Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values
EXOSC10	5394	broad.mit.edu	37	1	11151619	11151619	+	Missense_Mutation	SNP	C	C	G	rs146190133		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:11151619C>G	uc001asa.3	-	3	458	c.408G>C	c.(406-408)aaG>aaC	p.K136N	EXOSC10_uc001asb.3_Missense_Mutation_p.K136N|EXOSC10_uc009vmy.1_Missense_Mutation_p.K136N	NM_001001998	NP_001001998	Q01780	EXOSX_HUMAN	Homo sapiens exosome component 10 (EXOSC10), transcript variant 1, mRNA.	136					CUT catabolic process|histone mRNA catabolic process|maturation of 5.8S rRNA|nuclear polyadenylation-dependent rRNA catabolic process|nuclear retention of unspliced pre-mRNA at the site of transcription|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	cytoplasm|nuclear exosome (RNase complex)|nucleolus|transcriptionally active chromatin	3'-5' exonuclease activity|exoribonuclease activity|identical protein binding|nucleotide binding|protein serine/threonine kinase activity|RNA binding			central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(9)|prostate(1)|stomach(3)|upper_aerodigestive_tract(1)	27	Ovarian(185;0.249)	Lung NSC(185;1.74e-05)|all_lung(284;2.05e-05)|Renal(390;0.000147)|Colorectal(325;0.00205)|Breast(348;0.00262)|Hepatocellular(190;0.00913)|Ovarian(437;0.00965)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;4.18e-07)|COAD - Colon adenocarcinoma(227;8.33e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000315)|Kidney(185;0.000832)|KIRC - Kidney renal clear cell carcinoma(229;0.00269)|READ - Rectum adenocarcinoma(331;0.0526)|STAD - Stomach adenocarcinoma(313;0.202)		GCTGTTGATTCTTGTTTACAC	0.458												
UBIAD1	29914	broad.mit.edu	37	1	11334002	11334002	+	Silent	SNP	C	C	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:11334002C>G	uc001asg.3	+	0	748	c.414C>G	c.(412-414)ctC>ctG	p.L138L		NM_013319	NP_037451	Q9Y5Z9	UBIA1_HUMAN	Homo sapiens UbiA prenyltransferase domain containing 1 (UBIAD1), mRNA.	138					menaquinone biosynthetic process	endoplasmic reticulum membrane|integral to membrane|mitochondrion|nucleus	prenyltransferase activity			endometrium(1)|kidney(2)|large_intestine(2)|lung(4)|prostate(3)	12	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.000818)|all_lung(284;0.00105)|Colorectal(325;0.0062)|Breast(348;0.012)|Hepatocellular(190;0.0305)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;1.52e-06)|COAD - Colon adenocarcinoma(227;0.000254)|BRCA - Breast invasive adenocarcinoma(304;0.000299)|Kidney(185;0.000754)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.00727)|READ - Rectum adenocarcinoma(331;0.0487)		GAGTCTTCCTCTACACGTTGG	0.537												
TRIM62	55223	broad.mit.edu	37	1	33646782	33646782	+	Silent	SNP	G	G	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:33646782G>C	uc001bxb.3	-	0	890	c.252C>G	c.(250-252)ctC>ctG	p.L84L		NM_018207	NP_060677	Q9BVG3	TRI62_HUMAN	Homo sapiens tripartite motif containing 62 (TRIM62), mRNA.	84						intracellular	zinc ion binding			endometrium(3)|kidney(2)|large_intestine(4)|lung(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	15		Myeloproliferative disorder(586;0.0393)				GGCGCGCGTTGAGGATGGCGT	0.701												
TCHH	7062	broad.mit.edu	37	1	152080828	152080828	+	Missense_Mutation	SNP	C	C	T	rs71585886		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:152080828C>T	uc009wne.1	-	2	5137	c.4865G>A	c.(4864-4866)cGc>cAc	p.R1622H	TCHH_uc001ezp.2_Missense_Mutation_p.R1622H	NM_007113	NP_009044	Q07283	TRHY_HUMAN	Homo sapiens trichohyalin (TCHH), mRNA.	1622	23 X 26 AA approximate tandem repeats.				keratinization	cytoskeleton	calcium ion binding			NS(2)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(20)|kidney(9)|large_intestine(16)|lung(33)|ovary(3)|pancreas(1)|prostate(4)|skin(5)|upper_aerodigestive_tract(2)|urinary_tract(4)	105	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			TTCGTCTTCGCGGAATTTTCT	0.602												
OR10J3	441911	broad.mit.edu	37	1	159283794	159283794	+	Missense_Mutation	SNP	T	T	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:159283794T>A	uc010piu.2	-	0	656	c.656A>T	c.(655-657)tAt>tTt	p.Y219F		NM_001004467	NP_001004467	Q5JRS4	O10J3_HUMAN	Homo sapiens olfactory receptor, family 10, subfamily J, member 3 (OR10J3), mRNA.	219					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)|endometrium(7)|kidney(4)|large_intestine(7)|lung(19)|ovary(3)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	47	all_hematologic(112;0.0429)					GATGAGGACATAGGAGATAAA	0.502												
SLAMF6	114836	broad.mit.edu	37	1	160456502	160456502	+	Missense_Mutation	SNP	C	C	T	rs151001421		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:160456502C>T	uc001fwe.2	-	7	1064	c.994G>A	c.(994-996)Gtg>Atg	p.V332M	SLAMF6_uc010pji.2_Missense_Mutation_p.V221M|SLAMF6_uc001fwd.2_Missense_Mutation_p.V331M|SLAMF6_uc010pjh.2_Missense_Mutation_p.V282M	NM_001184714	NP_001171643	Q96DU3	SLAF6_HUMAN	Homo sapiens SLAM family member 6 (SLAMF6), transcript variant 1, mRNA.	332						integral to membrane|plasma membrane	receptor activity			NS(1)|breast(1)|central_nervous_system(1)|endometrium(1)|large_intestine(4)|lung(8)|ovary(1)|pancreas(1)|skin(4)	22	all_cancers(52;1.05e-18)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.0923)			GCAACTTACACGACATTGTCA	0.483												
KLHDC8A	55220	broad.mit.edu	37	1	205312607	205312607	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:205312607G>A	uc001hcf.1	-	1	694	c.126C>T	c.(124-126)aaC>aaT	p.N42N	KLHDC8A_uc010prg.1_Intron|KLHDC8A_uc001hcg.1_Silent_p.N42N	NM_018203	NP_060673	Q8IYD2	KLD8A_HUMAN	Homo sapiens kelch domain containing 8A (KLHDC8A), mRNA.	42								p.D41H(1)		breast(1)|endometrium(3)|large_intestine(1)|lung(4)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	14	Breast(84;0.23)		BRCA - Breast invasive adenocarcinoma(75;0.117)			TGGGGACGCCGTTGTCGTCAC	0.716												
RAB3GAP2	25782	broad.mit.edu	37	1	220340949	220340949	+	Missense_Mutation	SNP	C	C	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:220340949C>A	uc010puk.1	-	24	3039	c.2875G>T	c.(2875-2877)Gct>Tct	p.A959S	RAB3GAP2_uc021pjf.1_Missense_Mutation_p.A959S|RAB3GAP2_uc001hmf.2_Non-coding_Transcript|RAB3GAP2_uc001hmg.2_Missense_Mutation_p.A539S	NM_012414	NP_036546	Q9H2M9	RBGPR_HUMAN	Homo sapiens RAB3 GTPase activating protein subunit 2 (non-catalytic) (RAB3GAP2), mRNA.	959					intracellular protein transport	cytoplasm|soluble fraction	GTPase activator activity|protein heterodimerization activity			breast(1)|central_nervous_system(1)|endometrium(6)|kidney(2)|large_intestine(8)|lung(13)|ovary(1)|pancreas(1)|prostate(4)|skin(1)|urinary_tract(1)	39				GBM - Glioblastoma multiforme(131;0.0443)		TCTTCATTAGCCAGTTTTAAT	0.398												
