Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
ADAMTS6	0	genome.wustl.edu	37	5	64747324	64747324	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	5	64747324	64747324	C	T	SNP	ADAMTS6	ENST00000381055	human	ensembl	69_37n	-1	known	missense	c.1051	p.D351N	1.000	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B	-	no_errors	ADAMTS6	HGNC	ENSG00000049192	522	0	0.00	385	76	16.41	-	-	-
ADAMTS6	0	genome.wustl.edu	37	5	64747324	64747324	+	Missense_Mutation	SNP	C	C	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	5	64747324	64747324	C	T	SNP	ADAMTS6	ENST00000381055	human	ensembl	69_37n	-1	known	missense	c.1051	p.D351N	1.000	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_ADAM_spacer1,pfam_Peptidase_M12B_N,pfam_Peptidase_M12B,pfam_Thrombospondin_1_rpt,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B	-	no_errors	ADAMTS6	HGNC	ENSG00000049192	529	0	0.00	385	76	16.41	-	-	-
ADAMTSL5	0	genome.wustl.edu	37	19	1507614	1507614	+	Silent	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	19	1507614	1507614	G	A	SNP	ADAMTSL5	ENST00000413997	human	ensembl	69_37n	-1	known	silent	c.660	p.T220	1.000	pfam_ADAM_spacer1	pfam_ADAM_spacer1,pfam_Netrin_module_non-TIMP,pfam_Thrombospondin_1_rpt,superfamily_TIMP-like_OB-fold,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_Netrin_module_non-TIMP,pfscan_Netrin_domain,pfscan_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTSL5	HGNC	ENSG00000185761	53	0	0.00	47	9	15.79	-	-	-
ADAMTSL5	0	genome.wustl.edu	37	19	1507614	1507614	+	Silent	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	19	1507614	1507614	G	A	SNP	ADAMTSL5	ENST00000413997	human	ensembl	69_37n	-1	known	silent	c.660	p.T220	1.000	pfam_ADAM_spacer1	pfam_ADAM_spacer1,pfam_Netrin_module_non-TIMP,pfam_Thrombospondin_1_rpt,superfamily_TIMP-like_OB-fold,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,smart_Netrin_module_non-TIMP,pfscan_Netrin_domain,pfscan_Thrombospondin_1_rpt,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTSL5	HGNC	ENSG00000185761	50	0	0.00	47	9	15.79	-	-	-
CD86	0	genome.wustl.edu	37	3	121825056	121825056	+	Nonsense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	3	121825056	121825056	C	G	SNP	CD86	ENST00000478741	human	ensembl	69_37n	+1	novel	nonsense	c.398	p.S133*	1.000	NULL	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	CD86	HGNC	ENSG00000114013	114	0	0.00	84	19	18.45	-	-	-
CD86	0	genome.wustl.edu	37	3	121825056	121825056	+	Nonsense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	3	121825056	121825056	C	G	SNP	CD86	ENST00000478741	human	ensembl	69_37n	+1	novel	nonsense	c.398	p.S133*	1.000	NULL	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	CD86	HGNC	ENSG00000114013	129	0	0.00	84	19	18.45	-	-	-
CPNE5	0	genome.wustl.edu	37	6	36713227	36713227	+	Silent	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	6	36713227	36713227	G	A	SNP	CPNE5	ENST00000244751	human	ensembl	69_37n	-1	known	silent	c.1266	p.S422	1.000	pfam_Copine,smart_VWF_A,pfscan_VWF_A	pfam_Copine,pfam_C2_Ca-dep,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_C2_Ca-dep,smart_VWF_A,pfscan_C2_membr_targeting,pfscan_VWF_A	-	no_errors	CPNE5	HGNC	ENSG00000124772	24	0	0.00	32	7	17.50	-	-	-
CPNE5	0	genome.wustl.edu	37	6	36713227	36713227	+	Silent	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	6	36713227	36713227	G	A	SNP	CPNE5	ENST00000244751	human	ensembl	69_37n	-1	known	silent	c.1266	p.S422	1.000	pfam_Copine,smart_VWF_A,pfscan_VWF_A	pfam_Copine,pfam_C2_Ca-dep,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_C2_Ca-dep,smart_VWF_A,pfscan_C2_membr_targeting,pfscan_VWF_A	-	no_errors	CPNE5	HGNC	ENSG00000124772	26	0	0.00	32	7	17.50	-	-	-
