Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ADAM29	0	genome.wustl.edu	37	4	175897786	175897786	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	175897786	175897786	T	C	SNP	ADAM29	ENST00000359240	human	ensembl	74_37	+1	known	silent	c.1110	p.S370	0.286	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_Peptidase_M12B,pfam_ADAM_Cys-rich,pfam_Peptidase_M12B_N,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM29	HGNC	ENSG00000168594	tier1	-	-	178	0	0.00	76	73	48.99
ADAMTS8	0	genome.wustl.edu	37	11	130286907	130286907	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	130286907	130286907	C	T	SNP	ADAMTS8	ENST00000257359	human	ensembl	74_37	-1	known	missense	c.1024	p.D342N	1.000	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Pept_M12B_ADAM-TS8,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS8	HGNC	ENSG00000134917	tier1	-	-	152	0	0.00	52	36	40.45
ADAMTSL3	0	genome.wustl.edu	37	15	84651619	84651619	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	84651619	84651619	T	A	SNP	ADAMTSL3	ENST00000286744	human	ensembl	74_37	+1	known	missense	c.3239	p.F1080Y	0.128	NULL	pfam_Thrombospondin_1_rpt,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_Ig_sub,smart_Ig_sub2,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Ig-like_dom,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTSL3	HGNC	ENSG00000156218	tier1	-	-	84	0	0.00	39	17	30.36
AGBL1	0	genome.wustl.edu	37	15	86800174	86800174	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	86800174	86800174	G	A	SNP	AGBL1	ENST00000441037	human	ensembl	74_37	+1	known	missense	c.688	p.V230I	0.961	superfamily_ARM-type_fold	pfam_Peptidase_M14,superfamily_ARM-type_fold	-	no_errors	AGBL1	HGNC	ENSG00000166748	tier1	-	-	53	0	0.00	14	16	53.33
ALDH1B1	0	genome.wustl.edu	37	9	38397201	38397201	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	38397201	38397201	A	-	DEL	ALDH1B1	ENST00000377698	human	ensembl	74_37	+1	known	frame_shift_del	c.1456	p.K486fs	1.000	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	-	no_errors	ALDH1B1	HGNC	ENSG00000137124	tier1			48	0	0.00	14	2	12.50
ALOX5	0	genome.wustl.edu	37	10	45878099	45878099	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	45878099	45878099	G	A	SNP	ALOX5	ENST00000374391	human	ensembl	74_37	+1	known	missense	c.319	p.D107N	0.999	pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,pfscan_PLAT/LH2_dom	pfam_LipOase_C,pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_LipOase_mml,prints_LipOase_C,pfscan_PLAT/LH2_dom	-	no_errors	ALOX5	HGNC	ENSG00000012779	tier1	-	-	31	0	0.00	13	4	23.53
ANGPT1	0	genome.wustl.edu	37	8	108315466	108315467	+	Splice_Site	INS	-	-	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	108315466	108315467	-	C	INS	ANGPT1	ENST00000517746	human	ensembl	74_37	-1	known	splice_site_ins	c.936+1_936+1	e5+1	1.000:1.000	-	-	-	no_errors	ANGPT1	HGNC	ENSG00000154188	tier1			66	0	0.00	41	18	30.51
ANGPT1	0	genome.wustl.edu	37	8	108315469	108315469	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	108315469	108315469	T	G	SNP	ANGPT1	ENST00000517746	human	ensembl	74_37	-1	known	missense	c.935	p.K312T	1.000	pfam_Fibrinogen_a/b/g_C_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	pfam_Fibrinogen_a/b/g_C_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	-	no_errors	ANGPT1	HGNC	ENSG00000154188	tier1	-	-	71	0	0.00	40	20	32.26
ANO3	0	genome.wustl.edu	37	11	26656592	26656592	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	26656592	26656592	T	G	SNP	ANO3	ENST00000256737	human	ensembl	74_37	+1	known	missense	c.2018	p.L673R	1.000	pfam_Anoctamin	pfam_Anoctamin	-	no_errors	ANO3	HGNC	ENSG00000134343	tier1	-	-	111	0	0.00	44	18	29.03
AR	0	genome.wustl.edu	37	X	66941783	66941783	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	66941783	66941783	A	C	SNP	AR	ENST00000374690	human	ensembl	74_37	+1	known	missense	c.2427	p.K809N	1.000	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core	pfam_Andrgn_rcpt,pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Andrgn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	AR	HGNC	ENSG00000169083	tier1	-	-	51	0	0.00	7	20	74.07
ASTN1	0	genome.wustl.edu	37	1	177001858	177001858	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	177001858	177001858	T	C	SNP	ASTN1	ENST00000367654	human	ensembl	74_37	-1	known	missense	c.599	p.E200G	1.000	NULL	superfamily_Fibronectin_type3,smart_EG-like_dom,smart_MACPF,pfscan_Fibronectin_type3	-	no_errors	ASTN1	HGNC	ENSG00000152092	tier1	-	-	63	0	0.00	25	18	41.86
ASXL1	0	genome.wustl.edu	37	20	31019407	31019407	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	20	31019407	31019407	C	T	SNP	ASXL1	ENST00000375687	human	ensembl	74_37	+1	known	missense	c.904	p.R302C	1.000	NULL	NULL	-	no_errors	ASXL1	HGNC	ENSG00000171456	tier1	-	-	86	0	0.00	30	17	36.17
ATP13A5	0	genome.wustl.edu	37	3	193042674	193042674	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	193042674	193042674	T	C	SNP	ATP13A5	ENST00000342358	human	ensembl	74_37	-1	known	silent	c.1653	p.K551	0.997	superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,tigrfam_ATPase_P-typ_Cation_typ_V	pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_Cation_typ_V,pfam_ATPase_P-typ_cation-transptr_N,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Cation_typ_V,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP13A5	HGNC	ENSG00000187527	tier1	-	-	354	0	0.00	88	116	56.86
AVPR2	0	genome.wustl.edu	37	X	153170624	153170624	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	153170624	153170624	G	A	SNP	AVPR2	ENST00000337474	human	ensembl	74_37	+1	known	missense	c.25	p.A9T	0.232	prints_Vprsn_rcpt_V2	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Vprsn_rcpt_V2,prints_Vasoprsn_rcpt,prints_GPCR_Rhodpsn	-	no_errors	AVPR2	HGNC	ENSG00000126895	tier1	-	-	86	0	0.00	3	28	90.32
BAGE2	0	genome.wustl.edu	37	21	11047501	11047501	+	RNA	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	21	11047501	11047501	T	G	SNP	BAGE2	ENST00000470054	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	BAGE2	HGNC	ENSG00000187172	tier1	-	-	408	0	0.00	208	21	9.17
BAI3	0	genome.wustl.edu	37	6	69759213	69759213	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	69759213	69759213	T	G	SNP	BAI3	ENST00000370598	human	ensembl	74_37	+1	known	missense	c.2308	p.L770V	1.000	pfam_DUF3497	pfam_GPCR_2_secretin-like,pfam_DUF3497,pfam_Thrombospondin_1_rpt,pfam_GPS_dom,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_GPCR_2_extracellular_dom,smart_GPS_dom,pfscan_CUB_dom,pfscan_GPS_dom,pfscan_Thrombospondin_1_rpt,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_brain-spec_angio_inhib,prints_GPCR_2_secretin-like	-	no_errors	BAI3	HGNC	ENSG00000135298	tier1	-	-	199	0	0.00	77	52	40.31
BCL11A	0	genome.wustl.edu	37	2	60688785	60688785	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	60688785	60688785	T	C	SNP	BCL11A	ENST00000335712	human	ensembl	74_37	-1	known	missense	c.1262	p.K421R	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	BCL11A	HGNC	ENSG00000119866	tier1	-	-	120	0	0.00	68	34	33.01
BRD1	0	genome.wustl.edu	37	22	50187718	50187718	+	Frame_Shift_Del	DEL	C	C	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	22	50187718	50187718	C	-	DEL	BRD1	ENST00000216267	human	ensembl	74_37	-1	known	frame_shift_del	c.2323	p.D775fs	1.000	NULL	pfam_Enhancer_polycomb-like_N,pfam_Bromodomain,pfam_PWWP_dom,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_Bromodomain,smart_PWWP_dom,prints_Bromodomain,pfscan_PWWP_dom,pfscan_Znf_PHD-finger,pfscan_Bromodomain	-	no_errors	BRD1	HGNC	ENSG00000100425	tier1			61	0	0.00	13	2	13.33
C12orf43	0	genome.wustl.edu	37	12	121448813	121448813	+	Splice_Site	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	121448813	121448813	C	T	SNP	C12orf43	ENST00000539088	human	ensembl	74_37	-1	known	splice_site	c.180+1	e2+1	0.000	-	-	-	no_errors	C12orf43	HGNC	ENSG00000157895	tier1	-	-	79	0	0.00	11	24	68.57
C16orf71	0	genome.wustl.edu	37	16	4790603	4790603	+	Silent	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	4790603	4790603	C	A	SNP	C16orf71	ENST00000299320	human	ensembl	74_37	+1	known	silent	c.726	p.P242	0.001	NULL	NULL	-	no_errors	C16orf71	HGNC	ENSG00000166246	tier1	-	-	51	0	0.00	22	11	33.33
C1orf173	0	genome.wustl.edu	37	1	75038277	75038277	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	75038277	75038277	T	G	SNP	C1orf173	ENST00000326665	human	ensembl	74_37	-1	known	missense	c.3117	p.E1039D	0.003	NULL	NULL	-	no_errors	C1orf173	HGNC	ENSG00000178965	tier1	-	-	239	0	0.00	74	43	36.75
C1orf94	0	genome.wustl.edu	37	1	34663068	34663068	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	34663068	34663068	A	C	SNP	C1orf94	ENST00000488417	human	ensembl	74_37	+1	known	missense	c.563	p.K188T	1.000	NULL	NULL	-	no_errors	C1orf94	HGNC	ENSG00000142698	tier1	-	-	83	0	0.00	31	12	27.91
C8A	0	genome.wustl.edu	37	1	57347303	57347303	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	57347303	57347303	T	A	SNP	C8A	ENST00000361249	human	ensembl	74_37	+1	known	missense	c.650	p.F217Y	1.000	NULL	pfam_MACPF,pfam_LDrepeatLR_classA_rpt,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,superfamily_LDrepeatLR_classA_rpt,smart_Thrombospondin_1_rpt,smart_LDrepeatLR_classA_rpt,smart_MACPF,pfscan_LDrepeatLR_classA_rpt,pfscan_Thrombospondin_1_rpt,prints_MAC_perforin	-	no_errors	C8A	HGNC	ENSG00000157131	tier1	-	-	107	0	0.00	37	18	32.73
CCDC102B	0	genome.wustl.edu	37	18	66721373	66721373	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	66721373	66721373	A	-	DEL	CCDC102B	ENST00000319445	human	ensembl	74_37	+1	known	frame_shift_del	c.1541	p.*514fs	0.967	NULL	NULL	-	no_errors	CCDC102B	HGNC	ENSG00000150636	tier1			130	0	0.00	25	30	54.55
CCDC102B	0	genome.wustl.edu	37	18	66721374	66721374	+	Nonstop_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	66721374	66721374	A	C	SNP	CCDC102B	ENST00000319445	human	ensembl	74_37	+1	known	nonstop	c.1542	p.*514Y	0.970	NULL	NULL	-	no_errors	CCDC102B	HGNC	ENSG00000150636	tier1	-	-	131	0	0.00	50	5	9.09
CCDC135	0	genome.wustl.edu	37	16	57752258	57752258	+	Splice_Site	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	57752258	57752258	G	T	SNP	CCDC135	ENST00000360716	human	ensembl	74_37	+1	known	splice_site	c.1078-1	e7-1	1.000	-	-	-	no_errors	CCDC135	HGNC	ENSG00000159625	tier1	-	-	126	0	0.00	57	30	34.48
CCDC148	0	genome.wustl.edu	37	2	159077216	159077217	+	Frame_Shift_Ins	INS	-	-	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	159077216	159077217	-	T	INS	CCDC148	ENST00000283233	human	ensembl	74_37	-1	known	frame_shift_ins	c.1261_1260	p.Y420fs	1.000:1.000	NULL	NULL	-	no_errors	CCDC148	HGNC	ENSG00000153237	tier1			61	0	0.00	29	15	34.09
CCNA1	0	genome.wustl.edu	37	13	37007269	37007269	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	37007269	37007269	A	C	SNP	CCNA1	ENST00000255465	human	ensembl	74_37	+1	known	missense	c.208	p.T70P	0.617	pirsf_Cyclin_A/B/D/E	pfam_Cyclin_N,pfam_Cyclin_C-dom,superfamily_Cyclin-like,smart_Cyclin-like,pirsf_Cyclin_A/B/D/E	-	no_errors	CCNA1	HGNC	ENSG00000133101	tier1	-	-	45	0	0.00	13	8	38.10
CD1A	0	genome.wustl.edu	37	1	158225038	158225038	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	158225038	158225038	T	G	SNP	CD1A	ENST00000289429	human	ensembl	74_37	+1	known	missense	c.223	p.F75V	0.335	pfam_MHC_I_a_a1/a2,superfamily_MHC_I/II-like_Ag-recog	pfam_Ig_C1-set,pfam_MHC_I_a_a1/a2,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	CD1A	HGNC	ENSG00000158477	tier1	-	-	82	0	0.00	44	55	55.56
CD1E	0	genome.wustl.edu	37	1	158325192	158325192	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	158325192	158325192	T	C	SNP	CD1E	ENST00000368167	human	ensembl	74_37	+1	known	missense	c.458	p.I153T	0.468	superfamily_MHC_I/II-like_Ag-recog	pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	CD1E	HGNC	ENSG00000158488	tier1	-	-	158	0	0.00	64	64	50.00
CD99L2	0	genome.wustl.edu	37	X	149945928	149945928	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	149945928	149945928	T	C	SNP	CD99L2	ENST00000370377	human	ensembl	74_37	-1	known	missense	c.524	p.D175G	0.032	pfam_CD99L2	pfam_CD99L2	-	no_errors	CD99L2	HGNC	ENSG00000102181	tier1	-	-	58	0	0.00	2	32	94.12
CDC20	0	genome.wustl.edu	37	1	43824929	43824929	+	Nonsense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	43824929	43824929	C	T	SNP	CDC20	ENST00000310955	human	ensembl	74_37	+1	known	nonsense	c.43	p.Q15*	0.999	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	CDC20	HGNC	ENSG00000117399	tier1	-	-	116	0	0.00	30	27	47.37
CDH2	0	genome.wustl.edu	37	18	25593870	25593870	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	25593870	25593870	T	G	SNP	CDH2	ENST00000269141	human	ensembl	74_37	-1	known	missense	c.176	p.K59T	0.869	pfam_Cadherin_pro_dom,superfamily_Cadherin-like	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,pfam_Cadherin_pro_dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin,prints_Cadherin/Desmocollin	-	no_errors	CDH2	HGNC	ENSG00000170558	tier1	-	-	65	0	0.00	10	25	71.43
CDH8	0	genome.wustl.edu	37	16	61851463	61851463	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	61851463	61851463	T	G	SNP	CDH8	ENST00000577390	human	ensembl	74_37	-1	known	missense	c.1197	p.E399D	0.998	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH8	HGNC	ENSG00000150394	tier1	-	-	97	0	0.00	46	42	47.73
CDKN2A	0	genome.wustl.edu	37	9	21974780	21974780	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	21974780	21974780	A	C	SNP	CDKN2A	ENST00000446177	human	ensembl	74_37	-1	known	missense	c.47	p.L16R	0.068	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	CDKN2A	HGNC	ENSG00000147889	tier1	-	-	42	0	0.00	5	9	64.29
