Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CCDC150	284992	broad.mit.edu	37	2	197521710	197521710	+	Missense_Mutation	SNP	A	A	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr2:197521710A>G	ENST00000389175.4	+	4	561	c.426A>G	c.(424-426)atA>atG	p.I142M	CCDC150_ENST00000272831.7_Intron|CCDC150_ENST00000472405.2_Missense_Mutation_p.I39M|CCDC150_ENST00000423093.2_Intron	NM_001080539.1	NP_001074008.1	Q8NCX0	CC150_HUMAN	coiled-coil domain containing 150	142										breast(3)|endometrium(6)|kidney(1)|large_intestine(6)|lung(14)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	33						TGAATGCAATACAGGAAGAGC	0.453000													7	14					0	0	1	0	0
MOGAT1	116255	broad.mit.edu	37	2	223559867	223559867	+	Missense_Mutation	SNP	A	A	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr2:223559867A>G	ENST00000446656.3	+	5	713	c.713A>G	c.(712-714)aAc>aGc	p.N238S		NM_058165.2	NP_477513.2	Q96PD6	MOGT1_HUMAN	monoacylglycerol O-acyltransferase 1	238					glycerol metabolic process	endoplasmic reticulum membrane|integral to membrane	2-acylglycerol O-acyltransferase activity			breast(1)|cervix(1)|endometrium(1)|lung(5)|urinary_tract(1)	9		Renal(207;0.0183)		Epithelial(121;4.13e-10)|all cancers(144;2.06e-07)|LUSC - Lung squamous cell carcinoma(224;0.00829)|Lung(261;0.0105)		CAAACTGACAACCCTGAAGGA	0.423000													7	24					0	0	1	0	0
RGPD3	653489	broad.mit.edu	37	2	107049631	107049631	+	Silent	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr2:107049631C>T	ENST00000409886.3	-	16	2403	c.2316G>A	c.(2314-2316)gcG>gcA	p.A772A	RGPD3_ENST00000304514.7_Silent_p.A772A	NM_001144013.1	NP_001137485.1	A6NKT7	RGPD3_HUMAN	RANBP2-like and GRIP domain containing 3	772					intracellular transport		binding	p.A772A(4)		breast(2)|central_nervous_system(1)|endometrium(50)|kidney(4)|lung(11)|ovary(1)|urinary_tract(2)	71						TTTCTGAATCCGCATTTCGCA	0.373000													5	184					0	0	1	0	0
GCOM1	0	broad.mit.edu	37	15	57910316	57910316	+	Missense_Mutation	SNP	A	A	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr15:57910316A>T	ENST00000574161.1	+	3	367	c.248A>T	c.(247-249)cAg>cTg	p.Q83L	GCOM1_ENST00000572390.1_Missense_Mutation_p.Q83L|GCOM1_ENST00000587652.1_Missense_Mutation_p.Q83L|GCOM1_ENST00000380568.3_Missense_Mutation_p.Q83L|GCOM1_ENST00000380561.2_Missense_Mutation_p.Q83L|MYZAP_ENST00000267853.5_Missense_Mutation_p.Q83L|MYZAP_ENST00000380565.4_Missense_Mutation_p.Q83L|GCOM1_ENST00000396180.1_Missense_Mutation_p.Q83L|POLR2M_ENST00000380563.2_5'UTR|GCOM1_ENST00000380569.2_Missense_Mutation_p.Q83L|GCOM1_ENST00000380560.2_Missense_Mutation_p.Q83L	NM_001018100.3	NP_001018110.1	P0CAP1	GCOM1_HUMAN		83					intracellular signal transduction	extrinsic to internal side of plasma membrane|I band				endometrium(1)|kidney(2)|large_intestine(9)|liver(1)|lung(1)|ovary(1)|skin(2)|stomach(1)	18						GATCAAAATCAGCAGAAAGAA	0.448000													16	53					0	0	1	0	0
MYH3	4621	broad.mit.edu	37	17	10549033	10549033	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr17:10549033C>T	ENST00000583535.1	-	12	1219	c.1132G>A	c.(1132-1134)Ggc>Agc	p.G378S	MYH3_ENST00000226209.7_Missense_Mutation_p.G378S	NM_002470.3	NP_002461.2	P11055	MYH3_HUMAN	myosin, heavy chain 3, skeletal muscle, embryonic	378	Myosin head-like.				muscle filament sliding|muscle organ development	cytosol|myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|microfilament motor activity			breast(2)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(5)|large_intestine(18)|lung(30)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|upper_aerodigestive_tract(5)|urinary_tract(1)	83						CCTTCTGTGCCATCCGGCTCG	0.527000													9	53					0	0	1	0	0
PBRM1	55193	broad.mit.edu	37	3	52682417	52682417	+	Silent	SNP	T	T	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:52682417T>G	ENST00000356770.4	-	7	758	c.756A>C	c.(754-756)atA>atC	p.I252I	PBRM1_ENST00000409057.1_Silent_p.I252I|PBRM1_ENST00000410007.1_Silent_p.I252I|PBRM1_ENST00000409767.1_Silent_p.I252I|PBRM1_ENST00000409114.3_Silent_p.I252I|PBRM1_ENST00000394830.3_Silent_p.I252I|PBRM1_ENST00000337303.4_Silent_p.I252I|PBRM1_ENST00000296302.7_Silent_p.I252I			Q86U86	PB1_HUMAN	polybromo 1	252	Bromo 2.				chromatin remodeling|mitosis|negative regulation of cell proliferation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nuclear chromosome	chromatin binding|DNA binding|protein binding	p.D251fs*31(3)|p.M248fs*9(2)		breast(5)|endometrium(5)|kidney(301)|liver(1)|lung(22)|pancreas(1)	335				BRCA - Breast invasive adenocarcinoma(193;1.8e-05)|Kidney(197;0.00105)|KIRC - Kidney renal clear cell carcinoma(197;0.00122)|OV - Ovarian serous cystadenocarcinoma(275;0.0613)		CGAGGAGATCTATATCTTTGG	0.338000			"""Mis, N, F, S, D, O"""		"""clear cell renal carcinoma, breast"""								5	65					0	0	1	0	0
