Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
GPATCH3	63906	broad.mit.edu	37	1	27223851	27223851	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:27223851A>G	uc001bne.2	-	2	846	c.817T>C	c.(817-819)TGT>CGT	p.C273R	GPATCH3_uc009vsp.1_Missense_Mutation_p.C84R	NM_022078	NP_071361	Q96I76	GPTC3_HUMAN	G patch domain containing 3	273	Glu-rich.					intracellular	nucleic acid binding				0		all_cancers(24;1.29e-21)|all_epithelial(13;2.35e-19)|Colorectal(325;0.000147)|all_lung(284;0.00122)|Lung NSC(340;0.00128)|Breast(348;0.00131)|Renal(390;0.00211)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0707)|all_neural(195;0.0966)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0178)|Epithelial(14;3.97e-51)|OV - Ovarian serous cystadenocarcinoma(117;9.55e-30)|Colorectal(126;5.31e-09)|COAD - Colon adenocarcinoma(152;9.31e-07)|BRCA - Breast invasive adenocarcinoma(304;0.000513)|STAD - Stomach adenocarcinoma(196;0.000595)|KIRC - Kidney renal clear cell carcinoma(1967;0.00072)|READ - Rectum adenocarcinoma(331;0.0419)		GGCTCTCCACAGGGGCTGGCT	0.527000												
ERI3	79033	broad.mit.edu	37	1	44785405	44785405	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:44785405C>T	uc001clt.2	-	4	742	c.501G>A	c.(499-501)GAG>GAA	p.E167E	ERI3_uc010okv.1_5'UTR|ERI3_uc009vxg.2_Silent_p.E167E|ERI3_uc010okw.1_Silent_p.E89E|ERI3_uc001clu.2_Silent_p.E89E	NM_024066	NP_076971	O43414	ERI3_HUMAN	prion protein interacting protein	167	Exonuclease.					intracellular	exonuclease activity|metal ion binding|nucleic acid binding			ovary(2)|large_intestine(1)	3						GGATGGGGAACTCGATGATTT	0.423000												
SPATA1	64173	broad.mit.edu	37	1	84991560	84991560	+	Silent	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:84991560A>G	uc001djz.1	+	6	613	c.414A>G	c.(412-414)GTA>GTG	p.V138V	SPATA1_uc001djx.2_Silent_p.V138V|SPATA1_uc001djy.1_RNA	NM_001081472	NP_001074941			spermatogenesis associated 1											central_nervous_system(1)	1				Epithelial(280;4.36e-10)|all cancers(265;7.1e-09)|BRCA - Breast invasive adenocarcinoma(282;8.45e-09)|OV - Ovarian serous cystadenocarcinoma(397;0.00286)|KIRC - Kidney renal clear cell carcinoma(1967;0.0111)		TGCTTCCTGTAATGGACCATT	0.333000												
ADAM30	11085	broad.mit.edu	37	1	120438121	120438121	+	Missense_Mutation	SNP	T	T	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:120438121T>A	uc001eij.2	-	1	993	c.839A>T	c.(838-840)AAA>ATA	p.K280I		NM_021794	NP_068566	Q9UKF2	ADA30_HUMAN	ADAM metallopeptidase domain 30 preproprotein	280	Peptidase M12B.|Extracellular (Potential).				proteolysis	integral to membrane	metalloendopeptidase activity|zinc ion binding			ovary(2)|lung(1)	3	all_cancers(5;7.07e-10)|all_epithelial(5;1.62e-10)|all_neural(166;0.153)|Breast(55;0.234)	all_lung(203;1.55e-06)|Lung NSC(69;1.04e-05)|all_epithelial(167;0.00138)		Lung(183;0.0204)|LUSC - Lung squamous cell carcinoma(189;0.117)		TACACTTTTTTTATATATTAC	0.343000												
RC3H1	149041	broad.mit.edu	37	1	173931083	173931083	+	Missense_Mutation	SNP	T	T	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:173931083T>C	uc001gju.3	-	11	2069	c.1982A>G	c.(1981-1983)CAG>CGG	p.Q661R	RC3H1_uc010pms.1_Missense_Mutation_p.Q661R|RC3H1_uc001gjv.2_Missense_Mutation_p.Q661R|RC3H1_uc010pmt.1_Missense_Mutation_p.Q661R	NM_172071	NP_742068	Q5TC82	RC3H1_HUMAN	roquin	661	Pro-rich.				cytoplasmic mRNA processing body assembly|negative regulation of activated T cell proliferation|negative regulation of B cell proliferation|negative regulation of germinal center formation|negative regulation of T-helper cell differentiation|nuclear-transcribed mRNA catabolic process|regulation of mRNA stability|regulation of T cell receptor signaling pathway	cytoplasmic mRNA processing body|stress granule	mRNA 3'-UTR binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(2)	2						AGGTGGGTACTGCTGTGGCTG	0.498000												
ACTN2	88	broad.mit.edu	37	1	236902782	236902782	+	Missense_Mutation	SNP	C	C	T	rs1150181		TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:236902782C>T	uc001hyf.2	+	10	1261	c.1057C>T	c.(1057-1059)CGG>TGG	p.R353W	ACTN2_uc001hyg.2_Missense_Mutation_p.R145W|ACTN2_uc009xgi.1_Missense_Mutation_p.R353W|ACTN2_uc010pxu.1_Intron|ACTN2_uc001hyh.2_Missense_Mutation_p.R41W	NM_001103	NP_001094	P35609	ACTN2_HUMAN	actinin, alpha 2	353	Spectrin 1.				focal adhesion assembly|microspike assembly|muscle filament sliding|platelet activation|platelet degranulation|protein homotetramerization|regulation of apoptosis|synaptic transmission	actin filament|cytosol|dendritic spine|extracellular region|filopodium|focal adhesion|nucleolus|platelet alpha granule lumen|pseudopodium|Z disc	actin binding|calcium ion binding|FATZ 1 binding|identical protein binding|integrin binding|protein dimerization activity|structural constituent of muscle|titin binding|titin Z domain binding|ZASP binding			ovary(4)|skin(1)	5	Ovarian(103;0.0634)|Breast(184;0.221)	all_cancers(173;0.00661)|Acute lymphoblastic leukemia(190;0.109)|Prostate(94;0.174)	OV - Ovarian serous cystadenocarcinoma(106;0.00168)			GACCAAGCTGCGGATCAGCAA	0.612000												
OR2L8	391190	broad.mit.edu	37	1	248112505	248112505	+	Missense_Mutation	SNP	T	T	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:248112505T>G	uc001idt.1	+	1	346	c.346T>G	c.(346-348)TCT>GCT	p.S116A	OR2L13_uc001ids.2_Intron	NM_001001963	NP_001001963	Q8NGY9	OR2L8_HUMAN	olfactory receptor, family 2, subfamily L,	116	Helical; Name=3; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(1)|skin(1)	2	all_cancers(71;0.000139)|all_epithelial(71;1.58e-05)|Breast(184;0.0117)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0152)			ACTTTTGGCATCTATGGCCTA	0.438000												
OR2M4	26245	broad.mit.edu	37	1	248402353	248402353	+	Missense_Mutation	SNP	A	A	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr1:248402353A>C	uc010pzh.1	+	1	123	c.123A>C	c.(121-123)GAA>GAC	p.E41D		NM_017504	NP_059974	Q96R27	OR2M4_HUMAN	olfactory receptor, family 2, subfamily M,	41	Helical; Name=1; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)	2	all_cancers(71;0.000124)|all_epithelial(71;1.03e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0245)			CATTGATGGAAAATATTTCCA	0.473000												
ITIH2	3698	broad.mit.edu	37	10	7745363	7745363	+	Translation_Start_Site	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr10:7745363C>G	uc001ijs.2	+	1	128	c.-34C>G	c.(-36--32)ATCTG>ATGTG			NM_002216	NP_002207	P19823	ITIH2_HUMAN	inter-alpha globulin inhibitor H2 polypeptide						hyaluronan metabolic process	extracellular region	serine-type endopeptidase inhibitor activity			ovary(1)|pancreas(1)|skin(1)	3						CCCAGACCATCTGCTTTGGGG	0.418000												
SLC16A9	220963	broad.mit.edu	37	10	61432672	61432672	+	Splice_Site	SNP	C	C	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr10:61432672C>A	uc010qig.1	-	3	646	c.197_splice	c.e3-1	p.S66_splice		NM_194298	NP_919274	Q7RTY1	MOT9_HUMAN	solute carrier family 16 (monocarboxylic acid						urate metabolic process	integral to membrane|plasma membrane	symporter activity			skin(2)|ovary(1)	3						CAGACAGGACCTAAAAAAAGA	0.363000												
SCGB1C1	147199	broad.mit.edu	37	11	193135	193135	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:193135C>T	uc001loa.1	+	1	56	c.36C>T	c.(34-36)CTC>CTT	p.L12L		NM_145651	NP_663626	Q8TD33	SG1C1_HUMAN	secretoglobin, family 1C, member 1 precursor	12						extracellular region	binding			skin(1)	1		all_cancers(49;1.58e-09)|all_epithelial(84;2.71e-06)|Breast(177;0.000162)|Ovarian(85;0.000626)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.0538)|all_lung(207;0.0713)		all cancers(45;3.95e-27)|Epithelial(43;2.66e-26)|OV - Ovarian serous cystadenocarcinoma(40;5.55e-21)|BRCA - Breast invasive adenocarcinoma(625;3.56e-05)|Lung(200;0.105)|LUSC - Lung squamous cell carcinoma(625;0.122)		TGGTGGCCCTCACCCTGTTCT	0.612000												
