Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
BCL9L	283149	broad.mit.edu	37	11	118771997	118771997	+	Missense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr11:118771997G>A	ENST00000334801.3	-	6	3419	c.2455C>T	c.(2455-2457)Cgg>Tgg	p.R819W	BCL9L_ENST00000526143.1_5'UTR	NM_182557.2	NP_872363.1	Q86UU0	BCL9L_HUMAN	B-cell CLL/lymphoma 9-like	819	Met-rich.				negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of epithelial to mesenchymal transition|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent		transcription coactivator activity	p.R819W(2)		NS(3)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(13)|lung(20)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|urinary_tract(2)	56	all_hematologic(175;0.0839)	Medulloblastoma(222;0.0425)|all_hematologic(192;0.103)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;7.66e-05)		GCCCGAACCCGGGCCATCTCC	0.647000													18	46					0	0	0.007413	0	0
SRRT	51593	broad.mit.edu	37	7	100478963	100478963	+	Silent	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr7:100478963G>A	ENST00000388793.4	+	3	400	c.180G>A	c.(178-180)cgG>cgA	p.R60R	SRRT_ENST00000347433.4_Silent_p.R60R|SRRT_ENST00000432932.1_Silent_p.R60R|SRRT_ENST00000457580.2_Silent_p.R60R	NM_001128852.1|NM_015908.5	NP_001122324.1|NP_056992.4	Q9BXP5	SRRT_HUMAN	serrate RNA effector molecule homolog (Arabidopsis)	60	Arg-rich.				cell proliferation|primary miRNA processing|response to arsenic-containing substance	cytoplasm|nucleoplasm	protein binding	p.R60R(1)		breast(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(12)|lung(5)|ovary(3)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	40						ACTATGACCGGAATCGGCGAG	0.592000													17	58					0	0	0.007413	0	0
FGD1	2245	broad.mit.edu	37	X	54497770	54497770	+	Missense_Mutation	SNP	C	C	T			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chrX:54497770C>T	ENST00000375135.3	-	2	1191	c.458G>A	c.(457-459)cGg>cAg	p.R153Q		NM_004463.2	NP_004454.2	P98174	FGD1_HUMAN	FYVE, RhoGEF and PH domain containing 1	153	Pro-rich.				actin cytoskeleton organization|apoptosis|filopodium assembly|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|organ morphogenesis|regulation of Cdc42 GTPase activity|regulation of cell shape|small GTPase mediated signal transduction	cytoskeleton|cytosol|Golgi apparatus|lamellipodium|nucleus|plasma membrane|ruffle	metal ion binding|Rho guanyl-nucleotide exchange factor activity|small GTPase binding	p.R153Q(1)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(10)|lung(8)|ovary(3)|pancreas(1)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	39						GCCCGGTGCCCGCTTCAGTGG	0.627000													10	57					0	0	0.013537	0	0
WASH6P	653440	broad.mit.edu	37	X	155252868	155252868	+	RNA	SNP	T	T	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chrX:155252868T>A	ENST00000285718.7	+	0	819				WASH6P_ENST00000461007.1_RNA														p.P304P(5)									TAGCCGAGCCTCTCAAGGCAG	0.632000													5	8					0	0	0.001168	0	0
