)|GBM - Glioblastoma multiforme(114;0.000696)|Kidney(64;0.0018)|STAD - Stomach adenocarcinoma(196;0.00644)|KIRC - Kidney renal clear cell carcinoma(64;0.0185)|READ - Rectum adenocarcinoma(331;0.124)|Lung(427;0.191)		CACCCACCTTCGTCCACTCTC	0.448000													47	337					2.43139e-17	3.28396e-17	0.139131	1	0
LCTL	197021	broad.mit.edu	37	15	66853627	66853627	+	Nonsense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:66853627C>T	ENST00000341509.5	-	5	638	c.507G>A	c.(505-507)tgG>tgA	p.W169*	LCTL_ENST00000537670.1_5'UTR	NM_207338.2	NP_997221.2	Q6UWM7	LCTL_HUMAN	lactase-like	169					carbohydrate metabolic process	endoplasmic reticulum membrane|integral to membrane	cation binding|hydrolase activity, hydrolyzing O-glycosyl compounds			NS(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(6)|lung(10)|ovary(2)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	32						TCACATTCTGCCACCCACCGT	0.517000													4	83					0	0	0.150653	0	0
DSP	1832	broad.mit.edu	37	6	7572172	7572172	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:7572172G>C	ENST00000379802.3	+	15	2342	c.2001G>C	c.(1999-2001)tgG>tgC	p.W667C	DSP_ENST00000418664.2_Missense_Mutation_p.W667C	NM_004415.2	NP_004406.2	P15924	DESP_HUMAN	desmoplakin	667	Globular 1.				cellular component disassembly involved in apoptosis|keratinocyte differentiation|peptide cross-linking	cornified envelope|cytoplasm|desmosome	protein binding, bridging|structural constituent of cytoskeleton			biliary_tract(1)|breast(6)|central_nervous_system(7)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(16)|liver(2)|lung(27)|ovary(4)|prostate(1)|skin(8)|stomach(3)|upper_aerodigestive_tract(7)|urinary_tract(5)	101	Ovarian(93;0.0584)	all_hematologic(90;0.236)		OV - Ovarian serous cystadenocarcinoma(45;0.000508)		AAGAAACATGGATGCTGATGG	0.463000													3	108					0	0	0.115264	0	0
MEST	4232	broad.mit.edu	37	7	130137853	130137853	+	Splice_Site	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:130137853C>T	ENST00000223215.4	+	4	559	c.339_splice	c.e4+1	p.P113_splice	MEST_ENST00000462132.1_3'UTR|MEST_ENST00000378576.4_Splice_Site_p.P104_splice|MEST_ENST00000437945.1_Splice_Site_p.P113_splice|hsa-mir-335_ENST00000604666.1_RNA|MEST_ENST00000416162.2_Splice_Site_p.P104_splice|MEST_ENST00000393187.1_Splice_Site_p.P104_splice|MEST_ENST00000341441.4_Splice_Site_p.P104_splice	NM_001253900.1|NM_002402.3	NP_001240829.1|NP_002393.2	Q5EB52	MEST_HUMAN	mesoderm specific transcript	113					mesoderm development	endoplasmic reticulum membrane|integral to membrane	hydrolase activity|protein binding			breast(1)|endometrium(2)|large_intestine(3)|lung(4)|ovary(2)	12	Melanoma(18;0.0435)					AGTGACAAACCGGTAAGCAGC	0.512000													63	109					0	0	0.139131	0	0
ZDHHC22	283576	broad.mit.edu	37	14	77600032	77600032	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:77600032A>T	ENST00000319374.4	-	3	988	c.786T>A	c.(784-786)gaT>gaA	p.D262E	RP11-463C8.4_ENST00000557752.1_Intron	NM_174976.2	NP_777636.2	Q8N966	ZDH22_HUMAN	zinc finger, DHHC-type containing 22	262						integral to membrane	acyltransferase activity|zinc ion binding			kidney(1)|lung(1)|urinary_tract(1)	3			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0277)		TCTACTACTTATCCTGCTGCT	0.517000													19	16					0	0	0.091800	0	0
SLC13A4	26266	broad.mit.edu	37	7	135392895	135392895	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:135392895C>T	ENST00000354042.4	-	3	1021	c.332G>A	c.(331-333)cGc>cAc	p.R111H	AC091736.10_ENST00000378428.3_RNA	NM_012450.2	NP_036582.2	Q9UKG4	S13A4_HUMAN	solute carrier family 13 (sodium/sulfate symporter), member 4	111						integral to plasma membrane	sodium:sulfate symporter activity			breast(1)|central_nervous_system(2)|endometrium(3)|kidney(2)|large_intestine(6)|lung(7)|skin(1)|upper_aerodigestive_tract(2)	24						CAAGACCATGCGCAGAGCAAT	0.592000													6	236					0	0	0.029380	0	0
ANKRD30BP2	149992	broad.mit.edu	37	21	14414855	14414855	+	RNA	SNP	A	A	G	rs141732548	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr21:14414855A>G	ENST00000507941.1	+	0	95																											GCCAATGGCCATGCAGAAGTA	0.448000													7	42					0	0	0.069234	0	0
TACC2	10579	broad.mit.edu	37	10	123843769	123843769	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:123843769C>T	ENST00000369005.1	+	4	2094	c.1754C>T	c.(1753-1755)cCa>cTa	p.P585L	TACC2_ENST00000358010.1_Intron|TACC2_ENST00000334433.3_Missense_Mutation_p.P585L|TACC2_ENST00000515273.1_Missense_Mutation_p.P585L|TACC2_ENST00000515603.1_Missense_Mutation_p.P585L|TACC2_ENST00000513429.1_Intron|TACC2_ENST00000453444.2_Missense_Mutation_p.P585L	NM_206862.2	NP_996744.2	O95359	TACC2_HUMAN	transforming, acidic coiled-coil containing protein 2	585						microtubule organizing center|nucleus	nuclear hormone receptor binding			NS(1)|breast(5)|central_nervous_system(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(15)|lung(27)|ovary(6)|prostate(3)|skin(8)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(3)	83		all_neural(114;0.0656)|Lung NSC(174;0.136)|all_lung(145;0.17)|Breast(234;0.197)				GCCCCAGAGCCACCTGATGGT	0.557000													13	14					0	0	0.093190	0	0
PABPC3	5042	broad.mit.edu	37	13	25670848	25670848	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:25670848G>T	ENST00000281589.3	+	1	549	c.512G>T	c.(511-513)gGa>gTa	p.G171V		NM_030979.2	NP_112241.2	Q9H361	PABP3_HUMAN	poly(A) binding protein, cytoplasmic 3	171	RRM 2.				mRNA metabolic process	cytoplasm	nucleotide binding|poly(A) RNA binding			breast(1)|cervix(1)|endometrium(3)|kidney(3)|large_intestine(10)|lung(21)|ovary(4)|pancreas(1)|skin(3)	47		Lung SC(185;0.0225)|Breast(139;0.0602)		all cancers(112;0.0071)|Epithelial(112;0.0398)|OV - Ovarian serous cystadenocarcinoma(117;0.151)|GBM - Glioblastoma multiforme(144;0.222)|Lung(94;0.241)		GTATTTGTTGGACAATTTAAG	0.388000													11	56					5.50884e-06	6.58528e-06	0.093190	1	0
SLC5A1	6523	broad.mit.edu	37	22	32500780	32500780	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr22:32500780G>A	ENST00000266088.4	+	14	1923	c.1673G>A	c.(1672-1674)cGt>cAt	p.R558H	SLC5A1_ENST00000543737.1_Missense_Mutation_p.R431H	NM_000343.3	NP_000334.1	P13866	SC5A1_HUMAN	solute carrier family 5 (sodium/glucose cotransporter), member 1	558					carbohydrate metabolic process	integral to plasma membrane	glucose:sodium symporter activity|protein binding			NS(1)|breast(2)|endometrium(3)|kidney(2)|large_intestine(3)|lung(18)|ovary(1)|prostate(2)|skin(4)|urinary_tract(1)	37						CAGCTCTACCGTCTGTGTTGG	0.502000													17	2					0	0	0.204396	0	0
CHM	1121	broad.mit.edu	37	X	85233809	85233809	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:85233809G>T	ENST00000357749.2	-	4	305	c.276C>A	c.(274-276)gaC>gaA	p.D92E	CHM_ENST00000358786.4_Missense_Mutation_p.D92E|CHM_ENST00000537751.1_Intron|CHM_ENST00000467744.1_Intron	NM_000390.2	NP_000381.1	P24386	RAE1_HUMAN	choroideremia (Rab escort protein 1)	92					intracellular protein transport|protein geranylgeranylation|response to stimulus|visual perception	Rab-protein geranylgeranyltransferase complex	GTPase activator activity|Rab geranylgeranyltransferase activity			breast(1)|endometrium(1)|kidney(1)|large_intestine(2)|liver(1)|lung(12)|ovary(1)|prostate(1)	20		all_lung(315;5.41e-06)				GAATAGTTTTGTCCTTCCTGC	0.358000													10	37					4.36969e-10	5.41009e-10	0.105934	1	0
TMEM131	23505	broad.mit.edu	37	2	98451367	98451367	+	Missense_Mutation	SNP	T	T	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:98451367T>C	ENST00000186436.5	-	9	1054	c.826A>G	c.(826-828)Aag>Gag	p.K276E	TMEM131_ENST00000425805.2_Missense_Mutation_p.K227E	NM_015348.1	NP_056163.1	Q92545	TM131_HUMAN	transmembrane protein 131	276						integral to membrane				NS(1)|autonomic_ganglia(1)|breast(3)|central_nervous_system(4)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(23)|ovary(4)|prostate(1)|skin(1)|stomach(1)	57						ATCACTCCCTTGGTTTCATAA	0.373000													57	64					0	0	0.139131	0	0
ITGA2	3673	broad.mit.edu	37	5	52351368	52351368	+	Splice_Site	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:52351368A>G	ENST00000296585.5	+	8	923	c.779_splice	c.e8-1	p.R260_splice		NM_002203.3	NP_002194.2	P17301	ITA2_HUMAN	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	260	VWFA.				axon guidance|blood coagulation|cell-matrix adhesion|integrin-mediated signaling pathway|interspecies interaction between organisms|organ morphogenesis	integrin complex	collagen binding|identical protein binding|receptor activity			breast(3)|central_nervous_system(2)|endometrium(5)|kidney(3)|large_intestine(8)|liver(1)|lung(18)|pancreas(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	47		Lung NSC(810;3.11e-05)|Breast(144;0.014)|Prostate(461;0.0181)				TCTGCCACAGAAAATATGCTT	0.348000													25	7					0	0	0.134883	0	0
PTPRB	5787	broad.mit.edu	37	12	70983978	70983978	+	Missense_Mutation	SNP	T	T	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:70983978T>C	ENST00000334414.6	-	8	1860	c.1816A>G	c.(1816-1818)Aat>Gat	p.N606D	PTPRB_ENST00000538708.1_Missense_Mutation_p.N388D|PTPRB_ENST00000550358.1_Missense_Mutation_p.N606D|PTPRB_ENST00000551525.1_Missense_Mutation_p.N605D|PTPRB_ENST00000550857.1_Intron|PTPRB_ENST00000538174.2_5'UTR|PTPRB_ENST00000451516.2_Intron|PTPRB_ENST00000261266.5_Missense_Mutation_p.N388D	NM_001109754.2	NP_001103224.1	P23467	PTPRB_HUMAN	protein tyrosine phosphatase, receptor type, B	388	Fibronectin type-III 7.				angiogenesis	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity			breast(4)|central_nervous_system(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(8)|lung(46)|prostate(4)|skin(18)|upper_aerodigestive_tract(1)|urinary_tract(3)	107	Renal(347;0.236)		GBM - Glioblastoma multiforme(2;2.17e-05)|Lung(24;0.000636)|OV - Ovarian serous cystadenocarcinoma(12;0.00306)|STAD - Stomach adenocarcinoma(21;0.149)			ATCCTGCCATTATTGTTTGCC	0.448000											OREG0021990	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	75	92					0	0	0.139131	0	0
SLC44A5	204962	broad.mit.edu	37	1	76007131	76007131	+	Translation_Start_Site	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:76007131A>G	ENST00000370855.5	-	2	115	c.2T>C	c.(1-3)aTg>aCg	p.M1T	SLC44A5_ENST00000469525.1_5'UTR|SLC44A5_ENST00000370859.3_Start_Codon_SNP_p.M1T	NM_152697.4	NP_689910.2	Q8NCS7	CTL5_HUMAN	solute carrier family 44, member 5	1						integral to membrane|plasma membrane	choline transmembrane transporter activity			kidney(1)|large_intestine(13)|lung(35)|ovary(2)|prostate(1)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	61						TGTGTCATTCATTGAGATAAA	0.323000													44	12					0	0	0.139131	0	0
RFC5	5985	broad.mit.edu	37	12	118462732	118462732	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:118462732G>T	ENST00000392542.2	+	7	968	c.435G>T	c.(433-435)caG>caT	p.Q145H	RFC5_ENST00000229043.3_Missense_Mutation_p.Q81H|RFC5_ENST00000454402.2_Missense_Mutation_p.Q166H	NM_181578.3	NP_853556.2	P40937	RFC5_HUMAN	replication factor C (activator 1) 5, 36.5kDa	166					cell cycle checkpoint|DNA strand elongation involved in DNA replication|nucleotide-excision repair, DNA gap filling|S phase of mitotic cell cycle|telomere maintenance via recombination|telomere maintenance via semi-conservative replication|transcription-coupled nucleotide-excision repair	DNA replication factor C complex|nucleoplasm	ATP binding|DNA clamp loader activity|enzyme binding			NS(1)|breast(1)|endometrium(1)|large_intestine(3)|lung(3)	9	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					CTGCCTTGCAGTCCCGCTGCA	0.473000													7	62					8.12818e-05	9.60604e-05	0.029380	1	0
DCAF12	25853	broad.mit.edu	37	9	34125044	34125044	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:34125044C>A	ENST00000361264.4	-	2	651	c.310G>T	c.(310-312)Gtg>Ttg	p.V104L	DCAF12_ENST00000463286.1_5'UTR	NM_015397.3	NP_056212.1	Q5T6F0	DCA12_HUMAN	DDB1 and CUL4 associated factor 12	104						centrosome|CUL4 RING ubiquitin ligase complex				breast(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(4)|prostate(1)	11						GTGCCACACACCACTTGCCTA	0.493000													5	56					0.0215528	0.0233488	0.021553	1	0
CLCN3	1182	broad.mit.edu	37	4	170618824	170618824	+	Nonsense_Mutation	SNP	G	G	A	rs67071267		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:170618824G>A	ENST00000513761.1	+	9	2061	c.1502G>A	c.(1501-1503)tGg>tAg	p.W501*	CLCN3_ENST00000360642.3_Nonsense_Mutation_p.W474*|CLCN3_ENST00000347613.4_Nonsense_Mutation_p.W501*|CLCN3_ENST00000504131.2_Nonsense_Mutation_p.W484*	NM_001829.3	NP_001820.2	P51790	CLCN3_HUMAN	chloride channel, voltage-sensitive 3	501					endosomal lumen acidification	cell surface|early endosome membrane|Golgi membrane|integral to membrane|late endosome membrane|transport vesicle membrane	antiporter activity|ATP binding|PDZ domain binding|protein heterodimerization activity|protein homodimerization activity|voltage-gated chloride channel activity			breast(5)|endometrium(3)|large_intestine(8)|lung(8)|ovary(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(1)	29		Prostate(90;0.00601)|Renal(120;0.0183)		GBM - Glioblastoma multiforme(119;0.0233)|LUSC - Lung squamous cell carcinoma(193;0.131)		TCAGCTATATGGCAGTTATGC	0.388000													75	44					0	0	0.139131	0	0
SMG1P7	100506060	broad.mit.edu	37	16	70253871	70253871	+	RNA	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:70253871A>G	ENST00000581050.1	-	0	1619					NR_033959.1																						GTAAAGCTTCACCGAAGAGTG	0.388000													3	45					0	0	0.115264	0	0
WDR49	151790	broad.mit.edu	37	3	167240228	167240228	+	Missense_Mutation	SNP	T	T	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:167240228T>A	ENST00000308378.3	-	12	1898	c.1593A>T	c.(1591-1593)agA>agT	p.R531S	WDR49_ENST00000476376.1_Missense_Mutation_p.R356S|WDR49_ENST00000453925.2_Intron|WDR49_ENST00000479765.1_Intron	NM_178824.3	NP_849146.1	Q8IV35	WDR49_HUMAN	WD repeat domain 49	531										breast(1)|endometrium(1)|kidney(1)|large_intestine(8)|lung(28)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(2)	50						AATTAGTATCTCTTTTAGGAA	0.294000													52	38					0	0	0.139131	0	0
KDM5C	8242	broad.mit.edu	37	X	53239738	53239738	+	Missense_Mutation	SNP	T	T	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:53239738T>C	ENST00000452825.3	-	10	1935	c.1403A>G	c.(1402-1404)tAt>tGt	p.Y468C	KDM5C_ENST00000404049.3_Missense_Mutation_p.Y534C|KDM5C_ENST00000375379.3_Missense_Mutation_p.Y535C|KDM5C_ENST00000375383.3_Missense_Mutation_p.Y494C|KDM5C_ENST00000375401.3_Missense_Mutation_p.Y535C	NM_001146702.1	NP_001140174.1	P41229	KDM5C_HUMAN	lysine (K)-specific demethylase 5C	535	JmjC.				chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|protein binding|zinc ion binding			autonomic_ganglia(1)|breast(4)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(30)|large_intestine(9)|lung(17)|oesophagus(1)|ovary(6)|prostate(1)|salivary_gland(1)|skin(1)|upper_aerodigestive_tract(2)	82						GGGCACCCCATACCAGGTCTT	0.522000			"""N, F, S"""		clear cell renal carcinoma								10	57					0	0	0.069234	0	0
DCBLD1	285761	broad.mit.edu	37	6	117859994	117859994	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:117859994A>G	ENST00000338728.5	+	8	1092	c.972A>G	c.(970-972)atA>atG	p.I324M	DCBLD1_ENST00000296955.8_Missense_Mutation_p.I324M|GOPC_ENST00000467125.1_Intron|DCBLD1_ENST00000368503.4_Intron			Q8N8Z6	DCBD1_HUMAN	discoidin, CUB and LCCL domain containing 1	324	F5/8 type C.				cell adhesion	integral to membrane				breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(15)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	26		all_cancers(87;0.171)		GBM - Glioblastoma multiforme(226;0.0447)|OV - Ovarian serous cystadenocarcinoma(136;0.0921)|all cancers(137;0.125)		AAAAGAAAATAACAGGTGCAG	0.453000													4	15					0	0	0.184627	0	0