EFHA2	0	genome.wustl.edu	37	8	16944529	16944529	+	Missense_Mutation	SNP	A	A	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	8	16944529	16944529	A	G	SNP	EFHA2	ENST00000519044	human	ensembl	69_37n	+1	novel	missense	c.407	p.K136R	1.000	NULL	smart_EF_hand_Ca-bd,pfscan_EF_HAND_2	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	EFHA2	HGNC	ENSG00000155970	529	0	0.00	375	65	14.77	-	-	-
EFHA2	0	genome.wustl.edu	37	8	16944529	16944529	+	Missense_Mutation	SNP	A	A	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	8	16944529	16944529	A	G	SNP	EFHA2	ENST00000519044	human	ensembl	69_37n	+1	novel	missense	c.407	p.K136R	1.000	NULL	smart_EF_hand_Ca-bd,pfscan_EF_HAND_2	-	no_start_codon:pseudogene:no_stop_codon:bad_bp_length_for_coding_region	EFHA2	HGNC	ENSG00000155970	473	0	0.00	375	65	14.77	-	-	-
FAM171A1	0	genome.wustl.edu	37	10	15290661	15290661	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	10	15290661	15290661	G	A	SNP	FAM171A1	ENST00000378116	human	ensembl	69_37n	-1	known	missense	c.731	p.A244V	0.966	pfam_Uncharacterised_FAM171	pfam_Uncharacterised_FAM171	-	no_errors	FAM171A1	HGNC	ENSG00000148468	47	0	0.00	51	13	20.31	-	-	-
FAM171A1	0	genome.wustl.edu	37	10	15290661	15290661	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	10	15290661	15290661	G	A	SNP	FAM171A1	ENST00000378116	human	ensembl	69_37n	-1	known	missense	c.731	p.A244V	0.966	pfam_Uncharacterised_FAM171	pfam_Uncharacterised_FAM171	-	no_errors	FAM171A1	HGNC	ENSG00000148468	49	0	0.00	51	13	20.31	-	-	-
FAM182A	0	genome.wustl.edu	37	20	26063548	26063548	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	20	26063548	26063548	G	A	SNP	FAM182A	ENST00000246000	human	ensembl	69_37n	+1	known	missense	c.397	p.E133K	0.051	NULL	NULL	-	no_errors	FAM182A	HGNC	ENSG00000125804	335	0	0.00	277	43	13.44	-	-	-
FAM182A	0	genome.wustl.edu	37	20	26063548	26063548	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	20	26063548	26063548	G	A	SNP	FAM182A	ENST00000246000	human	ensembl	69_37n	+1	known	missense	c.397	p.E133K	0.051	NULL	NULL	-	no_errors	FAM182A	HGNC	ENSG00000125804	316	0	0.00	277	43	13.44	-	-	-
GTF2F2	0	genome.wustl.edu	37	13	45694797	45694797	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	13	45694797	45694797	G	A	SNP	GTF2F2	ENST00000340473	human	ensembl	69_37n	+1	known	missense	c.7	p.E3K	1.000	superfamily_TFIIF_interaction,pirsf_TFIIF-beta_subgr	pfam_TFIIF_beta,superfamily_TFIIF_interaction,pirsf_TFIIF-beta_subgr	-	no_errors	GTF2F2	HGNC	ENSG00000188342	30	0	0.00	22	4	15.38	-	-	-
GTF2F2	0	genome.wustl.edu	37	13	45694797	45694797	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	13	45694797	45694797	G	A	SNP	GTF2F2	ENST00000340473	human	ensembl	69_37n	+1	known	missense	c.7	p.E3K	1.000	superfamily_TFIIF_interaction,pirsf_TFIIF-beta_subgr	pfam_TFIIF_beta,superfamily_TFIIF_interaction,pirsf_TFIIF-beta_subgr	-	no_errors	GTF2F2	HGNC	ENSG00000188342	32	0	0.00	22	4	15.38	-	-	-
HCFC2	0	genome.wustl.edu	37	12	104461732	104461732	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	12	104461732	104461732	G	A	SNP	HCFC2	ENST00000229330	human	ensembl	69_37n	+1	known	missense	c.320	p.R107H	1.000	NULL	pfam_Kelch_1,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	HCFC2	HGNC	ENSG00000111727	420	0	0.00	306	53	14.64	-	-	-