HHIPL2	79802	broad.mit.edu	37	1	222717502	222717502	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:222717502G>A	uc001hnh.1	-	1	409	c.351C>T	c.(349-351)taC>taT	p.Y117Y		NM_024746	NP_079022	Q6UWX4	HIPL2_HUMAN	Homo sapiens HHIP-like 2 (HHIPL2), mRNA.	117					carbohydrate metabolic process	extracellular region	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor|quinone binding			NS(2)|endometrium(8)|kidney(4)|large_intestine(7)|lung(28)|ovary(1)|prostate(3)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	59				GBM - Glioblastoma multiforme(131;0.0185)		TTTCGGCGTCGTAGAGGTGGG	0.567												
NUP133	55746	broad.mit.edu	37	1	229606471	229606471	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr1:229606471G>A	uc001htn.3	-	14	2024	c.1932C>T	c.(1930-1932)gcC>gcT	p.A644A		NM_018230	NP_060700	Q8WUM0	NU133_HUMAN	Homo sapiens nucleoporin 133kDa (NUP133), mRNA.	644					carbohydrate metabolic process|glucose transport|mitotic prometaphase|mRNA export from nucleus|nuclear pore organization|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	condensed chromosome kinetochore|cytosol|Nup107-160 complex	nucleocytoplasmic transporter activity|protein binding			NS(1)|breast(7)|endometrium(1)|kidney(6)|large_intestine(9)|lung(20)|ovary(1)|pancreas(1)|prostate(3)|skin(3)|stomach(4)	56	Breast(184;0.104)|Ovarian(103;0.249)	Prostate(94;0.167)				ACAGCTTTTCGGCATGCTCAC	0.493												
ARHGAP22	58504	broad.mit.edu	37	10	49667897	49667897	+	Silent	SNP	G	G	A	rs78086414		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr10:49667897G>A	uc001jgu.3	-	4	834	c.537C>T	c.(535-537)caC>caT	p.H179H	ARHGAP22_uc001jgs.3_Silent_p.H73H|ARHGAP22_uc001jgt.3_Silent_p.H163H|ARHGAP22_uc010qgl.2_Silent_p.H120H|ARHGAP22_uc010qgm.2_Silent_p.H169H|ARHGAP22_uc001jgv.3_5'UTR	NM_021226	NP_067049	Q7Z5H3	RHG22_HUMAN	Homo sapiens Rho GTPase activating protein 22 (ARHGAP22), transcript variant 3, mRNA.	163	Rho-GAP.				angiogenesis|cell differentiation|regulation of small GTPase mediated signal transduction|regulation of transcription, DNA-dependent|small GTPase mediated signal transduction|transcription, DNA-dependent	cytosol|nucleus	GTPase activator activity			endometrium(3)|large_intestine(3)|lung(7)|ovary(1)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	18						ACTTCCGCTCGTGGTGGACTG	0.642												
TLL2	7093	broad.mit.edu	37	10	98156950	98156950	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr10:98156950C>T	uc001kml.2	-	10	1618	c.1377G>A	c.(1375-1377)gcG>gcA	p.A459A	TLL2_uc009xvf.2_Silent_p.A437A	NM_012465	NP_036597	Q9Y6L7	TLL2_HUMAN	Homo sapiens tolloid-like 2 (TLL2), mRNA.	459	CUB 1.				cell differentiation|multicellular organismal development|proteolysis	extracellular region	calcium ion binding|metalloendopeptidase activity|zinc ion binding	p.A459A(2)		NS(1)|breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(3)|kidney(5)|large_intestine(15)|lung(22)|ovary(1)|pancreas(1)|prostate(1)|skin(3)	58		Colorectal(252;0.0846)		Epithelial(162;1.51e-07)|all cancers(201;7.59e-06)		AACCTTCGTACGCTGCAAAGA	0.622												
OR4D10	390197	broad.mit.edu	37	11	59244963	59244963	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr11:59244963C>T	uc001nnz.1	+	0	61	c.61C>T	c.(61-63)Cgg>Tgg	p.R21W		NM_001004705	NP_001004705	Q8NGI6	OR4DA_HUMAN	Homo sapiens olfactory receptor, family 4, subfamily D, member 10 (OR4D10), mRNA.	21					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|breast(2)|endometrium(2)|kidney(2)|large_intestine(4)|lung(12)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	30						GACCCAGAATCGGGAAGTGAG	0.413												
PKNOX2	63876	broad.mit.edu	37	11	125255470	125255470	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr11:125255470C>T	uc001qbu.3	+	5	565	c.251C>T	c.(250-252)aCg>aTg	p.T84M	PKNOX2_uc010saz.2_Missense_Mutation_p.T55M|PKNOX2_uc010sba.2_Missense_Mutation_p.T55M|PKNOX2_uc010sbb.2_Missense_Mutation_p.T20M	NM_022062	NP_071345	Q96KN3	PKNX2_HUMAN	Homo sapiens PBX/knotted 1 homeobox 2 (PKNOX2), mRNA.	84						nucleus	sequence-specific DNA binding transcription factor activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(4)|lung(14)|ovary(3)|upper_aerodigestive_tract(3)|urinary_tract(2)	29		Breast(109;0.00234)|all_lung(97;0.0191)|Lung NSC(97;0.0196)|Medulloblastoma(222;0.0447)|all_neural(223;0.116)		BRCA - Breast invasive adenocarcinoma(274;5.1e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.117)		CCGCTCCTGACGCTGCTGTTT	0.567												
DDX11L11	100887824	broad.mit.edu	37	12	92920	92920	+	Missense_Mutation	SNP	C	C	G	rs145563795	by1000genomes	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr12:92920C>G	uc010sdi.1	-	0	99	c.71G>C	c.(70-72)aGt>aCt	p.S24T	DDX11L11_uc010sdj.1_Non-coding_Transcript					SubName: Full=DEAD/H box polypeptide 11 like 11;																		ACTCACAAGACTGTGATCCAA	0.622												
LTBR	4055	broad.mit.edu	37	12	6497971	6497971	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr12:6497971C>T	uc001qny.1	+	7	949	c.781C>T	c.(781-783)Ctg>Ttg	p.L261L	LTBR_uc010sfc.1_Silent_p.L242L|LTBR_uc001qnz.1_Silent_p.L256L	NM_002342	NP_002333	P36941	TNR3_HUMAN	Homo sapiens lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR), mRNA.	261					apoptosis|cellular response to mechanical stimulus|interspecies interaction between organisms|positive regulation of I-kappaB kinase/NF-kappaB cascade	integral to membrane	protein binding|receptor activity			breast(1)|cervix(1)|kidney(2)|large_intestine(4)|lung(4)|ovary(1)|prostate(2)	15						TGCAGGATCGCTGCTCAAGAG	0.562												
NAB2	4665	broad.mit.edu	37	12	57485446	57485446	+	Missense_Mutation	SNP	T	T	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr12:57485446T>C	uc001smz.3	+	1	1000	c.622T>C	c.(622-624)Ttc>Ctc	p.F208L		NM_005967	NP_005958	Q15742	NAB2_HUMAN	Homo sapiens NGFI-A binding protein 2 (EGR1 binding protein 2) (NAB2), mRNA.	208					cell proliferation|negative regulation of transcription from RNA polymerase III promoter|transcription, DNA-dependent	nucleus	transcription corepressor activity	p.F208L(2)		breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(6)|lung(5)|ovary(1)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	20						CTCGCCCCCCTTCTCCCCCCC	0.716												
SLC17A8	246213	broad.mit.edu	37	12	100811900	100811900	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr12:100811900G>A	uc010svi.2	+	10	1704	c.1391G>A	c.(1390-1392)tGt>tAt	p.C464Y	SLC17A8_uc009ztx.3_Missense_Mutation_p.C414Y	NM_139319	NP_647480	Q8NDX2	VGLU3_HUMAN	Homo sapiens solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 (SLC17A8), transcript variant 1, mRNA.	464					neurotransmitter transport|sensory perception of sound|sodium ion transport	cell junction|integral to membrane|synaptic vesicle membrane|synaptosome	L-glutamate transmembrane transporter activity|symporter activity	p.C464S(1)		NS(1)|endometrium(2)|kidney(1)|large_intestine(6)|lung(25)|ovary(3)|pancreas(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	44						GGAATGGTCTGTCCCCTCATT	0.498												
