#version 2.4
## 
## Oncotator v1.8.0.0 | Flat File Reference hg19 | GENCODE v19 EFFECT | UniProt_AAxform 2014_12 | ClinVar 12.03.20 | ESP 6500SI-V2 | ORegAnno UCSC Track | dbSNP build 142 | CCLE_By_GP 09292010 | COSMIC v62_291112 | 1000gp3 20130502 | UniProt_AA 2014_12 | dbNSFP v2.4 | ESP 6500SI-V2 | COSMIC_FusionGenes v62_291112 | gencode_xref_refseq metadata_v19 | CCLE_By_Gene 09292010 | ACHILLES_Lineage_Results 110303 | CGC full_2012-03-15 | UniProt 2014_12 | HumanDNARepairGenes 20110905 | HGNC Sept172014 | COSMIC_Tissue 291112 | Familial_Cancer_Genes 20110905 | TUMORScape 20100104 | Ensembl ICGC MUCOPA | TCGAScape 110405 | MutSig Published Results 20110905 
Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	i_1000gp3_AA	i_1000gp3_AC	i_1000gp3_AF	i_1000gp3_AFR_AF	i_1000gp3_AMR_AF	i_1000gp3_AN	i_1000gp3_CIEND	i_1000gp3_CIPOS	i_1000gp3_CS	i_1000gp3_DP	i_1000gp3_EAS_AF	i_1000gp3_END	i_1000gp3_EUR_AF	i_1000gp3_IMPRECISE	i_1000gp3_MC	i_1000gp3_MEINFO	i_1000gp3_MEND	i_1000gp3_MLEN	i_1000gp3_MSTART	i_1000gp3_NS	i_1000gp3_SAS_AF	i_1000gp3_SVLEN	i_1000gp3_SVTYPE	i_1000gp3_TSD	i_ACHILLES_Lineage_Results_Top_Genes	i_BAM_File	i_CGC_Cancer Germline Mut	i_CGC_Cancer Molecular Genetics	i_CGC_Cancer Somatic Mut	i_CGC_Cancer Syndrome	i_CGC_Chr	i_CGC_Chr Band	i_CGC_GeneID	i_CGC_Name	i_CGC_Other Germline Mut	i_CGC_Tissue Type	i_COSMIC_n_overlapping_mutations	i_COSMIC_overlapping_mutation_descriptions	i_COSMIC_overlapping_primary_sites	i_ClinVar_ASSEMBLY	i_ClinVar_HGMD_ID	i_ClinVar_SYM	i_ClinVar_TYPE	i_ClinVar_rs	i_ESP_AA	i_ESP_AAC	i_ESP_AA_AC	i_ESP_AA_AGE	i_ESP_AA_GTC	i_ESP_AvgAAsampleReadDepth	i_ESP_AvgEAsampleReadDepth	i_ESP_AvgSampleReadDepth	i_ESP_CA	i_ESP_CDP	i_ESP_CG	i_ESP_CP	i_ESP_Chromosome	i_ESP_DBSNP	i_ESP_DP	i_ESP_EA_AC	i_ESP_EA_AGE	i_ESP_EA_GTC	i_ESP_EXOME_CHIP	i_ESP_FG	i_ESP_GL	i_ESP_GM	i_ESP_GS	i_ESP_GTC	i_ESP_GTS	i_ESP_GWAS_PUBMED	i_ESP_MAF	i_ESP_PH	i_ESP_PP	i_ESP_Position	i_ESP_TAC	i_ESP_TotalAAsamplesCovered	i_ESP_TotalEAsamplesCovered	i_ESP_TotalSamplesCovered	i_EVS_AA	i_EVS_All	i_EVS_EA	i_Ensembl_so_accession	i_Ensembl_so_term	i_Entrez_Gene_Id	i_Familial_Cancer_Genes_Reference	i_Familial_Cancer_Genes_Synonym	i_HGNC_Accession Numbers	i_HGNC_CCDS IDs	i_HGNC_Chromosome	i_HGNC_Date Modified	i_HGNC_Date Name Changed	i_HGNC_Date Symbol Changed	i_HGNC_Ensembl Gene ID	i_HGNC_Ensembl ID(supplied by Ensembl)	i_HGNC_Enzyme IDs	i_HGNC_Gene family description	i_HGNC_HGNC ID	i_HGNC_Locus Group	i_HGNC_Locus Type	i_HGNC_Name Synonyms	i_HGNC_OMIM ID(supplied by NCBI)	i_HGNC_Previous Names	i_HGNC_Previous Symbols	i_HGNC_Primary IDs	i_HGNC_Pubmed IDs	i_HGNC_Record Type	i_HGNC_RefSeq(supplied by NCBI)	i_HGNC_Secondary IDs	i_HGNC_Status	i_HGNC_Synonyms	i_HGNC_UCSC ID(supplied by UCSC)	i_HGNC_UniProt ID(supplied by UniProt)	i_HGNC_VEGA IDs	i_HGVS_coding_DNA_change	i_HGVS_genomic_change	