CHD1	0	genome.wustl.edu	37	5	98223914	98223914	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	98223914	98223914	G	T	SNP	CHD1	ENST00000284049	human	ensembl	74_37	-1	known	missense	c.2374	p.L792I	1.000	superfamily_P-loop_NTPase,pfscan_Helicase_C	pfam_SNF2_N,pfam_Chromo_domain,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,superfamily_Homeodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow	-	no_errors	CHD1	HGNC	ENSG00000153922	tier1	-	-	77	0	0.00	31	12	27.91
CHERP	0	genome.wustl.edu	37	19	16640581	16640583	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	TGC	TGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	16640581	16640583	TGC	-	DEL	CHERP	ENST00000546361	human	ensembl	74_37	-1	known	in_frame_del	c.1007_1005	p.Q339in_frame_del	1.000:1.000:1.000	NULL	pfam_Surp,pfam_G_patch_dom,pfam_RNA_pol_II-bd,superfamily_Surp,superfamily_ENTH_VHS,smart_Surp,smart_G_patch_dom,pfscan_Surp,pfscan_G_patch_dom	-	no_errors	CHERP	HGNC	ENSG00000085872	tier1			51	0	0.00	18	2	10.00
CLMP	0	genome.wustl.edu	37	11	122955249	122955249	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	122955249	122955249	A	C	SNP	CLMP	ENST00000448775	human	ensembl	74_37	-1	known	missense	c.359	p.V120G	0.998	pfam_Ig_V-set,pfam_Ig_I-set,pfam_CD47_Vset,smart_Ig_sub	pfam_Ig_V-set,pfam_Ig_I-set,pfam_CD47_Vset,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	CLMP	HGNC	ENSG00000166250	tier1	-	-	91	0	0.00	23	21	47.73
CLOCK	0	genome.wustl.edu	37	4	56304530	56304532	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	CTG	CTG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	56304530	56304532	CTG	-	DEL	CLOCK	ENST00000309964	human	ensembl	74_37	-1	known	in_frame_del	c.2280_2278	p.Q760in_frame_del	0.944:0.945:1.000	NULL	pfam_PAS_fold_3,pfam_PAS_fold,pfam_bHLH_dom,superfamily_PAS,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,smart_PAC,pfscan_PAS,pfscan_bHLH_dom,prints_Nuc_translocat	-	no_errors	CLOCK	HGNC	ENSG00000134852	tier1			76	0	0.00	38	4	9.52
CNR1	0	genome.wustl.edu	37	6	88854841	88854841	+	Silent	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	88854841	88854841	A	C	SNP	CNR1	ENST00000369499	human	ensembl	74_37	-1	known	silent	c.153	p.T51	0.894	pirsf_Canbinoid_rcpt_1,prints_Canbinoid_rcpt_1	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pirsf_Canbinoid_rcpt_1,pfscan_GPCR_Rhodpsn_7TM,prints_Canbinoid_rcpt_1,prints_Cnbnoid_rcpt,prints_GPCR_Rhodpsn	-	no_errors	CNR1	HGNC	ENSG00000118432	tier1	-	-	88	0	0.00	36	20	35.71
CNTLN	0	genome.wustl.edu	37	9	17330742	17330742	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	17330742	17330742	A	C	SNP	CNTLN	ENST00000380647	human	ensembl	74_37	+1	known	missense	c.1454	p.N485T	0.400	NULL	superfamily_Prefoldin	-	no_errors	CNTLN	HGNC	ENSG00000044459	tier1	-	-	187	0	0.00	17	37	68.52
CNTLN	0	genome.wustl.edu	37	9	17466793	17466793	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	17466793	17466793	A	G	SNP	CNTLN	ENST00000380647	human	ensembl	74_37	+1	known	silent	c.3759	p.Q1253	0.636	NULL	superfamily_Prefoldin	-	no_errors	CNTLN	HGNC	ENSG00000044459	tier1	-	-	103	0	0.00	9	39	81.25
COL24A1	0	genome.wustl.edu	37	1	86590793	86590793	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	86590793	86590793	T	G	SNP	COL24A1	ENST00000370571	human	ensembl	74_37	-1	known	missense	c.1226	p.K409T	0.980	NULL	pfam_Collagen,pfam_Fib_collagen_C,pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_Fib_collagen_C	-	no_errors	COL24A1	HGNC	ENSG00000171502	tier1	-	-	106	0	0.00	32	38	54.29
COL8A1	0	genome.wustl.edu	37	3	99514931	99514931	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	99514931	99514931	G	A	SNP	COL8A1	ENST00000261037	human	ensembl	74_37	+1	known	missense	c.2186	p.G729E	1.000	pfam_C1q,superfamily_Tumour_necrosis_fac-like_dom,smart_C1q,pfscan_C1q	pfam_Collagen,pfam_C1q,superfamily_Tumour_necrosis_fac-like_dom,smart_C1q,pfscan_C1q,prints_C1q	-	no_errors	COL8A1	HGNC	ENSG00000144810	tier1	-	-	69	0	0.00	12	15	55.56
CPXCR1	0	genome.wustl.edu	37	X	88008469	88008469	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	88008469	88008469	T	G	SNP	CPXCR1	ENST00000276127	human	ensembl	74_37	+1	known	missense	c.54	p.N18K	0.082	NULL	pfscan_Znf_C2H2	-	no_errors	CPXCR1	HGNC	ENSG00000147183	tier1	-	-	17	0	0.00	6	11	64.71
CREBBP	0	genome.wustl.edu	37	16	3900421	3900421	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	3900421	3900421	C	T	SNP	CREBBP	ENST00000262367	human	ensembl	74_37	-1	known	silent	c.675	p.P225	0.547	NULL	pfam_Histone_H3-K56_AcTrfase_RTT109,pfam_Nuc_rcpt_coact_CREBbp,pfam_KIX_dom,pfam_DUF902_CREBbp,pfam_Znf_TAZ,pfam_Bromodomain,pfam_Znf_ZZ,superfamily_Bromodomain,superfamily_Znf_TAZ,superfamily_KIX_dom,superfamily_Nuc_rcpt_coact,superfamily_Znf_FYVE_PHD,smart_Znf_TAZ,smart_Bromodomain,smart_Znf_ZZ,pfscan_KIX_dom,pfscan_Znf_TAZ,pfscan_Znf_ZZ,pfscan_Bromodomain,prints_Bromodomain	-	no_errors	CREBBP	HGNC	ENSG00000005339	tier1	rs140708841	-	79	0	0.00	39	12	23.53
CSMD1	0	genome.wustl.edu	37	8	3253866	3253866	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	3253866	3253866	T	C	SNP	CSMD1	ENST00000520002	human	ensembl	74_37	-1	known	missense	c.2446	p.R816G	0.001	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD1	HGNC	ENSG00000183117	tier1	-	-	18	0	0.00	8	4	33.33
CSMD3	0	genome.wustl.edu	37	8	113347666	113347666	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	113347666	113347666	A	C	SNP	CSMD3	ENST00000297405	human	ensembl	74_37	-1	known	missense	c.7057	p.F2353V	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD3	HGNC	ENSG00000164796	tier1	-	-	76	0	0.00	30	30	50.00
CTNNA3	0	genome.wustl.edu	37	10	67726416	67726416	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	67726416	67726416	A	C	SNP	CTNNA3	ENST00000373744	human	ensembl	74_37	-1	known	missense	c.2354	p.V785G	0.995	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	pfam_Vinculin/catenin,superfamily_Vinculin/catenin,prints_Alpha_catenin,prints_Vinculin	-	no_errors	CTNNA3	HGNC	ENSG00000183230	tier1	-	-	107	0	0.00	32	27	45.76
CTNND1	0	genome.wustl.edu	37	11	57575764	57575764	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	57575764	57575764	G	A	SNP	CTNND1	ENST00000399050	human	ensembl	74_37	+1	known	silent	c.2091	p.T697	0.935	superfamily_ARM-type_fold	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	CTNND1	HGNC	ENSG00000198561	tier1	-	-	78	0	0.00	39	8	17.02
CUX2	0	genome.wustl.edu	37	12	111652028	111652028	+	Missense_Mutation	SNP	G	G	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	111652028	111652028	G	C	SNP	CUX2	ENST00000261726	human	ensembl	74_37	+1	known	missense	c.88	p.E30Q	0.994	NULL	pfam_Hmoeo_CUT,pfam_Homeobox_dom,superfamily_Lambda_DNA-bd_dom,superfamily_Homeodomain-like,superfamily_Prefoldin,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Hmoeo_CUT	-	no_errors	CUX2	HGNC	ENSG00000111249	tier1	-	-	127	0	0.00	15	42	73.68
DCC	0	genome.wustl.edu	37	18	50866130	50866130	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	50866130	50866130	A	G	SNP	DCC	ENST00000442544	human	ensembl	74_37	+1	known	missense	c.2212	p.T738A	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Neogenin_C,pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DCC	HGNC	ENSG00000187323	tier1	-	-	155	0	0.00	17	48	73.85
DCHS2	0	genome.wustl.edu	37	4	155180831	155180831	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	155180831	155180831	T	G	SNP	DCHS2	ENST00000357232	human	ensembl	74_37	-1	known	missense	c.5290	p.S1764R	0.560	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_HTH_CenpB_DNA-bd_dom,superfamily_Cadherin-like,superfamily_Homeodomain-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS2	HGNC	ENSG00000197410	tier1	-	-	106	0	0.00	49	22	30.56
DCHS2	0	genome.wustl.edu	37	4	155254023	155254023	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	155254023	155254023	G	A	SNP	DCHS2	ENST00000357232	human	ensembl	74_37	-1	known	missense	c.1840	p.P614S	0.009	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_HTH_CenpB_DNA-bd_dom,superfamily_Cadherin-like,superfamily_Homeodomain-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS2	HGNC	ENSG00000197410	tier1	-	-	61	0	0.00	23	24	50.00
DCHS2	0	genome.wustl.edu	37	4	155254615	155254615	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	155254615	155254615	A	G	SNP	DCHS2	ENST00000357232	human	ensembl	74_37	-1	known	silent	c.1248	p.S416	0.990	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_HTH_CenpB_DNA-bd_dom,superfamily_Cadherin-like,superfamily_Homeodomain-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	DCHS2	HGNC	ENSG00000197410	tier1	-	-	41	0	0.00	15	11	42.31
DCLK1	0	genome.wustl.edu	37	13	36385071	36385071	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	36385071	36385071	T	G	SNP	DCLK1	ENST00000360631	human	ensembl	74_37	-1	known	missense	c.1589	p.K530T	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Doublecortin_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Doublecortin_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Doublecortin_dom,pfscan_Prot_kinase_dom	-	no_errors	DCLK1	HGNC	ENSG00000133083	tier1	-	-	179	0	0.00	64	53	45.30
DCLK1	0	genome.wustl.edu	37	13	36521572	36521572	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	36521572	36521572	A	C	SNP	DCLK1	ENST00000360631	human	ensembl	74_37	-1	known	missense	c.746	p.F249C	1.000	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	pfam_Prot_kinase_dom,pfam_Doublecortin_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Doublecortin_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Doublecortin_dom,pfscan_Prot_kinase_dom	-	no_errors	DCLK1	HGNC	ENSG00000133083	tier1	-	-	60	0	0.00	10	23	69.70
DCSTAMP	0	genome.wustl.edu	37	8	105367380	105367380	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	105367380	105367380	A	C	SNP	DCSTAMP	ENST00000297581	human	ensembl	74_37	+1	known	missense	c.1305	p.E435D	0.000	superfamily_ABC1_TM_dom	pfam_DC_STAMP-like,superfamily_ABC1_TM_dom	-	no_errors	DCSTAMP	HGNC	ENSG00000164935	tier1	-	-	103	0	0.00	55	45	45.00
DDX60L	0	genome.wustl.edu	37	4	169344916	169344916	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	169344916	169344916	G	A	SNP	DDX60L	ENST00000260184	human	ensembl	74_37	-1	known	missense	c.1940	p.S647L	0.270	NULL	pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DDX60L	HGNC	ENSG00000181381	tier1	-	-	28	0	0.00	9	6	40.00
DIDO1	0	genome.wustl.edu	37	20	61537401	61537402	+	Frame_Shift_Ins	INS	-	-	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	20	61537401	61537402	-	T	INS	DIDO1	ENST00000266070	human	ensembl	74_37	-1	known	frame_shift_ins	c.1426_1425	p.E475fs	1.000:0.986	NULL	pfam_TFIIS_cen_dom,pfam_SPOC_C,pfam_Znf_PHD-finger,superfamily_TFIIS_cen_dom,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_TFS2M,pfscan_Znf_PHD-finger	-	no_errors	DIDO1	HGNC	ENSG00000101191	tier1			160	0	0.00	68	14	17.07
DNAAF1	0	genome.wustl.edu	37	16	84182639	84182639	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	84182639	84182639	T	C	SNP	DNAAF1	ENST00000378553	human	ensembl	74_37	+1	known	missense	c.152	p.V51A	0.000	NULL	NULL	-	no_errors	DNAAF1	HGNC	ENSG00000154099	tier1	-	-	87	0	0.00	40	22	35.48
DNAAF1	0	genome.wustl.edu	37	16	84193342	84193342	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	84193342	84193342	C	T	SNP	DNAAF1	ENST00000378553	human	ensembl	74_37	+1	known	silent	c.804	p.V268	0.998	NULL	NULL	-	no_errors	DNAAF1	HGNC	ENSG00000154099	tier1	-	-	61	0	0.00	28	10	26.32
DNAH10	0	genome.wustl.edu	37	12	124403316	124403316	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	124403316	124403316	C	T	SNP	DNAH10	ENST00000409039	human	ensembl	74_37	+1	known	silent	c.10972	p.L3658	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_PyrdxlP-dep_Trfase,smart_AAA+_ATPase	-	no_errors	DNAH10	HGNC	ENSG00000197653	tier1	-	-	44	0	0.00	3	15	83.33
DNAH11	0	genome.wustl.edu	37	7	21721205	21721205	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	21721205	21721205	A	C	SNP	DNAH11	ENST00000328843	human	ensembl	74_37	+1	known	missense	c.5385	p.E1795D	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH11	HGNC	ENSG00000105877	tier1	-	-	56	0	0.00	45	22	32.84
DNAH8	0	genome.wustl.edu	37	6	38867568	38867568	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	38867568	38867568	G	A	SNP	DNAH8	ENST00000359357	human	ensembl	74_37	+1	known	missense	c.8429	p.R2810Q	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH8	HGNC	ENSG00000124721	tier1	-	-	85	0	0.00	29	18	38.30
DPAGT1	0	genome.wustl.edu	37	11	118968667	118968667	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	118968667	118968667	C	T	SNP	DPAGT1	ENST00000354202	human	ensembl	74_37	-1	known	missense	c.815	p.S272N	1.000	NULL	pfam_Glycosyl_transferase_4	-	no_errors	DPAGT1	HGNC	ENSG00000172269	tier1	-	-	121	0	0.00	42	25	37.31
DPP10	0	genome.wustl.edu	37	2	116548879	116548879	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	116548879	116548879	G	T	SNP	DPP10	ENST00000393147	human	ensembl	74_37	+1	known	missense	c.1659	p.L553F	1.000	NULL	pfam_Peptidase_S9B,pfam_Peptidase_S9	-	no_errors	DPP10	HGNC	ENSG00000175497	tier1	-	-	346	0	0.00	126	55	30.39
DST	0	genome.wustl.edu	37	6	56437652	56437652	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	56437652	56437652	C	T	SNP	DST	ENST00000370754	human	ensembl	74_37	-1	known	missense	c.13354	p.E4452K	1.000	superfamily_ABC1_TM_dom	pfam_Spectrin_repeat,pfam_Plectin_repeat,pfam_CH-domain,pfam_GAS2_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_GAS2_dom,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Plectin_repeat,smart_EF_hand_dom,smart_GAS2_dom,pfscan_CH-domain,pfscan_EF_hand_dom	-	no_errors	DST	HGNC	ENSG00000151914	tier1	-	-	33	0	0.00	15	13	46.43
DYNC2H1	0	genome.wustl.edu	37	11	103039508	103039508	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	103039508	103039508	T	G	SNP	DYNC2H1	ENST00000398093	human	ensembl	74_37	+1	known	missense	c.4787	p.L1596R	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DYNC2H1	HGNC	ENSG00000187240	tier1	-	-	93	0	0.00	36	13	26.53
