Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
ADAM19	0	genome.wustl.edu	37	5	156945842	156945842	+	Missense_Mutation	SNP	C	C	G			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	5	156945842	156945842	C	G	SNP	ADAM19	ENST00000394020	human	ensembl	69_37n	-1	known	missense	c.661	p.D221H	1.000	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_Cys-rich,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_EG-like_dom,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM19	HGNC	ENSG00000135074	325	0	0.00	215	132	38.04	-	-	-
CEP78	0	genome.wustl.edu	37	9	80856675	80856675	+	Missense_Mutation	SNP	T	T	C			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	9	80856675	80856675	T	C	SNP	CEP78	ENST00000376597	human	ensembl	69_37n	+1	known	missense	c.563	p.L188P	1.000	NULL	smart_Leu-rich_rpt_RNase_inh_sub-typ	-	no_errors	CEP78	HGNC	ENSG00000148019	247	0	0.00	268	60	18.24	-	-	-
CTCF	0	genome.wustl.edu	37	16	67644796	67644796	+	Nonsense_Mutation	SNP	G	G	T			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	16	67644796	67644796	G	T	SNP	CTCF	ENST00000264010	human	ensembl	69_37n	+1	known	nonsense	c.61	p.E21*	1.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	CTCF	HGNC	ENSG00000102974	74	0	0.00	5	31	86.11	-	-	-
DAK	0	genome.wustl.edu	37	11	61105416	61105416	+	Missense_Mutation	SNP	T	T	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	11	61105416	61105416	T	A	SNP	DAK	ENST00000394900	human	ensembl	69_37n	+1	known	missense	c.7	p.S3T	0.974	NULL	pfam_Dak1,pfam_Dak2,superfamily_Dak2,tigrfam_DhaK_ATP	-	no_errors	DAK	HGNC	ENSG00000149476	105	0	0.00	81	51	38.64	-	-	-
DSP	0	genome.wustl.edu	37	6	7583485	7583485	+	Missense_Mutation	SNP	G	G	T			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	6	7583485	7583485	G	T	SNP	DSP	ENST00000379802	human	ensembl	69_37n	+1	known	missense	c.5990	p.G1997V	1.000	NULL	pfam_Plectin_repeat,smart_Spectrin/alpha-actinin,smart_Plectin_repeat	-	no_errors	DSP	HGNC	ENSG00000096696	216	0	0.00	143	92	39.15	-	-	-
DSPP	0	genome.wustl.edu	37	4	88537151	88537151	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	4	88537151	88537151	G	A	SNP	DSPP	ENST00000282478	human	ensembl	69_37n	+1	known	missense	c.3337	p.D1113N	0.494	NULL	NULL	-	no_errors	DSPP	HGNC	ENSG00000152591	55	0	0.00	44	6	12.00	-	-	-
FMN1	0	genome.wustl.edu	37	15	33256405	33256405	+	Frame_Shift_Del	DEL	T	T	-			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	15	33256405	33256405	T	-	DEL	FMN1	ENST00000334528	human	ensembl	69_37n	-1	known	frame_shift_del	c.2372	p.D791fs	1.000	pfam_FH2_actin-bd,superfamily_FH2_actin-bd,smart_Actin-bd_FH2/DRF_autoreg,prints_Formin	pfam_FH2_actin-bd,superfamily_FH2_actin-bd,smart_Actin-bd_FH2/DRF_autoreg,prints_Formin	-	no_errors	FMN1	HGNC	ENSG00000248905	562	0	0.00	277	186	38.11	-	-	-
HDLBP	0	genome.wustl.edu	37	2	242202328	242202328	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	2	242202328	242202328	G	A	SNP	HDLBP	ENST00000310931	human	ensembl	69_37n	-1	known	missense	c.248	p.P83L	1.000	NULL	pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1	-	no_errors	HDLBP	HGNC	ENSG00000115677	410	0	0.00	304	222	42.05	-	-	-
HSF1	0	genome.wustl.edu	37	8	145535048	145535048	+	Missense_Mutation	SNP	C	C	G			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	8	145535048	145535048	C	G	SNP	HSF1	ENST00000528838	human	ensembl	69_37n	+1	known	missense	c.606	p.I202M	1.000	NULL	pfam_Vert_HS_TF,pfam_HSF_DNA-bd,smart_HSF_DNA-bd,prints_HSF_DNA-bd	-	no_errors	HSF1	HGNC	ENSG00000185122	92	0	0.00	49	37	43.02	-	-	-
