Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
STX6	10228	broad.mit.edu	37	1	180974535	180974535	+	Missense_Mutation	SNP	C	C	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr1:180974535C>A	ENST00000258301.5	-	2	337	c.100G>T	c.(100-102)Gac>Tac	p.D34Y	STX6_ENST00000542060.1_Intron	NM_005819.4	NP_005810.1	O43752	STX6_HUMAN	syntaxin 6	34					Golgi vesicle transport|intracellular protein transport|vesicle fusion	clathrin-coated vesicle|early endosome|integral to membrane|perinuclear region of cytoplasm|plasma membrane|trans-Golgi network membrane	SNAP receptor activity			breast(1)|central_nervous_system(1)|endometrium(3)|large_intestine(2)|lung(1)|ovary(1)|prostate(1)	10						GTGGAGGGGTCCTGGAGGAGC	0.498000													7	63					0.000157383	0.000161755	1	1	0
CD2BP2	10421	broad.mit.edu	37	16	30365641	30365641	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr16:30365641C>T	ENST00000305596.3	-	3	256	c.81G>A	c.(79-81)ctG>ctA	p.L27L	CD2BP2_ENST00000569466.1_Silent_p.L27L	NM_006110.2	NP_006101.1	O95400	CD2B2_HUMAN	CD2 (cytoplasmic tail) binding protein 2	27					assembly of spliceosomal tri-snRNP	cytoplasm|nucleoplasm|U5 snRNP	protein binding|ribonucleoprotein binding			breast(1)|large_intestine(4)|lung(8)|ovary(1)|skin(1)	15						CAGGGTCCACCAGCTGTGAGC	0.527000													12	169					0	0	1	0	0
TOX3	27324	broad.mit.edu	37	16	52497974	52497974	+	Missense_Mutation	SNP	G	G	C			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr16:52497974G>C	ENST00000219746.9	-	3	564	c.280C>G	c.(280-282)Cca>Gca	p.P94A	TOX3_ENST00000407228.3_Missense_Mutation_p.P89A	NM_001080430.2	NP_001073899.2	O15405	TOX3_HUMAN	TOX high mobility group box family member 3	94					apoptosis|negative regulation of neuron apoptosis|positive regulation of anti-apoptosis|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	chromatin binding|estrogen response element binding|phosphoprotein binding|protein homodimerization activity			NS(2)|endometrium(6)|kidney(1)|lung(8)|prostate(3)|stomach(3)|upper_aerodigestive_tract(1)	24						GAAGGCAATGGATCGCTGAGG	0.532000													4	49					0	0	1	0	0
DCAF8	50717	broad.mit.edu	37	1	160209906	160209906	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr1:160209906C>T	ENST00000368073.3	-	4	738	c.304G>A	c.(304-306)Gag>Aag	p.E102K	DCAF8_ENST00000326837.2_Missense_Mutation_p.E102K|DCAF8_ENST00000610139.1_Missense_Mutation_p.E102K|DCAF8_ENST00000556710.1_Missense_Mutation_p.E256K|DCAF8_ENST00000475733.1_Missense_Mutation_p.E102K|DCAF8_ENST00000608310.1_Missense_Mutation_p.E256K|DCAF8_ENST00000368074.1_Missense_Mutation_p.E102K			Q5TAQ9	DCAF8_HUMAN	DDB1 and CUL4 associated factor 8	102						CUL4 RING ubiquitin ligase complex	protein binding			cervix(1)|endometrium(4)|kidney(2)|large_intestine(6)|lung(16)|skin(3)|upper_aerodigestive_tract(1)	33						tcctcttcctcttcctctGAG	0.537000													3	22					0	0	1	0	0
CD101	9398	broad.mit.edu	37	1	117552712	117552712	+	Missense_Mutation	SNP	A	A	G			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr1:117552712A>G	ENST00000256652.4	+	2	342	c.284A>G	c.(283-285)tAc>tGc	p.Y95C	CD101_ENST00000369470.1_Missense_Mutation_p.Y95C	NM_001256106.1|NM_001256109.1|NM_001256111.1|NM_004258.4	NP_001243035.1|NP_001243038.1|NP_001243040.1|NP_004249.2	Q93033	IGSF2_HUMAN	CD101 molecule	95	Ig-like C2-type 1.				cell surface receptor linked signaling pathway	integral to membrane|plasma membrane	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides			NS(1)|breast(1)|endometrium(6)|kidney(3)|large_intestine(14)|lung(18)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	49						GGAGACGTCTACGTGGAGAGG	0.532000													3	34					0	0	1	0	0