PTPRB	5787	broad.mit.edu	37	12	70960397	70960397	+	Missense_Mutation	SNP	G	G	T			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr12:70960397G>T	ENST00000334414.6	-	15	3766	c.3722C>A	c.(3721-3723)gCa>gAa	p.A1241E	PTPRB_ENST00000550358.1_Missense_Mutation_p.A1153E|PTPRB_ENST00000550857.1_Missense_Mutation_p.A933E|PTPRB_ENST00000538708.1_Intron|PTPRB_ENST00000451516.2_Missense_Mutation_p.A933E|PTPRB_ENST00000551525.1_Missense_Mutation_p.A1240E|PTPRB_ENST00000261266.5_Missense_Mutation_p.A1023E	NM_001109754.2	NP_001103224.1	P23467	PTPRB_HUMAN	protein tyrosine phosphatase, receptor type, B	1023	Fibronectin type-III 14.				angiogenesis	integral to plasma membrane	protein binding|transmembrane receptor protein tyrosine phosphatase activity	p.A1023E(6)|p.A1241E(3)		breast(4)|central_nervous_system(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(8)|lung(46)|prostate(4)|skin(18)|upper_aerodigestive_tract(1)|urinary_tract(3)	107	Renal(347;0.236)		GBM - Glioblastoma multiforme(2;2.17e-05)|Lung(24;0.000636)|OV - Ovarian serous cystadenocarcinoma(12;0.00306)|STAD - Stomach adenocarcinoma(21;0.149)			ATATCTTTCTGCCACACCAGC	0.423000													5	92					0.00116845	0.00144518	0.001168	1	0
DHDH	27294	broad.mit.edu	37	19	49445800	49445800	+	Silent	SNP	C	C	T			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr19:49445800C>T	ENST00000221403.2	+	5	763	c.723C>T	c.(721-723)agC>agT	p.S241S	DHDH_ENST00000522614.1_Intron|DHDH_ENST00000523250.1_Silent_p.S102S	NM_014475.3	NP_055290.1	Q9UQ10	DHDH_HUMAN	dihydrodiol dehydrogenase (dimeric)	241					carbohydrate metabolic process		binding|D-xylose 1-dehydrogenase (NADP+) activity|electron carrier activity|NAD(P)+ transhydrogenase activity|trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	p.S241S(1)		central_nervous_system(1)|large_intestine(3)|lung(3)|ovary(1)|soft_tissue(1)	9		all_epithelial(76;5.29e-07)|all_lung(116;1.7e-06)|Lung NSC(112;3.55e-06)|all_neural(266;0.0189)|Ovarian(192;0.0261)		OV - Ovarian serous cystadenocarcinoma(262;0.000158)|all cancers(93;0.000258)|Epithelial(262;0.0173)|GBM - Glioblastoma multiforme(486;0.0179)		CCTCCGTGAGCGGCACCAAGG	0.617000													17	29					0	0	0.004990	0	0
AADACL4	343066	broad.mit.edu	37	1	12726494	12726494	+	Silent	SNP	A	A	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr1:12726494A>G	ENST00000376221.1	+	4	972	c.972A>G	c.(970-972)tcA>tcG	p.S324S		NM_001013630.1	NP_001013652.1	Q5VUY2	ADCL4_HUMAN	arylacetamide deacetylase-like 4	324						integral to membrane	carboxylesterase activity	p.S324S(1)		breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(6)|prostate(1)	17	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.000937)|all_lung(284;0.00122)|Colorectal(325;0.00215)|Breast(348;0.0042)|Myeloproliferative disorder(586;0.0393)|Hepatocellular(190;0.0623)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;6.81e-07)|COAD - Colon adenocarcinoma(227;0.000274)|BRCA - Breast invasive adenocarcinoma(304;0.000311)|Kidney(185;0.00217)|KIRC - Kidney renal clear cell carcinoma(229;0.00579)|STAD - Stomach adenocarcinoma(313;0.00743)|READ - Rectum adenocarcinoma(331;0.0384)		TAGAAAATTCACCCCTGATAG	0.473000													3	121					0	0	0.004672	0	0
SEC31B	25956	broad.mit.edu	37	10	102256138	102256138	+	Silent	SNP	C	C	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr10:102256138C>G	ENST00000370345.3	-	18	2284	c.2187G>C	c.(2185-2187)cgG>cgC	p.R729R		NM_015490.3	NP_056305.1	Q9NQW1	SC31B_HUMAN	SEC31 homolog B (S. cerevisiae)	729					protein transport|vesicle-mediated transport	endoplasmic reticulum membrane|ER to Golgi transport vesicle membrane		p.R729R(1)		NS(1)|breast(2)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(3)|lung(17)|ovary(1)|urinary_tract(1)	36		Colorectal(252;0.117)		Epithelial(162;2.36e-10)|all cancers(201;2.09e-08)		CATGAGGACCCCGCAGTTGCT	0.587000													23	47					0	0	0.002780	0	0