ABCD2	225	broad.mit.edu	37	12	40010812	40010812	+	Silent	SNP	A	A	C			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr12:40010812A>C	ENST00000308666.3	-	2	1233	c.1098T>G	c.(1096-1098)acT>acG	p.T366T		NM_005164.3	NP_005155.1	Q9UBJ2	ABCD2_HUMAN	ATP-binding cassette, sub-family D (ALD), member 2	366	ABC transmembrane type-1.				fatty acid metabolic process|transport	ATP-binding cassette (ABC) transporter complex|integral to plasma membrane|peroxisomal membrane	ATP binding|ATPase activity|protein binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(10)|lung(24)|ovary(2)|pancreas(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)	52						AGCCAGTTGCAGTGATAATAG	0.338000													11	95					0	0	1	0	0
CYSLTR1	0	broad.mit.edu	37	X	77528836	77528836	+	Silent	SNP	T	T	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chrX:77528836T>G	ENST00000373304.3	-	3	700	c.408A>C	c.(406-408)acA>acC	p.T136T		NM_006639.2	NP_006630.1	Q9Y271	CLTR1_HUMAN	cysteinyl leukotriene receptor 1	136					elevation of cytosolic calcium ion concentration|respiratory gaseous exchange	integral to plasma membrane|membrane fraction	leukotriene receptor activity			endometrium(2)|kidney(1)|large_intestine(4)|lung(5)|ovary(1)|skin(1)	14					Amlexanox(DB01025)|Cinalukast(DB00587)|Montelukast(DB00471)|Nedocromil(DB00716)|Pranlukast(DB01411)|Zafirlukast(DB00549)	CTTTTTTCTGTGTAACCAAAT	0.363000													14	13					0	0	1	0	0
BEST2	54831	broad.mit.edu	37	19	12864107	12864107	+	Silent	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr19:12864107C>T	ENST00000549706.1	+	3	510	c.186C>T	c.(184-186)ttC>ttT	p.F62F	BEST2_ENST00000042931.1_Silent_p.F62F|BEST2_ENST00000553030.1_Silent_p.F62F			Q8NFU1	BEST2_HUMAN	bestrophin 2	62					membrane depolarization|sensory perception of smell	chloride channel complex|cilium|plasma membrane	chloride channel activity			breast(3)|endometrium(1)|large_intestine(4)|lung(2)|ovary(1)|pancreas(1)	12						AGCGCTACTTCGAGAAGCTTG	0.557000													9	94					0	0	1	0	0
CCDC146	57639	broad.mit.edu	37	7	76888375	76888375	+	Missense_Mutation	SNP	C	C	T	rs141122498	byFrequency	TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr7:76888375C>T	ENST00000285871.4	+	7	875	c.748C>T	c.(748-750)Cgc>Tgc	p.R250C	CCDC146_ENST00000431197.1_5'UTR	NM_020879.2	NP_065930.2	Q8IYE0	CC146_HUMAN	coiled-coil domain containing 146	250										breast(3)|central_nervous_system(3)|endometrium(1)|kidney(4)|large_intestine(7)|lung(10)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|stomach(2)	34		all_cancers(73;0.128)|all_lung(88;0.0986)|all_epithelial(88;0.163)|Myeloproliferative disorder(862;0.205)				AAAAATAACACGCAAAAAAGT	0.348000													8	35					0	0	1	0	0
TRMT44	152992	broad.mit.edu	37	4	8467104	8467104	+	Splice_Site	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr4:8467104G>A	ENST00000389737.4	+	8	1310		c.e8-1		TRMT44_ENST00000513449.2_Splice_Site	NM_152544.2	NP_689757.2			tRNA methyltransferase 44 homolog (S. cerevisiae)																		TCTTTTTGAAGGTCTTCCTAC	0.488000													12	97					0	0	1	0	0
POLR2C	5432	broad.mit.edu	37	16	57496641	57496641	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr16:57496641C>T	ENST00000219252.5	+	1	343	c.5C>T	c.(4-6)cCg>cTg	p.P2L	POLR2C_ENST00000564651.1_3'UTR|AC009052.12_ENST00000567090.1_RNA	NM_032940.2	NP_116558.1	P19387	RPB3_HUMAN	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	2					mRNA capping|nuclear mRNA splicing, via spliceosome|positive regulation of viral transcription|protein phosphorylation|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|transcription-coupled nucleotide-excision repair|viral reproduction	DNA-directed RNA polymerase II, core complex	DNA binding|DNA-directed RNA polymerase activity|protein dimerization activity			breast(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(2)|upper_aerodigestive_tract(1)	10						GGCGAGATGCCGTACGCCAAC	0.652000											OREG0023826	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	3					0	0	1	0	0
OPCML	4978	broad.mit.edu	37	11	132307147	132307147	+	Silent	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr11:132307147G>A	ENST00000331898.7	-	4	1211	c.633C>T	c.(631-633)ccC>ccT	p.P211P	OPCML_ENST00000541867.1_Silent_p.P211P|OPCML_ENST00000529038.1_5'UTR|OPCML_ENST00000374778.4_Silent_p.P170P|OPCML_ENST00000524381.1_Silent_p.P204P	NM_002545.3	NP_002536.1	Q14982	OPCM_HUMAN	opioid binding protein/cell adhesion molecule-like	211	Ig-like C2-type 2.				cell adhesion|neuron recognition	anchored to membrane|integral to plasma membrane	opioid receptor activity			endometrium(5)|kidney(1)|large_intestine(12)|lung(17)|ovary(2)|skin(2)|urinary_tract(8)	47	all_hematologic(175;0.019)	all_cancers(12;5.86e-24)|all_epithelial(12;2.65e-17)|all_lung(97;2.89e-05)|Lung NSC(97;6.16e-05)|Breast(109;0.000126)|Medulloblastoma(222;0.0269)|all_neural(223;0.0326)|Esophageal squamous(93;0.129)		all cancers(11;4.61e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.012)		TCCGCACATCGGGCGCAGCGA	0.537000													4	69					0	0	1	0	0
SPATA31A6	389730	broad.mit.edu	37	9	43627707	43627707	+	Missense_Mutation	SNP	A	A	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr9:43627707A>G	ENST00000332857.6	-	4	1008	c.980T>C	c.(979-981)gTc>gCc	p.V327A		NM_001145196.1	NP_001138668.1			SPATA31 subfamily A, member 6																		TATCCCCACGACATTCTGGCC	0.458000													8	262					0	0	1	0	0