C11orf88	399949	broad.mit.edu	37	11	111386809	111386809	+	Missense_Mutation	SNP	G	G	C			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr11:111386809G>C	ENST00000529167.1	+	3	313	c.313G>C	c.(313-315)Gag>Cag	p.E105Q	C11orf88_ENST00000332814.6_Missense_Mutation_p.E105Q|RP11-794P6.6_ENST00000530283.1_RNA|C11orf88_ENST00000375618.4_Missense_Mutation_p.E105Q			Q6PI97	CK088_HUMAN	chromosome 11 open reading frame 88	105										endometrium(1)|large_intestine(3)|lung(2)	6						ACAGGAATCTGAGGAGAAAGT	0.294000													4	32					0	0	1	0	0
MAP7D2	256714	broad.mit.edu	37	X	20043941	20043941	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chrX:20043941C>T	ENST00000379651.3	-	8	1032	c.1014G>A	c.(1012-1014)aaG>aaA	p.K338K	MAP7D2_ENST00000543767.1_Silent_p.K223K|MAP7D2_ENST00000443379.3_Silent_p.K293K|MAP7D2_ENST00000452324.3_Silent_p.K286K|MAP7D2_ENST00000466145.1_5'UTR|MAP7D2_ENST00000379643.5_Silent_p.K379K	NM_152780.3	NP_689993.2	Q96T17	MA7D2_HUMAN	MAP7 domain containing 2	338										NS(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(9)|lung(13)|ovary(2)|prostate(1)|upper_aerodigestive_tract(1)	37						CCTTGTTGCTCTTCTCTTTCT	0.552000													6	74					0	0	1	0	0
ATP6V0B	533	broad.mit.edu	37	1	44442930	44442930	+	Silent	SNP	A	A	G	rs2428954	by1000genomes	TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr1:44442930A>G	ENST00000532642.1	+	7	730	c.633A>G	c.(631-633)caA>caG	p.Q211Q	ATP6V0B_ENST00000471859.2_Intron|ATP6V0B_ENST00000236067.4_Intron|ATP6V0B_ENST00000472174.2_Intron|ATP6V0B_ENST00000498664.1_Intron			Q99437	VATO_HUMAN	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	110					ATP hydrolysis coupled proton transport|cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport	endosome membrane|integral to membrane|proton-transporting V-type ATPase, V0 domain|vacuolar membrane	hydrogen ion transmembrane transporter activity			breast(2)|kidney(1)|large_intestine(3)|lung(3)	9	Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0511)				CTTGTCCCCAACCTAGCCTTA	0.512000													3	28					0	0	1	0	0
ZNF511	118472	broad.mit.edu	37	10	135125450	135125450	+	Missense_Mutation	SNP	G	G	C			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr10:135125450G>C	ENST00000359035.3	+	5	788	c.785G>C	c.(784-786)aGg>aCg	p.R262T	ZNF511_ENST00000361518.5_Intron|ZNF511_ENST00000368554.4_Intron|ZNF511_ENST00000463816.2_Intron			Q8NB15	ZN511_HUMAN	zinc finger protein 511	262					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			cervix(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(2)|ovary(1)	8		all_cancers(35;7.01e-07)|all_epithelial(44;1.45e-05)|Lung NSC(174;0.027)|all_lung(145;0.0384)|all_neural(114;0.0726)|Glioma(114;0.172)|Melanoma(40;0.175)		all cancers(32;7.56e-06)|OV - Ovarian serous cystadenocarcinoma(35;8.15e-06)|Epithelial(32;9.99e-06)		AATTCAGAAAGGTAACGCTGG	0.478000													3	27					0	0	1	0	0
POLR1A	25885	broad.mit.edu	37	2	86254638	86254638	+	Missense_Mutation	SNP	C	C	T	rs74900877		TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr2:86254638C>T	ENST00000263857.6	-	34	5449	c.5071G>A	c.(5071-5073)Gat>Aat	p.D1691N	POLR1A_ENST00000409681.1_Missense_Mutation_p.D1630N			O95602	RPA1_HUMAN	polymerase (RNA) I polypeptide A, 194kDa	1691					termination of RNA polymerase I transcription|transcription elongation from RNA polymerase I promoter|transcription initiation from RNA polymerase I promoter	DNA-directed RNA polymerase I complex|nucleoplasm	DNA binding|DNA-directed RNA polymerase activity|protein binding|zinc ion binding			NS(1)|breast(4)|cervix(2)|endometrium(8)|kidney(3)|large_intestine(12)|liver(1)|lung(20)|ovary(3)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(5)	63						CTCAGCTCATCGTGGGATCCT	0.552000													7	71					0	0	1	0	0
