Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
LOC645752	645752	broad.mit.edu	37	15	78213945	78213945	+	RNA	SNP	T	T	C			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr15:78213945T>C	ENST00000565869.1	+	0	111				RP11-114H24.2_ENST00000567226.1_RNA																							CCTTTTCCAATGTGAGGATGT	0.478000													7	85					0	0	1	0	0
EPB41L2	2037	broad.mit.edu	37	6	131186732	131186732	+	Missense_Mutation	SNP	C	C	T	rs61731764	byFrequency	TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr6:131186732C>T	ENST00000337057.3	-	17	2954	c.2773G>A	c.(2773-2775)Gca>Aca	p.A925T	EPB41L2_ENST00000530757.1_Intron|EPB41L2_ENST00000524581.1_Missense_Mutation_p.A303T|EPB41L2_ENST00000531410.1_Missense_Mutation_p.A46T|EPB41L2_ENST00000528282.1_Missense_Mutation_p.A667T|EPB41L2_ENST00000525271.1_Intron|EPB41L2_ENST00000445890.2_Missense_Mutation_p.A667T|EPB41L2_ENST00000527411.1_Missense_Mutation_p.A855T|EPB41L2_ENST00000525193.1_Missense_Mutation_p.A626T|EPB41L2_ENST00000368128.2_Missense_Mutation_p.A925T|EPB41L2_ENST00000527659.1_Missense_Mutation_p.A731T|EPB41L2_ENST00000529208.1_Missense_Mutation_p.A855T|EPB41L2_ENST00000530481.1_Missense_Mutation_p.A772T|EPB41L2_ENST00000392427.3_Intron	NM_001431.3	NP_001422.1	O43491	E41L2_HUMAN	erythrocyte membrane protein band 4.1-like 2	925	Carboxyl-terminal (CTD).				cortical actin cytoskeleton organization	extrinsic to membrane|plasma membrane|spectrin	actin binding|structural molecule activity			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(7)|kidney(2)|large_intestine(7)|lung(23)|prostate(1)|skin(2)	44	Breast(56;0.0639)			OV - Ovarian serous cystadenocarcinoma(155;0.0271)|GBM - Glioblastoma multiforme(226;0.0355)		ATGGTTTGTGCGGTCAGTAAC	0.458000													4	93					0	0	1	0	0
ANKRD20A8P	729171	broad.mit.edu	37	2	95522772	95522772	+	RNA	SNP	T	T	C			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr2:95522772T>C	ENST00000432432.2	-	0	255					NR_040113.1													p.E49G(1)									GCGCTCCACCTCCGCGGCGTC	0.682000													3	38					0	0	1	0	0
PAX2	5076	broad.mit.edu	37	10	102510501	102510501	+	Missense_Mutation	SNP	C	C	A			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr10:102510501C>A	ENST00000370296.2	+	3	813	c.263C>A	c.(262-264)cCc>cAc	p.P88H	PAX2_ENST00000556085.1_Missense_Mutation_p.P87H|PAX2_ENST00000361791.3_Missense_Mutation_p.P88H|PAX2_ENST00000355243.3_Missense_Mutation_p.P88H|PAX2_ENST00000428433.1_Missense_Mutation_p.P88H|PAX2_ENST00000553492.1_Intron			Q02962	PAX2_HUMAN	paired box 2	88	Paired.				anti-apoptosis|axonogenesis|brain morphogenesis|branching involved in ureteric bud morphogenesis|cell fate determination|cellular response to glucose stimulus|cellular response to hydrogen peroxide|cellular response to retinoic acid|cochlea development|glial cell differentiation|inner ear morphogenesis|mesenchymal to epithelial transition involved in metanephros morphogenesis|mesodermal cell fate specification|mesonephros development|metanephric collecting duct development|metanephric distal convoluted tubule development|metanephric mesenchymal cell differentiation|metanephric nephron tubule formation|negative regulation of caspase activity|negative regulation of cytolysis|negative regulation of mesenchymal stem cell apoptosis involved in metanephric nephron morphogenesis|negative regulation of reactive oxygen species metabolic process|negative regulation of transcription, DNA-dependent|nephric duct formation|neural tube closure|optic chiasma development|optic cup morphogenesis involved in camera-type eye development|optic nerve structural organization|positive regulation of branching involved in ureteric bud morphogenesis|positive regulation of epithelial cell