GOLGA6L5	0	broad.mit.edu	37	15	85053124	85053124	+	RNA	SNP	G	G	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr15:85053124G>T	ENST00000414190.2	-	0	328					NR_003246.2																						TAAATGTTTTGTTTTTTTTTT	0.353000													4	7					1	1	1	1	0
GZMH	2999	broad.mit.edu	37	14	25076563	25076563	+	Missense_Mutation	SNP	G	G	C			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr14:25076563G>C	ENST00000216338.4	-	4	433	c.389C>G	c.(388-390)cCt>cGt	p.P130R	RP11-104E19.1_ENST00000557736.1_RNA|RP11-104E19.1_ENST00000555300.1_RNA|GZMH_ENST00000557220.2_Intron|GZMH_ENST00000382548.4_Intron	NM_033423.3	NP_219491.1	P20718	GRAH_HUMAN	granzyme H (cathepsin G-like 2, protein h-CCPX)	130	Peptidase S1.				apoptosis|cytolysis|proteolysis	cytoplasm	serine-type endopeptidase activity			central_nervous_system(1)|endometrium(1)|large_intestine(1)|lung(6)|ovary(1)|prostate(1)|skin(1)	12				GBM - Glioblastoma multiforme(265;0.0267)		CTTGCTGCTAGGTAGCCTGAG	0.582000													6	42					0	0	1	0	0
USP48	84196	broad.mit.edu	37	1	22048218	22048218	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr1:22048218C>T	ENST00000308271.9	-	13	2336	c.1688G>A	c.(1687-1689)cGc>cAc	p.R563H	USP48_ENST00000374732.3_Missense_Mutation_p.R102H|USP48_ENST00000400301.1_Missense_Mutation_p.R563H|USP48_ENST00000529637.1_Missense_Mutation_p.R562H	NM_032236.5	NP_115612.4	Q86UV5	UBP48_HUMAN	ubiquitin specific peptidase 48	563					ubiquitin-dependent protein catabolic process	mitochondrion|nucleus	cysteine-type peptidase activity|ubiquitin thiolesterase activity	p.R563H(1)		NS(1)|endometrium(6)|kidney(2)|large_intestine(11)|lung(14)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	42		Colorectal(325;3.46e-05)|all_lung(284;4.29e-05)|Lung NSC(340;4.66e-05)|Renal(390;0.000219)|Breast(348;0.00222)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0182)|OV - Ovarian serous cystadenocarcinoma(117;4.74e-26)|COAD - Colon adenocarcinoma(152;1.3e-05)|GBM - Glioblastoma multiforme(114;1.86e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000614)|STAD - Stomach adenocarcinoma(196;0.00644)|KIRC - Kidney renal clear cell carcinoma(1967;0.00711)|Lung(427;0.0327)|READ - Rectum adenocarcinoma(331;0.0657)|LUSC - Lung squamous cell carcinoma(448;0.0753)		ACGCAATATGCGACAACGTTC	0.363000													6	57					0	0	1	0	0
MAGEC1	9947	broad.mit.edu	37	X	140994960	140994960	+	Silent	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chrX:140994960G>A	ENST00000285879.4	+	4	2056	c.1770G>A	c.(1768-1770)ctG>ctA	p.L590L	MAGEC1_ENST00000406005.2_Intron	NM_005462.4	NP_005453.2	O60732	MAGC1_HUMAN	melanoma antigen family C, 1	590							protein binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(22)|lung(60)|ovary(1)|pancreas(1)|prostate(1)|skin(7)|stomach(5)|upper_aerodigestive_tract(7)|urinary_tract(1)	127	Acute lymphoblastic leukemia(192;6.56e-05)					AGGACTCCCTGTCTCCTCACT	0.567000										HNSCC(15;0.026)			5	152					0	0	1	0	0
ADAM21P1	0	broad.mit.edu	37	14	70714259	70714259	+	RNA	SNP	A	A	G	rs7144638	by1000genomes	TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr14:70714259A>G	ENST00000530196.1	-	0	259					NR_003951.1																						CACCACTTCCAGGGAAGTGAA	0.527000													4	88					0	0	1	0	0
COL7A1	1294	broad.mit.edu	37	3	48629869	48629869	+	Silent	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:48629869C>T	ENST00000328333.8	-	8	1115	c.1008G>A	c.(1006-1008)caG>caA	p.Q336Q	COL7A1_ENST00000454817.1_Silent_p.Q336Q	NM_000094.3	NP_000085.1	Q02388	CO7A1_HUMAN	collagen, type VII, alpha 1	336	Fibronectin type-III 2.|Nonhelical region (NC1).				cell adhesion|epidermis development	basement membrane|collagen type VII	protein binding|serine-type endopeptidase inhibitor activity			NS(3)|breast(8)|central_nervous_system(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(18)|lung(57)|ovary(7)|prostate(5)|skin(9)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(5)	137				BRCA - Breast invasive adenocarcinoma(193;0.000293)|KIRC - Kidney renal clear cell carcinoma(197;0.00558)|Kidney(197;0.00632)		CTGTGGTATTCTGGATGGTCA	0.627000													9	23					0	0	1	0	0
NEIL1	79661	broad.mit.edu	37	15	75644728	75644728	+	Splice_Site	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr15:75644728G>A	ENST00000564784.1	+	5	1247	c.618_splice	c.e5+1	p.P206_splice	NEIL1_ENST00000569035.1_Splice_Site_p.P206_splice|NEIL1_ENST00000355059.4_Splice_Site_p.P206_splice|NEIL1_ENST00000567959.1_3'UTR			Q96FI4	NEIL1_HUMAN	nei endonuclease VIII-like 1 (E. coli)	206					base-excision repair|negative regulation of nuclease activity|nucleotide-excision repair|response to oxidative stress	cytoplasm|nucleus	damaged DNA binding|DNA-(apurinic or apyrimidinic site) lyase activity|protein C-terminus binding|zinc ion binding			breast(2)|endometrium(2)|large_intestine(4)|lung(4)|ovary(1)	13						AGCACAGGCCGGTAAGCCCAG	0.642000								Base excision repair (BER), DNA glycosylases					3	43					0	0	1	0	0