BMP7	655	broad.mit.edu	37	20	55803330	55803330	+	Missense_Mutation	SNP	G	G	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr20:55803330G>A	ENST00000395863.3	-	2	1071	c.566C>T	c.(565-567)aCg>aTg	p.T189M	BMP7_ENST00000450594.2_Missense_Mutation_p.T189M|BMP7_ENST00000395864.3_Missense_Mutation_p.T189M	NM_001719.2	NP_001710.1	P18075	BMP7_HUMAN	bone morphogenetic protein 7	189					BMP signaling pathway|cartilage development|cellular response to hypoxia|epithelial to mesenchymal transition|growth|mesonephros development|negative regulation of glomerular mesangial cell proliferation|negative regulation of MAP kinase activity|negative regulation of mitosis|negative regulation of neuron differentiation|negative regulation of NF-kappaB import into nucleus|negative regulation of NF-kappaB transcription factor activity|negative regulation of phosphorylation|negative regulation of striated muscle cell apoptosis|negative regulation of transcription, DNA-dependent|ossification|pathway-restricted SMAD protein phosphorylation|positive regulation of bone mineralization|positive regulation of osteoblast differentiation|positive regulation of pathway-restricted SMAD protein phosphorylation|protein localization to nucleus|regulation of removal of superoxide radicals|SMAD protein signal transduction|steroid hormone mediated signaling pathway|ureteric bud development	extracellular space	cytokine activity|growth factor activity			endometrium(4)|kidney(1)|large_intestine(7)|lung(6)|prostate(1)|skin(1)	20	all_lung(29;0.0133)|Melanoma(10;0.242)		BRCA - Breast invasive adenocarcinoma(4;2.49e-13)|Epithelial(14;1.74e-08)|all cancers(14;2.05e-07)			GATCCGGAACGTCTCATTGTC	0.557000													13	134					0	0	1	0	0
DDB2	1643	broad.mit.edu	37	11	47256319	47256319	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr11:47256319C>T	ENST00000256996.4	+	6	909	c.714C>T	c.(712-714)ctC>ctT	p.L238L	DDB2_ENST00000378601.3_Intron|DDB2_ENST00000378600.3_Intron|DDB2_ENST00000378603.3_Silent_p.L174L	NM_000107.2	NP_000098.1	Q92466	DDB2_HUMAN	damage-specific DNA binding protein 2, 48kDa	238					nucleotide-excision repair, DNA damage removal|protein autoubiquitination|protein polyubiquitination|response to UV	nucleoplasm|protein complex	damaged DNA binding|protein binding			breast(1)|endometrium(2)|kidney(2)|large_intestine(3)|lung(6)|ovary(1)|prostate(1)|skin(1)	17						TTTGGAATCTCAGAATGCACA	0.542000			"""Mis, N"""			"""skin basal cell, skin squamous cell, melanoma"""		Direct reversal of damage;Nucleotide excision repair (NER)	Xeroderma Pigmentosum				3	28					0	0	1	0	0
POSTN	10631	broad.mit.edu	37	13	38143931	38143931	+	Missense_Mutation	SNP	G	G	C			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr13:38143931G>C	ENST00000379747.4	-	20	2414	c.2297C>G	c.(2296-2298)tCt>tGt	p.S766C	POSTN_ENST00000541179.1_Missense_Mutation_p.S739C|POSTN_ENST00000379749.4_Missense_Mutation_p.S766C|POSTN_ENST00000379743.4_Missense_Mutation_p.S739C|POSTN_ENST00000541481.1_Missense_Mutation_p.S679C|POSTN_ENST00000497145.1_5'UTR|POSTN_ENST00000379742.4_Missense_Mutation_p.S709C	NM_006475.2	NP_006466.2	Q15063	POSTN_HUMAN	periostin, osteoblast specific factor	766					cell adhesion|skeletal system development	proteinaceous extracellular matrix	heparin binding			cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(16)|lung(22)|ovary(2)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	59		Lung NSC(96;2.09e-05)|Prostate(109;0.0513)|Breast(139;0.0538)|Lung SC(185;0.0743)		all cancers(112;2.48e-08)|Epithelial(112;2.78e-06)|OV - Ovarian serous cystadenocarcinoma(117;0.000853)|BRCA - Breast invasive adenocarcinoma(63;0.013)|GBM - Glioblastoma multiforme(144;0.0154)		ACCTCCAGTAGAAATCCTAGT	0.368000													4	27					0	0	1	0	0
