Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ACACB	0	genome.wustl.edu	37	12	109692128	109692128	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	109692128	109692128	G	A	SNP	ACACB	ENST00000338432	human	ensembl	74_37	+1	known	missense	c.6155	p.R2052K	1.000	pfam_Carboxyl_trans,pfscan_COA_CT_C	pfam_AcCoA_COase_cen,pfam_Carboxyl_trans,pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_CarbamoylP_synth_lsu_N,pfam_Biotin_COase_C,pfam_Biotin_lipoyl,superfamily_PreATP-grasp_dom,superfamily_Rudment_hybrid_motif,superfamily_Single_hybrid_motif,smart_Biotin_COase_C,pfscan_ATP-grasp,pfscan_Biotin_carboxylation_dom,pfscan_COA_CT_N,pfscan_COA_CT_C,pfscan_Biotin_lipoyl	-	no_errors	ACACB	HGNC	ENSG00000076555	tier1	-	-	233	0	0.00	175	24	12.00
ACAD9	0	genome.wustl.edu	37	3	128628926	128628926	+	Frame_Shift_Del	DEL	C	C	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	128628926	128628926	C	-	DEL	ACAD9	ENST00000308982	human	ensembl	74_37	+1	known	frame_shift_del	c.1626	p.M543fs	1.000	superfamily_AcylCo_DH/oxidase_C	pfam_AcylCo_DH/oxidase_C,pfam_AcylCoA_DH/ox_N,pfam_Acyl-CoA_Oxase/DH_cen-dom,pfam_Acyl-CoA_DH_2_C,superfamily_AcylCoA_DH/oxidase_NM_dom,superfamily_AcylCo_DH/oxidase_C	-	no_errors	ACAD9	HGNC	ENSG00000177646	tier1			31	0	0.00	37	2	5.13
AHDC1	0	genome.wustl.edu	37	1	27874148	27874148	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	27874148	27874148	G	A	SNP	AHDC1	ENST00000247087	human	ensembl	74_37	-1	known	silent	c.4479	p.G1493	1.000	NULL	NULL	-	no_errors	AHDC1	HGNC	ENSG00000126705				21	0	0.00	17	2	10.53
AKAP6	0	genome.wustl.edu	37	14	33291387	33291387	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	33291387	33291387	A	C	SNP	AKAP6	ENST00000280979	human	ensembl	74_37	+1	known	missense	c.4368	p.E1456D	1.000	NULL	smart_Spectrin/alpha-actinin	-	no_errors	AKAP6	HGNC	ENSG00000151320	tier1	-	-	36	0	0.00	31	8	20.51
ANK1	0	genome.wustl.edu	37	8	41526051	41526051	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	41526051	41526051	C	T	SNP	ANK1	ENST00000396942	human	ensembl	74_37	-1	known	missense	c.5128	p.V1710I	0.005	NULL	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK1	HGNC	ENSG00000029534	tier1	-	-	78	0	0.00	44	20	31.25
ANKRD33	0	genome.wustl.edu	37	12	52282975	52282975	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	52282975	52282975	A	G	SNP	ANKRD33	ENST00000340970	human	ensembl	74_37	+1	known	missense	c.116	p.Q39R	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKRD33	HGNC	ENSG00000167612	tier1	-	-	131	0	0.00	118	10	7.81
APOB	0	genome.wustl.edu	37	2	21249694	21249694	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	21249694	21249694	T	A	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	missense	c.2210	p.H737L	1.000	pfam_Vitellinogen_open_b-sht,superfamily_Lipid_transp_b-sht_shell	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674	tier1	-	-	127	0	0.00	87	16	15.53
ARHGEF9	0	genome.wustl.edu	37	X	62944558	62944558	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	62944558	62944558	C	T	SNP	ARHGEF9	ENST00000253401	human	ensembl	74_37	-1	known	missense	c.43	p.A15T	1.000	superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	pfam_DH-domain,pfam_SH3_2,pfam_SH3_domain,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_SH3_domain,smart_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain	-	no_errors	ARHGEF9	HGNC	ENSG00000131089	tier1	-	-	53	0	0.00	38	11	22.45
ATP10A	0	genome.wustl.edu	37	15	25963457	25963457	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	25963457	25963457	C	T	SNP	ATP10A	ENST00000356865	human	ensembl	74_37	-1	known	missense	c.1453	p.G485S	0.712	superfamily_HAD-like_dom,tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP10A	HGNC	ENSG00000206190				33	0	0.00	32	4	11.11
ATXN1	0	genome.wustl.edu	37	6	16326661	16326661	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	16326661	16326661	G	A	SNP	ATXN1	ENST00000244769	human	ensembl	74_37	-1	known	silent	c.1881	p.A627	0.574	pfam_Ataxin-1_HBP1,superfamily_Ataxin-1_HBP1,smart_Ataxin_AXH_dom,pfscan_Ataxin-1_HBP1	pfam_Ataxin-1_HBP1,pfam_Capicua_tscrpt_rep_mod,superfamily_Ataxin-1_HBP1,smart_Ataxin_AXH_dom,pfscan_Ataxin-1_HBP1	-	no_errors	ATXN1	HGNC	ENSG00000124788	tier1	-	-	124	0	0.00	62	11	15.07
BDNF	0	genome.wustl.edu	37	11	27679558	27679558	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	27679558	27679558	T	C	SNP	BDNF	ENST00000438929	human	ensembl	74_37	-1	known	missense	c.800	p.K267R	1.000	pfam_Nerve_growth_factor-rel,smart_Nerve_growth_factor-rel,pfscan_Nerve_growth_factor-rel,prints_Nerve_growth_factor-rel	pfam_Nerve_growth_factor-rel,smart_Nerve_growth_factor-rel,pfscan_Nerve_growth_factor-rel,prints_Brain-der_neurotrophic_factor,prints_Nerve_growth_factor-rel	-	no_errors	BDNF	HGNC	ENSG00000176697	tier1	-	-	235	0	0.00	203	18	8.14
BICC1	0	genome.wustl.edu	37	10	60560796	60560796	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	60560796	60560796	T	G	SNP	BICC1	ENST00000373886	human	ensembl	74_37	+1	known	missense	c.2005	p.S669A	1.000	NULL	pfam_KH_dom_type_1,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_KH_dom,smart_SAM,pfscan_SAM,pfscan_KH_dom_type_1	-	no_errors	BICC1	HGNC	ENSG00000122870	tier1	-	-	64	0	0.00	27	9	25.00
BICC1	0	genome.wustl.edu	37	10	60566912	60566912	+	Silent	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	60566912	60566912	T	A	SNP	BICC1	ENST00000373886	human	ensembl	74_37	+1	known	silent	c.2370	p.T790	0.332	NULL	pfam_KH_dom_type_1,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_KH_dom,smart_SAM,pfscan_SAM,pfscan_KH_dom_type_1	-	no_errors	BICC1	HGNC	ENSG00000122870	tier1	-	-	133	0	0.00	73	8	9.88
BNC1	0	genome.wustl.edu	37	15	83935597	83935597	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	83935597	83935597	G	A	SNP	BNC1	ENST00000345382	human	ensembl	74_37	-1	known	silent	c.426	p.Y142	0.046	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	BNC1	HGNC	ENSG00000169594	tier1	-	-	120	0	0.00	77	8	9.41
CACHD1	0	genome.wustl.edu	37	1	65098384	65098384	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	65098384	65098384	C	T	SNP	CACHD1	ENST00000371073	human	ensembl	74_37	+1	known	silent	c.747	p.D249	0.840	pfscan_VWF_A	pfam_VWA_N,pfam_Cache_domain,pfscan_VWF_A	-	no_errors	CACHD1	HGNC	ENSG00000158966	tier1	-	-	58	0	0.00	55	9	14.06
CAMTA1	0	genome.wustl.edu	37	1	7151399	7151399	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	7151399	7151399	C	T	SNP	CAMTA1	ENST00000303635	human	ensembl	74_37	+1	known	silent	c.270	p.H90	1.000	pfam_CG-1_dom	pfam_CG-1_dom,pfam_IPT,pfam_IQ_motif_EF-hand-BS,superfamily_Ig_E-set,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_IQ_motif_EF-hand-BS	-	no_errors	CAMTA1	HGNC	ENSG00000171735	tier1	rs146654528	-	54	0	0.00	41	8	16.33
CASQ1	0	genome.wustl.edu	37	1	160160587	160160587	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	160160587	160160587	C	T	SNP	CASQ1	ENST00000368078	human	ensembl	74_37	+1	known	missense	c.46	p.R16W	0.968	pfam_Calsequestrin	pfam_Calsequestrin,superfamily_Thioredoxin-like_fold,prints_Calsequestrin	-	no_errors	CASQ1	HGNC	ENSG00000143318				51	0	0.00	45	4	8.16
CCKBR	0	genome.wustl.edu	37	11	6291982	6291982	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	6291982	6291982	G	A	SNP	CCKBR	ENST00000525462	human	ensembl	74_37	+1	known	missense	c.760	p.D254N	0.437	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Gastrin_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Gastrin_rcpt,prints_Cholcskin_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	CCKBR	HGNC	ENSG00000110148	tier1	-	-	92	0	0.00	52	16	23.53
CCNA1	0	genome.wustl.edu	37	13	37016441	37016441	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	37016441	37016441	A	G	SNP	CCNA1	ENST00000255465	human	ensembl	74_37	+1	known	missense	c.1346	p.K449R	1.000	pfam_Cyclin_C-dom,superfamily_Cyclin-like,pirsf_Cyclin_A/B/D/E	pfam_Cyclin_N,pfam_Cyclin_C-dom,superfamily_Cyclin-like,smart_Cyclin-like,pirsf_Cyclin_A/B/D/E	-	no_errors	CCNA1	HGNC	ENSG00000133101	tier1	-	-	81	0	0.00	43	11	20.37
CLCA2	0	genome.wustl.edu	37	1	86900342	86900342	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	86900342	86900342	C	T	SNP	CLCA2	ENST00000370565	human	ensembl	74_37	+1	known	missense	c.886	p.L296F	0.916	tigrfam_CaCC_prot	pfam_Cl_channel_Ca,pfam_DUF1973,pfam_VWF_A,smart_VWF_A,pfscan_VWF_A,tigrfam_CaCC_prot	-	no_errors	CLCA2	HGNC	ENSG00000137975	tier1	-	-	122	0	0.00	111	9	7.50
COL22A1	0	genome.wustl.edu	37	8	139601449	139601449	+	RNA	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	139601449	139601449	T	G	SNP	COL22A1	ENST00000341807	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	COL22A1	HGNC	ENSG00000169436	tier1	-	-	21	0	0.00	13	7	35.00
CREBZF	0	genome.wustl.edu	37	11	85375742	85375742	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	85375742	85375742	C	T	SNP	CREBZF	ENST00000525639	human	ensembl	74_37	-1	known	missense	c.178	p.E60K	0.788	NULL	pfam_bZIP	-	no_errors	CREBZF	HGNC	ENSG00000137504	tier1	-	-	96	0	0.00	76	11	12.64
CSMD3	0	genome.wustl.edu	37	8	113871376	113871376	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	113871376	113871376	T	A	SNP	CSMD3	ENST00000297405	human	ensembl	74_37	-1	known	nonsense	c.1753	p.K585*	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD3	HGNC	ENSG00000164796	tier1	-	-	87	0	0.00	80	6	6.90
CST5	0	genome.wustl.edu	37	20	23856831	23856831	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	23856831	23856831	T	G	SNP	CST5	ENST00000304710	human	ensembl	74_37	-1	known	missense	c.423	p.K141N	0.000	NULL	pfam_Prot_inh_cystat,smart_Prot_inh_cystat	-	no_errors	CST5	HGNC	ENSG00000170367	tier1	-	-	102	0	0.00	52	28	35.00
CTNNA2	0	genome.wustl.edu	37	2	80085262	80085262	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	80085262	80085262	C	A	SNP	CTNNA2	ENST00000361291	human	ensembl	74_37	+1	known	missense	c.524	p.A175E	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA2	HGNC	ENSG00000066032	tier1	-	-	93	0	0.00	52	12	18.75
CTNNA2	0	genome.wustl.edu	37	2	80646693	80646693	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	80646693	80646693	A	G	SNP	CTNNA2	ENST00000361291	human	ensembl	74_37	+1	known	silent	c.1359	p.Q453	0.997	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA2	HGNC	ENSG00000066032	tier1	-	-	88	0	0.00	58	6	9.38
DAGLA	0	genome.wustl.edu	37	11	61487655	61487655	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	61487655	61487655	C	T	SNP	DAGLA	ENST00000257215	human	ensembl	74_37	+1	known	missense	c.28	p.R10C	1.000	NULL	pfam_Lipase_3	-	no_errors	DAGLA	HGNC	ENSG00000134780	tier1	-	-	110	0	0.00	105	7	6.25
DEFB115	0	genome.wustl.edu	37	20	29845528	29845528	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	29845528	29845528	T	G	SNP	DEFB115	ENST00000400552	human	ensembl	74_37	+1	known	missense	c.62	p.V21G	0.174	NULL	NULL	-	no_errors	DEFB115	HGNC	ENSG00000215547	tier1	-	-	110	0	0.00	63	7	10.00
DISC1	0	genome.wustl.edu	37	1	231885787	231885787	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	231885787	231885787	A	G	SNP	DISC1	ENST00000439617	human	ensembl	74_37	+1	known	silent	c.1233	p.Q411	0.350	NULL	superfamily_Prefoldin	-	no_errors	DISC1	HGNC	ENSG00000162946	tier1	-	-	113	0	0.00	86	11	11.34
DMD	0	genome.wustl.edu	37	X	32472905	32472905	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	32472905	32472905	A	G	SNP	DMD	ENST00000357033	human	ensembl	74_37	-1	known	silent	c.3477	p.T1159	0.906	pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947	tier1	-	-	70	0	0.00	57	8	12.31
EEF2	0	genome.wustl.edu	37	19	3977945	3977945	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	3977945	3977945	G	A	SNP	EEF2	ENST00000309311	human	ensembl	74_37	-1	known	missense	c.1939	p.R647C	1.000	pfam_Transl_elong_EFG/EF2_IV,superfamily_Ribosomal_S5_D2-typ_fold,smart_Transl_elong_EFG/EF2_IV	pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFG/EF2_IV,pfam_EFG_V,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_Transl_B-barrel,superfamily_EFG_III-V,smart_Transl_elong_EFG/EF2_IV,smart_EFG_V,prints_EF_GTP-bd_dom,tigrfam_Small_GTP-bd_dom	-	no_errors	EEF2	HGNC	ENSG00000167658	tier1	-	-	68	0	0.00	55	12	17.91
EIF2AK3	0	genome.wustl.edu	37	2	88890104	88890104	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	88890104	88890104	G	C	SNP	EIF2AK3	ENST00000303236	human	ensembl	74_37	-1	known	missense	c.1022	p.S341C	1.000	superfamily_Quinonprotein_ADH-like_supfam	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	EIF2AK3	HGNC	ENSG00000172071	tier1	-	-	39	0	0.00	32	4	11.11
EIF2AK3	0	genome.wustl.edu	37	2	88890409	88890409	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	88890409	88890409	A	C	SNP	EIF2AK3	ENST00000303236	human	ensembl	74_37	-1	known	missense	c.929	p.I310R	1.000	superfamily_Quinonprotein_ADH-like_supfam	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	EIF2AK3	HGNC	ENSG00000172071	tier1	-	-	166	0	0.00	132	7	5.04
EIF3J	0	genome.wustl.edu	37	15	44829395	44829397	+	In_Frame_Del	DEL	GGC	GGC	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GGC	GGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	44829395	44829397	GGC	-	DEL	EIF3J	ENST00000261868	human	ensembl	74_37	+1	known	in_frame_del	c.3_5	p.A5in_frame_del	1.000:1.000:1.000	NULL	pfam_eIF3j	-	no_errors	EIF3J	HGNC	ENSG00000104131	tier1			38	0	0.00	32	2	5.88
ELAVL2	0	genome.wustl.edu	37	9	23762204	23762204	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	9	23762204	23762204	G	A	SNP	ELAVL2	ENST00000380117	human	ensembl	74_37	-1	known	missense	c.29	p.T10I	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,prints_Hud_Sxl_RNA,tigrfam_ELAD_HUD_SF	-	no_errors	ELAVL2	HGNC	ENSG00000107105	tier1	-	-	312	0	0.00	155	42	21.32
