Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ADAMTS5	0	genome.wustl.edu	37	21	28296629	28296629	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	21	28296629	28296629	G	A	SNP	ADAMTS5	ENST00000284987	human	ensembl	74_37	-1	known	missense	c.2536	p.R846C	1.000	pfam_ADAM_spacer1	pfam_ADAM_spacer1,pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Pept_M12B_ADAM-TS5,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS5	HGNC	ENSG00000154736	tier1	-	-	114	0	0.00	75	21	21.88
ADI1	0	genome.wustl.edu	37	2	3502739	3502739	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	3502739	3502739	C	T	SNP	ADI1	ENST00000327435	human	ensembl	74_37	-1	known	missense	c.535	p.A179T	0.011	superfamily_RmlC_Cupin	pfam_Acireductn_dOase_family,pfam_Cupin_2,pfam_AraC-bd,superfamily_RmlC_Cupin	-	no_errors	ADI1	HGNC	ENSG00000182551	tier1	-	-	62	0	0.00	50	14	21.88
ADRB3	0	genome.wustl.edu	37	8	37823627	37823627	+	Missense_Mutation	SNP	C	C	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	8	37823627	37823627	C	A	SNP	ADRB3	ENST00000345060	human	ensembl	74_37	-1	known	missense	c.361	p.V121L	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_ADRB3_rcpt,prints_GPCR_Rhodpsn,prints_ADR_fam,prints_5HT6_rcpt	-	no_errors	ADRB3	HGNC	ENSG00000188778	tier1	-	-	21	0	0.00	14	7	33.33
AEN	0	genome.wustl.edu	37	15	89172603	89172603	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	15	89172603	89172603	G	A	SNP	AEN	ENST00000379231	human	ensembl	74_37	+1	known	silent	c.687	p.R229	0.000	pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease	pfam_Exonuclease_RNaseT/DNA_pol3,superfamily_RNaseH-like_dom,smart_Exonuclease	-	no_errors	AEN	HGNC	ENSG00000181026	tier1	-	-	95	0	0.00	91	7	7.14
ALKBH5	0	genome.wustl.edu	37	17	18088229	18088229	+	Silent	SNP	T	T	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	17	18088229	18088229	T	A	SNP	ALKBH5	ENST00000399138	human	ensembl	74_37	+1	known	silent	c.672	p.S224	0.088	NULL	NULL	-	no_errors	ALKBH5	HGNC	ENSG00000091542	tier1	-	-	45	0	0.00	38	16	29.63
B4GALNT4	0	genome.wustl.edu	37	11	376456	376456	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	376456	376456	G	A	SNP	B4GALNT4	ENST00000329962	human	ensembl	74_37	+1	known	missense	c.1333	p.D445N	0.484	NULL	pfam_Chond_GalNAc,pfam_PA14,smart_PA14	-	no_errors	B4GALNT4	HGNC	ENSG00000182272	tier1	-	-	33	0	0.00	22	19	46.34
BLZF1	0	genome.wustl.edu	37	1	169349824	169349824	+	Silent	SNP	T	T	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	169349824	169349824	T	C	SNP	BLZF1	ENST00000329281	human	ensembl	74_37	+1	known	silent	c.774	p.R258	0.851	NULL	pfam_Hsk3_like	-	no_errors	BLZF1	HGNC	ENSG00000117475	tier1	-	-	89	0	0.00	73	17	18.89
C10orf68	0	genome.wustl.edu	37	10	33134536	33134536	+	Missense_Mutation	SNP	C	C	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	10	33134536	33134536	C	G	SNP	C10orf68	ENST00000375025	human	ensembl	74_37	+1	known	missense	c.1423	p.Q475E	0.001	NULL	NULL	-	no_errors	C10orf68	HGNC	ENSG00000150076	tier1	-	-	76	0	0.00	56	27	32.53
C16orf93	0	genome.wustl.edu	37	16	30771693	30771693	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	16	30771693	30771693	C	T	SNP	C16orf93	ENST00000543610	human	ensembl	74_37	-1	known	silent	c.381	p.A127	0.512	NULL	NULL	-	no_errors	C16orf93	HGNC	ENSG00000196118	tier1	-	-	64	0	0.00	48	27	36.00
CAMTA1	0	genome.wustl.edu	37	1	7724185	7724185	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	7724185	7724185	C	T	SNP	CAMTA1	ENST00000303635	human	ensembl	74_37	+1	known	silent	c.1578	p.T526	0.962	NULL	pfam_CG-1_dom,pfam_IPT,pfam_IQ_motif_EF-hand-BS,superfamily_Ig_E-set,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_IQ_motif_EF-hand-BS	-	no_errors	CAMTA1	HGNC	ENSG00000171735	tier1	-	-	59	0	0.00	18	24	57.14
CDO1	0	genome.wustl.edu	37	5	115146882	115146882	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	115146882	115146882	C	T	SNP	CDO1	ENST00000250535	human	ensembl	74_37	-1	known	missense	c.379	p.E127K	1.000	pfam_Cys_dOase_I,pfam_Cysteamine_dioxygenase,superfamily_RmlC_Cupin	pfam_Cys_dOase_I,pfam_Cysteamine_dioxygenase,superfamily_RmlC_Cupin	-	no_errors	CDO1	HGNC	ENSG00000129596	tier1	-	-	181	0	0.00	74	81	52.26