FASTKD5	60493	broad.mit.edu	37	20	3127437	3127437	+	Silent	SNP	G	G	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr20:3127437G>A	ENST00000380266.3	-	2	2601	c.2280C>T	c.(2278-2280)ttC>ttT	p.F760F	UBOX5-AS1_ENST00000446537.1_RNA|UBOX5_ENST00000348031.2_Intron|UBOX5_ENST00000217173.2_Intron	NM_021826.4	NP_068598.1	Q7L8L6	FAKD5_HUMAN	FAST kinase domains 5	760					apoptosis|cellular respiration	mitochondrion	ATP binding|protein kinase activity			breast(2)|endometrium(2)|large_intestine(2)|lung(8)|prostate(2)|skin(1)|urinary_tract(2)	19						GAGCAGAGGTGAATACTTTCT	0.438000													8	101					0	0	1	0	0
RHOD	29984	broad.mit.edu	37	11	66837937	66837937	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr11:66837937C>T	ENST00000308831.2	+	4	457	c.372C>T	c.(370-372)atC>atT	p.I124I	RHOD_ENST00000533360.1_3'UTR|RHOD_ENST00000532559.1_Silent_p.I58I	NM_014578.3	NP_055393	O00212	RHOD_HUMAN	ras homolog family member D	124					regulation of small GTPase mediated signal transduction|Rho protein signal transduction	cytosol|plasma membrane	GTP binding|GTPase activity			lung(3)	3						AGGTACCCATCATCGTCGTGG	0.567000													4	61					0	0	1	0	0
ZFP41	286128	broad.mit.edu	37	8	144332417	144332417	+	Missense_Mutation	SNP	G	G	C			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr8:144332417G>C	ENST00000330701.4	+	2	773	c.404G>C	c.(403-405)aGg>aCg	p.R135T	ZFP41_ENST00000520584.1_Missense_Mutation_p.R135T|ZFP41_ENST00000522452.1_Missense_Mutation_p.R135T	NM_173832.4	NP_776193.1	Q8N8Y5	ZFP41_HUMAN	ZFP41 zinc finger protein	135					cell differentiation|multicellular organismal development|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(2)|lung(4)|ovary(1)	8	all_cancers(97;1.01e-10)|all_epithelial(106;4.6e-09)|Lung NSC(106;0.000167)|all_lung(105;0.000459)|Ovarian(258;0.0212)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.156)|Colorectal(110;0.173)			AAACACCAGAGGACTCACACG	0.582000													8	120					0	0	1	0	0
SLC22A1	6580	broad.mit.edu	37	6	160564643	160564643	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr6:160564643C>T	ENST00000366963.4	+	8	1494	c.1347C>T	c.(1345-1347)atC>atT	p.I449I	SLC22A1_ENST00000324965.4_Silent_p.I449I|SLC22A1_ENST00000457470.2_Silent_p.I449I	NM_003057.2|NM_153187.1	NP_003048.1|NP_694857.1	O15245	S22A1_HUMAN	solute carrier family 22 (organic cation transporter), member 1	449						basolateral plasma membrane|integral to plasma membrane|membrane fraction	organic cation transmembrane transporter activity|protein binding		SLC22A1/CUTA(2)	breast(1)|endometrium(3)|large_intestine(3)|lung(13)|upper_aerodigestive_tract(1)	21		Breast(66;0.000776)|Ovarian(120;0.00556)		OV - Ovarian serous cystadenocarcinoma(65;2.73e-17)|BRCA - Breast invasive adenocarcinoma(81;1.1e-06)		TACAAATGATCTGCCTGGTGA	0.498000													4	50					0	0	1	0	0
PLEKHG6	55200	broad.mit.edu	37	12	6436877	6436877	+	Missense_Mutation	SNP	G	G	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr12:6436877G>A	ENST00000449001.2	+	14	2526	c.2032G>A	c.(2032-2034)Gag>Aag	p.E678K	PLEKHG6_ENST00000396988.3_Missense_Mutation_p.E710K|PLEKHG6_ENST00000011684.7_Missense_Mutation_p.E710K|PLEKHG6_ENST00000304581.8_Missense_Mutation_p.E240K	NM_001144857.1	NP_001138329.1	Q3KR16	PKHG6_HUMAN	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	710					regulation of Rho protein signal transduction	cleavage furrow|cytoplasm|spindle pole	GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|kidney(3)|large_intestine(4)|lung(6)|ovary(1)|prostate(2)|skin(4)	23						AAGCCCCTGGGAGTCCTCAGG	0.642000													3	24					0	0	1	0	0