i_HGVS_protein_change	i_ORegAnno_bin	i_UniProt_alt_uniprot_accessions	i_Variant_Classification	i_Variant_Type	i_all_domains_WU	i_amino_acid_change_WU	i_annotation_transcript	i_build	i_c_position_WU	i_ccds_id	i_chromosome_name_WU	i_dbNSFP_1000Gp1_AC	i_dbNSFP_1000Gp1_AF	i_dbNSFP_1000Gp1_AFR_AC	i_dbNSFP_1000Gp1_AFR_AF	i_dbNSFP_1000Gp1_AMR_AC	i_dbNSFP_1000Gp1_AMR_AF	i_dbNSFP_1000Gp1_ASN_AC	i_dbNSFP_1000Gp1_ASN_AF	i_dbNSFP_1000Gp1_EUR_AC	i_dbNSFP_1000Gp1_EUR_AF	i_dbNSFP_Ancestral_allele	i_dbNSFP_CADD_phred	i_dbNSFP_CADD_raw	i_dbNSFP_CADD_raw_rankscore	i_dbNSFP_ESP6500_AA_AF	i_dbNSFP_ESP6500_EA_AF	i_dbNSFP_Ensembl_geneid	i_dbNSFP_Ensembl_transcriptid	i_dbNSFP_FATHMM_pred	i_dbNSFP_FATHMM_rankscore	i_dbNSFP_FATHMM_score	i_dbNSFP_GERP++_NR	i_dbNSFP_GERP++_RS	i_dbNSFP_GERP++_RS_rankscore	i_dbNSFP_Interpro_domain	i_dbNSFP_LRT_Omega	i_dbNSFP_LRT_converted_rankscore	i_dbNSFP_LRT_pred	i_dbNSFP_LRT_score	i_dbNSFP_LR_pred	i_dbNSFP_LR_rankscore	i_dbNSFP_LR_score	i_dbNSFP_MutationAssessor_pred	i_dbNSFP_MutationAssessor_rankscore	i_dbNSFP_MutationAssessor_score	i_dbNSFP_MutationTaster_converted_rankscore	i_dbNSFP_MutationTaster_pred	i_dbNSFP_MutationTaster_score	i_dbNSFP_Polyphen2_HDIV_pred	i_dbNSFP_Polyphen2_HDIV_rankscore	i_dbNSFP_Polyphen2_HDIV_score	i_dbNSFP_Polyphen2_HVAR_pred	i_dbNSFP_Polyphen2_HVAR_rankscore	i_dbNSFP_Polyphen2_HVAR_score	i_dbNSFP_RadialSVM_pred	i_dbNSFP_RadialSVM_rankscore	i_dbNSFP_RadialSVM_score	i_dbNSFP_Reliability_index	i_dbNSFP_SIFT_converted_rankscore	i_dbNSFP_SIFT_pred	i_dbNSFP_SIFT_score	i_dbNSFP_SLR_test_statistic	i_dbNSFP_SiPhy_29way_logOdds	i_dbNSFP_SiPhy_29way_logOdds_rankscore	i_dbNSFP_SiPhy_29way_pi	i_dbNSFP_UniSNP_ids	i_dbNSFP_Uniprot_aapos	i_dbNSFP_Uniprot_acc	i_dbNSFP_Uniprot_id	i_dbNSFP_aaalt	i_dbNSFP_aapos	i_dbNSFP_aapos_FATHMM	i_dbNSFP_aapos_SIFT	i_dbNSFP_aaref	i_dbNSFP_cds_strand	i_dbNSFP_codonpos	i_dbNSFP_fold-degenerate	i_dbNSFP_genename	i_dbNSFP_hg18_pos(1-coor)	i_dbNSFP_phastCons100way_vertebrate	i_dbNSFP_phastCons100way_vertebrate_rankscore	i_dbNSFP_phastCons46way_placental	i_dbNSFP_phastCons46way_placental_rankscore	i_dbNSFP_phastCons46way_primate	i_dbNSFP_phastCons46way_primate_rankscore	i_dbNSFP_phyloP100way_vertebrate	i_dbNSFP_phyloP100way_vertebrate_rankscore	i_dbNSFP_phyloP46way_placental	i_dbNSFP_phyloP46way_placental_rankscore	i_dbNSFP_phyloP46way_primate	i_dbNSFP_phyloP46way_primate_rankscore	i_dbNSFP_refcodon	i_default_gene_name_WU	i_deletion_substructures_WU	i_domain_WU	i_ensembl_gene_id	i_entrez_gene_id	i_gc_content_full	i_gencode_transcript_name	i_gencode_transcript_status	i_gencode_transcript_tags	i_gencode_transcript_type	i_gene_name_WU	i_gene_name_source_WU	i_gene_type	i_havana_transcript	i_normal_ref_reads	i_normal_vaf	i_normal_var_reads	i_reference_WU	i_refseq_mrna_id	i_secondary_variant_classification	i_start_WU	i_stop_WU	i_strand_WU	i_transcript_error_WU	i_transcript_name_WU	i_transcript_source_WU	i_transcript_species_WU	i_transcript_status_WU	i_transcript_version_WU	i_trv_type_WU	i_tumor_ref_reads	i_tumor_vaf	i_tumors_var_reads	i_type_WU	i_ucsc_cons_WU	i_variant_WU