OR2AG1	144125	broad.mit.edu	37	11	6806527	6806527	+	Missense_Mutation	SNP	C	C	T	rs147955834	byFrequency	TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:6806527C>T	uc001mer.1	+	1	259	c.259C>T	c.(259-261)CGC>TGC	p.R87C		NM_001004489	NP_001004489	Q9H205	O2AG1_HUMAN	olfactory receptor, family 2, subfamily AG,	87	Extracellular (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(1)	1		Medulloblastoma(188;0.00776)|all_neural(188;0.0652)		Epithelial(150;2.19e-08)|BRCA - Breast invasive adenocarcinoma(625;0.129)		GGACTTTCTGCGCAGAGAAAA	0.567000												
SPTY2D1	144108	broad.mit.edu	37	11	18637507	18637507	+	Nonsense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:18637507G>C	uc001moy.2	-	3	530	c.314C>G	c.(313-315)TCA>TGA	p.S105*	SPTY2D1_uc010rdi.1_Nonsense_Mutation_p.S105*	NM_194285	NP_919261	Q68D10	SPT2_HUMAN	SPT2, Suppressor of Ty, domain containing 1	105										breast(1)	1						CCTCTTCTTTGACTTTTCCTC	0.438000												
NUP160	23279	broad.mit.edu	37	11	47819349	47819349	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:47819349G>A	uc001ngm.2	-	27	3356	c.3271C>T	c.(3271-3273)CGC>TGC	p.R1091C	NUP160_uc009ylw.2_RNA	NM_015231	NP_056046	Q12769	NU160_HUMAN	nucleoporin 160kDa	1091					carbohydrate metabolic process|glucose transport|mitotic prometaphase|mRNA export from nucleus|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|Nup107-160 complex	nucleocytoplasmic transporter activity|protein binding			ovary(4)|lung(1)|central_nervous_system(1)|skin(1)	7						TAATTGTGGCGATAGATGTGA	0.413000												
MMP20	9313	broad.mit.edu	37	11	102482570	102482570	+	Missense_Mutation	SNP	G	G	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:102482570G>T	uc001phc.2	-	3	452	c.439C>A	c.(439-441)CAG>AAG	p.Q147K		NM_004771	NP_004762	O60882	MMP20_HUMAN	matrix metalloproteinase 20 preproprotein	147					proteolysis|regulation of enamel mineralization	extracellular space|proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase activity|protein binding|zinc ion binding			urinary_tract(1)|skin(1)	2	all_cancers(8;8.95e-05)|all_epithelial(12;0.00227)|Lung NSC(15;0.139)	Acute lymphoblastic leukemia(157;0.000967)|all_hematologic(158;0.0033)	Epithelial(9;0.0216)|Lung(13;0.0711)|all cancers(10;0.0889)|LUSC - Lung squamous cell carcinoma(19;0.13)	BRCA - Breast invasive adenocarcinoma(274;0.0161)		CTCCAGGCCTGCAAGGCCATC	0.438000												
SIK3	23387	broad.mit.edu	37	11	116719989	116719989	+	Silent	SNP	T	T	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:116719989T>G	uc001ppy.2	-	21	3384	c.3348A>C	c.(3346-3348)ATA>ATC	p.I1116I	SIK3_uc001ppz.2_Silent_p.I955I|SIK3_uc001pqa.2_Silent_p.I1056I|SIK3_uc001ppw.2_Silent_p.I473I|SIK3_uc001ppx.2_Silent_p.I494I	NM_025164	NP_079440	Q9Y2K2	SIK3_HUMAN	serine/threonine-protein kinase QSK	1116						cytoplasm	ATP binding|magnesium ion binding|protein binding|protein serine/threonine kinase activity			ovary(4)|breast(3)|stomach(2)|lung(1)|skin(1)|kidney(1)	12						TGCAGTTCCCTATGACAGGCT	0.552000												
CDON	50937	broad.mit.edu	37	11	125891151	125891151	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:125891151G>A	uc009zbw.2	-	3	469	c.341C>T	c.(340-342)TCT>TTT	p.S114F	CDON_uc001qdc.3_Missense_Mutation_p.S114F|CDON_uc001qdd.3_RNA|CDON_uc009zbx.2_Missense_Mutation_p.S114F	NM_016952	NP_058648	Q4KMG0	CDON_HUMAN	surface glycoprotein, Ig superfamily member	114	Extracellular (Potential).|Ig-like C2-type 1.				cell adhesion|muscle cell differentiation|positive regulation of muscle cell differentiation	integral to membrane|plasma membrane	protein binding			ovary(3)|skin(2)|breast(1)	6	all_hematologic(175;0.177)	Breast(109;0.00157)|Lung NSC(97;0.0127)|all_lung(97;0.0133)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;1.51e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0604)		ACCTGCCACAGATACTGTCGC	0.383000												
OS9	10956	broad.mit.edu	37	12	58114598	58114598	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr12:58114598G>A	uc001spj.2	+	15	1969	c.1910G>A	c.(1909-1911)CGC>CAC	p.R637H	OS9_uc010srx.1_Missense_Mutation_p.R376H|OS9_uc001spk.2_Missense_Mutation_p.R622H|OS9_uc001spl.2_Missense_Mutation_p.R582H|OS9_uc001spm.2_Missense_Mutation_p.R567H|OS9_uc001spn.2_Missense_Mutation_p.R583H|OS9_uc010sry.1_Missense_Mutation_p.R550H|OS9_uc010srz.1_Missense_Mutation_p.R508H	NM_006812	NP_006803	Q13438	OS9_HUMAN	osteosarcoma amplified 9, endoplasmic reticulum	637					ER-associated protein catabolic process|protein retention in ER lumen|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to endoplasmic reticulum stress	endoplasmic reticulum lumen|Hrd1p ubiquitin ligase complex	glycoprotein binding|protein binding|sugar binding			ovary(1)	1	all_neural(12;0.00548)|Glioma(12;0.0126)|Melanoma(17;0.122)		BRCA - Breast invasive adenocarcinoma(9;0.109)			CAGAAGGAACGCCAGCGGCAG	0.637000												
FAM71C	196472	broad.mit.edu	37	12	100042226	100042226	+	Missense_Mutation	SNP	G	G	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr12:100042226G>T	uc001tgn.2	+	1	696	c.274G>T	c.(274-276)GCT>TCT	p.A92S	ANKS1B_uc001tge.1_Intron|ANKS1B_uc001tgf.1_Intron|ANKS1B_uc009ztt.1_Intron	NM_153364	NP_699195	Q8NEG0	FA71C_HUMAN	hypothetical protein LOC196472	92											0				OV - Ovarian serous cystadenocarcinoma(2;0.00733)|Epithelial(2;0.0385)|all cancers(2;0.19)		GGCCCGACCAGCTGCTGTCTG	0.552000												
MED13L	23389	broad.mit.edu	37	12	116424993	116424993	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr12:116424993C>T	uc001tvw.2	-	18	4090	c.4035G>A	c.(4033-4035)AGG>AGA	p.R1345R		NM_015335	NP_056150	Q71F56	MD13L_HUMAN	mediator complex subunit 13-like	1345					regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent					skin(4)|ovary(2)|upper_aerodigestive_tract(1)|lung(1)	8	all_neural(191;0.117)|Medulloblastoma(191;0.163)			BRCA - Breast invasive adenocarcinoma(302;0.0407)		TCTCCCAGGTCCTGCCCGTGC	0.547000												
SOHLH2	54937	broad.mit.edu	37	13	36764191	36764191	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr13:36764191G>C	uc001uvj.2	-	6	622	c.533C>G	c.(532-534)TCT>TGT	p.S178C	SOHLH2_uc010tei.1_Missense_Mutation_p.S255C	NM_017826	NP_060296	Q9NX45	SOLH2_HUMAN	spermatogenesis and oogenesis specific basic	178					cell differentiation|multicellular organismal development|oogenesis|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	nucleus	DNA binding				0		Breast(139;0.0615)|Lung SC(185;0.0743)|Prostate(109;0.184)	KIRC - Kidney renal clear cell carcinoma(5;0.119)|Kidney(79;0.169)	all cancers(112;4.63e-08)|Epithelial(112;2.67e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.00272)|BRCA - Breast invasive adenocarcinoma(63;0.00685)|GBM - Glioblastoma multiforme(144;0.0273)		TAAAGATTCAGAGCTAGAAAC	0.353000												
FAM48A	55578	broad.mit.edu	37	13	37598543	37598543	+	Missense_Mutation	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr13:37598543C>G	uc001uwg.2	-	18	1614	c.1366G>C	c.(1366-1368)GGG>CGG	p.G456R	FAM48A_uc010abt.2_Missense_Mutation_p.G457R|FAM48A_uc001uwh.2_Missense_Mutation_p.G457R|FAM48A_uc001uwi.2_Missense_Mutation_p.G456R|FAM48A_uc001uwj.2_Missense_Mutation_p.G457R|FAM48A_uc001uwk.2_Missense_Mutation_p.G456R|FAM48A_uc010tes.1_Missense_Mutation_p.G420R|FAM48A_uc001uwl.1_Missense_Mutation_p.G456R|FAM48A_uc001uwd.2_5'Flank|FAM48A_uc001uwe.2_5'UTR|FAM48A_uc001uwf.2_Missense_Mutation_p.G34R	NM_001014286	NP_001014308	Q8NEM7	FA48A_HUMAN	family with sequence similarity 48, member A	456					autophagy|gastrulation	SAGA-type complex	protein binding				0		Lung NSC(96;2.09e-06)|Breast(139;0.014)|Lung SC(185;0.0548)|Prostate(109;0.0959)		all cancers(112;6.06e-07)|Epithelial(112;1.87e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00794)|BRCA - Breast invasive adenocarcinoma(63;0.0128)|GBM - Glioblastoma multiforme(144;0.0477)		ACACCCTTCCCCAATACCGAA	0.378000												
