Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
HFM1	164045	broad.mit.edu	37	1	91843657	91843657	+	Silent	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:91843657C>T	uc001doa.4	-	10	1419	c.1320G>A	c.(1318-1320)caG>caA	p.Q440Q	HFM1_uc010osu.2_Silent_p.Q119Q|HFM1_uc010osv.1_Silent_p.Q124Q|HFM1_uc001doc.1_Silent_p.Q440Q	NM_001017975	NP_001017975	A2PYH4	HFM1_HUMAN	Homo sapiens HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) (HFM1), mRNA.	440	Helicase ATP-binding.						ATP binding|ATP-dependent helicase activity|nucleic acid binding			breast(4)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(17)|lung(33)|ovary(1)|prostate(3)|skin(2)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	75		all_lung(203;0.00961)|Lung NSC(277;0.0351)		all cancers(265;0.000481)|Epithelial(280;0.00863)|OV - Ovarian serous cystadenocarcinoma(397;0.126)|KIRC - Kidney renal clear cell carcinoma(1967;0.171)		TTTTTAAAGTCTGAGAAACAG	0.368												
LINGO4	339398	broad.mit.edu	37	1	151774511	151774511	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:151774511G>A	uc001ezf.1	-	1	860	c.670C>T	c.(670-672)Ctg>Ttg	p.L224L	LINGO4_uc021oyu.1_Silent_p.L224L	NM_001004432	NP_001004432	Q6UY18	LIGO4_HUMAN	Homo sapiens leucine rich repeat and Ig domain containing 4 (LINGO4), mRNA.	224						integral to membrane				breast(2)|cervix(1)|endometrium(4)|large_intestine(5)|lung(4)|ovary(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	21	Hepatocellular(266;0.0877)|all_hematologic(923;0.127)|Melanoma(130;0.14)		LUSC - Lung squamous cell carcinoma(543;0.181)			AGCCCCCGCAGGGCCCCAGCT	0.642												
FLG2	388698	broad.mit.edu	37	1	152324558	152324559	+	Frame_Shift_Del	DEL	TG	TG	-	rs140875805	byFrequency	TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:152324558_152324559delTG	uc001ezw.4	-	2	5776_5777	c.5703_5704delCA	c.(5701-5706)cacagcfs	p.H1901fs	AK056431_uc001ezv.3_Intron	NM_001014342	NP_001014364	Q5D862	FILA2_HUMAN	Homo sapiens filaggrin family member 2 (FLG2), mRNA.	1901							calcium ion binding|structural molecule activity	p.H1901fs*30(2)		NS(2)|breast(7)|cervix(3)|endometrium(11)|kidney(9)|large_intestine(24)|liver(1)|lung(85)|ovary(12)|pancreas(1)|prostate(6)|skin(17)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(5)	188	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			CTGGCTTGGCTGTGTGTGTGTC	0.515												
UBQLN4	56893	broad.mit.edu	37	1	156011962	156011962	+	Silent	SNP	G	G	C			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:156011962G>C	uc001fna.3	-	7	1356	c.1332C>G	c.(1330-1332)ctC>ctG	p.L444L	UBQLN4_uc010pgx.2_Silent_p.L424L	NM_020131	NP_064516	Q9NRR5	UBQL4_HUMAN	Homo sapiens ubiquilin 4 (UBQLN4), mRNA.	444						cytosol|endoplasmic reticulum membrane|nucleus	identical protein binding			NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|kidney(1)|large_intestine(1)|lung(6)|pancreas(1)|skin(2)	16	Hepatocellular(266;0.133)|all_neural(408;0.195)					GGAAGACTGGGAGCTGCAGGC	0.617												
UBQLN4	56893	broad.mit.edu	37	1	156021545	156021545	+	Missense_Mutation	SNP	C	C	G			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:156021545C>G	uc001fna.3	-	1	236	c.212G>C	c.(211-213)gGa>gCa	p.G71A	UBQLN4_uc010pgx.2_Missense_Mutation_p.G71A|LAMTOR2_uc001fnb.3_5'Flank|LAMTOR2_uc010pgy.1_5'Flank	NM_020131	NP_064516	Q9NRR5	UBQL4_HUMAN	Homo sapiens ubiquilin 4 (UBQLN4), mRNA.	71	Ubiquitin-like.					cytosol|endoplasmic reticulum membrane|nucleus	identical protein binding	p.G71R(1)		NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|kidney(1)|large_intestine(1)|lung(6)|pancreas(1)|skin(2)	16	Hepatocellular(266;0.133)|all_neural(408;0.195)					GTCCTTGATTCCGTGCTGGTT	0.537												
IQGAP3	128239	broad.mit.edu	37	1	156501015	156501015	+	Missense_Mutation	SNP	G	G	C			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:156501015G>C	uc001fpf.3	-	32	4203	c.4128C>G	c.(4126-4128)atC>atG	p.I1376M		NM_178229	NP_839943	Q86VI3	IQGA3_HUMAN	Homo sapiens IQ motif containing GTPase activating protein 3 (IQGAP3), mRNA.	1376					small GTPase mediated signal transduction	intracellular	calmodulin binding|Ras GTPase activator activity			NS(1)|breast(2)|central_nervous_system(1)|endometrium(8)|kidney(2)|large_intestine(14)|lung(29)|ovary(5)|prostate(5)|skin(5)|urinary_tract(3)	75	all_hematologic(923;0.088)|Hepatocellular(266;0.158)					GGAACTGTATGATATCGGCCA	0.587												
NTRK1	4914	broad.mit.edu	37	1	156834161	156834161	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:156834161G>A	uc001fqh.1	+	1	284	c.228G>A	c.(226-228)caG>caA	p.Q76Q	NTRK1_uc001fqf.1_Silent_p.Q46Q|NTRK1_uc009wsi.1_5'UTR|NTRK1_uc001fqi.1_Silent_p.Q76Q|NTRK1_uc009wsk.1_Silent_p.Q76Q	NM_002529	NP_002520	P04629	NTRK1_HUMAN	Homo sapiens neurotrophic tyrosine kinase, receptor, type 1 (NTRK1), transcript variant 2, mRNA.	76					activation of adenylate cyclase activity|activation of MAPKK activity|activation of phospholipase C activity|cell differentiation|nerve growth factor receptor signaling pathway|nervous system development|phosphatidylinositol-mediated signaling|Ras protein signal transduction	endosome|integral to plasma membrane	ATP binding|neurotrophin receptor activity|transmembrane receptor protein serine/threonine kinase activity|transmembrane receptor protein tyrosine kinase activity			breast(3)|central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(7)|lung(35)|ovary(8)|prostate(2)|skin(5)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	74	all_hematologic(923;0.0839)|Hepatocellular(266;0.158)				Imatinib(DB00619)	TCGAGAACCAGCAGCATCTGC	0.597			T	"""TPM3, TPR, TFG"""	papillary thyroid					TSP Lung(10;0.080)		
ARHGEF11	9826	broad.mit.edu	37	1	156917714	156917714	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:156917714C>T	uc001fqo.3	-	23	3108	c.2068G>A	c.(2068-2070)Gat>Aat	p.D690N	ARHGEF11_uc010phu.2_Missense_Mutation_p.D106N|ARHGEF11_uc001fqn.3_Missense_Mutation_p.D730N	NM_014784	NP_055599	O15085	ARHGB_HUMAN	Homo sapiens Rho guanine nucleotide exchange factor (GEF) 11 (ARHGEF11), transcript variant 1, mRNA.	690					actin cytoskeleton organization|apoptosis|axon guidance|cellular component movement|cytokinesis|establishment of cell polarity|G-protein coupled receptor protein signaling pathway|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|positive regulation of transcription, DNA-dependent|regulation of cell growth|regulation of Rho protein signal transduction|Rho protein signal transduction|striated muscle contraction	cytosol|Golgi apparatus|plasma membrane	G-protein-coupled receptor binding|GTPase activator activity|Rho guanyl-nucleotide exchange factor activity|signal transducer activity			NS(1)|breast(3)|central_nervous_system(3)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(15)|lung(27)|ovary(4)|pancreas(2)|pleura(1)|prostate(4)|skin(7)|stomach(1)|urinary_tract(2)	81	all_hematologic(923;0.0839)|Hepatocellular(266;0.158)					AGGAGGGTATCTGTGCAGAAC	0.562												