ADCY7	113	genome.wustl.edu	37	16	50346035	50346035	+	Missense_Mutation	SNP	G	G	A			TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr16:50346035G>A	ENST00000394697.2	+	21	2877	c.2537G>A	c.(2536-2538)cGc>cAc	p.R846H	ADCY7_ENST00000254235.3_Missense_Mutation_p.R846H			P51828	ADCY7_HUMAN	adenylate cyclase 7	846					activation of phospholipase C activity (GO:0007202)|activation of protein kinase A activity (GO:0034199)|adenylate cyclase-activating G-protein coupled receptor signaling pathway (GO:0007189)|adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193)|cellular response to ethanol (GO:0071361)|cellular response to glucagon stimulus (GO:0071377)|energy reserve metabolic process (GO:0006112)|epidermal growth factor receptor signaling pathway (GO:0007173)|fibroblast growth factor receptor signaling pathway (GO:0008543)|innate immune response (GO:0045087)|intracellular signal transduction (GO:0035556)|maternal process involved in female pregnancy (GO:0060135)|neurotrophin TRK receptor signaling pathway (GO:0048011)|positive regulation of cAMP biosynthetic process (GO:0030819)|signal transduction (GO:0007165)|small molecule metabolic process (GO:0044281)|synaptic transmission (GO:0007268)|transmembrane transport (GO:0055085)|water transport (GO:0006833)	integral component of membrane (GO:0016021)|plasma membrane (GO:0005886)	adenylate cyclase activity (GO:0004016)|ATP binding (GO:0005524)|metal ion binding (GO:0046872)			breast(1)|cervix(1)|endometrium(5)|large_intestine(6)|lung(14)|ovary(1)|prostate(1)|skin(2)|stomach(1)|urinary_tract(3)	35		all_cancers(37;0.0127)		GBM - Glioblastoma multiforme(240;0.195)		AACGTGAACCGCCTTCTTCTG	0.557																																						dbGAP											0													112.0	100.0	104.0					16																	50346035		2198	4300	6498	-	-	-	SO:0001583	missense	0			D25538	CCDS10741.1, CCDS73882.1	16q12.1	2013-02-04			ENSG00000121281	ENSG00000121281	4.6.1.1	"""Adenylate cyclases"""	238	protein-coding gene	gene with protein product		600385				7860067	Standard	NM_001286057		Approved	KIAA0037, AC7	uc002egd.1	P51828	OTTHUMG00000133172	ENST00000394697.2:c.2537G>A	16.37:g.50346035G>A	ENSP00000378187:p.Arg846His		A0AVA6	Missense_Mutation	SNP	pfam_A/G_cyclase,pfam_Adenylate_cyclase-like,superfamily_A/G_cyclase,smart_A/G_cyclase,pfscan_A/G_cyclase	p.R846H	ENST00000394697.2	37	c.2537	CCDS10741.1	16	.	.	.	.	.	.	.	.	.	.	G	16.48	3.136004	0.56936	.	.	ENSG00000121281	ENST00000394697;ENST00000254235	D;D	0.82893	-1.66;-1.66	4.77	3.74	0.42951	Adenylyl cyclase class-3/4/guanylyl cyclase (1);	0.166477	0.25189	U	0.032477	T	0.78898	0.4356	M	0.67700	2.07	0.80722	D	1	P	0.36412	0.552	B	0.33690	0.168	T	0.81017	-0.1123	10	0.62326	D	0.03	.	