MYOM3	127294	broad.mit.edu	37	1	24397690	24397690	+	Missense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr1:24397690G>A	ENST00000330966.7	-	25	3232	c.3070C>T	c.(3070-3072)Cgg>Tgg	p.R1024W	MYOM3_ENST00000374434.3_Missense_Mutation_p.R1023W|RP11-293P20.4_ENST00000429191.1_RNA|RP11-293P20.2_ENST00000439239.2_RNA|MYOM3_ENST00000329601.7_Missense_Mutation_p.R1023W			Q5VTT5	MYOM3_HUMAN	myomesin 3	1023								p.R1023W(1)		NS(2)|breast(2)|central_nervous_system(1)|endometrium(5)|kidney(6)|large_intestine(3)|lung(40)|ovary(2)|prostate(1)|skin(4)|urinary_tract(2)	68		Colorectal(325;3.55e-05)|Renal(390;0.000703)|Lung NSC(340;0.001)|all_lung(284;0.0014)|Ovarian(437;0.00351)|Breast(348;0.0126)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|OV - Ovarian serous cystadenocarcinoma(117;5.31e-24)|Colorectal(126;7.52e-08)|COAD - Colon adenocarcinoma(152;4.01e-06)|GBM - Glioblastoma multiforme(114;4.36e-06)|BRCA - Breast invasive adenocarcinoma(304;0.00108)|KIRC - Kidney renal clear cell carcinoma(1967;0.00404)|STAD - Stomach adenocarcinoma(196;0.00966)|READ - Rectum adenocarcinoma(331;0.0678)|Lung(427;0.153)		AGCCAAAGCCGCACCTCCCCT	0.552000											OREG0013235	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	23					0	0	0.004672	0	0
F9	2158	broad.mit.edu	37	X	138630558	138630558	+	Missense_Mutation	SNP	A	A	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chrX:138630558A>G	ENST00000218099.2	+	5	435	c.428A>G	c.(427-429)cAg>cGg	p.Q143R	F9_ENST00000394090.2_Missense_Mutation_p.Q105R	NM_000133.3	NP_000124.1	P00740	FA9_HUMAN	coagulation factor IX	143	EGF-like 2.				blood coagulation, extrinsic pathway|blood coagulation, intrinsic pathway|peptidyl-glutamic acid carboxylation|post-translational protein modification|proteolysis	endoplasmic reticulum lumen|extracellular region|Golgi lumen|plasma membrane	calcium ion binding|serine-type endopeptidase activity	p.Q143R(1)		breast(1)|central_nervous_system(2)|endometrium(4)|large_intestine(7)|lung(19)|ovary(1)|skin(1)	35	Acute lymphoblastic leukemia(192;0.000127)				Antihemophilic Factor(DB00025)|Coagulation Factor IX(DB00100)|Heparin(DB01109)|Menadione(DB00170)	AGATGCGAGCAGTTTTGTAAA	0.373000													32	113					0	0	0.012213	0	0
DROSHA	29102	broad.mit.edu	37	5	31526237	31526237	+	Missense_Mutation	SNP	T	T	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr5:31526237T>A	ENST00000511367.2	-	4	1047	c.803A>T	c.(802-804)gAt>gTt	p.D268V	DROSHA_ENST00000442743.1_Missense_Mutation_p.D268V|DROSHA_ENST00000344624.3_Missense_Mutation_p.D268V|DROSHA_ENST00000513349.1_Missense_Mutation_p.D268V	NM_013235.4	NP_037367.3	Q9NRR4	RNC_HUMAN	drosha, ribonuclease type III	268	Arg-rich.				gene silencing by RNA|ribosome biogenesis|RNA processing	nucleolus|nucleoplasm	double-stranded RNA binding|metal ion binding|protein binding|ribonuclease III activity	p.D268V(1)		breast(4)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(19)|lung(33)|ovary(2)|skin(1)	66						TCGGTCATAATCAGATCTGTA	0.582000													19	102					0	0	0.008871	0	0
GSTM3	2947	broad.mit.edu	37	1	110280922	110280922	+	Missense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr1:110280922G>A	ENST00000540225.1	-	5	566	c.256C>T	c.(256-258)Cgc>Tgc	p.R86C	GSTM3_ENST00000361066.2_Missense_Mutation_p.R86C|GSTM3_ENST00000256594.3_Missense_Mutation_p.R86C|GSTM3_ENST00000488824.1_5'UTR|RP4-735C1.4_ENST00000431955.1_RNA			P21266	GSTM3_HUMAN	glutathione S-transferase mu 3 (brain)	86	GST N-terminal.				establishment of blood-nerve barrier|glutathione metabolic process|response to estrogen stimulus	cytoplasm	glutathione transferase activity|identical protein binding	p.R86C(1)		endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(2)|skin(1)	9		all_epithelial(167;1.95e-05)|all_lung(203;0.000135)|Lung NSC(277;0.000269)		Colorectal(144;0.0339)|Lung(183;0.0426)|all cancers(265;0.113)|Epithelial(280;0.125)|COAD - Colon adenocarcinoma(174;0.134)|LUSC - Lung squamous cell carcinoma(189;0.228)	Glutathione(DB00143)	TTGTGCTTGCGAGCGATGTAG	0.517000													20	37					0	0	0.010504	0	0