BAGE2	85319	broad.mit.edu	37	21	11058340	11058340	+	RNA	SNP	A	A	C	rs28617310	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr21:11058340A>C	ENST00000470054.1	-	0	324									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GGGGTAAAGGAGAGAAATCTC	0.363000													5	121					0	0	0.184627	0	0
PCK1	5105	broad.mit.edu	37	20	56139562	56139562	+	Missense_Mutation	SNP	C	C	T	rs149472972		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr20:56139562C>T	ENST00000319441.4	+	8	1375	c.1211C>T	c.(1210-1212)tCg>tTg	p.S404L	PCK1_ENST00000543666.1_Missense_Mutation_p.S87L|PCK1_ENST00000535860.1_Silent_p.L301L	NM_002591.3	NP_002582.3	P35558	PCKGC_HUMAN	phosphoenolpyruvate carboxykinase 1 (soluble)	404	Substrate binding.				gluconeogenesis|glucose homeostasis|glycerol biosynthetic process from pyruvate|response to insulin stimulus	cytosol|nucleus	carboxylic acid binding|GTP binding|magnesium ion binding|manganese ion binding|phosphoenolpyruvate carboxykinase (GTP) activity			endometrium(2)|kidney(1)|large_intestine(4)|liver(2)|lung(19)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	34	Lung NSC(12;0.000764)|all_lung(29;0.00264)|Melanoma(10;0.242)		BRCA - Breast invasive adenocarcinoma(13;9.88e-12)|Epithelial(14;3.41e-08)|all cancers(14;2.13e-07)			CACCCCAACTCGAGGTTCTGC	0.587000													39	38					0	0	0.098360	0	0
APC	324	broad.mit.edu	37	5	112174160	112174160	+	Nonsense_Mutation	SNP	A	A	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:112174160A>T	ENST00000457016.1	+	16	3249	c.2869A>T	c.(2869-2871)Aag>Tag	p.K957*	APC_ENST00000508376.2_Nonsense_Mutation_p.K957*|APC_ENST00000257430.4_Nonsense_Mutation_p.K957*|CTC-554D6.1_ENST00000520401.1_Intron			P25054	APC_HUMAN	adenomatous polyposis coli	957	Ser-rich.				canonical Wnt receptor signaling pathway|cell adhesion|cell cycle arrest|cell migration|cellular component disassembly involved in apoptosis|cytokinesis after mitosis|mitotic cell cycle spindle assembly checkpoint|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of cyclin-dependent protein kinase activity|negative regulation of microtubule depolymerization|positive regulation of apoptosis|positive regulation of cell migration|positive regulation of pseudopodium assembly|protein complex assembly|regulation of attachment of spindle microtubules to kinetochore|response to DNA damage stimulus|tight junction assembly	adherens junction|APC-Axin-1-beta-catenin complex|Axin-APC-beta-catenin-GSK3B complex|beta-catenin destruction complex|centrosome|cytosol|kinetochore|lamellipodium|lateral plasma membrane|nucleus|ruffle membrane|tight junction	beta-catenin binding|gamma-catenin binding|microtubule plus-end binding|protein kinase binding|protein kinase regulator activity	p.?(1)		NS(7)|adrenal_gland(6)|biliary_tract(5)|bone(6)|breast(29)|central_nervous_system(12)|cervix(2)|endometrium(12)|haematopoietic_and_lymphoid_tissue(6)|kidney(8)|large_intestine(2768)|liver(15)|lung(39)|oesophagus(1)|ovary(12)|pancreas(27)|prostate(15)|salivary_gland(2)|skin(14)|small_intestine(34)|soft_tissue(55)|stomach(136)|thyroid(22)|upper_aerodigestive_tract(8)|urinary_tract(20)	3261		all_cancers(142;3.01e-27)|all_epithelial(76;2.3e-18)|all_hematologic(541;4.32e-09)|Ovarian(225;1.78e-06)|Lung NSC(167;0.000195)|Breast(839;0.000231)|all_lung(232;0.000247)|Colorectal(10;0.000355)|Prostate(80;0.00133)		OV - Ovarian serous cystadenocarcinoma(64;1.09e-113)|Epithelial(69;3.79e-112)|all cancers(49;1.67e-104)|BRCA - Breast invasive adenocarcinoma(61;0.00136)|COAD - Colon adenocarcinoma(37;0.00155)|Colorectal(14;0.00191)		ATTAGAATACAAGAGATCTTC	0.348000		12	"""D, Mis, N, F, S"""		"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""	"""colorectal, pancreatic, desmoid, hepatoblastoma, glioma, other CNS"""			Turcot syndrome;Hereditary Desmoid Disease;Familial Adenomatous Polyposis	TSP Lung(16;0.13)			27	10					0	0	0.108266	0	0
C11orf30	56946	broad.mit.edu	37	11	76248892	76248892	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:76248892A>G	ENST00000529032.1	+	15	2413	c.2413A>G	c.(2413-2415)Atg>Gtg	p.M805V	C11orf30_ENST00000524490.1_Missense_Mutation_p.M721V|C11orf30_ENST00000343878.3_Missense_Mutation_p.M805V|C11orf30_ENST00000525919.1_Missense_Mutation_p.M806V|C11orf30_ENST00000524767.1_Missense_Mutation_p.M820V|C11orf30_ENST00000533248.1_Intron|C11orf30_ENST00000525038.1_Missense_Mutation_p.M820V|C11orf30_ENST00000334736.3_Missense_Mutation_p.M805V			Q7Z589	EMSY_HUMAN	chromosome 11 open reading frame 30	805					chromatin modification|DNA repair|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus				NS(1)|breast(4)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(10)|liver(1)|lung(23)|ovary(5)|prostate(2)|skin(4)|stomach(1)|urinary_tract(2)	60						CCTGAGTCAAATGGCAGTGCC	0.388000													30	32					0	0	0.144211	0	0
GSN	2934	broad.mit.edu	37	9	124088878	124088878	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:124088878G>A	ENST00000373823.3	+	20	2410	c.1505G>A	c.(1504-1506)cGc>cAc	p.R502H	GSN_ENST00000341272.2_Missense_Mutation_p.R502H|GSN_ENST00000545652.1_Missense_Mutation_p.R510H|GSN_ENST00000436847.1_Missense_Mutation_p.R513H|GSN_ENST00000394353.2_Missense_Mutation_p.R513H|GSN_ENST00000373806.1_5'UTR|GSN_ENST00000412819.1_Missense_Mutation_p.R502H|GSN_ENST00000373818.4_Missense_Mutation_p.R553H|GSN_ENST00000449733.1_Missense_Mutation_p.R502H|GSN_ENST00000373808.2_Missense_Mutation_p.R502H|GSN_ENST00000373807.1_Missense_Mutation_p.R284H			P06396	GELS_HUMAN	gelsolin	553	Actin-binding, Ca-sensitive (Potential).				actin filament polymerization|actin filament severing|barbed-end actin filament capping|cellular component disassembly involved in apoptosis|cilium morphogenesis	actin cytoskeleton|cytosol	actin binding|calcium ion binding|protein binding			NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(6)|kidney(1)|large_intestine(1)|lung(8)|ovary(1)	21						GGCACCTCCCGCGAGGGCGGG	0.662000													6	7					0	0	0.029380	0	0
DCAF8L1	139425	broad.mit.edu	37	X	27998441	27998441	+	Silent	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:27998441C>A	ENST00000441525.1	-	1	1125	c.1011G>T	c.(1009-1011)ctG>ctT	p.L337L		NM_001017930.1	NP_001017930.1	A6NGE4	DC8L1_HUMAN	DDB1 and CUL4 associated factor 8-like 1	337										NS(1)|breast(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(10)|lung(24)|ovary(3)|prostate(1)|skin(4)|stomach(1)|urinary_tract(1)	56						AGATTGTATACAGTCCGACTT	0.413000													14	54					1.5842e-08	1.93832e-08	0.105934	1	0
NTRK3	4916	broad.mit.edu	37	15	88420187	88420187	+	Silent	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:88420187G>T	ENST00000394480.1	-	19	2778	c.2457C>A	c.(2455-2457)atC>atA	p.I819I	NTRK3_ENST00000557856.1_Silent_p.I811I|NTRK3_ENST00000355254.2_Silent_p.I819I|NTRK3_ENST00000357724.2_Silent_p.I825I|NTRK3_ENST00000360948.2_Silent_p.I833I	NM_001243101.1|NM_002530.3	NP_001230030.1|NP_002521.2	Q16288	NTRK3_HUMAN	neurotrophic tyrosine kinase, receptor, type 3	833	Protein kinase.				transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	ATP binding|transmembrane receptor protein tyrosine kinase activity		ETV6/NTRK3(238)	breast(3)|central_nervous_system(3)|endometrium(6)|kidney(1)|large_intestine(22)|lung(63)|ovary(6)|pancreas(3)|prostate(1)|skin(4)|stomach(5)|upper_aerodigestive_tract(2)	119			BRCA - Breast invasive adenocarcinoma(143;0.211)			TGTCCAGGTAGATTGGGGTGG	0.537000			T	ETV6	"""congenital fibrosarcoma, Secretory breast """					TSP Lung(13;0.10)			31	41					1.07121e-22	1.50548e-22	0.092188	1	0
AP4S1	11154	broad.mit.edu	37	14	31549850	31549850	+	Splice_Site	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:31549850G>T	ENST00000216366.4	+	5	574	c.366_splice	c.e5+1	p.Q122_splice	AP4S1_ENST00000542754.2_Intron|AP4S1_ENST00000554609.1_Intron|AP4S1_ENST00000554345.1_Intron|AP4S1_ENST00000313566.6_Intron|AP4S1_ENST00000334725.4_Splice_Site_p.Q122_splice	NM_007077.4	NP_009008.2	Q9Y587	AP4S1_HUMAN	adaptor-related protein complex 4, sigma 1 subunit	20						coated pit|Golgi apparatus	protein transporter activity			lung(1)	1	Hepatocellular(127;0.0877)|Breast(36;0.176)		LUAD - Lung adenocarcinoma(48;0.00292)|Lung(238;0.0164)|BRCA - Breast invasive adenocarcinoma(188;0.221)	GBM - Glioblastoma multiforme(265;0.00553)		GTCCTTATCAGGTAAGTACCA	0.428000													3	26					0.150653	0.161525	0.150653	1	0
ZNF107	51427	broad.mit.edu	37	7	64168663	64168663	+	Nonsense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:64168663G>T	ENST00000395391.1	+	4	3356	c.1981G>T	c.(1981-1983)Gag>Tag	p.E661*	ZNF107_ENST00000344930.3_Nonsense_Mutation_p.E661*|ZNF107_ENST00000423627.1_Nonsense_Mutation_p.E661*			Q9UII5	ZN107_HUMAN	zinc finger protein 107	661					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|central_nervous_system(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(10)|lung(18)|ovary(1)|stomach(1)	37		Lung NSC(55;0.00948)|all_lung(88;0.0249)				TCATACTGGAGAGAAACCTTA	0.378000													5	65					0.00116845	0.00130665	0.021553	1	0
MET	4233	broad.mit.edu	37	7	116397814	116397814	+	Silent	SNP	A	A	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:116397814A>T	ENST00000397752.3	+	8	2288	c.2088A>T	c.(2086-2088)acA>acT	p.T696T	MET_ENST00000318493.6_Silent_p.T696T|MET_ENST00000436117.2_Silent_p.T696T	NM_000245.2|NM_001127500.1	NP_000236.2|NP_001120972.1	P08581	MET_HUMAN	met proto-oncogene	696	IPT/TIG 2.				axon guidance|cell proliferation	basal plasma membrane|integral to plasma membrane	ATP binding|hepatocyte growth factor receptor activity|protein binding			NS(10)|breast(4)|central_nervous_system(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(5)|kidney(25)|large_intestine(8)|liver(3)|lung(70)|ovary(10)|pleura(2)|prostate(4)|skin(5)|stomach(6)|testis(1)|thyroid(4)|upper_aerodigestive_tract(64)|urinary_tract(3)	233	all_cancers(3;1.25e-07)|all_epithelial(6;4.07e-08)|Lung NSC(10;0.00108)|all_lung(10;0.00125)	Ovarian(593;0.133)	GBM - Glioblastoma multiforme(2;2.31e-07)|all cancers(2;0.000419)|STAD - Stomach adenocarcinoma(10;0.000512)			GTGGAAAAACATGTACTTTAA	0.333000			Mis		"""papillary renal, head-neck squamous cell """	papillary renal			Hereditary Papillary Renal Carcinoma (type 1)				38	67					0	0	0.104719	0	0
PARG	8505	broad.mit.edu	37	10	51093329	51093329	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:51093329C>T	ENST00000402038.3	-	4	294	c.295G>A	c.(295-297)Gca>Aca	p.A99T		NM_003631.2	NP_003622.2	Q86W56	PARG_HUMAN	poly (ADP-ribose) glycohydrolase	584					carbohydrate metabolic process	nucleus	poly(ADP-ribose) glycohydrolase activity	p.A584T(1)		endometrium(5)|kidney(2)|lung(1)|ovary(2)	10				Epithelial(53;0.213)		TGAGCTTCTGCTTCTTCAAGT	0.318000													5	129					0	0	0.184627	0	0
GPR112	139378	broad.mit.edu	37	X	135429458	135429458	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:135429458C>A	ENST00000394143.1	+	6	3884	c.3593C>A	c.(3592-3594)gCc>gAc	p.A1198D	GPR112_ENST00000394141.1_Missense_Mutation_p.A993D|GPR112_ENST00000370652.1_Missense_Mutation_p.A1198D|GPR112_ENST00000287534.4_Missense_Mutation_p.A1135D|GPR112_ENST00000412101.1_Missense_Mutation_p.A993D	NM_153834.3	NP_722576.3	Q8IZF6	GP112_HUMAN	G protein-coupled receptor 112	1198					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(2)|breast(13)|central_nervous_system(2)|cervix(3)|endometrium(17)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(33)|lung(97)|ovary(5)|pancreas(2)|prostate(4)|skin(10)|upper_aerodigestive_tract(1)|urinary_tract(2)	199	Acute lymphoblastic leukemia(192;0.000127)					GGAGTTGTTGCCAGCTTGGCT	0.463000													82	214					1.71537e-69	2.51266e-69	0.139131	1	0
POM121L12	285877	broad.mit.edu	37	7	53104228	53104228	+	Silent	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:53104228C>T	ENST00000408890.4	+	1	880	c.864C>T	c.(862-864)acC>acT	p.T288T		NM_182595.3	NP_872401.3	Q8N7R1	P1L12_HUMAN	POM121 transmembrane nucleoporin-like 12	288										endometrium(5)|kidney(1)|large_intestine(5)|lung(44)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)	61						TCGAGGTCACCCAGTCTGCTG	0.612000													26	40					0	0	0.116897	0	0
MAGEA1	4100	broad.mit.edu	37	X	152482654	152482654	+	Silent	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:152482654G>T	ENST00000356661.5	-	3	575	c.357C>A	c.(355-357)gcC>gcA	p.A119A		NM_004988.4	NP_004979.3	P43355	MAGA1_HUMAN	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	119	MAGE.					cytoplasm|plasma membrane				breast(1)|central_nervous_system(7)|kidney(2)|lung(6)|ovary(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	19	all_hematologic(71;4.25e-06)|Acute lymphoblastic leukemia(192;6.56e-05)					CTGGCTCCCTGGCTCGATATT	0.488000													17	45					0.000958276	0.00109517	0.189662	1	0
MCF2L	23263	broad.mit.edu	37	13	113728838	113728838	+	Silent	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:113728838C>T	ENST00000397030.1	+	10	1213	c.1176C>T	c.(1174-1176)caC>caT	p.H392H	MCF2L_ENST00000421756.1_Silent_p.H363H|MCF2L_ENST00000442652.2_Silent_p.H389H|MCF2L_ENST00000434480.2_Silent_p.H365H|MCF2L_ENST00000375604.2_Silent_p.H416H|MCF2L_ENST00000423482.2_Silent_p.H357H|MCF2L_ENST00000375601.3_Silent_p.H363H|MCF2L_ENST00000375597.4_Silent_p.H357H|MCF2L_ENST00000535094.2_Silent_p.H359H|MCF2L_ENST00000375608.3_Silent_p.H389H			O15068	MCF2L_HUMAN	MCF.2 cell line derived transforming sequence-like	389					apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|plasma membrane	Rho guanyl-nucleotide exchange factor activity			kidney(1)|large_intestine(5)|ovary(1)|stomach(1)	8	all_lung(23;0.000374)|Lung NSC(43;0.0107)|Lung SC(71;0.0753)|all_neural(89;0.0804)|Hepatocellular(20;0.0877)|Medulloblastoma(90;0.163)	all_cancers(25;0.118)|all_lung(25;0.0368)|all_epithelial(44;0.0396)|Lung NSC(25;0.129)|Breast(118;0.188)				ATGTGGAGCACCTGCTGAGGG	0.627000													17	10					0	0	0.204396	0	0
IL2RG	3561	broad.mit.edu	37	X	70331304	70331304	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:70331304G>A	ENST00000374202.2	-	1	177	c.86C>T	c.(85-87)aCg>aTg	p.T29M		NM_000206.2	NP_000197.1	P31785	IL2RG_HUMAN	interleukin 2 receptor, gamma	29					immune response|interleukin-4-mediated signaling pathway|interspecies interaction between organisms	external side of plasma membrane|integral to plasma membrane	cytokine receptor activity|interleukin-2 binding			breast(1)|endometrium(3)|large_intestine(1)|lung(7)|pancreas(1)|prostate(1)|urinary_tract(1)	15	Renal(35;0.156)				Aldesleukin(DB00041)|Denileukin diftitox(DB00004)	CCCATTGGGCGTCAGAATTGT	0.562000									Severe Combined Immunodeficiency, X-linked				7	75					0	0	0.038147	0	0
KIAA1109	84162	broad.mit.edu	37	4	123192676	123192676	+	Nonsense_Mutation	SNP	C	C	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:123192676C>G	ENST00000264501.4	+	47	8370	c.7997C>G	c.(7996-7998)tCa>tGa	p.S2666*	KIAA1109_ENST00000455637.1_Nonsense_Mutation_p.S2666*|KIAA1109_ENST00000388738.3_Nonsense_Mutation_p.S2666*			Q2LD37	K1109_HUMAN	KIAA1109	2666					regulation of cell growth|regulation of epithelial cell differentiation	integral to membrane|nucleus				breast(7)|central_nervous_system(1)|cervix(1)|endometrium(16)|kidney(6)|large_intestine(33)|liver(4)|lung(74)|ovary(9)|pancreas(1)|prostate(5)|skin(6)|upper_aerodigestive_tract(6)|urinary_tract(3)	172						AGAAGAACATCAAAAGTGTCT	0.348000													15	35					0	0	0.119110	0	0
SLC25A36	55186	broad.mit.edu	37	3	140692807	140692807	+	Silent	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:140692807C>T	ENST00000446041.2	+	6	927	c.702C>T	c.(700-702)gcC>gcT	p.A234A	SLC25A36_ENST00000324194.6_Silent_p.A234A|SLC25A36_ENST00000453248.2_Silent_p.A208A	NM_001104647.1|NM_018155.2	NP_001098117.1|NP_060625.2	Q96CQ1	S2536_HUMAN	solute carrier family 25 (pyrimidine nucleotide carrier ), member 36	234					response to estradiol stimulus|transmembrane transport	integral to membrane|mitochondrial inner membrane	binding			endometrium(2)|large_intestine(2)|lung(1)|upper_aerodigestive_tract(1)	6						TAGCTGCTGCCACCTCAAAAA	0.383000													25	34					0	0	0.116897	0	0