9.9169	0.41439	0.1684:0.0:0.8316:0.0	.	846	P51828	ADCY7_HUMAN	H	846	ENSP00000378187:R846H;ENSP00000254235:R846H	ENSP00000254235:R846H	R	+	2	0	ADCY7	48903536	1.000000	0.71417	1.000000	0.80357	0.976000	0.68499	6.551000	0.73909	2.470000	0.83445	0.462000	0.41574	CGC	ADCY7	-	smart_A/G_cyclase	ENSG00000121281		0.557	ADCY7-001	KNOWN	basic|appris_principal|CCDS	protein_coding	ADCY7	HGNC	protein_coding	OTTHUMT00000256877.3	51	0.00	0	G			50346035	50346035	+1	no_errors	ENST00000254235	ensembl	human	known	69_37n	missense	50	19.70	13	SNP	1.000	A
ADCYAP1R1	117	genome.wustl.edu	37	7	31146206	31146206	+	Missense_Mutation	SNP	G	G	A	rs184507640		TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr7:31146206G>A	ENST00000304166.4	+	16	1604	c.1315G>A	c.(1315-1317)Ggg>Agg	p.G439R	ADCYAP1R1_ENST00000409489.1_Missense_Mutation_p.G495R|ADCYAP1R1_ENST00000396211.2_Missense_Mutation_p.G467R|ADCYAP1R1_ENST00000409363.1_Missense_Mutation_p.G418R	NM_001118.4|NM_001199635.1|NM_001199636.1	NP_001109.2|NP_001186564.1|NP_001186565.1	P41586	PACR_HUMAN	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	439					activation of adenylate cyclase activity (GO:0007190)|cell differentiation (GO:0030154)|cell surface receptor signaling pathway (GO:0007166)|multicellular organismal development (GO:0007275)|neurotrophin TRK receptor signaling pathway (GO:0048011)|spermatogenesis (GO:0007283)|transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169)	integral component of plasma membrane (GO:0005887)|plasma membrane (GO:0005886)|receptor complex (GO:0043235)	receptor activity (GO:0004872)|vasoactive intestinal polypeptide receptor activity (GO:0004999)			endometrium(1)|large_intestine(4)|liver(2)|lung(24)|ovary(1)|skin(2)|stomach(1)	35						GGCCAGCAGTGGGGTGAATGG	0.587													G|||	1	0.000199681	0.0	0.0	5008	,	,		20128	0.0		0.001	False		,,,				2504	0.0				Ovarian(44;225 1186 2158 11092)	dbGAP											0													109.0	94.0	100.0					7																	31146206		2203	4300	6503	-	-	-	SO:0001583	missense	0				CCDS5433.1, CCDS56480.1, CCDS56481.1	7p14.3	2012-09-20			ENSG00000078549	ENSG00000078549		"""GPCR / Class B : VIP and PACAP (ADCYAP1) receptors"""	242	protein-coding gene	gene with protein product	"""PACAP receptor 1"""	102981				7902709	Standard	NM_001199635		Approved	PAC1, PACAPR, PAC1R	uc003tcg.3	P41586	OTTHUMG00000023884	ENST00000304166.4:c.1315G>A	7.37:g.31146206G>A	ENSP00000306620:p.Gly439Arg		A8K1Y1|B7ZLA7|B8ZZK3|Q17S10	Missense_Mutation	SNP	pfam_GPCR_2_secretin-like,pfam_GPCR_2_extracellular_dom,smart_GPCR_2_extracellular_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,prints_GPCR_2_PACAP_1_rcpt,prints_GPCR_2_secretin-like	p.G439R	ENST00000304166.4	37	c.1315	CCDS5433.1	7	1	4.578754578754579E-4	0	0.0	0	0.0	0	0.0	1	0.0013192612137203166	G	28.0	4.882913	0.91740	.	