LINC00264	645528	broad.mit.edu	37	10	26880266	26880266	+	RNA	SNP	G	G	A	rs138111133	by1000genomes	TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr10:26880266G>A	ENST00000412114.1	+	0	501					NR_026793.1																						ACCAAGCCCAGTGGACAGATG	0.443000													4	26					0	0	0.009096	0	0
LRRC2	79442	broad.mit.edu	37	3	46593057	46593057	+	Missense_Mutation	SNP	C	C	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr3:46593057C>A	ENST00000395905.3	-	2	417	c.25G>T	c.(25-27)Gac>Tac	p.D9Y	LRRC2_ENST00000496388.1_Intron|LRRC2_ENST00000296144.3_Missense_Mutation_p.D9Y	NM_024512.4	NP_078788.2	Q9BYS8	LRRC2_HUMAN	leucine rich repeat containing 2	9								p.D9Y(1)		breast(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(3)|lung(9)|ovary(1)|prostate(1)	17		Ovarian(412;0.0563)		OV - Ovarian serous cystadenocarcinoma(275;6.37e-05)|BRCA - Breast invasive adenocarcinoma(193;0.00133)|KIRC - Kidney renal clear cell carcinoma(197;0.0214)|Kidney(197;0.0254)		ACAGAAATGTCGAAGACAACC	0.398000													28	59					1.16021e-09	1.51472e-09	0.007291	1	0
TRAV2	28691	broad.mit.edu	37	14	22180975	22180975	+	RNA	SNP	T	T	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr14:22180975T>A	ENST00000390424.2	+	0	257																											GCAGGGACGATACAACATGAC	0.517000													58	203					0	0	0.014410	0	0
OR4K2	390431	broad.mit.edu	37	14	20344588	20344588	+	Missense_Mutation	SNP	C	C	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr14:20344588C>A	ENST00000298642.2	+	1	198	c.162C>A	c.(160-162)caC>caA	p.H54Q		NM_001005501.1	NP_001005501.1	Q8NGD2	OR4K2_HUMAN	olfactory receptor, family 4, subfamily K, member 2	54					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.H54Q(1)		NS(1)|endometrium(5)|kidney(2)|large_intestine(6)|lung(16)|ovary(2)|skin(9)|upper_aerodigestive_tract(2)	43	all_cancers(95;0.00108)		Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)		TGGACCCTCACCTACACTCTC	0.403000													141	158					2.39329e-74	3.21385e-74	0.014410	1	0
DNER	92737	broad.mit.edu	37	2	230312248	230312248	+	Missense_Mutation	SNP	C	C	T			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr2:230312248C>T	ENST00000341772.4	-	8	1404	c.1270G>A	c.(1270-1272)Gga>Aga	p.G424R		NM_139072.3	NP_620711.3	Q8NFT8	DNER_HUMAN	delta/notch-like EGF repeat containing	424	EGF-like 5.				central nervous system development|endocytosis|neuron migration|Notch signaling pathway|synapse assembly	dendrite|early endosome|integral to membrane|plasma membrane	calcium ion binding|clathrin binding|transmembrane receptor activity	p.G424R(1)		NS(2)|breast(1)|endometrium(7)|kidney(1)|large_intestine(13)|liver(1)|lung(28)|ovary(2)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	63		all_lung(227;0.00413)|Renal(207;0.0113)|Lung NSC(271;0.0211)|all_hematologic(139;0.105)|Acute lymphoblastic leukemia(138;0.175)		Epithelial(121;1.4e-11)|all cancers(144;7.7e-09)|LUSC - Lung squamous cell carcinoma(224;0.034)|Lung(119;0.0375)		CAAGCAGATCCGAAGTATCCT	0.453000													5	21					0	0	0.000602	0	0