F5	2153	broad.mit.edu	37	1	169489788	169489788	+	Nonsense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:169489788G>A	uc001ggg.1	-	21	6308	c.6163C>T	c.(6163-6165)Cga>Tga	p.R2055*		NM_000130	NP_000121	P12259	FA5_HUMAN	Homo sapiens coagulation factor V (proaccelerin, labile factor) (F5), mRNA.	2055	F5/8 type C 1.				cell adhesion|platelet activation|platelet degranulation	plasma membrane|platelet alpha granule lumen	copper ion binding|oxidoreductase activity			NS(1)|breast(4)|central_nervous_system(4)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(24)|lung(55)|ovary(3)|prostate(4)|skin(5)|stomach(1)|upper_aerodigestive_tract(7)|urinary_tract(1)	128	all_hematologic(923;0.208)				Drotrecogin alfa(DB00055)	AGTTCCAATCGAAGGGTAGGT	0.403												
LGR6	59352	broad.mit.edu	37	1	202287759	202287759	+	Silent	SNP	C	C	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:202287759C>A	uc001gxu.3	+	17	2328	c.2328C>A	c.(2326-2328)gcC>gcA	p.A776A	LGR6_uc001gxv.3_Silent_p.A724A|LGR6_uc009xab.3_Non-coding_Transcript|LGR6_uc001gxw.3_Silent_p.A637A	NM_001017403	NP_001017403	Q9HBX8	LGR6_HUMAN	Homo sapiens leucine-rich repeat containing G protein-coupled receptor 6 (LGR6), transcript variant 1, mRNA.	776						integral to membrane|plasma membrane	protein-hormone receptor activity			breast(1)|endometrium(3)|kidney(1)|large_intestine(5)|lung(16)|ovary(3)|pancreas(1)|prostate(3)|skin(3)	36						GGCACGTGGCCTGGCTCATCT	0.637												
RASSF5	83593	broad.mit.edu	37	1	206711530	206711530	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:206711530C>T	uc001hed.3	+	1	544	c.487C>T	c.(487-489)Cgc>Tgc	p.R163C	RASSF5_uc001hec.1_Missense_Mutation_p.R163C|RASSF5_uc001hee.3_Missense_Mutation_p.R163C	NM_182663	NP_872604	Q8WWW0	RASF5_HUMAN	Homo sapiens Ras association (RalGDS/AF-6) domain family member 5 (RASSF5), transcript variant 1, mRNA.	163					apoptosis|intracellular signal transduction	cytoplasm|microtubule	metal ion binding|protein binding			endometrium(1)|kidney(1)|large_intestine(3)|lung(2)|ovary(1)	8	Breast(84;0.183)		BRCA - Breast invasive adenocarcinoma(75;0.166)			CCCAGAATGCCGCAGCCTGAT	0.532												
MAPKAPK2	9261	broad.mit.edu	37	1	206902080	206902080	+	Missense_Mutation	SNP	G	G	A	rs151079567		TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:206902080G>A	uc001hem.2	+	1	515	c.305G>A	c.(304-306)cGc>cAc	p.R102H	MAPKAPK2_uc001hel.2_Missense_Mutation_p.R102H	NM_032960	NP_116584	P49137	MAPK2_HUMAN	Homo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), transcript variant 2, mRNA.	102	Protein kinase.				activation of MAPK activity|hormone biosynthetic process|innate immune response|leukotriene biosynthetic process|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|nerve growth factor receptor signaling pathway|prostanoid metabolic process|Ras protein signal transduction|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|nucleoplasm	ATP binding|protein binding|protein serine/threonine kinase activity|signal transducer activity			central_nervous_system(1)|endometrium(1)|large_intestine(4)|lung(8)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	19	Breast(84;0.183)		BRCA - Breast invasive adenocarcinoma(75;0.211)			CCCAAGGCCCGCAGGGAGGTG	0.622												
ESRRG	2104	broad.mit.edu	37	1	216737723	216737723	+	Splice_Site	SNP	C	C	G			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr1:216737723C>G	uc001hkw.2	-	5	874	c.701_splice	c.e5-1	p.Y234_splice	ESRRG_uc009xdp.1_Splice_Site_p.Y211_splice|ESRRG_uc001hky.1_Splice_Site_p.Y211_splice|ESRRG_uc001hkz.2_Splice_Site_p.Y172_splice|ESRRG_uc010puc.2_Splice_Site_p.Y211_splice|ESRRG_uc001hla.2_Splice_Site_p.Y211_splice|ESRRG_uc001hlb.2_Splice_Site_p.Y211_splice|ESRRG_uc010pud.2_Splice_Site_p.Y49_splice|ESRRG_uc021pja.1_Splice_Site|ESRRG_uc001hlc.1_Splice_Site_p.Y211_splice|ESRRG_uc001hld.1_Splice_Site_p.Y211_splice|ESRRG_uc001hkx.2_Missense_Mutation_p.D246H|ESRRG_uc009xdo.2_Splice_Site_p.Y211_splice|ESRRG_uc001hle.2_Splice_Site_p.Y211_splice|ESRRG_uc021piz.1_Splice_Site_p.Y211_splice	NM_001438	NP_001230435	P62508	ERR3_HUMAN	Homo sapiens estrogen-related receptor gamma (ESRRG), transcript variant 1, mRNA.	234					positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor	nucleoplasm	AF-2 domain binding|retinoic acid receptor activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|steroid hormone receptor activity|zinc ion binding			endometrium(5)|kidney(1)|large_intestine(8)|liver(1)|lung(29)|ovary(1)|skin(2)|stomach(1)|urinary_tract(1)	49				OV - Ovarian serous cystadenocarcinoma(81;0.0358)|all cancers(67;0.0693)|GBM - Glioblastoma multiforme(131;0.0713)	Diethylstilbestrol(DB00255)	ATCTTGTTATCTGCAGGATCA	0.433												
AKR1E2	83592	broad.mit.edu	37	10	4873008	4873008	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr10:4873008C>T	uc001ihi.3	+	1	296	c.181C>T	c.(181-183)Cgg>Tgg	p.R61W	AKR1E2_uc010qam.1_Missense_Mutation_p.R61W|AKR1E2_uc001ihh.1_Missense_Mutation_p.R61W|AKR1E2_uc001ihj.3_Non-coding_Transcript|AKR1E2_uc001ihk.3_Missense_Mutation_p.R61W|AKR1E2_uc009xhw.3_Missense_Mutation_p.R61W	NM_001040177	NP_001035267	Q96JD6	AKCL2_HUMAN	Homo sapiens aldo-keto reductase family 1, member E2 (AKR1E2), mRNA.	61						cytoplasm	1,5-anhydro-D-fructose reductase activity	p.R61W(2)|p.R61L(1)|p.R61R(1)		NS(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(9)	15						CGCTGTAAGACGGGAGGATCT	0.507												
ITIH2	3698	broad.mit.edu	37	10	7762869	7762869	+	Silent	SNP	C	C	T	rs144114794		TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr10:7762869C>T	uc001ijs.3	+	6	843	c.681C>T	c.(679-681)ccC>ccT	p.P227P		NM_002216	NP_002207	P19823	ITIH2_HUMAN	Homo sapiens inter-alpha-trypsin inhibitor heavy chain 2 (ITIH2), mRNA.	227					hyaluronan metabolic process	extracellular region	serine-type endopeptidase inhibitor activity	p.P227P(2)		NS(2)|breast(1)|endometrium(8)|kidney(1)|large_intestine(17)|lung(25)|ovary(1)|pancreas(1)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	64						TTCATGTTCCCGACACATTTG	0.453												
C10orf68	79741	broad.mit.edu	37	10	33000595	33000595	+	Missense_Mutation	SNP	T	T	C			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr10:33000595T>C	uc001iwm.1	+	4	591	c.355T>C	c.(355-357)Tca>Cca	p.S119P	C10orf68_uc001iwl.1_Missense_Mutation_p.S151P|C10orf68_uc001iwn.4_Missense_Mutation_p.S143P|C10orf68_uc010qei.1_Missense_Mutation_p.S70P	NM_024688	NP_078964	Q9H943	CJ068_HUMAN	Homo sapiens chromosome 10 open reading frame 68 (C10orf68), mRNA.	143										breast(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(15)|ovary(1)|skin(4)	29						ACATCAAGATTCAGTGTCAAA	0.308												