.	ENSG00000078549	ENST00000304166;ENST00000409363;ENST00000396211;ENST00000409489	T;T;T;T	0.63255	-0.03;-0.03;-0.03;-0.03	4.99	4.99	0.66335	.	0.000000	0.85682	D	0.000000	T	0.76256	0.3962	M	0.64170	1.965	0.80722	D	1	D;D;D;D;D	0.89917	1.0;0.999;1.0;0.999;0.999	D;D;D;D;D	0.97110	1.0;0.979;1.0;0.969;0.969	T	0.75528	-0.3286	10	0.41790	T	0.15	.	16.137	0.81492	0.0:0.0:1.0:0.0	.	466;467;495;418;439	B7ZLA7;Q17S10;E9PFU5;B8ZZK3;P41586	.;.;.;.;PACR_HUMAN	R	439;418;467;495	ENSP00000306620:G439R;ENSP00000387335:G418R;ENSP00000379514:G467R;ENSP00000386395:G495R	ENSP00000306620:G439R	G	+	1	0	ADCYAP1R1	31112731	1.000000	0.71417	1.000000	0.80357	0.999000	0.98932	7.965000	0.87945	2.495000	0.84180	0.655000	0.94253	GGG	ADCYAP1R1	-	prints_GPCR_2_PACAP_1_rcpt	ENSG00000078549		0.587	ADCYAP1R1-001	KNOWN	basic|appris_candidate|CCDS	protein_coding	ADCYAP1R1	HGNC	protein_coding	OTTHUMT00000215041.3	53	0.00	0	G	NM_001118		31146206	31146206	+1	no_errors	ENST00000304166	ensembl	human	known	69_37n	missense	86	14.00	14	SNP	1.000	A
ATP13A4	84239	genome.wustl.edu	37	3	193174938	193174938	+	Missense_Mutation	SNP	G	G	A	rs373348467		TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr3:193174938G>A	ENST00000342695.4	-	16	2088	c.1766C>T	c.(1765-1767)cCa>cTa	p.P589L	ATP13A4_ENST00000392443.3_Missense_Mutation_p.P570L	NM_032279.2	NP_115655.2	Q4VNC1	AT134_HUMAN	ATPase type 13A4	589						integral component of membrane (GO:0016021)	ATP binding (GO:0005524)|cation-transporting ATPase activity (GO:0019829)|metal ion binding (GO:0046872)			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(9)|lung(27)|ovary(2)|prostate(3)|skin(11)|upper_aerodigestive_tract(2)	71	all_cancers(143;1.76e-08)|Ovarian(172;0.0386)		OV - Ovarian serous cystadenocarcinoma(49;2.72e-18)|LUSC - Lung squamous cell carcinoma(58;3.55e-06)|Lung(62;4.19e-06)	GBM - Glioblastoma multiforme(46;0.000109)		TCCTTCCACTGGGACCTGGTT	0.463																																						dbGAP											0													114.0	102.0	106.0					3																	193174938		2203	4300	6503	-	-	-	SO:0001583	missense	0			AK095277	CCDS3304.2	3q29	2010-04-20			ENSG00000127249	ENSG00000127249		"""ATPases / P-type"""	25422	protein-coding gene	gene with protein product		609556				14702039, 12975309	Standard	XM_005247829		Approved	DKFZp761I1011, FLJ37958	uc003ftd.3	Q4VNC1	OTTHUMG00000074067	ENST00000342695.4:c.1766C>T	3.37:g.193174938G>A	ENSP00000339182:p.Pro589Leu		B7WPC7|Q6UY23|Q8N1Q9|Q9H043	Nonsense_Mutation	SNP	pfam_ATPase_P-typ_ATPase-assoc-dom,pfam_Dehalogen-like_hydro,superfamily_HAD-like_dom,superfamily_ATPase_cation_domN,prints_ATPase_P-typ_ion-transptr,prints_ATPase_P-typ_cation-exchng_asu,tigrfam_ATPase_P-typ_unknown-pump-sp,tigrfam_ATPase_P-typ_ion-transptr	p.Q229*	ENST00000342695.4	37	c.685	CCDS3304.2	3	.	