CPB2	1361	broad.mit.edu	37	13	46656606	46656606	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr13:46656606C>T	uc001vaw.2	-	4	421	c.354G>A	c.(352-354)TCG>TCA	p.S118S	uc001vau.1_Intron|uc001vav.1_Intron|CPB2_uc001vax.2_Silent_p.S118S	NM_001872	NP_001863	Q96IY4	CBPB2_HUMAN	plasma carboxypeptidase B2 isoform a	118					blood coagulation|fibrinolysis|proteolysis	extracellular space	metallocarboxypeptidase activity|zinc ion binding			ovary(1)|skin(1)	2		Lung NSC(96;4.21e-05)|Breast(56;0.000118)|Prostate(109;0.00217)|Hepatocellular(98;0.0207)|Lung SC(185;0.0262)|all_neural(104;0.235)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;5.44e-05)		GTTCATAGTACGATGCGGAGG	0.438000												
TTLL5	23093	broad.mit.edu	37	14	76368562	76368562	+	Missense_Mutation	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr14:76368562C>G	uc001xrx.2	+	31	4023	c.3818C>G	c.(3817-3819)TCT>TGT	p.S1273C	TTLL5_uc001xsa.2_Missense_Mutation_p.S347C	NM_015072	NP_055887	Q6EMB2	TTLL5_HUMAN	tubulin tyrosine ligase-like family, member 5	1273					protein modification process|transcription, DNA-dependent	centrosome|cilium|microtubule basal body|nucleus	tubulin-tyrosine ligase activity			ovary(2)|central_nervous_system(1)	3				BRCA - Breast invasive adenocarcinoma(234;0.029)		ATCACCAGCTCTACAGGTTAG	0.557000												
SNW1	22938	broad.mit.edu	37	14	78217691	78217691	+	Missense_Mutation	SNP	T	T	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr14:78217691T>C	uc001xuf.2	-	3	328	c.301A>G	c.(301-303)ATT>GTT	p.I101V	SNW1_uc010tvm.1_Missense_Mutation_p.I26V|SNW1_uc010asu.2_Intron|SNW1_uc010tvn.1_Missense_Mutation_p.I101V	NM_012245	NP_036377	Q13573	SNW1_HUMAN	SKI-interacting protein	101					negative regulation of transcription, DNA-dependent|nuclear mRNA splicing, via spliceosome|regulation of transcription from RNA polymerase II promoter	catalytic step 2 spliceosome|nucleoplasm	Notch binding			ovary(1)	1			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0291)		TGTCGAGCAATTGCATCATAT	0.378000												
C14orf177	283598	broad.mit.edu	37	14	99182681	99182681	+	Silent	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr14:99182681A>G	uc001yfz.1	+	3	572	c.153A>G	c.(151-153)AGA>AGG	p.R51R		NM_182560	NP_872366	Q52M58	CN177_HUMAN	hypothetical protein LOC283598	51											0		Melanoma(154;0.128)				AGAGCCTAAGACATAACAAGC	0.488000												
OTUD7A	161725	broad.mit.edu	37	15	31776753	31776753	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr15:31776753G>A	uc001zfq.2	-	11	1618	c.1525C>T	c.(1525-1527)CGC>TGC	p.R509C	OTUD7A_uc001zfr.2_Missense_Mutation_p.R516C	NM_130901	NP_570971	Q8TE49	OTU7A_HUMAN	OTU domain containing 7A	509	Nuclear localization signal (Potential).					cytoplasm|nucleus	cysteine-type peptidase activity|DNA binding|zinc ion binding			pancreas(1)|skin(1)	2		all_lung(180;1.6e-09)		all cancers(64;2.44e-19)|Epithelial(43;6.82e-14)|GBM - Glioblastoma multiforme(186;1.49e-05)|BRCA - Breast invasive adenocarcinoma(123;0.00189)|Lung(196;0.208)		GAGTCGGCGCGCGTcttgtcc	0.483000												
VPS18	57617	broad.mit.edu	37	15	41192978	41192978	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr15:41192978C>T	uc001zne.2	+	4	2301	c.1962C>T	c.(1960-1962)AAC>AAT	p.N654N		NM_020857	NP_065908	Q9P253	VPS18_HUMAN	vacuolar protein sorting 18	654	Clathrin.				endosome organization|lysosome organization|protein transport	HOPS complex|late endosome membrane|lysosomal membrane	metal ion binding|protein binding			ovary(2)|large_intestine(1)	3		all_cancers(109;1.35e-17)|all_epithelial(112;3.78e-15)|Lung NSC(122;9.68e-11)|all_lung(180;2.25e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;1.07e-05)|COAD - Colon adenocarcinoma(120;0.15)|BRCA - Breast invasive adenocarcinoma(123;0.164)		TCTGCGTGAACGTGCTGGGGG	0.617000												
ASB7	140460	broad.mit.edu	37	15	101170193	101170193	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr15:101170193A>G	uc002bwk.2	+	5	1532	c.763A>G	c.(763-765)ATA>GTA	p.I255V	ASB7_uc002bwj.2_Missense_Mutation_p.I255V	NM_198243	NP_937886	Q9H672	ASB7_HUMAN	ankyrin repeat and SOCS box-containing protein 7	255					intracellular signal transduction					skin(1)	1	Lung NSC(78;0.00121)|all_lung(78;0.00152)|Melanoma(26;0.00852)		OV - Ovarian serous cystadenocarcinoma(32;0.00168)|LUSC - Lung squamous cell carcinoma(107;0.0766)|Lung(145;0.103)			GGCTGTTTCAATAAGTATTTC	0.368000												
KIAA0430	9665	broad.mit.edu	37	16	15732982	15732982	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr16:15732982G>A	uc002ddr.2	-	2	302	c.109C>T	c.(109-111)CGT>TGT	p.R37C	KIAA0430_uc002ddq.2_Missense_Mutation_p.R36C|KIAA0430_uc010uzv.1_Missense_Mutation_p.R36C|KIAA0430_uc010uzw.1_Missense_Mutation_p.R36C|KIAA0430_uc010uzx.1_Missense_Mutation_p.R36C	NM_014647	NP_055462	Q9Y4F3	LKAP_HUMAN	limkain b1	36						peroxisome	nucleotide binding|RNA binding				0						TGCTCAGGACGAGAAAAGCAA	0.443000												
RABEP2	79874	broad.mit.edu	37	16	28926046	28926046	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr16:28926046C>T	uc002drq.2	-	4	538	c.490G>A	c.(490-492)GAG>AAG	p.E164K	uc010vct.1_Intron|RABEP2_uc010vdf.1_Missense_Mutation_p.E93K|RABEP2_uc010byn.2_Missense_Mutation_p.E164K|RABEP2_uc002drr.2_Missense_Mutation_p.E164K	NM_024816	NP_079092	Q9H5N1	RABE2_HUMAN	rabaptin, RAB GTPase binding effector protein 2	164	Potential.				endocytosis|protein transport	early endosome	growth factor activity|GTPase activator activity			ovary(1)|breast(1)|skin(1)	3						TTCAGCTCCTCGATCTCCTTT	0.642000												
OSGIN1	29948	broad.mit.edu	37	16	83998836	83998836	+	Missense_Mutation	SNP	T	T	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr16:83998836T>G	uc002fha.2	+	7	1290	c.907T>G	c.(907-909)TTC>GTC	p.F303V	OSGIN1_uc002fhb.2_Missense_Mutation_p.F220V|OSGIN1_uc002fhc.2_Missense_Mutation_p.F220V	NM_013370	NP_037502	Q9UJX0	OSGI1_HUMAN	oxidative stress induced growth inhibitor 1	303					cell differentiation|multicellular organismal development|negative regulation of cell growth		growth factor activity				0						CAGCCCCCTCTTCCAGGTGAG	0.677000												
FOXF1	2294	broad.mit.edu	37	16	86544645	86544645	+	Missense_Mutation	SNP	T	T	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr16:86544645T>C	uc002fjl.2	+	1	513	c.470T>C	c.(469-471)ATG>ACG	p.M157T	uc002fjk.1_5'Flank	NM_001451	NP_001442	Q12946	FOXF1_HUMAN	forkhead box F1	157					branching involved in open tracheal system development|cardiac left ventricle morphogenesis|embryonic ectodermal digestive tract morphogenesis|endocardial cushion development|in utero embryonic development|lung vasculature development|midgut development|pancreas development|positive regulation of transcription, DNA-dependent|regulation of sequence-specific DNA binding transcription factor activity|ureter development|venous blood vessel development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription factor binding				0						ATGTACAGCATGATGAACGGG	0.682000												
TP53	7157	broad.mit.edu	37	17	7578190	7578190	+	Missense_Mutation	SNP	T	T	C	rs121912666		TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr17:7578190T>C	uc002gim.2	-	6	853	c.659A>G	c.(658-660)TAT>TGT	p.Y220C	TP53_uc002gig.1_Missense_Mutation_p.Y220C|TP53_uc002gih.2_Missense_Mutation_p.Y220C|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_Missense_Mutation_p.Y88C|TP53_uc010cng.1_Missense_Mutation_p.Y88C|TP53_uc002gii.1_Missense_Mutation_p.Y88C|TP53_uc010cnh.1_Missense_Mutation_p.Y220C|TP53_uc010cni.1_Missense_Mutation_p.Y220C|TP53_uc002gij.2_Missense_Mutation_p.Y220C|TP53_uc010cnj.1_Intron|TP53_uc002gin.2_Missense_Mutation_p.Y127C|TP53_uc002gio.2_Missense_Mutation_p.Y88C|TP53_uc010vug.1_Missense_Mutation_p.Y181C	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	220	Required for interaction with FBXO42.||Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).		Y -> N (in sporadic cancers; somatic mutation).|Y -> H (in sporadic cancers; somatic mutation).|Y -> S (in a brain tumor with no family history; germline mutation and in sporadic cancers; somatic mutation).|Y -> F (in a sporadic cancer; somatic mutation).|Y -> D (in sporadic cancers; somatic mutation).|Y -> C (in LFS; germline mutation and in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.Y220C(205)|p.Y220N(12)|p.Y220H(9)|p.Y220S(9)|p.0?(7)|p.Y220fs*27(4)|p.Y220*(3)|p.Y220D(2)|p.Y127C(2)|p.D208fs*1(1)|p.Y220_P223delYEPP(1)|p.?(1)|p.V218_E224delVPYEPPE(1)|p.V218_E221delVPYE(1)|p.V218_Y220delVPY(1)|p.Y220fs*25(1)|p.V216_Y220delVVVPY(1)|p.Y220fs*1(1)|p.Y220fs*2(1)|p.V218fs*26(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		AGGCGGCTCATAGGGCACCAC	0.557000		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)		