ENSG00000271730	0	genome.wustl.edu	37	6	109319967	109319967	+	RNA	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	109319967	109319967	G	A	SNP	ENSG00000271730	ENST00000605885	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-787I22.3	Clone_based_vega_gene	ENSG00000271730	tier1	-	-	85	0	0.00	67	5	6.94
EPB41L3	0	genome.wustl.edu	37	18	5394764	5394764	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	5394764	5394764	T	C	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.3182	p.K1061R	1.000	pirsf_Band_41_protein,pfam_Band_4.1_C	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397	tier1	-	-	126	0	0.00	75	12	13.79
EPB41L3	0	genome.wustl.edu	37	18	5397201	5397201	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	5397201	5397201	C	A	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.2697	p.E899D	0.938	pirsf_Band_41_protein	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397	tier1	-	-	172	0	0.00	126	32	20.25
EPHA6	0	genome.wustl.edu	37	3	97356863	97356863	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	97356863	97356863	A	C	SNP	EPHA6	ENST00000389672	human	ensembl	74_37	+1	known	missense	c.2721	p.K907N	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	EPHA6	HGNC	ENSG00000080224	tier1	-	-	69	0	0.00	52	5	8.77
EPHB6	0	genome.wustl.edu	37	7	142567599	142567599	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	142567599	142567599	C	T	SNP	EPHB6	ENST00000392957	human	ensembl	74_37	+1	known	silent	c.2487	p.A829	0.989	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_2,pfam_SAM_type1,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHB6	HGNC	ENSG00000106123	tier1	-	-	66	0	0.00	33	7	17.50
ESF1	0	genome.wustl.edu	37	20	13740371	13740371	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	13740371	13740371	T	G	SNP	ESF1	ENST00000202816	human	ensembl	74_37	-1	known	missense	c.1796	p.N599T	1.000	NULL	pfam_NUC153	-	no_errors	ESF1	HGNC	ENSG00000089048	tier1	-	-	32	0	0.00	17	6	26.09
ESR1	0	genome.wustl.edu	37	6	152419948	152419948	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	152419948	152419948	C	T	SNP	ESR1	ENST00000206249	human	ensembl	74_37	+1	known	silent	c.1635	p.D545	0.398	superfamily_Nucl_hormone_rcpt_ligand-bd	pfam_Oestr_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Oestr_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	ESR1	HGNC	ENSG00000091831	tier1	-	-	70	0	0.00	37	6	13.95
EYA4	0	genome.wustl.edu	37	6	133844286	133844286	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	133844286	133844286	T	C	SNP	EYA4	ENST00000355167	human	ensembl	74_37	+1	known	missense	c.1709	p.I570T	1.000	pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_EYA	pfam_HAD-like_dom,superfamily_HAD-like_dom,tigrfam_EYA	-	no_errors	EYA4	HGNC	ENSG00000112319	tier1	-	-	120	0	0.00	88	5	5.38
FAM214A	0	genome.wustl.edu	37	15	52901351	52901351	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	52901351	52901351	T	G	SNP	FAM214A	ENST00000261844	human	ensembl	74_37	-1	known	missense	c.1760	p.Q587P	0.440	NULL	NULL	-	no_errors	FAM214A	HGNC	ENSG00000047346	tier1	-	-	66	0	0.00	35	7	16.67
FAM71B	0	genome.wustl.edu	37	5	156592996	156592996	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	156592996	156592996	C	A	SNP	FAM71B	ENST00000302938	human	ensembl	74_37	-1	known	missense	c.184	p.D62Y	0.989	NULL	pfam_DUF3699	-	no_errors	FAM71B	HGNC	ENSG00000170613	tier1	-	-	118	0	0.00	77	14	15.38
FAM98A	0	genome.wustl.edu	37	2	33810020	33810020	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	33810020	33810020	A	G	SNP	FAM98A	ENST00000238823	human	ensembl	74_37	-1	known	silent	c.1380	p.G460	0.997	NULL	pfam_Uncharacterised_FAM98	-	no_errors	FAM98A	HGNC	ENSG00000119812	tier1	-	-	159	0	0.00	106	8	6.96
FAT4	0	genome.wustl.edu	37	4	126372685	126372685	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	126372685	126372685	A	T	SNP	FAT4	ENST00000394329	human	ensembl	74_37	+1	known	missense	c.10514	p.D3505V	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT4	HGNC	ENSG00000196159	tier1	-	-	163	0	0.00	88	19	17.76
FCRL1	0	genome.wustl.edu	37	1	157771372	157771372	+	RNA	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	157771372	157771372	A	G	SNP	FCRL1	ENST00000368175	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	FCRL1	HGNC	ENSG00000163534	tier1	-	-	75	0	0.00	63	6	8.70
FGF14	0	genome.wustl.edu	37	13	102379052	102379052	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	102379052	102379052	A	G	SNP	FGF14	ENST00000376131	human	ensembl	74_37	-1	known	silent	c.532	p.L178	1.000	pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam	pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam,prints_Fibroblast_GF_fam,prints_IL-1_fam/FGF_fam	-	no_errors	FGF14	HGNC	ENSG00000102466	tier1	-	-	72	0	0.00	51	21	29.17
FLG2	0	genome.wustl.edu	37	1	152329419	152329419	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	152329419	152329419	A	C	SNP	FLG2	ENST00000388718	human	ensembl	74_37	-1	known	silent	c.843	p.G281	0.000	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom,prints_Filaggrin	-	no_errors	FLG2	HGNC	ENSG00000143520	tier1	-	-	266	0	0.00	172	35	16.83
FLRT2	0	genome.wustl.edu	37	14	86087886	86087886	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	86087886	86087886	A	G	SNP	FLRT2	ENST00000330753	human	ensembl	74_37	+1	known	missense	c.28	p.S10G	0.997	NULL	pfam_Leu-rich_rpt,pfam_Fibronectin_type3,pfam_LRR-contain_N,superfamily_Fibronectin_type3,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,pfscan_Fibronectin_type3	-	no_errors	FLRT2	HGNC	ENSG00000185070	tier1	-	-	111	0	0.00	70	23	24.73
FLRT2	0	genome.wustl.edu	37	14	86088396	86088396	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	86088396	86088396	G	C	SNP	FLRT2	ENST00000330753	human	ensembl	74_37	+1	known	missense	c.538	p.V180L	0.849	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,pfam_Fibronectin_type3,pfam_LRR-contain_N,superfamily_Fibronectin_type3,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,pfscan_Fibronectin_type3	-	no_errors	FLRT2	HGNC	ENSG00000185070	tier1	-	-	66	0	0.00	62	15	19.23
GRIA2	0	genome.wustl.edu	37	4	158254031	158254031	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	158254031	158254031	A	C	SNP	GRIA2	ENST00000264426	human	ensembl	74_37	+1	known	silent	c.943	p.R315	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_Iontro_glu_rcpt,pfam_ANF_lig-bd_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIA2	HGNC	ENSG00000120251	tier1	-	-	111	0	0.00	66	14	17.50
GRM7	0	genome.wustl.edu	37	3	6903293	6903293	+	Frame_Shift_Del	DEL	A	A	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	6903293	6903293	A	-	DEL	GRM7	ENST00000402647	human	ensembl	74_37	+1	known	frame_shift_del	c.218	p.N74fs	1.000	superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt_7,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_4	-	no_errors	GRM7	HGNC	ENSG00000196277	tier1			22	0	0.00	17	2	10.53
GSTA3	0	genome.wustl.edu	37	6	52761671	52761671	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	52761671	52761671	C	T	SNP	GSTA3	ENST00000211122	human	ensembl	74_37	-1	known	missense	c.602	p.G201D	1.000	superfamily_Glutathione-S-Trfase_C-like,prints_GST_alpha	pfam_Glutathione_S-Trfase_N,pfam_GST_C,superfamily_Glutathione-S-Trfase_C-like,superfamily_Thioredoxin-like_fold,prints_GST_alpha	-	no_errors	GSTA3	HGNC	ENSG00000174156	tier1	-	-	137	0	0.00	82	16	16.33
HIC1	0	genome.wustl.edu	37	17	1960405	1960407	+	In_Frame_Del	DEL	GGC	GGC	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GGC	GGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	1960405	1960407	GGC	-	DEL	HIC1	ENST00000322941	human	ensembl	74_37	+1	known	in_frame_del	c.478_480	p.G163in_frame_del	1.000:1.000:0.996	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	HIC1	HGNC	ENSG00000177374	tier1			9	0	0.00	4	2	33.33
HMCN1	0	genome.wustl.edu	37	1	185934993	185934993	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	185934993	185934993	G	A	SNP	HMCN1	ENST00000271588	human	ensembl	74_37	+1	known	missense	c.2158	p.V720I	0.051	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_G2_nidogen/fibulin_G2F,pfam_EGF-like_Ca-bd_dom,pfam_Thrombospondin_1_rpt,superfamily_GFP,superfamily_Thrombospondin_1_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_Cadherin-like,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Thrombospondin_1_rpt,smart_G2_nidogen/fibulin_G2F,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_G2_nidogen/fibulin_G2F,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom	-	no_errors	HMCN1	HGNC	ENSG00000143341	tier1	-	-	116	0	0.00	79	11	12.22
HNF4A	0	genome.wustl.edu	37	20	43052773	43052775	+	In_Frame_Del	DEL	GCT	GCT	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GCT	GCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	43052773	43052775	GCT	-	DEL	HNF4A	ENST00000316099	human	ensembl	74_37	+1	known	in_frame_del	c.1008_1010	p.L340in_frame_del	1.000:1.000:1.000	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_COUP_TF,prints_Retinoid-X_rcpt/HNF4	-	no_errors	HNF4A	HGNC	ENSG00000101076	tier1			33	0	0.00	29	3	9.38
HRNR	0	genome.wustl.edu	37	1	152186937	152186937	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	152186937	152186937	A	G	SNP	HRNR	ENST00000368801	human	ensembl	74_37	-1	known	missense	c.7168	p.S2390P	0.020	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom	-	no_errors	HRNR	HGNC	ENSG00000197915	tier1	-	-	52	0	0.00	34	7	17.07
HS3ST3B1	0	genome.wustl.edu	37	17	14248463	14248463	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	14248463	14248463	G	A	SNP	HS3ST3B1	ENST00000360954	human	ensembl	74_37	+1	known	missense	c.673	p.V225M	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST3B1	HGNC	ENSG00000125430	tier1	-	-	70	0	0.00	42	27	39.13
HS6ST3	0	genome.wustl.edu	37	13	97485087	97485087	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	97485087	97485087	T	C	SNP	HS6ST3	ENST00000376705	human	ensembl	74_37	+1	known	missense	c.1051	p.F351L	1.000	pfam_Sulfotransferase	pfam_Sulfotransferase,superfamily_P-loop_NTPase	-	no_errors	HS6ST3	HGNC	ENSG00000185352	tier1	-	-	102	0	0.00	58	9	13.43
IFNGR1	0	genome.wustl.edu	37	6	137525557	137525557	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	137525557	137525557	T	C	SNP	IFNGR1	ENST00000367739	human	ensembl	74_37	-1	known	missense	c.458	p.N153S	0.034	pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3	pfam_Interferon_gamma_pox/mammal,pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3,prints_Interferon_gamma_rcpt_asu	-	no_errors	IFNGR1	HGNC	ENSG00000027697	tier1	-	-	103	0	0.00	73	17	18.89
IGHMBP2	0	genome.wustl.edu	37	11	68675677	68675677	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	68675677	68675677	C	T	SNP	IGHMBP2	ENST00000255078	human	ensembl	74_37	+1	known	silent	c.321	p.T107	0.894	tigrfam_DNA_helicase_put	pfam_R3H_ss-bd,pfam_Znf_AN1,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_AAA+_ATPase,smart_R3H_ss-bd,smart_Znf_AN1,pfscan_Znf_AN1,pfscan_R3H_ss-bd,tigrfam_DNA_helicase_put	-	no_errors	IGHMBP2	HGNC	ENSG00000132740	tier1	-	-	150	0	0.00	135	49	26.63
IL1RAPL1	0	genome.wustl.edu	37	X	29417401	29417401	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	29417401	29417401	A	C	SNP	IL1RAPL1	ENST00000302196	human	ensembl	74_37	+1	known	silent	c.679	p.R227	1.000	smart_Ig_sub,pfscan_Ig-like_dom	pfam_TIR_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_TIR_dom,smart_Ig_sub,smart_Ig_sub2,smart_TIR_dom,pfscan_TIR_dom,pfscan_Ig-like_dom	-	no_errors	IL1RAPL1	HGNC	ENSG00000169306	tier1	-	-	27	0	0.00	21	12	36.36
IL4I1	0	genome.wustl.edu	37	19	50397635	50397635	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	50397635	50397635	T	A	SNP	IL4I1	ENST00000341114	human	ensembl	74_37	-1	known	nonsense	c.523	p.K175*	0.591	pfam_Amino_oxidase	pfam_Amino_oxidase,pfam_FAD-dep_OxRdtase,pfam_CHP00275_HI0933-like,pfam_FAD_bind_dom,pfam_Pyr_OxRdtase_NAD-bd_dom,pfam_AlaDH/PNT_NAD(H)-bd,pfam_mOase_FAD-bd,prints_Flavin_amine_oxidase	-	no_errors	IL4I1	HGNC	ENSG00000104951	tier1	-	-	112	0	0.00	92	9	8.91
IRS4	0	genome.wustl.edu	37	X	107977167	107977167	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	107977167	107977167	T	C	SNP	IRS4	ENST00000372129	human	ensembl	74_37	-1	known	missense	c.2408	p.K803R	1.000	NULL	pfam_Insln_rcpt_S1,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1,prints_Insln_rcpt_S1	-	no_errors	IRS4	HGNC	ENSG00000133124	tier1	-	-	123	0	0.00	83	37	30.83
ITGB3	0	genome.wustl.edu	37	17	45368487	45368487	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	45368487	45368487	A	C	SNP	ITGB3	ENST00000571680	human	ensembl	74_37	+1	putative	silent	c.1293	p.G431	0.000	smart_Integrin_bsu_N	pfam_Integrin_bsu_N,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,prints_Integrin_bsu	-	no_errors	ITGB3	HGNC	ENSG00000259207	tier1	-	-	76	0	0.00	52	5	8.62
KIAA1109	0	genome.wustl.edu	37	4	123130419	123130419	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	123130419	123130419	A	C	SNP	KIAA1109	ENST00000264501	human	ensembl	74_37	+1	known	missense	c.1858	p.T620P	0.020	NULL	pfam_Fragile_site-assoc_C	-	no_errors	KIAA1109	HGNC	ENSG00000138688				70	0	0.00	26	3	10.34
KIF14	0	genome.wustl.edu	37	1	200534591	200534591	+	Missense_Mutation	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	200534591	200534591	C	G	SNP	KIF14	ENST00000367350	human	ensembl	74_37	-1	known	missense	c.3868	p.E1290Q	1.000	NULL	pfam_Kinesin_motor_dom,pfam_FHA_dom,superfamily_P-loop_NTPase,superfamily_SMAD_FHA_domain,smart_Kinesin_motor_dom,smart_FHA_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF14	HGNC	ENSG00000118193	tier1	-	-	39	0	0.00	30	4	11.76