EBF1	0	genome.wustl.edu	37	5	158141188	158141188	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	158141188	158141188	T	G	SNP	EBF1	ENST00000313708	human	ensembl	74_37	-1	known	missense	c.1128	p.E376D	1.000	superfamily_bHLH_dom	pfam_IPT,superfamily_Ig_E-set,superfamily_bHLH_dom,smart_IPT	-	no_errors	EBF1	HGNC	ENSG00000164330	tier1	-	-	200	0	0.00	83	28	25.23
EML1	0	genome.wustl.edu	37	14	100361038	100361038	+	Missense_Mutation	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	100361038	100361038	C	A	SNP	EML1	ENST00000334192	human	ensembl	74_37	+1	known	missense	c.677	p.S226Y	0.881	pfam_HELP	pfam_HELP,pfam_WD40_repeat,superfamily_Quinonprotein_ADH-like_supfam,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	EML1	HGNC	ENSG00000066629	tier1	-	-	83	0	0.00	35	21	37.50
ENTPD2	0	genome.wustl.edu	37	9	139944978	139944978	+	Frame_Shift_Del	DEL	G	G	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	139944978	139944978	G	-	DEL	ENTPD2	ENST00000355097	human	ensembl	74_37	-1	known	frame_shift_del	c.787	p.H263fs	0.987	pfam_GDA1_CD39_NTPase	pfam_GDA1_CD39_NTPase	-	no_errors	ENTPD2	HGNC	ENSG00000054179	tier1			50	0	0.00	13	2	13.33
EPB41L3	0	genome.wustl.edu	37	18	5394733	5394733	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	5394733	5394733	T	G	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.3213	p.K1071N	1.000	pirsf_Band_41_protein,pfam_Band_4.1_C	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397	tier1	-	-	208	0	0.00	27	52	65.82
EPB41L3	0	genome.wustl.edu	37	18	5434011	5434011	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	5434011	5434011	C	T	SNP	EPB41L3	ENST00000341928	human	ensembl	74_37	-1	known	missense	c.715	p.D239N	1.000	pirsf_Band_41_protein,pfam_FERM_central,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam	pirsf_Band_41_protein,pfam_Band_4.1_C,pfam_SAB_dom,pfam_FERM_N,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM-adjacent,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	EPB41L3	HGNC	ENSG00000082397	tier1	-	-	182	0	0.00	16	61	79.22
ERBB4	0	genome.wustl.edu	37	2	212248596	212248596	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	212248596	212248596	T	G	SNP	ERBB4	ENST00000342788	human	ensembl	74_37	-1	known	missense	c.3671	p.N1224T	1.000	pirsf_Tyr_kinase_EGF/ERB/XmrK_rcpt	pirsf_Tyr_kinase_EGF/ERB/XmrK_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_EGF_rcpt_L,pfam_Prot_kinase_dom,pfam_Furin-like_Cys-rich_dom,superfamily_Kinase-like_dom,superfamily_Growth_fac_rcpt_N_dom,smart_Furin_repeat,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	ERBB4	HGNC	ENSG00000178568	tier1	-	-	215	0	0.00	80	40	33.33
EYS	0	genome.wustl.edu	37	6	66200494	66200494	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	66200494	66200494	T	G	SNP	EYS	ENST00000370616	human	ensembl	74_37	-1	known	missense	c.855	p.Q285H	0.000	smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	pfam_Laminin_G,pfam_EG-like_dom,superfamily_ConA-like_lec_gl_sf,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	EYS	HGNC	ENSG00000188107	tier1	-	-	41	0	0.00	21	7	25.00
FAM63B	0	genome.wustl.edu	37	15	59063682	59063682	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	59063682	59063682	C	T	SNP	FAM63B	ENST00000559228	human	ensembl	74_37	+1	known	silent	c.88	p.L30	0.001	NULL	pfam_DUF544	-	no_errors	FAM63B	HGNC	ENSG00000128923	tier1	-	-	61	0	0.00	23	5	17.86
FAM65C	0	genome.wustl.edu	37	20	49203764	49203765	+	RNA	INS	-	-	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	20	49203764	49203765	-	T	INS	FAM65C	ENST00000462842	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.000:0.005	-	-	-	no_errors	FAM65C	HGNC	ENSG00000042062	tier1			84	0	0.00	28	21	42.86
FASN	0	genome.wustl.edu	37	17	80041194	80041194	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	80041194	80041194	C	T	SNP	FASN	ENST00000306749	human	ensembl	74_37	-1	known	missense	c.5449	p.G1817S	1.000	smart_PKS_ER	pfam_Acyl_transferase,pfam_Ketoacyl_synth_N,pfam_Thioesterase,pfam_PKS_KR,pfam_DH_sc/Rdtase_SDR,pfam_Ketoacyl_synth_C,pfam_ADH_C,pfam_Acyl_carrier_prot-like,pfam_Methyltransf_12,pfam_Methyltransf_11,superfamily_Thiolase-like,superfamily_Acyl_Trfase/lysoPLipase,superfamily_GroES-like,superfamily_Acyl_carrier_prot-like,superfamily_Malonyl_transacylase_ACP-bd,smart_PKS_Beta-ketoAc_synthase_dom,smart_PKS_acyl_transferase,smart_PKS_dehydratase,smart_PKS_ER,smart_PKS/FAS_KR,smart_PKS_PP-bd,pfscan_Acyl_carrier_prot-like	-	no_errors	FASN	HGNC	ENSG00000169710				79	0	0.00	43	4	8.51
FAT3	0	genome.wustl.edu	37	11	92533395	92533395	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	92533395	92533395	T	G	SNP	FAT3	ENST00000298047	human	ensembl	74_37	+1	known	missense	c.7216	p.L2406V	0.882	pfam_Cadherin,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT3	HGNC	ENSG00000165323	tier1	-	-	206	0	0.00	61	35	36.46
FAT4	0	genome.wustl.edu	37	4	126372220	126372220	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	126372220	126372220	A	C	SNP	FAT4	ENST00000394329	human	ensembl	74_37	+1	known	missense	c.10049	p.K3350T	0.003	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT4	HGNC	ENSG00000196159	tier1	-	-	187	0	0.00	64	29	31.18
FAT4	0	genome.wustl.edu	37	4	126384743	126384743	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	126384743	126384743	T	G	SNP	FAT4	ENST00000394329	human	ensembl	74_37	+1	known	missense	c.11820	p.N3940K	1.000	smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT4	HGNC	ENSG00000196159	tier1	-	-	23	0	0.00	6	6	50.00
FBXO24	0	genome.wustl.edu	37	7	100193300	100193300	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	100193300	100193300	G	A	SNP	FBXO24	ENST00000427939	human	ensembl	74_37	+1	known	missense	c.1291	p.D431N	1.000	pfam_Reg_chr_condens,superfamily_RCC1/BLIP-II,pfscan_Reg_chr_condens	pfam_F-box_dom,pfam_Reg_chr_condens,superfamily_RCC1/BLIP-II,superfamily_F-box_dom,smart_F-box_dom,pfscan_F-box_dom,pfscan_Reg_chr_condens	-	no_errors	FBXO24	HGNC	ENSG00000106336	tier1	-	-	92	0	0.00	42	26	38.24
FMN2	0	genome.wustl.edu	37	1	240492410	240492410	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	240492410	240492410	A	G	SNP	FMN2	ENST00000319653	human	ensembl	74_37	+1	known	missense	c.4250	p.K1417R	1.000	pfam_FH2_Formin,smart_FH2_Formin	pfam_FH2_Formin,pfam_Formin_homology_1,smart_FH2_Formin,pfscan_DEP_dom	-	no_errors	FMN2	HGNC	ENSG00000155816	tier1	-	-	110	0	0.00	43	19	30.65
FSD2	0	genome.wustl.edu	37	15	83455922	83455922	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	83455922	83455922	A	C	SNP	FSD2	ENST00000334574	human	ensembl	74_37	-1	known	missense	c.221	p.L74R	0.038	NULL	pfam_Fibronectin_type3,pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Fibronectin_type3,prints_Butyrophylin	-	no_errors	FSD2	HGNC	ENSG00000186628	tier1	-	-	200	0	0.00	97	37	27.61
FSHR	0	genome.wustl.edu	37	2	49191063	49191063	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	49191063	49191063	T	G	SNP	FSHR	ENST00000406846	human	ensembl	74_37	-1	known	missense	c.897	p.Q299H	1.000	pfam_GnHR_TM,prints_FSH_rcpt	pfam_GPCR_Rhodpsn,pfam_GnHR_TM,pfam_LRR-contain_N,pfam_Leu-rich_rpt,smart_LRR-contain_N,pfscan_GPCR_Rhodpsn_7TM,prints_FSH_rcpt,prints_Gphrmn_rcpt_fam,prints_GPCR_Rhodpsn,prints_TSH_rcpt	-	no_errors	FSHR	HGNC	ENSG00000170820	tier1	-	-	296	0	0.00	98	85	46.45
GINS1	0	genome.wustl.edu	37	20	25398808	25398808	+	Nonsense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	20	25398808	25398808	C	T	SNP	GINS1	ENST00000262460	human	ensembl	74_37	+1	known	nonsense	c.307	p.R103*	0.774	NULL	NULL	-	no_errors	GINS1	HGNC	ENSG00000101003	tier1	-	-	92	0	0.00	47	21	30.88
GLRB	0	genome.wustl.edu	37	4	158041763	158041763	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	158041763	158041763	T	G	SNP	GLRB	ENST00000264428	human	ensembl	74_37	+1	known	missense	c.178	p.L60V	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,prints_Glycine_rcpt_B,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_Glycine_rcpt_B,prints_GABAA_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	GLRB	HGNC	ENSG00000109738	tier1	-	-	121	0	0.00	38	33	46.48
GOLIM4	0	genome.wustl.edu	37	3	167750505	167750505	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	167750505	167750505	G	A	SNP	GOLIM4	ENST00000470487	human	ensembl	74_37	-1	known	missense	c.979	p.R327C	0.000	NULL	NULL	-	no_errors	GOLIM4	HGNC	ENSG00000173905	tier1	-	-	80	0	0.00	33	39	54.17
GPC6	0	genome.wustl.edu	37	13	95055341	95055341	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	95055341	95055341	T	C	SNP	GPC6	ENST00000377047	human	ensembl	74_37	+1	known	missense	c.1538	p.V513A	1.000	pfam_Glypican	pfam_Glypican	-	no_errors	GPC6	HGNC	ENSG00000183098	tier1	-	-	72	0	0.00	35	35	50.00
GRM1	0	genome.wustl.edu	37	6	146480720	146480720	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	146480720	146480720	T	A	SNP	GRM1	ENST00000282753	human	ensembl	74_37	+1	known	missense	c.937	p.S313T	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_Metabotropic_Glu_rcpt_Homer-bd,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3_mtglu_rcpt_1,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_5	-	no_errors	GRM1	HGNC	ENSG00000152822	tier1	-	-	44	0	0.00	18	15	44.12
GRM3	0	genome.wustl.edu	37	7	86394541	86394541	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	86394541	86394541	A	C	SNP	GRM3	ENST00000361669	human	ensembl	74_37	+1	known	missense	c.80	p.N27T	1.000	prints_GPCR_3_mtglu_rcpt_3	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt_3,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_2,prints_GPCR_3_GABA_rcpt_B	-	no_errors	GRM3	HGNC	ENSG00000198822	tier1	-	-	147	0	0.00	79	46	36.80
GRM6	0	genome.wustl.edu	37	5	178410177	178410177	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	178410177	178410177	C	T	SNP	GRM6	ENST00000231188	human	ensembl	74_37	-1	known	missense	c.2170	p.V724M	0.940	pfam_GPCR_3_C,pfscan_GPCR_3_C	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt_6,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_4	-	no_errors	GRM6	HGNC	ENSG00000113262	tier1	rs151103990	-	84	0	0.00	18	11	37.93
GTF3C4	0	genome.wustl.edu	37	9	135546200	135546200	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	135546200	135546200	G	A	SNP	GTF3C4	ENST00000372146	human	ensembl	74_37	+1	known	nonsense	c.215	p.W72*	1.000	NULL	superfamily_WD40_repeat_dom	-	no_errors	GTF3C4	HGNC	ENSG00000125484	tier1	-	-	16	0	0.00	4	5	55.56
HFM1	0	genome.wustl.edu	37	1	91817108	91817108	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	91817108	91817108	G	A	SNP	HFM1	ENST00000370425	human	ensembl	74_37	-1	known	silent	c.2070	p.S690	1.000	pfscan_Helicase_C	pfam_Sec63-dom,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Sec63-dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	HFM1	HGNC	ENSG00000162669	tier1	-	-	130	0	0.00	45	24	34.78
HIVEP1	0	genome.wustl.edu	37	6	12122176	12122176	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	12122176	12122176	G	A	SNP	HIVEP1	ENST00000379388	human	ensembl	74_37	+1	known	silent	c.2148	p.T716	0.007	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	HIVEP1	HGNC	ENSG00000095951	tier1	-	-	63	0	0.00	15	12	44.44
HRNR	0	genome.wustl.edu	37	1	152191994	152191994	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	152191994	152191994	T	G	SNP	HRNR	ENST00000368801	human	ensembl	74_37	-1	known	missense	c.2111	p.K704T	0.000	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom	-	no_errors	HRNR	HGNC	ENSG00000197915	tier1	-	-	398	0	0.00	256	126	32.98
HYAL2	0	genome.wustl.edu	37	3	50357676	50357676	+	Frame_Shift_Del	DEL	C	C	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	50357676	50357676	C	-	DEL	HYAL2	ENST00000357750	human	ensembl	74_37	-1	known	frame_shift_del	c.245	p.R82fs	0.996	pfam_Hyaluronidase,superfamily_Glycoside_hydrolase_SF,pirsf_Hyaluronidase	pfam_Hyaluronidase,superfamily_Glycoside_hydrolase_SF,pirsf_Hyaluronidase,prints_Hyaluronidase	-	no_errors	HYAL2	HGNC	ENSG00000068001	tier1			63	0	0.00	17	2	10.53
IAPP	0	genome.wustl.edu	37	12	21526294	21526294	+	Missense_Mutation	SNP	C	C	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	21526294	21526294	C	G	SNP	IAPP	ENST00000240652	human	ensembl	74_37	+1	known	missense	c.9	p.I3M	0.000	prints_Pro-islet_amyloid_polypep	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Pro-islet_amyloid_polypep	-	no_errors	IAPP	HGNC	ENSG00000121351	tier1	-	-	108	0	0.00	157	10	5.95
IAPP	0	genome.wustl.edu	37	12	21526343	21526343	+	Missense_Mutation	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	21526343	21526343	C	A	SNP	IAPP	ENST00000240652	human	ensembl	74_37	+1	known	missense	c.58	p.L20M	0.459	prints_Pro-islet_amyloid_polypep	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Pro-islet_amyloid_polypep	-	no_errors	IAPP	HGNC	ENSG00000121351	tier1	-	-	139	0	0.00	186	10	5.10
IAPP	0	genome.wustl.edu	37	12	21526313	21526313	+	Frame_Shift_Del	DEL	C	C	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	21526313	21526313	C	0	DEL	IAPP	ENST00000240652	human	ensembl	74_37	+1	known	frame_shift_del	c.28	p.L10fs	0.004	prints_Pro-islet_amyloid_polypep	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Pro-islet_amyloid_polypep	-	no_errors	IAPP	HGNC	ENSG00000121351				137	0	0.00	174	10	5.43
IAPP	0	genome.wustl.edu	37	12	21526326	21526326	+	Missense_Mutation	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	21526326	21526326	C	A	SNP	IAPP	ENST00000240652	human	ensembl	74_37	+1	known	missense	c.41	p.S14Y	0.568	prints_Pro-islet_amyloid_polypep	pfam_Procalcitonin/adrenomedullin,smart_Calcitonin_peptide-like,prints_Pro-islet_amyloid_polypep	-	no_errors	IAPP	HGNC	ENSG00000121351				138	0	0.00	183	11	5.67