ASAH1	427	broad.mit.edu	37	8	17920698	17920698	+	Missense_Mutation	SNP	G	G	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr8:17920698G>A	ENST00000262097.6	-	7	810	c.499C>T	c.(499-501)Ctt>Ttt	p.L167F	ASAH1_ENST00000417108.2_Missense_Mutation_p.L77F|ASAH1_ENST00000381733.4_Missense_Mutation_p.L183F|ASAH1_ENST00000520781.1_Missense_Mutation_p.L142F|ASAH1_ENST00000314146.10_Missense_Mutation_p.L161F	NM_177924.3	NP_808592.2	Q13510	ASAH1_HUMAN	N-acylsphingosine amidohydrolase (acid ceramidase) 1	167					ceramide metabolic process	lysosome	ceramidase activity			breast(1)|endometrium(2)|large_intestine(4)|lung(2)	9				Colorectal(111;0.0646)|COAD - Colon adenocarcinoma(73;0.228)		ACTTACCCAAGAAATACTCCA	0.438000													16	198					0	0	1	0	0
KLRB1	3820	broad.mit.edu	37	12	9760381	9760381	+	Missense_Mutation	SNP	C	C	T	rs144231382	byFrequency	TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr12:9760381C>T	ENST00000229402.3	-	1	101	c.55G>A	c.(55-57)Gaa>Aaa	p.E19K		NM_002258.2	NP_002249.1	Q12918	KLRB1_HUMAN	killer cell lectin-like receptor subfamily B, member 1	19					cell surface receptor linked signaling pathway	integral to membrane|plasma membrane	sugar binding|transmembrane receptor activity			endometrium(2)|large_intestine(6)|lung(4)	12						GAAGAACTTTCTGGGCCTGAG	0.413000													7	47					0	0	1	0	0
DNM1P47	100216544	broad.mit.edu	37	15	102292785	102292785	+	RNA	SNP	C	C	G	rs61084368		TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr15:102292785C>G	ENST00000561463.1	+	0	831																		p.Q125E(1)									TGCTGCTTCTCAGAGCTGCTG	0.602000													3	20					0	0	1	0	0
HIVEP2	3097	broad.mit.edu	37	6	143093208	143093208	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr6:143093208C>T	ENST00000367603.2	-	5	3410	c.2668G>A	c.(2668-2670)Gag>Aag	p.E890K	HIVEP2_ENST00000367604.1_Missense_Mutation_p.E890K|HIVEP2_ENST00000012134.2_Missense_Mutation_p.E890K	NM_006734.3	NP_006725.3	P31629	ZEP2_HUMAN	human immunodeficiency virus type I enhancer binding protein 2	890					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|breast(4)|central_nervous_system(6)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(19)|lung(35)|ovary(4)|prostate(6)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	100				OV - Ovarian serous cystadenocarcinoma(155;1.61e-05)|GBM - Glioblastoma multiforme(68;0.0102)		ACTCGAATCTCAGGAACCTGG	0.547000													3	31					0	0	1	0	0
RB1CC1	9821	broad.mit.edu	37	8	53570635	53570635	+	Missense_Mutation	SNP	G	G	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr8:53570635G>T	ENST00000025008.5	-	14	2366	c.1843C>A	c.(1843-1845)Cta>Ata	p.L615I	RB1CC1_ENST00000435644.2_Missense_Mutation_p.L615I|RB1CC1_ENST00000539297.1_Missense_Mutation_p.L615I|RB1CC1_ENST00000521611.1_Intron	NM_014781.4	NP_055596.3	Q8TDY2	RBCC1_HUMAN	RB1-inducible coiled-coil 1	615					autophagy|cell cycle|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nucleus|pre-autophagosomal structure|ULK1-ATG13-FIP200 complex	protein binding			NS(2)|cervix(2)|endometrium(6)|kidney(4)|large_intestine(9)|lung(19)|ovary(8)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(2)	60		all_cancers(86;0.137)|all_epithelial(80;0.00494)|Lung NSC(129;0.011)|all_lung(136;0.023)				AAATTATGTAGAGCAAGTACA	0.358000													4	41					0.00024832	0.00024832	1	1	0
