#version 2.4
## 
## Oncotator v1.8.0.0 | Flat File Reference hg19 | GENCODE v19 EFFECT | UniProt_AAxform 2014_12 | ClinVar 12.03.20 | ESP 6500SI-V2 | ORegAnno UCSC Track | dbSNP build 142 | CCLE_By_GP 09292010 | COSMIC v62_291112 | 1000gp3 20130502 | UniProt_AA 2014_12 | dbNSFP v2.4 | ESP 6500SI-V2 | COSMIC_FusionGenes v62_291112 | gencode_xref_refseq metadata_v19 | CCLE_By_Gene 09292010 | ACHILLES_Lineage_Results 110303 | CGC full_2012-03-15 | UniProt 2014_12 | HumanDNARepairGenes 20110905 | HGNC Sept172014 | COSMIC_Tissue 291112 | Familial_Cancer_Genes 20110905 | TUMORScape 20100104 | Ensembl ICGC MUCOPA | TCGAScape 110405 | MutSig Published Results 20110905 
Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	i_1000gp3_AA	i_1000gp3_AC	i_1000gp3_AF	i_1000gp3_AFR_AF	i_1000gp3_AMR_AF	i_1000gp3_AN	i_1000gp3_CIEND	i_1000gp3_CIPOS	i_1000gp3_CS	i_1000gp3_DP	i_1000gp3_EAS_AF	i_1000gp3_END	i_1000gp3_EUR_AF	i_1000gp3_IMPRECISE	i_1000gp3_MC	i_1000gp3_MEINFO	i_1000gp3_MEND	i_1000gp3_MLEN	i_1000gp3_MSTART	i_1000gp3_NS	i_1000gp3_SAS_AF	i_1000gp3_SVLEN	i_1000gp3_SVTYPE	i_1000gp3_TSD	i_ACHILLES_Lineage_Results_Top_Genes	i_Annotation_Transcript	i_CCLE_ONCOMAP_overlapping_mutations	i_CCLE_ONCOMAP_total_mutations_in_gene	i_CGC_Cancer Germline Mut	i_CGC_Cancer Molecular Genetics	i_CGC_Cancer Somatic Mut	i_CGC_Cancer Syndrome	i_CGC_Chr	i_CGC_Chr Band	i_CGC_GeneID	i_CGC_Mutation_Type	i_CGC_Name	i_CGC_Other Germline Mut	i_CGC_Other_Diseases	i_CGC_Tissue Type	i_CGC_Translocation_Partner	i_CGC_Tumor_Types_Germline	i_CGC_Tumor_Types_Somatic	i_COSMIC_fusion_genes	i_COSMIC_n_overlapping_mutations	i_COSMIC_overlapping_mutation_descriptions	i_COSMIC_overlapping_mutations	i_COSMIC_overlapping_primary_sites	i_COSMIC_tissue_types_affected	i_COSMIC_total_alterations_in_gene	i_ClinVar_ASSEMBLY	i_ClinVar_HGMD_ID	i_ClinVar_SYM	i_ClinVar_TYPE	i_ClinVar_rs	i_Codon_Change	i_DNARepairGenes_Role	i_Description	i_DrugBank	i_ESP_AA	i_ESP_AAC	i_ESP_AA_AC	i_ESP_AA_AGE	i_ESP_AA_GTC	i_ESP_AvgAAsampleReadDepth	i_ESP_AvgEAsampleReadDepth	i_ESP_AvgSampleReadDepth	i_ESP_CA	i_ESP_CDP	i_ESP_CG	i_ESP_CP	i_ESP_Chromosome	i_ESP_DBSNP	i_ESP_DP	i_ESP_EA_AC	i_ESP_EA_AGE	i_ESP_EA_GTC	i_ESP_EXOME_CHIP	i_ESP_FG	i_ESP_GL	i_ESP_GM	i_ESP_GS	i_ESP_GTC	i_ESP_GTS	i_ESP_GWAS_PUBMED	i_ESP_MAF	i_ESP_PH	i_ESP_PP	i_ESP_Position	i_ESP_TAC	i_ESP_TotalAAsamplesCovered	i_ESP_TotalEAsamplesCovered	i_ESP_TotalSamplesCovered	i_Ensembl_so_accession	i_Ensembl_so_term	i_Entrez_Gene_Id	i_FamilialCancerDatabase_Syndromes	i_Familial_Cancer_Genes_Reference	i_Familial_Cancer_Genes_Synonym	i_GO_Biological_Process	i_GO_Cellular_Component	i_GO_Molecular_Function	i_Genome_Change	i_HGNC_Accession Numbers	i_HGNC_CCDS IDs	i_HGNC_Chromosome	i_HGNC_Date Modified	i_HGNC_Date Name Changed	i_HGNC_Date Symbol Changed	i_HGNC_Ensembl Gene ID	i_HGNC_Ensembl ID(supplied by Ensembl)	i_HGNC_Enzyme IDs	i_HGNC_Gene family description	i_HGNC_HGNC ID	i_HGNC_Locus Group	i_HGNC_Locus Type	i_HGNC_Name Synonyms	i_HGNC_OMIM ID(supplied by NCBI)	