ARHGAP4	393	broad.mit.edu	37	X	153173206	153173206	+	Missense_Mutation	SNP	C	C	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chrX:153173206C>G	ENST00000370028.3	-	23	2995	c.2938G>C	c.(2938-2940)Gac>Cac	p.D980H	ARHGAP4_ENST00000393721.1_Missense_Mutation_p.D762H|ARHGAP4_ENST00000370016.1_Missense_Mutation_p.D919H|ARHGAP4_ENST00000350060.5_Missense_Mutation_p.D940H|ARHGAP4_ENST00000537206.1_Missense_Mutation_p.D917H	NM_001164741.1	NP_001158213.1	P98171	RHG04_HUMAN	Rho GTPase activating protein 4	940					apoptosis|cytoskeleton organization|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|Rho protein signal transduction	cytosol|focal adhesion|nucleus	Rho GTPase activator activity|Rho guanyl-nucleotide exchange factor activity|SH3/SH2 adaptor activity	p.D940H(1)|p.D980H(1)		central_nervous_system(2)|endometrium(2)|large_intestine(1)|lung(7)|skin(1)|upper_aerodigestive_tract(1)	14	all_cancers(53;6.72e-15)|all_epithelial(53;3.19e-09)|all_lung(58;3.39e-06)|all_hematologic(71;4.25e-06)|Lung NSC(58;4.7e-06)|Acute lymphoblastic leukemia(192;6.56e-05)					GGGGTCGTGTCTAGGCCCTGG	0.716000													5	45					0	0	0.000602	0	0
CUL4B	8450	broad.mit.edu	37	X	119664014	119664014	+	Silent	SNP	T	T	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chrX:119664014T>A	ENST00000371322.5	-	19	2596	c.2535A>T	c.(2533-2535)acA>acT	p.T845T	CUL4B_ENST00000404115.3_Silent_p.T863T|CUL4B_ENST00000336592.6_Silent_p.T850T	NM_001079872.1	NP_001073341.1	Q13620	CUL4B_HUMAN	cullin 4B	863					cell cycle|DNA repair|ubiquitin-dependent protein catabolic process	Cul4B-RING ubiquitin ligase complex|nucleus	protein binding|ubiquitin protein ligase binding	p.T863T(1)|p.T845T(1)		NS(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(7)|lung(14)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36						TGTGGCTAAGTGTCTTTCTCA	0.358000													72	356					0	0	0.014410	0	0
PPP2R2B	5521	broad.mit.edu	37	5	146030242	146030242	+	Nonsense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr5:146030242G>A	ENST00000394413.3	-	5	1063	c.493C>T	c.(493-495)Cga>Tga	p.R165*	PPP2R2B_ENST00000530902.1_5'UTR|PPP2R2B_ENST00000453001.1_Nonsense_Mutation_p.R165*|PPP2R2B_ENST00000394410.2_Nonsense_Mutation_p.R154*|PPP2R2B_ENST00000508545.2_Nonsense_Mutation_p.R154*|PPP2R2B_ENST00000394409.3_Nonsense_Mutation_p.R223*|PPP2R2B_ENST00000356826.3_Nonsense_Mutation_p.R165*|PPP2R2B_ENST00000504198.1_Nonsense_Mutation_p.R171*|PPP2R2B_ENST00000394414.1_Nonsense_Mutation_p.R231*|PPP2R2B_ENST00000394411.4_Nonsense_Mutation_p.R165*|PPP2R2B_ENST00000336640.6_Nonsense_Mutation_p.R168*			Q00005	2ABB_HUMAN	protein phosphatase 2, regulatory subunit B, beta	165					apoptosis|signal transduction	cytoskeleton|mitochondrial outer membrane|protein phosphatase type 2A complex	protein binding|protein phosphatase type 2A regulator activity	p.R168*(1)|p.R223*(1)|p.R165*(1)|p.R154*(1)		endometrium(3)|kidney(4)|large_intestine(6)|liver(2)|lung(9)|ovary(1)|prostate(4)|skin(3)	32			KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			AATACTCTTCGTGGGGTGGCC	0.478000													6	45					0	0	0.001984	0	0
