Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CSMD1	64478	broad.mit.edu	37	8	3165842	3165842	+	Nonsense_Mutation	SNP	G	G	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr8:3165842G>T	ENST00000520002.1	-	25	4373	c.3818C>A	c.(3817-3819)tCg>tAg	p.S1273*	CSMD1_ENST00000602723.1_Nonsense_Mutation_p.S1273*|CSMD1_ENST00000400186.3_Nonsense_Mutation_p.S1273*|CSMD1_ENST00000602557.1_Nonsense_Mutation_p.S1273*|CSMD1_ENST00000542608.1_Nonsense_Mutation_p.S1272*|CSMD1_ENST00000539096.1_Nonsense_Mutation_p.S1272*|CSMD1_ENST00000537824.1_Nonsense_Mutation_p.S1272*			Q96PZ7	CSMD1_HUMAN	CUB and Sushi multiple domains 1	1273	Sushi 7.					integral to membrane				breast(20)|large_intestine(5)	25		all_cancers(1;5.7e-41)|all_epithelial(1;2.54e-36)|Lung NSC(1;7.54e-11)|all_lung(1;3.2e-10)|Hepatocellular(1;3.78e-05)|Breast(1;0.000196)|Myeloproliferative disorder(4;0.000374)|Esophageal squamous(1;0.0157)|Ovarian(12;0.091)|Renal(68;0.144)|Colorectal(14;0.234)		all cancers(1;5.03e-41)|Epithelial(1;4.78e-31)|Lung(1;1.14e-14)|LUSC - Lung squamous cell carcinoma(1;2.34e-14)|GBM - Glioblastoma multiforme(1;4.49e-10)|Colorectal(4;1.18e-07)|OV - Ovarian serous cystadenocarcinoma(1;3.2e-07)|BRCA - Breast invasive adenocarcinoma(1;6.17e-07)|COAD - Colon adenocarcinoma(4;0.000539)|READ - Rectum adenocarcinoma(4;0.00896)|Kidney(5;0.00957)|KIRC - Kidney renal clear cell carcinoma(5;0.0689)		ACCTATGCACGAAGGTAGTGG	0.507000													3	33					0.115264	0.119106	1	1	0
FLG	2312	broad.mit.edu	37	1	152284472	152284472	+	Missense_Mutation	SNP	C	C	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:152284472C>T	ENST00000368799.1	-	3	2925	c.2890G>A	c.(2890-2892)Ggg>Agg	p.G964R	FLG-AS1_ENST00000593011.1_RNA|FLG-AS1_ENST00000420707.1_RNA	NM_002016.1	NP_002007.1	P20930	FILA_HUMAN	filaggrin	964	Ser-rich.				keratinocyte differentiation	cytoplasmic membrane-bounded vesicle|intermediate filament	calcium ion binding|structural molecule activity			autonomic_ganglia(1)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(38)|haematopoietic_and_lymphoid_tissue(1)|kidney(16)|large_intestine(57)|lung(211)|ovary(13)|pancreas(1)|prostate(15)|skin(24)|stomach(5)|upper_aerodigestive_tract(10)|urinary_tract(12)	424	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			GAAGCAGACCCAGACCACCTC	0.582000									Ichthyosis				19	458					0	0	1	0	0
ABCF3	55324	broad.mit.edu	37	3	183908909	183908909	+	Splice_Site	SNP	A	A	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr3:183908909A>T	ENST00000429586.2	+	16	1621		c.e16-1		EIF2B5_ENST00000444495.1_Intron|ABCF3_ENST00000292808.5_Splice_Site	NM_018358.2	NP_060828.2	Q9NUQ8	ABCF3_HUMAN	ATP-binding cassette, sub-family F (GCN20), member 3								ATP binding|ATPase activity			breast(2)|cervix(1)|endometrium(2)|large_intestine(5)|lung(20)|ovary(3)|prostate(5)|upper_aerodigestive_tract(1)	39	all_cancers(143;1.12e-10)|Ovarian(172;0.0339)		Epithelial(37;2.35e-34)|OV - Ovarian serous cystadenocarcinoma(80;2.72e-22)			TACCTCCTGCAGGTTCCCTGA	0.547000													6	121					0	0	1	0	0
