Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
PI4KB	5298	broad.mit.edu	37	1	151265387	151265387	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr1:151265387G>A	uc001exr.3	-	12	3067	c.2428C>T	c.(2428-2430)Cgg>Tgg	p.R810W	PI4KB_uc001exs.3_Missense_Mutation_p.R783W|PI4KB_uc001exu.3_Missense_Mutation_p.R783W|PI4KB_uc010pcw.2_Missense_Mutation_p.R466W|PI4KB_uc001ext.3_Missense_Mutation_p.R798W	NM_002651	NP_001185704	Q9UBF8	PI4KB_HUMAN	Homo sapiens phosphatidylinositol 4-kinase, catalytic, beta (PI4KB), transcript variant 1, mRNA.	798					phosphatidylinositol biosynthetic process|phosphatidylinositol-mediated signaling|receptor-mediated endocytosis	endosome|Golgi apparatus|mitochondrial outer membrane|perinuclear region of cytoplasm|rough endoplasmic reticulum membrane	1-phosphatidylinositol 4-kinase activity|ATP binding|protein binding			breast(3)|endometrium(5)|kidney(3)|large_intestine(2)|lung(7)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	27	Lung SC(34;0.00471)|Ovarian(49;0.0147)|Hepatocellular(266;0.0997)|all_hematologic(923;0.127)|Melanoma(130;0.185)		UCEC - Uterine corpus endometrioid carcinoma (35;0.112)|LUSC - Lung squamous cell carcinoma(543;0.181)			GTGATAGACCGCATACTGCCA	0.577												
DUSP27	92235	broad.mit.edu	37	1	167097496	167097496	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr1:167097496G>A	uc001geb.1	+	4	3144	c.3128G>A	c.(3127-3129)cGc>cAc	p.R1043H		NM_001080426	NP_001073895	Q5VZP5	DUS27_HUMAN	Homo sapiens dual specificity phosphatase 27 (putative) (DUSP27), mRNA.	1043					protein dephosphorylation		protein tyrosine/serine/threonine phosphatase activity	p.R1043S(1)		NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(4)|kidney(2)|large_intestine(11)|liver(1)|lung(46)|ovary(5)|prostate(5)|skin(4)|upper_aerodigestive_tract(3)	89						TACTTCTTCCGCCGGACCCCA	0.587												
TNN	63923	broad.mit.edu	37	1	175097757	175097757	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr1:175097757G>A	uc001gkl.1	+	14	3318	c.3205G>A	c.(3205-3207)Gac>Aac	p.D1069N		NM_022093	NP_071376	Q9UQP3	TENN_HUMAN	Homo sapiens tenascin N (TNN), mRNA.	1069	Fibrinogen C-terminal.				cell growth|cell migration|signal transduction	extracellular space|proteinaceous extracellular matrix				NS(1)|central_nervous_system(2)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(29)|liver(1)|lung(81)|ovary(5)|prostate(6)|skin(5)|stomach(4)|upper_aerodigestive_tract(3)|urinary_tract(3)	156		Breast(1374;0.000962)		KIRC - Kidney renal clear cell carcinoma(1967;0.00198)		ACACCCTTCGGACTGCAGTCA	0.547												
CFHR5	81494	broad.mit.edu	37	1	196964976	196964976	+	Missense_Mutation	SNP	C	C	G			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr1:196964976C>G	uc001gts.4	+	4	865	c.737C>G	c.(736-738)cCt>cGt	p.P246R		NM_030787	NP_110414	Q9BXR6	FHR5_HUMAN	Homo sapiens complement factor H-related 5 (CFHR5), mRNA.	246	Sushi 4.				complement activation, alternative pathway	extracellular region		p.G245R(1)		NS(2)|breast(2)|endometrium(2)|kidney(1)|large_intestine(7)|liver(2)|lung(23)|pancreas(1)|prostate(3)|skin(4)|upper_aerodigestive_tract(2)	49						ATAAACGGGCCTAAGAAAATA	0.333												