proliferation|positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis|positive regulation of metanephric DCT cell differentiation|positive regulation of metanephric glomerulus development|positive regulation of optic nerve formation|positive regulation of transcription from RNA polymerase II promoter|pronephric field specification|protein kinase B signaling cascade|reactive oxygen species metabolic process|regulation of metanephric nephron tubule epithelial cell differentiation|regulation of metanephros size|retinal pigment epithelium development|stem cell differentiation|transcription from RNA polymerase II promoter|ureter maturation|vestibulocochlear nerve formation|visual perception	centriolar satellite|nucleus|protein complex|protein-DNA complex	core promoter proximal region sequence-specific DNA binding|superoxide-generating NADPH oxidase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(10)|prostate(1)|upper_aerodigestive_tract(1)	18		Colorectal(252;0.234)		Epithelial(162;1.32e-08)|all cancers(201;7.32e-07)		GGCTCCAAGCCCAAAGTGGCG	0.627000													3	67					0.004672	0.00491789	1	1	0
TGFBI	7045	broad.mit.edu	37	5	135390519	135390519	+	Missense_Mutation	SNP	G	G	A			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr5:135390519G>A	ENST00000442011.2	+	10	1540	c.1379G>A	c.(1378-1380)gGc>gAc	p.G460D	TGFBI_ENST00000305126.8_Missense_Mutation_p.G460D	NM_000358.2	NP_000349.1	Q15582	BGH3_HUMAN	transforming growth factor, beta-induced, 68kDa	460	FAS1 3.				angiogenesis|cell adhesion|cell proliferation|negative regulation of cell adhesion|response to stimulus|visual perception	extracellular space|proteinaceous extracellular matrix	integrin binding	p.G460D(1)		breast(6)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(2)|lung(8)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	32			KIRC - Kidney renal clear cell carcinoma(527;0.0101)|Kidney(363;0.0233)			ACTCTGGGCGGCAAAAAACTG	0.423000													4	189					0	0	1	0	0
LRRC37A4P	55073	broad.mit.edu	37	17	43587730	43587730	+	RNA	SNP	A	A	C	rs142536398	by1000genomes	TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr17:43587730A>C	ENST00000253803.2	+	0	267				LRRC37A4P_ENST00000579913.1_RNA																							GTATTGATTCATTTTATTCAT	0.343000													3	12					0	0	1	0	0
LOC220729	220729	broad.mit.edu	37	3	197348674	197348674	+	RNA	SNP	A	A	G	rs144273946	by1000genomes	TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr3:197348674A>G	ENST00000418868.1	-	0	585					NR_003266.2																						GGCTCTGTCCACCAAATGCAC	0.478000													3	81					0	0	1	0	0
SMURF2	64750	broad.mit.edu	37	17	62568009	62568009	+	Missense_Mutation	SNP	G	G	A			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr17:62568009G>A	ENST00000262435.9	-	10	1110	c.923C>T	c.(922-924)aCg>aTg	p.T308M	SMURF2_ENST00000578200.1_Intron	NM_022739.3	NP_073576.1	Q9HAU4	SMUF2_HUMAN	SMAD specific E3 ubiquitin protein ligase 2	308	WW 3.				BMP signaling pathway|negative regulation of transcription, DNA-dependent|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of transforming growth factor beta receptor signaling pathway|transforming growth factor beta receptor signaling pathway|ubiquitin-dependent SMAD protein catabolic process	cytosol|membrane raft|nucleus|plasma membrane|ubiquitin ligase complex	identical protein binding|SMAD binding|ubiquitin-protein ligase activity			breast(2)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(2)|lung(6)|prostate(1)|skin(4)	22	Breast(5;1.32e-14)		BRCA - Breast invasive adenocarcinoma(8;9.88e-12)			GCCTGTTGCCGTATTACGGAT	0.378000													3	31					0	0	1	0	0
ANKRD20A8P	729171	broad.mit.edu	37	2	95522786	95522786	+	RNA	SNP	T	T	C			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr2:95522786T>C	ENST00000432432.2	-	0	241					NR_040113.1													p.K44K(1)									CGGCGTCGCCTTTGACAGCTG	0.687000													4	43					0	0	1	0	0