SIAH3	283514	broad.mit.edu	37	13	46358034	46358034	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr13:46358034G>A	uc001vap.3	-	1	376	c.294C>T	c.(292-294)caC>caT	p.H98H		NM_198849	NP_942146	Q8IW03	SIAH3_HUMAN	Homo sapiens seven in absentia homolog 3 (Drosophila) (SIAH3), mRNA.	98	His-rich.				multicellular organismal development|ubiquitin-dependent protein catabolic process	nucleus	metal ion binding			large_intestine(3)|lung(7)|ovary(1)|skin(1)	12						CCGGGTTGGCGTGCAGCCCCG	0.682												
NRXN3	9369	broad.mit.edu	37	14	80328137	80328137	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr14:80328137G>A	uc001xun.3	+	16	3507	c.3016G>A	c.(3016-3018)Gcc>Acc	p.A1006T	NRXN3_uc001xum.1_Non-coding_Transcript|NRXN3_uc001xup.2_Non-coding_Transcript|NRXN3_uc001xuq.2_Missense_Mutation_p.A582T|NRXN3_uc010asw.3_Missense_Mutation_p.A404T|NRXN3_uc001xur.4_Missense_Mutation_p.A377T	NM_004796	NP_004787	Q9HDB5	NRX3B_HUMAN	Homo sapiens neurexin 3 (NRXN3), transcript variant 1, mRNA.	582					angiogenesis|cell adhesion	integral to membrane		p.Y1005Y(2)		NS(1)|breast(4)|central_nervous_system(1)|endometrium(6)|kidney(2)|large_intestine(23)|lung(40)|ovary(3)|pancreas(2)|prostate(5)|skin(7)|upper_aerodigestive_tract(9)|urinary_tract(1)	104		Renal(4;0.00876)		BRCA - Breast invasive adenocarcinoma(234;0.00544)|Kidney(3;0.029)|KIRC - Kidney renal clear cell carcinoma(182;0.223)		CCTCCTGTACGCCATGTACAA	0.597												
DIO3	1735	broad.mit.edu	37	14	102028607	102028607	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr14:102028607C>T	uc021sdx.1	+	0	920	c.774C>T	c.(772-774)ttC>ttT	p.F258F	DIO3AS_uc001ykd.1_5'Flank|DIO3OS_uc001yke.3_5'Flank|DIO3AS_uc001ykf.3_5'Flank|DIO3AS_uc001ykg.3_5'Flank|DIO3AS_uc001ykh.3_5'Flank|DIO3AS_uc021sdw.1_5'Flank	NM_001362	NP_001353	P55073	IOD3_HUMAN	Homo sapiens deiodinase, iodothyronine, type III (DIO3), mRNA.	232					cellular nitrogen compound metabolic process|hormone biosynthetic process	endosome membrane|integral to membrane|plasma membrane	thyroxine 5'-deiodinase activity|thyroxine 5-deiodinase activity			central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(4)|lung(8)|ovary(3)|skin(1)	22		all_neural(303;0.185)				GCGCCTACTTCGAGCGTCTCT	0.632												
GOLGA6L6	727832	broad.mit.edu	37	15	20743796	20743796	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr15:20743796C>T	uc001ytk.2	-	3	499	c.408G>A	c.(406-408)acG>acA	p.T136T	DQ595648_uc021sey.1_5'Flank	NM_001145004	NP_001138476	A8MZA4	GG6L6_HUMAN	Homo sapiens golgin A6 family-like 6 (GOLGA6L6), mRNA.	136								p.T136T(2)		NS(3)|endometrium(4)|kidney(1)|skin(3)	11						TTTTCTGACACGTAAGGATTC	0.493												
CEP152	22995	broad.mit.edu	37	15	49076318	49076318	+	Splice_Site	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr15:49076318C>T	uc001zwz.3	-	10	1367	c.1174_splice	c.e10-1	p.E392_splice	CEP152_uc001zwy.3_Splice_Site_p.E392_splice|CEP152_uc001zxa.2_Splice_Site_p.E299_splice	NM_001194998	NP_001181927	O94986	CE152_HUMAN	Homo sapiens centrosomal protein 152kDa (CEP152), transcript variant 1, mRNA.	392					centrosome duplication|G2/M transition of mitotic cell cycle	centrosome|cytosol	protein kinase binding			breast(3)|cervix(3)|endometrium(3)|kidney(3)|large_intestine(16)|lung(30)|ovary(1)|prostate(2)|skin(2)	63		all_lung(180;0.0428)		all cancers(107;1.08e-07)|GBM - Glioblastoma multiforme(94;2.32e-06)		AAATGTCTTCCTAAATAGAAA	0.294												
SMG1	23049	broad.mit.edu	37	16	18853724	18853724	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr16:18853724C>T	uc002dfm.3	-	39	6635	c.6272G>A	c.(6271-6273)cGt>cAt	p.R2091H	SMG1_uc010bwb.3_Missense_Mutation_p.R1951H|SMG1_uc010bwa.3_Missense_Mutation_p.R822H|SMG1_uc021ted.1_Missense_Mutation_p.R389H	NM_015092	NP_055907	Q96Q15	SMG1_HUMAN	Homo sapiens smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) (SMG1), mRNA.	2091					DNA repair|mRNA export from nucleus|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|peptidyl-serine phosphorylation|phosphatidylinositol phosphorylation|protein autophosphorylation	cytoplasm|nucleus	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity			NS(2)|breast(8)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(16)|lung(37)|ovary(1)|skin(1)|stomach(4)|urinary_tract(1)	92						TTCTTCAAGACGCAAGATGTA	0.408												
FAM83G	644815	broad.mit.edu	37	17	18875008	18875008	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr17:18875008G>A	uc002guw.3	-	5	2303	c.2136C>T	c.(2134-2136)gaC>gaT	p.D712D	SLC5A10_uc002gur.1_Intron|SLC5A10_uc002guu.1_Intron|SLC5A10_uc002gut.1_Intron|SLC5A10_uc002guv.1_Intron|SLC5A10_uc010vyl.1_Intron	NM_001039999	NP_001035088	A6ND36	FA83G_HUMAN	Homo sapiens family with sequence similarity 83, member G (FAM83G), mRNA.	712										central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(3)|lung(7)|ovary(2)|prostate(3)|stomach(1)	22						CTGGGAAGCCGTCTTTATCCC	0.622												
KCNJ18	3768	broad.mit.edu	37	17	21319359	21319359	+	Silent	SNP	G	G	A	rs147653221	byFrequency	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr17:21319359G>A	uc021tss.1	+	2	1075	c.705G>A	c.(703-705)ccG>ccA	p.P235P	KCNJ18_uc002gyv.1_Silent_p.P235P|KCNJ18_uc021tst.1_Silent_p.P235P	NM_001194958	NP_001181887	B7U540	IRK18_HUMAN	Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 18 (KCNJ18), mRNA.	235						integral to membrane	inward rectifier potassium channel activity										TCATCAAGCCGCGGGTCACCG	0.632												
CNTNAP1	8506	broad.mit.edu	37	17	40843451	40843451	+	Missense_Mutation	SNP	C	C	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr17:40843451C>A	uc002iay.3	+	14	2482	c.2266C>A	c.(2266-2268)Cag>Aag	p.Q756K	CNTNAP1_uc010wgs.2_Non-coding_Transcript	NM_003632	NP_003623	P78357	CNTP1_HUMAN	Homo sapiens contactin associated protein 1 (CNTNAP1), mRNA.	756	Fibrinogen C-terminal.				axon guidance|cell adhesion	paranode region of axon	receptor activity|receptor binding|SH3 domain binding|SH3/SH2 adaptor activity			NS(1)|breast(4)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(11)|lung(15)|ovary(5)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	49		Breast(137;0.000143)		BRCA - Breast invasive adenocarcinoma(366;0.143)		GCCTGTCACTCAGGTAGTGAT	0.587												
METRNL	284207	broad.mit.edu	37	17	81042908	81042908	+	Missense_Mutation	SNP	C	C	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr17:81042908C>A	uc002kgh.3	+	1	390	c.265C>A	c.(265-267)Ctc>Atc	p.L89I	METRNL_uc002kgi.3_Missense_Mutation_p.L7I	NM_001004431	NP_001004431	Q641Q3	METRL_HUMAN	Homo sapiens meteorin, glial cell differentiation regulator-like (METRNL), mRNA.	89						extracellular region				endometrium(1)|kidney(1)|large_intestine(1)|lung(3)|skin(1)|upper_aerodigestive_tract(1)	8	Breast(20;0.000443)|all_neural(118;0.0779)		BRCA - Breast invasive adenocarcinoma(99;0.0517)|OV - Ovarian serous cystadenocarcinoma(97;0.0868)			AACAGGTGCTCTCATCGTTAA	0.617												