MYH2	4620	broad.mit.edu	37	17	10436696	10436696	+	Nonsense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr17:10436696G>A	ENST00000245503.5	-	21	2731	c.2347C>T	c.(2347-2349)Cga>Tga	p.R783*	CTC-297N7.7_ENST00000581304.1_RNA|CTC-297N7.7_ENST00000399342.2_RNA|MYH2_ENST00000532183.1_Intron|MYH2_ENST00000397183.2_Nonsense_Mutation_p.R783*|CTC-297N7.7_ENST00000587182.1_RNA	NM_017534.5	NP_060004.3	Q9UKX2	MYH2_HUMAN	myosin, heavy chain 2, skeletal muscle, adult	783	Myosin head-like.				muscle filament sliding	muscle myosin complex|myosin filament|sarcomere	actin binding|ATP binding|calmodulin binding|microfilament motor activity|structural constituent of muscle	p.R783*(1)		NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(16)|lung(99)|ovary(6)|pancreas(4)|prostate(3)|skin(8)|upper_aerodigestive_tract(2)|urinary_tract(4)	176						TTGTCATCTCGCATCTCCTCT	0.488000													24	71					0	0	0.002780	0	0
STAG3	10734	broad.mit.edu	37	7	99796940	99796940	+	Missense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr7:99796940G>A	ENST00000426455.1	+	15	1930	c.1523G>A	c.(1522-1524)cGg>cAg	p.R508Q	STAG3_ENST00000440830.1_3'UTR|STAG3_ENST00000394018.2_Missense_Mutation_p.R450Q|STAG3_ENST00000317296.5_Missense_Mutation_p.R508Q			Q9UJ98	STAG3_HUMAN	stromal antigen 3	508					chromosome segregation|synaptonemal complex assembly	chromosome, centromeric region|meiotic cohesin complex|synaptonemal complex	binding	p.R508Q(1)		breast(1)|central_nervous_system(2)|endometrium(6)|kidney(3)|large_intestine(11)|lung(30)|ovary(5)|prostate(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	66	Lung NSC(181;0.0181)|all_lung(186;0.0284)|Esophageal squamous(72;0.0439)					GCAGGGGCTCGGCTGAAGGAC	0.562000													10	49					0	0	0.010729	0	0
TENM2	57451	broad.mit.edu	37	5	167553836	167553836	+	Missense_Mutation	SNP	G	G	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr5:167553836G>A	ENST00000519204.1	+	11	2042	c.1924G>A	c.(1924-1926)Gca>Aca	p.A642T	CTB-178M22.1_ENST00000517408.1_RNA|TENM2_ENST00000520394.1_Missense_Mutation_p.A531T|TENM2_ENST00000545108.1_Missense_Mutation_p.A763T|TENM2_ENST00000403607.2_Missense_Mutation_p.A596T|TENM2_ENST00000518659.1_Missense_Mutation_p.A763T					teneurin transmembrane protein 2									p.A596T(1)|p.A642T(1)|p.A763T(1)									CTGGACAGGCGCAGCGTGTGA	0.577000													5	19					0	0	0.000602	0	0
ARRB2	409	broad.mit.edu	37	17	4623596	4623596	+	Splice_Site	SNP	T	T	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr17:4623596T>G	ENST00000269260.2	+	12	1234		c.e12+2		ARRB2_ENST00000412477.3_Splice_Site|ARRB2_ENST00000574954.1_Splice_Site|ARRB2_ENST00000571206.1_Splice_Site|ARRB2_ENST00000381488.6_Splice_Site|ARRB2_ENST00000572457.1_Splice_Site|ARRB2_ENST00000575877.1_Splice_Site|ARRB2_ENST00000346341.2_Splice_Site	NM_001257328.1|NM_001257330.1|NM_004313.3	NP_001244257.1|NP_001244259.1|NP_004304.1	P32121	ARRB2_HUMAN	arrestin, beta 2						cell chemotaxis|desensitization of G-protein coupled receptor protein signaling pathway by arrestin|G-protein coupled receptor internalization|negative regulation of natural killer cell mediated cytotoxicity|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein ubiquitination|platelet activation|positive regulation of ERK1 and ERK2 cascade|proteasomal ubiquitin-dependent protein catabolic process|protein transport|protein ubiquitination|transcription from RNA polymerase II promoter|transforming growth factor beta receptor signaling pathway	coated pit|cytoplasmic membrane-bounded vesicle|cytosol|nucleus|plasma membrane	angiotensin receptor binding|ubiquitin protein ligase binding	p.?(1)		large_intestine(1)|liver(2)|lung(3)|prostate(1)	7						TCGAGGCGGGTGAGTGTCATG	0.607000													6	21					0	0	0.002450	0	0