HCFC2	0	genome.wustl.edu	37	12	104461732	104461732	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	12	104461732	104461732	G	A	SNP	HCFC2	ENST00000229330	human	ensembl	69_37n	+1	known	missense	c.320	p.R107H	1.000	NULL	pfam_Kelch_1,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	HCFC2	HGNC	ENSG00000111727	367	0	0.00	306	53	14.64	-	-	-
HTT	0	genome.wustl.edu	37	4	3148607	3148607	+	Nonsense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	4	3148607	3148607	C	G	SNP	HTT	ENST00000355072	human	ensembl	69_37n	+1	known	nonsense	c.3227	p.S1076*	0.998	superfamily_ARM-type_fold	pfam_Huntingtin_middle-repeat,pfam_HEAT,superfamily_ARM-type_fold,prints_Huntingtin	-	no_errors	HTT	HGNC	ENSG00000197386	312	0	0.00	273	61	18.26	-	-	-
HTT	0	genome.wustl.edu	37	4	3148607	3148607	+	Nonsense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	4	3148607	3148607	C	G	SNP	HTT	ENST00000355072	human	ensembl	69_37n	+1	known	nonsense	c.3227	p.S1076*	0.998	superfamily_ARM-type_fold	pfam_Huntingtin_middle-repeat,pfam_HEAT,superfamily_ARM-type_fold,prints_Huntingtin	-	no_errors	HTT	HGNC	ENSG00000197386	332	0	0.00	273	61	18.26	-	-	-
LIFR	0	genome.wustl.edu	37	5	38506735	38506735	+	Splice_Site	DEL	C	C	-			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	5	38506735	38506735	C	-	DEL	LIFR	ENST00000263409	human	ensembl	69_37n	-1	known	splice_site_del	c.992-1	e7-1	1.000	-	-	-	no_errors	LIFR	HGNC	ENSG00000113594	150	0	0.00	111	19	14.39	-	-	-
LIFR	0	genome.wustl.edu	37	5	38506735	38506735	+	Splice_Site	DEL	C	C	-			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	5	38506735	38506735	C	-	DEL	LIFR	ENST00000263409	human	ensembl	69_37n	-1	known	splice_site_del	c.992-1	e7-1	1.000	-	-	-	no_errors	LIFR	HGNC	ENSG00000113594	149	0	0.00	111	19	14.39	-	-	-
LRRIQ1	0	genome.wustl.edu	37	12	85460647	85460647	+	Missense_Mutation	SNP	A	A	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	12	85460647	85460647	A	C	SNP	LRRIQ1	ENST00000393217	human	ensembl	69_37n	+1	known	missense	c.2666	p.E889A	1.000	NULL	pfam_IQ_motif_EF-hand-BS,smart_IQ_motif_EF-hand-BS,smart_Leu-rich_rpt_typical-subtyp,pfscan_IQ_motif_EF-hand-BS	-	no_errors	LRRIQ1	HGNC	ENSG00000133640	254	1	0.39	178	45	20.18	-	-	-
LRRIQ1	0	genome.wustl.edu	37	12	85460647	85460647	+	Missense_Mutation	SNP	A	A	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	12	85460647	85460647	A	C	SNP	LRRIQ1	ENST00000393217	human	ensembl	69_37n	+1	known	missense	c.2666	p.E889A	1.000	NULL	pfam_IQ_motif_EF-hand-BS,smart_IQ_motif_EF-hand-BS,smart_Leu-rich_rpt_typical-subtyp,pfscan_IQ_motif_EF-hand-BS	-	no_errors	LRRIQ1	HGNC	ENSG00000133640	197	1	0.51	178	45	20.18	-	-	-
LTBP1	0	genome.wustl.edu	37	2	33540311	33540311	+	Missense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	2	33540311	33540311	C	G	SNP	LTBP1	ENST00000354476	human	ensembl	69_37n	+1	known	missense	c.3708	p.I1236M	0.964	pfam_EGF-like_Ca-bd,smart_EGF-like_Ca-bd,smart_EGF-like,pfscan_EG-like_dom	pfam_EGF-like_Ca-bd,pfam_TB_dom,pfam_EGF-like_dom,superfamily_TB_dom,smart_EGF-like,smart_EGF-like_Ca-bd,pfscan_EG-like_dom	-	no_errors	LTBP1	HGNC	ENSG00000049323	226	0	0.00	168	33	16.34	-	-	-