ALS2CL	259173	broad.mit.edu	37	3	46718435	46718435	+	Missense_Mutation	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:46718435G>A	ENST00000318962.4	-	17	1918	c.1835C>T	c.(1834-1836)gCt>gTt	p.A612V	ALS2CL_ENST00000383742.3_5'UTR|ALS2CL_ENST00000415953.1_Missense_Mutation_p.A612V	NM_147129.3	NP_667340.2	Q60I27	AL2CL_HUMAN	ALS2 C-terminal like	612					endosome organization|regulation of Rho protein signal transduction		GTPase activator activity|identical protein binding|Rho guanyl-nucleotide exchange factor activity			NS(1)|breast(2)|central_nervous_system(3)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(5)|liver(1)|lung(7)|skin(3)|stomach(2)	29				BRCA - Breast invasive adenocarcinoma(193;0.000726)|KIRC - Kidney renal clear cell carcinoma(197;0.0171)|Kidney(197;0.0202)		GGGGCAGCCAGCACACACAAA	0.662000													10	56					0	0	1	0	0
UBBP4	0	broad.mit.edu	37	17	21730916	21730916	+	Missense_Mutation	SNP	G	G	T	rs111245273	by1000genomes	TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr17:21730916G>T	ENST00000584755.1	+	2	615	c.218G>T	c.(217-219)cGg>cTg	p.R73L	UBBP4_ENST00000583708.1_Intron|UBBP4_ENST00000584398.1_Intron|UBBP4_ENST00000578713.1_Missense_Mutation_p.R73L														p.R73L(24)		endometrium(9)|kidney(4)|lung(4)|prostate(3)|urinary_tract(4)	24						GTCCTGCGTCGGAGAGGTGGT	0.552000													4	67					1.23904e-05	1.29804e-05	1	1	0
TIE1	7075	broad.mit.edu	37	1	43783268	43783268	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr1:43783268C>T	ENST00000372476.3	+	16	2733	c.2654C>T	c.(2653-2655)gCg>gTg	p.A885V	TIE1_ENST00000433781.2_Missense_Mutation_p.A530V|TIE1_ENST00000473014.1_3'UTR	NM_001253357.1|NM_005424.4	NP_001240286.1|NP_005415.1	P35590	TIE1_HUMAN	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	885	Protein kinase.				mesoderm development	integral to plasma membrane	ATP binding|protein binding|transmembrane receptor protein tyrosine kinase activity			breast(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(8)|lung(28)|ovary(3)|prostate(2)|salivary_gland(1)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	70	Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)				CGTGACTTTGCGGGAGAACTG	0.502000													6	201					0	0	1	0	0
GPR158	57512	broad.mit.edu	37	10	25887055	25887055	+	Silent	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr10:25887055C>T	ENST00000376351.3	+	11	2859	c.2500C>T	c.(2500-2502)Cta>Tta	p.L834L	GPR158_ENST00000490549.1_3'UTR	NM_020752.2	NP_065803.2	Q5T848	GP158_HUMAN	G protein-coupled receptor 158	834						integral to membrane|plasma membrane	G-protein coupled receptor activity			breast(5)|cervix(1)|endometrium(9)|kidney(10)|large_intestine(20)|lung(56)|ovary(4)|pancreas(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	119						GTCCAGTAGCCTACCCACAGA	0.468000													4	61					0	0	1	0	0
BOD1L1	259282	broad.mit.edu	37	4	13606319	13606319	+	Silent	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr4:13606319C>T	ENST00000040738.5	-	10	2340	c.2205G>A	c.(2203-2205)tcG>tcA	p.S735S		NM_148894.2	NP_683692.2	Q8NFC6	BOD1L_HUMAN	biorientation of chromosomes in cell division 1-like 1	735	Lys-rich.						DNA binding	p.S735S(1)									ATTTGTCTTCCGATGGAGTTT	0.363000													8	43					0	0	1	0	0
NBN	4683	broad.mit.edu	37	8	90955507	90955507	+	Nonsense_Mutation	SNP	C	C	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr8:90955507C>A	ENST00000265433.3	-	14	2312	c.2158G>T	c.(2158-2160)Gaa>Taa	p.E720*	NBN_ENST00000409330.1_Nonsense_Mutation_p.E638*	NM_002485.4	NP_002476.2	O60934	NBN_HUMAN	nibrin	720					cell cycle arrest|DNA damage response, signal transduction by p53 class mediator|DNA duplex unwinding|double-strand break repair via homologous recombination|meiosis|mitotic cell cycle G1/S transition checkpoint|mitotic cell cycle G2/M transition DNA damage checkpoint|positive regulation of kinase activity|positive regulation of protein autophosphorylation|regulation of DNA-dependent DNA replication initiation|telomere maintenance	Mre11 complex|nuclear chromosome, telomeric region|nuclear inclusion body|nucleolus|nucleoplasm	protein N-terminus binding|transcription factor binding			autonomic_ganglia(1)|central_nervous_system(3)|endometrium(4)|kidney(3)|large_intestine(2)|lung(7)|prostate(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	27			BRCA - Breast invasive adenocarcinoma(11;0.0344)			AGCCACTCTTCTAGTTCTGTA	0.418000								Homologous recombination					14	53					2.32078e-09	2.61832e-09	1	1	0