MAP3K1	0	genome.wustl.edu	37	5	56168483	56168483	+	Frame_Shift_Del	DEL	G	G	-			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	5	56168483	56168483	G	-	DEL	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_del	c.1439	p.R480fs	1.000	pfscan_Znf_RING	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	264	0	0.00	95	58	36.48	-	-	-
PEAK1	0	genome.wustl.edu	37	15	77406833	77406833	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	15	77406833	77406833	G	A	SNP	PEAK1	ENST00000312493	human	ensembl	69_37n	-1	known	missense	c.4906	p.R1636W	0.882	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	PEAK1	Clone_based_vega_gene	ENSG00000173517	248	0	0.00	347	52	13.03	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178936082	178936082	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	3	178936082	178936082	G	A	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.1624	p.E542K	1.000	pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	265	0	0.00	25	240	90.23	-	-	-
TCEB3	0	genome.wustl.edu	37	1	24078169	24078170	+	Frame_Shift_Ins	INS	-	-	C			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	1	24078169	24078170	-	C	INS	TCEB3	ENST00000418390	human	ensembl	69_37n	+1	known	frame_shift_ins	c.1152_1153	p.K385fs	0.000:0.464	NULL	pfam_RNA_pol_II_trans_fac_SIII_A,pfam_TFIIS_N,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,pfscan_F-box_dom_cyclin-like	-	no_errors	TCEB3	HGNC	ENSG00000011007	142	0	0.00	105	61	36.75	-	-	-
TRBV5-4	0	genome.wustl.edu	37	7	142168485	142168485	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	7	142168485	142168485	G	A	SNP	TRBV5-4	ENST00000454561	human	ensembl	69_37n	-1	known	missense	c.238	p.P80S	0.000	pfam_Ig_V-set,smart_Ig_V-set_subgr,pfscan_Ig-like	pfam_Ig_V-set,smart_Ig_V-set_subgr,pfscan_Ig-like	-	no_stop_codon:bad_bp_length_for_coding_region	TRBV5-4	HGNC	ENSG00000230099	183	0	0.00	109	75	40.76	-	-	-
TRIM71	0	genome.wustl.edu	37	3	32933232	32933232	+	Missense_Mutation	SNP	G	G	A			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	3	32933232	32933232	G	A	SNP	TRIM71	ENST00000383763	human	ensembl	69_37n	+1	known	missense	c.2536	p.G846S	1.000	pfam_NHL_repeat,pfscan_NHL_repeat_subgr	pfam_NHL_repeat,pfam_Filamin/ABP280_repeat-like,pfam_Znf_B-box,superfamily_Ig_E-set,smart_Znf_RING,smart_Znf_B-box,smart_Filamin,pfscan_Filamin/ABP280_repeat-like,pfscan_NHL_repeat_subgr,pfscan_Znf_B-box,pfscan_Znf_RING	-	no_errors	TRIM71	HGNC	ENSG00000206557	44	0	0.00	48	28	35.90	-	-	-
TTN	0	genome.wustl.edu	37	2	179514309	179514310	+	Frame_Shift_Ins	INS	-	-	TG			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	2	179514309	179514310	-	TG	INS	TTN	ENST00000589042	human	ensembl	69_37n	-1	putative	frame_shift_ins	c.39945_39944	p.K13316fs	0.948:0.886	superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_PPAK_motif,pfam_Titin_Z,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,superfamily_ARM-type_fold,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like	-	no_errors	TTN	HGNC	ENSG00000155657	14	0	0.00	1	2	66.67	-	-	-
ZNF215	0	genome.wustl.edu	37	11	6964815	6964815	+	Nonsense_Mutation	SNP	G	G	T			TCGA-E2-A156-01A-11D-A12B-09	TCGA-E2-A156-10A-01D-A12B-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	26003dce-0fc6-4538-a392-c80e1ebaa1e4	dd7e44af-58e2-43a5-af9c-29a48df02235	11	6964815	6964815	G	T	SNP	ZNF215	ENST00000278319	human	ensembl	69_37n	+1	known	nonsense	c.655	p.E219*	0.009	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZNF215	HGNC	ENSG00000149054	404	0	0.00	225	112	33.23	-	-	-