KRT28	162605	broad.mit.edu	37	17	38954574	38954574	+	Silent	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr17:38954574G>A	uc002hvh.1	-	3	669	c.603C>T	c.(601-603)GAC>GAT	p.D201D		NM_181535	NP_853513	Q7Z3Y7	K1C28_HUMAN	keratin 25D	201	Rod.|Coil 1B.					cytoplasm|intermediate filament	structural molecule activity			ovary(1)	1		Breast(137;0.000301)				GCGTCAGCTCGTCCAGGACTC	0.502000												
TTC25	83538	broad.mit.edu	37	17	40094927	40094927	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr17:40094927G>C	uc002hyj.3	+	6	832	c.743G>C	c.(742-744)AGG>ACG	p.R248T	TTC25_uc010cxt.2_RNA|TTC25_uc010cxs.1_Intron	NM_031421	NP_113609	Q96NG3	TTC25_HUMAN	tetratricopeptide repeat domain 25	248						cytoplasm	protein binding			ovary(1)	1		all_cancers(22;8.16e-06)|Breast(137;0.000143)|all_epithelial(22;0.000236)				ATCTACGCCAGGGAGCGGGAC	0.572000												
CNDP2	55748	broad.mit.edu	37	18	72173101	72173101	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr18:72173101G>C	uc002llm.1	+	4	384	c.222G>C	c.(220-222)GAG>GAC	p.E74D	CNDP2_uc002lln.1_Intron|CNDP2_uc002llo.2_Missense_Mutation_p.E74D|CNDP2_uc002llp.1_5'Flank	NM_018235	NP_060705	Q96KP4	CNDP2_HUMAN	CNDP dipeptidase 2	74						cytoplasm	carboxypeptidase activity|metal ion binding|metallopeptidase activity|protein binding|tripeptidase activity			ovary(2)|skin(1)	3		Esophageal squamous(42;0.131)|Prostate(75;0.173)		BRCA - Breast invasive adenocarcinoma(31;0.22)		ATGGCTCGGAGATCCCGCTCC	0.542000												
LONP1	9361	broad.mit.edu	37	19	5694792	5694792	+	Silent	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:5694792G>A	uc002mcx.2	-	14	2167	c.2134C>T	c.(2134-2136)CTG>TTG	p.L712L	LONP1_uc002mcy.2_Silent_p.L648L|LONP1_uc010duh.2_Silent_p.L453L|LONP1_uc010dui.2_Silent_p.L696L|LONP1_uc002mcz.2_Silent_p.L516L	NM_004793	NP_004784	P36776	LONM_HUMAN	mitochondrial lon peptidase 1 precursor	712					cellular chaperone-mediated protein complex assembly|cellular response to oxidative stress|misfolded or incompletely synthesized protein catabolic process|mitochondrial DNA metabolic process|oxidation-dependent protein catabolic process|protein homooligomerization|response to hypoxia	mitochondrial nucleoid	ADP binding|ATP binding|ATP-dependent peptidase activity|DNA polymerase binding|G-quadruplex DNA binding|mitochondrial heavy strand promoter anti-sense binding|mitochondrial light strand promoter anti-sense binding|sequence-specific DNA binding|serine-type endopeptidase activity|single-stranded DNA binding|single-stranded RNA binding				0						TGCTTCTGCAGGTTGCGGACA	0.637000												
CRTC1	23373	broad.mit.edu	37	19	18871039	18871039	+	Splice_Site	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:18871039G>A	uc002nkb.3	+	8	974	c.886_splice	c.e8+1	p.G296_splice	CRTC1_uc010ebv.2_Splice_Site_p.G312_splice|CRTC1_uc010ebw.2_Splice_Site_p.G161_splice|CRTC1_uc002nkc.3_Splice_Site_p.G161_splice	NM_015321	NP_056136	Q6UUV9	CRTC1_HUMAN	mucoepidermoid carcinoma translocated 1 isoform						interspecies interaction between organisms|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|nucleus|plasma membrane	cAMP response element binding protein binding|protein binding		CRTC1/MAML2(516)	salivary_gland(474)|lung(35)|thyroid(4)|breast(3)|skin(2)|ovary(1)	519						GCCGGCCAGGGTAAGGCAGGG	0.652000												
NDUFA13	51079	broad.mit.edu	37	19	19645850	19645850	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:19645850C>T	uc010xqy.1	+	5	831	c.572C>T	c.(571-573)CCG>CTG	p.P191L	NDUFA13_uc010xqx.1_3'UTR|YJEFN3_uc002nmt.1_Missense_Mutation_p.P109L|YJEFN3_uc010ecf.1_Missense_Mutation_p.P59L|YJEFN3_uc002nmu.1_RNA	NM_015965	NP_057049	Q9P0J0	NDUAD_HUMAN	NADH dehydrogenase (ubiquinone) 1 alpha	Error:Variant_position_missing_in_Q9P0J0_after_alignment					apoptotic nuclear change|induction of apoptosis by extracellular signals|negative regulation of cell growth|negative regulation of transcription, DNA-dependent|negative regulation of translation|protein import into nucleus|reactive oxygen species metabolic process|respiratory electron transport chain	integral to membrane|mitochondrial respiratory chain complex I|nucleoplasm	ATP binding|NADH dehydrogenase (ubiquinone) activity|protein binding				0					NADH(DB00157)	CAGGCGTTCCCGTTGCCCGCT	0.498000												
ZNF226	7769	broad.mit.edu	37	19	44680182	44680182	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:44680182A>G	uc002oyp.2	+	6	911	c.767A>G	c.(766-768)GAG>GGG	p.E256G	ZNF226_uc002oyq.2_Missense_Mutation_p.E139G|ZNF226_uc002oyr.2_Missense_Mutation_p.E139G|ZNF226_uc010ejg.2_3'UTR|ZNF226_uc002oys.2_Missense_Mutation_p.E256G|ZNF226_uc002oyt.2_Missense_Mutation_p.E256G	NM_001032373	NP_001027545	Q9NYT6	ZN226_HUMAN	zinc finger protein 226 isoform a	256	C2H2-type 1; degenerate.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0		Prostate(69;0.0352)|all_neural(266;0.202)				CAGTGTAATGAGTGTAAAAAA	0.383000												
TPRX1	284355	broad.mit.edu	37	19	48305321	48305321	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:48305321G>A	uc002php.1	-	2	1018	c.947C>T	c.(946-948)TCA>TTA	p.S316L		NM_198479	NP_940881	Q8N7U7	TPRX1_HUMAN	tetra-peptide repeat homeobox	316	Gly-rich.					nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0		all_cancers(25;3.02e-09)|all_epithelial(76;7e-07)|all_lung(116;2.48e-06)|Lung NSC(112;5.15e-06)|Ovarian(192;0.0139)|all_neural(266;0.0146)|Breast(70;0.133)		OV - Ovarian serous cystadenocarcinoma(262;0.000241)|all cancers(93;0.00036)|Epithelial(262;0.0127)|GBM - Glioblastoma multiforme(486;0.048)		agctgggactgagcctgagcc	0.368000												
LILRA3	11026	broad.mit.edu	37	19	54802685	54802685	+	Silent	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr19:54802685G>A	uc002qfd.2	-	5	821	c.756C>T	c.(754-756)TAC>TAT	p.Y252Y	LILRA6_uc002qew.1_Intron|LILRA3_uc010erk.2_Silent_p.Y188Y	NM_006865	NP_006856	Q8N6C8	LIRA3_HUMAN	leukocyte immunoglobulin-like receptor,	252	Ig-like C2-type 3.				defense response	extracellular region|plasma membrane	antigen binding|receptor activity			ovary(1)	1	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.105)		CAAATCTGTCGTAGCCGGCAT	0.627000												
PXDN	7837	broad.mit.edu	37	2	1677555	1677555	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:1677555C>T	uc002qxa.2	-	9	942	c.878G>A	c.(877-879)CGC>CAC	p.R293H	PXDN_uc002qxb.1_Missense_Mutation_p.R293H|PXDN_uc002qxc.1_Missense_Mutation_p.R110H	NM_012293	NP_036425	Q92626	PXDN_HUMAN	peroxidasin precursor	293	Ig-like C2-type 1.				extracellular matrix organization|hydrogen peroxide catabolic process|immune response	endoplasmic reticulum|extracellular space|proteinaceous extracellular matrix	extracellular matrix structural constituent|heme binding|interleukin-1 receptor antagonist activity|peroxidase activity			pancreas(6)|ovary(2)	8	Acute lymphoblastic leukemia(172;0.0627)|all_hematologic(175;0.0797)	all_cancers(51;0.0845)|Lung NSC(108;0.00641)|all_epithelial(98;0.00716)		all cancers(51;0.0492)|OV - Ovarian serous cystadenocarcinoma(76;0.0973)|Epithelial(75;0.17)|GBM - Glioblastoma multiforme(21;0.228)		CAAGTTTAGGCGGGAATCTGT	0.507000												
WDR35	57539	broad.mit.edu	37	2	20113327	20113327	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:20113327C>T	uc002rdi.2	-	28	3646	c.3538G>A	c.(3538-3540)GTG>ATG	p.V1180M	WDR35_uc002rdj.2_Missense_Mutation_p.V1169M|WDR35_uc010ext.2_RNA|WDR35_uc002rdh.2_3'UTR	NM_001006657	NP_001006658	Q9P2L0	WDR35_HUMAN	WD repeat domain 35 isoform 1	1180										ovary(1)	1	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					CTTTATCCCACTGGACTATGG	0.368000												