DDX59	83479	broad.mit.edu	37	1	200635187	200635187	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr1:200635187G>A	uc009wzk.3	-	1	925	c.682C>T	c.(682-684)Ccc>Tcc	p.P228S	DDX59_uc010ppl.1_Missense_Mutation_p.P228S	NM_001031725	NP_001026895	Q5T1V6	DDX59_HUMAN	Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 (DDX59), mRNA.	228						intracellular	ATP binding|ATP-dependent helicase activity|metal ion binding|RNA binding			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(3)|large_intestine(2)|liver(1)|lung(9)|ovary(3)	21						ATTTGAATGGGAGTTGGCACC	0.458												
PRKCQ	5588	broad.mit.edu	37	10	6470257	6470257	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr10:6470257G>A	uc001iji.1	-	16	2216	c.2132C>T	c.(2131-2133)gCc>gTc	p.A711V	PRKCQ_uc001ijj.2_Missense_Mutation_p.A678V|PRKCQ_uc009xim.2_Missense_Mutation_p.A615V|PRKCQ_uc009xin.2_Missense_Mutation_p.A642V|PRKCQ_uc010qax.2_Missense_Mutation_p.A553V	NM_006257	NP_006248	Q04759	KPCT_HUMAN	Homo sapiens protein kinase C, theta (PRKCQ), transcript variant 1, mRNA.	678					axon guidance|cellular component disassembly involved in apoptosis|intracellular signal transduction|membrane protein ectodomain proteolysis|platelet activation|regulation of cell growth|T cell receptor signaling pathway	cytosol	ATP binding|metal ion binding|protein binding|protein kinase C activity			NS(1)|breast(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(8)|liver(1)|lung(13)|ovary(4)|prostate(1)|skin(4)|stomach(2)	45						TGCTCTGTCGGCAAATGACAG	0.458												
SF1	7536	broad.mit.edu	37	11	64537812	64537812	+	Missense_Mutation	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr11:64537812C>T	uc001obb.2	-	3	757	c.305G>A	c.(304-306)cGc>cAc	p.R102H	SF1_uc010rnm.2_5'Flank|SF1_uc010rnn.2_Missense_Mutation_p.R76H|SF1_uc001oaz.2_Missense_Mutation_p.R227H|SF1_uc001oba.2_Missense_Mutation_p.R102H|SF1_uc001obd.2_Missense_Mutation_p.R102H|SF1_uc001obc.2_Missense_Mutation_p.R102H|SF1_uc001obe.2_5'UTR|SF1_uc010rno.2_5'UTR	NM_004630	NP_001171502	Q15637	SF01_HUMAN	Homo sapiens splicing factor 1 (SF1), transcript variant 1, mRNA.	102					nuclear mRNA 3'-splice site recognition|regulation of transcription, DNA-dependent|transcription, DNA-dependent	ribosome|spliceosomal complex	protein binding|RNA binding|transcription corepressor activity|zinc ion binding	p.R102H(4)		NS(1)|breast(2)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(7)|lung(12)|ovary(2)|skin(2)	31						CAGCTTTTTGCGGGTGCGGAA	0.547												
SCAF11	9169	broad.mit.edu	37	12	46320707	46320708	+	Frame_Shift_Del	DEL	TC	TC	-			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr12:46320707_46320708delTC	uc001rox.3	-	10	3063_3064	c.2776_2777delGA	c.(2776-2778)gaafs	p.E926fs	SCAF11_uc001row.3_Frame_Shift_Del_p.E611fs|SCAF11_uc001roy.1_Frame_Shift_Del_p.E1000fs	NM_004719	NP_004710	Q99590	SCAFB_HUMAN	Homo sapiens SR-related CTD-associated factor 11 (SCAF11), mRNA.	926	Arg-rich.				spliceosome assembly	nucleus	protein binding|zinc ion binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(8)|large_intestine(17)|lung(25)|ovary(3)|pancreas(1)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(3)	69						GGTTCTCCTTTCTCTCTCTCTC	0.446												