CGB1	0	genome.wustl.edu	37	19	49539060	49539060	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	49539060	49539060	C	T	SNP	CGB1	ENST00000301407	human	ensembl	74_37	-1	known	missense	c.275	p.R92H	0.976	pfam_Cys_knot,smart_Gonadotropin_bsu	pfam_Cys_knot,smart_Gonadotropin_bsu	-	no_errors	CGB1	HGNC	ENSG00000267631	tier1	-	-	8	0	0.00	3	10	76.92
CHIAP2	0	genome.wustl.edu	37	1	111824194	111824194	+	RNA	SNP	G	G	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	111824194	111824194	G	C	SNP	CHIAP2	ENST00000369743	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CHIAP2	HGNC	ENSG00000203878	tier1	-	-	22	0	0.00	16	13	44.83
CLEC18B	0	genome.wustl.edu	37	16	74452114	74452114	+	Missense_Mutation	SNP	A	A	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	16	74452114	74452114	A	G	SNP	CLEC18B	ENST00000339953	human	ensembl	74_37	-1	known	missense	c.299	p.L100P	0.000	pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1	pfam_CAP_domain,pfam_C-type_lectin,superfamily_CAP_domain,superfamily_C-type_lectin_fold,smart_Allrgn_V5/Tpx1,smart_EG-like_dom,smart_C-type_lectin,pfscan_EG-like_dom,pfscan_C-type_lectin,prints_Allrgn_V5/Tpx1	-	no_errors	CLEC18B	HGNC	ENSG00000140839	tier1	-	-	26	0	0.00	14	4	22.22
COL4A3BP	0	genome.wustl.edu	37	5	74722305	74722306	+	Splice_Site	INS	-	-	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	74722305	74722306	-	A	INS	COL4A3BP	ENST00000380494	human	ensembl	74_37	-1	known	splice_site_ins	c.733-3_733-2	e5-2	1.000:0.996	-	-	-	no_errors	COL4A3BP	HGNC	ENSG00000113163	tier1			37	0	0.00	32	2	5.88
CSPP1	0	genome.wustl.edu	37	8	67988768	67988768	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	8	67988768	67988768	G	A	SNP	CSPP1	ENST00000262210	human	ensembl	74_37	+1	known	missense	c.259	p.A87T	1.000	NULL	NULL	-	no_errors	CSPP1	HGNC	ENSG00000104218	tier1	-	-	53	0	0.00	52	20	27.78
CT47B1	0	genome.wustl.edu	37	X	120008963	120008963	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	X	120008963	120008963	C	T	SNP	CT47B1	ENST00000371311	human	ensembl	74_37	-1	known	missense	c.562	p.G188S	0.001	NULL	NULL	-	no_errors	CT47B1	HGNC	ENSG00000236446	tier1	-	-	92	0	0.00	52	27	34.18
DCHS1	0	genome.wustl.edu	37	11	6647213	6647213	+	Missense_Mutation	SNP	G	G	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	6647213	6647213	G	T	SNP	DCHS1	ENST00000299441	human	ensembl	74_37	-1	known	missense	c.6669	p.D2223E	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS1	HGNC	ENSG00000166341	tier1	-	-	22	0	0.00	13	8	38.10
DMP1	0	genome.wustl.edu	37	4	88584286	88584286	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	4	88584286	88584286	C	T	SNP	DMP1	ENST00000339673	human	ensembl	74_37	+1	known	silent	c.1356	p.D452	0.006	pfam_DMP1	pfam_DMP1	-	no_errors	DMP1	HGNC	ENSG00000152592	tier1	rs149026481	-	53	0	0.00	11	29	70.73
DPP10	0	genome.wustl.edu	37	2	116447443	116447443	+	Missense_Mutation	SNP	A	A	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	116447443	116447443	A	C	SNP	DPP10	ENST00000393147	human	ensembl	74_37	+1	known	missense	c.534	p.E178D	1.000	pfam_Peptidase_S9B	pfam_Peptidase_S9B,pfam_Peptidase_S9	-	no_errors	DPP10	HGNC	ENSG00000175497	tier1	-	-	54	0	0.00	37	27	41.54
EDAR	0	genome.wustl.edu	37	2	109545680	109545680	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	109545680	109545680	G	A	SNP	EDAR	ENST00000376651	human	ensembl	74_37	-1	known	silent	c.330	p.D110	0.818	NULL	pfam_Death_domain,superfamily_DEATH-like_dom	-	no_errors	EDAR	HGNC	ENSG00000135960	tier1	-	-	35	0	0.00	35	18	33.96
EFCAB1	0	genome.wustl.edu	37	8	49647837	49647837	+	RNA	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	8	49647837	49647837	C	T	SNP	EFCAB1	ENST00000521721	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	EFCAB1	HGNC	ENSG00000034239	tier1	-	-	33	0	0.00	15	6	28.57
ENSG00000205790	0	genome.wustl.edu	37	19	4682879	4682880	+	RNA	DEL	AG	AG	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	AG	AG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	4682879	4682880	AG	-	DEL	ENSG00000205790	ENST00000381796	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.006	-	-	-	no_errors	AC005594.3	Clone_based_vega_gene	ENSG00000205790	tier1			8	0	0.00	2	3	60.00
ENSG00000232623	0	genome.wustl.edu	37	21	33678898	33678898	+	RNA	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	21	33678898	33678898	G	A	SNP	ENSG00000232623	ENST00000450936	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AP000266.7	Clone_based_vega_gene	ENSG00000232623	tier1	-	-	22	0	0.00	12	4	25.00