SRP68	6730	broad.mit.edu	37	17	74035838	74035838	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:74035838G>A	ENST00000307877.2	-	16	1994	c.1833C>T	c.(1831-1833)acC>acT	p.T611T	SRP68_ENST00000602720.1_Silent_p.T272T|SRP68_ENST00000539137.1_Silent_p.T573T|SRP68_ENST00000355113.5_Silent_p.T510T|SRP68_ENST00000542536.2_5'UTR	NM_014230.3	NP_055045.2	Q9UHB9	SRP68_HUMAN	signal recognition particle 68kDa	611					response to drug	cytosol|endoplasmic reticulum|nucleolus|ribosome|signal recognition particle, endoplasmic reticulum targeting	RNA binding|signal recognition particle binding			NS(1)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(5)|lung(4)|ovary(2)|prostate(3)	23						GGCCACTCTTGGTCTTCTGTT	0.532000													8	9					0	0	0.038147	0	0
ZDHHC9	51114	broad.mit.edu	37	X	128946792	128946792	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:128946792G>C	ENST00000357166.6	-	8	1070	c.679C>G	c.(679-681)Cta>Gta	p.L227V	ZDHHC9_ENST00000371064.3_Missense_Mutation_p.L227V	NM_016032.3	NP_057116.2	Q9Y397	ZDHC9_HUMAN	zinc finger, DHHC-type containing 9	227						endoplasmic reticulum membrane|Golgi membrane|integral to membrane	acyltransferase activity|zinc ion binding			breast(1)|cervix(1)|endometrium(1)|kidney(3)|large_intestine(3)|lung(8)|ovary(1)|pancreas(1)	19						AGGACTTCTAGAACAGTGAGG	0.473000													35	102					0	0	0.203993	0	0
ABCA8	10351	broad.mit.edu	37	17	66917630	66917630	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:66917630A>G	ENST00000269080.2	-	12	1642	c.1505T>C	c.(1504-1506)cTg>cCg	p.L502P	ABCA8_ENST00000430352.2_Missense_Mutation_p.L502P|ABCA8_ENST00000586539.1_Missense_Mutation_p.L502P	NM_007168.2	NP_009099.1	O94911	ABCA8_HUMAN	ATP-binding cassette, sub-family A (ABC1), member 8	502	ABC transporter 1.					integral to membrane|plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of substances			breast(3)|central_nervous_system(2)|endometrium(9)|kidney(5)|large_intestine(19)|liver(1)|lung(30)|ovary(3)|pancreas(2)|prostate(2)|skin(3)|urinary_tract(4)	83	Breast(10;4.56e-13)					GTCAAATACCAGATCTAGGAA	0.363000													33	34					0	0	0.183431	0	0
NUP214	8021	broad.mit.edu	37	9	134077060	134077060	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:134077060G>A	ENST00000359428.5	+	30	5692	c.5548G>A	c.(5548-5550)Gtg>Atg	p.V1850M	NUP214_ENST00000451030.1_Missense_Mutation_p.V1851M|NUP214_ENST00000483497.2_Missense_Mutation_p.V676M|NUP214_ENST00000411637.2_Missense_Mutation_p.V1840M			P35658	NU214_HUMAN	nucleoporin 214kDa	1850	11 X 3 AA approximate repeats.|11 X 5 AA approximate repeats.|18 X 4 AA approximate repeats.|Pro/Ser/Thr-rich.				carbohydrate metabolic process|glucose transport|mRNA metabolic process|protein export from nucleus|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|nuclear pore|nucleoplasm	protein binding			NS(1)|breast(9)|central_nervous_system(3)|endometrium(13)|kidney(2)|large_intestine(9)|liver(2)|lung(29)|ovary(2)|prostate(3)|skin(7)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	86	all_hematologic(7;0.0028)	Myeloproliferative disorder(178;0.204)		OV - Ovarian serous cystadenocarcinoma(145;3.42e-05)|Epithelial(140;0.000256)		TACTGGTTCTGTGTTTGGTCA	0.348000			T	"""DEK, SET, ABL1"""	"""AML, T-ALL"""								7	15					0	0	0.029380	0	0
EYA1	2138	broad.mit.edu	37	8	72234494	72234494	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:72234494C>T	ENST00000340726.3	-	5	851	c.212G>A	c.(211-213)aGc>aAc	p.S71N	EYA1_ENST00000388741.2_Missense_Mutation_p.S38N|EYA1_ENST00000388740.3_Missense_Mutation_p.S38N|EYA1_ENST00000419131.1_Missense_Mutation_p.S71N|EYA1_ENST00000303824.7_Missense_Mutation_p.S71N|EYA1_ENST00000388743.2_Missense_Mutation_p.S71N|EYA1_ENST00000388742.4_Missense_Mutation_p.S71N	NM_000503.4	NP_000494.2	Q99502	EYA1_HUMAN	eyes absent homolog 1 (Drosophila)	71					double-strand break repair|histone dephosphorylation|positive regulation of DNA repair|protein sumoylation|regulation of transcription, DNA-dependent|response to ionizing radiation|sensory perception of sound|transcription, DNA-dependent	cytoplasm|nucleus	metal ion binding|protein tyrosine phosphatase activity			NS(2)|breast(3)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(8)|lung(15)|ovary(4)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	44	Breast(64;0.046)		Epithelial(68;0.0837)|all cancers(69;0.247)			GAAACTACTGCTCCCAATTGC	0.348000													49	56					0	0	0.139131	0	0
SLC4A10	57282	broad.mit.edu	37	2	162751304	162751304	+	Nonsense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:162751304G>T	ENST00000535165.1	+	10	1343	c.1222G>T	c.(1222-1224)Gaa>Taa	p.E408*	SLC4A10_ENST00000493021.1_3'UTR|SLC4A10_ENST00000421911.1_Missense_Mutation_p.R437L|SLC4A10_ENST00000375514.5_Missense_Mutation_p.R418L|SLC4A10_ENST00000446997.1_Missense_Mutation_p.R437L|SLC4A10_ENST00000272716.5_Missense_Mutation_p.R407L|SLC4A10_ENST00000415876.2_Missense_Mutation_p.R407L			Q6U841	S4A10_HUMAN	solute carrier family 4, sodium bicarbonate transporter, member 10	0					bicarbonate transport|chloride transport|sodium ion transport	integral to membrane|plasma membrane	inorganic anion exchanger activity|symporter activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(9)|lung(35)|ovary(2)|pancreas(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	60						CCAAGCATTCGAATAGAGCCT	0.353000													31	177					4.62619e-21	6.41498e-21	0.203993	1	0
F8	2157	broad.mit.edu	37	X	154159070	154159070	+	Nonsense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:154159070C>A	ENST00000360256.4	-	14	3195	c.2995G>T	c.(2995-2997)Gga>Tga	p.G999*		NM_000132.3	NP_000123.1	P00451	FA8_HUMAN	coagulation factor VIII, procoagulant component	999	B.				acute-phase response|blood coagulation, intrinsic pathway|cell adhesion|platelet activation|platelet degranulation	extracellular space|plasma membrane|platelet alpha granule lumen	copper ion binding|oxidoreductase activity|protein binding			NS(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(3)|kidney(6)|large_intestine(27)|liver(1)|lung(47)|ovary(5)|pancreas(3)|prostate(1)|skin(5)|upper_aerodigestive_tract(5)|urinary_tract(2)	120	all_cancers(53;7.19e-17)|all_epithelial(53;9.83e-11)|all_lung(58;6.63e-07)|Lung NSC(58;2.08e-06)|all_hematologic(71;2.45e-06)|Acute lymphoblastic leukemia(192;6.56e-05)|Breast(217;0.176)|Renal(33;0.214)				Antihemophilic Factor(DB00025)|Coagulation Factor IX(DB00100)|Drotrecogin alfa(DB00055)	AAAGCAGGTCCATGAGCTCTT	0.343000													22	60					1.66031e-10	2.10575e-10	0.091800	1	0
SUCLG1	8802	broad.mit.edu	37	2	84670519	84670519	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:84670519G>A	ENST00000393868.2	-	3	417	c.207C>T	c.(205-207)acC>acT	p.T69T		NM_003849.3	NP_003840.2	P53597	SUCA_HUMAN	succinate-CoA ligase, alpha subunit	69					tricarboxylic acid cycle		ATP citrate synthase activity|GTP binding|succinate-CoA ligase (GDP-forming) activity			kidney(4)|large_intestine(4)|lung(2)	10					Succinic acid(DB00139)	GGCTGTGAAAGGTGCCCTGAG	0.468000													5	49					0	0	0.021553	0	0
GCKR	2646	broad.mit.edu	37	2	27746251	27746251	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:27746251C>T	ENST00000264717.2	+	19	1886	c.1823C>T	c.(1822-1824)cCa>cTa	p.P608L	GCKR_ENST00000424318.2_Missense_Mutation_p.P418L	NM_001486.3	NP_001477.2	Q14397	GCKR_HUMAN	glucokinase (hexokinase 4) regulator	608					carbohydrate metabolic process|glucose transport|negative regulation of glucokinase activity|positive regulation of gene expression|protein import into nucleus, translocation|regulation of glucose transport|response to fructose stimulus|transmembrane transport|triglyceride homeostasis|urate metabolic process	cytosol|nucleoplasm	fructose-6-phosphate binding|protein binding	p.P608L(1)		breast(2)|endometrium(4)|kidney(2)|large_intestine(4)|liver(2)|lung(13)|ovary(2)	29	Acute lymphoblastic leukemia(172;0.155)					CTTGCTGGGCCAGGTCAGAAG	0.602000													23	33					0	0	0.069288	0	0
CSMD1	64478	broad.mit.edu	37	8	3245077	3245077	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:3245077G>A	ENST00000602557.1	-	19	3279	c.2724C>T	c.(2722-2724)gaC>gaT	p.D908D	CSMD1_ENST00000602723.1_Silent_p.D908D|CSMD1_ENST00000520002.1_Silent_p.D908D|CSMD1_ENST00000542608.1_Silent_p.D907D|CSMD1_ENST00000400186.3_Silent_p.D908D|CSMD1_ENST00000539096.1_Silent_p.D907D|CSMD1_ENST00000537824.1_Silent_p.D907D			Q96PZ7	CSMD1_HUMAN	CUB and Sushi multiple domains 1	908	Sushi 5.					integral to membrane				breast(20)|large_intestine(5)	25		all_cancers(1;5.7e-41)|all_epithelial(1;2.54e-36)|Lung NSC(1;7.54e-11)|all_lung(1;3.2e-10)|Hepatocellular(1;3.78e-05)|Breast(1;0.000196)|Myeloproliferative disorder(4;0.000374)|Esophageal squamous(1;0.0157)|Ovarian(12;0.091)|Renal(68;0.144)|Colorectal(14;0.234)		all cancers(1;5.03e-41)|Epithelial(1;4.78e-31)|Lung(1;1.14e-14)|LUSC - Lung squamous cell carcinoma(1;2.34e-14)|GBM - Glioblastoma multiforme(1;4.49e-10)|Colorectal(4;1.18e-07)|OV - Ovarian serous cystadenocarcinoma(1;3.2e-07)|BRCA - Breast invasive adenocarcinoma(1;6.17e-07)|COAD - Colon adenocarcinoma(4;0.000539)|READ - Rectum adenocarcinoma(4;0.00896)|Kidney(5;0.00957)|KIRC - Kidney renal clear cell carcinoma(5;0.0689)		GGGGCTCGTCGTCACTTAGTG	0.607000													4	7					0	0	0.184627	0	0
ST18	9705	broad.mit.edu	37	8	53071600	53071600	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:53071600G>T	ENST00000276480.7	-	15	2347	c.1664C>A	c.(1663-1665)cCt>cAt	p.P555H		NM_014682.2	NP_055497.1	O60284	ST18_HUMAN	suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)	555						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(1)|breast(2)|cervix(1)|endometrium(3)|kidney(3)|large_intestine(14)|lung(38)|ovary(4)|prostate(2)|skin(11)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	85		Lung NSC(129;0.131)|all_epithelial(80;0.217)|all_lung(136;0.229)				GGCACGGCCAGGGCTCTGGGT	0.517000													26	30					8.24728e-16	1.09964e-15	0.099896	1	0
C10orf11	83938	broad.mit.edu	37	10	77542781	77542781	+	Splice_Site	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:77542781G>T	ENST00000372499.1	+	1	262		c.e1+1		C10orf11_ENST00000593699.1_Intron	NM_032024.3	NP_114413.1	Q9H2I8	CJ011_HUMAN	chromosome 10 open reading frame 11											endometrium(1)|large_intestine(4)|lung(4)|stomach(1)	10	Prostate(51;0.0095)|all_epithelial(25;0.0221)					CAAATAAAAGGTTAGCCAGAC	0.408000													5	60					0.00198382	0.00219486	0.029380	1	0
HSFY1P1	27437	broad.mit.edu	37	22	17309768	17309768	+	RNA	SNP	A	A	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr22:17309768A>C	ENST00000425038.1	+	0	924					NR_003607.1																						AACAAATTACAACAAATCAAC	0.393000													10	4					0	0	0.069234	0	0
ADAMTS20	80070	broad.mit.edu	37	12	43858449	43858449	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:43858449C>A	ENST00000389420.3	-	10	1453	c.1454G>T	c.(1453-1455)gGa>gTa	p.G485V	ADAMTS20_ENST00000553158.1_Missense_Mutation_p.G485V	NM_025003.3	NP_079279.3	P59510	ATS20_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 20	485	Disintegrin.					proteinaceous extracellular matrix	zinc ion binding			breast(1)|central_nervous_system(6)|endometrium(3)|kidney(4)|large_intestine(11)|liver(1)|lung(43)|ovary(4)|pancreas(3)|prostate(5)|skin(12)|upper_aerodigestive_tract(1)|urinary_tract(1)	95	all_cancers(12;2.6e-05)|Lung SC(27;0.184)	Lung NSC(34;0.0569)|all_lung(34;0.129)		GBM - Glioblastoma multiforme(48;0.0473)		CTGCTTGTTTCCATCATATCG	0.393000													26	40					8.4185e-14	1.10826e-13	0.163468	1	0
POM121L9P	29774	broad.mit.edu	37	22	24659578	24659578	+	RNA	SNP	A	A	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr22:24659578A>G	ENST00000414583.2	+	0	3103					NR_003714.1																						TGCGCAGGCCAACACTCACTG	0.617000													4	1					0	0	0.184627	0	0
PRB1	5542	broad.mit.edu	37	12	11506932	11506932	+	Missense_Mutation	SNP	A	A	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:11506932A>C	ENST00000500254.2	-	3	142	c.105T>G	c.(103-105)aaT>aaG	p.N35K	PRB1_ENST00000546254.1_Missense_Mutation_p.N35K|PRB1_ENST00000545626.1_Missense_Mutation_p.N35K	NM_005039.3|NM_199353.2	NP_005030.2|NP_955385.1	P04280	PRP1_HUMAN	proline-rich protein BstNI subfamily 1	218						extracellular region				NS(1)|central_nervous_system(1)|kidney(4)|large_intestine(1)|lung(9)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	20			OV - Ovarian serous cystadenocarcinoma(49;0.185)			GTCCTTGTGGATTTCCTGGAG	0.507000													4	369					0	0	0.021553	0	0
HPN	3249	broad.mit.edu	37	19	35540199	35540199	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr19:35540199C>T	ENST00000262626.2	+	3	847	c.22C>T	c.(22-24)Cgg>Tgg	p.R8W	HPN_ENST00000392226.1_Missense_Mutation_p.R8W|HPN_ENST00000597419.1_Intron	NM_182983.2	NP_892028.1	P05981	HEPS_HUMAN	hepsin	8					cell growth|proteolysis	cytoplasm|integral to plasma membrane	scavenger receptor activity|serine-type endopeptidase activity			central_nervous_system(2)|endometrium(3)|kidney(2)|large_intestine(2)|lung(6)|ovary(2)|upper_aerodigestive_tract(2)	19	all_lung(56;5.38e-08)|Lung NSC(56;8.61e-08)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0849)		Coagulation factor VIIa(DB00036)	TGCAGGTGGCCGGACTGTGCC	0.667000													43	45					0	0	0.139131	0	0
IGHG2	3501	broad.mit.edu	37	14	106109853	106109853	+	RNA	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:106109853C>A	ENST00000390545.2	-	0	667																											CTGTGGTTCTCGGGGCTGCCC	0.657000													93	268					6.23493e-48	9.006e-48	0.139131	1	0
DNHD1	144132	broad.mit.edu	37	11	6588872	6588872	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:6588872C>A	ENST00000254579.6	+	36	12697	c.12133C>A	c.(12133-12135)Cgc>Agc	p.R4045S	DNHD1_ENST00000527990.2_Missense_Mutation_p.R4045S	NM_144666.2	NP_653267.2	Q96M86	DNHD1_HUMAN	dynein heavy chain domain 1	4045					microtubule-based movement	dynein complex	microtubule motor activity			NS(1)|autonomic_ganglia(1)|breast(4)|endometrium(13)|kidney(6)|large_intestine(11)|lung(14)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	55		Medulloblastoma(188;0.00776)|all_neural(188;0.0652)|Breast(177;0.171)		Epithelial(150;3.93e-08)|BRCA - Breast invasive adenocarcinoma(625;0.13)		GATCCTGTGGCGCGTTCTGCG	0.627000													17	21					6.49762e-13	8.44691e-13	0.175082	1	0
PJA1	64219	broad.mit.edu	37	X	68381557	68381557	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:68381557C>A	ENST00000361478.1	-	2	1902	c.1525G>T	c.(1525-1527)Gtg>Ttg	p.V509L	PJA1_ENST00000374571.4_Missense_Mutation_p.V454L|PJA1_ENST00000374583.1_Missense_Mutation_p.V509L|PJA1_ENST00000374584.3_Missense_Mutation_p.V321L	NM_001032396.2|NM_022368.4|NM_145119.3	NP_001027568.1|NP_071763.2|NP_660095.1	Q8NG27	PJA1_HUMAN	praja ring finger 1, E3 ubiquitin protein ligase	509							zinc ion binding			endometrium(3)|large_intestine(5)|lung(12)|ovary(1)	21						CTCCAATCCACTTCTAGGTCT	0.478000													10	38					0.000673444	0.000778202	0.069234	1	0
GPLD1	2822	broad.mit.edu	37	6	24436895	24436895	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:24436895C>A	ENST00000230036.1	-	22	2377	c.2267G>T	c.(2266-2268)gGc>gTc	p.G756V		NM_001503.3	NP_001494.2	P80108	PHLD_HUMAN	glycosylphosphatidylinositol specific phospholipase D1	756						extracellular region	glycosylphosphatidylinositol phospholipase D activity			breast(3)|endometrium(5)|kidney(1)|large_intestine(11)|lung(8)|ovary(2)|prostate(1)|urinary_tract(1)	32						ATATACTCGGCCGTCTTCTCC	0.443000													40	25					1.96642e-18	2.69089e-18	0.092188	1	0