KRT7	3855	broad.mit.edu	37	12	52639222	52639222	+	Silent	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr12:52639222C>T	uc001saa.1	+	6	1138	c.1011C>T	c.(1009-1011)gcC>gcT	p.A337A		NM_005556	NP_005547	P08729	K2C7_HUMAN	Homo sapiens keratin 7 (KRT7), mRNA.	337	Coil 2.|Rod.				cytoskeleton organization|DNA replication|interphase|interspecies interaction between organisms|regulation of translation	Golgi apparatus|keratin filament|nucleus	protein binding|structural molecule activity			endometrium(1)|kidney(1)|large_intestine(3)|lung(5)|prostate(2)|stomach(1)|urinary_tract(1)	14				BRCA - Breast invasive adenocarcinoma(357;0.105)		CCGCCATTGCCGAGGCTGAGG	0.662												
HOXC11	3227	broad.mit.edu	37	12	54367422	54367422	+	Missense_Mutation	SNP	A	A	C			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr12:54367422A>C	uc001sem.3	+	0	513	c.397A>C	c.(397-399)Acc>Ccc	p.T133P		NM_014212	NP_055027	O43248	HXC11_HUMAN	Homo sapiens homeobox C11 (HOXC11), mRNA.	133					endoderm development	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			large_intestine(1)|ovary(1)	2						CCCGCACGCAACCCCCGCCGG	0.642			T	NUP98	AML							
MYO1A	4640	broad.mit.edu	37	12	57431824	57431824	+	Missense_Mutation	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr12:57431824C>T	uc001smw.4	-	17	2030	c.1790G>A	c.(1789-1791)cGa>cAa	p.R597Q	MYO1A_uc010sqz.2_Missense_Mutation_p.R435Q|MYO1A_uc009zpd.3_Missense_Mutation_p.R597Q	NM_005379	NP_005370	Q9UBC5	MYO1A_HUMAN	Homo sapiens myosin IA (MYO1A), transcript variant 2, mRNA.	597	Myosin head-like.				sensory perception of sound|vesicle localization	brush border|cortical actin cytoskeleton|filamentous actin|lateral plasma membrane|microvillus|myosin complex	actin binding|ATP binding|calmodulin binding|motor activity			breast(1)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(12)|lung(17)|ovary(2)|skin(7)|urinary_tract(3)	50						GAACTGACCTCGCTGCTGATG	0.592												
SELPLG	6404	broad.mit.edu	37	12	109017957	109017957	+	Frame_Shift_Del	DEL	C	C	-			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr12:109017957delC	uc010sxe.2	-	1	352	c.175delG	c.(175-177)gccfs	p.A59fs	SELPLG_uc001tni.3_Frame_Shift_Del_p.A43fs|SELPLG_uc021rdm.1_Frame_Shift_Del_p.A43fs|SELPLG_uc001tnh.3_Frame_Shift_Del_p.A43fs	NM_001206609	NP_001193538	Q14242	SELPL_HUMAN	Homo sapiens selectin P ligand (SELPLG), transcript variant 1, mRNA.	43					blood coagulation|cellular response to interleukin-6	integral to plasma membrane|membrane fraction	bacterial cell surface binding|receptor binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(3)|prostate(3)|skin(1)	12						TATTCGGTGGCCTGTCTCCGG	0.582												
FOXG1	2290	broad.mit.edu	37	14	29236962	29236988	+	In_Frame_Del	DEL	GGGCGAGGGCGGCAAGGACGGGGAGGG	GGGCGAGGGCGGCAAGGACGGGGAGGG	-	rs148157138	byFrequency	TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr14:29236962_29236988delGGGCGAGGGCGGCAAGGACGGGGAGGG	uc001wqe.3	+	0	676_702	c.477_503delGGGCGAGGGCGGCAAGGACGGGGAGGG	c.