IL12A	0	genome.wustl.edu	37	3	159713299	159713299	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	159713299	159713299	C	T	SNP	IL12A	ENST00000305579	human	ensembl	74_37	+1	known	missense	c.715	p.R239W	0.533	pfam_IL-12_alpha,superfamily_4_helix_cytokine-like_core	pfam_IL-12_alpha,superfamily_4_helix_cytokine-like_core	-	no_errors	IL12A	HGNC	ENSG00000168811	tier1	-	-	181	0	0.00	41	42	50.60
INF2	0	genome.wustl.edu	37	14	105177496	105177496	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	105177496	105177496	C	T	SNP	INF2	ENST00000392634	human	ensembl	74_37	+1	known	silent	c.2391	p.R797	0.015	pfam_FH2_Formin,smart_FH2_Formin	pfam_FH2_Formin,pfam_FH3_dom,pfam_GTPase-bd,pfam_WH2_dom,superfamily_ARM-type_fold,smart_FH2_Formin,pfscan_WH2_dom	-	no_errors	INF2	HGNC	ENSG00000203485				16	0	0.00	6	3	33.33
IRX6	0	genome.wustl.edu	37	16	55363131	55363131	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	55363131	55363131	A	C	SNP	IRX6	ENST00000290552	human	ensembl	74_37	+1	known	missense	c.1241	p.K414T	0.009	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,smart_Iroquois_homeo,pfscan_Homeobox_dom	-	no_errors	IRX6	HGNC	ENSG00000159387	tier1	-	-	100	0	0.00	24	19	44.19
ITIH5	0	genome.wustl.edu	37	10	7611540	7611540	+	RNA	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	7611540	7611540	T	G	SNP	ITIH5	ENST00000492668	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	ITIH5	HGNC	ENSG00000123243	tier1	-	-	17	0	0.00	4	7	63.64
ITPRIP	0	genome.wustl.edu	37	10	106074373	106074373	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	106074373	106074373	G	A	SNP	ITPRIP	ENST00000278071	human	ensembl	74_37	-1	known	silent	c.1437	p.I479	0.463	NULL	NULL	-	no_errors	ITPRIP	HGNC	ENSG00000148841	tier1	-	-	162	0	0.00	67	7	9.46
KCNT1	0	genome.wustl.edu	37	9	138651550	138651550	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	138651550	138651550	C	T	SNP	KCNT1	ENST00000298480	human	ensembl	74_37	+1	known	missense	c.880	p.R294W	1.000	pfam_2pore_dom_K_chnl_dom	pfam_K_chnl_Ca-activ_BK_asu,pfam_2pore_dom_K_chnl_dom	-	no_errors	KCNT1	HGNC	ENSG00000107147	tier1	-	-	83	0	0.00	24	16	40.00
KHDRBS2	0	genome.wustl.edu	37	6	62442600	62442600	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	62442600	62442600	T	C	SNP	KHDRBS2	ENST00000281156	human	ensembl	74_37	-1	known	missense	c.880	p.T294A	0.744	NULL	pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1	-	no_errors	KHDRBS2	HGNC	ENSG00000112232	tier1	rs146475584	-	111	0	0.00	36	35	49.30
KIAA0226L	0	genome.wustl.edu	37	13	46917551	46917551	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	46917551	46917551	A	C	SNP	KIAA0226L	ENST00000389908	human	ensembl	74_37	-1	known	missense	c.1958	p.L653R	0.147	NULL	NULL	-	no_errors	KIAA0226L	HGNC	ENSG00000102445	tier1	-	-	65	0	0.00	29	13	30.95
KIF18B	0	genome.wustl.edu	37	17	43011663	43011663	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	43011663	43011663	C	T	SNP	KIF18B	ENST00000339151	human	ensembl	74_37	-1	known	missense	c.823	p.A275T	0.998	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF18B	HGNC	ENSG00000186185	tier1	-	-	32	0	0.00	15	4	21.05
KIF2B	0	genome.wustl.edu	37	17	51901630	51901630	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	51901630	51901630	T	G	SNP	KIF2B	ENST00000268919	human	ensembl	74_37	+1	known	silent	c.1236	p.T412	0.998	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF2B	HGNC	ENSG00000141200	tier1	-	-	91	0	0.00	39	23	37.10
KLHL4	0	genome.wustl.edu	37	X	86887246	86887246	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	86887246	86887246	A	C	SNP	KLHL4	ENST00000373114	human	ensembl	74_37	+1	known	missense	c.1361	p.N454T	1.000	pfam_Kelch_1,smart_Kelch_1	pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL4	HGNC	ENSG00000102271	tier1	-	-	53	0	0.00	8	20	71.43
KLHL4	0	genome.wustl.edu	37	X	86919925	86919925	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	86919925	86919925	A	C	SNP	KLHL4	ENST00000373114	human	ensembl	74_37	+1	known	missense	c.2087	p.E696A	1.000	pfam_Kelch_1,pfam_Kelch_2,smart_Kelch_1	pfam_Kelch_1,pfam_BACK,pfam_BTB_POZ,pfam_Kelch_2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL4	HGNC	ENSG00000102271	tier1	-	-	45	0	0.00	2	23	92.00
KRCC1	0	genome.wustl.edu	37	2	88327832	88327832	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	88327832	88327832	C	T	SNP	KRCC1	ENST00000347055	human	ensembl	74_37	-1	known	missense	c.251	p.R84Q	0.000	NULL	NULL	-	no_errors	KRCC1	HGNC	ENSG00000172086	tier1	-	-	109	0	0.00	43	25	36.76
LAMA1	0	genome.wustl.edu	37	18	7034564	7034564	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	7034564	7034564	A	G	SNP	LAMA1	ENST00000389658	human	ensembl	74_37	-1	known	silent	c.1965	p.D655	0.991	pfam_Laminin_B_type_IV,smart_Laminin_B_subgr,pfscan_Laminin_B_type_IV	pfam_Laminin_G,pfam_EGF_laminin,pfam_Laminin_B_type_IV,pfam_Laminin_N,pfam_Laminin_I,pfam_Laminin_II,superfamily_ConA-like_lec_gl_sf,superfamily_Galactose-bd-like,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,smart_Laminin_G,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_G,pfscan_Laminin_N	-	no_errors	LAMA1	HGNC	ENSG00000101680	tier1	-	-	148	0	0.00	15	51	77.27
LEKR1	0	genome.wustl.edu	37	3	156763476	156763476	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	156763476	156763476	T	G	SNP	LEKR1	ENST00000356539	human	ensembl	74_37	+1	known	silent	c.2016	p.S672	0.954	NULL	superfamily_Ribosomal_L29	-	no_errors	LEKR1	HGNC	ENSG00000197980	tier1	-	-	122	0	0.00	35	37	51.39
LOC101927079	0	genome.wustl.edu	37	15	22332405	22332405	+	RNA	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	22332405	22332405	G	A	SNP	LOC101927079	ENST00000558896	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.170	-	-	-	no_errors	RP11-69H14.6	Clone_based_vega_gene	ENSG00000259176	tier1	-	-	218	0	0.00	107	27	20.15
LOC101927267	0	genome.wustl.edu	37	12	49690876	49690876	+	RNA	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	49690876	49690876	G	A	SNP	LOC101927267	ENST00000553259	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-161H23.9	Clone_based_vega_gene	ENSG00000258334	tier1	-	-	127	0	0.00	11	43	79.63
LOC101929232	0	genome.wustl.edu	37	15	29060599	29060599	+	RNA	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	29060599	29060599	A	C	SNP	LOC101929232	ENST00000563202	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.995	-	-	-	no_errors	RP11-578F21.12	Clone_based_vega_gene	ENSG00000261377	tier1	-	-	134	0	0.00	85	31	26.72
LRFN5	0	genome.wustl.edu	37	14	42356534	42356534	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	42356534	42356534	A	C	SNP	LRFN5	ENST00000298119	human	ensembl	74_37	+1	known	missense	c.706	p.S236R	1.000	NULL	pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	LRFN5	HGNC	ENSG00000165379	tier1	-	-	209	0	0.00	84	55	39.57
LRP1B	0	genome.wustl.edu	37	2	141298623	141298623	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	141298623	141298623	A	G	SNP	LRP1B	ENST00000389484	human	ensembl	74_37	-1	known	silent	c.7432	p.L2478	1.000	smart_EG-like_dom	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EG-like_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1B	HGNC	ENSG00000168702	tier1	-	-	123	0	0.00	42	36	46.15
LRRC18	0	genome.wustl.edu	37	10	50121999	50121999	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	50121999	50121999	A	C	SNP	LRRC18	ENST00000374160	human	ensembl	74_37	-1	known	missense	c.202	p.S68A	0.000	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC18	HGNC	ENSG00000165383	tier1	-	-	118	0	0.00	37	31	44.93
LRRC4C	0	genome.wustl.edu	37	11	40136013	40136013	+	Silent	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	40136013	40136013	T	A	SNP	LRRC4C	ENST00000527150	human	ensembl	74_37	-1	known	silent	c.1830	p.T610	1.000	NULL	pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	LRRC4C	HGNC	ENSG00000148948	tier1	-	-	166	0	0.00	43	37	46.25
MAGEB1	0	genome.wustl.edu	37	X	30269103	30269103	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	30269103	30269103	T	G	SNP	MAGEB1	ENST00000378981	human	ensembl	74_37	+1	known	missense	c.493	p.L165V	0.000	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE	-	no_errors	MAGEB1	HGNC	ENSG00000214107	tier1	-	-	27	0	0.00	2	17	89.47
MAGEB2	0	genome.wustl.edu	37	X	30237207	30237207	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	30237207	30237207	A	C	SNP	MAGEB2	ENST00000378988	human	ensembl	74_37	+1	known	missense	c.510	p.K170N	0.011	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE	-	no_errors	MAGEB2	HGNC	ENSG00000099399	tier1	-	-	38	0	0.00	3	21	87.50
MAGEB3	0	genome.wustl.edu	37	X	30254478	30254478	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	30254478	30254478	A	G	SNP	MAGEB3	ENST00000361644	human	ensembl	74_37	+1	known	missense	c.437	p.K146R	0.000	pfam_MAGE,pfscan_MAGE	pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE	-	no_errors	MAGEB3	HGNC	ENSG00000198798	tier1	-	-	75	0	0.00	8	43	84.31
MAP1B	0	genome.wustl.edu	37	5	71495359	71495359	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	71495359	71495359	C	T	SNP	MAP1B	ENST00000296755	human	ensembl	74_37	+1	known	silent	c.6177	p.Y2059	0.806	NULL	pfam_MAP1B_neuraxin	-	no_errors	MAP1B	HGNC	ENSG00000131711	tier1	-	-	143	0	0.00	39	10	20.41
MBP	0	genome.wustl.edu	37	18	74700336	74700336	+	Missense_Mutation	SNP	G	G	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	74700336	74700336	G	C	SNP	MBP	ENST00000397869	human	ensembl	74_37	-1	novel	missense	c.466	p.R156G	0.000	pfam_Myelin_BP	pfam_Myelin_BP,prints_Myelin_BP	-	no_errors	MBP	HGNC	ENSG00000197971	tier1	-	-	28	0	0.00	4	7	63.64
MED8	0	genome.wustl.edu	37	1	43852281	43852281	+	Frame_Shift_Del	DEL	C	C	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	43852281	43852281	C	-	DEL	MED8	ENST00000290663	human	ensembl	74_37	-1	known	frame_shift_del	c.472	p.E158fs	1.000	pfam_Mediatior_Med8_fun/met	pfam_Mediatior_Med8_fun/met	-	no_errors	MED8	HGNC	ENSG00000159479	tier1			29	0	0.00	9	2	18.18
MTHFD1	0	genome.wustl.edu	37	14	64894060	64894060	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	64894060	64894060	C	T	SNP	MTHFD1	ENST00000216605	human	ensembl	74_37	+1	known	missense	c.1133	p.T378I	1.000	pfam_Formate_THF_ligase,superfamily_P-loop_NTPase	pfam_Formate_THF_ligase,pfam_THF_DH/CycHdrlase_NAD-bd_dom,pfam_THF_DH/CycHdrlase_cat_dom,superfamily_P-loop_NTPase,prints_THF_DH/CycHdrlase	-	no_errors	MTHFD1	HGNC	ENSG00000100714	tier1	-	-	94	0	0.00	27	19	41.30
MTMR4	0	genome.wustl.edu	37	17	56573630	56573630	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	56573630	56573630	T	C	SNP	MTMR4	ENST00000323456	human	ensembl	74_37	-1	known	missense	c.1873	p.T625A	1.000	NULL	pfam_Myotubularin-like_Pase_dom,pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pfscan_Znf_FYVE-rel,pfscan_Tyr/Dual-sp_Pase	-	no_errors	MTMR4	HGNC	ENSG00000108389	tier1	-	-	69	0	0.00	40	26	39.39
MUC5B	0	genome.wustl.edu	37	11	1262688	1262688	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	1262688	1262688	C	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.4587	p.D1529	0.646	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	56	0	0.00	16	6	27.27
MUC5B	0	genome.wustl.edu	37	11	1265684	1265684	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	1265684	1265684	T	A	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	missense	c.7583	p.L2528Q	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	88	0	0.00	20	19	48.72
MYCN	0	genome.wustl.edu	37	2	16082272	16082272	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	16082272	16082272	A	-	DEL	MYCN	ENST00000281043	human	ensembl	74_37	+1	known	frame_shift_del	c.86	p.Y29fs	1.000	pfam_Tscrpt_reg_Myc_N	pfam_Tscrpt_reg_Myc_N,pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom,prints_Tscrpt_reg_Myc	-	no_errors	MYCN	HGNC	ENSG00000134323	tier1			63	0	0.00	15	2	11.76
MYCT1	0	genome.wustl.edu	37	6	153019200	153019200	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	153019200	153019200	A	C	SNP	MYCT1	ENST00000367245	human	ensembl	74_37	+1	known	missense	c.163	p.S55R	0.998	NULL	NULL	-	no_errors	MYCT1	HGNC	ENSG00000120279	tier1	-	-	134	0	0.00	58	30	34.09
MYO3A	0	genome.wustl.edu	37	10	26462802	26462802	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	26462802	26462802	A	C	SNP	MYO3A	ENST00000265944	human	ensembl	74_37	+1	known	missense	c.3609	p.E1203D	0.001	superfamily_P-loop_NTPase	pfam_Myosin_head_motor_dom,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,pfscan_Prot_kinase_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO3A	HGNC	ENSG00000095777	tier1	-	-	104	0	0.00	50	19	27.54
NALCN	0	genome.wustl.edu	37	13	101833582	101833582	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	101833582	101833582	A	C	SNP	NALCN	ENST00000376196	human	ensembl	74_37	-1	known	missense	c.1871	p.L624R	0.000	NULL	pfam_Ion_trans_dom	-	no_errors	NALCN	HGNC	ENSG00000102452	tier1	-	-	113	0	0.00	39	22	36.07
NDST4	0	genome.wustl.edu	37	4	115856423	115856423	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	115856423	115856423	G	T	SNP	NDST4	ENST00000264363	human	ensembl	74_37	-1	known	missense	c.1475	p.P492H	1.000	pfam_Heparan_SO4_deacetylase	pfam_Heparan_SO4_deacetylase,pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	NDST4	HGNC	ENSG00000138653	tier1	-	-	96	0	0.00	49	28	36.36
NF2	0	genome.wustl.edu	37	22	30067882	30067882	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	22	30067882	30067882	T	G	SNP	NF2	ENST00000338641	human	ensembl	74_37	+1	known	missense	c.1067	p.L356W	1.000	pirsf_ERM,pfam_ERM_C_dom,prints_Tropomyosin	pirsf_ERM,pfam_ERM_C_dom,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,superfamily_Moesin_tail,smart_Band_41_domain,pfscan_FERM_domain,prints_Ez/rad/moesin_like,prints_Band_41_fam,prints_Tropomyosin	-	no_errors	NF2	HGNC	ENSG00000186575	tier1	-	-	89	0	0.00	5	23	82.14