BAZ2B	29994	broad.mit.edu	37	2	160303427	160303427	+	Missense_Mutation	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:160303427C>G	uc002uao.2	-	6	914	c.562G>C	c.(562-564)GTA>CTA	p.V188L	BAZ2B_uc002uap.2_Missense_Mutation_p.V186L|BAZ2B_uc002uas.1_Missense_Mutation_p.V125L|BAZ2B_uc002uau.1_Missense_Mutation_p.V186L|BAZ2B_uc002uaq.1_Missense_Mutation_p.V116L|BAZ2B_uc002uat.3_Missense_Mutation_p.V125L|BAZ2B_uc010fop.1_Missense_Mutation_p.V186L	NM_013450	NP_038478	Q9UIF8	BAZ2B_HUMAN	bromodomain adjacent to zinc finger domain, 2B	188	Ser-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|protein binding|zinc ion binding			ovary(3)|skin(1)	4						GTGGATAGTACAGATGTGTTG	0.318000												
XIRP2	129446	broad.mit.edu	37	2	168105100	168105100	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:168105100G>C	uc002udx.2	+	8	7216	c.7198G>C	c.(7198-7200)GAA>CAA	p.E2400Q	XIRP2_uc010fpn.2_Intron|XIRP2_uc010fpo.2_Intron|XIRP2_uc010fpp.2_Intron|XIRP2_uc002udy.2_Missense_Mutation_p.E2225Q|XIRP2_uc010fpq.2_Missense_Mutation_p.E2178Q|XIRP2_uc010fpr.2_Intron|XIRP2_uc010fps.1_Intron	NM_152381	NP_689594	A4UGR9	XIRP2_HUMAN	xin actin-binding repeat containing 2 isoform 1	2225					actin cytoskeleton organization	cell junction	actin binding			skin(7)|ovary(6)|pancreas(1)	14						TTCCCAAAAAGAAGCCTCGAA	0.473000												
TTN	7273	broad.mit.edu	37	2	179407078	179407078	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:179407078C>T	uc010zfg.1	-	298	89925	c.89701G>A	c.(89701-89703)GAG>AAG	p.E29901K	uc002umo.2_RNA|uc002ump.1_Intron|TTN_uc010zfh.1_Missense_Mutation_p.E23596K|TTN_uc010zfi.1_Missense_Mutation_p.E23529K|TTN_uc010zfj.1_Missense_Mutation_p.E23404K	NM_133378	NP_596869	Q8WZ42	TITIN_HUMAN	titin isoform N2-A	30828							ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			ovary(58)|stomach(19)|large_intestine(17)|lung(16)|skin(16)|breast(10)|pancreas(7)|kidney(4)|central_nervous_system(3)|urinary_tract(2)|upper_aerodigestive_tract(1)	153			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			AACACATACTCATTTCCTTCG	0.512000												
DGKD	8527	broad.mit.edu	37	2	234356752	234356752	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:234356752A>G	uc002vui.1	+	13	1451	c.1439A>G	c.(1438-1440)TAT>TGT	p.Y480C	DGKD_uc002vuj.1_Missense_Mutation_p.Y436C|DGKD_uc010fyh.1_Missense_Mutation_p.Y347C|DGKD_uc010fyi.1_RNA	NM_152879	NP_690618	Q16760	DGKD_HUMAN	diacylglycerol kinase, delta 130kDa isoform 2	480					activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|cell growth|diacylglycerol metabolic process|endocytosis|epidermal growth factor receptor signaling pathway|multicellular organismal development|platelet activation|protein homooligomerization|protein transport|response to organic substance|second-messenger-mediated signaling	cytoplasm|cytoplasmic membrane-bounded vesicle|plasma membrane|plasma membrane	ATP binding|diacylglycerol binding|diacylglycerol kinase activity|metal ion binding|protein heterodimerization activity|protein homodimerization activity			central_nervous_system(2)|pancreas(1)|lung(1)|skin(1)	5		Breast(86;0.0013)|Renal(207;0.00339)|all_hematologic(139;0.0116)|all_lung(227;0.0179)|Acute lymphoblastic leukemia(138;0.0326)|Lung NSC(271;0.0538)		Epithelial(121;1.31e-16)|BRCA - Breast invasive adenocarcinoma(100;0.000416)|Lung(119;0.00285)|LUSC - Lung squamous cell carcinoma(224;0.00655)	Phosphatidylserine(DB00144)	ATTCTCTTCTATGAAGACTCG	0.562000												
YDJC	150223	broad.mit.edu	37	22	21984216	21984216	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr22:21984216G>C	uc002zvb.2	-	1	125	c.88C>G	c.(88-90)CTG>GTG	p.L30V	YDJC_uc002zvc.2_RNA|YDJC_uc002zvd.2_Missense_Mutation_p.L30V|CCDC116_uc011aih.1_5'Flank|CCDC116_uc002zve.2_5'Flank	NM_001017964	NP_001017964	A8MPS7	YDJC_HUMAN	YdjC homolog	30					carbohydrate metabolic process		hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds				0	Colorectal(54;0.105)					GCCCCGGCCAGAAAGGCCTCC	0.706000												
MKL1	57591	broad.mit.edu	37	22	40859227	40859227	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr22:40859227G>C	uc003ayv.1	-	1	212	c.5C>G	c.(4-6)CCG>CGG	p.P2R	MKL1_uc003ayw.1_Missense_Mutation_p.P2R|MKL1_uc010gye.1_Missense_Mutation_p.P2R|MKL1_uc010gyf.1_Missense_Mutation_p.P2R|MKL1_uc003ayy.1_RNA	NM_020831	NP_065882	Q969V6	MKL1_HUMAN	megakaryoblastic leukemia 1 protein	2	Mediates interaction with SCAI and ACTB (By similarity).				positive regulation of transcription from RNA polymerase II promoter|smooth muscle cell differentiation|transcription, DNA-dependent	cytoplasm|nucleus	actin monomer binding|leucine zipper domain binding|nucleic acid binding|transcription coactivator activity			ovary(2)|lung(1)|breast(1)|central_nervous_system(1)	5						GCACTTACGCGGCATGATCCC	0.527000			T	RBM15	acute megakaryocytic leukemia							
CCDC71	64925	broad.mit.edu	37	3	49200783	49200783	+	Nonsense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr3:49200783G>A	uc003cwg.3	-	2	997	c.859C>T	c.(859-861)CGA>TGA	p.R287*		NM_022903	NP_075054	Q8IV32	CCD71_HUMAN	coiled-coil domain containing 71	287	Potential.									ovary(1)	1				BRCA - Breast invasive adenocarcinoma(193;8.01e-05)|Kidney(197;0.00217)|KIRC - Kidney renal clear cell carcinoma(197;0.00244)		GCCAGTGTTCGAGCTACCTTG	0.547000												
TMEM45A	55076	broad.mit.edu	37	3	100275725	100275725	+	Silent	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr3:100275725G>C	uc003dtz.1	+	3	625	c.312G>C	c.(310-312)CTG>CTC	p.L104L	TMEM45A_uc003dua.1_Silent_p.L120L	NM_018004	NP_060474	Q9NWC5	TM45A_HUMAN	transmembrane protein 45A	104	Helical; (Potential).					integral to membrane				skin(2)|ovary(1)	3						TCTTTGGGCTGTTGGGTGTGG	0.428000												
ALG1L	200810	broad.mit.edu	37	3	125648331	125648331	+	Missense_Mutation	SNP	C	C	T	rs145742427	byFrequency	TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr3:125648331C>T	uc003eig.1	-	6	592	c.428G>A	c.(427-429)CGA>CAA	p.R143Q	LOC100125556_uc003eif.3_RNA|LOC100125556_uc003eid.3_RNA|LOC100125556_uc003eie.3_RNA	NM_001015050	NP_001015050	Q6GMV1	ALG1L_HUMAN	asparagine-linked glycosylation 1-like	143							transferase activity, transferring glycosyl groups				0						CTCATCCCATCGGAGCTGCTG	0.532000												
PIK3CB	5291	broad.mit.edu	37	3	138426123	138426123	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr3:138426123C>T	uc011bmq.1	-	9	1408	c.1408G>A	c.(1408-1410)GAA>AAA	p.E470K	PIK3CB_uc011bmn.1_5'UTR|PIK3CB_uc011bmo.1_Intron|PIK3CB_uc011bmp.1_Missense_Mutation_p.E74K	NM_006219	NP_006210	P42338	PK3CB_HUMAN	catalytic phosphatidylinositol 3-kinase beta	470	C2 PI3K-type.				activation of MAPK activity|chemotaxis|fibroblast growth factor receptor signaling pathway|G-protein coupled receptor protein signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|platelet activation|T cell receptor signaling pathway	phosphatidylinositol 3-kinase complex	1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity			breast(2)|ovary(1)|lung(1)|skin(1)	5						AACATTTCTTCGAGTTCATCT	0.313000												
PACRGL	133015	broad.mit.edu	37	4	20714515	20714515	+	Silent	SNP	T	T	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr4:20714515T>A	uc010iek.2	+	6	862	c.471T>A	c.(469-471)CCT>CCA	p.P157P	PACRGL_uc003gpu.2_RNA|PACRGL_uc010iei.1_Silent_p.P205P|PACRGL_uc003gpz.2_Silent_p.P157P|PACRGL_uc011bxm.1_Silent_p.P104P|PACRGL_uc003gqa.2_Intron|PACRGL_uc003gpx.3_RNA|PACRGL_uc003gpv.2_Silent_p.P157P|PACRGL_uc003gpw.2_RNA|PACRGL_uc010iej.1_RNA|PACRGL_uc011bxn.1_Intron|PACRGL_uc003gpy.2_Silent_p.P104P	NM_145048	NP_659485	Q8N7B6	PACRL_HUMAN	PARK2 co-regulated-like isoform 1	157							binding				0						CTTTGCTACCTAGACTGATTC	0.348000												
HEATR7B2	133558	broad.mit.edu	37	5	41000403	41000403	+	Missense_Mutation	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:41000403C>G	uc003jmj.3	-	39	4891	c.4401G>C	c.(4399-4401)GAG>GAC	p.E1467D	HEATR7B2_uc003jmi.3_Missense_Mutation_p.E1022D	NM_173489	NP_775760	Q7Z745	HTRB2_HUMAN	HEAT repeat family member 7B2	1467							binding			ovary(6)|central_nervous_system(2)	8						CCCCATAGAGCTCCTGGAGGC	0.488000												