(475-504)gcgggcgagggcggcaaggacggggagggg>gcg	p.GEGGKDGEG160del		NM_005249	NP_005240	P55316	FOXG1_HUMAN	Homo sapiens forkhead box G1 (FOXG1), mRNA.	160	Gly-rich.				axon midline choice point recognition|central nervous system neuron development|dorsal/ventral pattern formation|embryo development ending in birth or egg hatching|hindbrain development|inner ear morphogenesis|negative regulation of neuron differentiation|negative regulation of transcription, DNA-dependent|nonmotile primary cilium assembly|nose development|positive regulation of cell cycle|positive regulation of neuroblast proliferation|positive regulation of transcription from RNA polymerase II promoter|regulation of mitotic cell cycle|regulation of sequence-specific DNA binding transcription factor activity|tissue development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding	p.G166G(2)		breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(9)|lung(23)|ovary(2)|pancreas(1)|prostate(1)|skin(1)|urinary_tract(2)	43			LUAD - Lung adenocarcinoma(48;0.011)|Lung(238;0.0575)	GBM - Glioblastoma multiforme(265;0.00413)		agaagggggcgggcgagggcggcaaggacggggaggggggcaaggag	0.727												
KRT222	125113	broad.mit.edu	37	17	38812794	38812794	+	Nonsense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr17:38812794G>A	uc002hvc.2	-	5	813	c.748C>T	c.(748-750)Cga>Tga	p.R250*	KRT222_uc002hvb.2_Nonsense_Mutation_p.R210*	NM_152349	NP_689562	Q8N1A0	KT222_HUMAN	Homo sapiens keratin 222 (KRT222), mRNA.	250						intermediate filament	structural molecule activity			breast(1)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(3)|prostate(2)|skin(1)	15						AGATCAAATCGAAGAGAAACA	0.368												
ACPT	93650	broad.mit.edu	37	19	51295399	51295399	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr19:51295399G>A	uc002pta.1	+	4	520	c.520G>A	c.(520-522)Gag>Aag	p.E174K		NM_033068	NP_149059	Q9BZG2	PPAT_HUMAN	Homo sapiens acid phosphatase, testicular (ACPT), mRNA.	174						integral to membrane	acid phosphatase activity			central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|lung(6)|skin(3)	11		all_neural(266;0.057)		OV - Ovarian serous cystadenocarcinoma(262;0.00641)|GBM - Glioblastoma multiforme(134;0.028)		CGAGGCCGCCGAGTACCAGGA	0.706												
ZNF470	388566	broad.mit.edu	37	19	57089037	57089037	+	Nonsense_Mutation	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr19:57089037C>T	uc002qnl.4	+	5	1916	c.1240C>T	c.(1240-1242)Cag>Tag	p.Q414*	ZNF470_uc010etn.3_Intron	NM_001001668	NP_001001668	Q6ECI4	ZN470_HUMAN	Homo sapiens zinc finger protein 470 (ZNF470), mRNA.	414					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding	p.I413F(2)		endometrium(7)|large_intestine(12)|lung(11)|ovary(1)|pancreas(3)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	41		Colorectal(82;5.46e-05)|Ovarian(87;0.0822)|Renal(1328;0.157)		GBM - Glioblastoma multiforme(193;0.0294)		AGGACTTATTCAGCATAAGAG	0.413												
ZRANB3	84083	broad.mit.edu	37	2	135965224	135965224	+	Missense_Mutation	SNP	G	G	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr2:135965224G>T	uc002tum.3	-	18	2906	c.2789C>A	c.(2788-2790)tCt>tAt	p.S930Y	ZRANB3_uc002tuk.3_Missense_Mutation_p.S473Y|ZRANB3_uc002tul.3_Missense_Mutation_p.S928Y	NM_032143	NP_115519	Q5FWF4	ZRAB3_HUMAN	Homo sapiens zinc finger, RAN-binding domain containing 3 (ZRANB3), mRNA.	930						intracellular	ATP binding|DNA binding|endonuclease activity|helicase activity|zinc ion binding			NS(2)|endometrium(2)|kidney(2)|large_intestine(3)|lung(10)|upper_aerodigestive_tract(1)	20				BRCA - Breast invasive adenocarcinoma(221;0.135)		TGAATCCCAAGAGTTCGCTTT	0.428												