LTBP1	0	genome.wustl.edu	37	2	33540311	33540311	+	Missense_Mutation	SNP	C	C	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	2	33540311	33540311	C	G	SNP	LTBP1	ENST00000354476	human	ensembl	69_37n	+1	known	missense	c.3708	p.I1236M	0.964	pfam_EGF-like_Ca-bd,smart_EGF-like_Ca-bd,smart_EGF-like,pfscan_EG-like_dom	pfam_EGF-like_Ca-bd,pfam_TB_dom,pfam_EGF-like_dom,superfamily_TB_dom,smart_EGF-like,smart_EGF-like_Ca-bd,pfscan_EG-like_dom	-	no_errors	LTBP1	HGNC	ENSG00000049323	224	0	0.00	168	33	16.34	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56183240	56183241	+	Frame_Shift_Ins	INS	-	-	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	5	56183240	56183241	-	T	INS	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.4150_4151	p.R1385fs	1.000:1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	417	0	0.00	305	46	13.11	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56183240	56183241	+	Frame_Shift_Ins	INS	-	-	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	5	56183240	56183241	-	T	INS	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.4150_4151	p.R1385fs	1.000:1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	402	0	0.00	305	46	13.11	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56183296	56183297	+	Frame_Shift_Ins	INS	-	-	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	5	56183296	56183297	-	G	INS	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.4206_4207	p.E1403fs	0.930:1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	498	0	0.00	389	60	13.36	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56183296	56183297	+	Frame_Shift_Ins	INS	-	-	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	5	56183296	56183297	-	G	INS	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_ins	c.4206_4207	p.E1403fs	0.930:1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	471	0	0.00	389	60	13.36	-	-	-
MST1P9	0	genome.wustl.edu	37	1	17085995	17085996	+	Frame_Shift_Ins	INS	-	-	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	1	17085995	17085996	-	C	INS	MST1P9	ENST00000334998	human	ensembl	69_37n	-1	known	frame_shift_ins	c.902_901	p.A301fs	0.980:0.979	pfam_Kringle,superfamily_Kringle-like,smart_Kringle,pfscan_Kringle	pfam_Kringle,pfam_Peptidase_S1_S6,pfam_PAN-1_domain,superfamily_Pept_cys/ser_Trypsin-like,superfamily_Kringle-like,smart_Pan_app,smart_Kringle,smart_Peptidase_S1_S6,pfscan_Pan_app,pfscan_Kringle,pfscan_Peptidase_S1_S6	-	no_errors	MST1P9	HGNC	ENSG00000186715	27	0	0.00	24	3	11.11	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178952085	178952085	+	Missense_Mutation	SNP	A	A	G			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	3	178952085	178952085	A	G	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.3140	p.H1047R	1.000	superfamily_Kinase-like_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	229	0	0.00	204	28	12.07	-	-	-
PPP3CA	0	genome.wustl.edu	37	4	101950343	101950343	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	4	101950343	101950343	T	C	SNP	PPP3CA	ENST00000394854	human	ensembl	69_37n	-1	known	missense	c.1349	p.E450G	1.000	NULL	pfam_Metallo_PEstase_dom,smart_Ser/Thr-sp_prot-phosphatase,prints_Ser/Thr-sp_prot-phosphatase	-	no_errors	PPP3CA	HGNC	ENSG00000138814	154	0	0.00	126	17	11.89	-	-	-
PPP3CA	0	genome.wustl.edu	37	4	101950343	101950343	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	4	101950343	101950343	T	C	SNP	PPP3CA	ENST00000394854	human	ensembl	69_37n	-1	known	missense	c.1349	p.E450G	1.000	NULL	pfam_Metallo_PEstase_dom,smart_Ser/Thr-sp_prot-phosphatase,prints_Ser/Thr-sp_prot-phosphatase	-	no_errors	PPP3CA	HGNC	ENSG00000138814	180	0	0.00	126	17	11.89	-	-	-
RFX2	0	genome.wustl.edu	37	19	6001886	6001886	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	19	6001886	6001886	G	T	SNP	RFX2	ENST00000303657	human	ensembl	69_37n	-1	known	missense	c.1799	p.A600D	0.573	NULL	pfam_RFX1_trans_act,pfam_DNA-bd_RFX	-	no_errors	RFX2	HGNC	ENSG00000087903	42	0	0.00	28	5	15.15	-	-	-