i_HGNC_Previous Names	i_HGNC_Previous Symbols	i_HGNC_Primary IDs	i_HGNC_Pubmed IDs	i_HGNC_Record Type	i_HGNC_RefSeq(supplied by NCBI)	i_HGNC_Secondary IDs	i_HGNC_Status	i_HGNC_Synonyms	i_HGNC_UCSC ID(supplied by UCSC)	i_HGNC_UniProt ID(supplied by UniProt)	i_HGNC_VEGA IDs	i_HGVS_coding_DNA_change	i_HGVS_genomic_change	i_HGVS_protein_change	i_MUTSIG_Published_Results	i_OREGANNO_ID	i_OREGANNO_Values	i_ORegAnno_bin	i_Other_Transcripts	i_Protein_Change	i_Refseq_mRNA_Id	i_Refseq_prot_Id	i_SwissProt_acc_Id	i_SwissProt_entry_Id	i_TCGAscape_Amplification_Peaks	i_TCGAscape_Deletion_Peaks	i_Transcript_Exon	i_Transcript_Position	i_Transcript_Strand	i_Tumorscape_Amplification_Peaks	i_Tumorscape_Deletion_Peaks	i_UniProt_AApos	i_UniProt_Experimental_Info	i_UniProt_Natural_Variations	i_UniProt_Region	i_UniProt_Site	i_UniProt_alt_uniprot_accessions	i_Variant_Classification	i_Variant_Type	i_annotation_transcript	i_build	i_cDNA_Change	i_ccds_id	i_dbNSFP_1000Gp1_AC	i_dbNSFP_1000Gp1_AF	i_dbNSFP_1000Gp1_AFR_AC	i_dbNSFP_1000Gp1_AFR_AF	i_dbNSFP_1000Gp1_AMR_AC	i_dbNSFP_1000Gp1_AMR_AF	i_dbNSFP_1000Gp1_ASN_AC	i_dbNSFP_1000Gp1_ASN_AF	i_dbNSFP_1000Gp1_EUR_AC	i_dbNSFP_1000Gp1_EUR_AF	i_dbNSFP_Ancestral_allele	i_dbNSFP_CADD_phred	i_dbNSFP_CADD_raw	i_dbNSFP_CADD_raw_rankscore	i_dbNSFP_ESP6500_AA_AF	i_dbNSFP_ESP6500_EA_AF	i_dbNSFP_Ensembl_geneid	i_dbNSFP_Ensembl_transcriptid	i_dbNSFP_FATHMM_pred	i_dbNSFP_FATHMM_rankscore	i_dbNSFP_FATHMM_score	i_dbNSFP_GERP++_NR	i_dbNSFP_GERP++_RS	i_dbNSFP_GERP++_RS_rankscore	i_dbNSFP_Interpro_domain	i_dbNSFP_LRT_Omega	i_dbNSFP_LRT_converted_rankscore	i_dbNSFP_LRT_pred	i_dbNSFP_LRT_score	i_dbNSFP_LR_pred	i_dbNSFP_LR_rankscore	i_dbNSFP_LR_score	i_dbNSFP_MutationAssessor_pred	i_dbNSFP_MutationAssessor_rankscore	i_dbNSFP_MutationAssessor_score	i_dbNSFP_MutationTaster_converted_rankscore	i_dbNSFP_MutationTaster_pred	i_dbNSFP_MutationTaster_score	i_dbNSFP_Polyphen2_HDIV_pred	i_dbNSFP_Polyphen2_HDIV_rankscore	i_dbNSFP_Polyphen2_HDIV_score	i_dbNSFP_Polyphen2_HVAR_pred	i_dbNSFP_Polyphen2_HVAR_rankscore	i_dbNSFP_Polyphen2_HVAR_score	i_dbNSFP_RadialSVM_pred	i_dbNSFP_RadialSVM_rankscore	i_dbNSFP_RadialSVM_score	i_dbNSFP_Reliability_index	i_dbNSFP_SIFT_converted_rankscore	i_dbNSFP_SIFT_pred	i_dbNSFP_SIFT_score	i_dbNSFP_SLR_test_statistic	i_dbNSFP_SiPhy_29way_logOdds	i_dbNSFP_SiPhy_29way_logOdds_rankscore	i_dbNSFP_SiPhy_29way_pi	i_dbNSFP_UniSNP_ids	i_dbNSFP_Uniprot_aapos	i_dbNSFP_Uniprot_acc	i_dbNSFP_Uniprot_id	i_dbNSFP_aaalt	i_dbNSFP_aapos	i_dbNSFP_aapos_FATHMM	i_dbNSFP_aapos_SIFT	i_dbNSFP_aaref	i_dbNSFP_cds_strand	i_dbNSFP_codonpos	i_dbNSFP_fold-degenerate	i_dbNSFP_genename	i_dbNSFP_hg18_pos(1-coor)	i_dbNSFP_phastCons100way_vertebrate	i_dbNSFP_phastCons100way_vertebrate_rankscore	i_dbNSFP_phastCons46way_placental	i_dbNSFP_phastCons46way_placental_rankscore	i_dbNSFP_phastCons46way_primate	i_dbNSFP_phastCons46way_primate_rankscore	i_dbNSFP_phyloP100way_vertebrate	i_dbNSFP_phyloP100way_vertebrate_rankscore	i_dbNSFP_phyloP46way_placental	