METRNL	284207	broad.mit.edu	37	17	81042984	81042984	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr17:81042984C>T	uc002kgh.3	+	1	466	c.341C>T	c.(340-342)tCc>tTc	p.S114F	METRNL_uc002kgi.3_Missense_Mutation_p.S32F	NM_001004431	NP_001004431	Q641Q3	METRL_HUMAN	Homo sapiens meteorin, glial cell differentiation regulator-like (METRNL), mRNA.	114						extracellular region				endometrium(1)|kidney(1)|large_intestine(1)|lung(3)|skin(1)|upper_aerodigestive_tract(1)	8	Breast(20;0.000443)|all_neural(118;0.0779)		BRCA - Breast invasive adenocarcinoma(99;0.0517)|OV - Ovarian serous cystadenocarcinoma(97;0.0868)			TTCACGGACTCCTCGGGGGCC	0.592												
MUC16	94025	broad.mit.edu	37	19	9026244	9026244	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:9026244G>A	uc002mkp.3	-	13	36946	c.36742C>T	c.(36742-36744)Cgt>Tgt	p.R12248C		NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	Homo sapiens mucin 16, cell surface associated (MUC16), mRNA.	12250	SEA 2.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						CCAGTGCGACGCATGTCCTCC	0.542												
MUC16	94025	broad.mit.edu	37	19	9085463	9085463	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:9085463C>T	uc002mkp.3	-	0	6556	c.6352G>A	c.(6352-6354)Gcg>Acg	p.A2118T		NM_024690	NP_078966	Q8WXI7	MUC16_HUMAN	Homo sapiens mucin 16, cell surface associated (MUC16), mRNA.	2118	Ser-rich.|Thr-rich.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						AAAGTACTCGCGGCTGTATTC	0.488												
MAN2B1	4125	broad.mit.edu	37	19	12768940	12768940	+	Missense_Mutation	SNP	C	C	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:12768940C>G	uc002mub.2	-	9	1322	c.1246G>C	c.(1246-1248)Gag>Cag	p.E416Q	MAN2B1_uc010dyv.1_Missense_Mutation_p.E415Q	NM_000528	NP_000519	O00754	MA2B1_HUMAN	Homo sapiens mannosidase, alpha, class 2B, member 1 (MAN2B1), transcript variant 1, mRNA.	416					protein deglycosylation	lysosome	alpha-mannosidase activity|zinc ion binding			breast(1)|central_nervous_system(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(9)|lung(10)|ovary(4)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	33						ACCAGCGCCTCCAGCTGGTTG	0.687												
IL12RB1	3594	broad.mit.edu	37	19	18171938	18171938	+	Silent	SNP	C	C	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:18171938C>A	uc002nhx.1	-	15	1956	c.1905G>T	c.(1903-1905)ggG>ggT	p.G635G	IL12RB1_uc002nhw.1_Silent_p.G595G|IL12RB1_uc010xqb.1_Silent_p.G595G	NM_005535	NP_005526	P42701	I12R1_HUMAN	Homo sapiens interleukin 12 receptor, beta 1 (IL12RB1), transcript variant 1, mRNA.	595					cellular response to interferon-gamma|interleukin-12-mediated signaling pathway|positive regulation of activated T cell proliferation|positive regulation of defense response to virus by host|positive regulation of interferon-gamma production|positive regulation of memory T cell differentiation|positive regulation of T cell mediated cytotoxicity|positive regulation of T-helper 1 type immune response|positive regulation of T-helper 17 cell lineage commitment|positive regulation of T-helper 17 type immune response	interleukin-12 receptor complex|interleukin-23 receptor complex	cytokine receptor activity			endometrium(1)|kidney(1)|lung(3)|pancreas(1)|skin(2)	8						TTACCTCCTTCCCTCCAGGGA	0.552												
MLL2	9757	broad.mit.edu	37	19	36212329	36212329	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:36212329C>T	uc021usv.1	+	2	2080	c.2080C>T	c.(2080-2082)Cgg>Tgg	p.R694W	MLL2_uc021usu.1_5'UTR	NM_014727	NP_055542	O14686	MLL2_HUMAN	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia 4 (MLL4), mRNA.	825	Pro-rich.			Missing (in Ref. 1; AAC51734).	chromatin silencing|histone H3-K4 methylation|oocyte growth|positive regulation of cell proliferation|positive regulation of estrogen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|response to estrogen stimulus|transcription, DNA-dependent	histone methyltransferase complex	histone-lysine N-methyltransferase activity|protein binding|transcription regulatory region DNA binding|zinc ion binding			NS(1)|breast(4)|central_nervous_system(38)|cervix(3)|endometrium(22)|haematopoietic_and_lymphoid_tissue(121)|kidney(35)|large_intestine(22)|lung(78)|ovary(3)|pancreas(2)|prostate(13)|skin(7)|stomach(3)|upper_aerodigestive_tract(9)|urinary_tract(5)	366						GCCTGAGCCTCGGGCAGTGGG	0.642			"""N, F, Mis"""		"""medulloblastoma, renal"""					HNSCC(34;0.089)		
NLRP12	91662	broad.mit.edu	37	19	54327194	54327194	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:54327194G>A	uc002qcj.4	-	0	455	c.235C>T	c.(235-237)Cgg>Tgg	p.R79W	NLRP12_uc002qch.4_Missense_Mutation_p.R79W|NLRP12_uc002qci.4_Missense_Mutation_p.R79W|NLRP12_uc002qck.4_Non-coding_Transcript|NLRP12_uc010eqx.3_Missense_Mutation_p.R79W	NM_144687	NP_653288	P59046	NAL12_HUMAN	Homo sapiens NLR family, pyrin domain containing 12 (NLRP12), transcript variant 2, mRNA.	79	DAPIN.				negative regulation of I-kappaB kinase/NF-kappaB cascade|negative regulation of interleukin-1 secretion|negative regulation of interleukin-6 biosynthetic process|negative regulation of protein autophosphorylation|negative regulation of Toll signaling pathway|positive regulation of inflammatory response|positive regulation of interleukin-1 beta secretion|regulation of interleukin-18 biosynthetic process|release of cytoplasmic sequestered NF-kappaB	cytoplasm	ATP binding|caspase activator activity|protein binding			NS(1)|breast(4)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(17)|liver(1)|lung(36)|ovary(5)|pancreas(2)|skin(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	80	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(134;0.026)		CTGTTTATCCGCTCAAAGGTG	0.622												
LILRB2	10288	broad.mit.edu	37	19	54782762	54782762	+	Missense_Mutation	SNP	C	C	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr19:54782762C>G	uc002qfb.3	-	5	1126	c.860G>C	c.(859-861)aGc>aCc	p.S287T	LILRB3_uc002qew.2_Intron|LILRB2_uc010eri.3_Missense_Mutation_p.S287T|LILRB2_uc010erj.3_Non-coding_Transcript|LILRB2_uc002qfc.3_Missense_Mutation_p.S287T|LILRB2_uc010yet.2_Missense_Mutation_p.S171T|LILRB2_uc010yeu.1_Non-coding_Transcript	NM_005874	NP_005865	Q8N423	LIRB2_HUMAN	Homo sapiens leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), transcript variant 1, mRNA.	287	Ig-like C2-type 3.				cell surface receptor linked signaling pathway|cell-cell signaling|cellular defense response|immune response|regulation of immune response	integral to plasma membrane|membrane fraction	receptor activity			breast(2)|endometrium(3)|kidney(1)|large_intestine(4)|lung(30)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	44	Ovarian(34;0.19)			GBM - Glioblastoma multiforme(193;0.105)		GTAGGAGCGGCTCACAGGGCC	0.647												
TUBA4B	80086	broad.mit.edu	37	2	220136351	220136351	+	Missense_Mutation	SNP	G	G	A	rs3731892	by1000genomes	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr2:220136351G>A	uc002vkv.1	+	3	821	c.656G>A	c.(655-657)aGg>aAg	p.R219K	TUBA4B_uc002vku.3_Non-coding_Transcript					Homo sapiens tubulin, alpha 4b (pseudogene) (TUBA4B), non-coding RNA.																		CTGCAGAAAAGGTATACCACG	0.552												