FABP1	0	genome.wustl.edu	37	2	88425812	88425812	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	88425812	88425812	G	A	SNP	FABP1	ENST00000295834	human	ensembl	74_37	-1	known	silent	c.123	p.I41	0.958	pfam_Lipocln_cytosolic_FA-bd_dom,superfamily_Calycin-like	pfam_Lipocln_cytosolic_FA-bd_dom,superfamily_Calycin-like,prints_Fatty_acid-bd	-	no_errors	FABP1	HGNC	ENSG00000163586	tier1	-	-	348	0	0.00	222	152	40.64
FAM24A	0	genome.wustl.edu	37	10	124672299	124672299	+	Silent	SNP	T	T	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	10	124672299	124672299	T	G	SNP	FAM24A	ENST00000368894	human	ensembl	74_37	+1	known	silent	c.147	p.A49	0.000	NULL	NULL	-	no_errors	FAM24A	HGNC	ENSG00000203795	tier1	-	-	100	0	0.00	88	21	19.27
FAT2	0	genome.wustl.edu	37	5	150901275	150901275	+	Missense_Mutation	SNP	G	G	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	150901275	150901275	G	T	SNP	FAT2	ENST00000261800	human	ensembl	74_37	-1	known	missense	c.10879	p.L3627M	0.945	smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT2	HGNC	ENSG00000086570	tier1	-	-	39	0	0.00	44	12	21.43
FSTL4	0	genome.wustl.edu	37	5	132560842	132560842	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	132560842	132560842	G	A	SNP	FSTL4	ENST00000265342	human	ensembl	74_37	-1	known	missense	c.1312	p.L438F	1.000	NULL	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Kazal_dom,smart_Kazal_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_EF_hand_dom,pfscan_Ig-like_dom	-	no_errors	FSTL4	HGNC	ENSG00000053108	tier1	-	-	45	0	0.00	42	15	26.32
GABRE	0	genome.wustl.edu	37	X	151124295	151124295	+	Missense_Mutation	SNP	G	G	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	X	151124295	151124295	G	T	SNP	GABRE	ENST00000370328	human	ensembl	74_37	-1	known	missense	c.822	p.S274R	0.996	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,prints_Neur_channel,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAe_rcpt,prints_GABAAa_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRE	HGNC	ENSG00000102287	tier1	-	-	124	0	0.00	103	55	34.81
GFPT2	0	genome.wustl.edu	37	5	179751274	179751274	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	179751274	179751274	C	T	SNP	GFPT2	ENST00000253778	human	ensembl	74_37	-1	known	silent	c.708	p.K236	0.029	NULL	pfam_SIS,pfam_GATase_dom,tigrfam_GlmS_trans	-	no_errors	GFPT2	HGNC	ENSG00000131459	tier1	-	-	48	0	0.00	23	16	41.03
GPR112	0	genome.wustl.edu	37	X	135428768	135428768	+	Missense_Mutation	SNP	C	C	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	X	135428768	135428768	C	G	SNP	GPR112	ENST00000370652	human	ensembl	74_37	+1	known	missense	c.2903	p.A968G	0.011	NULL	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	GPR112	HGNC	ENSG00000156920	tier1	-	-	191	0	0.00	200	33	14.16
HIST1H3I	0	genome.wustl.edu	37	6	27840030	27840030	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	6	27840030	27840030	C	T	SNP	HIST1H3I	ENST00000328488	human	ensembl	74_37	-1	known	missense	c.64	p.A22T	1.000	superfamily_Histone-fold,prints_Histone_H3	pfam_Histone_core_D,superfamily_Histone-fold,smart_Histone_H3,prints_Histone_H3	-	no_errors	HIST1H3I	HGNC	ENSG00000182572	tier1	-	-	78	0	0.00	54	10	15.62
HKR1	0	genome.wustl.edu	37	19	37854085	37854085	+	Missense_Mutation	SNP	A	A	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	37854085	37854085	A	G	SNP	HKR1	ENST00000324411	human	ensembl	74_37	+1	known	missense	c.1388	p.H463R	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	HKR1	HGNC	ENSG00000181666	tier1	-	-	65	0	0.00	39	60	60.61
HSPH1	0	genome.wustl.edu	37	13	31722526	31722526	+	Nonsense_Mutation	SNP	G	G	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	13	31722526	31722526	G	C	SNP	HSPH1	ENST00000445273	human	ensembl	74_37	-1	known	nonsense	c.1235	p.S412*	1.000	pfam_Hsp_70_fam	pfam_Hsp_70_fam,pfam_MreB_Mrl,prints_Hsp_70_fam	-	no_errors	HSPH1	HGNC	ENSG00000120694	tier1	-	-	133	0	0.00	133	17	11.33
HTR5A	0	genome.wustl.edu	37	7	154875950	154875950	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	7	154875950	154875950	G	A	SNP	HTR5A	ENST00000287907	human	ensembl	74_37	+1	known	missense	c.827	p.R276Q	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_5HT5A_rcpt,prints_5HT_rcpt	-	no_errors	HTR5A	HGNC	ENSG00000157219	tier1	-	-	41	0	0.00	30	20	40.00