.	.	.	.	.	.	.	.	.	G	20.9	4.060242	0.76074	.	.	ENSG00000127249	ENST00000392443;ENST00000342695	T;T	0.66815	-0.23;-0.23	5.86	5.86	0.93980	ATPase, cation-transporting, domain N (1);ATPase, P-type, cytoplasmic domain N (1);	0.094831	0.47455	D	0.000240	T	0.68201	0.2975	L	0.46670	1.46	0.80722	D	1	P;P;P	0.41848	0.763;0.579;0.763	P;B;P	0.48571	0.464;0.333;0.582	T	0.70306	-0.4908	10	0.72032	D	0.01	-15.4257	12.4736	0.55801	0.0757:0.0:0.9243:0.0	.	570;589;589	B7WPN9;Q4VNC1-2;Q4VNC1	.;.;AT134_HUMAN	L	570;589	ENSP00000376238:P570L;ENSP00000339182:P589L	ENSP00000339182:P589L	P	-	2	0	ATP13A4	194657632	1.000000	0.71417	0.994000	0.49952	0.973000	0.67179	6.082000	0.71318	2.778000	0.95560	0.655000	0.94253	CCA	ATP13A4	-	pfam_Dehalogen-like_hydro,superfamily_ATPase_cation_domN,tigrfam_ATPase_P-typ_unknown-pump-sp	ENSG00000127249		0.463	ATP13A4-003	KNOWN	basic|appris_principal|CCDS	protein_coding	ATP13A4	HGNC	protein_coding	OTTHUMT00000157244.4	60	0.00	0	G	NM_032279		193174938	193174938	-1	pseudogene:no_stop_codon:bad_bp_length_for_coding_region	ENST00000428352	ensembl	human	known	69_37n	nonsense	46	29.23	19	SNP	0.989	A
BNC2	54796	genome.wustl.edu	37	9	16552596	16552596	+	Missense_Mutation	SNP	C	C	T			TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr9:16552596C>T	ENST00000380672.4	-	5	658	c.601G>A	c.(601-603)Gag>Aag	p.E201K	BNC2_ENST00000545497.1_Missense_Mutation_p.E106K|BNC2_ENST00000380667.2_Missense_Mutation_p.E134K|BNC2_ENST00000380666.2_Missense_Mutation_p.E201K	NM_017637.5	NP_060107.3			basonuclin 2											NS(2)|breast(3)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(16)|liver(1)|lung(22)|ovary(2)|prostate(1)|skin(1)|urinary_tract(2)	60				GBM - Glioblastoma multiforme(50;9.01e-08)		TGCAGTACCTCCTCTTGCTTC	0.572																																						dbGAP											0													108.0	79.0	89.0					9																	16552596		2203	4300	6503	-	-	-	SO:0001583	missense	0			AK092247	CCDS6482.2	9p22.2	2013-05-20			ENSG00000173068	ENSG00000173068		"""Zinc fingers, C2H2-type"""	30988	protein-coding gene	gene with protein product		608669				14702039	Standard	XM_006716784		Approved	BSN2, FLJ20043	uc003zml.3	Q6ZN30	OTTHUMG00000019593	ENST00000380672.4:c.601G>A	9.37:g.16552596C>T	ENSP00000370047:p.Glu201Lys			Missense_Mutation	SNP	smart_Znf_C2H2-like,pfscan_Znf_C2H2	p.E201K	ENST00000380672.4	37	c.601	CCDS6482.2	9	.	.	.	.	.	.	.	.	.	.	C	37	6.138068	0.97315	.	.	ENSG00000173068	ENST00000380672;ENST00000418777;ENST00000456672;ENST00000436939;ENST00000380667;ENST00000545497;ENST00000544198;ENST00000380666;ENST00000540340	T;T;T;T;T	0.03772	3.81;3.81;3.81;3.81;3.81	6.08	6.08	0.98989	.	0.000000	0.85682	D	0.000000	T	0.23054	0.0557	M	0.67953	2.075	0.80722	D	1	D;P;D;D;D;D;D	0.89917	0.999;0.915;0.992;0.996;1.0;0.993;0.965	D;P;D;D;D;D;P	0.91635	0.995;0.608;0.984;0.99;0.999;0.956;0.696	T	0.00005	-1.2538	10	0.72032	D	0.01	-22.3333	20.6721	0.99693	0.0:1.0:0.0:0.0	.	