KRT34	0	genome.wustl.edu	37	17	39535241	39535241	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	39535241	39535241	G	A	SNP	KRT34	ENST00000394001	human	ensembl	74_37	-1	known	missense	c.1190	p.T397M	0.864	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT34	HGNC	ENSG00000131737	tier1	-	-	198	0	0.00	133	22	14.19
KRT6B	0	genome.wustl.edu	37	12	52840977	52840977	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	52840977	52840977	G	A	SNP	KRT6B	ENST00000252252	human	ensembl	74_37	-1	known	silent	c.1692	p.H564	0.192	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT6B	HGNC	ENSG00000185479	tier1	-	-	119	0	0.00	83	14	14.43
KSR2	0	genome.wustl.edu	37	12	117962864	117962864	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	117962864	117962864	A	T	SNP	KSR2	ENST00000339824	human	ensembl	74_37	-1	known	missense	c.2012	p.L671H	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	KSR2	HGNC	ENSG00000171435	tier1	-	-	60	0	0.00	34	5	12.82
LIMCH1	0	genome.wustl.edu	37	4	41648507	41648507	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	41648507	41648507	G	A	SNP	LIMCH1	ENST00000503057	human	ensembl	74_37	+1	known	missense	c.2417	p.R806Q	1.000	NULL	pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	LIMCH1	HGNC	ENSG00000064042	tier1	rs140689582	-	109	0	0.00	79	11	12.09
LOC101929006	0	genome.wustl.edu	37	6	29231769	29231769	+	RNA	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	29231769	29231769	A	C	SNP	LOC101929006	ENST00000441381	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.021	-	-	-	no_errors	XXbac-BPG308J9.3	Clone_based_vega_gene	ENSG00000232505	tier1	-	-	117	0	0.00	92	12	11.54
LRP12	0	genome.wustl.edu	37	8	105502952	105502952	+	Silent	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	105502952	105502952	T	C	SNP	LRP12	ENST00000424843	human	ensembl	74_37	-1	known	silent	c.2472	p.E824	0.977	NULL	pfam_CUB_dom,pfam_LDrepeatLR_classA_rpt,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_LDrepeatLR_classA_rpt,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP12	HGNC	ENSG00000147650	tier1	-	-	118	0	0.00	66	7	9.59
LRP1B	0	genome.wustl.edu	37	2	141259339	141259339	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	141259339	141259339	T	A	SNP	LRP1B	ENST00000389484	human	ensembl	74_37	-1	known	nonsense	c.8767	p.R2923*	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EG-like_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1B	HGNC	ENSG00000168702	tier1	-	-	71	0	0.00	45	9	16.67
LRRTM4	0	genome.wustl.edu	37	2	77746793	77746793	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	77746793	77746793	A	C	SNP	LRRTM4	ENST00000409911	human	ensembl	74_37	-1	known	missense	c.205	p.L69V	0.052	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRTM4	HGNC	ENSG00000176204	tier1	-	-	117	0	0.00	69	11	13.75
MAD1L1	0	genome.wustl.edu	37	7	2054206	2054206	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	2054206	2054206	C	A	SNP	MAD1L1	ENST00000265854	human	ensembl	74_37	-1	known	missense	c.1290	p.Q430H	1.000	pfam_Mad1	pfam_Mad1	-	no_errors	MAD1L1	HGNC	ENSG00000002822	tier1	-	-	53	0	0.00	42	5	10.64
MAGEC1	0	genome.wustl.edu	37	X	140993285	140993285	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	140993285	140993285	A	G	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	missense	c.95	p.Q32R	1.000	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495	tier1	-	-	88	0	0.00	48	38	44.19
MAGEC3	0	genome.wustl.edu	37	X	140969448	140969448	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	140969448	140969448	A	G	SNP	MAGEC3	ENST00000298296	human	ensembl	74_37	+1	known	missense	c.775	p.T259A	0.021	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC3	HGNC	ENSG00000165509	tier1	-	-	129	0	0.00	61	28	31.46
MAP3K9	0	genome.wustl.edu	37	14	71275774	71275776	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	CCT	CCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	71275774	71275776	CCT	-	DEL	MAP3K9	ENST00000555993	human	ensembl	74_37	-1	known	in_frame_del	c.115_113	p.E38in_frame_del	1.000:1.000:0.998	pirsf_MAPKKK9/10/11	pirsf_MAPKKK9/10/11,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH3_2,pfam_SH3_domain,superfamily_Kinase-like_dom,superfamily_SH3_domain,superfamily_Regulat_G_prot_signal_superfam,smart_SH3_domain,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH3_domain,pfscan_SH3_domain,pfscan_Prot_kinase_dom	-	no_errors	MAP3K9	HGNC	ENSG00000006432	tier1			9	0	0.00	6	3	33.33
MB21D2	0	genome.wustl.edu	37	3	192517008	192517008	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	192517008	192517008	T	C	SNP	MB21D2	ENST00000392452	human	ensembl	74_37	-1	known	missense	c.643	p.K215E	1.000	NULL	pfam_Mab-21_dom	-	no_errors	MB21D2	HGNC	ENSG00000180611	tier1	-	-	98	0	0.00	85	6	6.59
MED12L	0	genome.wustl.edu	37	3	150883667	150883667	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	150883667	150883667	A	C	SNP	MED12L	ENST00000474524	human	ensembl	74_37	+1	known	missense	c.1392	p.E464D	1.000	pfam_Mediator_Med12_LCEWAV	pfam_Mediator_Med12_LCEWAV,pfam_Mediator_Med12,pfam_Mediator_Med12_catenin-bd	-	no_errors	MED12L	HGNC	ENSG00000144893	tier1	-	-	167	0	0.00	145	9	5.84
MFNG	0	genome.wustl.edu	37	22	37876306	37876306	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	22	37876306	37876306	C	T	SNP	MFNG	ENST00000438891	human	ensembl	74_37	-1	known	missense	c.287	p.R96Q	0.002	NULL	pfam_Fringe-like	-	no_errors	MFNG	HGNC	ENSG00000100060	tier1	-	-	66	0	0.00	51	6	10.53
MGAT2	0	genome.wustl.edu	37	14	50089217	50089220	+	Frame_Shift_Del	DEL	CTAA	CTAA	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	CTAA	CTAA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	50089217	50089220	CTAA	-	DEL	MGAT2	ENST00000305386	human	ensembl	74_37	+1	known	frame_shift_del	c.1231_1234	p.T412fs	0.982:0.985:0.001:0.000	pfam_GlcNAc_II	pfam_GlcNAc_II	-	no_errors	MGAT2	HGNC	ENSG00000168282	tier1			83	0	0.00	48	7	12.73
MIR1200	0	genome.wustl.edu	37	7	36958970	36958970	+	RNA	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	36958970	36958970	C	T	SNP	MIR1200	ENST00000408398	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR1200	HGNC	ENSG00000221325	tier1	-	-	70	0	0.00	36	10	21.74
MOGAT1	0	genome.wustl.edu	37	2	223559200	223559200	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	223559200	223559200	T	C	SNP	MOGAT1	ENST00000446656	human	ensembl	74_37	+1	known	missense	c.598	p.F200L	0.002	pfam_DAGAT	pfam_DAGAT	-	no_errors	MOGAT1	HGNC	ENSG00000124003	tier1	-	-	58	0	0.00	28	6	17.65
MYT1L	0	genome.wustl.edu	37	2	1812914	1812914	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	1812914	1812914	A	C	SNP	MYT1L	ENST00000399161	human	ensembl	74_37	-1	known	missense	c.3106	p.S1036A	0.993	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1L	HGNC	ENSG00000186487	tier1	-	-	166	0	0.00	107	11	9.32
NLRP9	0	genome.wustl.edu	37	19	56241343	56241343	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	56241343	56241343	G	A	SNP	NLRP9	ENST00000332836	human	ensembl	74_37	-1	known	silent	c.1848	p.L616	0.000	NULL	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP9	HGNC	ENSG00000185792	tier1	-	-	108	0	0.00	77	12	13.48
NPEPPS	0	genome.wustl.edu	37	17	45668087	45668087	+	Nonsense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	45668087	45668087	G	A	SNP	NPEPPS	ENST00000322157	human	ensembl	74_37	+1	known	nonsense	c.1100	p.W367*	1.000	pfam_Peptidase_M1_N	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	NPEPPS	HGNC	ENSG00000141279	tier1	-	-	35	0	0.00	22	3	12.00
NPHS1	0	genome.wustl.edu	37	19	36317473	36317473	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	36317473	36317473	G	T	SNP	NPHS1	ENST00000378910	human	ensembl	74_37	-1	known	missense	c.3669	p.D1223E	0.130	NULL	pfam_CD80_C2-set,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	NPHS1	HGNC	ENSG00000161270	tier1	-	-	70	0	0.00	44	11	20.00
NR1H4	0	genome.wustl.edu	37	12	100904824	100904824	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	100904824	100904824	G	A	SNP	NR1H4	ENST00000551379	human	ensembl	74_37	+1	known	silent	c.378	p.A126	0.000	prints_ThyrH_rcpt	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_ThyrH_rcpt	-	no_errors	NR1H4	HGNC	ENSG00000012504	tier1	-	-	117	0	0.00	108	10	8.47
NUMA1	0	genome.wustl.edu	37	11	71726700	71726700	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	71726700	71726700	G	A	SNP	NUMA1	ENST00000393695	human	ensembl	74_37	-1	known	silent	c.1849	p.L617	0.805	NULL	superfamily_Prefoldin	-	no_errors	NUMA1	HGNC	ENSG00000137497	tier1	-	-	50	0	0.00	51	13	20.31
NYNRIN	0	genome.wustl.edu	37	14	24885245	24885245	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	24885245	24885245	C	T	SNP	NYNRIN	ENST00000382554	human	ensembl	74_37	+1	known	silent	c.4290	p.T1430	1.000	superfamily_RNaseH-like_dom	pfam_RNase_Zc3h12,superfamily_RNaseH-like_dom,pfscan_Integrase_cat-core	-	no_errors	NYNRIN	HGNC	ENSG00000205978	tier1	-	-	124	0	0.00	95	8	7.77
OR4D5	0	genome.wustl.edu	37	11	123811018	123811018	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	123811018	123811018	G	T	SNP	OR4D5	ENST00000307033	human	ensembl	74_37	+1	known	missense	c.695	p.G232V	0.965	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4D5	HGNC	ENSG00000171014	tier1	-	-	278	0	0.00	282	16	5.37
OR4K5	0	genome.wustl.edu	37	14	20388990	20388990	+	Silent	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	20388990	20388990	T	A	SNP	OR4K5	ENST00000315915	human	ensembl	74_37	+1	known	silent	c.225	p.S75	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4K5	HGNC	ENSG00000176281	tier1	-	-	415	0	0.00	314	45	12.50
OR4N5	0	genome.wustl.edu	37	14	20612517	20612517	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	20612517	20612517	T	G	SNP	OR4N5	ENST00000333629	human	ensembl	74_37	+1	known	missense	c.623	p.L208R	0.180	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	OR4N5	HGNC	ENSG00000184394	tier1	-	-	95	0	0.00	56	8	12.50
OR4Q3	0	genome.wustl.edu	37	14	20216395	20216395	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	20216395	20216395	A	C	SNP	OR4Q3	ENST00000331723	human	ensembl	74_37	+1	known	missense	c.809	p.K270T	0.580	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4Q3	HGNC	ENSG00000182652	tier1	-	-	178	0	0.00	122	23	15.86
OR5D16	0	genome.wustl.edu	37	11	55606311	55606311	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	55606311	55606311	C	T	SNP	OR5D16	ENST00000378396	human	ensembl	74_37	+1	known	silent	c.84	p.P28	0.048	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5D16	HGNC	ENSG00000205029	tier1	-	-	128	0	0.00	127	12	8.63
OR8H3	0	genome.wustl.edu	37	11	55890034	55890034	+	Silent	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	55890034	55890034	T	C	SNP	OR8H3	ENST00000313472	human	ensembl	74_37	+1	known	silent	c.186	p.F62	0.934	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8H3	HGNC	ENSG00000181761	tier1	-	-	491	0	0.00	363	77	17.50
PARP4	0	genome.wustl.edu	37	13	25066627	25066627	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	25066627	25066627	G	C	SNP	PARP4	ENST00000381989	human	ensembl	74_37	-1	known	missense	c.985	p.P329A	0.996	superfamily_Poly(ADP-ribose)pol_reg_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	pfam_Poly(ADP-ribose)pol_cat_dom,pfam_VIT,pfam_VWF_A,pfam_BRCT_dom,superfamily_Poly(ADP-ribose)pol_reg_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_VIT,smart_VWF_A,pfscan_BRCT_dom,pfscan_VWF_A,pfscan_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	-	no_errors	PARP4	HGNC	ENSG00000102699	tier1	-	-	124	0	0.00	90	6	6.25
PCDH15	0	genome.wustl.edu	37	10	55566868	55566868	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	55566868	55566868	T	G	SNP	PCDH15	ENST00000414778	human	ensembl	74_37	-1	known	missense	c.4517	p.K1506T	1.000	NULL	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275	tier1	-	-	29	0	0.00	19	5	20.83
PCDH15	0	genome.wustl.edu	37	10	55973754	55973754	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	55973754	55973754	A	G	SNP	PCDH15	ENST00000320301	human	ensembl	74_37	-1	known	missense	c.1040	p.L347P	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275	tier1	-	-	55	0	0.00	67	10	12.99
PDE3A	0	genome.wustl.edu	37	12	20801740	20801740	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	20801740	20801740	A	T	SNP	PDE3A	ENST00000359062	human	ensembl	74_37	+1	known	missense	c.2684	p.K895M	1.000	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	-	no_errors	PDE3A	HGNC	ENSG00000172572	tier1	-	-	125	0	0.00	77	9	10.47
PIFO	0	genome.wustl.edu	37	1	111891299	111891300	+	RNA	INS	-	-	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	111891299	111891300	-	A	INS	PIFO	ENST00000484512	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.001	-	-	-	no_errors	PIFO	HGNC	ENSG00000173947	tier1			289	0	0.00	172	16	8.51
PIGZ	0	genome.wustl.edu	37	3	196674046	196674046	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	196674046	196674046	C	T	SNP	PIGZ	ENST00000412723	human	ensembl	74_37	-1	known	silent	c.1722	p.E574	0.997	NULL	pfam_GPI_mannosylTrfase	-	no_errors	PIGZ	HGNC	ENSG00000119227	tier1	-	-	89	0	0.00	87	5	5.43
PRAMEF22	0	genome.wustl.edu	37	1	13036458	13036458	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	13036458	13036458	G	A	SNP	PRAMEF22	ENST00000376187	human	ensembl	74_37	+1	known	missense	c.530	p.R177K	0.015	NULL	NULL	-	no_errors	PRAMEF22	HGNC	ENSG00000204508	tier1	-	-	78	0	0.00	54	14	20.59
RB1	0	genome.wustl.edu	37	13	48919318	48919318	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	48919318	48919318	C	G	SNP	RB1	ENST00000267163	human	ensembl	74_37	+1	known	silent	c.483	p.L161	0.995	pfam_RB_N	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687	tier1	-	-	97	0	0.00	62	11	15.07