ITPR2	0	genome.wustl.edu	37	12	26864160	26864160	+	Nonsense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	26864160	26864160	C	T	SNP	ITPR2	ENST00000381340	human	ensembl	74_37	-1	known	nonsense	c.897	p.W299*	1.000	pfam_MIR_motif,superfamily_MIR_motif,smart_MIR_motif,prints_InsP3_rcpt-bd	pfam_Ca-rel_channel,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ARM-type_fold,smart_MIR_motif,prints_InsP3_rcpt-bd,pfscan_MIR_motif	-	no_errors	ITPR2	HGNC	ENSG00000123104	tier1	-	-	53	0	0.00	38	27	41.54
KDELR2	0	genome.wustl.edu	37	7	6523688	6523689	+	In_Frame_Ins	INS	-	-	GGC			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	7	6523688	6523689	-	GGC	INS	KDELR2	ENST00000258739	human	ensembl	74_37	-1	known	in_frame_ins	c.1_2	p.0in_frame_insA	1.000:1.000	NULL	pfam_ER_ret_rcpt,prints_ER_ret_rcpt	-	no_errors	KDELR2	HGNC	ENSG00000136240	tier1			9	0	0.00	16	5	23.81
KRTAP19-3	0	genome.wustl.edu	37	21	31864221	31864221	+	Missense_Mutation	SNP	C	C	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	21	31864221	31864221	C	G	SNP	KRTAP19-3	ENST00000334063	human	ensembl	74_37	-1	known	missense	c.55	p.G19R	0.012	pfam_KRTAP_type6/8/16/19/20	pfam_KRTAP_type6/8/16/19/20	-	no_errors	KRTAP19-3	HGNC	ENSG00000244025	tier1	-	-	182	0	0.00	119	34	22.22
MAP1B	0	genome.wustl.edu	37	5	71492637	71492637	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	71492637	71492637	C	T	SNP	MAP1B	ENST00000296755	human	ensembl	74_37	+1	known	missense	c.3455	p.T1152M	0.949	NULL	pfam_MAP1B_neuraxin	-	no_errors	MAP1B	HGNC	ENSG00000131711	tier1	-	-	52	0	0.00	39	10	20.41
MAP2K7	0	genome.wustl.edu	37	19	7976138	7976138	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	7976138	7976138	G	A	SNP	MAP2K7	ENST00000545011	human	ensembl	74_37	+1	known	missense	c.985	p.E329K	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP2K7	HGNC	ENSG00000076984	tier1	-	-	45	0	0.00	14	20	58.82
METTL13	0	genome.wustl.edu	37	1	171753018	171753018	+	Missense_Mutation	SNP	A	A	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	171753018	171753018	A	G	SNP	METTL13	ENST00000361735	human	ensembl	74_37	+1	known	missense	c.292	p.M98V	0.995	pfam_Methyltransf_11	pfam_Methyltransf_11,pfam_Spermidine/spermine_synthase	-	no_errors	METTL13	HGNC	ENSG00000010165	tier1	-	-	57	0	0.00	69	34	33.01
METTL24	0	genome.wustl.edu	37	6	110620291	110620291	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	6	110620291	110620291	C	T	SNP	METTL24	ENST00000338882	human	ensembl	74_37	-1	known	missense	c.620	p.R207H	1.000	NULL	NULL	-	no_errors	METTL24	HGNC	ENSG00000053328	tier1	-	-	114	0	0.00	91	5	5.21
MUC16	0	genome.wustl.edu	37	19	9067374	9067374	+	Missense_Mutation	SNP	G	G	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	9067374	9067374	G	T	SNP	MUC16	ENST00000397910	human	ensembl	74_37	-1	known	missense	c.20072	p.T6691K	0.001	NULL	pfam_SEA_dom,smart_SEA_dom,pfscan_SEA_dom	-	no_errors	MUC16	HGNC	ENSG00000181143	tier1	-	-	163	0	0.00	34	65	65.66
NADK	0	genome.wustl.edu	37	1	1684347	1684348	+	In_Frame_Ins	INS	-	-	CCT			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	1684347	1684348	-	CCT	INS	NADK	ENST00000344463	human	ensembl	74_37	-1	known	in_frame_ins	c.1772_1771	p.591in_frame_insE	0.814:0.794	NULL	pfam_PolyP/ATP_NADK_prd,superfamily_ATP-NAD_kinase_PpnK-typ	-	no_errors	NADK	HGNC	ENSG00000008130	tier1			10	0	0.00	15	8	34.78
NCOA6	0	genome.wustl.edu	37	20	33345744	33345744	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	20	33345744	33345744	C	T	SNP	NCOA6	ENST00000359003	human	ensembl	74_37	-1	known	silent	c.807	p.Q269	0.002	NULL	NULL	-	no_errors	NCOA6	HGNC	ENSG00000198646	tier1	-	-	35	0	0.00	55	6	9.84
NOX1	0	genome.wustl.edu	37	X	100104298	100104298	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	X	100104298	100104298	G	A	SNP	NOX1	ENST00000372966	human	ensembl	74_37	-1	known	missense	c.1414	p.L472F	1.000	pfam_Fe_red_NAD-bd_6	pfam_Fe_red_NAD-bd_6,pfam_FAD-bd_8,pfam_Fe3_Rdtase_TM_dom,pfam_OxRdtase_FAD-bd_dom,superfamily_Riboflavin_synthase-like_b-brl,prints_Cyt_b245_heavy_chain	-	no_errors	NOX1	HGNC	ENSG00000007952	tier1	-	-	71	0	0.00	49	29	37.18
NRG1	0	genome.wustl.edu	37	8	32599536	32599536	+	Nonsense_Mutation	SNP	G	G	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	8	32599536	32599536	G	T	SNP	NRG1	ENST00000338921	human	ensembl	74_37	+1	known	nonsense	c.643	p.G215*	1.000	smart_EG-like_dom,pfscan_EG-like_dom	pfam_Neuregulin_1_C,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Ig-like_dom,prints_Neuregulin	-	no_errors	NRG1	HGNC	ENSG00000157168	tier1	-	-	54	0	0.00	59	15	20.27