NAV3	89795	broad.mit.edu	37	12	78591133	78591133	+	Missense_Mutation	SNP	C	C	G			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr12:78591133C>G	uc001syp.3	+	34	6571	c.6398C>G	c.(6397-6399)tCt>tGt	p.S2133C	NAV3_uc001syo.3_Missense_Mutation_p.S2111C|NAV3_uc010sub.2_Missense_Mutation_p.S1590C|NAV3_uc009zsf.3_Missense_Mutation_p.S942C	NM_014903	NP_055718	Q8IVL0	NAV3_HUMAN	Homo sapiens neuron navigator 3 (NAV3), mRNA.	2133						nuclear outer membrane	ATP binding|nucleoside-triphosphatase activity	p.T2133S(1)		NS(2)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(13)|kidney(16)|large_intestine(39)|liver(2)|lung(126)|ovary(5)|pancreas(3)|prostate(6)|skin(5)|stomach(2)|upper_aerodigestive_tract(8)|urinary_tract(1)	236						CATGTGGGCTCTCTGAGTGAT	0.328										HNSCC(70;0.22)		
PAWR	5074	broad.mit.edu	37	12	80014954	80014954	+	Nonsense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr12:80014954G>A	uc001syx.3	-	2	836	c.550C>T	c.(550-552)Cag>Tag	p.Q184*		NM_002583	NP_002574	Q96IZ0	PAWR_HUMAN	Homo sapiens PRKC, apoptosis, WT1, regulator (PAWR), mRNA.	184	Selective for apoptosis induction in cancer cells (SAC).				actin filament bundle assembly|apoptosis|induction of apoptosis|negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|nucleus|plasma membrane	actin binding|enzyme binding|leucine zipper domain binding|transcription corepressor activity			NS(1)|large_intestine(1)|lung(4)|ovary(1)|skin(1)	8						CGCTCTTTCTGCCCTGCTTCA	0.363												
FRY	10129	broad.mit.edu	37	13	32735289	32735289	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr13:32735289G>A	uc001utx.3	+	16	2289	c.1793G>A	c.(1792-1794)aGa>aAa	p.R598K	FRY_uc010tdw.2_Non-coding_Transcript	NM_023037	NP_075463	Q5TBA9	FRY_HUMAN	Homo sapiens furry homolog (Drosophila) (FRY), mRNA.	598					regulation of transcription, DNA-dependent|transcription, DNA-dependent	integral to membrane				NS(3)|breast(4)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(31)|lung(50)|ovary(5)|pancreas(1)|prostate(6)|skin(9)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	132		Lung SC(185;0.0271)		all cancers(112;4.81e-05)|Epithelial(112;0.000656)|OV - Ovarian serous cystadenocarcinoma(117;0.0123)|BRCA - Breast invasive adenocarcinoma(63;0.0295)|GBM - Glioblastoma multiforme(144;0.104)		AGGGGTGAGAGAAAGCCAAAA	0.358												
FARP1	10160	broad.mit.edu	37	13	99042246	99042246	+	Silent	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr13:99042246C>T	uc001vnh.3	+	9	1130	c.891C>T	c.(889-891)gcC>gcT	p.A297A	FARP1_uc001vnj.3_Silent_p.A297A	NM_005766	NP_005757	Q9Y4F1	FARP1_HUMAN	Homo sapiens FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) (FARP1), transcript variant 1, mRNA.	297	FERM.				regulation of Rho protein signal transduction	cytoplasm|cytoskeleton|extrinsic to membrane	cytoskeletal protein binding|Rho guanyl-nucleotide exchange factor activity			breast(3)|endometrium(6)|kidney(6)|large_intestine(13)|lung(16)|ovary(1)|skin(3)|urinary_tract(1)	49	all_neural(89;0.0982)|Medulloblastoma(90;0.163)|Lung SC(71;0.184)		BRCA - Breast invasive adenocarcinoma(86;0.233)			TCCTGATGGCCAGTCGGGATT	0.443												
UNC79	57578	broad.mit.edu	37	14	94041533	94041533	+	Missense_Mutation	SNP	G	G	C			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr14:94041533G>C	uc001ybv.1	+	13	1752	c.1669G>C	c.(1669-1671)Gca>Cca	p.A557P	UNC79_uc001ybs.1_Missense_Mutation_p.A557P	NM_020818	NP_065869	Q9P2D8	UNC79_HUMAN	Homo sapiens unc-79 homolog (C. elegans) (UNC79), mRNA.	734						integral to membrane		p.V557I(1)		breast(3)|cervix(2)|endometrium(10)|kidney(7)|large_intestine(18)|liver(1)|lung(64)|ovary(1)|prostate(5)|skin(3)|urinary_tract(4)	118						AGGGAACCTTGCATCTCGAAG	0.373												
GOLGA8F	100132565	broad.mit.edu	37	15	28629364	28629364	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr15:28629364G>A	uc010uag.1	+	8	787	c.663G>A	c.(661-663)ctG>ctA	p.L221L	GOLGA8F_uc001zbn.2_Silent_p.L15L|GOLGA8F_uc001zbp.3_Silent_p.L15L|DQ600342_uc001zbq.3_5'Flank|DQ578838_uc021sgk.1_5'Flank					Homo sapiens golgin A8 family, member F (GOLGA8F), non-coding RNA.											lung(4)	4						AGGCACTGCTGAAAGCGCAGC	0.542												
CHD2	1106	broad.mit.edu	37	15	93567832	93567834	+	In_Frame_Del	DEL	CTC	CTC	-			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr15:93567832_93567834delCTC	uc002bsp.3	+	38	5959_5961	c.5384_5386delCTC	c.(5383-5388)tctcct>tct	p.P1796del		NM_001271	NP_001262	O14647	CHD2_HUMAN	Homo sapiens chromodomain helicase DNA binding protein 2 (CHD2), transcript variant 1, mRNA.	1796					regulation of transcription from RNA polymerase II promoter	nucleus	ATP binding|ATP-dependent DNA helicase activity|DNA binding			breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(5)|kidney(2)|large_intestine(10)|lung(17)|ovary(1)|prostate(2)|skin(2)|stomach(1)|urinary_tract(2)	47	Lung NSC(78;0.00976)|all_lung(78;0.016)		BRCA - Breast invasive adenocarcinoma(143;0.0282)|OV - Ovarian serous cystadenocarcinoma(32;0.0814)			TCTCAGAAATCTCCTCACGATTC	0.468												
UBFD1	56061	broad.mit.edu	37	16	23570883	23570883	+	Silent	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr16:23570883C>T	uc002dlv.3	+	2	652	c.450C>T	c.(448-450)atC>atT	p.I150I	EARS2_uc002dls.4_5'Flank|EARS2_uc002dlt.4_5'Flank|EARS2_uc002dlu.3_5'Flank	NM_019116	NP_061989	O14562	UBFD1_HUMAN	Homo sapiens ubiquitin family domain containing 1 (UBFD1), mRNA.	150	Ubiquitin-like.									endometrium(1)|kidney(1)|large_intestine(2)|lung(3)	7				GBM - Glioblastoma multiforme(48;0.0331)		GGGCCAAGATCATGGTGGTTG	0.502												
RNMTL1	55178	broad.mit.edu	37	17	695048	695048	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr17:695048G>A	uc002frw.3	+	3	1108	c.1002G>A	c.(1000-1002)ctG>ctA	p.L334L		NM_018146	NP_060616	Q9HC36	RMTL1_HUMAN	Homo sapiens RNA methyltransferase like 1 (RNMTL1), mRNA.	334					RNA processing		protein binding|RNA binding|RNA methyltransferase activity			breast(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(1)|ovary(2)|prostate(1)|upper_aerodigestive_tract(1)	10				UCEC - Uterine corpus endometrioid carcinoma (25;0.0219)		AAGATTGGCTGCCTCATGTTG	0.552												
ALDH3A1	218	broad.mit.edu	37	17	19641725	19641725	+	Missense_Mutation	SNP	C	C	T	rs113168621		TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr17:19641725C>T	uc002gwk.3	-	7	1872	c.1609G>A	c.(1609-1611)Gag>Aag	p.E537K	ALDH3A1_uc010cqu.3_Missense_Mutation_p.E420K|ALDH3A1_uc010vzd.2_Missense_Mutation_p.E420K|ALDH3A1_uc002gwj.3_Missense_Mutation_p.E420K|ALDH3A1_uc010cqv.3_Missense_Mutation_p.E419K|ALDH3A1_uc002gwl.1_Missense_Mutation_p.E347K			P30838	AL3A1_HUMAN	Homo sapiens aldehyde dehydrogenase 3 family, member A1 (ALDH3A1), transcript variant 2, mRNA.	420					cellular aldehyde metabolic process	cytosol|endoplasmic reticulum	alcohol dehydrogenase (NADP+) activity|aldehyde dehydrogenase|aldehyde dehydrogenase (NAD) activity			breast(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(4)|ovary(1)|pancreas(1)|urinary_tract(1)	13	all_cancers(12;4.01e-05)|all_epithelial(12;0.00301)|Breast(13;0.186)			Colorectal(15;0.0829)	NADH(DB00157)	GAGAAAGTCTCGAAGCTCTTC	0.612												