TUBA4B	80086	broad.mit.edu	37	2	220136371	220136371	+	Missense_Mutation	SNP	T	T	C	rs3731894	by1000genomes	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr2:220136371T>C	uc002vkv.1	+	3	841	c.676T>C	c.(676-678)Tgg>Cgg	p.W226R	TUBA4B_uc002vku.3_Non-coding_Transcript					Homo sapiens tubulin, alpha 4b (pseudogene) (TUBA4B), non-coding RNA.																		GAGCAGCTGTTGGTGGCAGAG	0.547												
SPEG	10290	broad.mit.edu	37	2	220353375	220353375	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr2:220353375G>A	uc010fwg.3	+	32	8014	c.8014G>A	c.(8014-8016)Gtg>Atg	p.V2672M		NM_005876	NP_005867	Q15772	SPEG_HUMAN	Homo sapiens SPEG complex locus (SPEG), transcript variant 1, mRNA.	2672	Ig-like 9.				muscle organ development|negative regulation of cell proliferation	nucleus	ATP binding|protein serine/threonine kinase activity	p.T2671T(1)		breast(2)|central_nervous_system(3)|endometrium(10)|kidney(2)|large_intestine(9)|lung(42)|ovary(5)|pancreas(1)|prostate(8)|skin(1)|stomach(9)|upper_aerodigestive_tract(4)|urinary_tract(4)	100		Renal(207;0.0183)		Epithelial(149;4.5e-10)|all cancers(144;7.93e-08)|Lung(261;0.00639)|LUSC - Lung squamous cell carcinoma(224;0.00829)|READ - Rectum adenocarcinoma(5;0.163)		CTCCTGTACCGTGGCTGTGGC	0.672												
CXXC11	285093	broad.mit.edu	37	2	242814085	242814085	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr2:242814085C>T	uc010fzu.1	+	1	401	c.378C>T	c.(376-378)taC>taT	p.Y126Y		NM_173821	NP_776182	Q14D33	CB085_HUMAN	Homo sapiens CXXC finger protein 11 (CXXC11), mRNA.	126						integral to membrane											AGGACTGCTACGGGGATGGCC	0.711												
DPPA4	55211	broad.mit.edu	37	3	109046838	109046838	+	Missense_Mutation	SNP	T	T	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr3:109046838T>G	uc003dxq.4	-	6	967	c.912A>C	c.(910-912)gaA>gaC	p.E304D	DPPA4_uc011bho.2_3'UTR	NM_018189	NP_060659	Q7L190	DPPA4_HUMAN	Homo sapiens developmental pluripotency associated 4 (DPPA4), mRNA.	304						nucleus	protein binding			central_nervous_system(1)|endometrium(2)|large_intestine(1)|lung(17)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	25						TGATATTCTATTCCCATTGGA	0.368												
HCLS1	3059	broad.mit.edu	37	3	121356079	121356079	+	Missense_Mutation	SNP	C	C	T	rs142478875	by1000genomes	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr3:121356079C>T	uc003eeh.4	-	6	604	c.479G>A	c.(478-480)cGg>cAg	p.R160Q	HCLS1_uc011bjj.2_Intron|HCLS1_uc011bjk.1_Non-coding_Transcript	NM_005335	NP_005326	P14317	HCLS1_HUMAN	Homo sapiens hematopoietic cell-specific Lyn substrate 1 (HCLS1), mRNA.	160					erythrocyte differentiation|intracellular signal transduction|positive regulation of cell proliferation|positive regulation of tyrosine phosphorylation of STAT protein|response to hormone stimulus	mitochondrion|nucleus|plasma membrane	DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(13)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	35				GBM - Glioblastoma multiforme(114;0.0912)		CACCCCGTACCGGCCACCAAA	0.557												
U2SURP	23350	broad.mit.edu	37	3	142741859	142741859	+	Missense_Mutation	SNP	A	A	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr3:142741859A>G	uc003evh.1	+	11	1282	c.1183A>G	c.(1183-1185)Aat>Gat	p.N395D	U2SURP_uc003evi.1_5'UTR|U2SURP_uc011bnj.1_Missense_Mutation_p.N395D|U2SURP_uc003evj.1_Non-coding_Transcript|U2SURP_uc003evk.1_Missense_Mutation_p.N394D|U2SURP_uc003evl.1_5'Flank	NM_001080415	NP_001073884	O15042	SR140_HUMAN	Homo sapiens U2 snRNP-associated SURP domain containing (U2SURP), mRNA.	395	Pro-rich.				RNA processing	nucleus	nucleotide binding|RNA binding			NS(1)|breast(2)|cervix(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(12)|ovary(2)|pancreas(1)|prostate(1)|skin(1)	31						AAAAAACCCTAATGCTCCTAT	0.418												
SLIT2	9353	broad.mit.edu	37	4	20544133	20544133	+	Silent	SNP	T	T	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr4:20544133T>C	uc003gpr.1	+	20	2364	c.2160T>C	c.(2158-2160)agT>agC	p.S720S	SLIT2_uc003gps.1_Silent_p.S712S	NM_004787	NP_004778	O94813	SLIT2_HUMAN	Homo sapiens slit homolog 2 (Drosophila) (SLIT2), mRNA.	720	LRRNT 4.				apoptosis involved in luteolysis|axon extension involved in axon guidance|branching morphogenesis of a tube|cell migration involved in sprouting angiogenesis|cellular response to heparin|cellular response to hormone stimulus|chemorepulsion involved in postnatal olfactory bulb interneuron migration|corticospinal neuron axon guidance through spinal cord|induction of negative chemotaxis|motor axon guidance|negative regulation of actin filament polymerization|negative regulation of cell growth|negative regulation of cellular response to growth factor stimulus|negative regulation of chemokine-mediated signaling pathway|negative regulation of endothelial cell migration|negative regulation of lamellipodium assembly|negative regulation of mononuclear cell migration|negative regulation of neutrophil chemotaxis|negative regulation of protein phosphorylation|negative regulation of retinal ganglion cell axon guidance|negative regulation of small GTPase mediated signal transduction|negative regulation of smooth muscle cell chemotaxis|negative regulation of vascular permeability|positive regulation of apoptosis|positive regulation of axonogenesis|response to cortisol stimulus|retinal ganglion cell axon guidance|Roundabout signaling pathway|ureteric bud development	cell surface|cytoplasm|extracellular space|plasma membrane	calcium ion binding|GTPase inhibitor activity|heparin binding|laminin-1 binding|protein homodimerization activity|proteoglycan binding|Roundabout binding			NS(1)|breast(4)|central_nervous_system(4)|cervix(1)|endometrium(5)|kidney(7)|large_intestine(17)|lung(60)|ovary(3)|pancreas(1)|prostate(2)|skin(10)|upper_aerodigestive_tract(1)	116						ATGACAATAGTTGCTCCCCAC	0.413												
PKD2	5311	broad.mit.edu	37	4	88973158	88973158	+	Missense_Mutation	SNP	A	A	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr4:88973158A>G	uc003hre.3	+	6	1651	c.1564A>G	c.(1564-1566)Ata>Gta	p.I522V	PKD2_uc011cdf.2_5'UTR|PKD2_uc011cdg.2_5'UTR|PKD2_uc011cdh.2_5'UTR	NM_000297	NP_000288	Q13563	PKD2_HUMAN	Homo sapiens polycystic kidney disease 2 (autosomal dominant) (PKD2), mRNA.	522						basal cortex|basal plasma membrane|endoplasmic reticulum|integral to membrane|lamellipodium|microtubule basal body	calcium ion binding|cytoskeletal protein binding|voltage-gated chloride channel activity|voltage-gated sodium channel activity			breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|liver(2)|lung(15)|skin(4)|upper_aerodigestive_tract(1)	36		Hepatocellular(203;0.114)|Acute lymphoblastic leukemia(40;0.221)		OV - Ovarian serous cystadenocarcinoma(123;9.98e-10)|COAD - Colon adenocarcinoma(81;0.0237)		AGTGGTAGCTATAGGAATTAA	0.323												