106;134;238;201;27;159;201	F5H586;B1APH0;Q06HC4;Q6ZN30-2;B4E3J2;Q5H9S4;Q6ZN30	.;.;.;.;.;.;BNC2_HUMAN	K	201;158;238;229;134;106;27;201;201	ENSP00000370047:E201K;ENSP00000408370:E158K;ENSP00000370042:E134K;ENSP00000444640:E106K;ENSP00000370041:E201K	ENSP00000370041:E201K	E	-	1	0	BNC2	16542596	1.000000	0.71417	1.000000	0.80357	0.983000	0.72400	7.818000	0.86416	2.894000	0.99253	0.591000	0.81541	GAG	BNC2	-	NULL	ENSG00000173068		0.572	BNC2-008	KNOWN	basic|appris_candidate_longest|CCDS	protein_coding	BNC2	HGNC	protein_coding	OTTHUMT00000216901.5	36	0.00	0	C	NM_017637		16552596	16552596	-1	no_errors	ENST00000380672	ensembl	human	known	69_37n	missense	42	22.22	12	SNP	1.000	T
LINC00200	399706	genome.wustl.edu	37	10	1205771	1205771	+	lincRNA	SNP	T	T	C	rs55923937		TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr10:1205771T>C	ENST00000425630.1	+	0	64					NR_015376.2				long intergenic non-protein coding RNA 200																		ACGCTTTGCGTAGATGAGGGA	0.657																																						dbGAP											0													15.0	19.0	17.0					10																	1205771		691	1591	2282	-	-	-			0			AK097673		10p15.3	2012-10-12	2011-08-11	2011-08-11	ENSG00000229205	ENSG00000229205		"""Long non-coding RNAs"""	30974	non-coding RNA	RNA, long non-coding			"""chromosome 10 open reading frame 139"", ""non-protein coding RNA 200"""	C10orf139, NCRNA00200			Standard	NR_015376		Approved	FLJ40354	uc010qag.1		OTTHUMG00000017539		10.37:g.1205771T>C				RNA	SNP	-	NULL	ENST00000425630.1	37	NULL		10																																																																																			LINC00200	-	-	ENSG00000229205		0.657	LINC00200-001	KNOWN	basic	lincRNA	LINC00200	HGNC	lincRNA	OTTHUMT00000046417.2	19	0.00	0	T	NR_015376		1205771	1205771	+1	no_errors	ENST00000425630	ensembl	human	known	69_37n	rna	17	19.05	4	SNP	0.020	C
NPIPB15	440348	genome.wustl.edu	37	16	74411912	74411912	+	Missense_Mutation	SNP	G	G	A	rs62055194	byFrequency	TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr16:74411912G>A	ENST00000429990.1	+	1	137	c.41G>A	c.(40-42)gGa>gAa	p.G14E				A6NHN6	NPB15_HUMAN	nuclear pore complex interacting protein family, member B15	14						extracellular region (GO:0005576)		p.G14E(1)									CTCCTGCTGGGATTTATCAGC	0.597																																						dbGAP											1	Substitution - Missense(1)	prostate(1)											4.0	3.0	3.0					16																	74411912		1306	2173	3479	-	-	-	SO:0001583	missense	0			BC160029		16q22.3	2013-06-11	2013-06-11	2013-06-11	ENSG00000196436	ENSG00000196436			34409	protein-coding gene	gene with protein product			"""nuclear pore complex interacting protein-like 2"""	NPIPL2			Standard	XM_005256273		Approved	LOC440348	uc010vmt.1	A6NHN6	OTTHUMG00000156916	ENST00000429990.1:c.41G>A	16.37:g.74411912G>A	ENSP00000411140:p.Gly14Glu		C9J9U8	Missense_Mutation	SNP	pfam_NPIP	p.G14E	ENST00000429990.1	37	c.41		16	.	