EID3	493861	broad.mit.edu	37	12	104698108	104698108	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:104698108G>A	ENST00000527879.1	+	1	592	c.396G>A	c.(394-396)atG>atA	p.M132I	TXNRD1_ENST00000397736.2_Intron|TXNRD1_ENST00000542918.1_Intron|TXNRD1_ENST00000378070.4_Intron|TXNRD1_ENST00000524698.1_Intron|TXNRD1_ENST00000540716.1_Intron|TXNRD1_ENST00000529546.1_Intron|TXNRD1_ENST00000526691.1_Intron|TXNRD1_ENST00000503506.2_Intron|TXNRD1_ENST00000526390.1_Intron|TXNRD1_ENST00000525566.1_Intron|TXNRD1_ENST00000429002.2_Intron|TXNRD1_ENST00000388854.3_Intron|TXNRD1_ENST00000354940.6_Intron	NM_001008394.2	NP_001008395.1	Q8N140	EID3_HUMAN	EP300 interacting inhibitor of differentiation 3	132					regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus				large_intestine(5)|lung(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	10						TGAATTGGATGGAAGGCGATC	0.403000													9	149					0	0	0.058154	0	0
PIP4K2C	79837	broad.mit.edu	37	12	57992982	57992982	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:57992982G>A	ENST00000354947.5	+	5	664	c.648G>A	c.(646-648)aaG>aaA	p.K216K	PIP4K2C_ENST00000422156.3_Silent_p.K168K|PIP4K2C_ENST00000550465.1_Silent_p.K198K|PIP4K2C_ENST00000540759.2_Silent_p.K216K			Q8TBX8	PI42C_HUMAN	phosphatidylinositol-5-phosphate 4-kinase, type II, gamma	216	PIPK.					cytoplasm|membrane	1-phosphatidylinositol-5-phosphate 4-kinase activity|ATP binding|identical protein binding			autonomic_ganglia(1)|breast(3)|central_nervous_system(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(13)|pancreas(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	33	Melanoma(17;0.122)					TGCACAGGAAGTATGACCTCA	0.517000													19	29					0	0	0.055883	0	0
DYNC2H1	79659	broad.mit.edu	37	11	103124071	103124071	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:103124071G>T	ENST00000375735.2	+	66	10244	c.10100G>T	c.(10099-10101)cGc>cTc	p.R3367L	DYNC2H1_ENST00000334267.7_Intron|DYNC2H1_ENST00000398093.3_Missense_Mutation_p.R3374L	NM_001080463.1|NM_001377.2	NP_001073932.1|NP_001368.2	Q8NCM8	DYHC2_HUMAN	dynein, cytoplasmic 2, heavy chain 1	3367	AAA 5 (By similarity).				cell projection organization|Golgi organization|microtubule-based movement|multicellular organismal development	cilium axoneme|dynein complex|Golgi apparatus|microtubule|plasma membrane	ATP binding|ATPase activity|microtubule motor activity			NS(1)|endometrium(4)|kidney(5)|large_intestine(9)|lung(9)|ovary(1)|prostate(2)|upper_aerodigestive_tract(2)	33		Acute lymphoblastic leukemia(157;0.000966)|all_hematologic(158;0.00348)		BRCA - Breast invasive adenocarcinoma(274;0.000177)|Epithelial(105;0.0785)		GAAGAATTCCGCCTCTTTTTG	0.363000													30	31					3.73148e-12	4.79103e-12	0.125774	1	0
MYO3B	140469	broad.mit.edu	37	2	171248925	171248925	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:171248925G>A	ENST00000334231.6	+	16	1738	c.1738G>A	c.(1738-1740)Gac>Aac	p.D580N	MYO3B_ENST00000602629.1_3'UTR|MYO3B_ENST00000408978.4_Missense_Mutation_p.D571N|MYO3B_ENST00000409044.3_Missense_Mutation_p.D571N			Q8WXR4	MYO3B_HUMAN	myosin IIIB	571	Myosin head-like.				response to stimulus|visual perception	cytoplasm|myosin complex	actin binding|ATP binding|motor activity|protein serine/threonine kinase activity	p.D571Y(1)		breast(1)|central_nervous_system(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(25)|ovary(6)|pancreas(1)|prostate(1)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	59						GGTGATGCACGACATAACTTC	0.423000													5	119					0	0	0.184627	0	0
TRIM2	23321	broad.mit.edu	37	4	154191516	154191516	+	Silent	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:154191516C>A	ENST00000338700.5	+	2	125	c.60C>A	c.(58-60)ggC>ggA	p.G20G	TRIM2_ENST00000437508.2_5'UTR|TRIM2_ENST00000494872.1_3'UTR	NM_015271.3	NP_056086.2	Q9C040	TRIM2_HUMAN	tripartite motif containing 2	0						cytoplasm	zinc ion binding	p.G20G(7)		breast(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(5)|lung(7)|prostate(1)	19	all_hematologic(180;0.093)	Medulloblastoma(177;0.00225)		GBM - Glioblastoma multiforme(119;0.0102)|LUSC - Lung squamous cell carcinoma(193;0.0703)		AGACAGCCGGCCCCCCATGTC	0.488000													5	69					0.00116845	0.00130665	0.021553	1	0
MAPK7	5598	broad.mit.edu	37	17	19284751	19284751	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:19284751G>A	ENST00000308406.5	+	4	1615	c.1229G>A	c.(1228-1230)aGt>aAt	p.S410N	MAPK7_ENST00000395604.3_Missense_Mutation_p.S410N|MAPK7_ENST00000395602.4_Missense_Mutation_p.S410N|MAPK7_ENST00000299612.7_Missense_Mutation_p.S271N|MAPK7_ENST00000571657.1_Intron	NM_139033.2	NP_620602.2	Q13164	MK07_HUMAN	mitogen-activated protein kinase 7	410	May not be required for kinase activity; required to stimulate MEF2C activity (By similarity).|Pro-rich.				cell cycle|cell differentiation|innate immune response|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|nerve growth factor receptor signaling pathway|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|nucleoplasm	ATP binding|MAP kinase activity|protein binding			autonomic_ganglia(1)|central_nervous_system(4)|endometrium(5)|kidney(2)|large_intestine(4)|lung(9)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	30	all_cancers(12;2.87e-05)|all_epithelial(12;0.00114)|Hepatocellular(7;0.00345)|Breast(13;0.206)					CCTGTGGCTAGTGAGCCTGGC	0.602000													4	21					0	0	0.021553	0	0
FAM210A	125228	broad.mit.edu	37	18	13681703	13681703	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:13681703C>A	ENST00000322247.3	-	3	761	c.374G>T	c.(373-375)cGa>cTa	p.R125L	FAM210A_ENST00000402563.1_Missense_Mutation_p.R125L|FAM210A_ENST00000588475.1_5'UTR	NM_001098801.1	NP_001092271.1	Q96ND0	CR019_HUMAN	family with sequence similarity 210, member A	125	DUF1279.					integral to membrane		p.R125Q(1)									CTTCTTGAATCGTTGATAAAG	0.393000													9	92					0.000274275	0.000320501	0.047766	1	0
TTC14	151613	broad.mit.edu	37	3	180327571	180327571	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:180327571G>T	ENST00000296015.4	+	12	1686	c.1554G>T	c.(1552-1554)agG>agT	p.R518S	TTC14_ENST00000465625.1_3'UTR|TTC14_ENST00000412756.2_3'UTR|TTC14_ENST00000382584.4_Missense_Mutation_p.R518S	NM_133462.3	NP_597719.1	Q96N46	TTC14_HUMAN	tetratricopeptide repeat domain 14	518	Ser-rich.						RNA binding			endometrium(3)|kidney(5)|large_intestine(9)|lung(24)|ovary(2)|pancreas(1)|skin(1)	45	all_cancers(143;9.31e-15)|Ovarian(172;0.0212)		OV - Ovarian serous cystadenocarcinoma(80;5.62e-23)|GBM - Glioblastoma multiforme(14;0.000558)			GTTCCAGAAGGCATTCATCTA	0.413000													58	62					5.12918e-33	7.30732e-33	0.139131	1	0
CPSF2	53981	broad.mit.edu	37	14	92600468	92600468	+	Missense_Mutation	SNP	T	T	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:92600468T>C	ENST00000298875.4	+	4	548	c.263T>C	c.(262-264)aTt>aCt	p.I88T		NM_017437.2	NP_059133.1	Q9P2I0	CPSF2_HUMAN	cleavage and polyadenylation specific factor 2, 100kDa	88					histone mRNA 3'-end processing|mRNA export from nucleus|nuclear mRNA splicing, via spliceosome|termination of RNA polymerase II transcription	mRNA cleavage and polyadenylation specificity factor complex	hydrolase activity|protein binding|RNA binding			breast(2)|cervix(1)|endometrium(3)|large_intestine(2)|lung(7)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(3)	24		all_cancers(154;0.0766)		COAD - Colon adenocarcinoma(157;0.222)		TATGCAACCATTCCTGTTTAT	0.403000													3	58					0	0	0.150653	0	0
MAGEA12	4111	broad.mit.edu	37	X	151900189	151900189	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:151900189G>A	ENST00000393900.3	-	3	965	c.612C>T	c.(610-612)atC>atT	p.I204I	MAGEA12_ENST00000393869.3_Silent_p.I204I|CSAG4_ENST00000361201.4_RNA|MAGEA12_ENST00000357916.4_Silent_p.I204I	NM_001166386.1	NP_001159858.1	P43365	MAGAC_HUMAN	melanoma antigen family A, 12	204	MAGE.									breast(5)|large_intestine(5)|liver(1)|lung(14)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	28	Acute lymphoblastic leukemia(192;6.56e-05)					TGGCCAGGACGATTATCAGGA	0.577000													9	140					0	0	0.080935	0	0
KCNMB1	3779	broad.mit.edu	37	5	169805873	169805873	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:169805873G>A	ENST00000274629.4	-	4	853	c.411C>T	c.(409-411)tcC>tcT	p.S137S	KCNIP1_ENST00000518527.1_Intron|KCNIP1_ENST00000377360.4_Intron	NM_004137.3	NP_004128.1	Q16558	KCMB1_HUMAN	potassium large conductance calcium-activated channel, subfamily M, beta member 1	137					platelet activation|synaptic transmission		calcium-activated potassium channel activity|potassium channel regulator activity			endometrium(1)|large_intestine(1)|lung(7)|ovary(2)	11	Renal(175;0.000159)|Lung NSC(126;0.0165)|all_lung(126;0.026)	Medulloblastoma(196;0.0109)|all_neural(177;0.0146)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.175)		CCCGAGGTGCGGAGAAGCAGT	0.622000													26	34					0	0	0.099896	0	0
HTT	3064	broad.mit.edu	37	4	3213834	3213834	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:3213834C>T	ENST00000355072.5	+	48	6738	c.6593C>T	c.(6592-6594)cCg>cTg	p.P2198L		NM_002111.6	NP_002102.4	P42858	HD_HUMAN	huntingtin	2198					establishment of mitotic spindle orientation|Golgi organization|retrograde vesicle-mediated transport, Golgi to ER|vesicle transport along microtubule	autophagic vacuole|axon|cytoplasmic vesicle membrane|cytosol|dendrite|endoplasmic reticulum|Golgi apparatus|late endosome|membrane fraction|nucleus|protein complex	beta-tubulin binding|dynactin binding|dynein intermediate chain binding|p53 binding|transcription factor binding			breast(1)|cervix(2)|endometrium(14)|kidney(5)|large_intestine(23)|lung(28)|ovary(4)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	87		all_epithelial(65;0.18)		UCEC - Uterine corpus endometrioid carcinoma (64;0.187)		CCTGCAGAGCCGGCGGCCTAC	0.498000													6	12					0	0	0.038147	0	0
MANEAL	149175	broad.mit.edu	37	1	38265671	38265671	+	Silent	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:38265671G>A	ENST00000373045.6	+	4	1551	c.1170G>A	c.(1168-1170)gcG>gcA	p.A390A	MANEAL_ENST00000525897.1_Silent_p.A196A|RP11-109P14.9_ENST00000433474.1_RNA|MANEAL_ENST00000397631.3_3'UTR|MANEAL_ENST00000329006.5_Silent_p.A168A	NM_001113482.1	NP_001106954.1	Q5VSG8	MANEL_HUMAN	mannosidase, endo-alpha-like	390						Golgi membrane|integral to membrane	hydrolase activity			endometrium(1)|large_intestine(1)|liver(1)|lung(1)|prostate(3)	7	Acute lymphoblastic leukemia(166;0.074)|all_hematologic(146;0.197)	Myeloproliferative disorder(586;0.0255)				CCCTGCAGGCGGCCCTGACAG	0.577000													3	58					0	0	0.115264	0	0
TMTC4	84899	broad.mit.edu	37	13	101315243	101315243	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:101315243G>A	ENST00000342624.5	-	5	785	c.527C>T	c.(526-528)gCt>gTt	p.A176V	TMTC4_ENST00000376234.3_Missense_Mutation_p.A157V|TMTC4_ENST00000328767.5_Intron	NM_032813.2	NP_116202.2	Q5T4D3	TMTC4_HUMAN	transmembrane and tetratricopeptide repeat containing 4	157						integral to membrane	binding			breast(3)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(5)|liver(1)|lung(14)|ovary(2)|prostate(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	34	all_neural(89;0.0837)|Medulloblastoma(90;0.18)|Lung SC(71;0.184)					AGGATGGACAGCAAACAGCAG	0.607000													3	70					0	0	0.150653	0	0
TYW1B	441250	broad.mit.edu	37	7	72209576	72209576	+	RNA	SNP	C	C	G	rs147711959	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:72209576C>G	ENST00000438125.1	-	0	579							Q6NUM6	TYW1B_HUMAN	tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)						tRNA processing		4 iron, 4 sulfur cluster binding|FMN binding|iron ion binding|oxidoreductase activity										CTCGGAGCATCGACTATGACA	0.413000													3	82					0	0	0.184627	0	0
RP11-154H17.1	0	broad.mit.edu	37	1	5652782	5652782	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:5652782delC	ENST00000413887.1	-	0	155																											gggtgatctgcccaccttggc	0.493													2	4	---	---	---	---					
UBE4B	10277	broad.mit.edu	37	1	10239600	10239606	+	Frame_Shift_Del	DEL	CAGAGAG	CAGAGAG	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:10239600_10239606delCAGAGAG	ENST00000377157.3	+	26	4165_4171	c.3104_3110delCAGAGAG	c.(3103-3111)acfs	p.TES1035fs	UBE4B_ENST00000343090.6_Frame_Shift_Del_p.TES1276fs|UBE4B_ENST00000253251.8_Frame_Shift_Del_p.TES1147fs	NM_006048.4	NP_006039.2	O95155	UBE4B_HUMAN	ubiquitination factor E4B	1276					apoptosis|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to UV	cytoplasm|ubiquitin ligase complex	enzyme binding			NS(3)|breast(1)|central_nervous_system(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(12)|lung(14)|ovary(2)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	48		all_lung(284;1.13e-05)|Lung NSC(185;1.74e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.0228)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0268)|Colorectal(212;1.42e-07)|COAD - Colon adenocarcinoma(227;2.77e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000435)|Kidney(185;0.000482)|KIRC - Kidney renal clear cell carcinoma(229;0.00164)|STAD - Stomach adenocarcinoma(132;0.0117)|READ - Rectum adenocarcinoma(331;0.046)		CAGACGCTGACAGAGAGCATGCTGGAA	0.594													19	66	---	---	---	---					
CROCCP2	84809	broad.mit.edu	37	1	16946842	16946842	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:16946842delG	ENST00000412962.1	-	0	1000																											AGGGTGCAGAGGGAAACAGGG	0.612													2	4	---	---	---	---					
ANKRD20A12P	100874392	broad.mit.edu	37	1	142728989	142728989	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:142728989delA	ENST00000595144.1	-	0	82																											CATTTTCTATAAAAACAAATT	0.308													2	4	---	---	---	---					
LINC00869	57234	broad.mit.edu	37	1	149285546	149285547	+	RNA	INS	-	-	A	rs144216017	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:149285546_149285547insA	ENST00000424684.1	+	0	254					NR_046136.1|NR_046138.1|NR_046139.1																						ttctgtctctcaaaaaaaaTGC	0.525													4	9	---	---	---	---					
RP11-404F10.2	0	broad.mit.edu	37	1	160648098	160648099	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:160648098_160648099insT	ENST00000443928.2	+	0	788				RP11-404F10.2_ENST00000588034.1_RNA|RP11-404F10.2_ENST00000598917.1_RNA																							CGATCTGATGGTTTTTTTGGAT	0.495													2	4	---	---	---	---					
RP11-306I1.2	0	broad.mit.edu	37	1	165587190	165587190	+	RNA	DEL	G	G	-	rs112121335		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:165587190delG	ENST00000452618.1	+	0	315																											ctccagaactgtgagcagtaa	0.458													3	4	---	---	---	---					
RP1-15D23.2	0	broad.mit.edu	37	1	172883192	172883192	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:172883192delT	ENST00000432694.1	+	0	223																											CTACTTATTGTTTTTTTTTTT	0.294													2	4	---	---	---	---					
LOC101928673	101928673	broad.mit.edu	37	1	173418478	173418481	+	RNA	DEL	TTCT	TTCT	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:173418478_173418481delTTCT	ENST00000367716.3	-	0	985																											ttctcttttcttctttctttcttt	0.407													4	3	---	---	---	---					
SOX13	9580	broad.mit.edu	37	1	204091465	204091466	+	Frame_Shift_Ins	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:204091465_204091466insC	ENST00000367204.1	+	9	1071_1072	c.962_963insC	c.(961-963)cccfs	p.P321fs		NM_005686.2	NP_005677.2	Q9UN79	SOX13_HUMAN	SRY (sex determining region Y)-box 13	321	Pro-rich.				anatomical structure morphogenesis	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(3)|lung(2)|ovary(2)|prostate(2)	13	all_cancers(21;0.0754)|Breast(84;0.116)|all_epithelial(62;0.189)		KIRC - Kidney renal clear cell carcinoma(13;0.0584)|Kidney(21;0.0934)|BRCA - Breast invasive adenocarcinoma(75;0.109)			TGTGTGCCCCGCCCCCCCAGCC	0.693													2	4	---	---	---	---					
RP1-272L16.1	0	broad.mit.edu	37	1	209702809	209702810	+	RNA	DEL	AC	AC	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr1:209702809_209702810delAC	ENST00000424696.2	-	0	638																											cactggacatacacacacacac	0.450													2	4	---	---	---	---					