SERPINE1	5054	broad.mit.edu	37	7	100775224	100775224	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr7:100775224C>T	ENST00000223095.4	+	4	731	c.574C>T	c.(574-576)Ctc>Ttc	p.L192F	SERPINE1_ENST00000445463.2_Missense_Mutation_p.L177F	NM_000602.4	NP_000593.1	P05121	PAI1_HUMAN	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	192					angiogenesis|cellular response to chemical stimulus|cellular response to lipopolysaccharide|chronological cell aging|defense response to Gram-negative bacterium|fibrinolysis|negative regulation of apoptosis|negative regulation of cell adhesion mediated by integrin|negative regulation of fibrinolysis|negative regulation of plasminogen activation|negative regulation of smooth muscle cell migration|negative regulation of smooth muscle cell-matrix adhesion|negative regulation of vascular wound healing|platelet activation|platelet degranulation|positive regulation of angiogenesis|positive regulation of interleukin-8 production|positive regulation of leukotriene production involved in inflammatory response|positive regulation of monocyte chemotaxis|positive regulation of receptor-mediated endocytosis|regulation of receptor activity	extracellular matrix|extracellular space|plasma membrane|platelet alpha granule lumen	protease binding|serine-type endopeptidase inhibitor activity			central_nervous_system(1)|endometrium(5)|kidney(2)|large_intestine(4)|lung(4)|ovary(1)|prostate(3)	20	Lung NSC(181;0.136)|all_lung(186;0.182)				Atorvastatin(DB01076)|Dimethyl sulfoxide(DB01093)|Drotrecogin alfa(DB00055)|Simvastatin(DB00641)|Tenecteplase(DB00031)|Troglitazone(DB00197)|Urokinase(DB00013)	GGTGAATGCCCTCTACTTCAA	0.557000													12	154					0	0	1	0	0
RASA3	22821	broad.mit.edu	37	13	114782770	114782770	+	Silent	SNP	G	G	A			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr13:114782770G>A	ENST00000334062.7	-	12	1270	c.1149C>T	c.(1147-1149)acC>acT	p.T383T	RASA3_ENST00000542651.1_3'UTR|RASA3_ENST00000389544.4_Silent_p.T351T	NM_007368.2	NP_031394.2	Q14644	RASA3_HUMAN	RAS p21 protein activator 3	383	Ras-GAP.				intracellular signal transduction|negative regulation of Ras protein signal transduction	cytoplasm|intrinsic to internal side of plasma membrane	calcium-release channel activity|metal ion binding|Ras GTPase activator activity			breast(1)|central_nervous_system(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(8)|lung(20)|ovary(3)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	47	Lung NSC(43;0.00814)|all_neural(89;0.0337)|Medulloblastoma(90;0.163)|Lung SC(71;0.218)	all_cancers(25;0.016)|all_epithelial(44;0.00577)|all_lung(25;0.0173)|Lung NSC(25;0.0634)|Breast(118;0.188)	BRCA - Breast invasive adenocarcinoma(86;0.128)			CCAGCTTCATGGTCTCGTCGA	0.627000											OREG0022538	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	10	154					0	0	1	0	0
ZNF438	220929	broad.mit.edu	37	10	31134165	31134165	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr10:31134165C>T	ENST00000452305.1	-	9	2745	c.2182G>A	c.(2182-2184)Gaa>Aaa	p.E728K	ZNF438_ENST00000361310.3_Missense_Mutation_p.E738K|ZNF438_ENST00000436087.2_Missense_Mutation_p.E738K|ZNF438_ENST00000413025.1_Missense_Mutation_p.E738K|ZNF438_ENST00000442986.1_Missense_Mutation_p.E738K|ZNF438_ENST00000375311.1_Missense_Mutation_p.E302K|ZNF438_ENST00000444692.2_Missense_Mutation_p.E728K|ZNF438_ENST00000331737.6_Missense_Mutation_p.E728K|ZNF438_ENST00000538351.2_Missense_Mutation_p.E689K	NM_001143770.1	NP_001137242.1	Q7Z4V0	ZN438_HUMAN	zinc finger protein 438	738					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(3)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(3)|lung(15)|ovary(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	35		Prostate(175;0.0587)				ATGAGCATTTCCACGCCATTC	0.537000													5	72					0	0	1	0	0