RP1L1	0	genome.wustl.edu	37	8	10466100	10466100	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	10466100	10466100	C	T	SNP	RP1L1	ENST00000382483	human	ensembl	74_37	-1	known	silent	c.5508	p.E1836	0.004	NULL	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	-	no_errors	RP1L1	HGNC	ENSG00000183638	tier1	-	-	377	0	0.00	241	26	9.74
RTN3	0	genome.wustl.edu	37	11	63487821	63487821	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	63487821	63487821	C	T	SNP	RTN3	ENST00000377819	human	ensembl	74_37	+1	known	missense	c.1847	p.S616F	0.217	NULL	pfam_Reticulon,pfscan_Reticulon	-	no_errors	RTN3	HGNC	ENSG00000133318	tier1	-	-	109	0	0.00	129	7	5.15
RUNX1	0	genome.wustl.edu	37	21	36228727	36228727	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	21	36228727	36228727	G	A	SNP	RUNX1	ENST00000486278	human	ensembl	74_37	-1	known	missense	c.559	p.R187W	0.001	NULL	pfam_Runt_dom,superfamily_p53-like_TF_DNA-bd,pfscan_Runt_dom,prints_AML1_Runt	-	no_errors	RUNX1	HGNC	ENSG00000159216				53	0	0.00	34	4	10.53
SEMA6A	0	genome.wustl.edu	37	5	115815859	115815859	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	115815859	115815859	G	A	SNP	SEMA6A	ENST00000257414	human	ensembl	74_37	-1	known	silent	c.1209	p.P403	0.613	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom	-	no_errors	SEMA6A	HGNC	ENSG00000092421	tier1	-	-	90	0	0.00	50	8	13.79
SERPINI1	0	genome.wustl.edu	37	3	167508347	167508347	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	167508347	167508347	C	G	SNP	SERPINI1	ENST00000295777	human	ensembl	74_37	+1	known	silent	c.438	p.A146	0.601	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	-	no_errors	SERPINI1	HGNC	ENSG00000163536	tier1	-	-	57	0	0.00	41	8	16.33
SI	0	genome.wustl.edu	37	3	164709237	164709237	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	164709237	164709237	A	C	SNP	SI	ENST00000264382	human	ensembl	74_37	-1	known	missense	c.5012	p.F1671C	0.000	pfam_Glyco_hydro_31	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	SI	HGNC	ENSG00000090402	tier1	-	-	50	0	0.00	42	4	8.70
SI	0	genome.wustl.edu	37	3	164735779	164735779	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	164735779	164735779	A	G	SNP	SI	ENST00000264382	human	ensembl	74_37	-1	known	silent	c.3499	p.L1167	0.691	superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	SI	HGNC	ENSG00000090402	tier1	-	-	93	0	0.00	67	6	8.22
SLC10A6	0	genome.wustl.edu	37	4	87769921	87769921	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	87769921	87769921	G	A	SNP	SLC10A6	ENST00000273905	human	ensembl	74_37	-1	known	silent	c.348	p.T116	1.000	pfam_BilAc/Na_symport,tigrfam_Bil_ac_transpt	pfam_BilAc/Na_symport,tigrfam_Bil_ac_transpt	-	no_errors	SLC10A6	HGNC	ENSG00000145283	tier1	-	-	125	0	0.00	104	19	15.45
SLC17A6	0	genome.wustl.edu	37	11	22363082	22363082	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	22363082	22363082	A	C	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.95	p.E32A	1.000	superfamily_MFS_dom_general_subst_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664	tier1	-	-	135	0	0.00	112	8	6.67
SLC23A3	0	genome.wustl.edu	37	2	220028979	220028980	+	Frame_Shift_Ins	INS	-	-	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	220028979	220028980	-	G	INS	SLC23A3	ENST00000455516	human	ensembl	74_37	-1	known	frame_shift_ins	c.1273_1272	p.T424fs	0.998:0.996	pfam_Xant/urac/vitC	pfam_Xant/urac/vitC	-	no_errors	SLC23A3	HGNC	ENSG00000213901	tier1			17	0	0.00	9	2	18.18
SLC39A12	0	genome.wustl.edu	37	10	18242355	18242355	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	18242355	18242355	C	G	SNP	SLC39A12	ENST00000377369	human	ensembl	74_37	+1	known	silent	c.150	p.L50	0.954	NULL	pfam_ZIP	-	no_errors	SLC39A12	HGNC	ENSG00000148482	tier1	-	-	84	0	0.00	77	5	6.10
SLC39A12	0	genome.wustl.edu	37	10	18250710	18250710	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	18250710	18250710	A	C	SNP	SLC39A12	ENST00000377369	human	ensembl	74_37	+1	known	missense	c.462	p.E154D	1.000	NULL	pfam_ZIP	-	no_errors	SLC39A12	HGNC	ENSG00000148482	tier1	-	-	74	0	0.00	60	16	21.05
SNTG1	0	genome.wustl.edu	37	8	51415430	51415430	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	51415430	51415430	A	C	SNP	SNTG1	ENST00000518864	human	ensembl	74_37	+1	known	missense	c.456	p.E152D	1.000	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,smart_Pleckstrin_homology,pfscan_PDZ,pfscan_Pleckstrin_homology	-	no_errors	SNTG1	HGNC	ENSG00000147481	tier1	-	-	59	0	0.00	35	4	10.26
SOX30	0	genome.wustl.edu	37	5	157065334	157065334	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	157065334	157065334	G	-	DEL	SOX30	ENST00000265007	human	ensembl	74_37	-1	known	frame_shift_del	c.1784	p.P595fs	0.919	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	SOX30	HGNC	ENSG00000039600	tier1			65	0	0.00	37	2	5.13
SRMS	0	genome.wustl.edu	37	20	62178476	62178476	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	62178476	62178476	G	A	SNP	SRMS	ENST00000217188	human	ensembl	74_37	-1	known	missense	c.341	p.T114M	0.001	superfamily_SH3_domain	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH2,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_SH2,pfscan_SH3_domain,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH2	-	no_errors	SRMS	HGNC	ENSG00000125508				93	0	0.00	80	5	5.88
SSX5	0	genome.wustl.edu	37	X	48053653	48053653	+	Missense_Mutation	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	48053653	48053653	C	G	SNP	SSX5	ENST00000311798	human	ensembl	74_37	-1	known	missense	c.315	p.K105N	0.000	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	pfam_SSXRD_motif,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	-	no_errors	SSX5	HGNC	ENSG00000165583	tier1	-	-	72	0	0.00	61	17	21.79
SUPT6H	0	genome.wustl.edu	37	17	27001303	27001305	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GAG	GAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	27001303	27001305	GAG	-	DEL	SUPT6H	ENST00000314616	human	ensembl	74_37	+1	known	in_frame_del	c.112_114	p.E41in_frame_del	1.000:1.000:0.998	pirsf_TF_Spt6	pfam_Rbsml_prot_S1_RNA-bd_dom,pfam_SH2,superfamily_NA-bd_OB-fold,smart_YqgF/RNaseH-like_dom,smart_RNA-binding_domain_S1,smart_SH2,pirsf_TF_Spt6,pfscan_SH2,pfscan_Rbsml_prot_S1_RNA-bd_dom	-	no_errors	SUPT6H	HGNC	ENSG00000109111	tier1			48	0	0.00	35	2	5.41
SYMPK	0	genome.wustl.edu	37	19	46347310	46347310	+	Silent	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	46347310	46347310	G	T	SNP	SYMPK	ENST00000245934	human	ensembl	74_37	-1	known	silent	c.825	p.I275	1.000	pfam_DUF3453,superfamily_ARM-type_fold	pfam_DUF3453,pfam_Symplekin_C,superfamily_ARM-type_fold	-	no_errors	SYMPK	HGNC	ENSG00000125755	tier1	-	-	125	0	0.00	46	7	13.21
TNR	0	genome.wustl.edu	37	1	175336377	175336377	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	175336377	175336377	G	T	SNP	TNR	ENST00000263525	human	ensembl	74_37	-1	known	missense	c.2020	p.Q674K	1.000	superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNR	HGNC	ENSG00000116147	tier1	-	-	74	0	0.00	59	9	13.24
TRAPPC8	0	genome.wustl.edu	37	18	29437875	29437875	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	29437875	29437875	T	C	SNP	TRAPPC8	ENST00000283351	human	ensembl	74_37	-1	known	missense	c.2816	p.N939S	1.000	NULL	NULL	-	no_errors	TRAPPC8	HGNC	ENSG00000153339	tier1	-	-	227	0	0.00	140	33	18.97
TRMT10A	0	genome.wustl.edu	37	4	100477328	100477328	+	Frame_Shift_Del	DEL	T	T	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	100477328	100477328	T	-	DEL	TRMT10A	ENST00000273962	human	ensembl	74_37	-1	known	frame_shift_del	c.470	p.N157fs	1.000	pfam_tRNA_m1G_MeTrfase,pirsf_tRNA_MeTfrase_TRM10	pfam_tRNA_m1G_MeTrfase,pirsf_tRNA_MeTfrase_TRM10	-	no_errors	TRMT10A	HGNC	ENSG00000145331	tier1			52	0	0.00	35	2	5.41
TTLL12	0	genome.wustl.edu	37	22	43570378	43570378	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	22	43570378	43570378	G	A	SNP	TTLL12	ENST00000216129	human	ensembl	74_37	-1	known	silent	c.1066	p.L356	1.000	pfam_TTL/TTLL_fam	pfam_TTL/TTLL_fam	-	no_errors	TTLL12	HGNC	ENSG00000100304	tier1	-	-	75	0	0.00	49	8	14.04
TTN	0	genome.wustl.edu	37	2	179416419	179416419	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	179416419	179416419	T	C	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.83504	p.N27835S	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	60	0	0.00	53	6	10.17
UBA6-AS1	0	genome.wustl.edu	37	4	68928905	68928905	+	RNA	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	68928905	68928905	A	C	SNP	UBA6-AS1	ENST00000499180	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	UBA6-AS1	HGNC	ENSG00000248049	tier1	-	-	73	0	0.00	55	12	17.91
UNC5D	0	genome.wustl.edu	37	8	35583918	35583918	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	35583918	35583918	T	A	SNP	UNC5D	ENST00000404895	human	ensembl	74_37	+1	known	missense	c.1552	p.F518I	0.996	NULL	pfam_ZU5,pfam_Ig_I-set,pfam_Thrombospondin_1_rpt,pfam_Death_domain,pfam_Immunoglobulin,superfamily_DEATH-like_dom,superfamily_Thrombospondin_1_rpt,smart_Ig_sub,smart_Ig_sub2,smart_Thrombospondin_1_rpt,smart_ZU5,smart_Death_domain,pfscan_Thrombospondin_1_rpt,pfscan_ZU5,pfscan_Ig-like_dom	-	no_errors	UNC5D	HGNC	ENSG00000156687	tier1	-	-	128	0	0.00	69	17	19.77
VEPH1	0	genome.wustl.edu	37	3	156983365	156983365	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	156983365	156983365	G	A	SNP	VEPH1	ENST00000362010	human	ensembl	74_37	-1	known	missense	c.2215	p.R739C	1.000	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Pleckstrin_homology,superfamily_ARM-type_fold,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	VEPH1	HGNC	ENSG00000197415	tier1	rs151166199	-	70	0	0.00	61	6	8.96
WDR83	0	genome.wustl.edu	37	19	12781077	12781077	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	12781077	12781077	G	A	SNP	WDR83	ENST00000242796	human	ensembl	74_37	+1	known	missense	c.308	p.R103H	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	WDR83	HGNC	ENSG00000123154	tier1	-	-	173	0	0.00	120	19	13.67
ZBTB40	0	genome.wustl.edu	37	1	22817021	22817021	+	Nonsense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	22817021	22817021	C	T	SNP	ZBTB40	ENST00000375647	human	ensembl	74_37	+1	known	nonsense	c.580	p.Q194*	0.958	NULL	pfam_Znf_C2H2,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB40	HGNC	ENSG00000184677	tier1	-	-	210	0	0.00	166	17	9.29
ZBTB9	0	genome.wustl.edu	37	6	33423797	33423797	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	33423797	33423797	A	G	SNP	ZBTB9	ENST00000395064	human	ensembl	74_37	+1	known	missense	c.920	p.K307R	0.909	NULL	pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB9	HGNC	ENSG00000213588	tier1	-	-	136	0	0.00	112	10	8.20
ZFYVE1	0	genome.wustl.edu	37	14	73464684	73464684	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	73464684	73464684	C	T	SNP	ZFYVE1	ENST00000553891	human	ensembl	74_37	-1	known	missense	c.823	p.D275N	1.000	superfamily_P-loop_NTPase,superfamily_Growth_fac_rcpt_N_dom	pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,superfamily_P-loop_NTPase,superfamily_Growth_fac_rcpt_N_dom,smart_Znf_FYVE,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE1	HGNC	ENSG00000165861	tier1	-	-	91	0	0.00	65	14	17.72
ZIM2	0	genome.wustl.edu	37	19	57286620	57286620	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	57286620	57286620	T	G	SNP	ZIM2	ENST00000221722	human	ensembl	74_37	-1	known	missense	c.1020	p.Q340H	0.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Krueppel-associated_box,pfam_Znf_C2H2,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZIM2	HGNC	ENSG00000269699	tier1	-	-	91	0	0.00	65	11	14.29
ZNF100	0	genome.wustl.edu	37	19	21926888	21926888	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	21926888	21926888	T	A	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	missense	c.253	p.I85F	0.073	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020	tier1	-	-	158	0	0.00	82	17	17.17
FLG2	0	genome.wustl.edu	37	1	152329419	152329419	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	152329419	152329419	A	C	SNP	FLG2	ENST00000388718	human	ensembl	74_37	-1	known	silent	c.843	p.G281	0.000	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom,prints_Filaggrin	-	no_errors	FLG2	HGNC	ENSG00000143520				247	0	0	157	31	16.4894
CASQ1	0	genome.wustl.edu	37	1	160160587	160160587	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	160160587	160160587	C	T	SNP	CASQ1	ENST00000368078	human	ensembl	74_37	+1	known	missense	c.46	p.R16W	0.968	pfam_Calsequestrin	pfam_Calsequestrin,superfamily_Thioredoxin-like_fold,prints_Calsequestrin	-	no_errors	CASQ1	HGNC	ENSG00000143318				45	0	0	40	3	6.97674
TNR	0	genome.wustl.edu	37	1	175336377	175336377	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	175336377	175336377	G	T	SNP	TNR	ENST00000263525	human	ensembl	74_37	-1	known	missense	c.2020	p.Q674K	1.000	superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNR	HGNC	ENSG00000116147				64	0	0	51	7	12.069
HMCN1	0	genome.wustl.edu	37	1	185934993	185934993	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	185934993	185934993	G	A	SNP	HMCN1	ENST00000271588	human	ensembl	74_37	+1	known	missense	c.2158	p.V720I	0.051	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_G2_nidogen/fibulin_G2F,pfam_EGF-like_Ca-bd_dom,pfam_Thrombospondin_1_rpt,superfamily_GFP,superfamily_Thrombospondin_1_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_Cadherin-like,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Thrombospondin_1_rpt,smart_G2_nidogen/fibulin_G2F,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_G2_nidogen/fibulin_G2F,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom	-	no_errors	HMCN1	HGNC	ENSG00000143341				98	0	0	68	9	11.6883