LINC00954	400946	broad.mit.edu	37	2	20075813	20075814	+	RNA	INS	-	-	G	rs35033480	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:20075813_20075814insG	ENST00000449086.1	+	0	920					NR_033875.1																						CTCCCATGGGAGGGGGGTCCCA	0.545													3	5	---	---	---	---					
AC068490.2	0	broad.mit.edu	37	2	22446124	22446125	+	RNA	INS	-	-	GAG			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:22446124_22446125insGAG	ENST00000450551.1	-	0	70																											aagcccagactgaggaggtcct	0.426													2	4	---	---	---	---					
LOC101929418	101929418	broad.mit.edu	37	2	30352822	30352823	+	RNA	DEL	GA	GA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:30352822_30352823delGA	ENST00000420016.1	-	0	82				AC016907.3_ENST00000453606.1_RNA																							tgagccgacTGAGAGAGAGAGA	0.535													2	4	---	---	---	---					
AC006369.3	0	broad.mit.edu	37	2	37972636	37972637	+	RNA	INS	-	-	C	rs141677512	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:37972636_37972637insC	ENST00000431712.1	+	0	311																											GTTTTGGAGCACCCTAAGGCCC	0.455													2	4	---	---	---	---					
LOC101927043	101927043	broad.mit.edu	37	2	47481765	47481766	+	RNA	INS	-	-	CCTGCTCAGAAGATTCAG	rs146509686	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:47481765_47481766insCCTGCTCAGAAGATTCAG	ENST00000419035.1	-	0	66																		p.0?(2)|p.?(1)									TGTCTGCACATCCTGCTCAGCA	0.559													2	4	---	---	---	---					
LOC730100	730100	broad.mit.edu	37	2	51664890	51664893	+	RNA	DEL	CATC	CATC	-	rs142816933		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:51664890_51664893delCATC	ENST00000440698.1	+	0	694																											agttgtgctacatccatacaatgt	0.309													5	4	---	---	---	---					
RP11-482H16.1	0	broad.mit.edu	37	2	56386062	56386062	+	RNA	DEL	A	A	-	rs111318970		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:56386062delA	ENST00000607540.1	+	0	111				RP11-481J13.1_ENST00000606639.1_lincRNA																							cagcttggggaaaaaaaaaaa	0.363													3	4	---	---	---	---					
LINC01122	400955	broad.mit.edu	37	2	59176331	59176332	+	RNA	DEL	GT	GT	-	rs6723345		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:59176331_59176332delGT	ENST00000452840.1	+	0	815																											CATTTAAGGGgtgtgtgtgtgt	0.351													2	4	---	---	---	---					
RP11-444A22.1	0	broad.mit.edu	37	2	60084315	60084317	+	RNA	DEL	CTT	CTT	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:60084315_60084317delCTT	ENST00000606382.1	-	0	110																											CCTGTCTCACCTTCTGATACCTT	0.355													4	3	---	---	---	---					
AFF3	3899	broad.mit.edu	37	2	100210335	100210340	+	In_Frame_Del	DEL	GGCTGA	GGCTGA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:100210335_100210340delGGCTGA	ENST00000317233.4	-	14	2018_2023	c.1783_1788delTCAGCC	c.(1783-1788)del	p.SA595del	AFF3_ENST00000409236.1_In_Frame_Del_p.SA595del|AFF3_ENST00000409579.1_In_Frame_Del_p.SA620del|AFF3_ENST00000356421.2_In_Frame_Del_p.SA620del	NM_002285.2	NP_002276.2	P51826	AFF3_HUMAN	AF4/FMR2 family, member 3	595					multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			NS(1)|breast(3)|central_nervous_system(1)|cervix(3)|endometrium(9)|kidney(4)|large_intestine(20)|liver(1)|lung(28)|ovary(3)|pancreas(1)|prostate(4)|skin(5)|urinary_tract(3)	86						CGCCGTCCCCGGCTGAGGTCCTCTCG	0.782													2	4	---	---	---	---					
AC023347.1	0	broad.mit.edu	37	2	127071535	127071536	+	RNA	INS	-	-	TTTG	rs35221523	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:127071535_127071536insTTTG	ENST00000435352.1	+	0	373																											AATAAAGGCtttttgtttgttt	0.416													3	3	---	---	---	---					
LRP1B	53353	broad.mit.edu	37	2	141665648	141665648	+	Splice_Site	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:141665648delT	ENST00000389484.3	-	22	4291		c.e22-2			NM_018557.2	NP_061027.2	Q9NZR2	LRP1B_HUMAN	low density lipoprotein receptor-related protein 1B						protein transport|receptor-mediated endocytosis	integral to membrane	calcium ion binding			NS(5)|autonomic_ganglia(1)|biliary_tract(1)|breast(3)|central_nervous_system(7)|endometrium(25)|haematopoietic_and_lymphoid_tissue(10)|kidney(27)|large_intestine(98)|liver(4)|lung(337)|ovary(15)|pancreas(6)|prostate(11)|skin(30)|stomach(2)|upper_aerodigestive_tract(19)|urinary_tract(5)	606		all_cancers(3;1.1e-60)|all_epithelial(3;1.94e-59)|all_lung(3;1.09e-24)|Lung NSC(3;5.65e-24)|Esophageal squamous(3;5.41e-13)|Renal(3;0.000147)|Breast(3;0.000527)|Hepatocellular(3;0.011)|all_neural(3;0.014)|Colorectal(150;0.101)		UCEC - Uterine corpus endometrioid carcinoma (2;0.00139)|Epithelial(1;1.25e-24)|all cancers(1;8.86e-24)|OV - Ovarian serous cystadenocarcinoma(1;2.45e-12)|LUSC - Lung squamous cell carcinoma(1;2.97e-10)|Lung(1;6.05e-09)|BRCA - Breast invasive adenocarcinoma(221;0.0103)		TGCATCTCCCTTAAGAAAACA	0.393										TSP Lung(27;0.18)			21	23	---	---	---	---					
AC012501.2	0	broad.mit.edu	37	2	154447130	154447131	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:154447130_154447131insA	ENST00000424322.1	-	0	429																											caaaacattttaaaaaacacaa	0.292													2	4	---	---	---	---					
AC092684.1	0	broad.mit.edu	37	2	164720794	164720794	+	RNA	DEL	T	T	-	rs34147359		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:164720794delT	ENST00000429636.1	-	0	379																											tttggtagcattttagttttt	0.343													2	4	---	---	---	---					
AC013463.2	0	broad.mit.edu	37	2	165900194	165900195	+	RNA	INS	-	-	T	rs78563912		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:165900194_165900195insT	ENST00000431341.1	+	0	299																											ggctttgttcattttttttttt	0.312													3	3	---	---	---	---					
AC010127.3	0	broad.mit.edu	37	2	166818721	166818721	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:166818721delT	ENST00000595647.1	+	0	194				AC010127.3_ENST00000597623.1_RNA																							tcttcctcaatttttttttga	0.348													3	5	---	---	---	---					
AC074363.1	0	broad.mit.edu	37	2	168158312	168158313	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:168158312_168158313insC	ENST00000442316.1	+	0	164																											acccacctgggccccccaaagt	0.510													2	4	---	---	---	---					
LOC101927865	101927865	broad.mit.edu	37	2	208059369	208059369	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:208059369delT	ENST00000435643.1	+	0	285																											AGGTTTTATATCCTGTTTATG	0.239													2	4	---	---	---	---					
LINC00607	646324	broad.mit.edu	37	2	216529143	216529144	+	RNA	INS	-	-	GA	rs77416557		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:216529143_216529144insGA	ENST00000445174.1	-	0	723				AC012668.2_ENST00000417485.2_lincRNA	NR_037195.1																						tgtgtgtgtgtgAGAGAGAGAG	0.406													3	3	---	---	---	---					
LINC00607	646324	broad.mit.edu	37	2	216532072	216532072	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:216532072delT	ENST00000445174.1	-	0	723				AC012668.2_ENST00000417485.2_lincRNA	NR_037195.1																						TACATAAGTGTCCAGAAGAAA	0.403													7	3	---	---	---	---					
AC007563.5	0	broad.mit.edu	37	2	217569852	217569852	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:217569852delT	ENST00000447289.1	+	0	298																											TCTTGTTATCTTTTTTACGTT	0.274													2	4	---	---	---	---					
AC007563.5	0	broad.mit.edu	37	2	217830272	217830273	+	RNA	INS	-	-	A	rs149971596	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr2:217830272_217830273insA	ENST00000447289.1	+	0	510				AC007563.5_ENST00000607591.1_RNA																							gattcatagttaaaaaaaatca	0.386													2	4	---	---	---	---					
AC026188.1	0	broad.mit.edu	37	3	3399325	3399325	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:3399325delA	ENST00000455703.1	-	0	232																											CAATTTCATGAATGGCACTGA	0.393													2	4	---	---	---	---					
AC069277.2	0	broad.mit.edu	37	3	6544908	6544909	+	RNA	DEL	AC	AC	-	rs57548574		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:6544908_6544909delAC	ENST00000433639.1	+	0	194																											acacagacatacacacacacac	0.371													6	6	---	---	---	---					
LMCD1-AS1	100288428	broad.mit.edu	37	3	8249632	8249632	+	RNA	DEL	A	A	-	rs58402323		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:8249632delA	ENST00000452802.1	-	0	562				LMCD1-AS1_ENST00000446281.1_RNA																							actctgtatcaaaaaaaaaaa	0.463													2	4	---	---	---	---					
LMCD1-AS1	100288428	broad.mit.edu	37	3	8352815	8352815	+	RNA	DEL	C	C	-	rs111809372		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:8352815delC	ENST00000420095.1	-	0	571				LMCD1-AS1_ENST00000452802.1_RNA|LMCD1-AS1_ENST00000446281.1_RNA	NR_033378.1																						ctcccaccttccccccaccac	0.498													5	8	---	---	---	---					
LINC00620	285375	broad.mit.edu	37	3	13723620	13723625	+	RNA	DEL	TGTGCG	TGTGCG	-	rs6770634		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:13723620_13723625delTGTGCG	ENST00000419618.1	+	0	113				LINC00620_ENST00000438915.1_RNA	NR_027103.1																						tgcatgtgtatgtgcgtgtgcgtgtg	0.563													3	6	---	---	---	---					
PTPRG-AS1	100506994	broad.mit.edu	37	3	62341312	62341312	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:62341312delA	ENST00000490916.1	-	0	135				PTPRG-AS1_ENST00000495542.1_RNA																							ggaaagaaagaaaaaaaaaca	0.358													2	4	---	---	---	---					
LINC00698	285401	broad.mit.edu	37	3	63004761	63004761	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:63004761delA	ENST00000468072.1	+	0	125					NR_027104.1																						AACCCTAGGTAAAAAAAAAAA	0.388													2	4	---	---	---	---					
LINC00698	285401	broad.mit.edu	37	3	63054441	63054441	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:63054441delG	ENST00000468072.1	+	0	125					NR_027104.1																						gaatatcattgggtagtttta	0.373													2	4	---	---	---	---					
RP11-260O18.1	0	broad.mit.edu	37	3	82416333	82416334	+	RNA	INS	-	-	A	rs71616406	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:82416333_82416334insA	ENST00000470263.1	+	0	472																											agtttatagacaaaaaaaaagg	0.391													4	3	---	---	---	---					
LOC101927494	101927494	broad.mit.edu	37	3	86531807	86531807	+	RNA	DEL	T	T	-	rs147647624		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:86531807delT	ENST00000460586.1	+	0	115																											CTAGTCAACCttttttttttt	0.423													2	4	---	---	---	---					
LOC101929717	101929717	broad.mit.edu	37	3	112864257	112864257	+	RNA	DEL	G	G	-	rs7619785	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:112864257delG	ENST00000490139.1	-	0	516				RP11-572M11.4_ENST00000496389.1_RNA																							GAGATATCTCGTTTTTTTTTA	0.323													3	5	---	---	---	---					
RNA5SP143	100873410	broad.mit.edu	37	3	142310547	142310547	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:142310547delC	ENST00000516936.1	-	0	86																											TACTGAAtctcccatccaagt	0.388													2	4	---	---	---	---					
RP11-167H9.4	0	broad.mit.edu	37	3	149900955	149900956	+	RNA	INS	-	-	A	rs141432175	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:149900955_149900956insA	ENST00000489690.1	+	0	212				RP11-167H9.4_ENST00000487840.1_RNA																							GAAAAGAGTTGAAAAAAGGAAA	0.446													7	6	---	---	---	---					
RP11-23D24.2	0	broad.mit.edu	37	3	153491700	153491700	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:153491700delT	ENST00000488210.1	-	0	477																											TGATGTGGTGTTTTAAAAACA	0.284													2	4	---	---	---	---					
RP11-23D24.2	0	broad.mit.edu	37	3	153664606	153664606	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:153664606delA	ENST00000488210.1	-	0	257																											aaaggaaagcaaaaaaaaaaa	0.323													3	4	---	---	---	---					
LINC00886	730091	broad.mit.edu	37	3	156518668	156518669	+	RNA	INS	-	-	TT	rs72589364	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:156518668_156518669insTT	ENST00000472943.1	-	0	148					NR_038387.1																						actatggtgtgtactgagaaga	0.396													5	3	---	---	---	---					
RP11-324C10.1	0	broad.mit.edu	37	3	172915507	172915507	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:172915507delT	ENST00000447709.1	+	0	22																											ttttccttacttagctgtaag	0.403													2	4	---	---	---	---					
KCNMB2	10242	broad.mit.edu	37	3	178083959	178083959	+	RNA	DEL	A	A	-	rs144404709		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:178083959delA	ENST00000411727.1	-	0	190																											ctaaaaccataaaaaaaccct	0.323													8	2	---	---	---	---					
RP11-134F2.2	0	broad.mit.edu	37	3	186371312	186371313	+	RNA	DEL	CT	CT	-	rs150578280		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr3:186371312_186371313delCT	ENST00000428501.1	-	0	245				RP11-134F2.2_ENST00000455926.1_RNA																							aatgttcacactctgttcctct	0.450													5	1	---	---	---	---					
TMED11P	100379220	broad.mit.edu	37	4	1124388	1124389	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:1124388_1124389insC	ENST00000504969.1	+	0	114																											agtGCCAGTTGCCCCCCCTCCT	0.446											OREG0016029	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	4	---	---	---	---					
RP11-281P23.2	0	broad.mit.edu	37	4	11765065	11765066	+	RNA	INS	-	-	T	rs145888311		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:11765065_11765066insT	ENST00000509244.1	+	0	121				RP11-74M11.2_ENST00000506195.1_lincRNA																							TTATTTCCTAATTTTTTTTTTT	0.347													5	2	---	---	---	---					
LINC01182	101929071	broad.mit.edu	37	4	13764989	13764990	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:13764989_13764990insT	ENST00000510907.1	+	0	281																											GCCTGGGCTGGTTTTAGGACAG	0.446													2	4	---	---	---	---					
LINC01182	101929071	broad.mit.edu	37	4	13840679	13840679	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:13840679delC	ENST00000510907.1	+	0	349																											ttgcctgtatccttggctcat	0.483													2	4	---	---	---	---					
LGI2	55203	broad.mit.edu	37	4	25005320	25005321	+	Frame_Shift_Ins	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:25005320_25005321insC	ENST00000382114.4	-	8	1575_1576	c.1390_1391insG	c.(1390-1392)catfs	p.H464fs		NM_018176.3	NP_060646.2	Q8N0V4	LGI2_HUMAN	leucine-rich repeat LGI family, member 2	464						extracellular region				breast(2)|endometrium(2)|kidney(2)|large_intestine(6)|lung(15)|prostate(1)|skin(3)|stomach(2)	33		Breast(46;0.173)				CAGGGTCATGGCCCCCCGGGAT	0.515													8	260	---	---	---	---					
RP11-227F19.1	0	broad.mit.edu	37	4	41756881	41756881	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:41756881delT	ENST00000508038.1	+	0	294				RP11-227F19.2_ENST00000510602.1_lincRNA																							TAAATTTCTCTTAAGTGGAAC	0.363													2	4	---	---	---	---					
LOC101928851	101928851	broad.mit.edu	37	4	58329185	58329185	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:58329185delC	ENST00000510956.1	+	0	544																											TTGTTCACTGCCAGGCATCAG	0.398													2	4	---	---	---	---					
LOC100507053	100507053	broad.mit.edu	37	4	100099232	100099232	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:100099232delT	ENST00000500358.2	+	0	3714				RP11-696N14.1_ENST00000506454.1_RNA|RP11-696N14.1_ENST00000506160.1_RNA	NR_037884.1																						tatttttagatttgaccattt	0.328													2	4	---	---	---	---					
RP11-556I14.2	0	broad.mit.edu	37	4	105828072	105828073	+	RNA	DEL	AC	AC	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:105828072_105828073delAC	ENST00000515127.1	-	0	366																											ATGTGTGCAAACACACACACAC	0.391													2	4	---	---	---	---					
RP11-125O18.1	0	broad.mit.edu	37	4	128134846	128134846	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:128134846delG	ENST00000504050.1	-	0	368																											agctgaggcaggagaatcgct	0.498													2	4	---	---	---	---					