PRKRA	8575	broad.mit.edu	37	2	179296970	179296970	+	Missense_Mutation	SNP	C	C	T	rs148050153		TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr2:179296970C>T	uc002umf.3	-	7	997	c.796G>A	c.(796-798)Gcc>Acc	p.A266T	MIR548N_uc021vsx.1_Intron|PRKRA_uc002umc.3_Missense_Mutation_p.A98T|PRKRA_uc002umd.3_Missense_Mutation_p.A241T|PRKRA_uc002ume.3_Missense_Mutation_p.A255T|PRKRA_uc002umg.3_Missense_Mutation_p.A153T|BX538254_uc002umb.1_Intron|PRKRA_uc002umh.1_Non-coding_Transcript	NM_003690	NP_001132990	O75569	PRKRA_HUMAN	Homo sapiens protein kinase, interferon-inducible double stranded RNA dependent activator (PRKRA), transcript variant 1, mRNA.	266	DRBM 3.|Sufficient for self-association and interaction with TARBP2.				immune response|negative regulation of cell proliferation|production of siRNA involved in RNA interference|response to virus	perinuclear region of cytoplasm	double-stranded RNA binding|enzyme activator activity|protein homodimerization activity			central_nervous_system(1)|endometrium(2)|large_intestine(4)|lung(8)|ovary(1)|pancreas(1)|skin(2)	19			OV - Ovarian serous cystadenocarcinoma(117;0.00406)|Epithelial(96;0.00634)|all cancers(119;0.0265)			TGTCCATTGGCGCTCAGTTCA	0.418												
UMODL1	89766	broad.mit.edu	37	21	43519223	43519223	+	Silent	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr21:43519223G>A	uc002zag.1	+	6	1119	c.1119G>A	c.(1117-1119)ctG>ctA	p.L373L	UMODL1_uc002zad.1_Silent_p.L301L|UMODL1_uc002zae.1_Silent_p.L301L|UMODL1_uc002zaf.1_Silent_p.L373L|UMODL1_uc010gow.1_Silent_p.L165L|UMODL1_uc002zai.1_Silent_p.L24L|UMODL1_uc010gox.1_Non-coding_Transcript|UMODL1_uc010goy.1_Silent_p.L24L|UMODL1_uc002zaj.1_Non-coding_Transcript|UMODL1_uc010goz.1_Silent_p.L118L	NM_173568	NP_001186456	Q5DID0	UROL1_HUMAN	Homo sapiens uromodulin-like 1 (UMODL1), transcript variant 2, mRNA.	373	Fibronectin type-III 1.					cytoplasm|extracellular region|integral to membrane|plasma membrane	calcium ion binding|peptidase inhibitor activity			breast(2)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(5)|lung(22)|ovary(2)|prostate(3)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	47						CTGGAGTGCTGTACAGGGTGA	0.612												
ITGB2	3689	broad.mit.edu	37	21	46330269	46330269	+	Missense_Mutation	SNP	G	G	A	rs148038936	by1000genomes	TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr21:46330269G>A	uc002zgd.2	-	1	121	c.77C>T	c.(76-78)aCg>aTg	p.T26M	ITGB2_uc002zgf.3_Missense_Mutation_p.T26M|ITGB2_uc011afl.1_5'UTR|ITGB2_uc010gpw.2_Missense_Mutation_p.T26M|ITGB2_uc002zgg.2_Missense_Mutation_p.T26M	NM_001127491	NP_001120963	P05107	ITB2_HUMAN	Homo sapiens integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) (ITGB2), transcript variant 2, mRNA.	26					apoptosis|blood coagulation|cell-cell signaling|cell-matrix adhesion|inflammatory response|integrin-mediated signaling pathway|leukocyte cell-cell adhesion|multicellular organismal development|neutrophil chemotaxis|regulation of cell shape|regulation of immune response|regulation of peptidyl-tyrosine phosphorylation	integrin complex	glycoprotein binding|protein kinase binding|receptor activity	p.T26T(1)		breast(2)|central_nervous_system(3)|endometrium(2)|kidney(1)|large_intestine(6)|lung(14)|ovary(4)|skin(3)	35				Colorectal(79;0.0669)	Simvastatin(DB00641)	CTTGAACTTCGTGCACTCCTG	0.657												