GAS2L2	246176	broad.mit.edu	37	17	34072169	34072169	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr17:34072169G>A	uc002hjv.2	-	5	2375	c.2347C>T	c.(2347-2349)Cgg>Tgg	p.R783W		NM_139285	NP_644814	Q8NHY3	GA2L2_HUMAN	Homo sapiens growth arrest-specific 2 like 2 (GAS2L2), mRNA.	783					cell cycle arrest	cytoplasm|cytoskeleton				central_nervous_system(1)|endometrium(1)|large_intestine(7)|lung(14)|ovary(2)|pancreas(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	35		Ovarian(249;0.17)		UCEC - Uterine corpus endometrioid carcinoma (308;0.0182)		TGGTCTCTCCGGGGCCGAATC	0.612												
USH1G	124590	broad.mit.edu	37	17	72915620	72915620	+	Silent	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr17:72915620C>T	uc002jme.1	-	1	1494	c.1311G>A	c.(1309-1311)aaG>aaA	p.K437K	USH1G_uc010wro.1_Silent_p.K334K	NM_173477	NP_775748	Q495M9	USH1G_HUMAN	Homo sapiens Usher syndrome 1G (autosomal recessive) (USH1G), mRNA.	437	SAM.				equilibrioception|photoreceptor cell maintenance|sensory perception of sound	actin cytoskeleton			HN1/USH1G(2)	endometrium(1)|kidney(1)|large_intestine(4)|lung(4)|prostate(1)|skin(3)	14	all_lung(278;0.172)|Lung NSC(278;0.207)					CCAAGATCTTCTTTCGGGGCC	0.682												
INO80C	125476	broad.mit.edu	37	18	33060423	33060423	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr18:33060423G>A	uc010dmt.3	-	3	486	c.369C>T	c.(367-369)aaC>aaT	p.N123N	INO80C_uc002kyw.1_Silent_p.N87N|INO80C_uc002kyx.4_Silent_p.N32N|INO80C_uc002kyy.4_Silent_p.N87N	NM_001098817	NP_001092287	Q6PI98	IN80C_HUMAN	Homo sapiens INO80 complex subunit C (INO80C), transcript variant 1, mRNA.	87					DNA recombination|DNA repair|regulation of transcription, DNA-dependent|transcription, DNA-dependent	Ino80 complex|MLL1 complex				central_nervous_system(1)|endometrium(1)|lung(3)|prostate(2)|skin(1)	8						TTACCACAAAGTTGGGATCCT	0.483												
SERPINB3	6318	broad.mit.edu	37	18	61310407	61310407	+	Silent	SNP	A	A	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr18:61310407A>T	uc002ljf.3	-	2	296	c.210T>A	c.(208-210)gcT>gcA	p.A70A	SERPINB3_uc002lje.3_Silent_p.A70A|SERPINB3_uc002ljg.3_Intron	NM_002974	NP_002965	P29508	SPB3_HUMAN	Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 4 (SERPINB4), mRNA.	70					regulation of proteolysis	cytoplasm|extracellular region	protein binding|serine-type endopeptidase inhibitor activity			breast(2)|central_nervous_system(1)|endometrium(4)|kidney(3)|large_intestine(4)|lung(14)|ovary(1)|skin(5)|upper_aerodigestive_tract(2)	36						GATATGTTGCAGCTTTTTCTG	0.403												
CNDP1	84735	broad.mit.edu	37	18	72223637	72223637	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr18:72223637C>T	uc002llq.3	+	1	300	c.89C>T	c.(88-90)cCg>cTg	p.P30L		NM_032649	NP_116038	Q96KN2	CNDP1_HUMAN	Homo sapiens carnosine dipeptidase 1 (metallopeptidase M20 family) (CNDP1), mRNA.	30					proteolysis	extracellular region	carboxypeptidase activity|dipeptidase activity|metal ion binding|metallopeptidase activity|tripeptidase activity	p.S29F(1)		breast(1)|central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(4)|lung(12)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	27		Esophageal squamous(42;0.129)|Prostate(75;0.157)|Melanoma(33;0.211)		BRCA - Breast invasive adenocarcinoma(31;0.109)		TCACCCTCCCCGCCCCCGGCG	0.537												
SAFB2	9667	broad.mit.edu	37	19	5587916	5587916	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr19:5587916G>A	uc002mcd.3	-	18	2813	c.2601C>T	c.(2599-2601)gaC>gaT	p.D867D		NM_014649	NP_055464	Q14151	SAFB2_HUMAN	Homo sapiens scaffold attachment factor B2 (SAFB2), mRNA.	867	Gly-rich.|Interacts with SAFB1.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding|nucleotide binding|protein binding|RNA binding			endometrium(3)|kidney(4)|large_intestine(7)|lung(8)|ovary(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29				UCEC - Uterine corpus endometrioid carcinoma (162;0.000228)		CCGCGCCTGCGTCCATGGCAC	0.672												
FBN3	84467	broad.mit.edu	37	19	8190851	8190851	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr19:8190851C>T	uc002mjf.3	-	20	2673	c.2656G>A	c.(2656-2658)Gtc>Atc	p.V886I		NM_032447	NP_115823	Q75N90	FBN3_HUMAN	Homo sapiens fibrillin 3 (FBN3), mRNA.	886	EGF-like 11; calcium-binding.					proteinaceous extracellular matrix	calcium ion binding|extracellular matrix structural constituent			NS(1)|breast(9)|central_nervous_system(2)|cervix(1)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(15)|lung(53)|ovary(7)|pancreas(2)|prostate(3)|skin(10)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	132						GCAGTGTTGACGCAACGCCCG	0.637												
MAU2	23383	broad.mit.edu	37	19	19459728	19459728	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr19:19459728G>A	uc002nmk.4	+	13	1378	c.1339G>A	c.(1339-1341)Gac>Aac	p.D447N	MAU2_uc002nml.4_Missense_Mutation_p.D52N|MAU2_uc010ecd.3_Missense_Mutation_p.D52N|MAU2_uc010ece.3_Missense_Mutation_p.D23N	NM_015329	NP_056144	Q9Y6X3	SCC4_HUMAN	Homo sapiens MAU2 chromatid cohesion factor homolog (C. elegans) (MAU2), mRNA.	447					cell division|maintenance of mitotic sister chromatid cohesion	chromatin|nucleoplasm|SMC loading complex	protein N-terminus binding			NS(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(5)|skin(1)|upper_aerodigestive_tract(1)	18						GATCAACCCGGACCACAGCTT	0.617												
MYH14	79784	broad.mit.edu	37	19	50792885	50792885	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr19:50792885C>T	uc010enu.1	+	34	4992	c.4945C>T	c.(4945-4947)Cgg>Tgg	p.R1649W	MYH14_uc002prq.1_Missense_Mutation_p.R1616W|MYH14_uc002prr.1_Missense_Mutation_p.R1608W|MYH14_uc010ycb.2_5'UTR|MYH14_uc002prs.1_5'UTR	NM_001145809	NP_001139281	Q7Z406	MYH14_HUMAN	Homo sapiens myosin, heavy chain 14, non-muscle (MYH14), transcript variant 3, mRNA.	1608					axon guidance|regulation of cell shape	myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			central_nervous_system(1)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(10)|ovary(1)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	46		all_neural(266;0.0571)|Ovarian(192;0.0728)		OV - Ovarian serous cystadenocarcinoma(262;0.00389)|GBM - Glioblastoma multiforme(134;0.0195)		TGAAGAGAGGCGGAGGCAGCT	0.612												
TSSC1	7260	broad.mit.edu	37	2	3193249	3193249	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr2:3193249G>A	uc002qxj.2	-	8	1213	c.1020C>T	c.(1018-1020)atC>atT	p.I340I	TSSC1_uc002qxi.2_Non-coding_Transcript	NM_003310	NP_003301	Q53HC9	TSSC1_HUMAN	Homo sapiens tumor suppressing subtransferable candidate 1 (TSSC1), mRNA.	340							protein binding			breast(2)|kidney(2)|large_intestine(3)|lung(9)|prostate(1)|skin(1)	18	Acute lymphoblastic leukemia(172;0.0627)|all_hematologic(175;0.093)	all_cancers(51;0.212)		OV - Ovarian serous cystadenocarcinoma(76;0.00877)|Epithelial(75;0.0283)|all cancers(51;0.0464)		CGTAGGTGGCGATCACGTTGT	0.657												