GPR98	84059	broad.mit.edu	37	5	90055389	90055389	+	Missense_Mutation	SNP	G	G	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr5:90055389G>T	uc003kju.3	+	57	12200	c.12104G>T	c.(12103-12105)gGa>gTa	p.G4035V	GPR98_uc003kjt.3_Missense_Mutation_p.G1741V|GPR98_uc003kjv.3_Missense_Mutation_p.G1635V	NM_032119	NP_115495	Q8WXG9	GPR98_HUMAN	Homo sapiens G protein-coupled receptor 98 (GPR98), transcript variant 1, mRNA.	4035					cell communication|cell-cell adhesion|maintenance of organ identity|neuropeptide signaling pathway|photoreceptor cell maintenance	cell surface|cytoplasm|integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity			NS(4)|breast(7)|central_nervous_system(6)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(3)|kidney(18)|large_intestine(46)|liver(2)|lung(80)|ovary(12)|pancreas(5)|prostate(1)|skin(50)|stomach(7)|upper_aerodigestive_tract(8)|urinary_tract(6)	269		all_cancers(142;1.05e-09)|all_epithelial(76;1.81e-12)|all_lung(232;5.41e-06)|Lung NSC(167;1.72e-05)|Ovarian(174;0.00948)|Colorectal(57;0.133)|Breast(839;0.192)		OV - Ovarian serous cystadenocarcinoma(54;7.01e-30)|Epithelial(54;6.79e-25)|all cancers(79;1.88e-20)		GGAGTATTTGGATTTGAAGAA	0.368												
ETF1	2107	broad.mit.edu	37	5	137846888	137846888	+	Silent	SNP	T	T	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr5:137846888T>C	uc003ldc.4	-	8	1028	c.863_splice	c.e8-1	p.G288_splice	ETF1_uc011cyv.2_Splice_Site_p.G274_splice|ETF1_uc010jex.3_Splice_Site|ETF1_uc003ldd.4_Splice_Site_p.G255_splice	NM_004730	NP_004721	P62495	ERF1_HUMAN	Homo sapiens eukaryotic translation termination factor 1 (ETF1), transcript variant 1, mRNA.	288					nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|protein methylation|regulation of translational termination	cytoplasm	protein binding|ribosome binding|translation release factor activity, codon specific			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(6)|lung(3)|ovary(2)|prostate(1)|urinary_tract(1)	18			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00325)			CAAAGTATCGTCCTACGATTA	0.368												
PCDHB6	56130	broad.mit.edu	37	5	140530986	140530986	+	Missense_Mutation	SNP	T	T	C	rs142117819	by1000genomes	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr5:140530986T>C	uc003lir.3	+	0	1148	c.1148T>C	c.(1147-1149)aTa>aCa	p.I383T		NM_018939	NP_061762	Q9Y5E3	PCDB6_HUMAN	Homo sapiens protocadherin beta 6 (PCDHB6), mRNA.	383	Cadherin 4.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to plasma membrane	calcium ion binding			cervix(1)|endometrium(14)|kidney(6)|large_intestine(16)|liver(1)|lung(33)|ovary(1)|pancreas(2)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	84			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			ATTTGTTCAATAGAGAACAAT	0.463												
PCDHB7	56129	broad.mit.edu	37	5	140554290	140554290	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr5:140554290G>A	uc003lit.3	+	0	2048	c.1874G>A	c.(1873-1875)cGt>cAt	p.R625H		NM_018940	NP_061763	Q9Y5E2	PCDB7_HUMAN	Homo sapiens protocadherin beta 7 (PCDHB7), mRNA.	625	Cadherin 6.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(2)|breast(2)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(20)|lung(54)|ovary(5)|prostate(7)|skin(7)|upper_aerodigestive_tract(4)|urinary_tract(1)	119			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GGCGAGGTGCGTACCGCCAGG	0.697												
TREML1	340205	broad.mit.edu	37	6	41121804	41121804	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr6:41121804G>A	uc011duc.2	-	1	112	c.68C>T	c.(67-69)cCt>cTt	p.P23L	TREML1_uc003opx.3_Missense_Mutation_p.P23L|TREML1_uc011dud.2_Intron	NM_178174	NP_835468	Q86YW5	TRML1_HUMAN	Homo sapiens triggering receptor expressed on myeloid cells-like 1 (TREML1), mRNA.	23	Ig-like V-type.				calcium-mediated signaling|innate immune response|platelet activation	cell surface|integral to membrane|plasma membrane|platelet alpha granule	protein binding|receptor activity			breast(2)|endometrium(2)|kidney(1)|large_intestine(2)|lung(5)|ovary(1)	13	Ovarian(28;0.0418)|Colorectal(47;0.196)					CAGCACCTCAGGGAGGCTGCC	0.607												
GFRAL	389400	broad.mit.edu	37	6	55196594	55196594	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr6:55196594C>T	uc003pcm.1	+	1	190	c.104C>T	c.(103-105)gCa>gTa	p.A35V		NM_207410	NP_997293	Q6UXV0	GFRAL_HUMAN	Homo sapiens GDNF family receptor alpha like (GFRAL), mRNA.	35						integral to membrane	receptor activity			NS(1)|breast(1)|endometrium(2)|kidney(5)|large_intestine(2)|liver(1)|lung(31)|ovary(1)|skin(2)|upper_aerodigestive_tract(2)	48	Lung NSC(77;0.0875)|Renal(3;0.122)		LUSC - Lung squamous cell carcinoma(124;0.23)			TTACGTGATGCAAATGGATGT	0.338												
BCLAF1	9774	broad.mit.edu	37	6	136599627	136599627	+	Missense_Mutation	SNP	C	C	T	rs149799182		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr6:136599627C>T	uc003qgx.1	-	3	645	c.392G>A	c.(391-393)cGg>cAg	p.R131Q	BCLAF1_uc003qgy.1_Missense_Mutation_p.R129Q|BCLAF1_uc011edc.1_Non-coding_Transcript|BCLAF1_uc011edd.1_Non-coding_Transcript|BCLAF1_uc011ede.1_Missense_Mutation_p.R129Q|BCLAF1_uc003qgw.1_Missense_Mutation_p.R131Q	NM_014739	NP_055554	Q9NYF8	BCLF1_HUMAN	Homo sapiens BCL2-associated transcription factor 1 (BCLAF1), transcript variant 1, mRNA.	131					induction of apoptosis|negative regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleolus	DNA binding|protein binding	p.R131P(1)		haematopoietic_and_lymphoid_tissue(3)|large_intestine(4)|ovary(1)|skin(1)	9	Colorectal(23;0.24)			GBM - Glioblastoma multiforme(68;0.00226)|OV - Ovarian serous cystadenocarcinoma(155;0.00331)		TCTATATGACCGGCGAGATCT	0.448												
USP42	84132	broad.mit.edu	37	7	6183728	6183728	+	Missense_Mutation	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:6183728G>A	uc011jwo.1	+	8	1014	c.891G>A	c.(889-891)atG>atA	p.M297I	USP42_uc011jwn.1_Missense_Mutation_p.M142I|USP42_uc010kth.1_Missense_Mutation_p.M230I|USP42_uc011jwp.2_Missense_Mutation_p.M297I|USP42_uc011jwq.2_Missense_Mutation_p.M104I|USP42_uc011jwr.1_Missense_Mutation_p.M142I	NM_032172	NP_115548	Q9H9J4	UBP42_HUMAN	Homo sapiens ubiquitin specific peptidase 42 (USP42), mRNA.	297					cell differentiation|protein deubiquitination|spermatogenesis|ubiquitin-dependent protein catabolic process		cysteine-type peptidase activity|ubiquitin thiolesterase activity			breast(1)|central_nervous_system(1)|endometrium(5)|kidney(4)|large_intestine(2)|lung(14)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(1)	35		Ovarian(82;0.0423)		UCEC - Uterine corpus endometrioid carcinoma (126;0.108)|OV - Ovarian serous cystadenocarcinoma(56;5.77e-14)		GTAAAAAGATGGTTCCAGCTT	0.333												
URGCP	55665	broad.mit.edu	37	7	43917037	43917037	+	Silent	SNP	G	G	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:43917037G>C	uc003tiw.3	-	5	2082	c.2025C>G	c.(2023-2025)gtC>gtG	p.V675V	URGCP_uc022acg.1_Intron|URGCP_uc003tiu.3_Silent_p.V632V|URGCP_uc003tiv.3_Silent_p.V600V|URGCP_uc003tix.3_Silent_p.V666V|URGCP_uc003tiy.3_Silent_p.V632V|URGCP_uc003tiz.3_Silent_p.V632V|URGCP_uc011kbj.2_Silent_p.V632V	NM_001077663	NP_001071131	Q8TCY9	URGCP_HUMAN	Homo sapiens upregulator of cell proliferation (URGCP), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA.	675					cell cycle	centrosome|nucleus	GTP binding			breast(3)|endometrium(4)|kidney(2)|large_intestine(3)|liver(1)|lung(13)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	34						GGAGCCCTGTGACCCAGCGGA	0.642												