U2AF2	11338	broad.mit.edu	37	19	56166481	56166481	+	Missense_Mutation	SNP	T	T	A			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr19:56166481T>A	ENST00000450554.2	+	1	970	c.11T>A	c.(10-12)tTc>tAc	p.F4Y	U2AF2_ENST00000308924.4_Missense_Mutation_p.F4Y	NM_001012478.1|NM_007279.2	NP_001012496.1|NP_009210.1	P26368	U2AF2_HUMAN	U2 small nuclear RNA auxiliary factor 2	4					mRNA 3'-end processing|mRNA export from nucleus|termination of RNA polymerase II transcription	nucleoplasm|spliceosomal complex	enzyme binding|nucleotide binding|RNA binding	p.F4Y(1)		biliary_tract(1)|central_nervous_system(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(3)|lung(9)|ovary(1)|prostate(1)|urinary_tract(2)	21		Colorectal(82;0.00244)|Ovarian(87;0.133)	BRCA - Breast invasive adenocarcinoma(297;0.18)	GBM - Glioblastoma multiforme(193;0.107)		ATGTCGGACTTCGACGAGTTC	0.692000													4	17					0	0	0.009096	0	0
SMARCA4	6597	broad.mit.edu	37	19	11152224	11152224	+	Missense_Mutation	SNP	A	A	G			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr19:11152224A>G	ENST00000358026.2	+	31	4792	c.4508A>G	c.(4507-4509)aAg>aGg	p.K1503R	SMARCA4_ENST00000444061.3_Missense_Mutation_p.K1438R|SMARCA4_ENST00000450717.3_Missense_Mutation_p.K1441R|SMARCA4_ENST00000429416.3_Missense_Mutation_p.K1471R|SMARCA4_ENST00000413806.3_Missense_Mutation_p.K1441R|SMARCA4_ENST00000589677.1_Missense_Mutation_p.K1441R|SMARCA4_ENST00000541122.2_Missense_Mutation_p.K1441R|SMARCA4_ENST00000590574.1_Missense_Mutation_p.K1438R|SMARCA4_ENST00000344626.4_Missense_Mutation_p.K1471R	NM_001128849.1	NP_001122321.1	P51532	SMCA4_HUMAN	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	1471	Bromo.				chromatin remodeling|negative regulation of androgen receptor signaling pathway|negative regulation of cell growth|negative regulation of S phase of mitotic cell cycle|negative regulation of transcription from RNA polymerase II promoter|nervous system development|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nBAF complex|npBAF complex|nuclear chromatin|SWI/SNF complex|WINAC complex	androgen receptor binding|ATP binding|DNA binding|DNA-dependent ATPase activity|helicase activity|histone acetyl-lysine binding|identical protein binding|p53 binding|protein N-terminus binding|transcription corepressor activity	p.K1503R(1)|p.K1471R(1)|p.?(1)		adrenal_gland(1)|autonomic_ganglia(1)|breast(6)|central_nervous_system(23)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(16)|liver(4)|lung(60)|ovary(10)|pancreas(7)|prostate(3)|skin(8)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	163		all_lung(6;0.0512)|Lung NSC(9;0.0568)				GCCGTGATCAAGTACAAGGAC	0.612000			"""F, N, Mis"""		NSCLC								10	17					0	0	0.008291	0	0
PSME1	5720	broad.mit.edu	37	14	24607425	24607425	+	Missense_Mutation	SNP	G	G	C			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr14:24607425G>C	ENST00000382708.3	+	8	543	c.480G>C	c.(478-480)atG>atC	p.M160I	PSME1_ENST00000559123.1_Start_Codon_SNP_p.M1I|PSME1_ENST00000206451.6_Missense_Mutation_p.M160I|PSME1_ENST00000561435.1_Missense_Mutation_p.M160I	NM_176783.1	NP_788955.1	Q06323	PSME1_HUMAN	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	160					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|G1/S transition of mitotic cell cycle|M/G1 transition of mitotic cell cycle|mRNA metabolic process|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|regulation of apoptosis|regulation of cellular amino acid metabolic process|S phase of mitotic cell cycle|viral reproduction	cytoplasm|proteasome activator complex		p.M160I(1)		endometrium(1)|kidney(1)|large_intestine(1)|lung(1)|ovary(2)|prostate(1)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	11				GBM - Glioblastoma multiforme(265;0.00831)		TTGAGCTGATGACCAGCCTCC	0.502000													15	338					0	0	0.002450	0	0