NLGN4X	0	genome.wustl.edu	37	X	6069222	6069222	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	6069222	6069222	A	G	SNP	NLGN4X	ENST00000381093	human	ensembl	74_37	-1	known	missense	c.286	p.S96P	0.996	pfam_CarbesteraseB	pfam_CarbesteraseB,pfam_AB_hydrolase_3,prints_Neuroligin	-	no_errors	NLGN4X	HGNC	ENSG00000146938	tier1	-	-	97	0	0.00	6	41	87.23
NOD2	0	genome.wustl.edu	37	16	50733399	50733399	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	50733399	50733399	G	A	SNP	NOD2	ENST00000300589	human	ensembl	74_37	+1	known	missense	c.74	p.G25D	0.992	NULL	pfam_CARD,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_CARD	-	no_errors	NOD2	HGNC	ENSG00000167207	tier1	-	-	252	0	0.00	73	46	38.66
NPY1R	0	genome.wustl.edu	37	4	164246855	164246855	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	164246855	164246855	T	G	SNP	NPY1R	ENST00000296533	human	ensembl	74_37	-1	known	missense	c.755	p.K252T	0.998	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_NPY1_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_Glucose_rcpt_Git3_N,pfscan_GPCR_Rhodpsn_7TM,prints_NPY1_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	NPY1R	HGNC	ENSG00000164128	tier1	-	-	116	0	0.00	42	29	40.85
NR3C1	0	genome.wustl.edu	37	5	142779275	142779275	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	142779275	142779275	G	A	SNP	NR3C1	ENST00000231509	human	ensembl	74_37	-1	known	missense	c.1130	p.S377F	1.000	pfam_Glcrtcd_rcpt	pfam_Glcrtcd_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Glcrtcd_rcpt,prints_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt	-	no_errors	NR3C1	HGNC	ENSG00000113580	tier1	-	-	171	0	0.00	85	5	5.56
NRK	0	genome.wustl.edu	37	X	105168815	105168815	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	105168815	105168815	A	C	SNP	NRK	ENST00000428173	human	ensembl	74_37	+1	known	missense	c.3107	p.E1036A	0.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Citron,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Citron,pfscan_Prot_kinase_dom	-	no_errors	NRK	HGNC	ENSG00000123572	tier1	-	-	21	0	0.00	2	17	89.47
NUMB	0	genome.wustl.edu	37	14	73746075	73746075	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	73746075	73746075	G	T	SNP	NUMB	ENST00000355058	human	ensembl	74_37	-1	known	missense	c.1154	p.A385E	1.000	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMB	HGNC	ENSG00000133961	tier1	-	-	91	0	0.00	26	24	48.00
NXF2B	0	genome.wustl.edu	37	X	101623723	101623723	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	101623723	101623723	T	G	SNP	NXF2B	ENST00000372749	human	ensembl	74_37	-1	known	missense	c.639	p.Q213H	0.119	NULL	pfam_Tap_RNA-bd,pfam_TAP_C_dom,pfam_NTF2,superfamily_UBA-like,smart_TAP_C_dom,pfscan_Nuclear_transport_factor_2_euk	-	no_errors	NXF2B	HGNC	ENSG00000185945	tier1	-	-	153	0	0.00	56	19	25.33
NXPE1	0	genome.wustl.edu	37	11	114393749	114393749	+	Silent	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	114393749	114393749	A	C	SNP	NXPE1	ENST00000424269	human	ensembl	74_37	-1	known	silent	c.960	p.T320	0.018	NULL	pfam_NXPH/NXPE,superfamily_Ig_E-set	-	no_errors	NXPE1	HGNC	ENSG00000095110	tier1	-	-	99	0	0.00	42	17	28.81
OGDHL	0	genome.wustl.edu	37	10	50960708	50960708	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	50960708	50960708	A	C	SNP	OGDHL	ENST00000374103	human	ensembl	74_37	-1	known	missense	c.454	p.L152V	0.998	pirsf_2oxoglutarate_DH_E1,tigrfam_2oxoglutarate_DH_E1	pfam_DH_E1,pfam_Transketolase-like_Pyr-bd,smart_Transketolase-like_Pyr-bd,pirsf_2oxoglutarate_DH_E1,tigrfam_2oxoglutarate_DH_E1	-	no_errors	OGDHL	HGNC	ENSG00000197444	tier1	-	-	73	0	0.00	21	24	53.33
OLFML2B	0	genome.wustl.edu	37	1	161968002	161968002	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	161968002	161968002	C	T	SNP	OLFML2B	ENST00000294794	human	ensembl	74_37	-1	known	missense	c.1087	p.D363N	0.000	NULL	pfam_Olfac-like,superfamily_NA-bd_OB-fold,smart_Olfac-like,pfscan_Olfac-like	-	no_errors	OLFML2B	HGNC	ENSG00000162745	tier1	-	-	194	0	0.00	55	49	47.12
OPRK1	0	genome.wustl.edu	37	8	54147657	54147657	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	54147657	54147657	T	G	SNP	OPRK1	ENST00000265572	human	ensembl	74_37	-1	known	missense	c.272	p.K91T	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,prints_Opioid_rcpt,prints_NPY_rcpt,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfam_7TM_GPCR_serpentine_rcpt_Srx,prints_Kappa_opi_rcpt,prints_GPCR_Rhodpsn,prints_Opioid_rcpt,prints_Neuropept_B/W_rcpt,prints_Somatstn_rcpt,prints_NPY_rcpt,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	OPRK1	HGNC	ENSG00000082556	tier1	-	-	112	0	0.00	53	26	32.91
OR10J3	0	genome.wustl.edu	37	1	159284282	159284282	+	Silent	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	159284282	159284282	A	C	SNP	OR10J3	ENST00000332217	human	ensembl	74_37	-1	known	silent	c.168	p.L56	0.858	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10J3	HGNC	ENSG00000196266	tier1	-	-	164	0	0.00	59	59	50.00
OR14C36	0	genome.wustl.edu	37	1	248512182	248512182	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	248512182	248512182	A	C	SNP	OR14C36	ENST00000317861	human	ensembl	74_37	+1	known	missense	c.106	p.T36P	0.008	pfam_7TM_GPCR_olfarory/Srsx,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR14C36	HGNC	ENSG00000177174	tier1	-	-	171	0	0.00	68	29	29.90
OR2L3	0	genome.wustl.edu	37	1	248224688	248224688	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	248224688	248224688	A	C	SNP	OR2L3	ENST00000359959	human	ensembl	74_37	+1	known	missense	c.705	p.K235N	0.891	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2L3	HGNC	ENSG00000198128	tier1	-	-	204	0	0.00	82	41	33.33
OR2T10	0	genome.wustl.edu	37	1	248756506	248756506	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	248756506	248756506	A	G	SNP	OR2T10	ENST00000330500	human	ensembl	74_37	-1	known	silent	c.564	p.S188	0.995	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2T10	HGNC	ENSG00000184022	tier1	-	-	110	0	0.00	41	30	42.25
OR2T4	0	genome.wustl.edu	37	1	248525579	248525579	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	248525579	248525579	T	G	SNP	OR2T4	ENST00000366475	human	ensembl	74_37	+1	known	missense	c.697	p.L233V	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2T4	HGNC	ENSG00000196944	tier1	-	-	205	0	0.00	81	42	34.15
OR3A1	0	genome.wustl.edu	37	17	3195398	3195398	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	3195398	3195398	A	C	SNP	OR3A1	ENST00000323404	human	ensembl	74_37	-1	known	missense	c.479	p.L160R	0.004	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR3A1	HGNC	ENSG00000180090	tier1	-	-	169	0	0.00	18	34	65.38
OR4K2	0	genome.wustl.edu	37	14	20345002	20345002	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	20345002	20345002	T	C	SNP	OR4K2	ENST00000298642	human	ensembl	74_37	+1	known	silent	c.576	p.T192	0.986	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4K2	HGNC	ENSG00000165762	tier1	-	-	750	0	0.00	390	89	18.58
OR4N2	0	genome.wustl.edu	37	14	20296136	20296136	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	20296136	20296136	T	G	SNP	OR4N2	ENST00000315947	human	ensembl	74_37	+1	known	missense	c.529	p.F177V	0.997	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4N2	HGNC	ENSG00000176294	tier1	-	-	398	0	0.00	215	49	18.56
OR4N2	0	genome.wustl.edu	37	14	20296349	20296349	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	20296349	20296349	T	G	SNP	OR4N2	ENST00000315947	human	ensembl	74_37	+1	known	missense	c.742	p.F248V	0.667	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4N2	HGNC	ENSG00000176294	tier1	-	-	341	0	0.00	176	50	21.93
OR4P4	0	genome.wustl.edu	37	11	55405969	55405969	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	55405969	55405969	T	A	SNP	OR4P4	ENST00000314612	human	ensembl	74_37	+1	known	missense	c.136	p.S46T	0.626	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4P4	HGNC	ENSG00000181927	tier1	-	-	155	0	0.00	64	34	34.69
OR51A7	0	genome.wustl.edu	37	11	4929411	4929411	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	4929411	4929411	T	G	SNP	OR51A7	ENST00000359350	human	ensembl	74_37	+1	known	missense	c.812	p.V271G	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	OR51A7	HGNC	ENSG00000176895	tier1	-	-	207	0	0.00	68	50	42.37
OR51M1	0	genome.wustl.edu	37	11	5410825	5410825	+	Missense_Mutation	SNP	G	G	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	5410825	5410825	G	C	SNP	OR51M1	ENST00000328611	human	ensembl	74_37	+1	known	missense	c.197	p.R66P	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR51M1	HGNC	ENSG00000184698	tier1	-	-	129	0	0.00	28	45	60.81
OR51S1	0	genome.wustl.edu	37	11	4870378	4870378	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	4870378	4870378	A	C	SNP	OR51S1	ENST00000322101	human	ensembl	74_37	-1	known	missense	c.61	p.L21V	0.171	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR51S1	HGNC	ENSG00000176922	tier1	-	-	128	0	0.00	32	28	46.67
OR52J3	0	genome.wustl.edu	37	11	5068434	5068434	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	5068434	5068434	T	G	SNP	OR52J3	ENST00000380370	human	ensembl	74_37	+1	known	missense	c.679	p.F227V	0.168	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR52J3	HGNC	ENSG00000205495	tier1	-	-	195	0	0.00	45	44	49.44
OR56A3	0	genome.wustl.edu	37	11	5969504	5969504	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	5969504	5969504	T	G	SNP	OR56A3	ENST00000329564	human	ensembl	74_37	+1	known	missense	c.928	p.L310V	0.004	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR56A3	HGNC	ENSG00000184478	tier1	-	-	94	0	0.00	43	14	24.56
OR5D13	0	genome.wustl.edu	37	11	55541046	55541046	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	55541046	55541046	T	G	SNP	OR5D13	ENST00000361760	human	ensembl	74_37	+1	known	missense	c.133	p.L45V	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5D13	HGNC	ENSG00000198877	tier1	-	-	192	0	0.00	59	41	41.00
OR6N2	0	genome.wustl.edu	37	1	158747082	158747082	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	158747082	158747082	A	G	SNP	OR6N2	ENST00000339258	human	ensembl	74_37	-1	known	missense	c.344	p.L115P	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6N2	HGNC	ENSG00000188340	tier1	-	-	106	0	0.00	64	28	30.43
ORC2	0	genome.wustl.edu	37	2	201796105	201796105	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	201796105	201796105	G	A	SNP	ORC2	ENST00000234296	human	ensembl	74_37	-1	known	nonsense	c.874	p.Q292*	0.999	pfam_ORC2	pfam_ORC2	-	no_errors	ORC2	HGNC	ENSG00000115942	tier1	-	-	120	0	0.00	39	18	31.58
PAG1	0	genome.wustl.edu	37	8	81905433	81905433	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	81905433	81905433	G	A	SNP	PAG1	ENST00000220597	human	ensembl	74_37	-1	known	silent	c.30	p.S10	0.000	NULL	NULL	-	no_errors	PAG1	HGNC	ENSG00000076641	tier1	-	-	48	0	0.00	22	12	35.29
PAPD5	0	genome.wustl.edu	37	16	50257227	50257227	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	50257227	50257227	A	G	SNP	PAPD5	ENST00000436909	human	ensembl	74_37	+1	known	missense	c.1265	p.D422G	1.000	pfam_PAP_assoc	pfam_PAP_assoc,pfam_Nucleotidyltransferase	-	no_errors	PAPD5	HGNC	ENSG00000121274	tier1	-	-	51	0	0.00	22	5	18.52
PAPPA	0	genome.wustl.edu	37	9	118950133	118950133	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	118950133	118950133	C	T	SNP	PAPPA	ENST00000328252	human	ensembl	74_37	+1	known	silent	c.1116	p.R372	0.657	NULL	pfam_Sushi_SCR_CCP,pfam_Notch_dom,pfam_Peptidase_M43,superfamily_ConA-like_lec_gl_sf,superfamily_Sushi_SCR_CCP,superfamily_Fibronectin_type3,superfamily_Notch_dom,smart_LamG-like,smart_Notch_dom,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP,tigrfam_Myxo_disulph_rpt	-	no_errors	PAPPA	HGNC	ENSG00000182752	tier1	rs201148082	-	45	0	0.00	16	9	36.00
PARD3B	0	genome.wustl.edu	37	2	206166297	206166297	+	Silent	SNP	C	C	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	206166297	206166297	C	G	SNP	PARD3B	ENST00000406610	human	ensembl	74_37	+1	known	silent	c.2502	p.V834	0.617	NULL	pfam_DUF3534,pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	PARD3B	HGNC	ENSG00000116117	tier1	-	-	76	0	0.00	6	21	77.78
PARVG	0	genome.wustl.edu	37	22	44581750	44581750	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	22	44581750	44581750	A	-	DEL	PARVG	ENST00000415224	human	ensembl	74_37	+1	known	frame_shift_del	c.142	p.K48fs	0.952	pfam_CH-domain,superfamily_CH-domain,pfscan_CH-domain	pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	PARVG	HGNC	ENSG00000138964	tier1			40	0	0.00	7	2	22.22
PCDH20	0	genome.wustl.edu	37	13	61986022	61986022	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	61986022	61986022	T	C	SNP	PCDH20	ENST00000409186	human	ensembl	74_37	-1	known	missense	c.2210	p.D737G	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH20	HGNC	ENSG00000197991	tier1	-	-	160	0	0.00	68	44	39.29
PCDHA9	0	genome.wustl.edu	37	5	140228896	140228896	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	140228896	140228896	C	T	SNP	PCDHA9	ENST00000532602	human	ensembl	74_37	+1	known	silent	c.816	p.G272	0.003	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA9	HGNC	ENSG00000204961	tier1	-	-	20	0	0.00	6	3	33.33
PCDHB7	0	genome.wustl.edu	37	5	140553262	140553262	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	140553262	140553262	T	C	SNP	PCDHB7	ENST00000231137	human	ensembl	74_37	+1	known	silent	c.846	p.S282	0.011	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHB7	HGNC	ENSG00000113212	tier1	-	-	136	0	0.00	41	28	40.58
PDHA2	0	genome.wustl.edu	37	4	96761606	96761606	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	96761606	96761606	T	G	SNP	PDHA2	ENST00000295266	human	ensembl	74_37	+1	known	missense	c.305	p.L102R	0.043	pfam_DH_E1,tigrfam_Pyrv_DH_E1_asu_subgrp-y	pfam_DH_E1,tigrfam_Pyrv_DH_E1_asu_subgrp-y	-	no_errors	PDHA2	HGNC	ENSG00000163114	tier1	-	-	209	0	0.00	55	70	55.56