RGS18	0	genome.wustl.edu	37	1	192150478	192150478	+	Nonsense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	192150478	192150478	G	T	SNP	RGS18	ENST00000367460	human	ensembl	74_37	+1	known	nonsense	c.340	p.E114*	1.000	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS18	HGNC	ENSG00000150681				62	0	0	36	4	10
KCNT2	0	genome.wustl.edu	37	1	196227371	196227371	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	196227371	196227371	A	G	SNP	KCNT2	ENST00000294725	human	ensembl	74_37	-1	known	missense	c.3164	p.L1055P	1.000	NULL	pfam_K_chnl_Ca-activ_BK_asu,pfam_2pore_dom_K_chnl_dom	-	no_errors	KCNT2	HGNC	ENSG00000162687				80	0	0	56	3	5.08475
ZBTB40	0	genome.wustl.edu	37	1	22817021	22817021	+	Nonsense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	22817021	22817021	C	T	SNP	ZBTB40	ENST00000375647	human	ensembl	74_37	+1	known	nonsense	c.580	p.Q194*	0.958	NULL	pfam_Znf_C2H2,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB40	HGNC	ENSG00000184677				195	0	0	152	16	9.52381
DISC1	0	genome.wustl.edu	37	1	231885787	231885787	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	231885787	231885787	A	G	SNP	DISC1	ENST00000439617	human	ensembl	74_37	+1	known	silent	c.1233	p.Q411	0.350	NULL	superfamily_Prefoldin	-	no_errors	DISC1	HGNC	ENSG00000162946				96	0	0	76	10	11.6279
OR2M3	0	genome.wustl.edu	37	1	248366676	248366676	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	248366676	248366676	T	G	SNP	OR2M3	ENST00000456743	human	ensembl	74_37	+1	known	missense	c.307	p.F103V	0.821	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2M3	HGNC	ENSG00000228198				396	1	0.251889	264	50	15.9236
TTC39A	0	genome.wustl.edu	37	1	51753878	51753878	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	51753878	51753878	G	C	SNP	TTC39A	ENST00000447632	human	ensembl	74_37	-1	known	missense	c.1793	p.S598C	0.992	NULL	pfam_OMP_IML2_mit/TPR_39,smart_TPR_repeat	-	no_errors	TTC39A	HGNC	ENSG00000085831				60	0	0	51	3	5.55556
CACHD1	0	genome.wustl.edu	37	1	65098384	65098384	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	65098384	65098384	C	T	SNP	CACHD1	ENST00000371073	human	ensembl	74_37	+1	known	silent	c.747	p.D249	0.840	pfscan_VWF_A	pfam_VWA_N,pfam_Cache_domain,pfscan_VWF_A	-	no_errors	CACHD1	HGNC	ENSG00000158966				56	0	0	51	8	13.5593
CAMTA1	0	genome.wustl.edu	37	1	7151399	7151399	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	7151399	7151399	C	T	SNP	CAMTA1	ENST00000303635	human	ensembl	74_37	+1	known	silent	c.270	p.H90	1.000	pfam_CG-1_dom	pfam_CG-1_dom,pfam_IPT,pfam_IQ_motif_EF-hand-BS,superfamily_Ig_E-set,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_IQ_motif_EF-hand-BS	-	no_errors	CAMTA1	HGNC	ENSG00000171735				46	0	0	33	6	15.3846
CLCA2	0	genome.wustl.edu	37	1	86900342	86900342	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	1	86900342	86900342	C	T	SNP	CLCA2	ENST00000370565	human	ensembl	74_37	+1	known	missense	c.886	p.L296F	0.916	tigrfam_CaCC_prot	pfam_Cl_channel_Ca,pfam_DUF1973,pfam_VWF_A,smart_VWF_A,pfscan_VWF_A,tigrfam_CaCC_prot	-	no_errors	CLCA2	HGNC	ENSG00000137975				103	0	0	97	8	7.61905
SLC39A12	0	genome.wustl.edu	37	10	18242355	18242355	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	18242355	18242355	C	G	SNP	SLC39A12	ENST00000377369	human	ensembl	74_37	+1	known	silent	c.150	p.L50	0.954	NULL	pfam_ZIP	-	no_errors	SLC39A12	HGNC	ENSG00000148482				82	0	0	73	5	6.41026
SLC39A12	0	genome.wustl.edu	37	10	18250710	18250710	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	18250710	18250710	A	C	SNP	SLC39A12	ENST00000377369	human	ensembl	74_37	+1	known	missense	c.462	p.E154D	1.000	NULL	pfam_ZIP	-	no_errors	SLC39A12	HGNC	ENSG00000148482				65	0	0	50	14	21.875
NET1	0	genome.wustl.edu	37	10	5496479	5496479	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	5496479	5496479	G	T	SNP	NET1	ENST00000355029	human	ensembl	74_37	+1	known	missense	c.1020	p.E340D	0.985	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,pfscan_DH-domain	pfam_DH-domain,pfam_Pleckstrin_homology,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	NET1	HGNC	ENSG00000173848				53	0	0	44	4	8.33333
PCDH15	0	genome.wustl.edu	37	10	55566868	55566868	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	55566868	55566868	T	G	SNP	PCDH15	ENST00000414778	human	ensembl	74_37	-1	known	missense	c.4517	p.K1506T	1.000	NULL	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275				27	0	0	18	4	18.1818
PCDH15	0	genome.wustl.edu	37	10	55973754	55973754	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	55973754	55973754	A	G	SNP	PCDH15	ENST00000320301	human	ensembl	74_37	-1	known	missense	c.1040	p.L347P	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275				43	0	0	55	7	11.2903
BICC1	0	genome.wustl.edu	37	10	60560796	60560796	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	60560796	60560796	T	G	SNP	BICC1	ENST00000373886	human	ensembl	74_37	+1	known	missense	c.2005	p.S669A	1.000	NULL	pfam_KH_dom_type_1,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_KH_dom,smart_SAM,pfscan_SAM,pfscan_KH_dom_type_1	-	no_errors	BICC1	HGNC	ENSG00000122870				57	0	0	26	9	25.7143
BICC1	0	genome.wustl.edu	37	10	60566912	60566912	+	Silent	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	10	60566912	60566912	T	A	SNP	BICC1	ENST00000373886	human	ensembl	74_37	+1	known	silent	c.2370	p.T790	0.332	NULL	pfam_KH_dom_type_1,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_KH_dom,smart_SAM,pfscan_SAM,pfscan_KH_dom_type_1	-	no_errors	BICC1	HGNC	ENSG00000122870				118	0	0	64	7	9.85915
CNTN5	0	genome.wustl.edu	37	11	100179143	100179143	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	100179143	100179143	G	C	SNP	CNTN5	ENST00000279463	human	ensembl	74_37	+1	known	missense	c.2673	p.E891D	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	CNTN5	HGNC	ENSG00000149972				30	0	0	49	3	5.76923
SLC17A6	0	genome.wustl.edu	37	11	22363082	22363082	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	22363082	22363082	A	C	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.95	p.E32A	1.000	superfamily_MFS_dom_general_subst_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664				119	0	0	99	7	6.60377
BDNF	0	genome.wustl.edu	37	11	27679558	27679558	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	27679558	27679558	T	C	SNP	BDNF	ENST00000438929	human	ensembl	74_37	-1	known	missense	c.800	p.K267R	1.000	pfam_Nerve_growth_factor-rel,smart_Nerve_growth_factor-rel,pfscan_Nerve_growth_factor-rel,prints_Nerve_growth_factor-rel	pfam_Nerve_growth_factor-rel,smart_Nerve_growth_factor-rel,pfscan_Nerve_growth_factor-rel,prints_Brain-der_neurotrophic_factor,prints_Nerve_growth_factor-rel	-	no_errors	BDNF	HGNC	ENSG00000176697				225	0	0	183	17	8.5
OR5D16	0	genome.wustl.edu	37	11	55606311	55606311	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	55606311	55606311	C	T	SNP	OR5D16	ENST00000378396	human	ensembl	74_37	+1	known	silent	c.84	p.P28	0.048	prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5D16	HGNC	ENSG00000205029				124	0	0	117	12	9.30233
OR8H3	0	genome.wustl.edu	37	11	55890034	55890034	+	Silent	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	55890034	55890034	T	C	SNP	OR8H3	ENST00000313472	human	ensembl	74_37	+1	known	silent	c.186	p.F62	0.934	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8H3	HGNC	ENSG00000181761				421	0	0	305	67	18.0108
DAGLA	0	genome.wustl.edu	37	11	61487655	61487655	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	61487655	61487655	C	T	SNP	DAGLA	ENST00000257215	human	ensembl	74_37	+1	known	missense	c.28	p.R10C	1.000	NULL	pfam_Lipase_3	-	no_errors	DAGLA	HGNC	ENSG00000134780				100	0	0	88	6	6.38298
TUT1	0	genome.wustl.edu	37	11	62356651	62356651	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	62356651	62356651	T	C	SNP	TUT1	ENST00000308436	human	ensembl	74_37	-1	known	missense	c.239	p.H80R	1.000	NULL	pfam_PAP_assoc,pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	TUT1	HGNC	ENSG00000149016				62	0	0	66	5	7.04225
CCKBR	0	genome.wustl.edu	37	11	6291982	6291982	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	6291982	6291982	G	A	SNP	CCKBR	ENST00000525462	human	ensembl	74_37	+1	known	missense	c.760	p.D254N	0.437	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Gastrin_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Gastrin_rcpt,prints_Cholcskin_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	CCKBR	HGNC	ENSG00000110148				83	0	0	46	15	24.5902
RTN3	0	genome.wustl.edu	37	11	63487821	63487821	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	63487821	63487821	C	T	SNP	RTN3	ENST00000377819	human	ensembl	74_37	+1	known	missense	c.1847	p.S616F	0.217	NULL	pfam_Reticulon,pfscan_Reticulon	-	no_errors	RTN3	HGNC	ENSG00000133318				99	0	0	113	6	5.04202
IGHMBP2	0	genome.wustl.edu	37	11	68675677	68675677	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	68675677	68675677	C	T	SNP	IGHMBP2	ENST00000255078	human	ensembl	74_37	+1	known	silent	c.321	p.T107	0.894	tigrfam_DNA_helicase_put	pfam_R3H_ss-bd,pfam_Znf_AN1,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_AAA+_ATPase,smart_R3H_ss-bd,smart_Znf_AN1,pfscan_Znf_AN1,pfscan_R3H_ss-bd,tigrfam_DNA_helicase_put	-	no_errors	IGHMBP2	HGNC	ENSG00000132740				139	0	0	127	43	25.2941
NUMA1	0	genome.wustl.edu	37	11	71726700	71726700	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	71726700	71726700	G	A	SNP	NUMA1	ENST00000393695	human	ensembl	74_37	-1	known	silent	c.1849	p.L617	0.805	NULL	superfamily_Prefoldin	-	no_errors	NUMA1	HGNC	ENSG00000137497				46	0	0	49	11	18.3333
CREBZF	0	genome.wustl.edu	37	11	85375742	85375742	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	11	85375742	85375742	C	T	SNP	CREBZF	ENST00000525639	human	ensembl	74_37	-1	known	missense	c.178	p.E60K	0.788	NULL	pfam_bZIP	-	no_errors	CREBZF	HGNC	ENSG00000137504				89	0	0	72	10	12.1951
NR1H4	0	genome.wustl.edu	37	12	100904824	100904824	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	100904824	100904824	G	A	SNP	NR1H4	ENST00000551379	human	ensembl	74_37	+1	known	silent	c.378	p.A126	0.000	prints_ThyrH_rcpt	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_ThyrH_rcpt	-	no_errors	NR1H4	HGNC	ENSG00000012504				112	0	0	99	9	8.33333
ACACB	0	genome.wustl.edu	37	12	109692128	109692128	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	109692128	109692128	G	A	SNP	ACACB	ENST00000338432	human	ensembl	74_37	+1	known	missense	c.6155	p.R2052K	1.000	pfam_Carboxyl_trans,pfscan_COA_CT_C	pfam_AcCoA_COase_cen,pfam_Carboxyl_trans,pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_CarbamoylP_synth_lsu_N,pfam_Biotin_COase_C,pfam_Biotin_lipoyl,superfamily_PreATP-grasp_dom,superfamily_Rudment_hybrid_motif,superfamily_Single_hybrid_motif,smart_Biotin_COase_C,pfscan_ATP-grasp,pfscan_Biotin_carboxylation_dom,pfscan_COA_CT_N,pfscan_COA_CT_C,pfscan_Biotin_lipoyl	-	no_errors	ACACB	HGNC	ENSG00000076555				211	0	0	156	22	12.3596
KSR2	0	genome.wustl.edu	37	12	117962864	117962864	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	117962864	117962864	A	T	SNP	KSR2	ENST00000339824	human	ensembl	74_37	-1	known	missense	c.2012	p.L671H	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	KSR2	HGNC	ENSG00000171435				55	0	0	32	5	13.5135
GRIN2B	0	genome.wustl.edu	37	12	13716489	13716489	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	13716489	13716489	G	C	SNP	GRIN2B	ENST00000609686	human	ensembl	74_37	-1	known	missense	c.3683	p.T1228R	0.019	pfam_NMDAR2_C	pfam_NMDAR2_C,pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN2B	HGNC	ENSG00000273079				87	0	0	74	4	5.12821
PDE3A	0	genome.wustl.edu	37	12	20801740	20801740	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	20801740	20801740	A	T	SNP	PDE3A	ENST00000359062	human	ensembl	74_37	+1	known	missense	c.2684	p.K895M	1.000	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	-	no_errors	PDE3A	HGNC	ENSG00000172572				113	0	0	73	8	9.87654
ANKRD33	0	genome.wustl.edu	37	12	52282975	52282975	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	52282975	52282975	A	G	SNP	ANKRD33	ENST00000340970	human	ensembl	74_37	+1	known	missense	c.116	p.Q39R	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKRD33	HGNC	ENSG00000167612				113	0	0	98	8	7.54717
KRT6B	0	genome.wustl.edu	37	12	52840977	52840977	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	52840977	52840977	G	A	SNP	KRT6B	ENST00000252252	human	ensembl	74_37	-1	known	silent	c.1692	p.H564	0.192	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT6B	HGNC	ENSG00000185479				105	0	0	74	13	14.9425
GLI1	0	genome.wustl.edu	37	12	57864192	57864192	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	12	57864192	57864192	C	T	SNP	GLI1	ENST00000228682	human	ensembl	74_37	+1	known	missense	c.1669	p.R557C	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLI1	HGNC	ENSG00000111087				131	0	0	97	17	14.9123
FGF14	0	genome.wustl.edu	37	13	102379052	102379052	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	102379052	102379052	A	G	SNP	FGF14	ENST00000376131	human	ensembl	74_37	-1	known	silent	c.532	p.L178	1.000	pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam	pfam_Fibroblast_GF_fam,superfamily_Cytokine_IL1-like,smart_Fibroblast_GF_fam,prints_Fibroblast_GF_fam,prints_IL-1_fam/FGF_fam	-	no_errors	FGF14	HGNC	ENSG00000102466				70	0	0	49	21	30