RP11-138I17.1	0	broad.mit.edu	37	4	138099360	138099360	+	RNA	DEL	G	G	-	rs34568542		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:138099360delG	ENST00000505736.1	-	0	63																											gaaattagcagggtgtagtgg	0.517													3	3	---	---	---	---					
SLC7A11-AS1	641364	broad.mit.edu	37	4	139049594	139049594	+	RNA	DEL	G	G	-	rs138361626		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:139049594delG	ENST00000510767.1	+	0	1725				SLC7A11-AS1_ENST00000512786.1_RNA|LINC00616_ENST00000514600.1_lincRNA	NR_038380.1																						ttttttttttgtttttttttt	0.448													4	2	---	---	---	---					
RP11-284M14.1	0	broad.mit.edu	37	4	143956648	143956649	+	RNA	INS	-	-	AAC	rs138799383	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:143956648_143956649insAAC	ENST00000507826.1	-	0	354																											TTCTTGTATGTaacaacaacaa	0.312													3	3	---	---	---	---					
RP11-284M14.1	0	broad.mit.edu	37	4	143993074	143993074	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:143993074delT	ENST00000507826.1	-	0	354																											tcacttgctgttttttttctt	0.483													2	4	---	---	---	---					
RP13-578N3.3	0	broad.mit.edu	37	4	144643304	144643305	+	RNA	INS	-	-	AG	rs71588285		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:144643304_144643305insAG	ENST00000499587.2	+	0	35																											gtcagagtgccagagagagaga	0.480													2	4	---	---	---	---					
RP11-526A4.1	0	broad.mit.edu	37	4	150487668	150487669	+	RNA	DEL	GA	GA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:150487668_150487669delGA	ENST00000511993.1	-	0	1181																											ACACATGTACgagagagagaga	0.411													3	5	---	---	---	---					
RP11-310I9.1	0	broad.mit.edu	37	4	168899106	168899107	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:168899106_168899107insA	ENST00000506926.1	-	0	103																											actatgcagccaaaaaaatgag	0.381													2	4	---	---	---	---					
RP11-130F10.1	0	broad.mit.edu	37	4	178486117	178486118	+	RNA	DEL	CA	CA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:178486117_178486118delCA	ENST00000507023.1	+	0	581																											cacacacacgcacacacacaca	0.401													2	4	---	---	---	---					
LOC90768	90768	broad.mit.edu	37	4	182860216	182860217	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:182860216_182860217insA	ENST00000509012.1	-	0	378																											AGTAATGTAAGAAAAAAAAAGA	0.277													2	4	---	---	---	---					
RP11-818C3.1	0	broad.mit.edu	37	4	189920091	189920092	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr4:189920091_189920092insT	ENST00000508799.1	-	0	306																											aaatcacgtggtttttgtctct	0.337													2	4	---	---	---	---					
RP11-259O2.1	0	broad.mit.edu	37	5	1943994	1943995	+	RNA	INS	-	-	G	rs78186681	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:1943994_1943995insG	ENST00000511693.1	+	0	123																											gagcacaccatgtgtctgactt	0.470													5	2	---	---	---	---					
CTD-2066L21.3	0	broad.mit.edu	37	5	33120565	33120566	+	RNA	INS	-	-	A	rs56190787		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:33120565_33120566insA	ENST00000510327.1	-	0	346																											TCAAAACCAAGAAAAAAAAAAA	0.347													2	4	---	---	---	---					
CTD-2116N24.1	0	broad.mit.edu	37	5	38058253	38058253	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:38058253delT	ENST00000513039.2	+	0	233																											atggatgctatttttttttca	0.308													2	4	---	---	---	---					
LINC01331	104310351	broad.mit.edu	37	5	73816036	73816037	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:73816036_73816037insG	ENST00000507781.1	-	0	307																											AGGGTGGGGGTGGGGGGCagga	0.465													2	4	---	---	---	---					
LOC101926941	101926941	broad.mit.edu	37	5	141804304	141804304	+	RNA	DEL	T	T	-	rs35600923		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:141804304delT	ENST00000510311.1	+	0	506				AC005592.2_ENST00000425963.1_RNA|AC005592.2_ENST00000443800.1_RNA																							AGCATATTCCTTTTTTTTTTT	0.438													4	3	---	---	---	---					
CTC-255N20.1	0	broad.mit.edu	37	5	146575590	146575590	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:146575590delA	ENST00000504297.1	-	0	322																											CACTATCAAGAAAAAAAAAAA	0.368													2	4	---	---	---	---					
CTC-295J13.3	0	broad.mit.edu	37	5	147619207	147619208	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:147619207_147619208insA	ENST00000513133.1	+	0	77																											acagagttaagaaaAAAAAAGG	0.327													2	4	---	---	---	---					
LOC101927115	101927115	broad.mit.edu	37	5	151610072	151610073	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:151610072_151610073insT	ENST00000524295.1	+	0	370																											CTTCATCAAGCTTTTTGAGGTT	0.317													2	4	---	---	---	---					
CTC-535M15.2	0	broad.mit.edu	37	5	164859940	164859940	+	RNA	DEL	T	T	-	rs34057925		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr5:164859940delT	ENST00000522189.1	+	0	21																											tttttaatcgttttttttttt	0.423													3	3	---	---	---	---					
RP11-532F6.5	0	broad.mit.edu	37	6	766744	766745	+	RNA	INS	-	-	TT	rs147212980		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:766744_766745insTT	ENST00000607084.1	+	0	1207																											TTAAATGAGACTTTTTTTTTTT	0.421													2	4	---	---	---	---					
RP1-80N2.3	0	broad.mit.edu	37	6	6682127	6682128	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:6682127_6682128insC	ENST00000563225.1	-	0	1738_1739																											TATATTTTGGTCCCCCCCCCAT	0.366													2	4	---	---	---	---					
FOXP4-AS1	101060264	broad.mit.edu	37	6	41465529	41465530	+	RNA	DEL	CA	CA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr6:41465529_41465530delCA	ENST00000440194.1	-	0	155																											CATGCACACGCACACACACACA	0.465													2	4	---	---	---	---					
AC004538.3	0	broad.mit.edu	37	7	11238289	11238292	+	RNA	DEL	TTCT	TTCT	-	rs62438691	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:11238289_11238292delTTCT	ENST00000441110.1	+	0	138				AC004538.3_ENST00000599917.1_RNA|AC004538.3_ENST00000428967.1_RNA																							ccttccctccttctttccttccct	0.525													2	4	---	---	---	---					
AC004538.3	0	broad.mit.edu	37	7	11259279	11259279	+	RNA	DEL	A	A	-	rs59505681		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:11259279delA	ENST00000441110.1	+	0	138				AC004538.3_ENST00000599917.1_RNA|AC004538.3_ENST00000428967.1_RNA																							gacctgatgtaaaatcacaag	0.383													7	1	---	---	---	---					
AC004538.3	0	broad.mit.edu	37	7	11278139	11278140	+	RNA	INS	-	-	TACAA	rs146791303	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:11278139_11278140insTACAA	ENST00000599875.1	+	0	186				AC004538.3_ENST00000428967.1_RNA|AC004538.3_ENST00000441110.1_RNA																							AAAGGCATATTTACAGGTAATA	0.287													2	4	---	---	---	---					
AC004901.1	0	broad.mit.edu	37	7	46966880	46966880	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:46966880delG	ENST00000433337.1	-	0	301																											TTTCAGGGCAGGGGCCATAAG	0.408													2	4	---	---	---	---					
AC004901.1	0	broad.mit.edu	37	7	47029908	47029911	+	RNA	DEL	GTGA	GTGA	-	rs73088619		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:47029908_47029911delGTGA	ENST00000433337.1	-	0	237																											GTGTGTGTGTGTgagagagagaga	0.451													5	1	---	---	---	---					
RP5-945F2.3	0	broad.mit.edu	37	7	67638700	67638701	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:67638700_67638701insC	ENST00000446187.1	-	0	444																											GAGGACTCCAGCCCCCCCAGCT	0.535													3	3	---	---	---	---					
RP5-945F2.3	0	broad.mit.edu	37	7	67704171	67704172	+	RNA	INS	-	-	GTTTT	rs115888660	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:67704171_67704172insGTTTT	ENST00000446187.1	-	0	179																											cttactttttcgttttgttttg	0.431													2	4	---	---	---	---					
GTF2IRD2P1	401375	broad.mit.edu	37	7	72679522	72679523	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:72679522_72679523insT	ENST00000425256.1	-	0	432					NR_002164.1																						TTTtttgtttgttttttttttt	0.381													2	4	---	---	---	---					
MTERF1	7978	broad.mit.edu	37	7	91493868	91493869	+	RNA	INS	-	-	A	rs59801614		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:91493868_91493869insA	ENST00000454222.1	-	0	93																											gaccctgtctcaaaaaaaaaaa	0.401													2	4	---	---	---	---					
DLX6-AS1	285987	broad.mit.edu	37	7	96602551	96602551	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:96602551delT	ENST00000430027.2	-	0	1386				DLX6-AS1_ENST00000430404.2_RNA|DLX6-AS1_ENST00000437331.2_RNA|DLX6-AS1_ENST00000431497.2_RNA|DLX6-AS1_ENST00000605417.1_RNA|DLX6-AS1_ENST00000452769.2_RNA	NR_015448.1																						AAGCCAGAGCTTTGCTGTTCT	0.473													2	4	---	---	---	---					
LINC01510	100996266	broad.mit.edu	37	7	116247342	116247342	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:116247342delC	ENST00000458082.1	-	0	222																											TCCTACTGCTCCCAATAATTA	0.323													2	4	---	---	---	---					
RP11-3B12.5	0	broad.mit.edu	37	7	124791711	124791712	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:124791711_124791712insG	ENST00000454957.1	-	0	267_268																											TATCaggtagcggggggaaagt	0.381													2	4	---	---	---	---					
AC073934.6	0	broad.mit.edu	37	7	127291541	127291542	+	RNA	INS	-	-	AA	rs2308067	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:127291541_127291542insAA	ENST00000490314.1	-	0	340																											GTCCTTCCTCTGAGACATTTAT	0.530													6	3	---	---	---	---					
AC024084.1	0	broad.mit.edu	37	7	135710987	135710988	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:135710987_135710988insT	ENST00000440744.2	+	0	28																											taaattggtgctttttttcctt	0.277													2	4	---	---	---	---					
LOC349160	349160	broad.mit.edu	37	7	136496022	136496023	+	RNA	DEL	AG	AG	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:136496022_136496023delAG	ENST00000439694.1	-	0	343				AC009264.1_ENST00000597642.1_RNA|AC009264.1_ENST00000586239.1_RNA|AC009264.1_ENST00000598184.1_RNA|AC009264.1_ENST00000593789.1_RNA|AC009264.1_ENST00000592183.1_RNA																							agcttagcacagagagagagag	0.485													2	4	---	---	---	---					
WEE2-AS1	285962	broad.mit.edu	37	7	141405890	141405890	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:141405890delA	ENST00000488785.1	-	0	842					NR_015392.1																						CAATGTGACCAAAAAAATAGT	0.413													2	4	---	---	---	---					
LOC285889	285889	broad.mit.edu	37	7	156233602	156233603	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr7:156233602_156233603insC	ENST00000436670.1	-	0	1491					NR_038232.1																						CTTCTCACCTGCCCCCCCGGCA	0.604													3	5	---	---	---	---					
LOC100128993	100128993	broad.mit.edu	37	8	19077300	19077300	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:19077300delG	ENST00000518417.1	-	0	278																											AAGAGTTCCAGGCATGCAAAA	0.368													2	4	---	---	---	---					
RP11-624C23.1	0	broad.mit.edu	37	8	24412947	24412948	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:24412947_24412948insT	ENST00000519689.1	-	0	184																											ATTTCTTTTTGTTTTTGTTTTC	0.411													2	4	---	---	---	---					
LINC00589	619351	broad.mit.edu	37	8	29604024	29604025	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:29604024_29604025insG	ENST00000506121.3	-	0	95					NR_026765.1																						gcctcaggtctgggggctcaag	0.505													2	4	---	---	---	---					
POTEA	340441	broad.mit.edu	37	8	43187977	43187978	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:43187977_43187978insG	ENST00000522175.2	+	0	1051							Q6S8J7	POTEA_HUMAN	POTE ankyrin domain family, member A											breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(27)|ovary(1)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	46						cttgctaggttggggaagttcc	0.416													2	4	---	---	---	---					
LINC01289	286184	broad.mit.edu	37	8	64692161	64692162	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:64692161_64692162insT	ENST00000519550.1	+	0	1572_1573				RP11-32K4.1_ENST00000523191.1_RNA|RP11-32K4.1_ENST00000524360.1_RNA	NR_038875.1																						ttttctttttcttttttttttt	0.351													5	3	---	---	---	---					
LOC102724874	102724874	broad.mit.edu	37	8	78421529	78421530	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:78421529_78421530insA	ENST00000518706.2	+	0	471																											tacacccacacaaaaatgctgg	0.347													2	4	---	---	---	---					
NDUFAF6	137682	broad.mit.edu	37	8	96095172	96095175	+	RNA	DEL	TTGT	TTGT	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:96095172_96095175delTTGT	ENST00000518598.1	-	0	383																											cagacgtgagTTGTTTGTTTGTtt	0.544													3	3	---	---	---	---					
LOC101927172	101927172	broad.mit.edu	37	8	102485537	102485538	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:102485537_102485538insA	ENST00000520268.1	-	0	50																											actttgcttgtaaaaacaaact	0.312													2	4	---	---	---	---					
RP11-1082L8.3	0	broad.mit.edu	37	8	125850054	125850055	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:125850054_125850055insT	ENST00000533496.1	-	0	293																											tccttccttccttccttccttc	0.396													2	4	---	---	---	---					
CASC8	727677	broad.mit.edu	37	8	128337277	128337278	+	RNA	INS	-	-	CA	rs140625353	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr8:128337277_128337278insCA	ENST00000502082.1	-	0	1176				CASC8_ENST00000501396.1_RNA|CASC8_ENST00000523825.1_RNA																							acacatacgcgcgcacacacac	0.347													3	3	---	---	---	---					
GLIS3	169792	broad.mit.edu	37	9	4303268	4303269	+	RNA	INS	-	-	AC	rs140532162	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:4303268_4303269insAC	ENST00000440674.1	+	0	34																											TTAAAacacagacacacacaca	0.411													3	5	---	---	---	---					
RP11-536O18.1	0	broad.mit.edu	37	9	13452369	13452369	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:13452369delA	ENST00000428006.2	+	0	103																											ATTAAGGAGTAAAGAAAAATG	0.368													2	4	---	---	---	---					
LINC01410	103352539	broad.mit.edu	37	9	66466327	66466327	+	RNA	DEL	G	G	-	rs58593495		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:66466327delG	ENST00000424345.1	+	0	960																											agcaggtccaggaatgcactt	0.483													11	9	---	---	---	---					
RP11-764K9.1	0	broad.mit.edu	37	9	68407616	68407616	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:68407616delA	ENST00000417843.2	-	0	67																											tggatcaagcagaagaaatag	0.343													4	6	---	---	---	---					
LINC01508	101927873	broad.mit.edu	37	9	93121621	93121621	+	RNA	DEL	A	A	-	rs75783550		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:93121621delA	ENST00000425666.1	-	0	261																											GAAAGAAGTTAACGTTTGTTT	0.274													3	3	---	---	---	---					
RP11-308N19.1	0	broad.mit.edu	37	9	109206900	109206900	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:109206900delG	ENST00000435485.1	+	0	171																											ccagctatttgggaggctgag	0.547													2	4	---	---	---	---					
LINC01505	100996590	broad.mit.edu	37	9	109402095	109402095	+	RNA	DEL	A	A	-	rs66616752		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr9:109402095delA	ENST00000444985.2	+	0	451																											catctctactaaaaaaaaaaa	0.498													3	4	---	---	---	---					
LINC00701	399708	broad.mit.edu	37	10	2356970	2356970	+	RNA	DEL	A	A	-	rs11349525		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:2356970delA	ENST00000418295.1	-	0	46					NR_038884.1																						GGATAGAGAGAAGAGGGGGCA	0.502													2	4	---	---	---	---					