PDIA5	0	genome.wustl.edu	37	3	122843139	122843139	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	122843139	122843139	A	C	SNP	PDIA5	ENST00000316218	human	ensembl	74_37	+1	known	missense	c.722	p.Q241P	1.000	pfam_Thioredoxin_domain,superfamily_Thioredoxin-like_fold	pfam_Thioredoxin_domain,pfam_AhpC/TSA,superfamily_Thioredoxin-like_fold,prints_Thioredoxin	-	no_errors	PDIA5	HGNC	ENSG00000065485	tier1	-	-	239	0	0.00	42	56	57.14
PDZRN3	0	genome.wustl.edu	37	3	73440209	73440209	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	73440209	73440209	C	T	SNP	PDZRN3	ENST00000263666	human	ensembl	74_37	-1	known	missense	c.1313	p.R438Q	1.000	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	pfam_PDZ,pfam_Znf_C3HC4_RING-type,superfamily_PDZ,superfamily_TRAF-like,smart_Znf_RING,smart_PDZ,pfscan_PDZ,pfscan_Znf_RING,pfscan_Znf_TRAF	-	no_errors	PDZRN3	HGNC	ENSG00000121440	tier1	-	-	332	0	0.00	28	91	75.83
PDZRN3	0	genome.wustl.edu	37	3	73440210	73440210	+	Silent	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	73440210	73440210	G	T	SNP	PDZRN3	ENST00000263666	human	ensembl	74_37	-1	known	silent	c.1312	p.R438	1.000	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	pfam_PDZ,pfam_Znf_C3HC4_RING-type,superfamily_PDZ,superfamily_TRAF-like,smart_Znf_RING,smart_PDZ,pfscan_PDZ,pfscan_Znf_RING,pfscan_Znf_TRAF	-	no_errors	PDZRN3	HGNC	ENSG00000121440	tier1	-	-	333	0	0.00	29	92	76.03
PEG3	0	genome.wustl.edu	37	19	57325616	57325616	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	57325616	57325616	T	G	SNP	PEG3	ENST00000326441	human	ensembl	74_37	-1	known	missense	c.4194	p.E1398D	0.010	NULL	pfam_Znf_C2H2,pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	PEG3	HGNC	ENSG00000198300	tier1	-	-	105	0	0.00	40	30	42.86
PGBD2	0	genome.wustl.edu	37	1	249211740	249211740	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	249211740	249211740	G	A	SNP	PGBD2	ENST00000329291	human	ensembl	74_37	+1	known	silent	c.957	p.K319	0.028	NULL	NULL	-	no_errors	PGBD2	HGNC	ENSG00000185220	tier1	rs150759335	-	196	0	0.00	68	63	48.09
PHF2	0	genome.wustl.edu	37	9	96408055	96408055	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	96408055	96408055	C	T	SNP	PHF2	ENST00000359246	human	ensembl	74_37	+1	known	silent	c.444	p.D148	0.514	NULL	pfam_JmjC_dom,pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_JmjC_dom,pfscan_JmjC_dom,pfscan_Znf_PHD-finger	-	no_errors	PHF2	HGNC	ENSG00000197724	tier1	-	-	69	0	0.00	28	10	26.32
PKHD1	0	genome.wustl.edu	37	6	51512849	51512849	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	51512849	51512849	G	T	SNP	PKHD1	ENST00000371117	human	ensembl	74_37	-1	known	missense	c.11378	p.A3793E	0.003	NULL	pfam_IPT,pfam_G8_domain,superfamily_Ig_E-set,superfamily_Pectin_lyase_fold/virulence,smart_IPT,smart_PbH1	-	no_errors	PKHD1	HGNC	ENSG00000170927	tier1	-	-	98	0	0.00	37	29	43.94
POSTN	0	genome.wustl.edu	37	13	38153490	38153490	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	38153490	38153490	T	A	SNP	POSTN	ENST00000379747	human	ensembl	74_37	-1	known	missense	c.1667	p.K556I	1.000	pfam_FAS1_domain,superfamily_FAS1_domain,smart_FAS1_domain,pirsf_TGFb-ind_bIGH3/osteoblast_fac2,pfscan_FAS1_domain	pfam_FAS1_domain,superfamily_FAS1_domain,smart_FAS1_domain,pirsf_TGFb-ind_bIGH3/osteoblast_fac2,pfscan_EMI_domain,pfscan_FAS1_domain	-	no_errors	POSTN	HGNC	ENSG00000133110	tier1	-	-	153	0	0.00	43	37	45.68
POSTN	0	genome.wustl.edu	37	13	38154749	38154749	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	38154749	38154749	T	C	SNP	POSTN	ENST00000379747	human	ensembl	74_37	-1	known	missense	c.1478	p.K493R	0.990	pfam_FAS1_domain,superfamily_FAS1_domain,smart_FAS1_domain,pirsf_TGFb-ind_bIGH3/osteoblast_fac2	pfam_FAS1_domain,superfamily_FAS1_domain,smart_FAS1_domain,pirsf_TGFb-ind_bIGH3/osteoblast_fac2,pfscan_EMI_domain,pfscan_FAS1_domain	-	no_errors	POSTN	HGNC	ENSG00000133110	tier1	-	-	214	0	0.00	94	60	38.96
POTEM	0	genome.wustl.edu	37	14	19990584	19990584	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	19990584	19990584	T	C	SNP	POTEM	ENST00000551509	human	ensembl	74_37	-1	novel	silent	c.1491	p.E497	0.008	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	POTEM	HGNC	ENSG00000187537	tier1	-	-	38	0	0.00	20	3	13.04
PPP1R3A	0	genome.wustl.edu	37	7	113518542	113518542	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	113518542	113518542	A	C	SNP	PPP1R3A	ENST00000284601	human	ensembl	74_37	-1	known	missense	c.2605	p.L869V	0.003	NULL	pfam_CBM_21,pfscan_CBM_21	-	no_errors	PPP1R3A	HGNC	ENSG00000154415	tier1	-	-	145	0	0.00	42	50	54.35
PPP1R3A	0	genome.wustl.edu	37	7	113558642	113558642	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	113558642	113558642	A	G	SNP	PPP1R3A	ENST00000284601	human	ensembl	74_37	-1	known	missense	c.410	p.L137P	1.000	pfam_CBM_21,pfscan_CBM_21	pfam_CBM_21,pfscan_CBM_21	-	no_errors	PPP1R3A	HGNC	ENSG00000154415	tier1	-	-	134	0	0.00	61	55	47.41
PRAMEF2	0	genome.wustl.edu	37	1	12921521	12921521	+	Missense_Mutation	SNP	A	A	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	12921521	12921521	A	T	SNP	PRAMEF2	ENST00000240189	human	ensembl	74_37	+1	known	missense	c.1312	p.M438L	0.011	NULL	NULL	-	no_errors	PRAMEF2	HGNC	ENSG00000120952	tier1	-	-	237	0	0.00	70	56	44.09
PRAMEF4	0	genome.wustl.edu	37	1	12939842	12939842	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	12939842	12939842	C	T	SNP	PRAMEF4	ENST00000235349	human	ensembl	74_37	-1	known	silent	c.960	p.P320	0.000	NULL	NULL	-	no_errors	PRAMEF4	HGNC	ENSG00000243073	tier1	-	-	432	0	0.00	139	104	42.80
PRAMEF7	0	genome.wustl.edu	37	1	12979843	12979843	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	12979843	12979843	A	C	SNP	PRAMEF7	ENST00000330881	human	ensembl	74_37	+1	known	missense	c.1035	p.Q345H	0.000	NULL	NULL	-	no_errors	PRAMEF7	HGNC	ENSG00000204510	tier1	-	-	170	0	0.00	61	27	30.68
PREX2	0	genome.wustl.edu	37	8	69031715	69031715	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	69031715	69031715	A	C	SNP	PREX2	ENST00000288368	human	ensembl	74_37	+1	known	missense	c.3470	p.K1157T	1.000	NULL	pfam_DH-domain,pfam_DEP_dom,pfam_PDZ,superfamily_DH-domain,superfamily_PDZ,smart_DH-domain,smart_Pleckstrin_homology,smart_DEP_dom,smart_PDZ,pfscan_DEP_dom,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PREX2	HGNC	ENSG00000046889	tier1	-	-	216	0	0.00	118	59	33.33
PREX2	0	genome.wustl.edu	37	8	69046509	69046509	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	69046509	69046509	T	G	SNP	PREX2	ENST00000288368	human	ensembl	74_37	+1	known	missense	c.3982	p.L1328V	1.000	NULL	pfam_DH-domain,pfam_DEP_dom,pfam_PDZ,superfamily_DH-domain,superfamily_PDZ,smart_DH-domain,smart_Pleckstrin_homology,smart_DEP_dom,smart_PDZ,pfscan_DEP_dom,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PREX2	HGNC	ENSG00000046889	tier1	-	-	40	0	0.00	28	16	36.36
PRUNE2	0	genome.wustl.edu	37	9	79325757	79325757	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	79325757	79325757	G	A	SNP	PRUNE2	ENST00000428286	human	ensembl	74_37	-1	known	missense	c.356	p.A119V	0.144	NULL	pfam_Bcl2-/adenovirus-E1B,pfam_CRAL-TRIO_dom,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom	-	no_errors	PRUNE2	HGNC	ENSG00000106772	tier1	-	-	52	0	0.00	20	16	44.44
PTGER3	0	genome.wustl.edu	37	1	71418602	71418602	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	71418602	71418602	T	C	SNP	PTGER3	ENST00000356595	human	ensembl	74_37	-1	known	silent	c.1245	p.V415	0.000	NULL	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_serpentine_rcpt_Srbc,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_Prostglndn_EP3_rcpt,prints_Prostanoid_rcpt,prints_EP3_rcpt_2,prints_Prostglndn_DP_rcpt,prints_GPCR_Rhodpsn,prints_Thbox_rcpt	-	no_errors	PTGER3	HGNC	ENSG00000050628	tier1	-	-	176	0	0.00	48	46	48.94
PTPN13	0	genome.wustl.edu	37	4	87622674	87622674	+	Missense_Mutation	SNP	G	G	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	87622674	87622674	G	T	SNP	PTPN13	ENST00000436978	human	ensembl	74_37	+1	known	missense	c.915	p.L305F	1.000	pirsf_Tyr_Pase_non-rcpt_typ-13	pirsf_Tyr_Pase_non-rcpt_typ-13,pfam_Tyr_Pase_rcpt/non-rcpt,pfam_PDZ,pfam_FERM_central,pfam_FERM_PH-like_C,pfam_FERM_N,superfamily_FERM_central,superfamily_PDZ,superfamily_PAZ_dom,smart_KIND,smart_Band_41_domain,smart_PDZ,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,prints_Tyr_Pase_rcpt/non-rcpt,prints_Band_41_fam,pfscan_FERM_domain,pfscan_PDZ,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPN13	HGNC	ENSG00000163629	tier1	-	-	78	0	0.00	22	18	45.00
PTPRK	0	genome.wustl.edu	37	6	128505687	128505687	+	Nonsense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	128505687	128505687	C	T	SNP	PTPRK	ENST00000368227	human	ensembl	74_37	-1	known	nonsense	c.1052	p.W351*	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_MAM_dom,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_MAM_dom,smart_Ig_sub,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_MAM_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt,prints_MAM_dom	-	no_errors	PTPRK	HGNC	ENSG00000152894	tier1	-	-	240	0	0.00	90	59	39.60
PTPRS	0	genome.wustl.edu	37	19	5208390	5208390	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	5208390	5208390	G	A	SNP	PTPRS	ENST00000372412	human	ensembl	74_37	-1	known	missense	c.5503	p.R1835W	0.996	pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_rcpt/non-rcpt,pfscan_Tyr_Pase_rcpt/non-rcpt	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,prints_Tyr_Pase_rcpt/non-rcpt,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom	-	no_errors	PTPRS	HGNC	ENSG00000105426	tier1	-	-	79	0	0.00	6	13	68.42
PYHIN1	0	genome.wustl.edu	37	1	158913740	158913740	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	158913740	158913740	T	C	SNP	PYHIN1	ENST00000368140	human	ensembl	74_37	+1	known	missense	c.1163	p.L388P	0.011	pfscan_HIN200/IF120x	pfam_HIN200/IF120x,pfam_DAPIN,superfamily_DEATH-like_dom,pfscan_DAPIN,pfscan_HIN200/IF120x	-	no_errors	PYHIN1	HGNC	ENSG00000163564	tier1	-	-	78	0	0.00	38	27	41.54
QSOX2	0	genome.wustl.edu	37	9	139108532	139108532	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	139108532	139108532	C	T	SNP	QSOX2	ENST00000358701	human	ensembl	74_37	-1	known	missense	c.1123	p.E375K	1.000	NULL	pfam_ERV/ALR_sulphydryl_oxidase,pfam_Thioredoxin_domain,superfamily_ERV/ALR_sulphydryl_oxidase,superfamily_Thioredoxin-like_fold	-	no_errors	QSOX2	HGNC	ENSG00000165661	tier1	-	-	118	0	0.00	32	25	43.86
RANBP17	0	genome.wustl.edu	37	5	170395365	170395365	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	170395365	170395365	T	G	SNP	RANBP17	ENST00000523189	human	ensembl	74_37	+1	known	missense	c.1694	p.L565R	1.000	superfamily_ARM-type_fold	pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N	-	no_errors	RANBP17	HGNC	ENSG00000204764	tier1	-	-	140	0	0.00	41	33	44.59
RFPL4B	0	genome.wustl.edu	37	6	112671050	112671050	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	112671050	112671050	C	T	SNP	RFPL4B	ENST00000441065	human	ensembl	74_37	+1	known	missense	c.140	p.A47V	0.000	smart_Znf_RING,pfscan_Znf_RING	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	RFPL4B	HGNC	ENSG00000251258	tier1	-	-	50	0	0.00	16	7	30.43
RGPD3	0	genome.wustl.edu	37	2	107041249	107041249	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	107041249	107041249	T	G	SNP	RGPD3	ENST00000304514	human	ensembl	74_37	-1	known	missense	c.3174	p.K1058N	1.000	pfam_Ran_bind_dom,smart_Ran_bind_dom,pfscan_Ran_bind_dom	pfam_Ran_bind_dom,pfam_GRIP,pfam_TPR_1,pfam_TPR_2,smart_TPR_repeat,smart_Ran_bind_dom,smart_GRIP,pfscan_GRIP,pfscan_TPR_repeat,pfscan_TPR-contain_dom,pfscan_Ran_bind_dom	-	no_errors	RGPD3	HGNC	ENSG00000153165	tier1	-	-	634	0	0.00	258	167	39.02
RGS7	0	genome.wustl.edu	37	1	241031960	241031960	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	241031960	241031960	T	A	SNP	RGS7	ENST00000407727	human	ensembl	74_37	-1	known	missense	c.536	p.K179M	1.000	NULL	pfam_RGS_dom,pfam_G-protein_gamma-like_dom,pfam_DEP_dom,superfamily_Regulat_G_prot_signal_superfam,superfamily_G-protein_gamma-like_dom,smart_DEP_dom,smart_G-protein_gamma-like_dom,smart_Regulat_G_prot_signal_superfam,pfscan_DEP_dom,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS7	HGNC	ENSG00000182901	tier1	-	-	59	0	0.00	25	21	45.65
RIMS2	0	genome.wustl.edu	37	8	104898091	104898091	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	104898091	104898091	A	C	SNP	RIMS2	ENST00000406091	human	ensembl	74_37	+1	known	missense	c.1264	p.S422R	1.000	NULL	pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_Znf_FYVE_PHD,superfamily_PDZ,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ,pfscan_Znf_FYVE-typ,pfscan_Znf_FYVE-rel	-	no_errors	RIMS2	HGNC	ENSG00000176406	tier1	-	-	57	0	0.00	22	25	53.19
ROR2	0	genome.wustl.edu	37	9	94487215	94487215	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	94487215	94487215	A	C	SNP	ROR2	ENST00000375708	human	ensembl	74_37	-1	known	missense	c.1561	p.F521V	1.000	pirsf_Tyr_kinase_rcpt_ROR,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_rcpt_ROR,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Kringle,pfam_Frizzled_dom,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Kinase-like_dom,superfamily_Kringle-like,superfamily_Frizzled_dom,smart_Ig_sub,smart_Ig_sub2,smart_Kringle,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Frizzled_dom,pfscan_Kringle,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	ROR2	HGNC	ENSG00000169071	tier1	-	-	107	0	0.00	63	33	34.02
RPL6P27	0	genome.wustl.edu	37	18	6462496	6462496	+	RNA	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	18	6462496	6462496	A	C	SNP	RPL6P27	ENST00000583065	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.993	-	-	-	no_errors	RPL6P27	HGNC	ENSG00000235552	tier1	-	-	44	0	0.00	5	14	70.00