MAP4K4	9448	broad.mit.edu	37	2	102486218	102486218	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr2:102486218G>A	uc002tbc.3	+	21	2976	c.2598G>A	c.(2596-2598)ggG>ggA	p.G866G	MAP4K4_uc002tbf.3_Silent_p.G755G|MAP4K4_uc002tbd.3_Silent_p.G758G|MAP4K4_uc010yvy.2_Silent_p.G781G|MAP4K4_uc002tbh.3_Silent_p.G703G|MAP4K4_uc002tbg.3_Silent_p.G785G|MAP4K4_uc002tbi.3_Silent_p.G588G|MAP4K4_uc010yvz.2_Silent_p.G761G|MAP4K4_uc002tbk.3_Silent_p.G240G|MAP4K4_uc021vlq.1_5'UTR|MAP4K4_uc002tbl.3_5'UTR	NM_145687	NP_001229488	O95819	M4K4_HUMAN	Homo sapiens mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4), transcript variant 3, mRNA.	785	Mediates interaction with RAP2A.				intracellular protein kinase cascade|regulation of JNK cascade|response to stress	cytoplasm	ATP binding|protein binding|protein serine/threonine kinase activity|small GTPase regulator activity			breast(1)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(8)|lung(15)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	41						AGCAGGAAGGGGCTGACGAGT	0.572												
ALS2CR8	79800	broad.mit.edu	37	2	203806678	203806678	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr2:203806678C>T	uc002uzo.2	+	2	333	c.53C>T	c.(52-54)tCa>tTa	p.S18L	ALS2CR8_uc002uzn.3_Intron|ALS2CR8_uc002uzm.3_Missense_Mutation_p.S18L|ALS2CR8_uc010zhy.1_Missense_Mutation_p.S18L|ALS2CR8_uc010zhz.1_Intron|ALS2CR8_uc010ftu.1_Intron|ALS2CR8_uc010zia.1_Missense_Mutation_p.S18L|ALS2CR8_uc010zib.1_Missense_Mutation_p.S18L|ALS2CR8_uc010zic.1_Intron|ALS2CR8_uc002uzp.2_Missense_Mutation_p.S18L	NM_001104586	NP_079020	Q8N187	AL2S8_HUMAN	Homo sapiens amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 (ALS2CR8), mRNA.	18										breast(1)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(5)|lung(6)|ovary(1)|pancreas(2)|prostate(1)|skin(1)	20						GGTGAAGAGTCAAAAACCAGT	0.363												
RASSF2	9770	broad.mit.edu	37	20	4776462	4776462	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr20:4776462C>T	uc002wld.3	-	4	341	c.287_splice	c.e4+1	p.G96_splice	RASSF2_uc002wlc.3_5'Flank|RASSF2_uc002wlf.3_Splice_Site_p.G96_splice	NM_170774	NP_739580	P50749	RASF2_HUMAN	Homo sapiens Ras association (RalGDS/AF-6) domain family member 2 (RASSF2), transcript variant 2, mRNA.	96					cell cycle|signal transduction	nucleus	protein binding			endometrium(3)|kidney(2)|large_intestine(8)|lung(12)|ovary(3)|pancreas(2)|prostate(2)|skin(2)	34						CTCACTCACCCCTGAGCCCCC	0.597												
TXNRD2	10587	broad.mit.edu	37	22	19865620	19865620	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr22:19865620C>T	uc021wlj.1	-	15	1471	c.1438G>A	c.(1438-1440)Ggg>Agg	p.G480R	TXNRD2_uc002zqo.1_Non-coding_Transcript|TXNRD2_uc002zqr.1_Missense_Mutation_p.G479R|TXNRD2_uc002zqj.1_Non-coding_Transcript|TXNRD2_uc002zqq.1_Missense_Mutation_p.G130R	NM_006440		Q9NNW7	TRXR2_HUMAN	Homo sapiens thioredoxin reductase 2 (TXNRD2), nuclear gene encoding mitochondrial protein, mRNA.	480					cell redox homeostasis|response to oxygen radical	mitochondrion	flavin adenine dinucleotide binding|NADP binding|thioredoxin-disulfide reductase activity			breast(1)|endometrium(7)|kidney(1)|large_intestine(4)|lung(12)|ovary(3)|urinary_tract(2)	30	Colorectal(54;0.0993)					TACTTGATCCCCAGAGCAAAT	0.597												
SMTN	6525	broad.mit.edu	37	22	31492853	31492853	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr22:31492853G>A	uc003ajl.2	+	13	2237	c.1996G>A	c.(1996-1998)Gtt>Att	p.V666I	SMTN_uc003ajk.2_Missense_Mutation_p.V666I|SMTN_uc003ajm.2_Missense_Mutation_p.V666I|SMTN_uc011ale.2_Missense_Mutation_p.V751I|SMTN_uc011alf.2_Missense_Mutation_p.V722I|SMTN_uc003ajn.2_Missense_Mutation_p.V689I|SMTN_uc011alg.2_Missense_Mutation_p.V122I|SMTN_uc003ajo.2_Intron|SMTN_uc011alh.1_Non-coding_Transcript|SMTN_uc010gwe.2_Intron	NM_006932	NP_008863	P53814	SMTN_HUMAN	Homo sapiens smoothelin (SMTN), transcript variant 3, mRNA.	666					muscle organ development|smooth muscle contraction	actin cytoskeleton|cytoplasm	actin binding|structural constituent of muscle			breast(2)|endometrium(2)|large_intestine(5)|lung(9)|ovary(3)|pancreas(1)|prostate(3)	25						TGTCAGCACTGTTACCAAGAC	0.682												
MST1	4485	broad.mit.edu	37	3	49723522	49723522	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr3:49723522G>A	uc003cxg.3	-	8	1192	c.1120C>T	c.(1120-1122)Cgt>Tgt	p.R374C	MST1_uc011bcs.1_Silent_p.G412G|MST1_uc010hkx.2_3'UTR|MST1_uc011bct.1_3'UTR	NM_020998	NP_066278	P26927	HGFL_HUMAN	Homo sapiens macrophage stimulating 1 (hepatocyte growth factor-like) (MST1), mRNA.	360	Kringle 4.				proteolysis	extracellular region	serine-type endopeptidase activity	p.R360C(2)		NS(4)|breast(1)|central_nervous_system(1)|endometrium(10)|kidney(1)|large_intestine(1)|lung(9)|prostate(2)|skin(9)|stomach(1)|urinary_tract(2)	41				BRCA - Breast invasive adenocarcinoma(193;4.47e-05)|Kidney(197;0.00216)|KIRC - Kidney renal clear cell carcinoma(197;0.00244)		TCTGTACAACGCCGGATCTGG	0.697												
ABI3BP	25890	broad.mit.edu	37	3	100568897	100568897	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr3:100568897G>A	uc003dun.3	-	14	1452	c.1367C>T	c.(1366-1368)aCg>aTg	p.T456M	ABI3BP_uc003duo.2_Missense_Mutation_p.T498M	NM_015429	NP_056244	Q7Z7G0	TARSH_HUMAN	Homo sapiens ABI family, member 3 (NESH) binding protein (ABI3BP), mRNA.	456	Pro-rich.					extracellular space				central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(13)|lung(18)|ovary(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	50						ACCAGGTGTCGTAGGCTGCAT	0.378												
MYH15	22989	broad.mit.edu	37	3	108205332	108205332	+	Frame_Shift_Del	DEL	A	A	-			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr3:108205332delA	uc003dxa.1	-	10	1030	c.973delT	c.(973-975)tgcfs	p.C325fs		NM_014981	NP_055796	Q9Y2K3	MYH15_HUMAN	Homo sapiens myosin, heavy chain 15 (MYH15), mRNA.	325	Myosin head-like.					myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|motor activity			NS(1)|breast(3)|central_nervous_system(2)|cervix(4)|endometrium(10)|kidney(4)|large_intestine(14)|lung(47)|ovary(5)|pancreas(2)|prostate(6)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	105						CCACAGGAGCAAAAGTGGAAG	0.438												
ZIC1	7545	broad.mit.edu	37	3	147128425	147128425	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr3:147128425G>A	uc003ewe.3	+	0	1245	c.526G>A	c.(526-528)Gag>Aag	p.E176K		NM_003412	NP_003403	Q15915	ZIC1_HUMAN	Homo sapiens Zic family member 1 (ZIC1), mRNA.	176					behavior|brain development|cell differentiation|inner ear morphogenesis|pattern specification process|positive regulation of protein import into nucleus|positive regulation of transcription, DNA-dependent|regulation of smoothened signaling pathway	cytoplasm|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			central_nervous_system(4)|cervix(1)|endometrium(2)|large_intestine(8)|lung(38)|ovary(1)|prostate(4)|upper_aerodigestive_tract(4)|urinary_tract(1)	63						CCCGCGACCGGAGCAGTACGG	0.682												