i_dbNSFP_phyloP46way_placental_rankscore	i_dbNSFP_phyloP46way_primate	i_dbNSFP_phyloP46way_primate_rankscore	i_dbNSFP_refcodon	i_entrez_gene_id	i_gc_content_full	i_gencode_transcript_name	i_gencode_transcript_status	i_gencode_transcript_tags	i_gencode_transcript_type	i_gene_type	i_havana_transcript	i_refseq_mrna_id	i_secondary_variant_classification	i_t_alt_count_full	i_t_ref_count_full	isArtifactMode	oxoGCut	pox	pox_cutoff	qox	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample
OR10P1	121130	broad.mit.edu	37	12	56031094	56031094	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr12:56031094G>A	ENST00000309675.2	+	1	451	c.419G>A	c.(418-420)cGg>cAg	p.R140Q	RP11-644F5.16_ENST00000556606.1_RNA	NM_206899.1	NP_996782.1	Q8NGE3	O10P1_HUMAN	olfactory receptor, family 10, subfamily P, member 1	140						integral component of membrane (GO:0016021)|plasma membrane (GO:0005886)	G-protein coupled receptor activity (GO:0004930)|olfactory receptor activity (GO:0004984)	p.R140Q(1)		autonomic_ganglia(1)|central_nervous_system(2)|endometrium(4)|large_intestine(3)|lung(6)|pancreas(1)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	26						TTGAGCCCACGGGCCTGCATG	0.617																																						ENST00000309675.2																			1	Substitution - Missense(1)	p.R140Q(1)	prostate(1)	autonomic_ganglia(1)|central_nervous_system(2)|endometrium(4)|large_intestine(3)|lung(6)|pancreas(1)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	26						c.(418-420)cGg>cAg		olfactory receptor, family 10, subfamily P, member 1							107.0	81.0	90.0					12																	56031094		2203	4300	6503	SO:0001583	missense	121130				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	g.chr12:56031094G>A	BK004259	CCDS31828.1	12q13.13	2012-08-09		2004-03-10		ENSG00000175398		"""GPCR / Class A : Olfactory receptors"""	15378	protein-coding gene	gene with protein product				OR10P1P, OR10P2P, OR10P3P			Standard	NM_206899		Approved	OST701	uc010spq.2	Q8NGE3	OTTHUMG00000169961	ENST00000309675.2:c.419G>A	12.37:g.56031094G>A	ENSP00000308082:p.Arg140Gln						p.R140Q	NM_206899.1	NP_996782.1	Q8NGE3	O10P1_HUMAN			1	451	+			140					B9EGY4	Missense_Mutation	SNP	ENST00000309675.2	37	c.419G>A	CCDS31828.1	.	.	.	.	.	.	.	.	.	.	G	3.917	-0.018967	0.07681	.	.	ENSG00000175398	ENST00000309675	T	0.01527	4.8	4.34	-6.59	0.01830	GPCR, rhodopsin-like superfamily (1);	1.178510	0.06409	N	0.720282	T	0.01730	0.0055	L	0.39085	1.19	0.09310	N	1	B	0.19583	0.037	B	0.15484	0.013	T	0.41893	-0.9483	10	0.32370	T	0.25	.	10.3035	0.43667	0.6963:0.1146:0.1891:0.0	.	140	Q8NGE3	O10P1_HUMAN	Q	140	ENSP00000308082:R140Q	ENSP00000308082:R140Q	R	+	2	0	OR10P1	54317361	0.000000	0.05858	0.000000	0.03702	0.000000	0.00434	-2.416000	0.01035	-1.452000	0.01931	-0.254000	0.11334	CGG		0.617	OR10P1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000406680.1			7	69	0	0	0	0.029380	0	7	69				