OBSL1	0	genome.wustl.edu	37	2	220420907	220420907	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	220420907	220420907	G	A	SNP	OBSL1	ENST00000404537	human	ensembl	74_37	-1	known	missense	c.4444	p.R1482C	1.000	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	OBSL1	HGNC	ENSG00000124006	tier1	-	-	18	0	0.00	15	9	37.50
OR13C4	0	genome.wustl.edu	37	9	107288743	107288743	+	Missense_Mutation	SNP	T	T	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	9	107288743	107288743	T	A	SNP	OR13C4	ENST00000277216	human	ensembl	74_37	-1	known	missense	c.748	p.I250L	0.993	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR13C4	HGNC	ENSG00000148136	tier1	-	-	84	0	0.00	55	25	31.25
OR52A5	0	genome.wustl.edu	37	11	5153859	5153859	+	Missense_Mutation	SNP	T	T	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	5153859	5153859	T	G	SNP	OR52A5	ENST00000307388	human	ensembl	74_37	-1	known	missense	c.14	p.N5T	0.974	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR52A5	HGNC	ENSG00000171944	tier1	-	-	39	0	0.00	36	9	20.00
OR6C4	0	genome.wustl.edu	37	12	55945712	55945712	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	55945712	55945712	G	A	SNP	OR6C4	ENST00000394256	human	ensembl	74_37	+1	known	silent	c.702	p.K234	0.827	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6C4	HGNC	ENSG00000179626	tier1	-	-	103	0	0.00	60	42	41.18
OR6K2	0	genome.wustl.edu	37	1	158669693	158669693	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	158669693	158669693	C	T	SNP	OR6K2	ENST00000359610	human	ensembl	74_37	-1	known	silent	c.750	p.S250	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6K2	HGNC	ENSG00000196171	tier1	-	-	36	0	0.00	27	14	33.33
PAK7	0	genome.wustl.edu	37	20	9560913	9560913	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	20	9560913	9560913	G	A	SNP	PAK7	ENST00000353224	human	ensembl	74_37	-1	known	missense	c.869	p.S290L	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_CRIB_dom,superfamily_Kinase-like_dom,smart_CRIB_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_CRIB_dom,pfscan_Prot_kinase_dom	-	no_errors	PAK7	HGNC	ENSG00000101349	tier1	-	-	134	0	0.00	109	48	30.57
PHLDA2	0	genome.wustl.edu	37	11	2950237	2950238	+	Frame_Shift_Ins	INS	-	-	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	2950237	2950238	-	G	INS	PHLDA2	ENST00000314222	human	ensembl	74_37	-1	known	frame_shift_ins	c.358_357	p.A119fs	0.993:0.970	NULL	pfam_Pleckstrin_homology,smart_Pleckstrin_homology	-	no_errors	PHLDA2	HGNC	ENSG00000181649	tier1			10	0	0.00	3	2	40.00
PHLPP1	0	genome.wustl.edu	37	18	60639816	60639816	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	18	60639816	60639816	C	T	SNP	PHLPP1	ENST00000262719	human	ensembl	74_37	+1	known	silent	c.3630	p.D1210	0.994	pfam_PP2C-like_dom,superfamily_PP2C-like_dom,smart_PP2C-like_dom	pfam_PP2C-like_dom,pfam_Leu-rich_rpt,superfamily_PP2C-like_dom,smart_Leu-rich_rpt_typical-subtyp,smart_PP2C-like_dom,pfscan_Pleckstrin_homology	-	no_errors	PHLPP1	HGNC	ENSG00000081913	tier1	-	-	50	0	0.00	34	20	37.04
PRSS23	0	genome.wustl.edu	37	11	86518708	86518708	+	Missense_Mutation	SNP	T	T	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	86518708	86518708	T	A	SNP	PRSS23	ENST00000280258	human	ensembl	74_37	+1	known	missense	c.23	p.L8H	0.869	NULL	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom	-	no_errors	PRSS23	HGNC	ENSG00000150687	tier1	-	-	145	0	0.00	61	64	51.20
PTP4A2	0	genome.wustl.edu	37	1	32384717	32384717	+	RNA	DEL	A	A	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	32384717	32384717	A	-	DEL	PTP4A2	ENST00000532289	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PTP4A2	HGNC	ENSG00000184007	tier1			30	0	0.00	39	4	9.30
RAB3GAP2	0	genome.wustl.edu	37	1	220364485	220364485	+	Missense_Mutation	SNP	C	C	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	220364485	220364485	C	A	SNP	RAB3GAP2	ENST00000358951	human	ensembl	74_37	-1	known	missense	c.1412	p.R471I	0.990	superfamily_WD40_repeat_dom	superfamily_WD40_repeat_dom	-	no_errors	RAB3GAP2	HGNC	ENSG00000118873	tier1	-	-	124	0	0.00	94	60	38.96