SLC35E4	339665	broad.mit.edu	37	22	31042730	31042730	+	Missense_Mutation	SNP	G	G	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr22:31042730G>T	uc003ais.1	+	1	1410	c.765G>T	c.(763-765)tgG>tgT	p.W255C	SLC35E4_uc003ait.3_Intron	NM_001001479	NP_001001479	Q6ICL7	S35E4_HUMAN	Homo sapiens solute carrier family 35, member E4 (SLC35E4), mRNA.	255	Leu-rich.					integral to membrane				autonomic_ganglia(1)|endometrium(1)|large_intestine(2)|lung(3)|ovary(1)|pancreas(1)|skin(1)	10						CTCGCCTCTGGGCCTGCATCC	0.677												
RAD54L2	23132	broad.mit.edu	37	3	51690054	51690054	+	Missense_Mutation	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr3:51690054C>T	uc011bdt.2	+	18	3219	c.3094C>T	c.(3094-3096)Ccc>Tcc	p.P1032S	RAD54L2_uc003dbh.3_Missense_Mutation_p.P621S|RAD54L2_uc011bdu.2_Missense_Mutation_p.P726S|RAD54L2_uc003dbj.3_Missense_Mutation_p.P358S	NM_015106	NP_055921	Q9Y4B4	ARIP4_HUMAN	Homo sapiens RAD54-like 2 (S. cerevisiae) (RAD54L2), mRNA.	1032						nucleus	ATP binding|DNA binding|helicase activity			NS(2)|breast(1)|cervix(2)|endometrium(4)|large_intestine(5)|liver(2)|lung(9)|ovary(4)|skin(2)	31				BRCA - Breast invasive adenocarcinoma(193;0.000102)|Kidney(197;0.000758)|KIRC - Kidney renal clear cell carcinoma(197;0.000896)		CACCCCCATCCCCATGATGCC	0.522												
RAP2B	5912	broad.mit.edu	37	3	152880771	152880771	+	Missense_Mutation	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr3:152880771C>T	uc003ezr.3	+	0	743	c.289C>T	c.(289-291)Cgg>Tgg	p.R97W		NM_002886	NP_002877	P61225	RAP2B_HUMAN	Homo sapiens RAP2B, member of RAS oncogene family (RAP2B), mRNA.	97					Rap protein signal transduction|regulation of protein tyrosine kinase activity	recycling endosome membrane	GTP binding|GTPase activity			NS(1)|kidney(1)|large_intestine(1)|lung(3)|prostate(1)	7			LUSC - Lung squamous cell carcinoma(72;0.0628)|Lung(72;0.11)			CAAGCCCATGCGGGACCAGAT	0.617												
NLGN1	22871	broad.mit.edu	37	3	173998531	173998531	+	Missense_Mutation	SNP	G	G	C			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr3:173998531G>C	uc021xhm.1	+	6	2350	c.2030G>C	c.(2029-2031)aGa>aCa	p.R677T	NLGN1_uc003fio.1_Missense_Mutation_p.R637T|NLGN1_uc003fip.1_Missense_Mutation_p.R637T	NM_014932	NP_055747	Q8N2Q7	NLGN1_HUMAN	Homo sapiens neuroligin 1 (NLGN1), mRNA.	654					calcium-dependent cell-cell adhesion|neuron cell-cell adhesion|neuronal signal transduction|positive regulation of dendritic spine development|positive regulation of excitatory postsynaptic membrane potential|positive regulation of intracellular protein kinase cascade|positive regulation of synaptogenesis|protein targeting|regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|regulation of N-methyl-D-aspartate selective glutamate receptor activity|synapse assembly|synaptic vesicle targeting	cell junction|cell surface|dendrite|integral to plasma membrane|postsynaptic density|postsynaptic membrane	cell adhesion molecule binding|neurexin binding|receptor activity			breast(2)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(9)|liver(2)|lung(54)|ovary(1)|pancreas(1)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	83	Ovarian(172;0.0025)		LUSC - Lung squamous cell carcinoma(14;5.36e-13)|Lung(28;9.49e-13)			ATCACTTTCAGACCTACGAGA	0.433												