OR10J3	441911	broad.mit.edu	37	1	159284148	159284148	+	Missense_Mutation	SNP	T	T	G			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:159284148T>G	ENST00000332217.5	-	1	301	c.302A>C	c.(301-303)cAg>cCg	p.Q101P		NM_001004467.1	NP_001004467.1	Q5JRS4	O10J3_HUMAN	olfactory receptor, family 10, subfamily J, member 3	101					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)|endometrium(7)|kidney(4)|large_intestine(7)|lung(19)|ovary(3)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	47	all_hematologic(112;0.0429)					GAAGAAGAGCTGAGTGGCACA	0.502000													5	92					0	0	1	0	0
KRTAP4-11	653240	broad.mit.edu	37	17	39274087	39274087	+	Missense_Mutation	SNP	G	G	C	rs141357429	by1000genomes	TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr17:39274087G>C	ENST00000391413.2	-	1	519	c.481C>G	c.(481-483)Ctg>Gtg	p.L161V		NM_033059.3	NP_149048.2	Q9BYQ6	KR411_HUMAN	keratin associated protein 4-11	161	27 X 5 AA repeats of C-C-[GIKRQVHEL]- [SPTR]-[STVQRMC].					keratin filament		p.L161V(1)		endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|lung(8)|prostate(5)|skin(1)	33		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000371)			ACTGGACGCAGGcagcagcag	0.657000													3	16					0	0	1	0	0
ATP1A2	477	broad.mit.edu	37	1	160098487	160098487	+	Missense_Mutation	SNP	C	C	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:160098487C>A	ENST00000361216.3	+	9	1152	c.1063C>A	c.(1063-1065)Ctg>Atg	p.L355M	ATP1A2_ENST00000472488.1_3'UTR|ATP1A2_ENST00000392233.3_Missense_Mutation_p.L355M	NM_000702.3	NP_000693.1	P50993	AT1A2_HUMAN	ATPase, Na+/K+ transporting, alpha 2 polypeptide	355					ATP biosynthetic process		ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|lung(30)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	69	all_cancers(52;1.11e-16)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)|LUSC - Lung squamous cell carcinoma(543;0.246)			GAAGAACTGCCTGGTGAAGAA	0.592000													7	137					0.00621372	0.00713427	1	1	0
ELOVL3	83401	broad.mit.edu	37	10	103988882	103988882	+	Missense_Mutation	SNP	G	G	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr10:103988882G>A	ENST00000370005.3	+	4	907	c.686G>A	c.(685-687)tGc>tAc	p.C229Y		NM_152310.1	NP_689523.1	Q9HB03	ELOV3_HUMAN	ELOVL fatty acid elongase 3	229					fatty acid elongation, monounsaturated fatty acid|fatty acid elongation, polyunsaturated fatty acid|fatty acid elongation, saturated fatty acid|long-chain fatty-acyl-CoA biosynthetic process|triglyceride biosynthetic process|very long-chain fatty acid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	fatty acid elongase activity|protein binding			breast(2)|lung(10)|ovary(2)|prostate(1)|skin(1)	16		Colorectal(252;0.207)		Epithelial(162;4.47e-08)|all cancers(201;7.96e-07)		GATCAGGGATGCCACACCACG	0.502000													5	72					0	0	1	0	0
TUBB8P7	197331	broad.mit.edu	37	16	90161618	90161618	+	RNA	SNP	C	C	T	rs13338202	by1000genomes	TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr16:90161618C>T	ENST00000564451.1	+	0	971				TUBB8P7_ENST00000567960.1_RNA														p.D118D(2)									CAGTGATGGACGTTGTCAGAA	0.607000													4	39					0	0	1	0	0