PARP4	0	genome.wustl.edu	37	13	25066627	25066627	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	25066627	25066627	G	C	SNP	PARP4	ENST00000381989	human	ensembl	74_37	-1	known	missense	c.985	p.P329A	0.996	superfamily_Poly(ADP-ribose)pol_reg_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	pfam_Poly(ADP-ribose)pol_cat_dom,pfam_VIT,pfam_VWF_A,pfam_BRCT_dom,superfamily_Poly(ADP-ribose)pol_reg_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_VIT,smart_VWF_A,pfscan_BRCT_dom,pfscan_VWF_A,pfscan_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	-	no_errors	PARP4	HGNC	ENSG00000102699				117	0	0	77	6	7.22892
CCNA1	0	genome.wustl.edu	37	13	37016441	37016441	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	37016441	37016441	A	G	SNP	CCNA1	ENST00000255465	human	ensembl	74_37	+1	known	missense	c.1346	p.K449R	1.000	pfam_Cyclin_C-dom,superfamily_Cyclin-like,pirsf_Cyclin_A/B/D/E	pfam_Cyclin_N,pfam_Cyclin_C-dom,superfamily_Cyclin-like,smart_Cyclin-like,pirsf_Cyclin_A/B/D/E	-	no_errors	CCNA1	HGNC	ENSG00000133101				75	0	0	38	11	22.449
RB1	0	genome.wustl.edu	37	13	48919318	48919318	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	48919318	48919318	C	G	SNP	RB1	ENST00000267163	human	ensembl	74_37	+1	known	silent	c.483	p.L161	0.995	pfam_RB_N	pfam_RB_C,pfam_RB_A,pfam_RB_B,pfam_RB_N,superfamily_Cyclin-like,smart_Cyclin-like	-	no_errors	RB1	HGNC	ENSG00000139687				81	0	0	54	10	15.625
RCBTB2	0	genome.wustl.edu	37	13	49084829	49084829	+	Nonsense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	49084829	49084829	G	A	SNP	RCBTB2	ENST00000430805	human	ensembl	74_37	-1	known	nonsense	c.877	p.Q293*	1.000	pfam_Reg_chr_condens,superfamily_RCC1/BLIP-II,pfscan_Reg_chr_condens,prints_Reg_chr_condens	pfam_Reg_chr_condens,pfam_BTB_POZ,superfamily_RCC1/BLIP-II,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,pfscan_BTB/POZ-like,pfscan_Reg_chr_condens,prints_Reg_chr_condens	-	no_errors	RCBTB2	HGNC	ENSG00000136161				82	0	0	68	4	5.55556
HS6ST3	0	genome.wustl.edu	37	13	97485087	97485087	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	13	97485087	97485087	T	C	SNP	HS6ST3	ENST00000376705	human	ensembl	74_37	+1	known	missense	c.1051	p.F351L	1.000	pfam_Sulfotransferase	pfam_Sulfotransferase,superfamily_P-loop_NTPase	-	no_errors	HS6ST3	HGNC	ENSG00000185352				96	0	0	57	8	12.3077
OR4Q3	0	genome.wustl.edu	37	14	20216395	20216395	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	20216395	20216395	A	C	SNP	OR4Q3	ENST00000331723	human	ensembl	74_37	+1	known	missense	c.809	p.K270T	0.580	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4Q3	HGNC	ENSG00000182652				168	0	0	107	20	15.748
OR4K5	0	genome.wustl.edu	37	14	20388990	20388990	+	Silent	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	20388990	20388990	T	A	SNP	OR4K5	ENST00000315915	human	ensembl	74_37	+1	known	silent	c.225	p.S75	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4K5	HGNC	ENSG00000176281				354	0	0	273	38	12.2186
NYNRIN	0	genome.wustl.edu	37	14	24885245	24885245	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	24885245	24885245	C	T	SNP	NYNRIN	ENST00000382554	human	ensembl	74_37	+1	known	silent	c.4290	p.T1430	1.000	superfamily_RNaseH-like_dom	pfam_RNase_Zc3h12,superfamily_RNaseH-like_dom,pfscan_Integrase_cat-core	-	no_errors	NYNRIN	HGNC	ENSG00000205978				117	0	0	90	7	7.21649
AKAP6	0	genome.wustl.edu	37	14	33291387	33291387	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	33291387	33291387	A	C	SNP	AKAP6	ENST00000280979	human	ensembl	74_37	+1	known	missense	c.4368	p.E1456D	1.000	NULL	smart_Spectrin/alpha-actinin	-	no_errors	AKAP6	HGNC	ENSG00000151320				35	0	0	30	7	18.9189
ZFYVE1	0	genome.wustl.edu	37	14	73464684	73464684	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	73464684	73464684	C	T	SNP	ZFYVE1	ENST00000553891	human	ensembl	74_37	-1	known	missense	c.823	p.D275N	1.000	superfamily_P-loop_NTPase,superfamily_Growth_fac_rcpt_N_dom	pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,superfamily_P-loop_NTPase,superfamily_Growth_fac_rcpt_N_dom,smart_Znf_FYVE,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE1	HGNC	ENSG00000165861				82	0	0	61	12	16.4384
FLRT2	0	genome.wustl.edu	37	14	86087886	86087886	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	86087886	86087886	A	G	SNP	FLRT2	ENST00000330753	human	ensembl	74_37	+1	known	missense	c.28	p.S10G	0.997	NULL	pfam_Leu-rich_rpt,pfam_Fibronectin_type3,pfam_LRR-contain_N,superfamily_Fibronectin_type3,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,pfscan_Fibronectin_type3	-	no_errors	FLRT2	HGNC	ENSG00000185070				100	0	0	62	19	23.4568
FLRT2	0	genome.wustl.edu	37	14	86088396	86088396	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	86088396	86088396	G	C	SNP	FLRT2	ENST00000330753	human	ensembl	74_37	+1	known	missense	c.538	p.V180L	0.849	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,pfam_Fibronectin_type3,pfam_LRR-contain_N,superfamily_Fibronectin_type3,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,pfscan_Fibronectin_type3	-	no_errors	FLRT2	HGNC	ENSG00000185070				63	0	0	58	14	19.4444
ATP10A	0	genome.wustl.edu	37	15	25924926	25924926	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	25924926	25924926	A	C	SNP	ATP10A	ENST00000356865	human	ensembl	74_37	-1	known	silent	c.4062	p.S1354	0.000	NULL	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP10A	HGNC	ENSG00000206190				115	1	0.862069	86	6	6.52174
ATP10A	0	genome.wustl.edu	37	15	25963457	25963457	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	25963457	25963457	C	T	SNP	ATP10A	ENST00000356865	human	ensembl	74_37	-1	known	missense	c.1453	p.G485S	0.712	superfamily_HAD-like_dom,tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP10A	HGNC	ENSG00000206190				32	0	0	29	4	12.1212
DUT	0	genome.wustl.edu	37	15	48633776	48633776	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	48633776	48633776	A	C	SNP	DUT	ENST00000331200	human	ensembl	74_37	+1	known	missense	c.696	p.E232D	1.000	pfam_dUTP_pyroPase,tigrfam_dUTP_pyroPase_sf	pfam_dUTP_pyroPase,tigrfam_dUTP_pyroPase_sf	-	no_errors	DUT	HGNC	ENSG00000128951				36	0	0	17	3	15
FAM214A	0	genome.wustl.edu	37	15	52901351	52901351	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	52901351	52901351	T	G	SNP	FAM214A	ENST00000261844	human	ensembl	74_37	-1	known	missense	c.1760	p.Q587P	0.440	NULL	NULL	-	no_errors	FAM214A	HGNC	ENSG00000047346				60	0	0	35	6	14.6341
BNC1	0	genome.wustl.edu	37	15	83935597	83935597	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	15	83935597	83935597	G	A	SNP	BNC1	ENST00000345382	human	ensembl	74_37	-1	known	silent	c.426	p.Y142	0.046	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	BNC1	HGNC	ENSG00000169594				108	0	0	70	8	10.2564
NOMO1	0	genome.wustl.edu	37	16	14968903	14968903	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	16	14968903	14968903	G	A	SNP	NOMO1	ENST00000287667	human	ensembl	74_37	+1	known	missense	c.2065	p.D689N	1.000	NULL	pfam_DUF2012,superfamily_CarboxyPept-like_regulatory,superfamily_Carb-bd-like_fold,superfamily_Collagen-bd_Cna_B-typ_dom	-	no_errors	NOMO1	HGNC	ENSG00000103512				111	0	0	83	5	5.68182
HS3ST3B1	0	genome.wustl.edu	37	17	14248463	14248463	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	14248463	14248463	G	A	SNP	HS3ST3B1	ENST00000360954	human	ensembl	74_37	+1	known	missense	c.673	p.V225M	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST3B1	HGNC	ENSG00000125430				60	0	0	37	22	37.2881
KRT34	0	genome.wustl.edu	37	17	39535241	39535241	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	39535241	39535241	G	A	SNP	KRT34	ENST00000394001	human	ensembl	74_37	-1	known	missense	c.1190	p.T397M	0.864	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT34	HGNC	ENSG00000131737				178	0	0	117	17	12.6866
KRT16	0	genome.wustl.edu	37	17	39768514	39768514	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	39768514	39768514	C	T	SNP	KRT16	ENST00000301653	human	ensembl	74_37	-1	known	missense	c.427	p.A143T	0.000	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT16	HGNC	ENSG00000186832				204	0	0	147	9	5.76923
ITGB3	0	genome.wustl.edu	37	17	45368487	45368487	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	45368487	45368487	A	C	SNP	ITGB3	ENST00000571680	human	ensembl	74_37	+1	putative	silent	c.1293	p.G431	0.000	smart_Integrin_bsu_N	pfam_Integrin_bsu_N,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,prints_Integrin_bsu	-	no_errors	ITGB3	HGNC	ENSG00000259207				66	0	0	49	4	7.54717
TP53	0	genome.wustl.edu	37	17	7577121	7577121	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	7577121	7577121	G	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.817	p.R273C	0.830	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510				39	0	0	18	3	14.2857
TRAPPC8	0	genome.wustl.edu	37	18	29437875	29437875	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	29437875	29437875	T	C	SNP	TRAPPC8	ENST00000283351	human	ensembl	74_37	-1	known	missense	c.2816	p.N939S	1.000	NULL	NULL	-	no_errors	TRAPPC8	HGNC	ENSG00000153339				210	0	0	120	29	19.4631
EPB41L3	0	genome.wustl.edu	37	18	5394764	5394764	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	5394764	5394764	T	C	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.3182	p.K1061R	1.000	pirsf_Band_41_protein,pfam_Band_4.1_C	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397				106	0	0	65	10	13.3333
EPB41L3	0	genome.wustl.edu	37	18	5397201	5397201	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	18	5397201	5397201	C	A	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.2697	p.E899D	0.938	pirsf_Band_41_protein	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397				151	0	0	110	26	19.1176
COL5A3	0	genome.wustl.edu	37	19	10088308	10088308	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	10088308	10088308	C	T	SNP	COL5A3	ENST00000264828	human	ensembl	74_37	-1	known	missense	c.3088	p.E1030K	0.147	NULL	pfam_Collagen,pfam_Fib_collagen_C,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_Fib_collagen_C	-	no_errors	COL5A3	HGNC	ENSG00000080573				40	0	0	27	3	10
WDR83	0	genome.wustl.edu	37	19	12781077	12781077	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	12781077	12781077	G	A	SNP	WDR83	ENST00000242796	human	ensembl	74_37	+1	known	missense	c.308	p.R103H	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	WDR83	HGNC	ENSG00000123154				150	0	0	108	16	12.9032
MAP1S	0	genome.wustl.edu	37	19	17844187	17844187	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	17844187	17844187	G	A	SNP	MAP1S	ENST00000324096	human	ensembl	74_37	+1	known	missense	c.2974	p.V992I	0.971	NULL	NULL	-	no_errors	MAP1S	HGNC	ENSG00000130479				33	0	0	21	3	12.5
ZNF100	0	genome.wustl.edu	37	19	21926888	21926888	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	21926888	21926888	T	A	SNP	ZNF100	ENST00000358296	human	ensembl	74_37	-1	known	missense	c.253	p.I85F	0.073	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF100	HGNC	ENSG00000197020				136	0	0	73	12	14.1176
TSHZ3	0	genome.wustl.edu	37	19	31767597	31767597	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	31767597	31767597	C	A	SNP	TSHZ3	ENST00000240587	human	ensembl	74_37	-1	known	missense	c.3102	p.E1034D	0.998	NULL	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	TSHZ3	HGNC	ENSG00000121297				49	0	0	32	3	8.57143
NPHS1	0	genome.wustl.edu	37	19	36317473	36317473	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	36317473	36317473	G	T	SNP	NPHS1	ENST00000378910	human	ensembl	74_37	-1	known	missense	c.3669	p.D1223E	0.130	NULL	pfam_CD80_C2-set,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	NPHS1	HGNC	ENSG00000161270				70	0	0	43	10	18.8679
EEF2	0	genome.wustl.edu	37	19	3977945	3977945	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	3977945	3977945	G	A	SNP	EEF2	ENST00000309311	human	ensembl	74_37	-1	known	missense	c.1939	p.R647C	1.000	pfam_Transl_elong_EFG/EF2_IV,superfamily_Ribosomal_S5_D2-typ_fold,smart_Transl_elong_EFG/EF2_IV	pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFG/EF2_IV,pfam_EFG_V,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_Transl_B-barrel,superfamily_EFG_III-V,smart_Transl_elong_EFG/EF2_IV,smart_EFG_V,prints_EF_GTP-bd_dom,tigrfam_Small_GTP-bd_dom	-	no_errors	EEF2	HGNC	ENSG00000167658				62	0	0	54	11	16.9231
SYMPK	0	genome.wustl.edu	37	19	46347310	46347310	+	Silent	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	46347310	46347310	G	T	SNP	SYMPK	ENST00000245934	human	ensembl	74_37	-1	known	silent	c.825	p.I275	1.000	pfam_DUF3453,superfamily_ARM-type_fold	pfam_DUF3453,pfam_Symplekin_C,superfamily_ARM-type_fold	-	no_errors	SYMPK	HGNC	ENSG00000125755				108	0	0	41	7	14.5833
IL4I1	0	genome.wustl.edu	37	19	50397635	50397635	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	50397635	50397635	T	A	SNP	IL4I1	ENST00000341114	human	ensembl	74_37	-1	known	nonsense	c.523	p.K175*	0.591	pfam_Amino_oxidase	pfam_Amino_oxidase,pfam_FAD-dep_OxRdtase,pfam_CHP00275_HI0933-like,pfam_FAD_bind_dom,pfam_Pyr_OxRdtase_NAD-bd_dom,pfam_AlaDH/PNT_NAD(H)-bd,pfam_mOase_FAD-bd,prints_Flavin_amine_oxidase	-	no_errors	IL4I1	HGNC	ENSG00000104951				95	0	0	79	6	7.05882
NLRP9	0	genome.wustl.edu	37	19	56241343	56241343	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	56241343	56241343	G	A	SNP	NLRP9	ENST00000332836	human	ensembl	74_37	-1	known	silent	c.1848	p.L616	0.000	NULL	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP9	HGNC	ENSG00000185792				98	0	0	67	11	14.1026
ZIM2	0	genome.wustl.edu	37	19	57286620	57286620	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	19	57286620	57286620	T	G	SNP	ZIM2	ENST00000221722	human	ensembl	74_37	-1	known	missense	c.1020	p.Q340H	0.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Krueppel-associated_box,pfam_Znf_C2H2,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZIM2	HGNC	ENSG00000269699				84	0	0	62	10	13.8889