ALB	213	broad.mit.edu	37	4	74274453	74274453	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr4:74274453G>A	uc003hgs.4	+	3	486	c.413G>A	c.(412-414)cGa>cAa	p.R138Q	ALB_uc011cbe.2_Intron|ALB_uc003hgw.4_Intron|ALB_uc011cbf.2_Missense_Mutation_p.R28Q	NM_000477	NP_000468	P02768	ALBU_HUMAN	Homo sapiens albumin (ALB), mRNA.	138	Albumin 1.		R -> G (in Yanomama-2).		bile acid and bile salt transport|bile acid metabolic process|cellular response to starvation|hemolysis by symbiont of host erythrocytes|lipoprotein metabolic process|maintenance of mitochondrion location|negative regulation of apoptosis|platelet activation|platelet degranulation|sodium-independent organic anion transport|transmembrane transport	extracellular space|platelet alpha granule lumen|protein complex	antioxidant activity|chaperone binding|copper ion binding|DNA binding|drug binding|fatty acid binding|pyridoxal phosphate binding|toxin binding			NS(1)|endometrium(4)|kidney(1)|large_intestine(6)|liver(9)|lung(16)|ovary(3)|prostate(2)|skin(4)|stomach(1)|urinary_tract(1)	48	Breast(15;0.00102)		Epithelial(6;4.8e-05)|OV - Ovarian serous cystadenocarcinoma(6;0.000263)|all cancers(17;0.000472)|Lung(101;0.103)|LUSC - Lung squamous cell carcinoma(112;0.154)		Acenocoumarol(DB01418)|Acitretin(DB00459)|Alfentanil(DB00802)|Aluminium(DB01370)|Auranofin(DB00995)|Bismuth(DB01402)|Captopril(DB01197)|Carboplatin(DB00958)|Cefalotin(DB00456)|Cefazolin(DB01327)|Cefonicid(DB01328)|Cefoperazone(DB01329)|Chlorpheniramine(DB01114)|Chlorpromazine(DB00477)|Ciprofloxacin(DB00537)|Clonazepam(DB01068)|Cloxacillin(DB01147)|Cytarabine(DB00987)|Dantrolene(DB01219)|Diclofenac(DB00586)|Diflunisal(DB00861)|Digitoxin(DB01396)|Estrone(DB00655)|Ethacrynic acid(DB00903)|Etodolac(DB00749)|Flurbiprofen(DB00712)|Gadobenate Dimeglumine(DB00743)|Gatifloxacin(DB01044)|Gliclazide(DB01120)|Halothane(DB01159)|Human Serum Albumin(DB00062)|Hyaluronidase(DB00070)|Ibuprofen(DB01050)|Insulin-detemir(DB01307)|Insulin-glargine(DB01308)|Iodipamide(DB04711)|Ketoprofen(DB01009)|Levamisole(DB00848)|Levothyroxine(DB00451)|Liothyronine(DB00279)|Mefenamic acid(DB00784)|Mephenytoin(DB00532)|Methotrexate(DB00563)|Nortriptyline(DB00540)|Oxazepam(DB00842)|Paclitaxel(DB01229)|Phenprocoumon(DB00946)|Probenecid(DB01032)|Propofol(DB00818)|Pyridoxine(DB00165)|Salicyclic acid(DB00936)|Saquinavir(DB01232)|Serum albumin iodonated(DB00064)|Serum albumin(DB00096)|Sodium lauryl sulfate(DB00815)|Sucralfate(DB00364)|Sulfamethizole(DB00576)|Sulindac(DB00605)|Suprofen(DB00870)|Testosterone(DB00624)|Xanthophyll(DB00137)	AACCTCCCCCGATTGGTGAGA	0.398												
PCDHB5	26167	broad.mit.edu	37	5	140516934	140516934	+	Missense_Mutation	SNP	G	G	A			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr5:140516934G>A	uc003liq.3	+	0	2135	c.1918G>A	c.(1918-1920)Gtg>Atg	p.V640M		NM_015669	NP_056484	Q9Y5E4	PCDB5_HUMAN	Homo sapiens protocadherin beta 5 (PCDHB5), mRNA.	640	Cadherin 6.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding|protein binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(12)|kidney(1)|large_intestine(18)|lung(25)|ovary(3)|prostate(6)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(2)	81			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GCACAGGCTGGTGGTGCTGGT	0.706												