OBSCN	84033	broad.mit.edu	37	1	228470829	228470829	+	Missense_Mutation	SNP	A	A	G			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:228470829A>G	ENST00000570156.2	+	37	9942	c.9868A>G	c.(9868-9870)Aag>Gag	p.K3290E	OBSCN_ENST00000284548.11_Missense_Mutation_p.K2861E|OBSCN_ENST00000359599.6_Missense_Mutation_p.K1708E|OBSCN_ENST00000366709.4_5'UTR|OBSCN_ENST00000422127.1_Missense_Mutation_p.K2861E|OBSCN_ENST00000366707.4_5'UTR	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	2324	Ig-like 33.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				GCACTGGCTGAAGGACAGGAA	0.662000													2	8					0	0	1	0	0
PPP1R26	9858	broad.mit.edu	37	9	138376538	138376538	+	Missense_Mutation	SNP	G	G	A	rs142346595	byFrequency	TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr9:138376538G>A	ENST00000356818.2	+	4	731	c.182G>A	c.(181-183)cGg>cAg	p.R61Q	PPP1R26_ENST00000605660.1_Missense_Mutation_p.R61Q|PPP1R26_ENST00000605286.1_Missense_Mutation_p.R61Q|PPP1R26_ENST00000604351.1_Missense_Mutation_p.R61Q|PPP1R26_ENST00000602993.1_Intron|PPP1R26_ENST00000401470.3_Missense_Mutation_p.R61Q	NM_014811.3	NP_055626.3	Q5T8A7	K0649_HUMAN	protein phosphatase 1, regulatory subunit 26	61						nucleolus	protein binding										GGGGCTGCTCGGGGCACCAGC	0.711000													5	91					0	0	1	0	0
PRUNE2	158471	broad.mit.edu	37	9	79324593	79324593	+	Missense_Mutation	SNP	C	C	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr9:79324593C>A	ENST00000428286.1	-	8	2720	c.1520G>T	c.(1519-1521)gGc>gTc	p.G507V	PRUNE2_ENST00000376718.3_Missense_Mutation_p.G866V			Q8WUY3	PRUN2_HUMAN	prune homolog 2 (Drosophila)	866					apoptosis|G1 phase|induction of apoptosis	cytoplasm	metal ion binding|pyrophosphatase activity			endometrium(1)|kidney(4)|large_intestine(3)|lung(7)|prostate(1)	16						GTTTTTCTTGCCCCAGATTTC	0.443000													5	63					0.014758	0.0157758	1	1	0
TTC16	158248	broad.mit.edu	37	9	130487173	130487173	+	Missense_Mutation	SNP	G	G	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr9:130487173G>A	ENST00000373289.3	+	9	1336	c.1256G>A	c.(1255-1257)cGc>cAc	p.R419H	TTC16_ENST00000489226.1_Intron|TTC16_ENST00000393748.4_3'UTR	NM_144965.1	NP_659402.1	Q8NEE8	TTC16_HUMAN	tetratricopeptide repeat domain 16	419							binding			central_nervous_system(2)|endometrium(3)|lung(7)|ovary(3)|pancreas(2)|prostate(4)|skin(1)	22						GAGCAGAGGCGCAAGTGCGTG	0.706000													3	6					0	0	1	0	0
RPRD2	23248	broad.mit.edu	37	1	150445766	150445766	+	Missense_Mutation	SNP	C	C	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:150445766C>T	ENST00000401000.4	+	10	4329	c.4264C>T	c.(4264-4266)Ccg>Tcg	p.P1422S	RPRD2_ENST00000369068.4_Missense_Mutation_p.P1448S|RPRD2_ENST00000492220.1_3'UTR			Q5VT52	RPRD2_HUMAN	regulation of nuclear pre-mRNA domain containing 2	1448	Pro-rich.						protein binding			central_nervous_system(1)|endometrium(2)|kidney(4)|large_intestine(4)|lung(20)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	37						TAGGGGCCCTCCGTTCTTTGC	0.512000													6	108					0	0	1	0	0