ANKRD20A8P	729171	broad.mit.edu	37	2	95522815	95522815	+	RNA	SNP	A	A	G			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr2:95522815A>G	ENST00000432432.2	-	0	212					NR_040113.1																						ATCTTCTGCAATTCGGAGTCC	0.652000													3	44					0	0	1	0	0
HYDIN	54768	broad.mit.edu	37	16	70954659	70954659	+	Silent	SNP	T	T	C			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr16:70954659T>C	ENST00000393567.2	-	46	7770	c.7620A>G	c.(7618-7620)cgA>cgG	p.R2540R		NM_001270974.1	NP_001257903.1	Q4G0P3	HYDIN_HUMAN	HYDIN, axonemal central pair apparatus protein	2540										breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(17)|lung(12)|ovary(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)	43		Ovarian(137;0.0654)				cctccagggctcgcagcttct	0.667000													4	7					0	0	1	0	0
LILRB4	11006	broad.mit.edu	37	19	55179342	55179342	+	Missense_Mutation	SNP	C	C	T			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr19:55179342C>T	ENST00000391736.1	+	14	1534	c.1219C>T	c.(1219-1221)Ccc>Tcc	p.P407S	LILRB4_ENST00000391734.3_Missense_Mutation_p.P354S|LILRB4_ENST00000270452.2_Missense_Mutation_p.P407S|LILRB4_ENST00000391733.3_Missense_Mutation_p.P408S|LILRB4_ENST00000430952.2_Missense_Mutation_p.P406S	NM_001278426.2|NM_001278428.2|NM_001278429.2|NM_001278430.2	NP_001265355.1|NP_001265357.1|NP_001265358.1|NP_001265359.1	Q8NHJ6	LIRB4_HUMAN	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	407						integral to membrane|plasma membrane	antigen binding|receptor activity	p.P407S(1)		breast(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(4)|lung(20)|ovary(3)|skin(1)|stomach(2)|upper_aerodigestive_tract(3)	39				GBM - Glioblastoma multiforme(193;0.035)		ATCTGAAGCCCCCCAGGATGT	0.647000													4	44					0	0	1	0	0
RP11-597A11.1	0	broad.mit.edu	37	14	20086237	20086237	+	RNA	DEL	T	T	-			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr14:20086237delT	ENST00000548261.1	+	0	51																											GGTGTGTGTGTGGGGGGGTAT	0.388													4	3	---	---	---	---					
LILRB4	11006	broad.mit.edu	37	19	55179244	55179244	+	Splice_Site	DEL	G	G	-			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr19:55179244delG	ENST00000391736.1	+	13	1515	c.1200delG	c.(1198-1200)gag>ga	p.E400fs	LILRB4_ENST00000391734.3_Intron|LILRB4_ENST00000270452.2_Splice_Site_p.E400fs|LILRB4_ENST00000430952.2_Splice_Site_p.E399fs|LILRB4_ENST00000391733.3_Splice_Site_p.E401fs	NM_001278426.2|NM_001278428.2|NM_001278429.2|NM_001278430.2	NP_001265355.1|NP_001265357.1|NP_001265358.1|NP_001265359.1	Q8NHJ6	LIRB4_HUMAN	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	400						integral to membrane|plasma membrane	antigen binding|receptor activity			breast(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(4)|lung(20)|ovary(3)|skin(1)|stomach(2)|upper_aerodigestive_tract(3)	39				GBM - Glioblastoma multiforme(193;0.035)		TGGACACTGAGGTGAGTCCTT	0.617													9	17	---	---	---	---					
FAM83D	81610	broad.mit.edu	37	20	37555322	37555323	+	In_Frame_Ins	INS	-	-	GCG			TCGA-XF-AAN8-01A-11D-A42E-08	TCGA-XF-AAN8-10A-01D-A42H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	149cff48-9318-46f3-9cae-2258bf2e592d	37b82f2a-acca-4974-9e23-36d71784878e	g.chr20:37555322_37555323insGCG	ENST00000217429.4	+	1	368_369	c.327_328insGCG	c.(328-330)gcg>GCGgcg	p.110_110A>AA		NM_030919.2	NP_112181.2	Q9H4H8	FA83D_HUMAN	family with sequence similarity 83, member D	80					cell division|mitosis	cytoplasm|spindle pole				endometrium(2)|kidney(2)|large_intestine(7)|lung(12)|ovary(4)|stomach(1)	28		Myeloproliferative disorder(115;0.00878)				GAGAGGAGGGCgcggcggcggc	0.718													4	5	---	---	---	---					