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr7:140453136A>T	uc003vwc.4	-	14	1860	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333	NP_004324	P15056	BRAF_HUMAN	Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA.	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome			
NFIB	4781	broad.mit.edu	37	9	14150145	14150145	+	Missense_Mutation	SNP	T	T	C			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr9:14150145T>C	uc022bdo.1	-	5	1341	c.806_splice	c.e5+1	p.S269_splice	NFIB_uc003zld.3_Splice_Site_p.S17_splice|NFIB_uc003zlf.3_Splice_Site_p.S269_splice|NFIB_uc003zle.3_Splice_Site_p.S269_splice|NFIB_uc022bdp.1_Splice_Site_p.S295_splice|NFIB_uc011lmo.2_Splice_Site_p.S269_splice	NM_001190737	NP_001177666	O00712	NFIB_HUMAN	Homo sapiens nuclear factor I/B (NFIB), transcript variant 1, mRNA.	269					anterior commissure morphogenesis|chondrocyte differentiation|Clara cell differentiation|commissural neuron axon guidance|DNA replication|glial cell differentiation|lung ciliated cell differentiation|negative regulation of DNA binding|negative regulation of epithelial cell proliferation involved in lung morphogenesis|negative regulation of mesenchymal cell proliferation involved in lung development|positive regulation of transcription from RNA polymerase II promoter|principal sensory nucleus of trigeminal nerve development|Type I pneumocyte differentiation|Type II pneumocyte differentiation	cerebellar mossy fiber|nucleolus|nucleus	RNA polymerase II transcription corepressor activity|sequence-specific DNA binding RNA polymerase II transcription factor activity			central_nervous_system(2)|endometrium(2)|large_intestine(7)|lung(5)|skin(1)	17				GBM - Glioblastoma multiforme(50;4.4e-08)|LUAD - Lung adenocarcinoma(58;0.119)|Lung(218;0.164)		TTTCAGTACCTGCTTGGTGGA	0.458			T	"""MYB, HGMA2"""	"""adenoid cystic carcinoma, lipoma"""							
FAM75D1	389763	broad.mit.edu	37	9	84609194	84609194	+	Missense_Mutation	SNP	A	A	G			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr9:84609194A>G	uc004amn.3	+	3	3856	c.3809A>G	c.(3808-3810)cAg>cGg	p.Q1270R		NM_001001670	NP_001001670	Q6ZQQ2	F75D1_HUMAN	Homo sapiens family with sequence similarity 75, member D1 (FAM75D1), mRNA.	1270						integral to membrane				cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|lung(57)|prostate(3)|skin(3)|stomach(1)|urinary_tract(1)	88						GCACAGAAGCAGGAGCCCAGG	0.537												
TNC	3371	broad.mit.edu	37	9	117844148	117844148	+	Silent	SNP	C	C	T			TCGA-06-0151-01A-01D-1491-08	TCGA-06-0151-10A-01D-1491-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5fea9ebc-8c1b-4078-af87-79c7f5b5470b	5d8879d4-295c-4a2a-a3fb-d402e2f1f8f5	g.chr9:117844148C>T	uc004bjj.4	-	5	2719	c.2307G>A	c.(2305-2307)cgG>cgA	p.R769R	TNC_uc010mvf.3_Silent_p.R769R|TNC_uc022bmj.1_Silent_p.R769R	NM_002160	NP_002151	P24821	TENA_HUMAN	Homo sapiens tenascin C (TNC), mRNA.	769	Fibronectin type-III 2.				cell adhesion|response to wounding|signal transduction	extracellular space	receptor binding|syndecan binding			NS(3)|breast(5)|central_nervous_system(4)|endometrium(8)|kidney(6)|large_intestine(32)|liver(1)|lung(39)|ovary(1)|pancreas(2)|prostate(5)|skin(5)|stomach(5)|upper_aerodigestive_tract(2)|urinary_tract(2)	120						GACCAGTTTGCCGGTAAGAGG	0.522												