NUP214	8021	broad.mit.edu	37	9	134070639	134070639	+	Missense_Mutation	SNP	A	A	T			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr9:134070639A>T	ENST00000359428.5	+	28	3823	c.3679A>T	c.(3679-3681)Ata>Tta	p.I1227L	NUP214_ENST00000411637.2_Missense_Mutation_p.I1217L|NUP214_ENST00000465486.2_Intron|NUP214_ENST00000451030.1_Missense_Mutation_p.I1228L|NUP214_ENST00000483497.2_Missense_Mutation_p.I53L			P35658	NU214_HUMAN	nucleoporin 214kDa	1227	11 X 5 AA approximate repeats.|Pro/Ser/Thr-rich.				carbohydrate metabolic process|glucose transport|mRNA metabolic process|protein export from nucleus|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|nuclear pore|nucleoplasm	protein binding	p.I1227L(1)		NS(1)|breast(9)|central_nervous_system(3)|endometrium(13)|kidney(2)|large_intestine(9)|liver(2)|lung(29)|ovary(2)|prostate(3)|skin(7)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	86	all_hematologic(7;0.0028)	Myeloproliferative disorder(178;0.204)		OV - Ovarian serous cystadenocarcinoma(145;3.42e-05)|Epithelial(140;0.000256)		TAATTTTGGGATAATCACACC	0.358000			T	"""DEK, SET, ABL1"""	"""AML, T-ALL"""								38	91					0	0	0.006230	0	0
PDE9A	5152	broad.mit.edu	37	21	44185571	44185571	+	Frame_Shift_Del	DEL	T	T	-			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr21:44185571delT	ENST00000291539.6	+	15	1383	c.1323delT	c.(1321-1323)aafs	p.N441fs	PDE9A_ENST00000328862.6_Frame_Shift_Del_p.N415fs|PDE9A_ENST00000398225.3_Frame_Shift_Del_p.N400fs|PDE9A_ENST00000539837.1_Frame_Shift_Del_p.N313fs|PDE9A_ENST00000398236.3_Frame_Shift_Del_p.N355fs|PDE9A_ENST00000398232.3_Frame_Shift_Del_p.N374fs|PDE9A_ENST00000398234.3_Frame_Shift_Del_p.N340fs|PDE9A_ENST00000335512.4_Frame_Shift_Del_p.N381fs|PDE9A_ENST00000398229.3_Frame_Shift_Del_p.N307fs|PDE9A_ENST00000398227.3_Frame_Shift_Del_p.N281fs|PDE9A_ENST00000349112.3_Frame_Shift_Del_p.N313fs|PDE9A_ENST00000380328.2_Frame_Shift_Del_p.N388fs|PDE9A_ENST00000470987.1_3'UTR|PDE9A_ENST00000335440.6_Frame_Shift_Del_p.N339fs|PDE9A_ENST00000398224.3_Frame_Shift_Del_p.N314fs	NM_002606.2	NP_002597.1	O76083	PDE9A_HUMAN	phosphodiesterase 9A	441	Catalytic (By similarity).				platelet activation|signal transduction	cytosol|endoplasmic reticulum|Golgi apparatus|perinuclear region of cytoplasm|ruffle membrane	3',5'-cyclic-GMP phosphodiesterase activity|metal ion binding|protein binding			breast(1)|endometrium(4)|large_intestine(6)|lung(8)|ovary(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	27						AAATGGAGAATTTTGACTACA	0.488													11	30	---	---	---	---					
TOB2	10766	broad.mit.edu	37	22	41832900	41832915	+	Frame_Shift_Del	DEL	CAGGGAGCTGTCCTGG	CAGGGAGCTGTCCTGG	-			TCGA-55-6543-01A-11D-1753-08	TCGA-55-6543-10A-01D-1753-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac7ab3b3-eb76-4da9-bfb3-82b90c8d79d6	e9484e5a-eafe-46c4-8a65-30f102f6b1f4	g.chr22:41832900_41832915delCAGGGAGCTGTCCTGG	ENST00000327492.3	-	2	1141_1156	c.435_450delCCAGGACAGCTCCCTG	c.(433-450)agfs	p.SQDSSL145fs		NM_016272.3	NP_057356.1	Q14106	TOB2_HUMAN	transducer of ERBB2, 2	145					female gamete generation|negative regulation of cell proliferation	cytoplasm|nucleus		p.L150L(1)		cervix(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(4)|ovary(1)|upper_aerodigestive_tract(1)	10						GGGAGTTGGACAGGGAGCTGTCCTGGCTGCCAATGG	0.616													16	36	---	---	---	---					