HLA-A	3105	broad.mit.edu	37	6	29910693	29910693	+	Missense_Mutation	SNP	A	A	G	rs41559716	by1000genomes	TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr6:29910693A>G	ENST00000396634.1	+	4	574	c.233A>G	c.(232-234)cAg>cGg	p.Q78R	HLA-A_ENST00000376809.5_Missense_Mutation_p.Q78R|HLA-A_ENST00000376802.2_Missense_Mutation_p.Q78R|HLA-A_ENST00000376806.5_Missense_Mutation_p.Q78R			P30443	1A01_HUMAN	major histocompatibility complex, class I, A	78	Alpha-1.				antigen processing and presentation of peptide antigen via MHC class I|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of immune response|type I interferon-mediated signaling pathway	integral to plasma membrane|MHC class I protein complex	MHC class I receptor activity	p.Q78R(2)		central_nervous_system(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	30						TGGATAGAGCAGGAGGGGCCG	0.657000									Osteosarcoma, Familial Clustering of;Naso-/Oropharyngeal/Laryngeal Cancer, Familial Clustering of;Melanoma, Familial Clustering of;Lichen Sclerosis et Atrophicus, Familial Clustering of	Multiple Myeloma(9;0.094)			5	26					0	0	1	0	0
DFFA	1676	broad.mit.edu	37	1	10523512	10523512	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr1:10523512C>T	ENST00000377038.3	-	4	674	c.607G>A	c.(607-609)Ggc>Agc	p.G203S	DFFA_ENST00000377036.2_Missense_Mutation_p.G203S	NM_004401.2	NP_004392.1	O00273	DFFA_HUMAN	DNA fragmentation factor, 45kDa, alpha polypeptide	203					DNA fragmentation involved in apoptotic nuclear change|intracellular signal transduction|negative regulation of apoptosis	cytosol|mitochondrion|nucleoplasm|plasma membrane	deoxyribonuclease activity|identical protein binding			large_intestine(3)|lung(2)	5	Ovarian(185;0.203)	all_lung(284;1.31e-05)|Lung NSC(185;2.19e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.0228)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;3.25e-07)|COAD - Colon adenocarcinoma(227;7.25e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000296)|Kidney(185;0.00074)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(132;0.0167)|READ - Rectum adenocarcinoma(331;0.0487)		AAGAGGCTGCCCTCTTTCTCC	0.557000													15	59					0	0	1	0	0
RP1-37N7.4	0	broad.mit.edu	37	17	18343741	18343741	+	RNA	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr17:18343741G>A	ENST00000580052.1	+	0	43				KRT16P1_ENST00000581027.1_RNA																							ACCTGGAAGTGAAGATCCGTG	0.587000													3	42					0	0	1	0	0
SMARCC1	6599	broad.mit.edu	37	3	47663719	47663719	+	Missense_Mutation	SNP	A	A	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:47663719A>T	ENST00000254480.5	-	25	2878	c.2759T>A	c.(2758-2760)aTc>aAc	p.I920N	SMARCC1_ENST00000425518.1_5'UTR	NM_003074.3	NP_003065.3	Q92922	SMRC1_HUMAN	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	920					chromatin remodeling|nervous system development|transcription, DNA-dependent	nBAF complex|npBAF complex|nucleoplasm|SWI/SNF complex|WINAC complex	DNA binding|protein N-terminus binding|transcription coactivator activity			breast(1)|endometrium(5)|kidney(2)|large_intestine(3)|lung(15)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	33				BRCA - Breast invasive adenocarcinoma(193;7.47e-05)|KIRC - Kidney renal clear cell carcinoma(197;0.00862)|Kidney(197;0.01)		TCTGTCCATGATAGTTTCCAG	0.353000													28	82					0	0	1	0	0
TRANK1	9881	broad.mit.edu	37	3	36873537	36873537	+	Nonsense_Mutation	SNP	T	T	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:36873537T>A	ENST00000301807.6	-	21	7652	c.5755A>T	c.(5755-5757)Aag>Tag	p.K1919*	TRANK1_ENST00000429976.2_Nonsense_Mutation_p.K2469*|TRANK1_ENST00000428977.2_Nonsense_Mutation_p.K1919*	NM_014831.2	NP_055646.2	O15050	TRNK1_HUMAN	tetratricopeptide repeat and ankyrin repeat containing 1	2469					DNA repair		ATP binding|ATP-dependent DNA helicase activity|DNA binding			NS(2)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(20)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	73						GTCACGTCCTTGGGTTTGTAT	0.483000													18	41					0	0	1	0	0
GRIA1	0	broad.mit.edu	37	5	153056637	153056637	+	Silent	SNP	T	T	G			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr5:153056637T>G	ENST00000285900.5	+	7	1288	c.945T>G	c.(943-945)tcT>tcG	p.S315S	GRIA1_ENST00000518783.1_Silent_p.S325S|GRIA1_ENST00000518142.1_Silent_p.S235S|GRIA1_ENST00000340592.5_Silent_p.S315S|GRIA1_ENST00000448073.4_Silent_p.S325S|GRIA1_ENST00000521843.2_Silent_p.S246S	NM_000827.3|NM_001258019.1	NP_000818.2|NP_001244948.1	P42261	GRIA1_HUMAN	glutamate receptor, ionotropic, AMPA 1	315					synaptic transmission	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|cell junction|dendritic spine|endocytic vesicle membrane|endoplasmic reticulum membrane|neuronal cell body|postsynaptic density|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity|kainate selective glutamate receptor activity|PDZ domain binding			NS(1)|breast(4)|endometrium(7)|kidney(3)|large_intestine(24)|liver(2)|lung(23)|ovary(4)|pancreas(1)|prostate(5)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(2)	81		Medulloblastoma(196;0.0391)|all_neural(177;0.16)|all_hematologic(541;0.21)	Kidney(363;0.000173)|KIRC - Kidney renal clear cell carcinoma(527;0.000785)		Desflurane(DB01189)|Enflurane(DB00228)|Halothane(DB01159)|Isoflurane(DB00753)|L-Glutamic Acid(DB00142)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	TTGATATATCTCGCCGGGGGA	0.567000													4	19					0	0	1	0	0