RBM6	0	genome.wustl.edu	37	3	50004794	50004794	+	RNA	DEL	A	A	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	3	50004794	50004794	A	-	DEL	RBM6	ENST00000488807	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	RBM6	HGNC	ENSG00000004534	tier1			17	0	0.00	15	4	21.05
RHBDD2	0	genome.wustl.edu	37	7	75517750	75517750	+	RNA	DEL	C	C	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	7	75517750	75517750	C	-	DEL	RHBDD2	ENST00000468304	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.008	-	-	-	no_errors	RHBDD2	HGNC	ENSG00000005486	tier1			24	0	0.00	26	16	38.10
RHEB	0	genome.wustl.edu	37	7	151164206	151164206	+	Nonstop_Mutation	SNP	C	C	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	7	151164206	151164206	C	A	SNP	RHEB	ENST00000262187	human	ensembl	74_37	-1	known	nonstop	c.554	p.*185L	0.964	NULL	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RHEB	HGNC	ENSG00000106615	tier1	-	-	32	0	0.00	31	15	32.61
RNA5-8SP6	0	genome.wustl.edu	37	Y	10037863	10037863	+	RNA	DEL	C	C	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	Y	10037863	10037863	C	-	DEL	RNA5-8SP6	ENST00000515896	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RNA5-8SP6	HGNC	ENSG00000251705	tier1			15	0	0.00	17	5	22.73
RNF10	0	genome.wustl.edu	37	12	120990361	120990361	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	120990361	120990361	C	T	SNP	RNF10	ENST00000413266	human	ensembl	74_37	+1	known	silent	c.414	p.I138	1.000	NULL	pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF10	HGNC	ENSG00000022840	tier1	-	-	72	0	0.00	43	39	47.56
RPL24	0	genome.wustl.edu	37	3	101404703	101404703	+	Missense_Mutation	SNP	A	A	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	3	101404703	101404703	A	G	SNP	RPL24	ENST00000394077	human	ensembl	74_37	-1	known	missense	c.151	p.W51R	1.000	pfam_Ribosomal_L24e_rel	pfam_Ribosomal_L24e_rel,smart_TRASH_dom	-	no_errors	RPL24	HGNC	ENSG00000114391	tier1	-	-	105	0	0.00	125	25	16.67
RREB1	0	genome.wustl.edu	37	6	7211150	7211151	+	Frame_Shift_Ins	INS	-	-	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	6	7211150	7211151	-	A	INS	RREB1	ENST00000379938	human	ensembl	74_37	+1	known	frame_shift_ins	c.539_540	p.E181fs	0.991:0.878	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	RREB1	HGNC	ENSG00000124782	tier1			137	0	0.00	80	43	34.96
RYR2	0	genome.wustl.edu	37	1	237993765	237993765	+	RNA	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	237993765	237993765	G	A	SNP	RYR2	ENST00000462585	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RYR2	HGNC	ENSG00000198626	tier1	-	-	39	0	0.00	20	11	35.48
SALL3	0	genome.wustl.edu	37	18	76757283	76757283	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	18	76757283	76757283	G	A	SNP	SALL3	ENST00000537592	human	ensembl	74_37	+1	known	silent	c.3864	p.T1288	0.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SALL3	HGNC	ENSG00000256463	tier1	-	-	175	0	0.00	153	82	34.89
SH2B3	0	genome.wustl.edu	37	12	111885301	111885301	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	111885301	111885301	C	T	SNP	SH2B3	ENST00000341259	human	ensembl	74_37	+1	putative	missense	c.1189	p.R397W	0.982	pfam_SH2,smart_SH2,pfscan_SH2	pfam_Phe_ZIP,pfam_SH2,pfam_Pleckstrin_homology,superfamily_Phe_ZIP,smart_Pleckstrin_homology,smart_SH2,pfscan_SH2,prints_SH2	-	no_errors	SH2B3	HGNC	ENSG00000111252	tier1	-	-	93	0	0.00	59	32	35.16
SLC11A1	0	genome.wustl.edu	37	2	219259676	219259676	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	219259676	219259676	C	T	SNP	SLC11A1	ENST00000233202	human	ensembl	74_37	+1	known	missense	c.1571	p.A524V	0.904	NULL	pfam_NRAMP-like,prints_NRAMP-like,tigrfam_NRAMP-like	-	no_errors	SLC11A1	HGNC	ENSG00000018280	tier1	-	-	21	0	0.00	20	7	25.93
SLC25A41	0	genome.wustl.edu	37	19	6429824	6429825	+	Frame_Shift_Del	DEL	CA	CA	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	CA	CA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	6429824	6429825	CA	-	DEL	SLC25A41	ENST00000321510	human	ensembl	74_37	-1	known	frame_shift_del	c.535_534	p.C178fs	0.000:0.000	superfamily_Mt_carrier_dom	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier,prints_Mit_carrier	-	no_errors	SLC25A41	HGNC	ENSG00000181240	tier1			32	0	0.00	8	2	20.00
SLC4A1AP	0	genome.wustl.edu	37	2	27892203	27892203	+	Silent	SNP	T	T	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	27892203	27892203	T	C	SNP	SLC4A1AP	ENST00000326019	human	ensembl	74_37	+1	known	silent	c.1294	p.L432	0.993	pfam_dsRNA-bd_dom	pfam_FHA_dom,pfam_dsRNA-bd_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,pfscan_FHA_dom	-	no_errors	SLC4A1AP	HGNC	ENSG00000163798	tier1	-	-	181	0	0.00	153	76	33.19