POU4F2	5458	broad.mit.edu	37	4	147561770	147561770	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr4:147561770G>A	uc003ikv.3	+	1	1288	c.1040G>A	c.(1039-1041)cGc>cAc	p.R347H		NM_004575	NP_004566	Q12837	PO4F2_HUMAN	Homo sapiens POU class 4 homeobox 2 (POU4F2), mRNA.	347					estrogen receptor signaling pathway|MAPKKK cascade|negative regulation of transcription from RNA polymerase II promoter	nuclear speck	RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	p.R347C(1)		NS(1)|breast(1)|endometrium(7)|kidney(3)|large_intestine(11)|lung(8)|skin(1)|upper_aerodigestive_tract(1)	33	all_hematologic(180;0.151)					GAGAAGAAGCGCAAGCGCACG	0.622												
ZDHHC11	79844	broad.mit.edu	37	5	825284	825284	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr5:825284C>T	uc011cma.1	-	7	1402	c.1018G>A	c.(1018-1020)Gca>Aca	p.A340T	ZDHHC11_uc010itc.3_5'Flank|ZDHHC11_uc010itd.1_Non-coding_Transcript	NM_024786	NP_079062	Q9H8X9	ZDH11_HUMAN	Homo sapiens zinc finger, DHHC-type containing 11 (ZDHHC11), mRNA.	340						integral to membrane	acyltransferase activity|zinc ion binding			haematopoietic_and_lymphoid_tissue(1)|liver(1)|lung(10)|pancreas(1)|prostate(5)|skin(2)|urinary_tract(1)	21			Epithelial(17;0.000445)|all cancers(22;0.00176)|OV - Ovarian serous cystadenocarcinoma(19;0.00227)|Lung(60;0.0863)			CTTACCCGTGCCGTCGAATCC	0.542												
HTR1A	3350	broad.mit.edu	37	5	63257205	63257205	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr5:63257205G>A	uc011cqt.2	-	0	342	c.342C>T	c.(340-342)gcC>gcT	p.A114A		NM_000524	NP_000515	P08908	5HT1A_HUMAN	Homo sapiens 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A), mRNA.	114					behavior|positive regulation of cell proliferation	integral to plasma membrane	serotonin receptor activity			cervix(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(11)|lung(29)|ovary(2)|pancreas(2)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	56		Lung NSC(810;3.55e-06)|Prostate(74;0.0352)|Ovarian(174;0.0545)|Breast(144;0.0575)|Colorectal(97;0.234)		Lung(70;0.105)	Alprenolol(DB00866)|Aripiprazole(DB01238)|Buspirone(DB00490)|Clozapine(DB00363)|Eletriptan(DB00216)|Ergoloid mesylate(DB01049)|Fluvoxamine(DB00176)|Lisuride(DB00589)|Methysergide(DB00247)|Mirtazapine(DB00370)|Pindolol(DB00960)|Propranolol(DB00571)|Quetiapine(DB01224)|Sertraline(DB01104)|Tegaserod(DB01079)|Trazodone(DB00656)|Venlafaxine(DB00285)|Ziprasidone(DB00246)	GCACGTCGAGGGCGATGAACA	0.607												
PCDHAC2	56143	broad.mit.edu	37	5	140203141	140203141	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr5:140203141G>A	uc003lhl.2	+	0	1781	c.1781G>A	c.(1780-1782)cGc>cAc	p.R594H	PCDHAC2_uc003lha.2_Intron|PCDHAC2_uc003lhb.2_Intron|PCDHAC2_uc003lhd.2_Intron|PCDHAC2_uc003lhf.2_Intron|PCDHAC2_uc003lhh.1_Intron|PCDHAC2_uc003lhi.2_Intron|PCDHAC2_uc003lhk.1_Missense_Mutation_p.R594H|PCDHAC2_uc003lhj.1_Missense_Mutation_p.R594H	NM_018908	NP_061731	Q9Y5I4	PCDC2_HUMAN	Homo sapiens protocadherin alpha 5 (PCDHA5), transcript variant 1, mRNA.	608	Cadherin 6.				homophilic cell adhesion|nervous system development	integral to plasma membrane	calcium ion binding			NS(1)|breast(1)|endometrium(4)|kidney(4)|large_intestine(10)|liver(2)|lung(9)|ovary(2)|prostate(1)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(1)	45			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GCGAAGGTGCGCGCAGTGGAC	0.697												
RGS14	10636	broad.mit.edu	37	5	176794018	176794018	+	Silent	SNP	C	C	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr5:176794018C>A	uc003mgh.3	+	4	648	c.466C>A	c.(466-468)Cgg>Agg	p.R156R	RGS14_uc003mgf.3_Silent_p.R156R|RGS14_uc003mgg.1_Silent_p.R3R|RGS14_uc003mgi.3_5'Flank	NM_006480	NP_006471	O43566	RGS14_HUMAN	Homo sapiens regulator of G-protein signaling 14 (RGS14), mRNA.	156	RGS.				chromosome segregation|long-term memory|long-term synaptic potentiation|negative regulation of ERK1 and ERK2 cascade|negative regulation of MAP kinase activity|negative regulation of synaptic plasticity|nucleocytoplasmic transport|platelet-derived growth factor receptor signaling pathway|positive regulation of neurogenesis|regulation of DNA-dependent transcription in response to stress|regulation of G-protein coupled receptor protein signaling pathway|response to oxidative stress|spindle organization|visual learning|zygote asymmetric cell division	cell junction|centrosome|dendritic spine|microtubule|PML body|postsynaptic density|postsynaptic membrane|spindle pole	GDP-dissociation inhibitor activity|GTPase activator activity|microtubule binding|receptor signaling complex scaffold activity|receptor signaling protein activity			breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(3)|skin(3)|upper_aerodigestive_tract(1)	12	all_cancers(89;2.04e-05)|Renal(175;0.000269)|Lung NSC(126;0.000832)|all_lung(126;0.00152)	all_neural(177;0.00409)|Medulloblastoma(196;0.00498)|all_hematologic(541;0.21)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			GGACATGTTTCGGGCACAGCA	0.662												
PTK7	5754	broad.mit.edu	37	6	43109925	43109925	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr6:43109925G>A	uc011dve.1	+	12	2001	c.1959G>A	c.(1957-1959)caG>caA	p.Q653Q	PTK7_uc003oub.1_Silent_p.Q645Q|PTK7_uc003ouc.1_Intron|PTK7_uc003oud.1_Silent_p.Q605Q|PTK7_uc003oue.1_Silent_p.Q515Q|PTK7_uc003ouf.1_Non-coding_Transcript|PTK7_uc003oug.1_Non-coding_Transcript|PTK7_uc010jyj.1_Intron	NM_002821	NP_002812	Q13308	PTK7_HUMAN	Homo sapiens PTK7 protein tyrosine kinase 7 (PTK7), transcript variant PTK7-1, mRNA.	645	Ig-like C2-type 7.				actin cytoskeleton reorganization|canonical Wnt receptor signaling pathway|cell adhesion|cell migration	cell-cell junction|integral to plasma membrane	ATP binding|transmembrane receptor protein tyrosine kinase activity			NS(1)|breast(4)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|lung(12)|ovary(2)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	46			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.00784)|OV - Ovarian serous cystadenocarcinoma(102;0.0423)			ACATCTTCCAGAATGGCTCCC	0.642												
SRF	6722	broad.mit.edu	37	6	43141721	43141721	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr6:43141721C>T	uc003oui.3	+	1	1125	c.650C>T	c.(649-651)aCc>aTc	p.T217I	SRF_uc011dvf.2_Missense_Mutation_p.T13I	NM_003131	NP_003122	P11831	SRF_HUMAN	Homo sapiens serum response factor (c-fos serum response element-binding transcription factor) (SRF), mRNA.	217	Involved in dimerization.				angiogenesis involved in wound healing|cell migration involved in sprouting angiogenesis|cellular senescence|heart looping|muscle cell homeostasis|neuron development|positive regulation of cell differentiation|positive regulation of smooth muscle contraction|positive regulation of transcription initiation from RNA polymerase II promoter|positive regulation of transcription via serum response element binding|regulation of smooth muscle cell differentiation|response to cytokine stimulus|response to hormone stimulus|response to toxin|transcription from RNA polymerase II promoter|trophectodermal cell differentiation	endoplasmic reticulum	protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|serum response element binding|transcription factor binding			breast(1)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(3)|lung(2)|ovary(1)	12			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.011)|OV - Ovarian serous cystadenocarcinoma(102;0.0423)			CTGATTCAGACCTGCCTCAAC	0.557												