LRP1B	0	genome.wustl.edu	37	2	141259339	141259339	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	141259339	141259339	T	A	SNP	LRP1B	ENST00000389484	human	ensembl	74_37	-1	known	nonsense	c.8767	p.R2923*	1.000	pfam_LDrepeatLR_classA_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EG-like_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1B	HGNC	ENSG00000168702				65	0	0	44	8	15.3846
NBAS	0	genome.wustl.edu	37	2	15307290	15307290	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	15307290	15307290	T	G	SNP	NBAS	ENST00000281513	human	ensembl	74_37	-1	known	missense	c.6998	p.H2333P	0.998	NULL	pfam_Sec39,superfamily_Quino_amine_DH_bsu	-	no_errors	NBAS	HGNC	ENSG00000151779				57	0	0	42	5	10.6383
TTN	0	genome.wustl.edu	37	2	179416419	179416419	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	179416419	179416419	T	C	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.83504	p.N27835S	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657				58	0	0	48	5	9.43396
MYT1L	0	genome.wustl.edu	37	2	1812914	1812914	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	1812914	1812914	A	C	SNP	MYT1L	ENST00000399161	human	ensembl	74_37	-1	known	missense	c.3106	p.S1036A	0.993	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1L	HGNC	ENSG00000186487				139	0	0	92	10	9.80392
HSPD1	0	genome.wustl.edu	37	2	198351917	198351917	+	Silent	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	198351917	198351917	C	G	SNP	HSPD1	ENST00000345042	human	ensembl	74_37	-1	known	silent	c.1575	p.V525	1.000	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,tigrfam_Chaprnin_Cpn60	pfam_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,superfamily_Cpn60/TCP-1,prints_Chaprnin_Cpn60,prints_Chaperone_TCP-1,tigrfam_Chaprnin_Cpn60	-	no_errors	HSPD1	HGNC	ENSG00000144381				44	0	0	23	4	14.8148
APOB	0	genome.wustl.edu	37	2	21249694	21249694	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	21249694	21249694	T	A	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	missense	c.2210	p.H737L	1.000	pfam_Vitellinogen_open_b-sht,superfamily_Lipid_transp_b-sht_shell	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674				112	0	0	72	13	15.2941
MOGAT1	0	genome.wustl.edu	37	2	223559200	223559200	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	223559200	223559200	T	C	SNP	MOGAT1	ENST00000446656	human	ensembl	74_37	+1	known	missense	c.598	p.F200L	0.002	pfam_DAGAT	pfam_DAGAT	-	no_errors	MOGAT1	HGNC	ENSG00000124003				54	0	0	26	6	18.75
FAM98A	0	genome.wustl.edu	37	2	33810020	33810020	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	33810020	33810020	A	G	SNP	FAM98A	ENST00000238823	human	ensembl	74_37	-1	known	silent	c.1380	p.G460	0.997	NULL	pfam_Uncharacterised_FAM98	-	no_errors	FAM98A	HGNC	ENSG00000119812				159	0	0	102	8	7.27273
NRXN1	0	genome.wustl.edu	37	2	51254923	51254923	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	51254923	51254923	G	A	SNP	NRXN1	ENST00000402717	human	ensembl	74_37	-1	known	silent	c.489	p.R163	0.650	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_EG-like_dom,smart_Neurexin-like,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	NRXN1	HGNC	ENSG00000179915				30	0	0	24	3	11.1111
LRRTM4	0	genome.wustl.edu	37	2	77746793	77746793	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	77746793	77746793	A	C	SNP	LRRTM4	ENST00000409911	human	ensembl	74_37	-1	known	missense	c.205	p.L69V	0.052	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRTM4	HGNC	ENSG00000176204				103	0	0	67	10	12.987
CTNNA2	0	genome.wustl.edu	37	2	80085262	80085262	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	80085262	80085262	C	A	SNP	CTNNA2	ENST00000361291	human	ensembl	74_37	+1	known	missense	c.524	p.A175E	1.000	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA2	HGNC	ENSG00000066032				89	0	0	50	12	19.3548
CTNNA2	0	genome.wustl.edu	37	2	80646693	80646693	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	80646693	80646693	A	G	SNP	CTNNA2	ENST00000361291	human	ensembl	74_37	+1	known	silent	c.1359	p.Q453	0.997	pfam_Vinculin/catenin,superfamily_Vinculin/catenin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA2	HGNC	ENSG00000066032				79	0	0	50	4	7.40741
EIF2AK3	0	genome.wustl.edu	37	2	88890104	88890104	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	88890104	88890104	G	C	SNP	EIF2AK3	ENST00000303236	human	ensembl	74_37	-1	known	missense	c.1022	p.S341C	1.000	superfamily_Quinonprotein_ADH-like_supfam	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	EIF2AK3	HGNC	ENSG00000172071				38	0	0	28	3	9.67742
EIF2AK3	0	genome.wustl.edu	37	2	88890409	88890409	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	2	88890409	88890409	A	C	SNP	EIF2AK3	ENST00000303236	human	ensembl	74_37	-1	known	missense	c.929	p.I310R	1.000	superfamily_Quinonprotein_ADH-like_supfam	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Quinonprotein_ADH-like_supfam,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	EIF2AK3	HGNC	ENSG00000172071				144	0	0	113	7	5.83333
ESF1	0	genome.wustl.edu	37	20	13740371	13740371	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	13740371	13740371	T	G	SNP	ESF1	ENST00000202816	human	ensembl	74_37	-1	known	missense	c.1796	p.N599T	1.000	NULL	pfam_NUC153	-	no_errors	ESF1	HGNC	ENSG00000089048				28	0	0	16	4	20
CST5	0	genome.wustl.edu	37	20	23856831	23856831	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	23856831	23856831	T	G	SNP	CST5	ENST00000304710	human	ensembl	74_37	-1	known	missense	c.423	p.K141N	0.000	NULL	pfam_Prot_inh_cystat,smart_Prot_inh_cystat	-	no_errors	CST5	HGNC	ENSG00000170367				89	0	0	44	26	37.1429
DEFB115	0	genome.wustl.edu	37	20	29845528	29845528	+	Missense_Mutation	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	29845528	29845528	T	G	SNP	DEFB115	ENST00000400552	human	ensembl	74_37	+1	known	missense	c.62	p.V21G	0.174	NULL	NULL	-	no_errors	DEFB115	HGNC	ENSG00000215547				93	0	0	54	7	11.4754
PCIF1	0	genome.wustl.edu	37	20	44569764	44569764	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	44569764	44569764	G	A	SNP	PCIF1	ENST00000372409	human	ensembl	74_37	+1	known	silent	c.591	p.P197	0.100	NULL	pfam_PCIF1_WW,pfam_WW_dom,superfamily_WW_dom,smart_WW_dom,pfscan_WW_dom	-	no_errors	PCIF1	HGNC	ENSG00000100982				57	0	0	56	4	6.66667
PHACTR3	0	genome.wustl.edu	37	20	58348371	58348371	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	58348371	58348371	T	A	SNP	PHACTR3	ENST00000371015	human	ensembl	74_37	+1	known	missense	c.789	p.S263R	0.000	NULL	pfam_RPEL_repeat,smart_RPEL_repeat,pfscan_RPEL_repeat	-	no_errors	PHACTR3	HGNC	ENSG00000087495				137	1	0.724638	107	11	9.32203
ARFGAP1	0	genome.wustl.edu	37	20	61918947	61918947	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	61918947	61918947	G	A	SNP	ARFGAP1	ENST00000353546	human	ensembl	74_37	+1	known	missense	c.967	p.G323S	0.983	NULL	pfam_ArfGAP,smart_ArfGAP,pfscan_ArfGAP,prints_ArfGAP	-	no_errors	ARFGAP1	HGNC	ENSG00000101199				48	0	0	33	3	8.33333
SRMS	0	genome.wustl.edu	37	20	62178476	62178476	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	20	62178476	62178476	G	A	SNP	SRMS	ENST00000217188	human	ensembl	74_37	-1	known	missense	c.341	p.T114M	0.001	superfamily_SH3_domain	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH2,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_SH2,pfscan_SH3_domain,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH2	-	no_errors	SRMS	HGNC	ENSG00000125508				82	0	0	68	5	6.84932
BAGE2	0	genome.wustl.edu	37	21	11098863	11098863	+	RNA	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	21	11098863	11098863	A	G	SNP	BAGE2	ENST00000470054	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.043	-	-	-	no_errors	BAGE2	HGNC	ENSG00000187172				40	0	0	23	3	11.5385
MFNG	0	genome.wustl.edu	37	22	37876306	37876306	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	22	37876306	37876306	C	T	SNP	MFNG	ENST00000438891	human	ensembl	74_37	-1	known	missense	c.287	p.R96Q	0.002	NULL	pfam_Fringe-like	-	no_errors	MFNG	HGNC	ENSG00000100060				57	0	0	43	6	12.2449
TTLL12	0	genome.wustl.edu	37	22	43570378	43570378	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	22	43570378	43570378	G	A	SNP	TTLL12	ENST00000216129	human	ensembl	74_37	-1	known	silent	c.1066	p.L356	1.000	pfam_TTL/TTLL_fam	pfam_TTL/TTLL_fam	-	no_errors	TTLL12	HGNC	ENSG00000100304				73	0	0	49	8	14.0351
MED12L	0	genome.wustl.edu	37	3	150883667	150883667	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	150883667	150883667	A	C	SNP	MED12L	ENST00000474524	human	ensembl	74_37	+1	known	missense	c.1392	p.E464D	1.000	pfam_Mediator_Med12_LCEWAV	pfam_Mediator_Med12_LCEWAV,pfam_Mediator_Med12,pfam_Mediator_Med12_catenin-bd	-	no_errors	MED12L	HGNC	ENSG00000144893				142	0	0	121	8	6.20155
VEPH1	0	genome.wustl.edu	37	3	156983365	156983365	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	156983365	156983365	G	A	SNP	VEPH1	ENST00000362010	human	ensembl	74_37	-1	known	missense	c.2215	p.R739C	1.000	pfam_Pleckstrin_homology,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Pleckstrin_homology,superfamily_ARM-type_fold,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	-	no_errors	VEPH1	HGNC	ENSG00000197415				69	0	0	55	6	9.83607
SI	0	genome.wustl.edu	37	3	164709237	164709237	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	164709237	164709237	A	C	SNP	SI	ENST00000264382	human	ensembl	74_37	-1	known	missense	c.5012	p.F1671C	0.000	pfam_Glyco_hydro_31	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	SI	HGNC	ENSG00000090402				48	0	0	39	3	7.14286
SI	0	genome.wustl.edu	37	3	164735779	164735779	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	164735779	164735779	A	G	SNP	SI	ENST00000264382	human	ensembl	74_37	-1	known	silent	c.3499	p.L1167	0.691	superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	SI	HGNC	ENSG00000090402				75	0	0	54	6	10
MB21D2	0	genome.wustl.edu	37	3	192517008	192517008	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	192517008	192517008	T	C	SNP	MB21D2	ENST00000392452	human	ensembl	74_37	-1	known	missense	c.643	p.K215E	1.000	NULL	pfam_Mab-21_dom	-	no_errors	MB21D2	HGNC	ENSG00000180611				90	0	0	78	6	7.14286
PIGZ	0	genome.wustl.edu	37	3	196674046	196674046	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	196674046	196674046	C	T	SNP	PIGZ	ENST00000412723	human	ensembl	74_37	-1	known	silent	c.1722	p.E574	0.997	NULL	pfam_GPI_mannosylTrfase	-	no_errors	PIGZ	HGNC	ENSG00000119227				78	0	0	74	4	5.12821
SLC4A7	0	genome.wustl.edu	37	3	27472839	27472839	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	27472839	27472839	G	A	SNP	SLC4A7	ENST00000454389	human	ensembl	74_37	-1	known	missense	c.1100	p.A367V	0.114	pfam_Band3_cytoplasmic_dom	pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,tigrfam_HCO3_transpt_euk	-	no_errors	SLC4A7	HGNC	ENSG00000033867				163	1	0.609756	104	11	9.56522
EPHA6	0	genome.wustl.edu	37	3	97356863	97356863	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	3	97356863	97356863	A	C	SNP	EPHA6	ENST00000389672	human	ensembl	74_37	+1	known	missense	c.2721	p.K907N	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	EPHA6	HGNC	ENSG00000080224				65	0	0	49	5	9.25926
KIAA1109	0	genome.wustl.edu	37	4	123130419	123130419	+	Missense_Mutation	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	123130419	123130419	A	C	SNP	KIAA1109	ENST00000264501	human	ensembl	74_37	+1	known	missense	c.1858	p.T620P	0.020	NULL	pfam_Fragile_site-assoc_C	-	no_errors	KIAA1109	HGNC	ENSG00000138688				67	0	0	24	4	14.2857
FAT4	0	genome.wustl.edu	37	4	126372685	126372685	+	Missense_Mutation	SNP	A	A	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	126372685	126372685	A	T	SNP	FAT4	ENST00000394329	human	ensembl	74_37	+1	known	missense	c.10514	p.D3505V	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT4	HGNC	ENSG00000196159				151	0	0	85	18	17.4757
SLC10A6	0	genome.wustl.edu	37	4	87769921	87769921	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	4	87769921	87769921	G	A	SNP	SLC10A6	ENST00000273905	human	ensembl	74_37	-1	known	silent	c.348	p.T116	1.000	pfam_BilAc/Na_symport,tigrfam_Bil_ac_transpt	pfam_BilAc/Na_symport,tigrfam_Bil_ac_transpt	-	no_errors	SLC10A6	HGNC	ENSG00000145283				114	0	0	96	17	15.0442
CAMK4	0	genome.wustl.edu	37	5	110679802	110679802	+	Splice_Site	SNP	T	T	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	110679802	110679802	T	G	SNP	CAMK4	ENST00000282356	human	ensembl	74_37	+1	known	splice_site	c.240+2	e2+2	1.000	-	-	-	no_errors	CAMK4	HGNC	ENSG00000152495				97	0	0	51	4	7.27273
SEMA6A	0	genome.wustl.edu	37	5	115815859	115815859	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	115815859	115815859	G	A	SNP	SEMA6A	ENST00000257414	human	ensembl	74_37	-1	known	silent	c.1209	p.P403	0.613	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom	-	no_errors	SEMA6A	HGNC	ENSG00000092421				84	0	0	45	8	15.0943
FAM71B	0	genome.wustl.edu	37	5	156592996	156592996	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	156592996	156592996	C	A	SNP	FAM71B	ENST00000302938	human	ensembl	74_37	-1	known	missense	c.184	p.D62Y	0.989	NULL	pfam_DUF3699	-	no_errors	FAM71B	HGNC	ENSG00000170613				115	0	0	74	14	15.9091
SOX30	0	genome.wustl.edu	37	5	157065338	157065338	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	5	157065338	157065338	G	C	SNP	SOX30	ENST00000265007	human	ensembl	74_37	-1	known	missense	c.1780	p.P594A	0.981	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	SOX30	HGNC	ENSG00000039600				59	0	0	37	3	7.5