URGCP	55665	broad.mit.edu	37	7	43917123	43917123	+	Missense_Mutation	SNP	G	G	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:43917123G>T	uc003tiw.3	-	5	1996	c.1939C>A	c.(1939-1941)Cca>Aca	p.P647T	URGCP_uc022acg.1_Intron|URGCP_uc003tiu.3_Missense_Mutation_p.P604T|URGCP_uc003tiv.3_Missense_Mutation_p.P572T|URGCP_uc003tix.3_Missense_Mutation_p.P638T|URGCP_uc003tiy.3_Missense_Mutation_p.P604T|URGCP_uc003tiz.3_Missense_Mutation_p.P604T|URGCP_uc011kbj.2_Missense_Mutation_p.P604T	NM_001077663	NP_001071131	Q8TCY9	URGCP_HUMAN	Homo sapiens upregulator of cell proliferation (URGCP), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA.	647					cell cycle	centrosome|nucleus	GTP binding			breast(3)|endometrium(4)|kidney(2)|large_intestine(3)|liver(1)|lung(13)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	34						GCCAAGCCTGGGAAGTGGGCA	0.622												
URGCP	55665	broad.mit.edu	37	7	43918034	43918034	+	Missense_Mutation	SNP	G	G	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:43918034G>C	uc003tiw.3	-	5	1085	c.1028C>G	c.(1027-1029)tCt>tGt	p.S343C	URGCP_uc022acg.1_Intron|URGCP_uc003tiu.3_Missense_Mutation_p.S300C|URGCP_uc003tiv.3_Missense_Mutation_p.S268C|URGCP_uc003tix.3_Missense_Mutation_p.S334C|URGCP_uc003tiy.3_Missense_Mutation_p.S300C|URGCP_uc003tiz.3_Missense_Mutation_p.S300C|URGCP_uc011kbj.2_Missense_Mutation_p.S300C	NM_001077663	NP_001071131	Q8TCY9	URGCP_HUMAN	Homo sapiens upregulator of cell proliferation (URGCP), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA.	343					cell cycle	centrosome|nucleus	GTP binding			breast(3)|endometrium(4)|kidney(2)|large_intestine(3)|liver(1)|lung(13)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	34						CAGCCAGTGAGACCCGATGTC	0.458												
URGCP	55665	broad.mit.edu	37	7	43918768	43918768	+	Missense_Mutation	SNP	G	G	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:43918768G>C	uc003tiw.3	-	5	351	c.294C>G	c.(292-294)atC>atG	p.I98M	URGCP_uc022acg.1_Intron|URGCP_uc003tiu.3_Missense_Mutation_p.I55M|URGCP_uc003tiv.3_Missense_Mutation_p.I23M|URGCP_uc003tix.3_Missense_Mutation_p.I89M|URGCP_uc003tiy.3_Missense_Mutation_p.I55M|URGCP_uc003tiz.3_Missense_Mutation_p.I55M|URGCP_uc011kbj.2_Missense_Mutation_p.I55M	NM_001077663	NP_001071131	Q8TCY9	URGCP_HUMAN	Homo sapiens upregulator of cell proliferation (URGCP), nuclear gene encoding mitochondrial protein, transcript variant 3, mRNA.	98					cell cycle	centrosome|nucleus	GTP binding			breast(3)|endometrium(4)|kidney(2)|large_intestine(3)|liver(1)|lung(13)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	34						TGTCAAAACTGATCTGCAGAG	0.507												
EGFR	1956	broad.mit.edu	37	7	55224307	55224307	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:55224307C>T	uc003tqk.3	+	8	1334	c.1088C>T	c.(1087-1089)aCc>aTc	p.T363I	EGFR_uc003tqh.3_Missense_Mutation_p.T363I|EGFR_uc003tqi.3_Missense_Mutation_p.T363I|EGFR_uc003tqj.3_Missense_Mutation_p.T363I|EGFR_uc022adm.1_Missense_Mutation_p.T363I|EGFR_uc010kzg.2_Missense_Mutation_p.T318I|EGFR_uc022adn.1_Missense_Mutation_p.T318I|EGFR_uc011kco.2_Missense_Mutation_p.T310I|EGFR_uc011kcp.1_Non-coding_Transcript|EGFR_uc011kcq.1_Non-coding_Transcript	NM_005228	NP_005219	P00533	EGFR_HUMAN	Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1, mRNA.	363					activation of phospholipase A2 activity by calcium-mediated signaling|activation of phospholipase C activity|axon guidance|cell proliferation|cell-cell adhesion|negative regulation of apoptosis|negative regulation of epidermal growth factor receptor signaling pathway|ossification|positive regulation of catenin import into nucleus|positive regulation of cell migration|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|positive regulation of epithelial cell proliferation|positive regulation of MAP kinase activity|positive regulation of nitric oxide biosynthetic process|positive regulation of phosphorylation|positive regulation of protein kinase B signaling cascade|protein autophosphorylation|protein insertion into membrane|regulation of nitric-oxide synthase activity|regulation of peptidyl-tyrosine phosphorylation|response to stress|response to UV-A	basolateral plasma membrane|endoplasmic reticulum membrane|endosome|extracellular space|Golgi membrane|integral to membrane|nuclear membrane|Shc-EGFR complex	actin filament binding|ATP binding|double-stranded DNA binding|epidermal growth factor receptor activity|identical protein binding|MAP/ERK kinase kinase activity|protein heterodimerization activity|protein phosphatase binding|receptor signaling protein tyrosine kinase activity			NS(2)|adrenal_gland(5)|biliary_tract(8)|bone(3)|breast(18)|central_nervous_system(106)|endometrium(26)|eye(3)|haematopoietic_and_lymphoid_tissue(9)|kidney(11)|large_intestine(85)|liver(2)|lung(13575)|oesophagus(21)|ovary(38)|pancreas(3)|peritoneum(11)|pleura(2)|prostate(35)|salivary_gland(11)|skin(9)|small_intestine(1)|soft_tissue(4)|stomach(41)|thymus(2)|thyroid(14)|upper_aerodigestive_tract(59)|urinary_tract(6)	14110	all_cancers(1;1.57e-46)|all_epithelial(1;5.62e-37)|Lung NSC(1;9.29e-25)|all_lung(1;4.39e-23)|Esophageal squamous(2;7.55e-08)|Breast(14;0.0318)		GBM - Glioblastoma multiforme(1;0)|all cancers(1;2.19e-314)|Lung(13;4.65e-05)|LUSC - Lung squamous cell carcinoma(13;0.000168)|STAD - Stomach adenocarcinoma(5;0.00164)|Epithelial(13;0.0607)		Cetuximab(DB00002)|Erlotinib(DB00530)|Gefitinib(DB00317)|Lapatinib(DB01259)|Lidocaine(DB00281)|Panitumumab(DB01269)|Trastuzumab(DB00072)	AAAAACTGCACCTCCATCAGT	0.413		8	"""A, O, Mis"""		"""glioma, NSCLC"""	NSCLC			Lung Cancer, Familial Clustering of	TCGA GBM(3;<1E-08)|TSP Lung(4;<1E-08)		
NCF1	653361	broad.mit.edu	37	7	74193497	74193497	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:74193497C>T	uc003ubb.3	+	2	293	c.223C>T	c.(223-225)Ctc>Ttc	p.L75F	NCF1_uc010lbs.1_Missense_Mutation_p.L75F|NCF1_uc011kfh.1_Intron	NM_000265	NP_000256	P14598	NCF1_HUMAN	Homo sapiens neutrophil cytosolic factor 1 (NCF1), mRNA.	75	PX.				cell communication|cellular defense response|innate immune response|protein targeting to membrane|respiratory burst|superoxide anion generation	cytosol|NADPH oxidase complex|soluble fraction	electron carrier activity|GTP binding|GTPase activity|phosphatidylinositol binding|SH3 domain binding|superoxide-generating NADPH oxidase activity			breast(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(2)|skin(3)	10						CATCCCCCACCTCCCAGGTGA	0.552												
TRIM4	89122	broad.mit.edu	37	7	99516656	99516656	+	Silent	SNP	G	G	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:99516656G>A	uc003usd.3	-	0	568	c.369C>T	c.(367-369)atC>atT	p.I123I	TRIM4_uc003use.3_Silent_p.I123I|TRIM4_uc011kjc.2_5'UTR|TRIM4_uc003usf.3_Silent_p.I123I	NM_033017	NP_148977	Q9C037	TRIM4_HUMAN	Homo sapiens tripartite motif containing 4 (TRIM4), transcript variant alpha, mRNA.	123					protein trimerization	cytoplasm|plasma membrane	zinc ion binding			breast(2)|endometrium(1)|kidney(1)|large_intestine(3)|lung(8)|ovary(1)|skin(1)	17	Esophageal squamous(72;0.0166)|Lung NSC(181;0.0211)|all_lung(186;0.0323)	Ovarian(593;0.238)				AGGCCTCGTCGATGGGTGCCA	0.612												