RP11-799O21.2	0	broad.mit.edu	37	10	6946899	6946900	+	RNA	INS	-	-	T	rs140231960	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:6946899_6946900insT	ENST00000457632.1	-	0	44																											aggcagagggctttttttggtg	0.386													3	6	---	---	---	---					
LINC00709	100507163	broad.mit.edu	37	10	9318698	9318699	+	RNA	INS	-	-	TG	rs61602745		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:9318698_9318699insTG	ENST00000458168.1	+	0	28																											ATTAATATATAtgtgtgtgtgt	0.441													3	5	---	---	---	---					
NEBL	10529	broad.mit.edu	37	10	21169750	21169750	+	Frame_Shift_Del	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:21169750delG	ENST00000377122.4	-	5	849	c.453delC	c.(451-453)gcfs	p.A151fs	NEBL_ENST00000377119.1_Frame_Shift_Del_p.A151fs|NEBL_ENST00000377159.4_Intron|NEBL_ENST00000417816.2_Intron	NM_006393.2	NP_006384.1	O76041	NEBL_HUMAN	nebulette	151					regulation of actin filament length		actin binding|structural constituent of muscle			NS(2)|breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(14)|lung(22)|ovary(2)|pancreas(1)|prostate(2)|skin(8)|stomach(5)|upper_aerodigestive_tract(1)|urinary_tract(2)	70						TGACCTCCATGGCATGTTTAA	0.408													7	70	---	---	---	---					
ZEB1	6935	broad.mit.edu	37	10	31809832	31809833	+	Frame_Shift_Ins	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:31809832_31809833insG	ENST00000446923.2	+	7	1912_1913	c.1521_1522insG	c.(1519-1524)gaggggfs	p.EG507fs	ZEB1_ENST00000361642.5_Frame_Shift_Ins_p.EG524fs|ZEB1_ENST00000559858.1_3'UTR|ZEB1_ENST00000320985.10_Frame_Shift_Ins_p.EG523fs|ZEB1_ENST00000560721.2_Frame_Shift_Ins_p.EG503fs|ZEB1_ENST00000542815.3_Frame_Shift_Ins_p.EG456fs	NM_001128128.2|NM_001174094.1	NP_001121600.1|NP_001167565.1	P37275	ZEB1_HUMAN	zinc finger E-box binding homeobox 1	523					cell proliferation|immune response|negative regulation of transcription from RNA polymerase II promoter|positive regulation of neuron differentiation	cytoplasm	E-box binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|transcription corepressor activity|zinc ion binding			NS(2)|breast(4)|central_nervous_system(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(14)|lung(38)|ovary(3)|skin(6)|upper_aerodigestive_tract(4)	77		Prostate(175;0.0156)				AAAGCTTTGAAGGGGGGGTGAA	0.371													14	169	---	---	---	---					
RP11-672F9.1	0	broad.mit.edu	37	10	38567539	38567539	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:38567539delA	ENST00000450980.1	+	0	144																											AATGGATGTTAATTTTTTTGT	0.318													2	4	---	---	---	---					
LINC00842	643650	broad.mit.edu	37	10	47109455	47109456	+	RNA	INS	-	-	C	rs11413452		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:47109455_47109456insC	ENST00000422732.2	-	0	435					NR_033957.1																						tagagcaTCCTCCCCCCCCATC	0.520													3	6	---	---	---	---					
RP11-135D11.2	0	broad.mit.edu	37	10	61349241	61349242	+	RNA	INS	-	-	CACT	rs148571823	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:61349241_61349242insCACT	ENST00000450677.1	+	0	222																											taggcattaggcactcctaaac	0.351													4	3	---	---	---	---					
NUTM2B-AS1	101060691	broad.mit.edu	37	10	81519155	81519155	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:81519155delA	ENST00000601369.1	-	0	59				RP11-119F19.2_ENST00000596088.1_RNA|RP11-119F19.2_ENST00000600376.1_RNA																							CCTATTAAGCAAAAGGATTTC	0.279													2	4	---	---	---	---					
RP11-80H5.9	0	broad.mit.edu	37	10	91433239	91433239	+	RNA	DEL	T	T	-	rs77393911		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:91433239delT	ENST00000449882.2	-	0	227																											tcctGAtttcttttttttttt	0.468													3	4	---	---	---	---					
RP11-236B18.2	0	broad.mit.edu	37	10	92763342	92763343	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:92763342_92763343insC	ENST00000412362.1	+	0	134																											aggaaaatccgcccccatgatt	0.446													2	4	---	---	---	---					
LBX1-AS1	399806	broad.mit.edu	37	10	102991465	102991466	+	RNA	INS	-	-	AG	rs138692572	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr10:102991465_102991466insAG	ENST00000547077.1	+	0	221				LBX1-AS1_ENST00000546988.1_RNA																							AATagagagaaagagagagaga	0.554													2	4	---	---	---	---					
GVINP1	387751	broad.mit.edu	37	11	6761214	6761214	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:6761214delT	ENST00000526769.2	-	0	91																											CCCTTAGTTGTTGTCAACTCT	0.428													2	4	---	---	---	---					
GVINP1	387751	broad.mit.edu	37	11	6765436	6765436	+	RNA	DEL	T	T	-	rs11305943		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:6765436delT	ENST00000526769.2	-	0	91																											ttttaccatgttggccaggct	0.527													2	4	---	---	---	---					
BBOX1-AS1	103695435	broad.mit.edu	37	11	27166953	27166954	+	RNA	INS	-	-	TT	rs140528197	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:27166953_27166954insTT	ENST00000530430.1	-	0	667				RP11-1L12.3_ENST00000526061.1_RNA|RP11-1L12.3_ENST00000525302.1_RNA																							tataagaaccatttttttttga	0.361													2	4	---	---	---	---					
RP11-646J21.2	0	broad.mit.edu	37	11	33840247	33840248	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:33840247_33840248insC	ENST00000525320.1	-	0	217																											GCTGCAATGGACCCCCCAGGTA	0.579													2	4	---	---	---	---					
LOC440040	440040	broad.mit.edu	37	11	49821709	49821710	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:49821709_49821710insA	ENST00000527477.1	+	0	1397																											aagataataagaaaaacagctt	0.356													2	4	---	---	---	---					
LOC283194	283194	broad.mit.edu	37	11	58761623	58761624	+	RNA	INS	-	-	TGA	rs68061929	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:58761623_58761624insTGA	ENST00000533954.1	-	0	507				RP11-142C4.6_ENST00000532098.1_RNA	NR_033853.1																						TATATATGAATTGAGGCAATGG	0.322													3	3	---	---	---	---					
LOC101928944	101928944	broad.mit.edu	37	11	80471832	80471832	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:80471832delT	ENST00000526840.1	-	0	849																											gcatattatgtttttccctta	0.279													2	4	---	---	---	---					
LOC101928989	101928989	broad.mit.edu	37	11	81651244	81651244	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:81651244delC	ENST00000500502.1	-	0	940																											AAAGAGACAACAAATAGTAGA	0.383													2	4	---	---	---	---					
MMP7	4316	broad.mit.edu	37	11	102401335	102401335	+	Frame_Shift_Del	DEL	C	C	-	rs147586158		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:102401335delC	ENST00000260227.4	-	1	149	c.97delG	c.(97-99)aafs	p.E33fs		NM_002423.3	NP_002414.1	P09237	MMP7_HUMAN	matrix metallopeptidase 7 (matrilysin, uterine)	33					collagen catabolic process|proteolysis	extracellular space|proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			large_intestine(6)|lung(3)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	12	all_cancers(8;2.04e-05)|all_epithelial(12;0.00053)|Lung NSC(15;0.139)	Acute lymphoblastic leukemia(157;0.000967)|all_hematologic(158;0.0033)	Epithelial(9;0.0105)|all cancers(10;0.0496)|Lung(13;0.109)|LUSC - Lung squamous cell carcinoma(19;0.151)	BRCA - Breast invasive adenocarcinoma(274;0.0147)		TGAGCCTGTTCCCACTGTAGC	0.532													9	29	---	---	---	---					
RP11-469N6.1	0	broad.mit.edu	37	11	134609011	134609012	+	RNA	DEL	TG	TG	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr11:134609011_134609012delTG	ENST00000513405.1	+	0	947																											tgtgtatgtctgtgtgtgtgtg	0.465													4	3	---	---	---	---					
EPS8	2059	broad.mit.edu	37	12	15834162	15834163	+	Frame_Shift_Ins	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:15834162_15834163insA	ENST00000281172.5	-	3	569_570	c.133_134insT	c.(133-135)tgafs	p.*45fs	EPS8_ENST00000543612.1_Frame_Shift_Ins_p.*45fs|EPS8_ENST00000543523.1_Frame_Shift_Ins_p.*45fs	NM_004447.5	NP_004438.3	Q12929	EPS8_HUMAN	epidermal growth factor receptor pathway substrate 8	45					cell proliferation|epidermal growth factor receptor signaling pathway		SH3/SH2 adaptor activity			NS(1)|breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(9)|ovary(3)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	33		all_epithelial(100;1.87e-05)|Breast(259;0.000286)|Hepatocellular(102;0.244)		BRCA - Breast invasive adenocarcinoma(232;4.29e-05)|GBM - Glioblastoma multiforme(207;0.0264)		AAACCTACCATAAAGGGCCTTT	0.322													45	70	---	---	---	---					
LOC101928441	101928441	broad.mit.edu	37	12	23263407	23263412	+	RNA	DEL	GCTGTG	GCTGTG	-	rs145418499		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:23263407_23263412delGCTGTG	ENST00000540895.1	+	0	1185																											TGTGCCCTTTGCTGTGGCTGTTAATA	0.359													2	4	---	---	---	---					
RP11-1020M18.10	0	broad.mit.edu	37	12	52802664	52802665	+	RNA	DEL	GA	GA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:52802664_52802665delGA	ENST00000548135.1	+	0	82																											aaggggggttgagagagaggag	0.465													2	4	---	---	---	---					
RPS11P6	729258	broad.mit.edu	37	12	64654268	64654268	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:64654268delA	ENST00000535684.1	+	0	319																											tctccaaaagaaaaaaaaaaa	0.383													3	5	---	---	---	---					
FLJ41278	400046	broad.mit.edu	37	12	65345256	65345257	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:65345256_65345257insT	ENST00000535058.1	+	0	594				RP11-766N7.4_ENST00000510459.2_lincRNA	NR_033988.1																						CTAGTTAGCCATTTTTTTTTTA	0.342													3	5	---	---	---	---					
RP11-956E11.1	0	broad.mit.edu	37	12	69846633	69846634	+	RNA	DEL	TG	TG	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:69846633_69846634delTG	ENST00000549261.1	+	0	219																											ccagctaatttgtgtgtgtgtg	0.535													4	9	---	---	---	---					
RP11-588H23.3	0	broad.mit.edu	37	12	70879558	70879558	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:70879558delA	ENST00000548687.1	+	0	243				RP11-588H23.3_ENST00000548924.1_RNA|RP11-588H23.3_ENST00000551438.1_RNA|RP11-588H23.3_ENST00000549616.1_RNA|RP11-588H23.3_ENST00000549359.1_RNA|RP11-588H23.3_ENST00000549460.1_RNA																							agggcattagaaaaaaaaaag	0.423													2	4	---	---	---	---					
RP11-314D7.4	0	broad.mit.edu	37	12	74032118	74032118	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:74032118delA	ENST00000549058.1	-	0	97																											aatttacaagaaaaaaaaaac	0.348													2	4	---	---	---	---					
RP11-54A9.1	0	broad.mit.edu	37	12	76696323	76696323	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:76696323delT	ENST00000553247.1	+	0	425																											ctttctgcaatttccctttgg	0.488													2	4	---	---	---	---					
LINC01490	101928420	broad.mit.edu	37	12	81160348	81160349	+	RNA	INS	-	-	A	rs72176091	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:81160348_81160349insA	ENST00000551399.1	+	0	75																											GAAAGGAAAATAAAAAAAACAA	0.371													4	2	---	---	---	---					
RP11-511B23.2	0	broad.mit.edu	37	12	93567498	93567499	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:93567498_93567499insA	ENST00000549930.1	-	0	98																											tgacacatttgaatttatgttt	0.436													2	4	---	---	---	---					
RP11-541G9.1	0	broad.mit.edu	37	12	97524159	97524159	+	RNA	DEL	T	T	-	rs74465598		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:97524159delT	ENST00000552238.1	+	0	39																											ACCCAAGATGTTTCGTAAAGA	0.468													3	4	---	---	---	---					
LOC101927592	101927592	broad.mit.edu	37	12	127450420	127450421	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr12:127450420_127450421insA	ENST00000512624.2	-	0	685																											ACACTTGACCCAAAAAAACTGA	0.332													3	3	---	---	---	---					
SMIM2-AS1	101929212	broad.mit.edu	37	13	44747154	44747154	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:44747154delT	ENST00000437867.1	+	0	219																											agaatacaagttttttttttt	0.378													3	5	---	---	---	---					
RNF219-AS1	100874222	broad.mit.edu	37	13	78993840	78993840	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:78993840delA	ENST00000607862.1	+	0	315				RNF219-AS1_ENST00000605996.1_RNA|RNF219-AS1_ENST00000430549.2_RNA|RNF219-AS1_ENST00000560209.2_RNA|RNF219-AS1_ENST00000606124.1_RNA|RNF219-AS1_ENST00000606376.1_RNA|RNF219-AS1_ENST00000606429.1_RNA|RNF219-AS1_ENST00000444769.3_RNA|RNF219-AS1_ENST00000606803.1_RNA|RNF219-AS1_ENST00000607860.1_RNA|RNF219-AS1_ENST00000607220.1_RNA|RNF219-AS1_ENST00000607205.1_RNA																							AAATCGCTATAAAAAGCTCAT	0.418													2	4	---	---	---	---					
LINC00559	100874187	broad.mit.edu	37	13	90743034	90743037	+	RNA	DEL	AATA	AATA	-	rs67132583		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr13:90743034_90743037delAATA	ENST00000569476.1	-	0	3282					NR_047489.1																						ATAAACAATTAATAAATAAATGTC	0.230													4	3	---	---	---	---					
LOC102724917	102724917	broad.mit.edu	37	14	29307286	29307286	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:29307286delT	ENST00000551588.1	+	0	388																											actgcaggcattttttttttt	0.398													4	2	---	---	---	---					
RP11-305B6.3	0	broad.mit.edu	37	14	44474414	44474415	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:44474414_44474415insA	ENST00000553827.1	-	0	194																											gaagaaagaagaaggagaagga	0.455													2	4	---	---	---	---					
AL162759.1	0	broad.mit.edu	37	14	54272680	54272680	+	RNA	DEL	T	T	-	rs61049350		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:54272680delT	ENST00000418927.1	-	0	437																											ATCCCTGCTATTTTTTTTCTT	0.318													6	3	---	---	---	---					
RP11-26L16.1	0	broad.mit.edu	37	14	86867580	86867581	+	RNA	INS	-	-	AAG	rs10637165		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:86867580_86867581insAAG	ENST00000553679.1	+	0	158_159																											ttaaaaaaaaaaagaagaagaa	0.406													3	5	---	---	---	---					
ATXN3	4287	broad.mit.edu	37	14	92515536	92515537	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:92515536_92515537insG	ENST00000568290.1	-	0	518																											agggagtagaagggggaatgga	0.475													2	4	---	---	---	---					
RP11-61O1.1	0	broad.mit.edu	37	14	98604201	98604202	+	RNA	DEL	CT	CT	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr14:98604201_98604202delCT	ENST00000555776.1	-	0	121				RP11-61O1.2_ENST00000557072.1_lincRNA																							ctctctctccctctctctctct	0.465													3	3	---	---	---	---					
HERC2P3	283755	broad.mit.edu	37	15	20594769	20594770	+	RNA	DEL	AT	AT	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:20594769_20594770delAT	ENST00000428453.1	-	0	4041																				central_nervous_system(1)|endometrium(11)|kidney(2)|large_intestine(1)|lung(14)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	35						ATAAATACACATGATTTCAAGA	0.396													2	4	---	---	---	---					
HERC2P3	283755	broad.mit.edu	37	15	20602750	20602751	+	RNA	INS	-	-	A	rs149106155		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:20602750_20602751insA	ENST00000428453.1	-	0	4041																				central_nervous_system(1)|endometrium(11)|kidney(2)|large_intestine(1)|lung(14)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	35						ttttacatgtgaaaaaataggc	0.322													4	5	---	---	---	---					
LOC100128714	100128714	broad.mit.edu	37	15	26176849	26176850	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:26176849_26176850insG	ENST00000383019.2	+	0	207					NR_040082.1																						ttttaactcccgggggacattt	0.485													2	4	---	---	---	---					
RP11-208K4.1	0	broad.mit.edu	37	15	48242553	48242553	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:48242553delA	ENST00000560900.1	+	0	195																											ctgtaactggaaaaggggaaa	0.428													2	4	---	---	---	---					