SIM1	0	genome.wustl.edu	37	6	100911257	100911257	+	Missense_Mutation	SNP	G	G	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	100911257	100911257	G	C	SNP	SIM1	ENST00000262901	human	ensembl	74_37	-1	known	missense	c.88	p.P30A	1.000	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	pfam_SIM_C,pfam_PAS_fold_3,pfam_PAS_fold,pfam_bHLH_dom,superfamily_PAS,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,smart_PAC,pfscan_PAS,pfscan_bHLH_dom	-	no_errors	SIM1	HGNC	ENSG00000112246				127	0	0	90	5	5.26316
IFNGR1	0	genome.wustl.edu	37	6	137525557	137525557	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	137525557	137525557	T	C	SNP	IFNGR1	ENST00000367739	human	ensembl	74_37	-1	known	missense	c.458	p.N153S	0.034	pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3	pfam_Interferon_gamma_pox/mammal,pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3,prints_Interferon_gamma_rcpt_asu	-	no_errors	IFNGR1	HGNC	ENSG00000027697				95	0	0	68	15	18.0723
ESR1	0	genome.wustl.edu	37	6	152419948	152419948	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	152419948	152419948	C	T	SNP	ESR1	ENST00000206249	human	ensembl	74_37	+1	known	silent	c.1635	p.D545	0.398	superfamily_Nucl_hormone_rcpt_ligand-bd	pfam_Oestr_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Oestr_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	ESR1	HGNC	ENSG00000091831				63	0	0	32	6	15.7895
PARK2	0	genome.wustl.edu	37	6	162683735	162683735	+	Silent	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	162683735	162683735	T	C	SNP	PARK2	ENST00000366898	human	ensembl	74_37	-1	known	silent	c.234	p.Q78	0.000	pirsf_Parkin	pfam_Ubiquitin_dom,pfam_Znf_C6HC,pfam_Rad60/SUMO_like,smart_Ubiquitin_dom,smart_Znf_C6HC,pirsf_Parkin,pfscan_Ubiquitin_supergroup,prints_Parkin,prints_Ubiquitin	-	no_errors	PARK2	HGNC	ENSG00000185345				98	0	0	74	4	5.12821
ATXN1	0	genome.wustl.edu	37	6	16326661	16326661	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	16326661	16326661	G	A	SNP	ATXN1	ENST00000244769	human	ensembl	74_37	-1	known	silent	c.1881	p.A627	0.574	pfam_Ataxin-1_HBP1,superfamily_Ataxin-1_HBP1,smart_Ataxin_AXH_dom,pfscan_Ataxin-1_HBP1	pfam_Ataxin-1_HBP1,pfam_Capicua_tscrpt_rep_mod,superfamily_Ataxin-1_HBP1,smart_Ataxin_AXH_dom,pfscan_Ataxin-1_HBP1	-	no_errors	ATXN1	HGNC	ENSG00000124788				112	0	0	52	10	16.129
LOC101929006	0	genome.wustl.edu	37	6	29231769	29231769	+	RNA	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	29231769	29231769	A	C	SNP	LOC101929006	ENST00000441381	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.021	-	-	-	no_errors	XXbac-BPG308J9.3	Clone_based_vega_gene	ENSG00000232505				106	0	0	86	10	10.4167
MOG	0	genome.wustl.edu	37	6	29627404	29627404	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	29627404	29627404	T	A	SNP	MOG	ENST00000376898	human	ensembl	74_37	+1	known	missense	c.397	p.S133T	0.907	pirsf_Myelin-oligodendrocyte_glycop,pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	pirsf_Myelin-oligodendrocyte_glycop,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	MOG	HGNC	ENSG00000204655				43	0	0	38	3	7.31707
TRIM40	0	genome.wustl.edu	37	6	30114834	30114834	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	30114834	30114834	G	A	SNP	TRIM40	ENST00000376724	human	ensembl	74_37	+1	known	missense	c.514	p.G172S	0.007	NULL	pfam_Znf_C3HC4_RING-type,superfamily_tRNA-bd_arm,smart_Znf_RING,pfscan_Znf_B-box,pfscan_Znf_RING	-	no_errors	TRIM40	HGNC	ENSG00000204614				37	0	0	29	5	14.7059
ZBTB9	0	genome.wustl.edu	37	6	33423797	33423797	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	33423797	33423797	A	G	SNP	ZBTB9	ENST00000395064	human	ensembl	74_37	+1	known	missense	c.920	p.K307R	0.909	NULL	pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB9	HGNC	ENSG00000213588				122	0	0	95	7	6.86275
GSTA3	0	genome.wustl.edu	37	6	52761671	52761671	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	52761671	52761671	C	T	SNP	GSTA3	ENST00000211122	human	ensembl	74_37	-1	known	missense	c.602	p.G201D	1.000	superfamily_Glutathione-S-Trfase_C-like,prints_GST_alpha	pfam_Glutathione_S-Trfase_N,pfam_GST_C,superfamily_Glutathione-S-Trfase_C-like,superfamily_Thioredoxin-like_fold,prints_GST_alpha	-	no_errors	GSTA3	HGNC	ENSG00000174156				126	0	0	73	14	16.092
EPHB6	0	genome.wustl.edu	37	7	142567599	142567599	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	142567599	142567599	C	T	SNP	EPHB6	ENST00000392957	human	ensembl	74_37	+1	known	silent	c.2487	p.A829	0.989	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_2,pfam_SAM_type1,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHB6	HGNC	ENSG00000106123				56	0	0	27	7	20.5882
MAD1L1	0	genome.wustl.edu	37	7	2054206	2054206	+	Missense_Mutation	SNP	C	C	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	2054206	2054206	C	A	SNP	MAD1L1	ENST00000265854	human	ensembl	74_37	-1	known	missense	c.1290	p.Q430H	1.000	pfam_Mad1	pfam_Mad1	-	no_errors	MAD1L1	HGNC	ENSG00000002822				45	0	0	41	4	8.88889
DNAH11	0	genome.wustl.edu	37	7	21599226	21599226	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	21599226	21599226	C	T	SNP	DNAH11	ENST00000328843	human	ensembl	74_37	+1	known	missense	c.698	p.P233L	0.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH11	HGNC	ENSG00000105877				29	0	0	22	3	12
DNAH11	0	genome.wustl.edu	37	7	21784185	21784185	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	21784185	21784185	A	C	SNP	DNAH11	ENST00000328843	human	ensembl	74_37	+1	known	silent	c.8305	p.R2769	0.972	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH11	HGNC	ENSG00000105877				97	0	0	48	9	15.7895
ACTB	0	genome.wustl.edu	37	7	5568045	5568045	+	Silent	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	7	5568045	5568045	G	A	SNP	ACTB	ENST00000331789	human	ensembl	74_37	-1	known	silent	c.669	p.F223	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTB	HGNC	ENSG00000075624				116	1	0.854701	86	11	11.3402
RP1L1	0	genome.wustl.edu	37	8	10466100	10466100	+	Silent	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	10466100	10466100	C	T	SNP	RP1L1	ENST00000382483	human	ensembl	74_37	-1	known	silent	c.5508	p.E1836	0.004	NULL	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	-	no_errors	RP1L1	HGNC	ENSG00000183638				357	0	0	218	24	9.91736
LRP12	0	genome.wustl.edu	37	8	105502952	105502952	+	Silent	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	105502952	105502952	T	C	SNP	LRP12	ENST00000424843	human	ensembl	74_37	-1	known	silent	c.2472	p.E824	0.977	NULL	pfam_CUB_dom,pfam_LDrepeatLR_classA_rpt,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_LDrepeatLR_classA_rpt,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP12	HGNC	ENSG00000147650				103	0	0	59	6	9.23077
CSMD3	0	genome.wustl.edu	37	8	113871376	113871376	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	113871376	113871376	T	A	SNP	CSMD3	ENST00000297405	human	ensembl	74_37	-1	known	nonsense	c.1753	p.K585*	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD3	HGNC	ENSG00000164796				79	0	0	65	5	7.14286
FAM86B1	0	genome.wustl.edu	37	8	12042867	12042867	+	Missense_Mutation	SNP	G	G	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	12042867	12042867	G	T	SNP	FAM86B1	ENST00000321602	human	ensembl	74_37	-1	known	missense	c.226	p.P76T	0.000	NULL	NULL	-	no_errors	FAM86B1	HGNC	ENSG00000186523				207	1	0.480769	156	9	5.45455
UNC5D	0	genome.wustl.edu	37	8	35583918	35583918	+	Missense_Mutation	SNP	T	T	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	35583918	35583918	T	A	SNP	UNC5D	ENST00000404895	human	ensembl	74_37	+1	known	missense	c.1552	p.F518I	0.996	NULL	pfam_ZU5,pfam_Ig_I-set,pfam_Thrombospondin_1_rpt,pfam_Death_domain,pfam_Immunoglobulin,superfamily_DEATH-like_dom,superfamily_Thrombospondin_1_rpt,smart_Ig_sub,smart_Ig_sub2,smart_Thrombospondin_1_rpt,smart_ZU5,smart_Death_domain,pfscan_Thrombospondin_1_rpt,pfscan_ZU5,pfscan_Ig-like_dom	-	no_errors	UNC5D	HGNC	ENSG00000156687				120	0	0	61	16	20.7792
ANK1	0	genome.wustl.edu	37	8	41526051	41526051	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	8	41526051	41526051	C	T	SNP	ANK1	ENST00000396942	human	ensembl	74_37	-1	known	missense	c.5128	p.V1710I	0.005	NULL	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK1	HGNC	ENSG00000029534				66	0	0	42	17	28.8136
ELAVL2	0	genome.wustl.edu	37	9	23762204	23762204	+	Missense_Mutation	SNP	G	G	A			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	9	23762204	23762204	G	A	SNP	ELAVL2	ENST00000380117	human	ensembl	74_37	-1	known	missense	c.29	p.T10I	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,prints_Hud_Sxl_RNA,tigrfam_ELAD_HUD_SF	-	no_errors	ELAVL2	HGNC	ENSG00000107105				267	0	0	136	34	20
IRS4	0	genome.wustl.edu	37	X	107977167	107977167	+	Missense_Mutation	SNP	T	T	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	107977167	107977167	T	C	SNP	IRS4	ENST00000372129	human	ensembl	74_37	-1	known	missense	c.2408	p.K803R	1.000	NULL	pfam_Insln_rcpt_S1,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1,prints_Insln_rcpt_S1	-	no_errors	IRS4	HGNC	ENSG00000133124				121	0	0	78	36	31.5789
MAGEC3	0	genome.wustl.edu	37	X	140969448	140969448	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	140969448	140969448	A	G	SNP	MAGEC3	ENST00000298296	human	ensembl	74_37	+1	known	missense	c.775	p.T259A	0.021	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC3	HGNC	ENSG00000165509				119	0	0	54	25	31.6456
MAGEC1	0	genome.wustl.edu	37	X	140993285	140993285	+	Missense_Mutation	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	140993285	140993285	A	G	SNP	MAGEC1	ENST00000285879	human	ensembl	74_37	+1	known	missense	c.95	p.Q32R	1.000	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGEC1	HGNC	ENSG00000155495				85	0	0	44	35	44.3038
IL1RAPL1	0	genome.wustl.edu	37	X	29417401	29417401	+	Silent	SNP	A	A	C			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	29417401	29417401	A	C	SNP	IL1RAPL1	ENST00000302196	human	ensembl	74_37	+1	known	silent	c.679	p.R227	1.000	smart_Ig_sub,pfscan_Ig-like_dom	pfam_TIR_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_TIR_dom,smart_Ig_sub,smart_Ig_sub2,smart_TIR_dom,pfscan_TIR_dom,pfscan_Ig-like_dom	-	no_errors	IL1RAPL1	HGNC	ENSG00000169306				24	0	0	18	11	37.931
DMD	0	genome.wustl.edu	37	X	32472905	32472905	+	Silent	SNP	A	A	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	32472905	32472905	A	G	SNP	DMD	ENST00000357033	human	ensembl	74_37	-1	known	silent	c.3477	p.T1159	0.906	pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947				65	0	0	51	7	12.069
SSX5	0	genome.wustl.edu	37	X	48053653	48053653	+	Missense_Mutation	SNP	C	C	G			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	48053653	48053653	C	G	SNP	SSX5	ENST00000311798	human	ensembl	74_37	-1	known	missense	c.315	p.K105N	0.000	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	pfam_SSXRD_motif,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	-	no_errors	SSX5	HGNC	ENSG00000165583				67	0	0	55	16	22.5352
ARHGEF9	0	genome.wustl.edu	37	X	62944558	62944558	+	Missense_Mutation	SNP	C	C	T			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	X	62944558	62944558	C	T	SNP	ARHGEF9	ENST00000253401	human	ensembl	74_37	-1	known	missense	c.43	p.A15T	1.000	superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	pfam_DH-domain,pfam_SH3_2,pfam_SH3_domain,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_SH3_domain,smart_SH3_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_DH-domain	-	no_errors	ARHGEF9	HGNC	ENSG00000131089				45	0	0	31	10	24.3902
MGAT2	0	genome.wustl.edu	37	14	50089217	50089220	+	Frame_Shift_Del	DEL	CTAA	CTAA	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	CTAA	CTAA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	50089217	50089220	CTAA	-	DEL	MGAT2	ENST00000305386	human	ensembl	74_37	+1	known	frame_shift_del	c.1231_1234	p.T412fs	0.982:0.985:0.001:0.000	pfam_GlcNAc_II	pfam_GlcNAc_II	-	no_errors	MGAT2	HGNC	ENSG00000168282				83	0	0	47	8	14.5455
MAP3K9	0	genome.wustl.edu	37	14	71275774	71275776	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	CCT	CCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	14	71275774	71275776	CCT	-	DEL	MAP3K9	ENST00000555993	human	ensembl	74_37	-1	known	in_frame_del	c.115_113	p.E38in_frame_del	1.000:1.000:0.998	pirsf_MAPKKK9/10/11	pirsf_MAPKKK9/10/11,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH3_2,pfam_SH3_domain,superfamily_Kinase-like_dom,superfamily_SH3_domain,superfamily_Regulat_G_prot_signal_superfam,smart_SH3_domain,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH3_domain,pfscan_SH3_domain,pfscan_Prot_kinase_dom	-	no_errors	MAP3K9	HGNC	ENSG00000006432				9	0	0	6	2	25
HIC1	0	genome.wustl.edu	37	17	1960405	1960407	+	In_Frame_Del	DEL	GGC	GGC	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GGC	GGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	17	1960405	1960407	GGC	-	DEL	HIC1	ENST00000322941	human	ensembl	74_37	+1	known	in_frame_del	c.478_480	p.G163in_frame_del	1.000:1.000:0.996	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	HIC1	HGNC	ENSG00000177374				8	0	0	4	2	33.3333
TDRD6	0	genome.wustl.edu	37	6	46656493	46656498	+	In_Frame_Del	DEL	GAGCGC	GAGCGC	-			TCGA-IN-A6RJ-01A-21D-A33T-08	TCGA-IN-A6RJ-10A-21D-A33W-08	GAGCGC	GAGCGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	f15817b4-f5a7-4d7b-9e49-cb437ccefdff	364c6679-2a40-48b5-a7ba-a07284771969	6	46656493	46656498	GAGCGC	-	DEL	TDRD6	ENST00000316081	human	ensembl	74_37	+1	known	in_frame_del	c.628_633	p.ER210in_frame_del	0.890:0.996:0.996:0.998:0.998:0.983	NULL	pfam_Tudor,smart_Tudor,pfscan_Tudor	-	no_errors	TDRD6	HGNC	ENSG00000180113				140	0	0	113	11	8.87097