RFX2	0	genome.wustl.edu	37	19	6001886	6001886	+	Missense_Mutation	SNP	G	G	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	19	6001886	6001886	G	T	SNP	RFX2	ENST00000303657	human	ensembl	69_37n	-1	known	missense	c.1799	p.A600D	0.573	NULL	pfam_RFX1_trans_act,pfam_DNA-bd_RFX	-	no_errors	RFX2	HGNC	ENSG00000087903	30	0	0.00	28	5	15.15	-	-	-
SPINK5	0	genome.wustl.edu	37	5	147484520	147484520	+	Missense_Mutation	SNP	A	A	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	5	147484520	147484520	A	T	SNP	SPINK5	ENST00000359874	human	ensembl	69_37n	+1	known	missense	c.1436	p.Q479L	0.801	pfam_Kazal-type_dom,smart_Prot_inh_Kazal	pfam_Kazal-type_dom,pfam_Prot_inh_Kazal,smart_Prot_inh_Kazal	-	no_errors	SPINK5	HGNC	ENSG00000133710	362	0	0.00	289	53	15.50	-	-	-
SPINK5	0	genome.wustl.edu	37	5	147484520	147484520	+	Missense_Mutation	SNP	A	A	T			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	5	147484520	147484520	A	T	SNP	SPINK5	ENST00000359874	human	ensembl	69_37n	+1	known	missense	c.1436	p.Q479L	0.801	pfam_Kazal-type_dom,smart_Prot_inh_Kazal	pfam_Kazal-type_dom,pfam_Prot_inh_Kazal,smart_Prot_inh_Kazal	-	no_errors	SPINK5	HGNC	ENSG00000133710	303	0	0.00	289	53	15.50	-	-	-
TMCC1	0	genome.wustl.edu	37	3	129370451	129370451	+	Missense_Mutation	SNP	A	A	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	3	129370451	129370451	A	C	SNP	TMCC1	ENST00000393238	human	ensembl	69_37n	-1	known	missense	c.1835	p.V612G	0.995	pfam_Predicted_TM_coiled-coil_2	pfam_Predicted_TM_coiled-coil_2	-	no_errors	TMCC1	HGNC	ENSG00000172765	217	1	0.46	141	25	15.06	-	-	-
TTC17	0	genome.wustl.edu	37	11	43428954	43428954	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	11	43428954	43428954	G	A	SNP	TTC17	ENST00000039989	human	ensembl	69_37n	+1	known	missense	c.1891	p.A631T	1.000	smart_TPR_repeat,pfscan_TPR-contain_dom	pfam_TPR-1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TTC17	HGNC	ENSG00000052841	324	0	0.00	249	40	13.84	-	-	-
ZCCHC12	0	genome.wustl.edu	37	X	117960412	117960412	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	X	117960412	117960412	T	C	SNP	ZCCHC12	ENST00000310164	human	ensembl	69_37n	+1	known	missense	c.1205	p.L402P	0.000	NULL	superfamily_Znf_CCHC	-	no_errors	ZCCHC12	HGNC	ENSG00000174460	58	0	0.00	53	8	13.11	-	-	-
ZCCHC12	0	genome.wustl.edu	37	X	117960412	117960412	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	X	117960412	117960412	T	C	SNP	ZCCHC12	ENST00000310164	human	ensembl	69_37n	+1	known	missense	c.1205	p.L402P	0.000	NULL	superfamily_Znf_CCHC	-	no_errors	ZCCHC12	HGNC	ENSG00000174460	65	0	0.00	53	8	13.11	-	-	-
ZNF619	0	genome.wustl.edu	37	3	40529529	40529529	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	42ae8faa-3a1c-4068-a71e-612c411bf102	3	40529529	40529529	T	C	SNP	ZNF619	ENST00000447116	human	ensembl	69_37n	+1	known	missense	c.1648	p.C550R	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF619	HGNC	ENSG00000177873	411	0	0.00	316	48	13.01	-	-	-
ZNF619	0	genome.wustl.edu	37	3	40529529	40529529	+	Missense_Mutation	SNP	T	T	C			TCGA-BH-A0BO-01A-23D-A12B-09	TCGA-BH-A0BO-11A-11D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	63af8579-99b1-4f81-92a6-4e3a31715be1	2f936210-a942-4f9b-8456-04c8e8cfb09f	3	40529529	40529529	T	C	SNP	ZNF619	ENST00000447116	human	ensembl	69_37n	+1	known	missense	c.1648	p.C550R	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF619	HGNC	ENSG00000177873	392	1	0.25	316	48	13.01	-	-	-