RP11-50C13.1	0	broad.mit.edu	37	15	58881784	58881785	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:58881784_58881785insG	ENST00000560594.1	+	0	406																											tgCAGTCCTTTGGGGGCTGTGA	0.480													2	4	---	---	---	---					
RP11-59H7.3	0	broad.mit.edu	37	15	59417751	59417751	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:59417751delT	ENST00000559026.1	+	0	532																											GGCATTGAACttttttttttt	0.388													2	4	---	---	---	---					
LOC102723344	102723344	broad.mit.edu	37	15	63689622	63689623	+	RNA	INS	-	-	T	rs147408761	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:63689622_63689623insT	ENST00000559821.1	+	0	174																											aaaccagtgggttttttggggt	0.381													2	4	---	---	---	---					
RP11-152L20.3	0	broad.mit.edu	37	15	92818808	92818808	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:92818808delT	ENST00000561674.1	-	0	185																											acatccagcatttttttcatt	0.269													2	4	---	---	---	---					
RP11-386M24.9	0	broad.mit.edu	37	15	93157938	93157938	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:93157938delG	ENST00000607766.1	+	0	168																											aaaggcacctggcacccagga	0.542													2	4	---	---	---	---					
RP11-739G5.1	0	broad.mit.edu	37	15	94233651	94233652	+	RNA	DEL	AC	AC	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:94233651_94233652delAC	ENST00000554318.2	+	0	324																											tagaacccagacacacacacac	0.426													2	4	---	---	---	---					
LINC01581	101927112	broad.mit.edu	37	15	94594744	94594745	+	RNA	DEL	AC	AC	-	rs55865577		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:94594744_94594745delAC	ENST00000558874.1	-	0	1141																											acagacccatacacacacacac	0.450													3	4	---	---	---	---					
RP11-4G2.1	0	broad.mit.edu	37	15	96574478	96574479	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:96574478_96574479insG	ENST00000561051.1	-	0	142																											TGGCCCATTTTCTTTTTCTTTT	0.371													2	4	---	---	---	---					
RP11-654A16.3	0	broad.mit.edu	37	15	99566557	99566557	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:99566557delT	ENST00000559468.1	-	0	266																											gtttaaattcttttttttttt	0.408													3	3	---	---	---	---					
RP11-66B24.5	0	broad.mit.edu	37	15	101326460	101326461	+	RNA	DEL	GT	GT	-	rs35354528		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr15:101326460_101326461delGT	ENST00000559755.1	+	0	123																											atgtgtatgagtgtgtgtgtca	0.421													2	4	---	---	---	---					
ABCA17P	650655	broad.mit.edu	37	16	2417444	2417444	+	RNA	DEL	A	A	-	rs75997339		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:2417444delA	ENST00000469908.1	+	0	828					NR_003574.1																						actccgtctcaaaaaaaaaaa	0.468													2	4	---	---	---	---					
NAA60	79903	broad.mit.edu	37	16	3431490	3431491	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:3431490_3431491insA	ENST00000575785.1	+	0	71																											gaccctgtctcaaaaaataata	0.475													2	4	---	---	---	---					
RP11-279O17.3	0	broad.mit.edu	37	16	8406858	8406859	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:8406858_8406859insG	ENST00000564185.1	+	0	363																											gtcaaaaaaaaaaaataacaga	0.332													4	2	---	---	---	---					
RP11-57A19.2	0	broad.mit.edu	37	16	28303287	28303288	+	RNA	INS	-	-	ATGG	rs140535903	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:28303287_28303288insATGG	ENST00000501520.1	-	0	97_98																											AAATAggatgcatggatggatg	0.540													4	2	---	---	---	---					
RP11-1166P10.6	0	broad.mit.edu	37	16	32094099	32094099	+	RNA	DEL	T	T	-	rs147968620		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:32094099delT	ENST00000566806.1	-	0	499																											TAAATGACAATGAATTTTTTT	0.388													3	3	---	---	---	---					
LOC101927250	101927250	broad.mit.edu	37	16	50153766	50153767	+	RNA	DEL	AA	AA	-	rs112272955		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:50153766_50153767delAA	ENST00000566770.1	-	0	125																											agaaagaaagaaaaagaaagaa	0.332													4	2	---	---	---	---					
CASC16	643714	broad.mit.edu	37	16	52606306	52606307	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:52606306_52606307insT	ENST00000510238.3	-	0	564					NR_033920.1																						TTCTTGGTTTCTTTTTTTTTCC	0.376													3	4	---	---	---	---					
LOC102724084	102724084	broad.mit.edu	37	16	80317942	80317942	+	RNA	DEL	C	C	-	rs60783349		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr16:80317942delC	ENST00000565050.1	-	0	598				RP11-525K10.3_ENST00000568776.1_RNA|RP11-525K10.3_ENST00000568819.1_RNA																							TTTGATCTGACCCCCCCCAta	0.383													6	1	---	---	---	---					
LINC00670	284034	broad.mit.edu	37	17	12493506	12493507	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:12493506_12493507insA	ENST00000313495.2	+	0	458					NR_034144.1|NR_034145.1																						gactccgtctcaaaaaaaaaaa	0.421													2	4	---	---	---	---					
RP11-47L3.1	0	broad.mit.edu	37	17	33642016	33642017	+	RNA	DEL	CT	CT	-	rs72485204		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:33642016_33642017delCT	ENST00000585387.1	+	0	43																											ccagctctgcctctctctctgt	0.470													3	4	---	---	---	---					
RP11-429O1.1	0	broad.mit.edu	37	17	50504019	50504019	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:50504019delT	ENST00000572848.1	+	0	76																											cccatttttcttttttttgga	0.299													2	4	---	---	---	---					
RP11-101O21.1	0	broad.mit.edu	37	17	72095622	72095623	+	RNA	DEL	CT	CT	-	rs76778762		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:72095622_72095623delCT	ENST00000584003.1	-	0	360																											TCTCTGCACCCTCTCTGAGTCC	0.574													4	4	---	---	---	---					
LOC100294362	100294362	broad.mit.edu	37	17	78373330	78373331	+	RNA	DEL	AA	AA	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr17:78373330_78373331delAA	ENST00000575034.1	-	0	190				CTD-2047H16.4_ENST00000573394.1_RNA|CTD-2047H16.4_ENST00000572151.1_RNA	NR_029376.1																						catcttcaggaaaaaaaaaaag	0.312													2	4	---	---	---	---					
RP11-805F19.2	0	broad.mit.edu	37	18	15087486	15087487	+	RNA	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:15087486_15087487insA	ENST00000583946.1	+	0	113																											aaatttgcaccaaaaaaaaggt	0.450													2	4	---	---	---	---					
LINC00669	647946	broad.mit.edu	37	18	36955918	36955919	+	RNA	INS	-	-	A	rs35738646	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:36955918_36955919insA	ENST00000591629.1	-	0	440					NR_024391.1																						tagctgggactacaggcaaggg	0.515													3	3	---	---	---	---					
LINC00907	284260	broad.mit.edu	37	18	39859748	39859749	+	RNA	INS	-	-	A	rs58791927		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:39859748_39859749insA	ENST00000593234.1	+	0	402					NR_046456.1																						CATGAGAGGTTaaaaaaaaaaa	0.356													3	4	---	---	---	---					
RP11-846C15.2	0	broad.mit.edu	37	18	42732851	42732852	+	RNA	INS	-	-	CTGT	rs147303583	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:42732851_42732852insCTGT	ENST00000589845.1	-	0	290																											CATGTTTTCTCCTGTCTGTATC	0.361													3	5	---	---	---	---					
CTD-2526M8.3	0	broad.mit.edu	37	18	54813669	54813669	+	RNA	DEL	T	T	-	rs34233239		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:54813669delT	ENST00000590942.1	-	0	123																											GATCCAAGGCTTTTGTAGTTT	0.453													6	2	---	---	---	---					
RP11-879F14.1	0	broad.mit.edu	37	18	59282482	59282482	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:59282482delA	ENST00000590968.1	-	0	317																											agtttgtggtaaaaaagccgg	0.423													2	4	---	---	---	---					
SERPINB3	6317	broad.mit.edu	37	18	61324514	61324515	+	Frame_Shift_Ins	INS	-	-	A			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:61324514_61324515insA	ENST00000283752.5	-	6	744_745	c.601_602insT	c.(601-603)gccfs	p.A201fs	SERPINB3_ENST00000332821.8_Frame_Shift_Ins_p.A201fs|SERPINB11_ENST00000489748.1_RNA	NM_006919.2	NP_008850.1	P29508	SPB3_HUMAN	serpin peptidase inhibitor, clade B (ovalbumin), member 3	201					regulation of proteolysis	cytoplasm|extracellular region	protein binding|serine-type endopeptidase inhibitor activity			breast(2)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(4)|lung(14)|ovary(1)|skin(5)|upper_aerodigestive_tract(2)	36						CTTGTTTGGCCAAAATTTTTCC	0.277													18	23	---	---	---	---					
LOC284294	284294	broad.mit.edu	37	18	61841359	61841360	+	RNA	INS	-	-	TCTG	rs67482676	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:61841359_61841360insTCTG	ENST00000589376.1	+	0	200					NR_033881.1																						GCAGTTTTTTTTCTTTTTTTTT	0.347													4	2	---	---	---	---					
LINC01538	400654	broad.mit.edu	37	18	61889400	61889402	+	RNA	DEL	CAA	CAA	-	rs74171707		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:61889400_61889402delCAA	ENST00000588074.1	-	0	443				RP11-146N18.1_ENST00000589376.1_lincRNA	NR_033983.1																						aactctgtctcaacaacaacaaa	0.512													4	5	---	---	---	---					
LINC01538	400654	broad.mit.edu	37	18	61917232	61917233	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:61917232_61917233insG	ENST00000588074.1	-	0	443				RP11-146N18.1_ENST00000589376.1_lincRNA	NR_033983.1																						GTTTCACTGTTGGGGGGTTATT	0.327													2	4	---	---	---	---					
LOC643542	643542	broad.mit.edu	37	18	65326886	65326887	+	RNA	DEL	TG	TG	-	rs3073991		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:65326886_65326887delTG	ENST00000583687.1	+	0	204					NR_033921.1																						ACTGTCCTTTtgtgtgtgtgtg	0.386													3	3	---	---	---	---					
LOC643542	643542	broad.mit.edu	37	18	65513411	65513412	+	RNA	INS	-	-	TGGGAAAGG	rs144159816	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:65513411_65513412insTGGGAAAGG	ENST00000583687.1	+	0	381					NR_033921.1																						ccaaagactcttgtgagttgaa	0.540													4	3	---	---	---	---					
RP11-357H3.1	0	broad.mit.edu	37	18	73727370	73727371	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr18:73727370_73727371insC	ENST00000579775.1	-	0	60																											AGTGCTCAACACCCCCCCGGAA	0.470													2	4	---	---	---	---					
CTB-70G10.1	0	broad.mit.edu	37	19	28794415	28794415	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr19:28794415delG	ENST00000587777.1	-	0	133																											TCAGAGGGATGGCGGTCCAGG	0.468													2	4	---	---	---	---					
LINC01533	100996665	broad.mit.edu	37	19	32523966	32523967	+	RNA	INS	-	-	T			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr19:32523966_32523967insT	ENST00000588694.1	+	0	113																											TTTAAAGTCTGTTTTTTCATAT	0.312													2	4	---	---	---	---					
ZNF702P	79986	broad.mit.edu	37	19	53472196	53472196	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr19:53472196delT	ENST00000600068.1	-	0	489				ZNF702P_ENST00000270443.4_RNA																							TTTGAAATTATTACCTCAAAA	0.353													2	4	---	---	---	---					
SDCBP2-AS1	100507495	broad.mit.edu	37	20	1310530	1310530	+	RNA	DEL	T	T	-	rs80062628		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr20:1310530delT	ENST00000446423.1	+	0	109					NR_040048.1																						tccaaggtggttttttttttt	0.368													2	4	---	---	---	---					
LOC727993	727993	broad.mit.edu	37	20	1956150	1956150	+	RNA	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr20:1956150delC	ENST00000446562.1	+	0	1216																											TGATGGTGTACGGCGTTGTCG	0.498													2	4	---	---	---	---					
RP11-103J8.1	0	broad.mit.edu	37	20	10746970	10746970	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr20:10746970delA	ENST00000605292.1	+	0	98																											actccatctcaaaaaaaaaaa	0.438													3	2	---	---	---	---					
RP4-610C12.1	0	broad.mit.edu	37	20	29584331	29584333	+	RNA	DEL	ATG	ATG	-	rs61177626		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr20:29584331_29584333delATG	ENST00000432067.1	-	0	288																											ttctacaaaaatgataatagtaa	0.493													5	4	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11036712	11036713	+	RNA	INS	-	-	AA	rs150393967		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr21:11036712_11036713insAA	ENST00000470054.1	-	0	1476									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GTGACTTTAACAAAAAAATAGC	0.337													3	4	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11058603	11058603	+	RNA	DEL	G	G	-	rs57429001		TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chr21:11058603delG	ENST00000470054.1	-	0	324									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		AAAACCTAAAGATTTTTTTTT	0.269													7	4	---	---	---	---					
GS1-519E5.1	0	broad.mit.edu	37	X	9226365	9226365	+	RNA	DEL	T	T	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:9226365delT	ENST00000432442.1	+	0	64																											CGAGGCAGACTTTTTTTTTTC	0.463													2	4	---	---	---	---					
CA5BP1	340591	broad.mit.edu	37	X	15718568	15718568	+	RNA	DEL	G	G	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:15718568delG	ENST00000380334.2	+	0	321																											tctaaatcatgagaaaagaca	0.368													2	4	---	---	---	---					
PTCHD1-AS	100873065	broad.mit.edu	37	X	22542796	22542797	+	RNA	INS	-	-	C			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:22542796_22542797insC	ENST00000455399.1	-	0	312																											cactcttgtcacccaggctgga	0.446													2	4	---	---	---	---					
PTCHD1-AS	100873065	broad.mit.edu	37	X	23003965	23003965	+	RNA	DEL	A	A	-	rs4828950	by1000genomes	TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:23003965delA	ENST00000455399.1	-	0	82																											gtgtcatgggattttttttgt	0.378													2	4	---	---	---	---					
KLHL15	80311	broad.mit.edu	37	X	24006703	24006703	+	Frame_Shift_Del	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:24006703delC	ENST00000328046.8	-	4	1405	c.1150delG	c.(1150-1152)tafs	p.V384fs		NM_030624.2	NP_085127.2	Q96M94	KLH15_HUMAN	kelch-like family member 15	384										autonomic_ganglia(1)|breast(1)|endometrium(8)|kidney(2)|large_intestine(3)|lung(6)|ovary(1)	22						CTGCCTGCTACGGCGTAAATA	0.433													63	50	---	---	---	---					
RP11-342D14.1	0	broad.mit.edu	37	X	45175898	45175898	+	RNA	DEL	A	A	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:45175898delA	ENST00000450527.1	+	0	94				RP11-342D14.1_ENST00000438181.1_RNA																							gaataatctgaaaaaaaaata	0.284													2	4	---	---	---	---					
RP11-348F1.3	0	broad.mit.edu	37	X	51128949	51128950	+	RNA	INS	-	-	G			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:51128949_51128950insG	ENST00000425150.1	-	0	367																											ggggactctgtggggggggttc	0.564													3	4	---	---	---	---					
BCORL1	63035	broad.mit.edu	37	X	129148672	129148672	+	Frame_Shift_Del	DEL	C	C	-			TCGA-17-Z013-01A-01W-0746-08	TCGA-17-Z013-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ee0cbaf2-a0bb-4e58-9e52-5986b5f4f25e	a64e7178-30bb-4304-a9e4-58c9146aceff	g.chrX:129148672delC	ENST00000540052.1	+	3	1968	c.1924delC	c.(1924-1926)ccfs	p.P643fs	BCORL1_ENST00000218147.7_Frame_Shift_Del_p.P643fs|BCORL1_ENST00000359304.2_Frame_Shift_Del_p.P643fs|BCORL1_ENST00000303743.5_Frame_Shift_Del_p.P643fs	NM_021946.4	NP_068765.3	Q5H9F3	BCORL_HUMAN	BCL6 corepressor-like 1	643	Pro-rich.				chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus				breast(4)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(9)|liver(3)|lung(30)|ovary(7)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	75						GCGCAAGACACCCCCCATGCC	0.617													11	49	---	---	---	---					