HCN1	348980	broad.mit.edu	37	5	45303801	45303801	+	Silent	SNP	T	T	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:45303801T>C	uc003jok.2	-	6	1543	c.1518A>G	c.(1516-1518)GGA>GGG	p.G506G		NM_021072	NP_066550	O60741	HCN1_HUMAN	hyperpolarization activated cyclic	506	cAMP.|Cytoplasmic (Potential).					integral to membrane	cAMP binding|sodium channel activity|voltage-gated potassium channel activity			ovary(1)	1						TACCCACGGCTCCTTCTCGTA	0.403000												
BRD8	10902	broad.mit.edu	37	5	137488173	137488173	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:137488173C>T	uc003lcf.1	-	21	2909	c.2854G>A	c.(2854-2856)GAG>AAG	p.E952K	BRD8_uc003lcc.1_Intron	NM_139199	NP_631938	Q9H0E9	BRD8_HUMAN	bromodomain containing 8 isoform 2	952					cell surface receptor linked signaling pathway|histone H2A acetylation|histone H4 acetylation|regulation of growth|regulation of transcription from RNA polymerase II promoter	mitochondrion|NuA4 histone acetyltransferase complex	sequence-specific DNA binding transcription factor activity|thyroid hormone receptor activity			ovary(1)	1			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0109)			ACTGTTACCTCAGAGAGAAAG	0.448000												
PCDHAC1	56135	broad.mit.edu	37	5	140308819	140308819	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:140308819G>A	uc003lih.2	+	1	2518	c.2342G>A	c.(2341-2343)CGA>CAA	p.R781Q	PCDHA1_uc003lha.2_Intron|PCDHA1_uc003lhb.2_Intron|PCDHA2_uc003lhd.2_Intron|PCDHA3_uc003lhf.2_Intron|PCDHA4_uc003lhi.2_Intron|PCDHA4_uc003lhh.1_Intron|PCDHA5_uc003lhk.1_Intron|PCDHA5_uc003lhl.2_Intron|PCDHA6_uc003lhn.2_Intron|PCDHA6_uc003lho.2_Intron|PCDHA7_uc003lhq.2_Intron|PCDHA8_uc003lhs.2_Intron|PCDHA9_uc003lhu.2_Intron|PCDHA10_uc003lhw.2_Intron|PCDHA10_uc003lhx.2_Intron|PCDHA11_uc003lia.2_Intron|PCDHA12_uc003lic.2_Intron|PCDHA13_uc003lie.1_Intron|PCDHA13_uc003lif.2_Intron|PCDHAC1_uc003lig.1_Missense_Mutation_p.R781Q	NM_018898	NP_061721	Q9H158	PCDC1_HUMAN	protocadherin alpha subfamily C, 1 isoform 1	781	Cytoplasmic (Potential).				homophilic cell adhesion|nervous system development	integral to plasma membrane	calcium ion binding			skin(3)|ovary(2)	5			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GCCGACCTGCGAAATCTTGCC	0.468000												
PCDHB11	56125	broad.mit.edu	37	5	140580416	140580416	+	Missense_Mutation	SNP	C	C	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:140580416C>A	uc003liy.2	+	1	1069	c.1069C>A	c.(1069-1071)CCA>ACA	p.P357T	PCDHB11_uc011daj.1_5'UTR	NM_018931	NP_061754	Q9Y5F2	PCDBB_HUMAN	protocadherin beta 11 precursor	357	Extracellular (Potential).|Cadherin 4.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			skin(3)|ovary(2)|upper_aerodigestive_tract(1)	6			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			CAGTCCAATCCCAGAAAATAC	0.423000												
PCDHGA11	56105	broad.mit.edu	37	5	140803086	140803086	+	Silent	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:140803086G>A	uc003lkq.1	+	1	2550	c.2292G>A	c.(2290-2292)TCG>TCA	p.S764S	PCDHGA1_uc003lji.1_Intron|PCDHGA2_uc003ljk.1_Intron|PCDHGA3_uc003ljm.1_Intron|PCDHGA3_uc010jfx.1_Intron|PCDHGB1_uc003ljo.1_Intron|PCDHGA4_uc003ljq.1_Intron|PCDHGB2_uc003ljs.1_Intron|PCDHGA5_uc003lju.1_Intron|PCDHGB3_uc003ljw.1_Intron|PCDHGA6_uc003ljy.1_Intron|PCDHGA7_uc003lka.1_Intron|PCDHGB4_uc003lkc.1_Intron|PCDHGA8_uc003lkd.1_Intron|PCDHGB5_uc003lkf.1_Intron|PCDHGA9_uc003lkh.1_Intron|PCDHGB6_uc003lkj.1_Intron|PCDHGA10_uc003lkl.1_Intron|PCDHGB7_uc003lkn.1_Intron|PCDHGA11_uc003lko.1_Silent_p.S764S|PCDHGA11_uc003lkp.1_Intron|PCDHGB8P_uc011daz.1_5'Flank	NM_018914	NP_061737	Q9Y5H2	PCDGB_HUMAN	protocadherin gamma subfamily A, 11 isoform 1	764	Cytoplasmic (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding				0			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			TTGCGGACTCGCAGAAGAGTC	0.552000												
HAVCR2	84868	broad.mit.edu	37	5	156514152	156514152	+	Silent	SNP	T	T	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:156514152T>C	uc003lwk.1	-	7	1011	c.867A>G	c.(865-867)CAA>CAG	p.Q289Q		NM_032782	NP_116171	Q8TDQ0	HAVR2_HUMAN	T cell immunoglobulin mucin 3 precursor	289	Cytoplasmic (Potential).					integral to membrane					0	Renal(175;0.00212)	Medulloblastoma(196;0.0354)|all_neural(177;0.0999)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			GTTGTGAGGGTTGCTGCCTGC	0.428000												
BTN3A3	10384	broad.mit.edu	37	6	26452383	26452383	+	Missense_Mutation	SNP	G	G	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:26452383G>T	uc003nhz.2	+	11	1679	c.1499G>T	c.(1498-1500)AGA>ATA	p.R500I	BTN3A3_uc003nia.2_Missense_Mutation_p.R458I|BTN3A3_uc011dkn.1_Missense_Mutation_p.R451I	NM_006994	NP_008925	O00478	BT3A3_HUMAN	butyrophilin, subfamily 3, member A3 isoform a	500	B30.2/SPRY.|Cytoplasmic (Potential).					integral to membrane					0						CCTGTTTTCAGAATTTTGACC	0.478000												
KCNQ5	56479	broad.mit.edu	37	6	73900379	73900379	+	Missense_Mutation	SNP	C	C	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:73900379C>G	uc003pgk.2	+	12	2008	c.1661C>G	c.(1660-1662)TCT>TGT	p.S554C	KCNQ5_uc011dyh.1_Missense_Mutation_p.S573C|KCNQ5_uc011dyi.1_Missense_Mutation_p.S564C|KCNQ5_uc010kat.2_Missense_Mutation_p.S545C|KCNQ5_uc011dyj.1_Missense_Mutation_p.S444C|KCNQ5_uc011dyk.1_Missense_Mutation_p.S304C	NM_019842	NP_062816	Q9NR82	KCNQ5_HUMAN	potassium voltage-gated channel, KQT-like	554					protein complex assembly|synaptic transmission	voltage-gated potassium channel complex	inward rectifier potassium channel activity			ovary(4)|large_intestine(2)|skin(1)	7		all_epithelial(107;0.116)|Lung NSC(302;0.219)		COAD - Colon adenocarcinoma(1;0.0107)|Colorectal(1;0.0583)		GAACAATATTCTGCTGGTCAT	0.343000												
COL10A1	1300	broad.mit.edu	37	6	116442804	116442804	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:116442804C>T	uc003pwm.2	-	3	571	c.475G>A	c.(475-477)GGA>AGA	p.G159R	NT5DC1_uc003pwj.2_Intron|NT5DC1_uc003pwk.2_Intron|NT5DC1_uc003pwl.2_Intron	NM_000493	NP_000484	Q03692	COAA1_HUMAN	type X collagen alpha 1 precursor	159	Triple-helical region.				skeletal system development	collagen	metal ion binding			central_nervous_system(1)	1		all_cancers(87;0.0176)|all_epithelial(87;0.0263)|Colorectal(196;0.234)		all cancers(137;0.0157)|OV - Ovarian serous cystadenocarcinoma(136;0.0325)|GBM - Glioblastoma multiforme(226;0.0446)|Epithelial(106;0.0711)		CCCTGTTGTCCAGGTTTTCCT	0.597000												
RNF146	81847	broad.mit.edu	37	6	127608243	127608243	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:127608243G>A	uc003qav.2	+	3	644	c.485G>A	c.(484-486)CGT>CAT	p.R162H	RNF146_uc003qat.2_Missense_Mutation_p.R161H|RNF146_uc003qau.2_Missense_Mutation_p.R161H|RNF146_uc003qaw.2_Missense_Mutation_p.R161H	NM_030963	NP_112225	Q9NTX7	RN146_HUMAN	ring finger protein 146	162	WWE.				positive regulation of canonical Wnt receptor signaling pathway|protein autoubiquitination|protein K48-linked ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|Wnt receptor signaling pathway	cytosol	poly-ADP-D-ribose binding|protein binding|ubiquitin-protein ligase activity|zinc ion binding			kidney(1)	1				GBM - Glioblastoma multiforme(226;0.0407)|all cancers(137;0.2)		GAACATGGACGTCGCAGGAAG	0.388000												
PTPRK	5796	broad.mit.edu	37	6	128388735	128388735	+	Missense_Mutation	SNP	A	A	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:128388735A>C	uc003qbk.2	-	12	2453	c.2086T>G	c.(2086-2088)TTT>GTT	p.F696V	PTPRK_uc003qbj.2_Missense_Mutation_p.F696V|PTPRK_uc010kfc.2_Missense_Mutation_p.F696V|PTPRK_uc011ebu.1_Missense_Mutation_p.F696V|PTPRK_uc003qbl.1_Missense_Mutation_p.F566V|PTPRK_uc011ebv.1_Missense_Mutation_p.F696V	NM_002844	NP_002835	Q15262	PTPRK_HUMAN	protein tyrosine phosphatase, receptor type, K	696	Extracellular (Potential).				cell migration|cellular response to reactive oxygen species|cellular response to UV|focal adhesion assembly|negative regulation of cell cycle|negative regulation of cell migration|negative regulation of keratinocyte proliferation|negative regulation of transcription, DNA-dependent|protein localization at cell surface|transforming growth factor beta receptor signaling pathway	adherens junction|cell surface|cell-cell junction|integral to plasma membrane|leading edge membrane	beta-catenin binding|gamma-catenin binding|protein kinase binding|transmembrane receptor protein tyrosine phosphatase activity			ovary(3)|skin(2)|pancreas(1)|kidney(1)|central_nervous_system(1)	8				all cancers(137;0.0118)|GBM - Glioblastoma multiforme(226;0.0372)|OV - Ovarian serous cystadenocarcinoma(136;0.24)		GGGTTCCAAAAGCCTTGGTAG	0.547000												