RAD50	10111	broad.mit.edu	37	5	131895009	131895009	+	Missense_Mutation	SNP	G	G	C			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr5:131895009G>C	ENST00000265335.6	+	2	550	c.163G>C	c.(163-165)Gga>Cga	p.G55R	RAD50_ENST00000378823.3_5'UTR			Q92878	RAD50_HUMAN	RAD50 homolog (S. cerevisiae)	55					DNA duplex unwinding|double-strand break repair via homologous recombination|positive regulation of kinase activity|positive regulation of protein autophosphorylation|reciprocal meiotic recombination|regulation of mitotic recombination|telomere maintenance via telomerase	Mre11 complex|nuclear chromosome, telomeric region|nucleoplasm	ATP binding|DNA binding|nuclease activity|protein binding, bridging|zinc ion binding			breast(3)|cervix(1)|endometrium(4)|kidney(3)|large_intestine(10)|liver(1)|lung(8)|ovary(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	36		all_cancers(142;0.0368)|Breast(839;0.198)	KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)			TATTTGTACTGGAGATTTCCC	0.279000								Homologous recombination					5	100					0	0	1	0	0
ARAP1	116985	broad.mit.edu	37	11	72410538	72410538	+	Missense_Mutation	SNP	G	G	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr11:72410538G>A	ENST00000359373.5	-	17	3213	c.2362C>T	c.(2362-2364)Cgg>Tgg	p.R788W	ARAP1_ENST00000393605.3_Missense_Mutation_p.R548W|ARAP1_ENST00000495878.1_5'UTR|ARAP1_ENST00000393609.3_Missense_Mutation_p.R788W|ARAP1_ENST00000429686.1_Missense_Mutation_p.R482W|ARAP1_ENST00000455638.2_Missense_Mutation_p.R788W|ARAP1_ENST00000426523.1_Missense_Mutation_p.R543W|ARAP1_ENST00000334211.8_Missense_Mutation_p.R543W			Q96P48	ARAP1_HUMAN	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	788	PH 3.				actin filament reorganization involved in cell cycle|negative regulation of stress fiber assembly|positive regulation of Cdc42 GTPase activity|positive regulation of filopodium assembly|regulation of ARF GTPase activity|regulation of cell shape|regulation of cellular component movement|small GTPase mediated signal transduction	cytosol|Golgi cisterna membrane|plasma membrane	ARF GTPase activator activity|phosphatidylinositol-3,4,5-trisphosphate binding|protein binding|Rho GTPase activator activity|zinc ion binding			cervix(2)|endometrium(2)|large_intestine(10)|lung(8)|ovary(1)|skin(3)|urinary_tract(1)	27						GTCACTGCCCGCTCATTCTCA	0.617000													3	22					0	0	1	0	0
LMX1A	4009	broad.mit.edu	37	1	165175207	165175207	+	Silent	SNP	G	G	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:165175207G>T	ENST00000342310.3	-	8	1264	c.882C>A	c.(880-882)ccC>ccA	p.P294P	LMX1A_ENST00000294816.2_Silent_p.P294P|LMX1A_ENST00000367893.4_Silent_p.P294P|LMX1A_ENST00000489443.2_5'UTR	NM_177398.3	NP_796372.1	Q8TE12	LMX1A_HUMAN	LIM homeobox transcription factor 1, alpha	294						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(2)|biliary_tract(1)|central_nervous_system(3)|cervix(2)|endometrium(4)|large_intestine(6)|lung(10)|pancreas(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(4)	35	all_hematologic(923;0.248)					GCTGTGGGGTGGGCAGAGCCG	0.582000													5	93					1.23904e-05	1.53641e-05	1	1	0
GLB1	2720	broad.mit.edu	37	3	33063137	33063137	+	Missense_Mutation	SNP	A	A	C			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr3:33063137A>C	ENST00000307363.5	-	12	1298	c.1154T>G	c.(1153-1155)gTg>gGg	p.V385G	GLB1_ENST00000497796.1_5'UTR|GLB1_ENST00000445488.2_Missense_Mutation_p.V433G|GLB1_ENST00000399402.3_Missense_Mutation_p.V355G|GLB1_ENST00000307377.8_Missense_Mutation_p.V254G	NM_000404.2	NP_000395.2	P16278	BGAL_HUMAN	galactosidase, beta 1	385					carbohydrate metabolic process	lysosome|perinuclear region of cytoplasm	beta-galactosidase activity|cation binding|protein binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(4)|large_intestine(6)|lung(3)|ovary(1)|skin(1)|urinary_tract(1)	21		Melanoma(143;0.104)				AGCTGCTCCCACTGTCTTTAA	0.453000													3	32					0	0	1	0	0