DST	667	broad.mit.edu	37	6	56566691	56566691	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr6:56566691G>A	uc021zay.1	-	4	562	c.436C>T	c.(436-438)Cgc>Tgc	p.R146C	DST_uc011dxl.1_Missense_Mutation_p.R135C|DST_uc021zaz.1_Missense_Mutation_p.R106C	NM_001723	NP_001714	Q03001	DYST_HUMAN	Homo sapiens dystonin (DST), transcript variant 1e, mRNA.	106	Actin-binding.				cell adhesion|cell cycle arrest|cell motility|hemidesmosome assembly|integrin-mediated signaling pathway|intermediate filament cytoskeleton organization|maintenance of cell polarity|microtubule cytoskeleton organization|response to wounding	actin cytoskeleton|axon|axon part|basement membrane|cell cortex|cell leading edge|cytoplasmic membrane-bounded vesicle|endoplasmic reticulum membrane|hemidesmosome|integral to membrane|intermediate filament|intermediate filament cytoskeleton|microtubule cytoskeleton|microtubule plus end|nuclear envelope|sarcomere|Z disc	actin binding|calcium ion binding|integrin binding|microtubule plus-end binding|protein binding|protein C-terminus binding|protein homodimerization activity	p.E146K(1)		NS(1)|breast(5)|central_nervous_system(8)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(22)|lung(43)|ovary(7)|prostate(1)|skin(4)|upper_aerodigestive_tract(3)	105	Lung NSC(77;0.103)		LUSC - Lung squamous cell carcinoma(124;0.0485)|Lung(124;0.0956)			CATACCTGGCGTCTTTTCAAA	0.343												
PLG	5340	broad.mit.edu	37	6	161127557	161127557	+	Silent	SNP	C	C	T	rs144100362		TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr6:161127557C>T	uc003qtm.4	+	1	280	c.168C>T	c.(166-168)gaC>gaT	p.D56D	PLG_uc021zhr.1_Silent_p.D56D	NM_000301	NP_000292	P00747	PLMN_HUMAN	Homo sapiens plasminogen (PLG), transcript variant 1, mRNA.	56	PAN.				extracellular matrix disassembly|fibrinolysis|negative regulation of cell proliferation|negative regulation of cell-substrate adhesion|negative regulation of fibrinolysis|platelet activation|platelet degranulation|positive regulation of fibrinolysis|proteolysis|tissue remodeling	extracellular space|extrinsic to external side of plasma membrane|platelet alpha granule lumen	apolipoprotein binding|cell surface binding|serine-type endopeptidase activity			NS(1)|breast(4)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|lung(19)|ovary(1)|prostate(3)|skin(9)|upper_aerodigestive_tract(1)	59				OV - Ovarian serous cystadenocarcinoma(65;5.24e-17)|BRCA - Breast invasive adenocarcinoma(81;7.08e-06)	Aminocaproic Acid(DB00513)|Streptokinase(DB00086)|Tranexamic Acid(DB00302)|Urokinase(DB00013)	GTGAGGAGGACGAAGAATTCA	0.413												
ZNF107	51427	broad.mit.edu	37	7	64168371	64168371	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr7:64168371G>A	uc003ttd.3	+	6	2475	c.1689G>A	c.(1687-1689)caG>caA	p.Q563Q	ZNF107_uc003tte.3_Silent_p.Q563Q	NM_016220	NP_057304	Q9UII5	ZN107_HUMAN	Homo sapiens zinc finger protein 107 (ZNF107), transcript variant 1, mRNA.	563					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|central_nervous_system(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(10)|lung(18)|ovary(1)|stomach(1)	37		Lung NSC(55;0.00948)|all_lung(88;0.0249)				TTTTTAACCAGTCCTCAAACC	0.348												
PCLO	27445	broad.mit.edu	37	7	82581607	82581607	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr7:82581607C>T	uc003uhx.2	-	4	8951	c.8662G>A	c.(8662-8664)Gta>Ata	p.V2888I	PCLO_uc003uhv.2_Missense_Mutation_p.V2888I|PCLO_uc010lec.3_5'Flank	NM_033026	NP_149015	Q9Y6V0	PCLO_HUMAN	Homo sapiens piccolo (presynaptic cytomatrix protein) (PCLO), transcript variant 1, mRNA.	2819					cytoskeleton organization|synaptic vesicle exocytosis	cell junction|cytoskeleton|synaptic vesicle	calcium ion binding|calcium-dependent phospholipid binding|profilin binding|transporter activity	p.T2887T(1)		breast(3)|central_nervous_system(3)|cervix(5)|endometrium(19)|haematopoietic_and_lymphoid_tissue(3)|kidney(19)|large_intestine(35)|lung(145)|ovary(7)|prostate(4)|upper_aerodigestive_tract(14)|urinary_tract(2)	259						CCCTGGGATACGGTGCTATCA	0.463												
COL1A2	1278	broad.mit.edu	37	7	94043012	94043012	+	Missense_Mutation	SNP	G	G	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr7:94043012G>T	uc003ung.1	+	26	2039	c.1568G>T	c.(1567-1569)gGt>gTt	p.G523V	COL1A2_uc011kib.1_Intron	NM_000089	NP_000080	P08123	CO1A2_HUMAN	Homo sapiens collagen, type I, alpha 2 (COL1A2), mRNA.	523					axon guidance|blood vessel development|collagen fibril organization|leukocyte migration|odontogenesis|platelet activation|regulation of blood pressure|Rho protein signal transduction|skeletal system development|skin morphogenesis|transforming growth factor beta receptor signaling pathway	collagen type I|extracellular space|plasma membrane	extracellular matrix structural constituent|identical protein binding|platelet-derived growth factor binding|protein binding, bridging	p.G523S(1)	COL1A2/PLAG1(3)	NS(2)|breast(2)|central_nervous_system(4)|cervix(1)|endometrium(6)|kidney(8)|large_intestine(21)|lung(51)|ovary(2)|prostate(1)|skin(7)|stomach(1)|upper_aerodigestive_tract(8)|urinary_tract(1)	115	all_cancers(62;2.46e-09)|all_epithelial(64;2.7e-08)		STAD - Stomach adenocarcinoma(171;0.0031)		Collagenase(DB00048)	GGTGCTCCAGGTCCTGATGGA	0.438										HNSCC(75;0.22)		
INTS10	55174	broad.mit.edu	37	8	19690804	19690804	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr8:19690804C>T	uc022asn.1	+	11	1636	c.1505C>T	c.(1504-1506)aCg>aTg	p.T502M	INTS10_uc003wzj.3_Missense_Mutation_p.T501M	NM_018142	NP_060612	Q9NVR2	INT10_HUMAN	Homo sapiens integrator complex subunit 10 (INTS10), mRNA.	501					snRNA processing	integrator complex	protein binding			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(2)|lung(8)|ovary(2)|prostate(1)|urinary_tract(1)	20				Colorectal(111;0.057)|COAD - Colon adenocarcinoma(73;0.215)		CAGCTGGCGACGTGCCACTTT	0.602												
ENPP2	5168	broad.mit.edu	37	8	120598445	120598445	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr8:120598445G>A	uc003yos.2	-	15	1590	c.1504C>T	c.(1504-1506)Cgc>Tgc	p.R502C	ENPP2_uc011lic.2_5'Flank|ENPP2_uc003yor.2_Missense_Mutation_p.R89C|ENPP2_uc010mdd.2_Missense_Mutation_p.R450C|ENPP2_uc003yot.2_Missense_Mutation_p.R450C	NM_006209	NP_006200	Q13822	ENPP2_HUMAN	Homo sapiens ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2), transcript variant 1, mRNA.	450					cellular component movement|chemotaxis|G-protein coupled receptor protein signaling pathway|immune response|phosphate metabolic process|phosphatidylcholine catabolic process|regulation of cell migration	extracellular space|integral to plasma membrane	alkylglycerophosphoethanolamine phosphodiesterase activity|calcium ion binding|lysophospholipase activity|nucleic acid binding|nucleotide diphosphatase activity|phosphodiesterase I activity|polysaccharide binding|scavenger receptor activity|transcription factor binding|zinc ion binding			breast(1)|central_nervous_system(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(15)|lung(30)|ovary(2)|prostate(2)|skin(4)|upper_aerodigestive_tract(4)	69	Lung NSC(37;5.03e-06)|Ovarian(258;0.0249)|Hepatocellular(40;0.161)		STAD - Stomach adenocarcinoma(47;0.00185)			TGCCATCTGCGTTCCACCAAT	0.413												