SUMO4	387082	broad.mit.edu	37	6	149721793	149721793	+	Missense_Mutation	SNP	A	A	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:149721793A>C	uc003qml.2	+	1	299	c.266A>C	c.(265-267)CAG>CCG	p.Q89P	TAB2_uc011eec.1_Intron|TAB2_uc003qmj.2_Intron|TAB2_uc003qmk.3_Intron	NM_001002255	NP_001002255	Q6EEV6	SUMO4_HUMAN	SMT3 suppressor of mif two 3 homolog 4	89	Ubiquitin-like.										0		Ovarian(120;0.0164)		OV - Ovarian serous cystadenocarcinoma(155;7.91e-12)|GBM - Glioblastoma multiforme(68;0.0282)		GTGTTTCAACAGCCTACGGGA	0.423000												
RSPH3	83861	broad.mit.edu	37	6	159401861	159401861	+	Silent	SNP	C	C	T	rs148058820	by1000genomes	TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr6:159401861C>T	uc003qrx.2	-	6	1420	c.1230G>A	c.(1228-1230)CCG>CCA	p.P410P	RSPH3_uc010kju.2_Silent_p.P314P	NM_031924	NP_114130	Q86UC2	RSPH3_HUMAN	radial spoke 3 homolog	410										ovary(1)|skin(1)	2		Breast(66;0.00519)|Ovarian(120;0.123)		OV - Ovarian serous cystadenocarcinoma(65;2.36e-16)|BRCA - Breast invasive adenocarcinoma(81;5.92e-06)		CAAAAACAGACGGGAGAAGGT	0.423000												
IQUB	154865	broad.mit.edu	37	7	123143002	123143002	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr7:123143002G>A	uc003vkn.2	-	5	1440	c.863C>T	c.(862-864)ACG>ATG	p.T288M	IQUB_uc003vko.2_Missense_Mutation_p.T288M|IQUB_uc010lkt.2_RNA|IQUB_uc003vkp.1_Missense_Mutation_p.T288M|IQUB_uc003vkq.2_3'UTR	NM_178827	NP_849149	Q8NA54	IQUB_HUMAN	IQ motif and ubiquitin domain containing	288										ovary(3)|large_intestine(1)	4						CATTACCTGCGTATCCCTACA	0.343000												
GPR37	2861	broad.mit.edu	37	7	124404795	124404795	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr7:124404795G>A	uc003vli.2	-	1	887	c.236C>T	c.(235-237)GCG>GTG	p.A79V		NM_005302	NP_005293	O15354	GPR37_HUMAN	G protein-coupled receptor 37 precursor	79	Extracellular (Potential).					endoplasmic reticulum membrane|integral to plasma membrane	G-protein coupled receptor activity			ovary(1)|lung(1)|central_nervous_system(1)	3						CGCAAGAAACGCTGCCCCCTG	0.731000												
GRM8	2918	broad.mit.edu	37	7	126882910	126882910	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr7:126882910G>C	uc003vlr.2	-	1	660	c.349C>G	c.(349-351)CTA>GTA	p.L117V	GRM8_uc003vls.2_RNA|GRM8_uc011kof.1_RNA|GRM8_uc003vlt.2_Missense_Mutation_p.L117V|GRM8_uc010lkz.1_RNA	NM_000845	NP_000836	O00222	GRM8_HUMAN	glutamate receptor, metabotropic 8 isoform a	117	Extracellular (Potential).				negative regulation of cAMP biosynthetic process|sensory perception of smell|visual perception	integral to plasma membrane				lung(15)|ovary(5)|pancreas(1)|breast(1)|skin(1)	23		Prostate(267;0.186)			L-Glutamic Acid(DB00142)	ACGAATGTTAGAGACTGCTCC	0.488000										HNSCC(24;0.065)		
PHYHIP	9796	broad.mit.edu	37	8	22085733	22085733	+	Missense_Mutation	SNP	A	A	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr8:22085733A>C	uc003xbk.3	-	3	832	c.138T>G	c.(136-138)AAT>AAG	p.N46K	PHYHIP_uc003xbj.3_Missense_Mutation_p.N46K	NM_001099335	NP_001092805	Q92561	PHYIP_HUMAN	phytanoyl-CoA 2-hydroxylase interacting protein	46	Fibronectin type-III.										0				Colorectal(74;0.0152)|COAD - Colon adenocarcinoma(73;0.0629)		TGGAATTCTTATTCTCCTTCT	0.537000												
ANK1	286	broad.mit.edu	37	8	41548080	41548080	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr8:41548080C>T	uc003xok.2	-	32	3980	c.3896G>A	c.(3895-3897)GGG>GAG	p.G1299E	NKX6-3_uc010lxa.1_Intron|ANK1_uc003xoh.2_Missense_Mutation_p.G615E|ANK1_uc003xoi.2_Missense_Mutation_p.G1299E|ANK1_uc003xoj.2_Missense_Mutation_p.G1299E|ANK1_uc003xol.2_Missense_Mutation_p.G1299E|ANK1_uc003xom.2_Missense_Mutation_p.G1340E	NM_020476	NP_065209	P16157	ANK1_HUMAN	ankyrin 1 isoform 1	1299					axon guidance|cytoskeleton organization|exocytosis|maintenance of epithelial cell apical/basal polarity|signal transduction	basolateral plasma membrane|cytosol|sarcomere|sarcoplasmic reticulum|spectrin-associated cytoskeleton	cytoskeletal adaptor activity|enzyme binding|protein binding|spectrin binding|structural constituent of cytoskeleton			ovary(3)|central_nervous_system(3)|lung(2)|breast(1)	9	Ovarian(28;0.00541)|Colorectal(14;0.0398)|Lung SC(25;0.211)	all_lung(54;0.000626)|Lung NSC(58;0.00245)|Esophageal squamous(32;0.0559)|Hepatocellular(245;0.0663)|Renal(179;0.188)	OV - Ovarian serous cystadenocarcinoma(14;0.000984)|Lung(22;0.00108)|Colorectal(10;0.00245)|LUSC - Lung squamous cell carcinoma(45;0.00392)|COAD - Colon adenocarcinoma(11;0.0264)			CACCAGGTTCCCAGAGAGTTC	0.567000												
RP1	6101	broad.mit.edu	37	8	55533671	55533671	+	Missense_Mutation	SNP	G	G	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr8:55533671G>A	uc003xsd.1	+	2	293	c.145G>A	c.(145-147)GGC>AGC	p.G49S	RP1_uc011ldy.1_Missense_Mutation_p.G49S	NM_006269	NP_006260	P56715	RP1_HUMAN	retinitis pigmentosa RP1 protein	49	Doublecortin 1.				axoneme assembly|intracellular signal transduction|photoreceptor cell maintenance|photoreceptor cell outer segment organization|phototransduction, visible light|retinal cone cell development|retinal rod cell development	cilium axoneme|cytoplasm|microtubule|microtubule associated complex|photoreceptor connecting cilium|photoreceptor inner segment|photoreceptor outer segment	microtubule binding			skin(7)|ovary(4)|pancreas(1)	12		all_lung(136;0.0831)|Lung NSC(129;0.109)|all_epithelial(80;0.123)	OV - Ovarian serous cystadenocarcinoma(7;4.4e-07)|Epithelial(17;3.37e-05)|all cancers(17;0.000285)			CCCCCAATTCGGCGGGGTCAG	0.547000												
TMEM64	169200	broad.mit.edu	37	8	91643833	91643833	+	Nonsense_Mutation	SNP	C	C	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr8:91643833C>A	uc003yen.2	-	2	898	c.898G>T	c.(898-900)GAA>TAA	p.E300*	TMEM64_uc003yeo.2_Nonsense_Mutation_p.E39*|TMEM64_uc011lgf.1_Intron	NM_001008495	NP_001008495	Q6YI46	TMM64_HUMAN	transmembrane protein 64 isoform 1	300						integral to membrane					0			BRCA - Breast invasive adenocarcinoma(11;0.0598)			ATGACATCTTCCATTGTCCGC	0.418000												
MAMDC2	256691	broad.mit.edu	37	9	72785529	72785529	+	Missense_Mutation	SNP	G	G	C			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr9:72785529G>C	uc004ahm.2	+	11	2250	c.1633G>C	c.(1633-1635)GAT>CAT	p.D545H	MAMDC2_uc004ahn.2_RNA|uc004aho.1_Intron|uc004ahp.1_RNA	NM_153267	NP_694999	Q7Z304	MAMC2_HUMAN	MAM domain containing 2 precursor	545	MAM 4.					endoplasmic reticulum|membrane				central_nervous_system(1)|pancreas(1)	2						ACCAAAGGGAGATCACACTAC	0.463000												
AWAT1	158833	broad.mit.edu	37	X	69454559	69454559	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:69454559A>G	uc004dxy.2	+	1	55	c.14A>G	c.(13-15)AAG>AGG	p.K5R		NM_001013579	NP_001013597	Q58HT5	AWAT1_HUMAN	wax synthase 1	5					lipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	long-chain-alcohol O-fatty-acyltransferase activity			ovary(3)	3						GCTCATTCCAAGCAGCCTAGT	0.502000												
PCDH19	57526	broad.mit.edu	37	X	99662948	99662948	+	Silent	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:99662948C>T	uc010nmz.2	-	1	2324	c.648G>A	c.(646-648)CCG>CCA	p.P216P	PCDH19_uc004efw.3_Silent_p.P216P|PCDH19_uc004efx.3_Silent_p.P216P	NM_020766	NP_001098713	Q8TAB3	PCD19_HUMAN	protocadherin 19 isoform b	216	Cadherin 2.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(2)|breast(2)|upper_aerodigestive_tract(1)|urinary_tract(1)|skin(1)	7						CCAGGCGCGGCGGGTCGCCAC	0.612000												