ADAMTS9	56999	broad.mit.edu	37	3	64580043	64580043	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr3:64580043C>T	ENST00000498707.1	-	28	4589	c.4247G>A	c.(4246-4248)cGg>cAg	p.R1416Q	ADAMTS9_ENST00000295903.4_Missense_Mutation_p.R1388Q	NM_182920.1	NP_891550.1	Q9P2N4	ATS9_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 9	1416	TSP type-1 10.				glycoprotein catabolic process|multicellular organismal development|proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			breast(3)|central_nervous_system(4)|cervix(1)|endometrium(9)|kidney(4)|large_intestine(17)|liver(4)|lung(43)|ovary(3)|prostate(3)|skin(2)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	100		Lung NSC(201;0.00682)		BRCA - Breast invasive adenocarcinoma(55;0.00142)|Kidney(15;0.00202)|KIRC - Kidney renal clear cell carcinoma(15;0.00221)		ATCTGGAAACCGTTCACCGTT	0.498000													8	144					0	0	1	0	0
ALG5	29880	broad.mit.edu	37	13	37524102	37524102	+	Missense_Mutation	SNP	C	C	G			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr13:37524102C>G	ENST00000239891.3	-	10	1018	c.952G>C	c.(952-954)Gag>Cag	p.E318Q	ALG5_ENST00000443765.1_Missense_Mutation_p.E288Q	NM_013338.4	NP_037470.1	Q9Y673	ALG5_HUMAN	ALG5, dolichyl-phosphate beta-glucosyltransferase	318					dolichol-linked oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	endoplasmic reticulum membrane|integral to membrane	dolichyl-phosphate beta-glucosyltransferase activity|oligosaccharyl transferase activity			breast(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(3)|stomach(1)|upper_aerodigestive_tract(1)	11		Breast(139;0.014)|Lung SC(185;0.0548)|Prostate(109;0.174)		all cancers(112;5.79e-07)|Epithelial(112;1.81e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.00785)|BRCA - Breast invasive adenocarcinoma(63;0.0127)|GBM - Glioblastoma multiforme(144;0.0472)		CGAGTTTGCTCAAGCCTCCAG	0.363000													3	27					0	0	1	0	0
ZDHHC7	55625	broad.mit.edu	37	16	85015570	85015570	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr16:85015570C>T	ENST00000313732.4	-	4	698	c.346G>A	c.(346-348)Gaa>Aaa	p.E116K	ZDHHC7_ENST00000564466.1_Missense_Mutation_p.E153K|ZDHHC7_ENST00000569488.1_Intron	NM_017740.2	NP_060210.2	Q9NXF8	ZDHC7_HUMAN	zinc finger, DHHC-type containing 7	116						integral to membrane	acyltransferase activity|protein binding|zinc ion binding			large_intestine(6)|lung(4)	10						TCCATGTATTCTTTCGTAGCG	0.512000													6	96					0	0	1	0	0
RTKN2	219790	broad.mit.edu	37	10	63957667	63957667	+	Silent	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr10:63957667C>T	ENST00000373789.3	-	12	1926	c.1830G>A	c.(1828-1830)taG>taA	p.*610*	RTKN2_ENST00000315289.2_Intron|RTKN2_ENST00000395265.1_Intron	NM_145307.2	NP_660350.2	Q8IZC4	RTKN2_HUMAN	rhotekin 2	0					signal transduction	intracellular				endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(3)|lung(6)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	21	Prostate(12;0.0297)|all_hematologic(501;0.215)					TAAGAGTTTTCTATACTTGTG	0.348000													3	13					0	0	1	0	0
FARP1	10160	broad.mit.edu	37	13	99092981	99092981	+	Missense_Mutation	SNP	C	C	T			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr13:99092981C>T	ENST00000376586.2	+	25	3116	c.2780C>T	c.(2779-2781)tCg>tTg	p.S927L	FARP1_ENST00000319562.6_Missense_Mutation_p.S896L|FARP1_ENST00000595437.1_Missense_Mutation_p.S927L			Q9Y4F1	FARP1_HUMAN	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)	896					regulation of Rho protein signal transduction	cytoplasm|cytoskeleton|extrinsic to membrane	cytoskeletal protein binding|Rho guanyl-nucleotide exchange factor activity	p.S896L(1)|p.S927L(1)		breast(3)|endometrium(6)|kidney(6)|large_intestine(13)|lung(16)|ovary(1)|skin(3)|urinary_tract(1)	49	all_neural(89;0.0982)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)		BRCA - Breast invasive adenocarcinoma(86;0.233)			CTGAGCGCCTCGCGCACATCG	0.627000													5	40					0	0	1	0	0