SLCO1A2	0	genome.wustl.edu	37	12	21448672	21448672	+	Missense_Mutation	SNP	A	A	G			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	21448672	21448672	A	G	SNP	SLCO1A2	ENST00000307378	human	ensembl	74_37	-1	known	missense	c.1130	p.M377T	1.000	pfam_OA_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1A2	HGNC	ENSG00000084453	tier1	-	-	64	0	0.00	47	39	45.35
SLCO1C1	0	genome.wustl.edu	37	12	20905256	20905256	+	Missense_Mutation	SNP	C	C	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	20905256	20905256	C	A	SNP	SLCO1C1	ENST00000381552	human	ensembl	74_37	+1	known	missense	c.2036	p.T679N	0.999	NULL	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,tigrfam_OA_transporter	-	no_errors	SLCO1C1	HGNC	ENSG00000139155	tier1	-	-	35	0	0.00	46	20	30.30
SORCS3	0	genome.wustl.edu	37	10	106937891	106937891	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	10	106937891	106937891	G	A	SNP	SORCS3	ENST00000369701	human	ensembl	74_37	+1	known	missense	c.1969	p.G657R	1.000	smart_VPS10	pfam_PKD_dom,superfamily_PKD_dom,smart_VPS10,pfscan_PKD_dom	-	no_errors	SORCS3	HGNC	ENSG00000156395	tier1	-	-	44	0	0.00	16	23	58.97
SPINK5	0	genome.wustl.edu	37	5	147449998	147449998	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	147449998	147449998	C	T	SNP	SPINK5	ENST00000359874	human	ensembl	74_37	+1	known	missense	c.194	p.T65M	0.000	NULL	pfam_Kazal_dom,smart_Kazal_dom	-	no_errors	SPINK5	HGNC	ENSG00000133710	tier1	-	-	102	0	0.00	43	32	42.67
SPRY4	0	genome.wustl.edu	37	5	141694310	141694310	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	5	141694310	141694310	C	T	SNP	SPRY4	ENST00000344120	human	ensembl	74_37	-1	known	missense	c.433	p.D145N	0.999	NULL	pfam_Sprouty	-	no_errors	SPRY4	HGNC	ENSG00000187678	tier1	-	-	60	0	0.00	66	20	23.26
SPTBN2	0	genome.wustl.edu	37	11	66460884	66460884	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	66460884	66460884	G	A	SNP	SPTBN2	ENST00000309996	human	ensembl	74_37	-1	known	missense	c.4627	p.R1543W	1.000	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTBN2	HGNC	ENSG00000173898	tier1	-	-	28	0	0.00	26	6	18.75
ST3GAL2	0	genome.wustl.edu	37	16	70422404	70422404	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	16	70422404	70422404	G	A	SNP	ST3GAL2	ENST00000342907	human	ensembl	74_37	-1	known	silent	c.579	p.S193	1.000	pfam_Glyco_trans_29,pirsf_Sialyl_trans	pfam_Glyco_trans_29,pirsf_Sialyl_trans	-	no_errors	ST3GAL2	HGNC	ENSG00000157350	tier1	-	-	95	0	0.00	80	11	11.96
SYNE1	0	genome.wustl.edu	37	6	152671759	152671759	+	Missense_Mutation	SNP	T	T	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	6	152671759	152671759	T	C	SNP	SYNE1	ENST00000265368	human	ensembl	74_37	-1	known	missense	c.11727	p.I3909M	0.000	pfam_Spectrin_repeat,superfamily_Calpain_domain_III,superfamily_ABC1_TM_dom,smart_Spectrin/alpha-actinin	pfam_Spectrin_repeat,pfam_CH-domain,pfam_KASH,superfamily_CH-domain,superfamily_Calpain_domain_III,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,pfscan_CH-domain,pfscan_KASH	-	no_errors	SYNE1	HGNC	ENSG00000131018	tier1	-	-	100	0	0.00	76	19	20.00
TIMM8B	0	genome.wustl.edu	37	11	111956156	111956156	+	Missense_Mutation	SNP	T	T	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	11	111956156	111956156	T	C	SNP	TIMM8B	ENST00000541231	human	ensembl	74_37	-1	known	missense	c.160	p.K54E	1.000	pfam_Tim10/DDP_fam_Znf,superfamily_Tim10/DDP_fam_Znf	pfam_Tim10/DDP_fam_Znf,superfamily_Tim10/DDP_fam_Znf	-	no_errors	TIMM8B	HGNC	ENSG00000150779	tier1	-	-	36	0	0.00	21	21	50.00
TMPRSS15	0	genome.wustl.edu	37	21	19666654	19666654	+	Nonsense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	21	19666654	19666654	G	A	SNP	TMPRSS15	ENST00000284885	human	ensembl	74_37	-1	known	nonsense	c.2419	p.R807*	0.000	pfam_Peptidase_S1,pfam_Peptidase_S1A_nudel,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_CUB_dom,pfam_MAM_dom,pfam_SEA_dom,pfam_LDrepeatLR_classA_rpt,pfam_Peptidase_S1A_nudel,pfam_SRCR,superfamily_Trypsin-like_Pept_dom,superfamily_ConA-like_lec_gl_sf,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,superfamily_Srcr_rcpt-rel,smart_SEA_dom,smart_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_MAM_dom,smart_Srcr_rcpt-rel,smart_Peptidase_S1,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_MAM_dom,pfscan_SEA_dom,pfscan_SRCR,pfscan_Peptidase_S1,prints_Peptidase_S1A,prints_LDrepeatLR_classA_rpt	-	no_errors	TMPRSS15	HGNC	ENSG00000154646	tier1	-	-	97	0	0.00	84	22	20.75