FMO1	2326	broad.mit.edu	37	1	171250040	171250040	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr1:171250040C>T	ENST00000354841.4	+	5	874	c.743C>T	c.(742-744)cCa>cTa	p.P248L	FMO1_ENST00000367750.3_Missense_Mutation_p.P248L|FMO1_ENST00000469112.1_3'UTR|FMO1_ENST00000402921.2_Missense_Mutation_p.P185L			Q01740	FMO1_HUMAN	flavin containing monooxygenase 1	248					NADPH oxidation|organic acid metabolic process|toxin metabolic process|xenobiotic metabolic process	endoplasmic reticulum lumen|integral to membrane|intrinsic to endoplasmic reticulum membrane|microsome	flavin adenine dinucleotide binding|flavin-containing monooxygenase activity|NADP binding			NS(1)|breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(13)|prostate(2)|skin(2)	27	all_hematologic(923;0.0922)|Acute lymphoblastic leukemia(37;0.181)					AATTCCCTCCCAACCCCAATT	0.463000													5	67					0	0	1	0	0
OTOF	9381	broad.mit.edu	37	2	26705329	26705329	+	Silent	SNP	C	C	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr2:26705329C>A	ENST00000272371.2	-	14	1650	c.1524G>T	c.(1522-1524)gtG>gtT	p.V508V	OTOF_ENST00000403946.3_Silent_p.V508V	NM_194248.2	NP_919224.1	Q9HC10	OTOF_HUMAN	otoferlin	508	C2 2.				cellular membrane fusion|sensory perception of sound|synaptic vesicle exocytosis	basolateral plasma membrane|cell junction|cytosol|endoplasmic reticulum membrane|integral to membrane|membrane fraction|synaptic vesicle membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|breast(9)|central_nervous_system(4)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(14)|lung(35)|ovary(8)|pancreas(1)|prostate(5)|skin(5)|stomach(4)|upper_aerodigestive_tract(3)|urinary_tract(1)	106	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					TGCCGATGGCCACGTCGTTGA	0.587000													5	105					1.024e-07	1.1264e-07	1	1	0
ATP13A5	344905	broad.mit.edu	37	3	193080381	193080381	+	Missense_Mutation	SNP	G	G	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:193080381G>T	ENST00000342358.4	-	4	547	c.430C>A	c.(430-432)Ctg>Atg	p.L144M		NM_198505.2	NP_940907.2	Q4VNC0	AT135_HUMAN	ATPase type 13A5	144					ATP biosynthetic process|cation transport	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|metal ion binding			NS(1)|autonomic_ganglia(2)|breast(1)|endometrium(6)|kidney(4)|large_intestine(15)|liver(2)|lung(26)|ovary(5)|prostate(1)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	76	all_cancers(143;1.08e-08)|Ovarian(172;0.0386)		OV - Ovarian serous cystadenocarcinoma(49;5.56e-18)|LUSC - Lung squamous cell carcinoma(58;6.08e-06)|Lung(62;6.49e-06)	GBM - Glioblastoma multiforme(46;0.000307)		CGCTTCTCCAGGTCGTTCCAA	0.448000													27	132					1.42536e-11	1.65041e-11	1	1	0
LRPAP1	4043	broad.mit.edu	37	4	3526676	3526676	+	Missense_Mutation	SNP	C	C	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr4:3526676C>T	ENST00000500728.2	-	2	453	c.307G>A	c.(307-309)Gaa>Aaa	p.E103K	LRPAP1_ENST00000296325.5_5'UTR	NM_002337.3	NP_002328.1	P30533	AMRP_HUMAN	low density lipoprotein receptor-related protein associated protein 1	103					negative regulation of protein binding|negative regulation of very-low-density lipoprotein particle clearance|protein folding|vesicle-mediated transport	cell surface|integral to membrane|plasma membrane	asialoglycoprotein receptor activity|heparin binding|low-density lipoprotein particle receptor binding|receptor antagonist activity|unfolded protein binding|very-low-density lipoprotein particle receptor binding			breast(1)|endometrium(2)|large_intestine(2)|lung(5)|ovary(1)|prostate(1)|skin(2)	14				UCEC - Uterine corpus endometrioid carcinoma (64;0.165)		TCCCCATCTTCGTCCAAGCCG	0.517000													50	324					0	0	1	0	0
POLQ	10721	broad.mit.edu	37	3	121228543	121228543	+	Silent	SNP	C	C	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr3:121228543C>A	ENST00000264233.5	-	12	1952	c.1824G>T	c.(1822-1824)gtG>gtT	p.V608V		NM_199420.3	NP_955452.3	O75417	DPOLQ_HUMAN	polymerase (DNA directed), theta	608					DNA repair|DNA replication	nucleoplasm	ATP binding|ATP-dependent helicase activity|damaged DNA binding|DNA-directed DNA polymerase activity|single-stranded DNA-dependent ATPase activity			NS(2)|breast(7)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(16)|lung(55)|ovary(5)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)|urinary_tract(2)	120				GBM - Glioblastoma multiforme(114;0.0915)		TTGGATGATACACCTTTCCTG	0.393000								DNA polymerases (catalytic subunits)					14	63					1.3612e-06	1.4608e-06	1	1	0
NAB2	4665	broad.mit.edu	37	12	57485457	57485457	+	Silent	SNP	T	T	C			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr12:57485457T>C	ENST00000300131.3	+	2	1011	c.633T>C	c.(631-633)ccT>ccC	p.P211P	NAB2_ENST00000342556.6_Silent_p.P211P|NAB2_ENST00000357680.4_Silent_p.P211P|NAB2_ENST00000554718.1_3'UTR	NM_005967.3	NP_005958.1	Q15742	NAB2_HUMAN	NGFI-A binding protein 2 (EGR1 binding protein 2)	211					cell proliferation|negative regulation of transcription from RNA polymerase III promoter|transcription, DNA-dependent	nucleus	transcription corepressor activity	p.P211P(3)		breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(6)|lung(5)|ovary(1)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	20						TCTCCCCCCCTGCAGGGGGAG	0.711000													5	24					0	0	1	0	0