PRUNE2	158471	broad.mit.edu	37	9	79324594	79324594	+	Missense_Mutation	SNP	C	C	A			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr9:79324594C>A	ENST00000428286.1	-	8	2719	c.1519G>T	c.(1519-1521)Ggc>Tgc	p.G507C	PRUNE2_ENST00000376718.3_Missense_Mutation_p.G866C			Q8WUY3	PRUN2_HUMAN	prune homolog 2 (Drosophila)	866					apoptosis|G1 phase|induction of apoptosis	cytoplasm	metal ion binding|pyrophosphatase activity			endometrium(1)|kidney(4)|large_intestine(3)|lung(7)|prostate(1)	16						TTTTTCTTGCCCCAGATTTCT	0.443000													5	62					0.014758	0.0157758	1	1	0
ANKHD1	54882	broad.mit.edu	37	5	139918961	139918961	+	Missense_Mutation	SNP	G	G	C	rs145256820		TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr5:139918961G>C	ENST00000360839.2	+	34	7741	c.7587G>C	c.(7585-7587)tgG>tgC	p.W2529C	ANKHD1-EIF4EBP3_ENST00000532219.1_Intron|ANKHD1_ENST00000544120.1_Missense_Mutation_p.W853C|ANKHD1_ENST00000297183.6_Intron	NM_017747.2	NP_060217.1			ankyrin repeat and KH domain containing 1											breast(2)|endometrium(8)|kidney(6)|large_intestine(14)|lung(18)|ovary(5)|prostate(2)|skin(3)|urinary_tract(2)	60			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			CTGGCACGTGGGCACCTCATA	0.363000													7	181					0	0	1	0	0
HIST2H2BB	338391	broad.mit.edu	37	1	149377834	149377839	+	RNA	DEL	TCTTTG	TCTTTG	-			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr1:149377834_149377839delTCTTTG	ENST00000415338.1	-	0	1061																											GTATCTCTTCTCTTTGTCTTTTTCTG	0.461													3	6	---	---	---	---					
CLIP1	6249	broad.mit.edu	37	12	122812690	122812691	+	Frame_Shift_Ins	INS	-	-	T			TCGA-78-8648-01A-11D-2393-08	TCGA-78-8648-10A-01D-2393-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9116cc35-e986-4e62-a029-8eab48a079e8	eac3d6f3-4ab3-4394-9771-8b3d102d13a9	g.chr12:122812690_122812691insT	ENST00000358808.2	-	16	3173_3174	c.3019_3020insA	c.(3019-3021)ccafs	p.P1007fs	CLIP1_ENST00000545889.1_Frame_Shift_Ins_p.P593fs|CLIP1_ENST00000302528.7_Frame_Shift_Ins_p.P1007fs|CLIP1_ENST00000540338.1_Frame_Shift_Ins_p.P1018fs|CLIP1_ENST00000537178.1_Frame_Shift_Ins_p.P972fs|CLIP1_ENST00000361654.4_Frame_Shift_Ins_p.P896fs	NM_001247997.1|NM_002956.2	NP_001234926.1|NP_002947.1	P30622	CLIP1_HUMAN	CAP-GLY domain containing linker protein 1	1018					mitotic prometaphase|positive regulation of microtubule polymerization	centrosome|cytosol|endosome|intermediate filament|kinetochore	nucleic acid binding|protein homodimerization activity|zinc ion binding			NS(1)|breast(5)|endometrium(4)|kidney(5)|large_intestine(16)|liver(1)|lung(21)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	60	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.81e-05)|Epithelial(86;6.85e-05)|BRCA - Breast invasive adenocarcinoma(302;0.226)		CTGGTTGTGGCTTGTTTCCATT	0.505													8	227	---	---	---	---					