LHFPL3	375612	broad.mit.edu	37	7	103969236	103969237	+	In_Frame_Ins	INS	-	-	GCC			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:103969236_103969237insGCC	uc003vce.3	+	0	133_134	c.9_10insGCC	c.(7-12)insGCC	p.14_15insA	LHFPL3_uc003vcf.3_In_Frame_Ins_p.14_15insA|JA682610_uc022ajt.1_5'Flank	NM_199000	NP_945351	Q86UP9	LHPL3_HUMAN	Homo sapiens lipoma HMGIC fusion partner-like 3 (LHFPL3), mRNA.	0						integral to membrane				kidney(1)|large_intestine(2)|lung(6)	9						gAATGCCCGGAgccgccgccgc	0.728												
PIK3CG	5294	broad.mit.edu	37	7	106508126	106508126	+	Silent	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:106508126C>T	uc003vdv.4	+	1	205	c.120C>T	c.(118-120)atC>atT	p.I40I	PIK3CG_uc003vdu.3_Silent_p.I40I|PIK3CG_uc003vdw.3_Silent_p.I40I	NM_002649	NP_002640	P48736	PK3CG_HUMAN	Homo sapiens phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG), mRNA.	40					G-protein coupled receptor protein signaling pathway|phosphatidylinositol-mediated signaling|platelet activation	phosphatidylinositol 3-kinase complex	1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity|protein binding			breast(7)|central_nervous_system(9)|cervix(1)|endometrium(6)|kidney(4)|large_intestine(16)|liver(4)|lung(59)|ovary(4)|pancreas(4)|prostate(3)|skin(6)|stomach(3)|upper_aerodigestive_tract(5)|urinary_tract(1)	132						TCATCCCCATCGAGTTCGTGC	0.662												
C7orf66	154907	broad.mit.edu	37	7	108524126	108524126	+	Missense_Mutation	SNP	G	G	A	rs143724624		TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:108524126G>A	uc003vfo.3	-	1	334	c.286C>T	c.(286-288)Cgg>Tgg	p.R96W		NM_001024607	NP_001019778	A4D0T2	CG066_HUMAN	Homo sapiens chromosome 7 open reading frame 66 (C7orf66), mRNA.	96						integral to membrane		p.R96Q(1)		breast(1)|kidney(3)|large_intestine(2)|lung(7)|ovary(2)	15						TGGACAATCCGTAGATATGCA	0.348												
GPR37	2861	broad.mit.edu	37	7	124387325	124387325	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:124387325C>T	uc003vli.3	-	1	1747	c.1096G>A	c.(1096-1098)Gta>Ata	p.V366I		NM_005302	NP_005293	O15354	GPR37_HUMAN	Homo sapiens G protein-coupled receptor 37 (endothelin receptor type B-like) (GPR37), mRNA.	366						endoplasmic reticulum membrane|integral to plasma membrane	G-protein coupled receptor activity			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(5)|large_intestine(8)|lung(11)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	36						TACATCTGTACGTTGGTGGCA	0.463												
AKR1B10	57016	broad.mit.edu	37	7	134212671	134212671	+	Missense_Mutation	SNP	C	C	T			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr7:134212671C>T	uc003vrr.3	+	0	328	c.8C>T	c.(7-9)aCg>aTg	p.T3M		NM_020299	NP_064695	O60218	AK1BA_HUMAN	Homo sapiens aldo-keto reductase family 1, member B10 (aldose reductase) (AKR1B10), mRNA.	3					cellular aldehyde metabolic process|digestion|steroid metabolic process	cytoplasm	aldo-keto reductase (NADP) activity|protein binding			NS(1)|central_nervous_system(1)|kidney(1)|large_intestine(3)|lung(9)|skin(5)	20						ACCATGGCCACGTTTGTGGAG	0.502												
EBF2	64641	broad.mit.edu	37	8	25718712	25718712	+	Missense_Mutation	SNP	C	C	A			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr8:25718712C>A	uc003xes.2	-	12	1460	c.1195G>T	c.(1195-1197)Gct>Tct	p.A399S	DOCK5_uc003xek.3_Intron|EBF2_uc010lug.2_Non-coding_Transcript	NM_022659	NP_073150	Q9HAK2	COE2_HUMAN	Homo sapiens early B-cell factor 2 (EBF2), mRNA.	399					multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|metal ion binding	p.I398F(1)		endometrium(3)|kidney(2)|large_intestine(3)|lung(22)|ovary(3)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(2)	39		all_cancers(63;0.0989)|Ovarian(32;2.74e-05)|all_epithelial(46;0.0608)|Prostate(55;0.0845)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0277)|Epithelial(17;3.29e-10)|Colorectal(74;0.00383)|COAD - Colon adenocarcinoma(73;0.00738)		AGAGCTTCAGCAATGTCTGCG	0.493												
LY96	23643	broad.mit.edu	37	8	74922304	74922304	+	Missense_Mutation	SNP	A	A	G			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr8:74922304A>G	uc003yad.3	+	2	385	c.271A>G	c.(271-273)Aaa>Gaa	p.K91E	LY96_uc022awb.1_Missense_Mutation_p.K61E	NM_015364	NP_056179	Q9Y6Y9	LY96_HUMAN	Homo sapiens lymphocyte antigen 96 (LY96), transcript variant 1, mRNA.	91					cellular defense response|detection of lipopolysaccharide|I-kappaB kinase/NF-kappaB cascade|inflammatory response|innate immune response|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway	extracellular space|lipopolysaccharide receptor complex|plasma membrane	coreceptor activity|lipopolysaccharide receptor activity|protein binding	p.R90C(2)		endometrium(1)|large_intestine(2)|lung(1)|upper_aerodigestive_tract(1)	5	Breast(64;0.0311)		Epithelial(68;0.0208)|BRCA - Breast invasive adenocarcinoma(89;0.0499)|all cancers(69;0.0619)			TCCAAAGCGCAAAGAAGTTAT	0.343												
TAF2	6873	broad.mit.edu	37	8	120831592	120831592	+	Nonsense_Mutation	SNP	G	G	C			TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr8:120831592G>C	uc003you.3	-	2	563	c.293C>G	c.(292-294)tCa>tGa	p.S98*		NM_003184	NP_003175	Q6P1X5	TAF2_HUMAN	Homo sapiens TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa (TAF2), mRNA.	98					G2/M transition of mitotic cell cycle|positive regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	transcription factor TFIID complex|transcription factor TFTC complex	metallopeptidase activity|protein binding|transcription regulatory region DNA binding|zinc ion binding			NS(2)|breast(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(10)|lung(21)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	49	Lung NSC(37;9.35e-07)|Ovarian(258;0.011)|Hepatocellular(40;0.161)		STAD - Stomach adenocarcinoma(47;0.00185)			TTACTGTTTTGATTCACTGTG	0.289												
C9orf131	138724	broad.mit.edu	37	9	35045372	35045372	+	Missense_Mutation	SNP	C	C	G	rs3739871	byFrequency	TCGA-14-1829-01A-01W-0643-08	TCGA-14-1829-10A-01W-0644-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	c69ca476-9e11-4f6e-a4f5-6952f792a580	e73172bd-bb87-4131-901c-5f3eb2117df8	g.chr9:35045372C>G	uc003zvw.3	+	1	2775	c.2746C>G	c.(2746-2748)Cca>Gca	p.P916A	C9orf131_uc003zvu.3_Missense_Mutation_p.P868A|C9orf131_uc003zvv.3_Missense_Mutation_p.P843A|C9orf131_uc003zvx.3_Missense_Mutation_p.P881A	NM_203299	NP_976044	Q5VYM1	CI131_HUMAN	Homo sapiens chromosome 9 open reading frame 131 (C9orf131), transcript variant 1, mRNA.	916			P -> S (in dbSNP:rs3739871).							cervix(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(23)|prostate(2)|skin(2)|stomach(1)	39	all_epithelial(49;0.22)		LUSC - Lung squamous cell carcinoma(32;0.00117)|Lung(28;0.00309)			CTATCTATCTCCAGGCCCAGG	0.537												