RYR3	0	genome.wustl.edu	37	15	34130587	34130587	+	Missense_Mutation	SNP	C	C	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	34130587	34130587	C	G	SNP	RYR3	ENST00000389232	human	ensembl	74_37	+1	known	missense	c.12406	p.L4136V	0.001	superfamily_ARM-type_fold	pfam_Ryanodine_rcpt,pfam_Ca-rel_channel,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_4_helix_cytokine-like_core,superfamily_ARM-type_fold,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR3	HGNC	ENSG00000198838	tier1	-	-	177	0	0.00	75	34	31.19
SACS	0	genome.wustl.edu	37	13	23909805	23909805	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	23909805	23909805	A	C	SNP	SACS	ENST00000382292	human	ensembl	74_37	-1	known	missense	c.8210	p.L2737R	1.000	superfamily_HATPase_ATP-bd	pfam_HEPN,pfam_Ubiquitin_dom,superfamily_HATPase_ATP-bd,superfamily_DnaJ_domain,smart_HEPN,pfscan_HEPN,pfscan_DnaJ_domain,pfscan_Ubiquitin_supergroup	-	no_errors	SACS	HGNC	ENSG00000151835	tier1	-	-	148	0	0.00	54	39	41.94
SACS	0	genome.wustl.edu	37	13	23912736	23912736	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	23912736	23912736	A	C	SNP	SACS	ENST00000382292	human	ensembl	74_37	-1	known	missense	c.5279	p.L1760R	1.000	NULL	pfam_HEPN,pfam_Ubiquitin_dom,superfamily_HATPase_ATP-bd,superfamily_DnaJ_domain,smart_HEPN,pfscan_HEPN,pfscan_DnaJ_domain,pfscan_Ubiquitin_supergroup	-	no_errors	SACS	HGNC	ENSG00000151835	tier1	-	-	218	0	0.00	87	57	39.58
SBF2	0	genome.wustl.edu	37	11	9878255	9878255	+	Missense_Mutation	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	9878255	9878255	C	A	SNP	SBF2	ENST00000256190	human	ensembl	74_37	-1	known	missense	c.2113	p.D705Y	0.995	pfam_SBF2	pfam_SBF2,pfam_DENN_dom,pfam_uDENN_dom,pfam_Myotubularin-like_Pase_dom,pfam_dDENN_dom,pfam_Pleckstrin_homology,pfam_GRAM,smart_uDENN_dom,smart_DENN_dom,smart_dDENN_dom,smart_GRAM,smart_Pleckstrin_homology,pfscan_DENN_dom,pfscan_uDENN_dom,pfscan_dDENN_dom,pfscan_Pleckstrin_homology	-	no_errors	SBF2	HGNC	ENSG00000133812	tier1	-	-	304	0	0.00	117	50	29.94
SCN7A	0	genome.wustl.edu	37	2	167334203	167334203	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	167334203	167334203	A	C	SNP	SCN7A	ENST00000409855	human	ensembl	74_37	-1	known	missense	c.4	p.L2V	0.620	NULL	pfam_Ion_trans_dom,pfam_Na_trans_assoc,prints_Na_channel_asu	-	no_errors	SCN7A	HGNC	ENSG00000136546	tier1	-	-	25	0	0.00	5	7	58.33
SELRC1	0	genome.wustl.edu	37	1	53153823	53153823	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	53153823	53153823	G	A	SNP	SELRC1	ENST00000371538	human	ensembl	74_37	-1	known	silent	c.265	p.L89	1.000	pfam_Sel1-like,smart_Sel1-like	pfam_Sel1-like,smart_Sel1-like	-	no_errors	SELRC1	HGNC	ENSG00000162377	tier1	-	-	32	0	0.00	18	7	28.00
SEMA3D	0	genome.wustl.edu	37	7	84636209	84636209	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	84636209	84636209	A	C	SNP	SEMA3D	ENST00000284136	human	ensembl	74_37	-1	known	missense	c.1817	p.F606C	1.000	smart_Ig_sub	pfam_Semap_dom,pfam_Ig_V-set,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Ig_sub,pfscan_Semap_dom,pfscan_Ig-like_dom	-	no_errors	SEMA3D	HGNC	ENSG00000153993	tier1	-	-	166	0	0.00	63	69	52.27
SEMA5A	0	genome.wustl.edu	37	5	9044617	9044617	+	Silent	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	9044617	9044617	A	C	SNP	SEMA5A	ENST00000382496	human	ensembl	74_37	-1	known	silent	c.2973	p.T991	0.979	NULL	pfam_Semap_dom,pfam_Thrombospondin_1_rpt,superfamily_Semap_dom,superfamily_Thrombospondin_1_rpt,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Thrombospondin_1_rpt,pfscan_Semap_dom,pfscan_Thrombospondin_1_rpt	-	no_errors	SEMA5A	HGNC	ENSG00000112902	tier1	-	-	175	0	0.00	61	39	39.00
SEMA6D	0	genome.wustl.edu	37	15	48063126	48063126	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	48063126	48063126	A	C	SNP	SEMA6D	ENST00000316364	human	ensembl	74_37	+1	known	missense	c.2366	p.K789T	1.000	NULL	pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom	-	no_errors	SEMA6D	HGNC	ENSG00000137872	tier1	-	-	90	0	0.00	30	19	38.00
SFRP1	0	genome.wustl.edu	37	8	41122690	41122690	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	41122690	41122690	T	G	SNP	SFRP1	ENST00000220772	human	ensembl	74_37	-1	known	missense	c.941	p.K314T	1.000	NULL	pfam_Frizzled_dom,pfam_Netrin_module_non-TIMP,superfamily_Frizzled_dom,superfamily_TIMP-like_OB-fold,smart_Frizzled_dom,smart_Netrin_module_non-TIMP,pfscan_Frizzled_dom,pfscan_Netrin_domain	-	no_errors	SFRP1	HGNC	ENSG00000104332	tier1	-	-	16	0	0.00	8	5	38.46
SHCBP1	0	genome.wustl.edu	37	16	46649918	46649918	+	Nonsense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	16	46649918	46649918	C	T	SNP	SHCBP1	ENST00000303383	human	ensembl	74_37	-1	known	nonsense	c.536	p.W179*	1.000	NULL	superfamily_Pectin_lyase_fold/virulence,smart_PbH1	-	no_errors	SHCBP1	HGNC	ENSG00000171241	tier1	-	-	275	0	0.00	153	20	11.49
SLC12A1	0	genome.wustl.edu	37	15	48499982	48499982	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	48499982	48499982	A	C	SNP	SLC12A1	ENST00000380993	human	ensembl	74_37	+1	known	missense	c.66	p.Q22H	1.000	NULL	pfam_AA-permease/SLC12A_dom,pfam_AA_permease_N,prints_Na/K/Cl_cotranspt2,prints_Na/K/Cl_cotranspt,tigrfam_Na/K/Cl_cotransptS	-	no_errors	SLC12A1	HGNC	ENSG00000074803	tier1	-	-	53	0	0.00	17	5	22.73
SLC44A5	0	genome.wustl.edu	37	1	75681467	75681467	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	75681467	75681467	T	G	SNP	SLC44A5	ENST00000370855	human	ensembl	74_37	-1	known	missense	c.1700	p.K567T	1.000	pfam_Choline_transptr-like	pfam_Choline_transptr-like	-	no_errors	SLC44A5	HGNC	ENSG00000137968	tier1	-	-	74	0	0.00	41	14	25.45
SLCO1B1	0	genome.wustl.edu	37	12	21331643	21331643	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	21331643	21331643	T	G	SNP	SLCO1B1	ENST00000256958	human	ensembl	74_37	+1	known	silent	c.615	p.S205	0.942	pfam_OA_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1B1	HGNC	ENSG00000134538	tier1	-	-	138	0	0.00	12	193	94.15
SLITRK3	0	genome.wustl.edu	37	3	164908242	164908242	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	164908242	164908242	A	C	SNP	SLITRK3	ENST00000241274	human	ensembl	74_37	-1	known	missense	c.377	p.I126S	0.993	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C	-	no_errors	SLITRK3	HGNC	ENSG00000121871	tier1	-	-	86	0	0.00	38	11	22.00
SNORA76	0	genome.wustl.edu	37	17	62223681	62223682	+	RNA	DEL	GT	GT	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	GT	GT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	62223681	62223682	GT	-	DEL	SNORA76	ENST00000582965	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	SNORA76	HGNC	ENSG00000266402	tier1			169	0	0.00	53	29	35.37
SORCS1	0	genome.wustl.edu	37	10	108459040	108459040	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	10	108459040	108459040	T	C	SNP	SORCS1	ENST00000344440	human	ensembl	74_37	-1	known	missense	c.1345	p.T449A	1.000	smart_VPS10	pfam_PKD_dom,superfamily_PKD_dom,smart_VPS10,pfscan_PKD_dom	-	no_errors	SORCS1	HGNC	ENSG00000108018	tier1	-	-	126	0	0.00	34	26	43.33
SOX17	0	genome.wustl.edu	37	8	55371645	55371645	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	55371645	55371645	C	T	SNP	SOX17	ENST00000297316	human	ensembl	74_37	+1	known	missense	c.335	p.A112V	0.977	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	pfam_Sox_C_TAD,pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	SOX17	HGNC	ENSG00000164736	tier1	-	-	29	0	0.00	8	6	42.86
SPOCK1	0	genome.wustl.edu	37	5	136324248	136324248	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	5	136324248	136324248	A	C	SNP	SPOCK1	ENST00000282223	human	ensembl	74_37	-1	known	missense	c.791	p.L264R	1.000	pfam_SPARC/Testican_Ca-bd-dom	pfam_SPARC/Testican_Ca-bd-dom,pfam_Thyroglobulin_1,pfam_Kazal_dom,superfamily_Thyroglobulin_1,smart_Kazal_dom,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	-	no_errors	SPOCK1	HGNC	ENSG00000152377	tier1	-	-	100	0	0.00	15	17	53.12
SPRR3	0	genome.wustl.edu	37	1	152975804	152975804	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	152975804	152975804	A	C	SNP	SPRR3	ENST00000295367	human	ensembl	74_37	+1	known	missense	c.308	p.E103A	0.658	pfam_Cornifin	pfam_Cornifin	-	no_errors	SPRR3	HGNC	ENSG00000163209	tier1	-	-	99	0	0.00	56	31	35.63
SRSF6	0	genome.wustl.edu	37	20	42086678	42086678	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	20	42086678	42086678	C	T	SNP	SRSF6	ENST00000244020	human	ensembl	74_37	+1	known	missense	c.5	p.P2L	1.000	pfscan_RRM_dom	pfam_RRM_dom,pfam_RRM_3,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	SRSF6	HGNC	ENSG00000124193	tier1	-	-	43	0	0.00	16	10	38.46
STAG3	0	genome.wustl.edu	37	7	99796147	99796147	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	99796147	99796147	G	A	SNP	STAG3	ENST00000317296	human	ensembl	74_37	+1	known	missense	c.1294	p.V432I	0.519	superfamily_ARM-type_fold	pfam_STAG,superfamily_ARM-type_fold	-	no_errors	STAG3	HGNC	ENSG00000066923	tier1	-	-	130	0	0.00	80	13	13.98
STK11	0	genome.wustl.edu	37	19	1207114	1207116	+	In_Frame_Del	DEL	GAC	GAC	-			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	GAC	GAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	1207114	1207116	GAC	-	DEL	STK11	ENST00000326873	human	ensembl	74_37	+1	known	in_frame_del	c.202_204	p.D68in_frame_del	1.000:1.000:1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	STK11	HGNC	ENSG00000118046	tier1			41	0	0.00	2	3	60.00
STK40	0	genome.wustl.edu	37	1	36823906	36823906	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	36823906	36823906	G	A	SNP	STK40	ENST00000373130	human	ensembl	74_37	-1	known	silent	c.291	p.T97	0.924	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	STK40	HGNC	ENSG00000196182	tier1	-	-	62	0	0.00	10	19	65.52
STL	0	genome.wustl.edu	37	6	125232069	125232069	+	RNA	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	125232069	125232069	T	G	SNP	STL	ENST00000439075	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-510H23.1	Clone_based_vega_gene	ENSG00000236548	tier1	-	-	69	0	0.00	25	21	45.65
STRC	0	genome.wustl.edu	37	15	43900402	43900402	+	Splice_Site	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	15	43900402	43900402	C	T	SNP	STRC	ENST00000450892	human	ensembl	74_37	-1	known	splice_site	c.3558-1	e17-1	1.000	-	-	-	no_errors	STRC	HGNC	ENSG00000242866	tier1	-	-	28	0	0.00	20	9	31.03
STRN3	0	genome.wustl.edu	37	14	31416392	31416392	+	Missense_Mutation	SNP	G	G	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	14	31416392	31416392	G	C	SNP	STRN3	ENST00000357479	human	ensembl	74_37	-1	known	missense	c.620	p.S207C	1.000	NULL	pfam_Striatin_N,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,prints_G-protein_beta_WD-40_rep,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	STRN3	HGNC	ENSG00000196792	tier1	-	-	166	0	0.00	73	51	41.13
TAL1	0	genome.wustl.edu	37	1	47685497	47685497	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	47685497	47685497	C	T	SNP	TAL1	ENST00000371883	human	ensembl	74_37	-1	known	silent	c.897	p.G299	0.971	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	TAL1	HGNC	ENSG00000162367	tier1	-	-	100	0	0.00	43	7	14.00
TBL2	0	genome.wustl.edu	37	7	72985558	72985558	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	72985558	72985558	G	A	SNP	TBL2	ENST00000305632	human	ensembl	74_37	-1	known	missense	c.839	p.A280V	0.994	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,prints_G-protein_beta_WD-40_rep,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	TBL2	HGNC	ENSG00000106638	tier1	-	-	49	0	0.00	22	24	52.17
TG	0	genome.wustl.edu	37	8	133898746	133898746	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	133898746	133898746	T	G	SNP	TG	ENST00000220616	human	ensembl	74_37	+1	known	missense	c.1129	p.F377V	1.000	pirsf_Thyroglobulin	pfam_Thyroglobulin_1,pfam_CarbesteraseB,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Thyroglobulin_1,smart_Thyroglobulin_1,pirsf_Thyroglobulin,pfscan_Thyroglobulin_1	-	no_errors	TG	HGNC	ENSG00000042832	tier1	-	-	219	0	0.00	111	69	38.33
TGIF2LX	0	genome.wustl.edu	37	X	89177253	89177253	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	X	89177253	89177253	T	A	SNP	TGIF2LX	ENST00000283891	human	ensembl	74_37	+1	known	missense	c.169	p.L57M	0.714	pfam_Homeobox_KN_domain,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_Homeobox_dom,pfam_Homeobox_KN_domain,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	TGIF2LX	HGNC	ENSG00000153779	tier1	-	-	47	0	0.00	9	28	75.68
TLL1	0	genome.wustl.edu	37	4	166915634	166915634	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	166915634	166915634	A	G	SNP	TLL1	ENST00000061240	human	ensembl	74_37	+1	known	missense	c.463	p.R155G	1.000	smart_Peptidase_Metallo,pirsf_BMP_1/tolloid-like	pfam_CUB_dom,pfam_Peptidase_M12A,pfam_EGF-like_Ca-bd_dom,superfamily_CUB_dom,smart_Peptidase_Metallo,smart_CUB_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pirsf_BMP_1/tolloid-like,pfscan_CUB_dom,pfscan_EG-like_dom,prints_Peptidase_M12A	-	no_errors	TLL1	HGNC	ENSG00000038295	tier1	-	-	91	0	0.00	39	20	33.90
TMEM41B	0	genome.wustl.edu	37	11	9305016	9305016	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	9305016	9305016	A	G	SNP	TMEM41B	ENST00000299596	human	ensembl	74_37	-1	known	silent	c.831	p.I277	0.980	NULL	pfam_SNARE_assoc	-	no_errors	TMEM41B	HGNC	ENSG00000166471	tier1	-	-	60	0	0.00	36	4	10.00
TNN	0	genome.wustl.edu	37	1	175046658	175046658	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	1	175046658	175046658	A	C	SNP	TNN	ENST00000239462	human	ensembl	74_37	+1	known	missense	c.104	p.N35T	0.697	NULL	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNN	HGNC	ENSG00000120332	tier1	-	-	84	0	0.00	34	19	35.85