CYP2A7	1549	broad.mit.edu	37	19	41387540	41387540	+	Missense_Mutation	SNP	G	G	T	rs112051160		TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr19:41387540G>T	ENST00000301146.4	-	2	838	c.297C>A	c.(295-297)agC>agA	p.S99R	CTC-490E21.12_ENST00000601627.1_Intron|CYP2A7_ENST00000291764.3_Intron	NM_000764.2	NP_000755.2	P20853	CP2A7_HUMAN	cytochrome P450, family 2, subfamily A, polypeptide 7	99						endoplasmic reticulum membrane|microsome	aromatase activity|electron carrier activity|heme binding|oxygen binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(6)|lung(7)|ovary(4)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	27			LUSC - Lung squamous cell carcinoma(20;0.000219)|Lung(22;0.000959)			CGCCTCGCCCGCTGAACTCCT	0.642000													3	33					1	1	1	1	0
TTLL8	164714	broad.mit.edu	37	22	50488626	50488626	+	Silent	SNP	A	A	C			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr22:50488626A>C	ENST00000266182.6	-	2	101	c.102T>G	c.(100-102)gcT>gcG	p.A34A	TTLL8_ENST00000477219.1_5'UTR|TTLL8_ENST00000440475.1_Silent_p.A34A					tubulin tyrosine ligase-like family, member 8											NS(1)|haematopoietic_and_lymphoid_tissue(1)|lung(6)|ovary(4)	12		all_cancers(38;3.44e-07)|all_epithelial(38;2.44e-06)|all_lung(38;0.00141)|Breast(42;0.00519)|Lung NSC(38;0.0199)|Ovarian(80;0.142)|Lung SC(80;0.162)		READ - Rectum adenocarcinoma(2;0.000882)|Colorectal(2;0.00311)|BRCA - Breast invasive adenocarcinoma(115;0.226)		TCCTTCGCAGAGCGGCCCGGA	0.483000													5	14					0	0	1	0	0
PTPN21	11099	broad.mit.edu	37	14	89016642	89016642	+	Silent	SNP	G	G	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr14:89016642G>A	ENST00000556564.1	-	2	404	c.120C>T	c.(118-120)tcC>tcT	p.S40S	PTPN21_ENST00000554628.1_5'UTR|PTPN21_ENST00000328736.3_Silent_p.S40S	NM_007039.3	NP_008970.2	Q16825	PTN21_HUMAN	protein tyrosine phosphatase, non-receptor type 21	40	FERM.					cytoplasm|cytoskeleton	binding|protein tyrosine phosphatase activity			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(13)|liver(1)|lung(7)|ovary(4)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	45						TGCTCTCCACGGACAGGGTGA	0.612000													8	62					0	0	1	0	0
ATP1A3	478	broad.mit.edu	37	19	42471428	42471428	+	Missense_Mutation	SNP	T	T	C			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr19:42471428T>C	ENST00000545399.1	-	22	3178	c.3025A>G	c.(3025-3027)Aaa>Gaa	p.K1009E	ATP1A3_ENST00000302102.5_Missense_Mutation_p.K996E|ATP1A3_ENST00000543770.1_Missense_Mutation_p.K1007E|ATP1A3_ENST00000602133.1_Missense_Mutation_p.K966E	NM_001256214.1	NP_001243143.1	P13637	AT1A3_HUMAN	ATPase, Na+/K+ transporting, alpha 3 polypeptide	996					ATP biosynthetic process	endoplasmic reticulum|Golgi apparatus	ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			NS(1)|breast(2)|endometrium(7)|kidney(2)|large_intestine(11)|liver(1)|lung(19)|ovary(1)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(1)	52						AGGATGAGTTTGCGGATTTCG	0.662000													4	24					0	0	1	0	0
CCT6P1	0	broad.mit.edu	37	7	65226569	65226569	+	RNA	DEL	T	T	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr7:65226569delT	ENST00000442266.1	+	0	1167																											gcccggccCCttttttttttt	0.413													2	4	---	---	---	---					
RP11-1080G15.1	0	broad.mit.edu	37	8	19043038	19043038	+	RNA	DEL	C	C	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr8:19043038delC	ENST00000518417.1	-	0	278																											gaggcaccagccggagattag	0.507													2	4	---	---	---	---					
ZFHX4	79776	broad.mit.edu	37	8	77775449	77775451	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr8:77775449_77775451delCCT	ENST00000521891.2	+	11	9947_9949	c.9499_9501delCCT	c.(9499-9501)del	p.P3173del	ZFHX4_ENST00000050961.6_In_Frame_Del_p.P3124del|ZFHX4_ENST00000455469.2_In_Frame_Del_p.P3128del|ZFHX4_ENST00000518282.1_In_Frame_Del_p.P3147del	NM_024721.4	NP_078997.4	Q86UP3	ZFHX4_HUMAN	zinc finger homeobox 4	3124						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.P3151H(1)		NS(3)|breast(11)|central_nervous_system(1)|endometrium(36)|haematopoietic_and_lymphoid_tissue(2)|kidney(15)|large_intestine(66)|liver(2)|lung(245)|ovary(11)|pancreas(3)|prostate(11)|skin(7)|upper_aerodigestive_tract(13)|urinary_tract(6)	432			BRCA - Breast invasive adenocarcinoma(89;0.0895)			acctccaccacctcctcctcctc	0.522										HNSCC(33;0.089)			3	6	---	---	---	---					
PCF11	51585	broad.mit.edu	37	11	82877721	82877722	+	Frame_Shift_Ins	INS	-	-	A			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr11:82877721_82877722insA	ENST00000298281.4	+	5	2234_2235	c.1782_1783insA	c.(1780-1785)gcaaagfs	p.AK594fs		NM_015885.3	NP_056969.2	O94913	PCF11_HUMAN	PCF11 cleavage and polyadenylation factor subunit	594					mRNA 3'-end processing|mRNA cleavage|nuclear mRNA splicing, via spliceosome|termination of RNA polymerase II transcription	mRNA cleavage factor complex				cervix(1)|endometrium(3)|kidney(4)|large_intestine(1)|lung(22)|ovary(1)|urinary_tract(1)	33						CCAAGTCTGCCAAAAGATGGAA	0.356													13	55	---	---	---	---					