BEST4	266675	broad.mit.edu	37	1	45251285	45251285	+	Frame_Shift_Del	DEL	G	G	-			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr1:45251285delG	ENST00000372207.3	-	5	699	c.700delC	c.(700-702)ctcfs	p.L234fs		NM_153274.2	NP_695006.1	Q8NFU0	BEST4_HUMAN	bestrophin 4	234						chloride channel complex|plasma membrane	chloride channel activity			large_intestine(1)|lung(4)|ovary(1)|skin(1)	7	Acute lymphoblastic leukemia(166;0.155)					GTGTAGACGAGGGGGATGCTG	0.537											OREG0013447	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	4	---	---	---	---					
RRP36	88745	broad.mit.edu	37	6	42989414	42989419	+	In_Frame_Del	DEL	GCCGGG	GCCGGG	-	rs60664426		TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr6:42989414_42989419delGCCGGG	ENST00000244496.5	+	1	32_37	c.22_27delGCCGGG	c.(22-27)gccgggdel	p.AG14del		NM_033112.2	NP_149103.1	Q96EU6	RRP36_HUMAN	ribosomal RNA processing 36 homolog (S. cerevisiae)	14					ribosomal small subunit biogenesis|rRNA processing	nucleolus		p.A8_G9delAG(2)		NS(1)|breast(1)|central_nervous_system(1)|large_intestine(5)|lung(1)|ovary(1)|prostate(1)	11						TAACTAccgcgccggggccggggccg	0.777													3	6	---	---	---	---					
SPON1	10418	broad.mit.edu	37	11	14276276	14276277	+	RNA	DEL	GT	GT	-			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr11:14276276_14276277delGT	ENST00000310358.7	+	0	1627							Q9HCB6	SPON1_HUMAN	spondin 1, extracellular matrix protein						cell adhesion	extracellular space|proteinaceous extracellular matrix	protein binding			NS(1)|endometrium(1)|large_intestine(5)|lung(11)|prostate(2)|upper_aerodigestive_tract(1)	21				Epithelial(150;0.00898)		GACCTATGAGGTGTGTGTGTGT	0.594													7	42	---	---	---	---					
MMP12	4321	broad.mit.edu	37	11	102738793	102738794	+	RNA	INS	-	-	T	rs35342965	by1000genomes	TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr11:102738793_102738794insT	ENST00000532855.1	-	0	727_728							P39900	MMP12_HUMAN	matrix metallopeptidase 12 (macrophage elastase)						positive regulation of epithelial cell proliferation involved in wound healing|proteolysis|wound healing, spreading of epidermal cells	proteinaceous extracellular matrix	calcium ion binding|metalloendopeptidase activity|zinc ion binding			autonomic_ganglia(1)|cervix(1)|endometrium(1)|kidney(3)|large_intestine(4)|lung(9)|prostate(5)|skin(1)|upper_aerodigestive_tract(1)	26		all_hematologic(158;0.00092)|Acute lymphoblastic leukemia(157;0.000967)		BRCA - Breast invasive adenocarcinoma(274;0.014)	Acetohydroxamic Acid(DB00551)	TGAGGAACAAGTGGTGCCTAAG	0.416													3	6	---	---	---	---					
C16orf71	146562	broad.mit.edu	37	16	4796953	4796955	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-FD-A5BS-01A-21D-A26M-08	TCGA-FD-A5BS-10A-01D-A26K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fe7cd95d-937f-458f-9c64-f1649c4c1b15	91e3cd45-c230-41d6-ad89-9832229abd44	g.chr16:4796953_4796955delGAG	ENST00000299320.5	+	8	1685_1687	c.1207_1209delGAG	c.(1207-1209)gagdel	p.E409del	RP11-127I20.7_ENST00000588099.1_RNA|C16orf71_ENST00000590191.1_In_Frame_Del_p.E426del	NM_139170.2	NP_631909.2	Q8IYS4	CP071_HUMAN	chromosome 16 open reading frame 71	409								p.E403delE(1)		breast(1)|central_nervous_system(1)|large_intestine(4)|lung(4)|ovary(1)	11						CTCTGACAGTGAGGAGGAGGAGG	0.611													3	6	---	---	---	---					