IFNB1	3456	broad.mit.edu	37	9	21077338	21077338	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chr9:21077338G>A	uc003zok.3	-	0	606	c.531C>T	c.(529-531)ttC>ttT	p.F177F		NM_002176	NP_002167	P01574	IFNB_HUMAN	Homo sapiens interferon, beta 1, fibroblast (IFNB1), mRNA.	177					activation of caspase activity|B cell proliferation|blood coagulation|cellular response to exogenous dsRNA|defense response to virus|induction of apoptosis|natural killer cell activation|negative regulation of cell proliferation|negative regulation of T cell differentiation|negative regulation of T-helper 2 cell cytokine production|negative regulation of viral genome replication|negative regulation of viral transcription|negative regulation of virion penetration into host cell|positive regulation of innate immune response|positive regulation of transcription from RNA polymerase II promoter|regulation of MHC class I biosynthetic process|regulation of type I interferon-mediated signaling pathway|type I interferon-mediated signaling pathway	extracellular space	cytokine activity|interferon-alpha/beta receptor binding|transcription corepressor activity			breast(3)|kidney(1)|large_intestine(1)|lung(6)|ovary(1)	12				GBM - Glioblastoma multiforme(5;7.45e-142)|Lung(24;2.42e-17)|LUSC - Lung squamous cell carcinoma(38;7.17e-11)	Interferon beta-1a(DB00060)|Interferon beta-1b(DB00068)	GTCTGTTAATGAAGTAAAAGT	0.453												
NHS	4810	broad.mit.edu	37	X	17745612	17745612	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:17745612C>T	uc011mix.2	+	6	3724	c.3386C>T	c.(3385-3387)cCg>cTg	p.P1129L	NHS_uc004cxx.3_Missense_Mutation_p.P1108L|NHS_uc004cxy.3_Missense_Mutation_p.P952L|NHS_uc004cxz.3_Missense_Mutation_p.P931L|NHS_uc004cya.3_Missense_Mutation_p.P831L	NM_001136024	NP_001129496	Q6T4R5	NHS_HUMAN	Homo sapiens Nance-Horan syndrome (congenital cataracts and dental anomalies) (NHS), transcript variant 2, mRNA.	1108						nucleus		p.P1108L(1)|p.P952L(1)		breast(5)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(17)|liver(1)|lung(26)|ovary(2)|prostate(1)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)	71	Hepatocellular(33;0.183)					AATCCTCCACCGTCCCTTGCA	0.408												
TIMM17B	10245	broad.mit.edu	37	X	48751096	48751096	+	Silent	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:48751096G>A	uc004dla.2	-	7	734	c.585C>T	c.(583-585)ccC>ccT	p.P195P	TIMM17B_uc004dlc.2_Silent_p.P145P	NM_001167947	NP_001161419	O60830	TI17B_HUMAN	Homo sapiens translocase of inner mitochondrial membrane 17 homolog B (yeast) (TIMM17B), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA.	145					protein targeting to mitochondrion	integral to membrane|microtubule cytoskeleton|mitochondrial inner membrane presequence translocase complex	P-P-bond-hydrolysis-driven protein transmembrane transporter activity			kidney(1)|large_intestine(1)|lung(3)|ovary(1)	6						CCAGGAATGGGGGCGCTGGAG	0.617												
PCDH11X	27328	broad.mit.edu	37	X	91132985	91132985	+	Missense_Mutation	SNP	C	C	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:91132985C>A	uc004efk.2	+	1	2591	c.1746C>A	c.(1744-1746)aaC>aaA	p.N582K	PCDH11X_uc004efl.2_Missense_Mutation_p.N582K|PCDH11X_uc010nmv.2_Missense_Mutation_p.N582K|PCDH11X_uc004efm.2_Missense_Mutation_p.N582K|PCDH11X_uc004efn.2_Missense_Mutation_p.N582K|PCDH11X_uc004efo.2_Missense_Mutation_p.N582K|PCDH11X_uc004efh.2_Missense_Mutation_p.N582K|PCDH11X_uc004efj.1_Missense_Mutation_p.N582K	NM_032968	NP_116750	Q9BZA7	PC11X_HUMAN	Homo sapiens protocadherin 11 X-linked (PCDH11X), transcript variant c, mRNA.	582	Cadherin 6.				homophilic cell adhesion	integral to plasma membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(30)|liver(4)|lung(92)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	159						TCCCAGAAAACCTTCCAAGGC	0.393												
DOCK11	139818	broad.mit.edu	37	X	117722099	117722099	+	Splice_Site	SNP	G	G	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:117722099G>T	uc004eqp.2	+	17	1859	c.1796_splice	c.e17-1	p.N599_splice	DOCK11_uc004eqq.2_Splice_Site_p.N365_splice	NM_144658	NP_653259	Q5JSL3	DOC11_HUMAN	Homo sapiens dedicator of cytokinesis 11 (DOCK11), mRNA.	599					blood coagulation	cytosol	GTP binding			breast(4)|cervix(2)|endometrium(8)|kidney(5)|large_intestine(17)|liver(1)|lung(35)|ovary(4)|prostate(3)|skin(3)|stomach(1)|urinary_tract(1)	84						CCCTGCTATAGATTGTATTAC	0.318												
RNF113A	7737	broad.mit.edu	37	X	119004909	119004909	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:119004909C>T	uc004esb.3	-	0	883	c.668G>A	c.(667-669)cGt>cAt	p.R223H	NDUFA1_uc004esc.4_5'Flank	NM_006978	NP_008909	O15541	R113A_HUMAN	Homo sapiens ring finger protein 113A (RNF113A), mRNA.	223							nucleic acid binding|zinc ion binding			NS(1)|breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(6)	15						GTAATCTGAACGGTCATGGAG	0.522												
ARHGAP36	158763	broad.mit.edu	37	X	130220576	130220576	+	Missense_Mutation	SNP	C	C	T			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:130220576C>T	uc004evz.3	+	10	1768	c.1423C>T	c.(1423-1425)Cca>Tca	p.P475S	ARHGAP36_uc004ewa.3_Missense_Mutation_p.P463S|ARHGAP36_uc004ewb.3_Missense_Mutation_p.P444S|ARHGAP36_uc004ewc.3_Missense_Mutation_p.P339S	NM_144967	NP_659404	Q6ZRI8	RHG36_HUMAN	Homo sapiens Rho GTPase activating protein 36 (ARHGAP36), mRNA.	475					regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol	GTPase activator activity			breast(1)|central_nervous_system(2)|endometrium(5)|kidney(3)|large_intestine(16)|lung(31)|ovary(4)|prostate(4)|skin(3)|urinary_tract(2)	71						ACTTTCTGATCCAGTGGAAAC	0.478												
CTAG2	30848	broad.mit.edu	37	X	153881755	153881755	+	Missense_Mutation	SNP	G	G	A			TCGA-19-2619-01A-01D-1495-08	TCGA-19-2619-10A-01D-1495-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	b765a4c7-4fe8-444c-95bd-6a4d03af1432	f4f9cd59-cdbd-4ee2-908b-31bb8aa6750a	g.chrX:153881755G>A	uc004fmi.2	-	0	99	c.35C>T	c.(34-36)aCg>aTg	p.T12M	CTAG2_uc004fmh.2_Missense_Mutation_p.T12M	NM_020994	NP_066274	O75638	CTAG2_HUMAN	Homo sapiens cancer/testis antigen 2 (CTAG2), transcript variant 2, mRNA.	12	Gly-rich.					centrosome				central_nervous_system(1)|endometrium(1)|lung(6)|ovary(1)|pancreas(1)	10	all_cancers(53;5.05e-16)|all_epithelial(53;1.87e-10)|all_lung(58;1.84e-07)|Lung NSC(58;5.84e-07)|all_hematologic(71;2.45e-06)|Acute lymphoblastic leukemia(192;6.56e-05)|Breast(217;0.176)					AGCATCGCCCGTCGAACCCCC	0.706												