TNS1	0	genome.wustl.edu	37	2	218678007	218678007	+	Missense_Mutation	SNP	T	T	C			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	2	218678007	218678007	T	C	SNP	TNS1	ENST00000171887	human	ensembl	74_37	-1	known	missense	c.4573	p.R1525G	0.997	pfam_SH2,smart_SH2,pfscan_SH2	pfam_PTB,pfam_Tensin_phosphatase_C2-dom,pfam_SH2,superfamily_C2_dom,smart_Tyr_Pase_cat,smart_SH2,smart_PTB/PI_dom,pfscan_SH2,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	TNS1	HGNC	ENSG00000079308				12	0	0.00	16	4	20.00
USP30-AS1	0	genome.wustl.edu	37	12	109490427	109490429	+	RNA	DEL	CGG	CGG	-			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	CGG	CGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	12	109490427	109490429	CGG	-	DEL	USP30-AS1	ENST00000478808	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000:0.000	-	-	-	no_errors	USP30-AS1	HGNC	ENSG00000256262	tier1			8	0	0.00	5	2	28.57
VSIG8	0	genome.wustl.edu	37	1	159827562	159827562	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	1	159827562	159827562	C	T	SNP	VSIG8	ENST00000368100	human	ensembl	74_37	-1	known	missense	c.625	p.E209K	1.000	pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_Ig_V-set,pfam_Ig_I-set,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	VSIG8	HGNC	ENSG00000243284	tier1	-	-	49	0	0.00	33	9	21.43
VTI1B	0	genome.wustl.edu	37	14	68123303	68123303	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	14	68123303	68123303	G	A	SNP	VTI1B	ENST00000554659	human	ensembl	74_37	-1	known	missense	c.370	p.R124W	0.999	NULL	pfam_Vesicle_trsprt_v-SNARE_N,superfamily_t-SNARE,smart_T_SNARE_dom	-	no_errors	VTI1B	HGNC	ENSG00000100568	tier1	-	-	104	0	0.00	88	46	34.33
WDR7	0	genome.wustl.edu	37	18	54385288	54385288	+	Missense_Mutation	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	18	54385288	54385288	C	T	SNP	WDR7	ENST00000254442	human	ensembl	74_37	+1	known	missense	c.1672	p.R558C	1.000	superfamily_Quinonprotein_ADH-like_supfam,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_Quinonprotein_ADH-like_supfam,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDR7	HGNC	ENSG00000091157	tier1	-	-	104	0	0.00	21	43	67.19
XYLT2	0	genome.wustl.edu	37	17	48433886	48433886	+	Silent	SNP	C	C	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	17	48433886	48433886	C	T	SNP	XYLT2	ENST00000017003	human	ensembl	74_37	+1	known	silent	c.1497	p.P499	0.858	NULL	pfam_XylT,pfam_Glyco_trans_14	-	no_errors	XYLT2	HGNC	ENSG00000015532	tier1	-	-	75	0	0.00	53	22	29.33
ZNF182	0	genome.wustl.edu	37	X	47835938	47835938	+	Nonsense_Mutation	SNP	A	A	T			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	X	47835938	47835938	A	T	SNP	ZNF182	ENST00000305127	human	ensembl	74_37	-1	known	nonsense	c.1548	p.C516*	0.758	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF182	HGNC	ENSG00000147118	tier1	-	-	61	0	0.00	83	10	10.75
ZNF23	0	genome.wustl.edu	37	16	71483580	71483580	+	Silent	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	16	71483580	71483580	G	A	SNP	ZNF23	ENST00000357254	human	ensembl	74_37	-1	known	silent	c.348	p.P116	0.000	NULL	pfam_Znf_C2H2,superfamily_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF23	HGNC	ENSG00000167377	tier1	-	-	165	0	0.00	130	48	26.97
ZNF296	0	genome.wustl.edu	37	19	45575385	45575385	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	19	45575385	45575385	G	A	SNP	ZNF296	ENST00000303809	human	ensembl	74_37	-1	known	missense	c.902	p.A301V	0.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF296	HGNC	ENSG00000170684	tier1	rs142135795	-	58	0	0.00	102	12	10.53
ZNF517	0	genome.wustl.edu	37	8	146033091	146033091	+	Missense_Mutation	SNP	G	G	A			TCGA-R5-A7ZR-01A-11D-A34U-08	TCGA-R5-A7ZR-10A-01D-A34X-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d6a86aef-1ede-46b8-b2f3-5a552c2c3aaa	565ff634-9730-4c9c-94a6-7ef96887e4f3	8	146033091	146033091	G	A	SNP	ZNF517	ENST00000359971	human	ensembl	74_37	+1	known	missense	c.790	p.G264S	0.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF517	HGNC	ENSG00000197363	tier1	rs147246151	-	22	0	0.00	30	5	14.29