TNS1	0	genome.wustl.edu	37	2	218712303	218712303	+	Silent	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	218712303	218712303	A	C	SNP	TNS1	ENST00000171887	human	ensembl	74_37	-1	known	silent	c.2562	p.T854	0.033	NULL	pfam_PTB,pfam_Tensin_phosphatase_C2-dom,pfam_SH2,superfamily_C2_dom,smart_Tyr_Pase_cat,smart_SH2,smart_PTB/PI_dom,pfscan_SH2,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	TNS1	HGNC	ENSG00000079308	tier1	-	-	125	0	0.00	43	24	35.82
TONSL	0	genome.wustl.edu	37	8	145660506	145660506	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	145660506	145660506	C	T	SNP	TONSL	ENST00000409379	human	ensembl	74_37	-1	known	missense	c.2900	p.R967H	1.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_TPR_repeat,smart_Ankyrin_rpt,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_TPR-contain_dom,prints_Ankyrin_rpt	-	no_errors	TONSL	HGNC	ENSG00000160949				16	0	0.00	8	2	20.00
TP53	0	genome.wustl.edu	37	17	7578530	7578530	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	17	7578530	7578530	A	G	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.400	p.F134L	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	68	0	0.00	3	22	88.00
TRHDE	0	genome.wustl.edu	37	12	73046873	73046873	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	12	73046873	73046873	A	C	SNP	TRHDE	ENST00000261180	human	ensembl	74_37	+1	known	missense	c.2786	p.N929T	1.000	NULL	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	TRHDE	HGNC	ENSG00000072657	tier1	-	-	95	0	0.00	14	30	68.18
TRIM49C	0	genome.wustl.edu	37	11	89774338	89774338	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	89774338	89774338	A	C	SNP	TRIM49C	ENST00000448984	human	ensembl	74_37	+1	known	missense	c.979	p.S327R	0.001	superfamily_ConA-like_lec_gl_sf,prints_Butyrophylin,pfscan_B30.2/SPRY	pfam_SPRY_rcpt,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,superfamily_Lambda_DNA-bd_dom,smart_Znf_RING,smart_Znf_B-box,smart_SPla/RYanodine_receptor_subgr,prints_Butyrophylin,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING	-	no_errors	TRIM49C	HGNC	ENSG00000204449	tier1	-	-	71	0	0.00	33	5	13.16
TRIM49C	0	genome.wustl.edu	37	11	89806425	89806425	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	89806425	89806425	T	A	SNP	TRIM49C	ENST00000432771	human	ensembl	74_37	+1	known	missense	c.1208	p.V403D	0.009	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,pfscan_B30.2/SPRY,prints_Butyrophylin	pfam_SPRY_rcpt,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM49C	HGNC	ENSG00000204449	tier1	-	-	67	0	0.00	14	33	70.21
TRIM51	0	genome.wustl.edu	37	11	55653074	55653074	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	11	55653074	55653074	A	C	SNP	TRIM51	ENST00000449290	human	ensembl	74_37	+1	known	missense	c.170	p.K57T	0.027	NULL	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM51	HGNC	ENSG00000124900	tier1	-	-	37	0	0.00	15	6	28.57
TRIM60	0	genome.wustl.edu	37	4	165961327	165961327	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	4	165961327	165961327	T	G	SNP	TRIM60	ENST00000341062	human	ensembl	74_37	+1	known	missense	c.103	p.F35V	1.000	pfam_Znf_C3HC4_RING-type,smart_Znf_RING,pfscan_Znf_RING	pfam_SPRY_rcpt,pfam_Znf_C3HC4_RING-type,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM60	HGNC	ENSG00000176979	tier1	-	-	104	0	0.00	45	21	31.82
TTN	0	genome.wustl.edu	37	2	179495996	179495996	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	179495996	179495996	T	C	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	silent	c.36075	p.Q12025	1.000	pfam_Ig_I-set,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	43	0	0.00	9	8	47.06
TTN	0	genome.wustl.edu	37	2	179586855	179586855	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	179586855	179586855	T	G	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.18803	p.K6268T	1.000	superfamily_RNaseH-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	255	0	0.00	79	56	41.48
TTN	0	genome.wustl.edu	37	2	179604702	179604702	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	179604702	179604702	T	G	SNP	TTN	ENST00000342175	human	ensembl	74_37	-1	known	silent	c.12745	p.R4249	0.990	superfamily_RNaseH-like_dom	pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	130	0	0.00	38	32	45.71
TUBA3C	0	genome.wustl.edu	37	13	19751191	19751191	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	19751191	19751191	T	G	SNP	TUBA3C	ENST00000400113	human	ensembl	74_37	-1	known	missense	c.932	p.K311T	1.000	pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tub_FtsZ_C,smart_Tubulin/FtsZ_2-layer-sand-dom	pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Delta_tubulin,prints_Beta_tubulin	-	no_errors	TUBA3C	HGNC	ENSG00000198033	tier1	-	-	186	0	0.00	69	54	43.20
UBXN2B	0	genome.wustl.edu	37	8	59346987	59346987	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	59346987	59346987	T	G	SNP	UBXN2B	ENST00000399598	human	ensembl	74_37	+1	known	missense	c.457	p.F153V	1.000	pfam_SEP_domain,superfamily_SEP_domain,smart_SEP_domain	pfam_SEP_domain,pfam_UBX,superfamily_SEP_domain,smart_SEP_domain,smart_UBX,pfscan_UBX	-	no_errors	UBXN2B	HGNC	ENSG00000215114	tier1	-	-	39	0	0.00	22	21	48.84
UTRN	0	genome.wustl.edu	37	6	144758745	144758745	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	144758745	144758745	C	T	SNP	UTRN	ENST00000367545	human	ensembl	74_37	+1	known	silent	c.1104	p.S368	0.001	pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	UTRN	HGNC	ENSG00000152818	tier1	-	-	64	0	0.00	31	12	27.91
UTRN	0	genome.wustl.edu	37	6	144783820	144783820	+	Missense_Mutation	SNP	C	C	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	144783820	144783820	C	A	SNP	UTRN	ENST00000367545	human	ensembl	74_37	+1	known	missense	c.2884	p.P962T	0.815	smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	UTRN	HGNC	ENSG00000152818	tier1	-	-	98	0	0.00	24	22	47.83
VN1R2	0	genome.wustl.edu	37	19	53762234	53762234	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	53762234	53762234	A	C	SNP	VN1R2	ENST00000341702	human	ensembl	74_37	+1	known	missense	c.606	p.K202N	0.003	pfam_Vmron_rcpt_1,pfam_GPCR_Rhodpsn,pfam_TAS2_rcpt,pfscan_GPCR_Rhodpsn_7TM,prints_Vmron_rcpt_1	pfam_Vmron_rcpt_1,pfam_GPCR_Rhodpsn,pfam_TAS2_rcpt,pfscan_GPCR_Rhodpsn_7TM,prints_Vmron_rcpt_1	-	no_errors	VN1R2	HGNC	ENSG00000196131	tier1	-	-	66	0	0.00	27	19	41.30
VWA8	0	genome.wustl.edu	37	13	42306245	42306245	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	13	42306245	42306245	C	T	SNP	VWA8	ENST00000379310	human	ensembl	74_37	-1	known	missense	c.2473	p.G825R	1.000	pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	pfam_ATPase_dyneun-rel_AAA,pfam_VWF_A,superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_VWF_A,pfscan_VWF_A	-	no_errors	VWA8	HGNC	ENSG00000102763	tier1	-	-	85	0	0.00	28	15	34.88
VWC2	0	genome.wustl.edu	37	7	49951712	49951712	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	49951712	49951712	T	G	SNP	VWC2	ENST00000340652	human	ensembl	74_37	+1	known	silent	c.909	p.T303	0.149	NULL	pfam_VWF_C,smart_VWF_C,pfscan_VWF_C	-	no_errors	VWC2	HGNC	ENSG00000188730	tier1	-	-	71	0	0.00	13	13	50.00
WNT2	0	genome.wustl.edu	37	7	116918397	116918397	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	7	116918397	116918397	G	A	SNP	WNT2	ENST00000265441	human	ensembl	74_37	-1	known	missense	c.895	p.R299W	0.999	pfam_Wnt,smart_Wnt	pfam_Wnt,smart_Wnt,prints_Wnt,prints_Wnt2	-	no_errors	WNT2	HGNC	ENSG00000105989				34	0	0.00	33	4	10.81
XDH	0	genome.wustl.edu	37	2	31598295	31598295	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	31598295	31598295	T	G	SNP	XDH	ENST00000379416	human	ensembl	74_37	-1	known	missense	c.1553	p.K518T	1.000	pfam_CO_DH_flav_C,superfamily_CO_DH_flav_C,pirsf_Ald_Oxase/xanthine_DH,tigrfam_Xanthine_DH_ssu	pfam_AldOxase/xan_DH_Mopterin-bd,pfam_Mopterin_DH_FAD-bd,pfam_Ald_Oxase/Xan_DH_a/b,pfam_2Fe-2S-bd,pfam_CO_DH_flav_C,pfam_2Fe-2S_ferredoxin-type,superfamily_AldOxase/xan_DH_Mopterin-bd,superfamily_FAD-bd_2,superfamily_Ald_Oxase/Xan_DH_a/b,superfamily_2Fe-2S-bd,superfamily_CO_DH_flav_C,superfamily_2Fe-2S_ferredoxin-type,pirsf_Ald_Oxase/xanthine_DH,pfscan_2Fe-2S_ferredoxin-type,tigrfam_Xanthine_DH_ssu	-	no_errors	XDH	HGNC	ENSG00000158125	tier1	-	-	134	0	0.00	11	35	76.09
XPA	0	genome.wustl.edu	37	9	100437664	100437664	+	RNA	SNP	C	C	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	9	100437664	100437664	C	G	SNP	XPA	ENST00000485042	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.021	-	-	-	no_errors	XPA	HGNC	ENSG00000136936	tier1	-	-	56	0	0.00	16	14	46.67
ZBBX	0	genome.wustl.edu	37	3	167023579	167023579	+	Missense_Mutation	SNP	A	A	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	3	167023579	167023579	A	C	SNP	ZBBX	ENST00000307529	human	ensembl	74_37	-1	known	missense	c.1577	p.L526R	0.000	NULL	pfam_Znf_B-box	-	no_errors	ZBBX	HGNC	ENSG00000169064	tier1	-	-	105	0	0.00	46	23	33.33
ZFPM2	0	genome.wustl.edu	37	8	106813886	106813886	+	Missense_Mutation	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	8	106813886	106813886	C	T	SNP	ZFPM2	ENST00000407775	human	ensembl	74_37	+1	known	missense	c.1576	p.R526W	0.983	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZFPM2	HGNC	ENSG00000169946	tier1	-	-	157	0	0.00	70	55	44.00
ZNF154	0	genome.wustl.edu	37	19	58213438	58213438	+	Silent	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	58213438	58213438	T	C	SNP	ZNF154	ENST00000426889	human	ensembl	74_37	-1	known	silent	c.879	p.K293	0.934	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF154	HGNC	ENSG00000179909	tier1	-	-	106	0	0.00	49	33	40.24
ZNF280A	0	genome.wustl.edu	37	22	22869567	22869567	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	22	22869567	22869567	G	A	SNP	ZNF280A	ENST00000302097	human	ensembl	74_37	-1	known	missense	c.388	p.P130S	0.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF280A	HGNC	ENSG00000169548	tier1	-	-	99	0	0.00	11	38	77.55
ZNF311	0	genome.wustl.edu	37	6	28963560	28963560	+	Silent	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	6	28963560	28963560	T	G	SNP	ZNF311	ENST00000377179	human	ensembl	74_37	-1	known	silent	c.1219	p.R407	0.650	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF311	HGNC	ENSG00000197935	tier1	-	-	94	0	0.00	46	28	37.84
ZNF347	0	genome.wustl.edu	37	19	53643591	53643591	+	Silent	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	53643591	53643591	G	A	SNP	ZNF347	ENST00000452676	human	ensembl	74_37	-1	known	silent	c.2493	p.F831	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF347	HGNC	ENSG00000197937	tier1	-	-	273	0	0.00	118	64	35.16
ZNF471	0	genome.wustl.edu	37	19	57035783	57035783	+	Missense_Mutation	SNP	T	T	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	57035783	57035783	T	A	SNP	ZNF471	ENST00000308031	human	ensembl	74_37	+1	known	missense	c.347	p.L116H	0.001	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF471	HGNC	ENSG00000196263	tier1	-	-	112	0	0.00	51	35	40.70
ZNF536	0	genome.wustl.edu	37	19	31039381	31039381	+	Missense_Mutation	SNP	T	T	C			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	31039381	31039381	T	C	SNP	ZNF536	ENST00000355537	human	ensembl	74_37	+1	known	missense	c.2855	p.V952A	0.001	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF536	HGNC	ENSG00000198597	tier1	-	-	342	0	0.00	23	73	76.04
ZNF554	0	genome.wustl.edu	37	19	2832480	2832480	+	Missense_Mutation	SNP	G	G	A			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	2832480	2832480	G	A	SNP	ZNF554	ENST00000317243	human	ensembl	74_37	+1	known	missense	c.433	p.A145T	0.002	pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF554	HGNC	ENSG00000172006	tier1	-	-	111	0	0.00	13	25	65.79
ZNF568	0	genome.wustl.edu	37	19	37488342	37488342	+	Silent	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	37488342	37488342	A	G	SNP	ZNF568	ENST00000455427	human	ensembl	74_37	+1	known	silent	c.1557	p.K519	0.395	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF568	HGNC	ENSG00000198453	tier1	-	-	17	0	0.00	7	8	53.33
ZNF729	0	genome.wustl.edu	37	19	22499083	22499083	+	Missense_Mutation	SNP	A	A	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	22499083	22499083	A	T	SNP	ZNF729	ENST00000601693	human	ensembl	74_37	+1	novel	missense	c.2864	p.K955M	0.880	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF729	HGNC	ENSG00000196350	tier1	-	-	83	0	0.00	15	19	55.88
ZNF793	0	genome.wustl.edu	37	19	38027931	38027931	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	38027931	38027931	T	G	SNP	ZNF793	ENST00000445217	human	ensembl	74_37	+1	known	missense	c.371	p.L124R	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF793	HGNC	ENSG00000188227	tier1	-	-	33	0	0.00	12	9	42.86
ZNF804A	0	genome.wustl.edu	37	2	185801789	185801789	+	Missense_Mutation	SNP	A	A	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	2	185801789	185801789	A	G	SNP	ZNF804A	ENST00000302277	human	ensembl	74_37	+1	known	missense	c.1666	p.R556G	0.149	NULL	pfam_Znf_C2H2_jaz	-	no_errors	ZNF804A	HGNC	ENSG00000170396	tier1	-	-	84	0	0.00	31	21	40.38
ZNF813	0	genome.wustl.edu	37	19	53995165	53995165	+	Missense_Mutation	SNP	T	T	G			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	53995165	53995165	T	G	SNP	ZNF813	ENST00000396403	human	ensembl	74_37	+1	known	missense	c.1679	p.F560C	0.427	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF813	HGNC	ENSG00000198346	tier1	-	-	104	0	0.00	28	19	40.43
ZSCAN1	0	genome.wustl.edu	37	19	58565272	58565272	+	Silent	SNP	C	C	T			TCGA-VQ-A91V-01A-11D-A410-08	TCGA-VQ-A91V-10B-01D-A413-08	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	129bd509-0f0a-48e8-91e6-e676d87e47d4	0814f8b7-c702-4acd-9d6b-c846eb21428f	19	58565272	58565272	C	T	SNP	ZSCAN1	ENST00000282326	human	ensembl	74_37	+1	known	silent	c.1080	p.S360	0.004	NULL	pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN1	HGNC	ENSG00000152467	tier1	rs144381428	-	31	0	0.00	7	5	41.67