SNHG14	0	broad.mit.edu	37	15	25330470	25330471	+	RNA	INS	-	-	T			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr15:25330470_25330471insT	ENST00000546682.1	+	0	453				SNHG14_ENST00000553108.1_RNA|SNHG14_ENST00000549804.2_RNA	NR_003361.1																						CCTTAGGATGGTAAGTGTCCAT	0.480													16	62	---	---	---	---					
SNHG14	0	broad.mit.edu	37	15	25465467	25465469	+	RNA	DEL	GAA	GAA	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr15:25465467_25465469delGAA	ENST00000424208.1	+	0	3039				SNHG14_ENST00000453082.2_RNA	NR_003305.1																						TGGTGAGACCGAAGAAGACTTGC	0.581													4	6	---	---	---	---					
ZFHX3	463	broad.mit.edu	37	16	72821850	72821850	+	Frame_Shift_Del	DEL	G	G	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr16:72821850delG	ENST00000268489.5	-	10	10997	c.10325delC	c.(10324-10326)cafs	p.P3442fs	ZFHX3_ENST00000397992.5_Frame_Shift_Del_p.P2528fs	NM_006885.3	NP_008816.3	Q15911	ZFHX3_HUMAN	zinc finger homeobox 3	3442					muscle organ development|negative regulation of myoblast differentiation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-dependent|positive regulation of myoblast differentiation	transcription factor complex	enzyme binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|transcription regulatory region DNA binding|zinc ion binding			NS(3)|breast(7)|cervix(2)|endometrium(18)|haematopoietic_and_lymphoid_tissue(5)|kidney(8)|large_intestine(22)|liver(1)|lung(46)|ovary(5)|pancreas(1)|prostate(15)|skin(6)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(11)	153		Ovarian(137;0.13)				TTCTGCTTCTGGCTCTTCAGG	0.562													11	61	---	---	---	---					
CDC27	996	broad.mit.edu	37	17	45219612	45219612	+	Frame_Shift_Del	DEL	A	A	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr17:45219612delA	ENST00000066544.3	-	11	1454	c.1361delT	c.(1360-1362)cafs	p.L454fs	CDC27_ENST00000446365.2_Frame_Shift_Del_p.L393fs|CDC27_ENST00000531206.1_Frame_Shift_Del_p.L460fs|CDC27_ENST00000527547.1_Frame_Shift_Del_p.L454fs	NM_001114091.1|NM_001256.3	NP_001107563.1|NP_001247.3	P30260	CDC27_HUMAN	cell division cycle 27	454					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule	protein phosphatase binding			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2)	90						TGCTTTTTGTAGATTAAAGGC	0.308													8	58	---	---	---	---					
GNAL	2774	broad.mit.edu	37	18	11689860	11689860	+	Frame_Shift_Del	DEL	A	A	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr18:11689860delA	ENST00000334049.6	+	1	906	c.298delA	c.(298-300)aafs	p.K100fs		NM_182978.3	NP_892023.1	P38405	GNAL_HUMAN	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type	23					activation of adenylate cyclase activity by dopamine receptor signaling pathway|inhibition of adenylate cyclase activity by G-protein signaling pathway|sensory perception of smell|synaptic transmission	heterotrimeric G-protein complex	adenylate cyclase activity|G-protein beta/gamma-subunit complex binding|G-protein-coupled receptor binding|GTP binding|GTPase activity|signal transducer activity			central_nervous_system(1)|endometrium(1)|large_intestine(4)|liver(1)|lung(4)|ovary(1)	12						GGAGGCGAGGAAAGTGAGCCG	0.697													2	4	---	---	---	---					
CPLX4	339302	broad.mit.edu	37	18	56985545	56985545	+	Frame_Shift_Del	DEL	C	C	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr18:56985545delC	ENST00000299721.3	-	1	336	c.150delG	c.(148-150)aafs	p.K50fs	CPLX4_ENST00000587244.1_Frame_Shift_Del_p.K50fs	NM_181654.3	NP_857637.1	Q7Z7G2	CPLX4_HUMAN	complexin 4	50					exocytosis|neurotransmitter transport	cell junction|synapse	syntaxin binding			autonomic_ganglia(1)|breast(3)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(3)|ovary(1)|skin(1)	16		Colorectal(73;0.175)				CAATCATTTGCTTTTGATACT	0.408													22	135	---	---	---	---					
FAM207A	85395	broad.mit.edu	37	21	46396598	46396598	+	Frame_Shift_Del	DEL	G	G	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr21:46396598delG	ENST00000291634.6	+	6	621	c.573delG	c.(571-573)gafs	p.E193fs	FAM207A_ENST00000479127.1_3'UTR|FAM207A_ENST00000397826.3_Frame_Shift_Del_p.E178fs	NM_058190.2	NP_478070.1	Q9NSI2	CU070_HUMAN	family with sequence similarity 207, member A	193																	CTTTCAGCGAGGAAGAAAGGA	0.632													2	4	---	---	---	---					
MGC20647	0	broad.mit.edu	37	22	30642384	30642386	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-XK-AAJR-01A-11D-A41K-08	TCGA-XK-AAJR-10A-01D-A41N-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	2ea55808-8cd1-4b76-b8ae-1463d5cf3587	4734b728-d63b-4669-988d-eca6c1abb0f6	g.chr22:30642384_30642386delGAG	ENST00000593843.1	+	2	200_202	c.200_202delGAG	c.(199-204)cga>c	p.RG67del	LIF_ENST00000249075.3_Intron|LIF_ENST00000403987.3_Intron																							TGTCCggagcgaggaggaggagg	0.606													2	4	---	---	---	---					