.	.	.	.	.	.	.	.	.	g	5.413	0.261372	0.10239	.	.	ENSG00000196436	ENST00000429990	T	0.59224	0.28	.	.	.	.	.	.	.	.	T	0.47322	0.1439	L	0.34521	1.04	0.09310	N	1	.	.	.	.	.	.	T	0.46162	-0.9211	5	0.87932	D	0	.	.	.	.	rs62055194	14	A6NHN6	NPPL2_HUMAN	E	14	ENSP00000411140:G14E	ENSP00000411140:G14E	G	+	2	0	NPIPL2	72969413	0.092000	0.21681	0.092000	0.20876	0.092000	0.18411	0.064000	0.14437	0.064000	0.16427	0.064000	0.15345	GGA	NPIPL2	-	pfam_NPIP	ENSG00000196436		0.597	NPIPB15-001	KNOWN	basic|appris_principal	protein_coding	NPIPL2	HGNC	protein_coding	OTTHUMT00000346597.2	14	0.00	0	G	NM_001018059		74411912	74411912	+1	no_errors	ENST00000429990	ensembl	human	known	69_37n	missense	13	38.10	8	SNP	0.091	A
PRR12	57479	genome.wustl.edu	37	19	50098208	50098208	+	Missense_Mutation	SNP	G	G	A			TCGA-AR-A24W-01A-11D-A17G-09	TCGA-AR-A24W-10A-01D-A167-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1		Illumina GAIIx	454e7cd4-8424-4cad-8fbb-f69affa5d1bf	781a3f88-4ca5-4f67-bcef-dcfe30dced42	g.chr19:50098208G>A	ENST00000418929.2	+	4	628	c.616G>A	c.(616-618)Gag>Aag	p.E206K		NM_020719.1	NP_065770.1	Q9ULL5	PRR12_HUMAN	proline rich 12	0	Pro-rich.						DNA binding (GO:0003677)			NS(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(2)|pancreas(1)|prostate(2)	11		all_lung(116;2.45e-07)|Lung NSC(112;1.24e-06)|Ovarian(192;0.0728)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00319)|GBM - Glioblastoma multiforme(134;0.0132)		ACTGGGCTTCGAGCGCCTGGC	0.701																																						dbGAP											0													12.0	14.0	13.0					19																	50098208		1908	4087	5995	-	-	-	SO:0001583	missense	0			AB033031	CCDS46143.1	19q13.33	2008-07-02	2006-02-06	2006-02-06		ENSG00000126464			29217	protein-coding gene	gene with protein product			"""KIAA1205"""	KIAA1205		10574462	Standard	NM_020719		Approved		uc002poo.4	Q9ULL5		ENST00000418929.2:c.616G>A	19.37:g.50098208G>A	ENSP00000394510:p.Glu206Lys		E9PB06|Q8N4J6	Missense_Mutation	SNP	NULL	p.E206K	ENST00000418929.2	37	c.616	CCDS46143.1	19	.	.	.	.	.	.	.	.	.	.	G	13.02	2.110900	0.37242	.	.	ENSG00000126464	ENST00000418929	.	.	.	3.5	3.5	0.40072	.	.	.	.	.	T	0.46833	0.1413	.	.	.	0.38128	D	0.938079	D	0.56521	0.976	B	0.40741	0.339	T	0.60449	-0.7261	7	0.54805	T	0.06	.	14.319	0.66473	0.0:0.0:1.0:0.0	.	206	Q9ULL5-3	.	K	206	.	ENSP00000394510:E206K	E	+	1	0	PRR12	54790020	1.000000	0.71417	0.997000	0.53966	0.596000	0.36781	8.996000	0.93539	1.986000	0.57962	0.563000	0.77884	GAG	PRR12	-	NULL	ENSG00000126464		0.701	PRR12-001	NOVEL	basic|appris_principal|CCDS	protein_coding	PRR12	HGNC	protein_coding	OTTHUMT00000465915.1	24	0.00	0	G	NM_020719		50098208	50098208	+1	no_errors	ENST00000418929	ensembl	human	known	69_37n	missense	16	30.43	7	SNP	1.000	A