DRP2	1821	broad.mit.edu	37	X	100490873	100490873	+	Missense_Mutation	SNP	G	G	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:100490873G>T	uc004egz.2	+	4	511	c.142G>T	c.(142-144)GCA>TCA	p.A48S	DRP2_uc011mrh.1_5'UTR	NM_001939	NP_001930	Q13474	DRP2_HUMAN	dystrophin related protein 2	48					central nervous system development	cytoplasm|cytoskeleton	zinc ion binding			ovary(2)	2						CACCAGCCCTGCACCTCCTCA	0.557000												
SLC6A14	11254	broad.mit.edu	37	X	115574828	115574828	+	Missense_Mutation	SNP	A	A	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:115574828A>G	uc004eqi.2	+	5	630	c.526A>G	c.(526-528)AGT>GGT	p.S176G	SLC6A14_uc011mtm.1_RNA	NM_007231	NP_009162	Q9UN76	S6A14_HUMAN	solute carrier family 6 (amino acid	176	Extracellular (Potential).				cellular amino acid metabolic process|response to toxin	integral to membrane	amino acid transmembrane transporter activity|neurotransmitter:sodium symporter activity			ovary(2)|pancreas(1)	3					L-Proline(DB00172)	CTGTAATGTGAGTACAGTGAA	0.323000												
ODZ1	10178	broad.mit.edu	37	X	123554435	123554435	+	Missense_Mutation	SNP	C	C	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:123554435C>T	uc004euj.2	-	24	4751	c.4687G>A	c.(4687-4689)GAC>AAC	p.D1563N	ODZ1_uc011muj.1_Missense_Mutation_p.D1569N|ODZ1_uc010nqy.2_Missense_Mutation_p.D1570N	NM_014253	NP_055068	Q9UKZ4	TEN1_HUMAN	odz, odd Oz/ten-m homolog 1 isoform 3	1563	Extracellular (Potential).				immune response|negative regulation of cell proliferation|nervous system development|signal transduction	extracellular region	heparin binding			ovary(11)|breast(4)|large_intestine(2)|skin(2)|pancreas(2)|upper_aerodigestive_tract(1)|lung(1)	23						TAAACATAGTCCCTTGTTATC	0.458000												
ATP11C	286410	broad.mit.edu	37	X	138845548	138845548	+	Silent	SNP	G	G	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:138845548G>T	uc004faz.2	-	21	2529	c.2430C>A	c.(2428-2430)GGC>GGA	p.G810G	ATP11C_uc004fax.2_Silent_p.G18G|ATP11C_uc004fay.2_RNA|ATP11C_uc004fba.2_Silent_p.G810G	NM_173694	NP_775965	Q8NB49	AT11C_HUMAN	ATPase, class VI, type 11C isoform a	810	Cytoplasmic (Potential).				ATP biosynthetic process	integral to membrane|plasma membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			ovary(5)|large_intestine(3)	8	Acute lymphoblastic leukemia(192;0.000127)					TTATTGGGCTGCCTTTTAAAT	0.378000												
GPR50	9248	broad.mit.edu	37	X	150349598	150349598	+	Missense_Mutation	SNP	C	C	A			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:150349598C>A	uc010ntg.1	+	2	1678	c.1543C>A	c.(1543-1545)CCC>ACC	p.P515T		NM_004224	NP_004215	Q13585	MTR1L_HUMAN	G protein-coupled receptor 50	515	Cytoplasmic (Potential).|Pro-rich.				cell-cell signaling	integral to plasma membrane	melatonin receptor activity			large_intestine(1)|lung(1)|ovary(1)|pancreas(1)	4	Acute lymphoblastic leukemia(192;6.56e-05)					CCATGCTGAGCCCACCACTGC	0.612000												
C1QL2	165257	broad.mit.edu	37	2	119914557	119914557	+	Splice_Site	DEL	C	C	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:119914556_119914556AC>A	uc002tlo.2	-	2	1311	c.685_splice	c.e2-1	p.V229_splice		NM_182528	NP_872334	Q7Z5L3	C1QL2_HUMAN	Homo sapiens complement component 1, q subcomponent-like 2 (C1QL2), mRNA.	229	C1q.					collagen				NS(1)|endometrium(1)|large_intestine(3)|pancreas(1)|prostate(1)	7						GCTGGCCCGGACCTGGGGACA	0.657										HNSCC(49;0.14)		
C17orf55	284185	broad.mit.edu	37	17	79279118	79279119	+	Frame_Shift_Ins	INS	-	-	G			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr17:79279118_79279119insG	uc002kac.1	-	4	475_476	c.46_47insC	c.(46-48)CGGfs	p.R16fs		NM_178519	NP_848614			hypothetical protein LOC284185												0	all_neural(118;0.0804)|Melanoma(429;0.242)		BRCA - Breast invasive adenocarcinoma(99;0.0272)|OV - Ovarian serous cystadenocarcinoma(97;0.117)			AGCAGGAGGCCGGGGGAGCAGT	0.624												
C1QL2	165257	broad.mit.edu	37	2	119914557	119914557	+	Splice_Site	DEL	C	C	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr2:119914556_119914556AC>A	uc002tlo.2	-	2	1311	c.685_splice	c.e2-1	p.V229_splice		NM_182528	NP_872334	Q7Z5L3	C1QL2_HUMAN	Homo sapiens complement component 1, q subcomponent-like 2 (C1QL2), mRNA.	229	C1q.					collagen				NS(1)|endometrium(1)|large_intestine(3)|pancreas(1)|prostate(1)	7						GCTGGCCCGGACCTGGGGACA	0.657										HNSCC(49;0.14)		
RANBP3L	202151	broad.mit.edu	37	5	36249774	36249777	+	Frame_Shift_Del	DEL	CTGT	CTGT	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr5:36249773_36249776ACTGT>A	uc011cow.2	-	14	1946_1949	c.1453_1456ACAGT>T	c.(1453-1458)cagtcgfs	p.Q485fs	RANBP3L_uc003jkh.3_Frame_Shift_Del_p.Q460fs	NM_001161429	NP_001154901	Q86VV4	RNB3L_HUMAN	Homo sapiens RAN binding protein 3-like (RANBP3L), transcript variant 1, mRNA.	460					intracellular transport			p.R459fs*>6(1)		endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(5)|ovary(1)|urinary_tract(1)	16	all_lung(31;4.52e-05)		Epithelial(62;0.0543)|Lung(74;0.111)|COAD - Colon adenocarcinoma(61;0.14)|all cancers(62;0.149)|Colorectal(62;0.202)			CAGGCAACCGACTGTCTGTGAGTC	0.319												
PCGF5	84333	broad.mit.edu	37	10	93021088	93021088	+	Frame_Shift_Del	DEL	A	A	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr10:93021087_93021087TA>T	uc001khi.3	+	6	887	c.479_479TA>T	c.(478-480)ttafs	p.L160fs	PCGF5_uc001khh.3_Frame_Shift_Del_p.L160fs|PCGF5_uc010qnk.2_Frame_Shift_Del_p.L160fs	NM_032373	NP_115749	Q86SE9	PCGF5_HUMAN	Homo sapiens polycomb group ring finger 5 (PCGF5), mRNA.	160					regulation of transcription, DNA-dependent|transcription, DNA-dependent	PcG protein complex|centrosome	zinc ion binding			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(6)	12						CTTTAGGGTTTAATGAAGAAA	0.308												
MUC6	4588	broad.mit.edu	37	11	1016412	1016414	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr11:1016411_1016413TGAG>T	uc001lsw.2	-	30	6439_6441	c.6388_6390CTCA>A	c.(6388-6390)tca>A	p.S2130del		NM_005961	NP_005952	Q6W4X9	MUC6_HUMAN	Homo sapiens mucin 6, oligomeric mucus/gel-forming (MUC6), mRNA.	2130	Ser-rich.|Thr-rich.				maintenance of gastrointestinal epithelium	extracellular region	extracellular matrix structural constituent	p.S2130delS(1)		breast(1)|central_nervous_system(1)|cervix(2)|endometrium(8)|kidney(10)|large_intestine(6)|lung(43)|ovary(4)|prostate(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	80		all_cancers(49;3.3e-08)|all_epithelial(84;5.08e-05)|Breast(177;0.000307)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.229)		all cancers(45;1.24e-24)|BRCA - Breast invasive adenocarcinoma(625;0.00031)|Lung(200;0.0576)|LUSC - Lung squamous cell carcinoma(625;0.0703)		TGGGAGAAAATGAGGAGGACAGC	0.522												
BZRAP1	9256	broad.mit.edu	37	17	56386384	56386385	+	Frame_Shift_Ins	INS	-	-	T			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chr17:56386383_56386384C>CT	uc002ivx.4	-	21	5120_5121	c.4249_4250G>AG	c.(4249-4251)agcfs	p.S1417fs	BZRAP1_uc002ivw.3_5'Flank|BZRAP1_uc010dcs.3_Frame_Shift_Ins_p.S1357fs|BZRAP1_uc010wnt.2_Frame_Shift_Ins_p.S1417fs	NM_004758	NP_004749	O95153	RIMB1_HUMAN	Homo sapiens benzodiazapine receptor (peripheral) associated protein 1 (BZRAP1), transcript variant 1, mRNA.	1417						mitochondrion	benzodiazepine receptor binding			cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|liver(2)|lung(16)|ovary(1)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	54	Medulloblastoma(34;0.127)|all_neural(34;0.237)					CCGCCTGCGGCTTGGGGGCTTC	0.653												
DDX26B	203522	broad.mit.edu	37	X	134715497	134715497	+	Frame_Shift_Del	DEL	A	A	-			TCGA-CD-8525-01A-11D-2340-08	TCGA-CD-8525-10A-01D-2341-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6b58103d-f934-4cc7-b0c1-68ce4fbbbb5e	2ca85522-f4ea-47ff-aa32-d5adbdbd1ce2	g.chrX:134715496_134715496GA>G	uc004eyw.4	+	16	2884	c.2521_2521GA>G	c.(2521-2523)gaafs	p.E841fs	DDX26B_uc004eyx.4_Frame_Shift_Del_p.E442fs	NM_182540	NP_872346	Q5JSJ4	DX26B_HUMAN	Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B (DDX26B), mRNA.	841										large_intestine(1)|lung(8)	9	Acute lymphoblastic leukemia(192;6.56e-05)					GAAGGTACTAGAAAAAATAAA	0.333												