LACTB	114294	broad.mit.edu	37	15	63421818	63421818	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr15:63421818G>A	ENST00000261893.4	+	5	1159	c.1087G>A	c.(1087-1089)Gaa>Aaa	p.E363K	LACTB_ENST00000413507.2_Missense_Mutation_p.E363K|RPS27L_ENST00000559763.1_Intron	NM_032857.3	NP_116246.2	P83111	LACTB_HUMAN	lactamase, beta	363						cytoplasm (GO:0005737)|mitochondrion (GO:0005739)	hydrolase activity (GO:0016787)	p.E363K(1)		NS(1)|breast(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|skin(1)|stomach(1)	12						TGTGCAGGAAGAAAACGAGCC	0.373																																					Melanoma(85;443 1381 6215 27308 35583)	ENST00000413507.2																			1	Substitution - Missense(1)	p.E363K(1)	prostate(1)	NS(1)|breast(1)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|skin(1)|stomach(1)	12						c.(1087-1089)Gaa>Aaa		lactamase, beta							86.0	85.0	85.0					15																	63421818		2203	4300	6503	SO:0001583	missense	114294					mitochondrion	hydrolase activity	g.chr15:63421818G>A	AK027808	CCDS10182.1, CCDS45275.1	15q22.1	2012-11-14	2001-12-12	2001-12-14	ENSG00000103642	ENSG00000103642		"""Mitochondrial ribosomal proteins / large subunits"""	16468	protein-coding gene	gene with protein product		608440	"""mitochondrial ribosomal protein L56"""	MRPL56		11707067	Standard	NM_032857		Approved	FLJ14902	uc002alw.3	P83111	OTTHUMG00000132807	ENST00000261893.4:c.1087G>A	15.37:g.63421818G>A	ENSP00000261893:p.Glu363Lys					RPS27L_ENST00000559763.1_Intron|LACTB_ENST00000261893.4_Missense_Mutation_p.E363K	p.E363K	NM_171846.2	NP_741982.1	P83111	LACTB_HUMAN			5	1126	+			363					P83096	Missense_Mutation	SNP	ENST00000261893.4	37	c.1087G>A	CCDS10182.1	.	.	.	.	.	.	.	.	.	.	G	17.05	3.289043	0.59976	.	.	ENSG00000103642	ENST00000261893;ENST00000413507	T;T	0.43294	0.95;0.99	5.32	5.32	0.75619	Beta-lactamase/transpeptidase-like (2);Beta-lactamase-related (1);	0.095872	0.64402	D	0.000001	T	0.40546	0.1121	M	0.66939	2.045	0.80722	D	1	B	0.29232	0.238	B	0.27380	0.079	T	0.38520	-0.9657	10	0.06365	T	0.9	-23.3635	17.9923	0.89172	0.0:0.0:1.0:0.0	.	363	P83111	LACTB_HUMAN	K	363	ENSP00000261893:E363K;ENSP00000392956:E363K	ENSP00000261893:E363K	E	+	1	0	LACTB	61208871	1.000000	0.71417	0.999000	0.59377	0.992000	0.81027	7.181000	0.77682	2.465000	0.83290	0.557000	0.71058	GAA		0.373	LACTB-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000256224.1	NM_032857		4	60	0	0	0	0.029380	0	4	60				
NECAP2	55707	broad.mit.edu	37	1	16778446	16778446	+	Silent	SNP	T	T	C			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr1:16778446T>C	ENST00000337132.5	+	6	693	c.603T>C	c.(601-603)ccT>ccC	p.P201P	NECAP2_ENST00000457722.2_Silent_p.P175P|NECAP2_ENST00000406746.1_Silent_p.P201P|NECAP2_ENST00000504551.2_Silent_p.P140P|NECAP2_ENST00000443980.2_Silent_p.P201P	NM_001145278.1|NM_018090.4	NP_001138750.1|NP_060560.1	Q9NVZ3	NECP2_HUMAN	NECAP endocytosis associated 2	201					endocytosis (GO:0006897)|protein transport (GO:0015031)	clathrin vesicle coat (GO:0030125)|coated pit (GO:0005905)|intracellular (GO:0005622)|plasma membrane (GO:0005886)		p.P201P(1)		endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	9		Colorectal(325;0.000147)|Renal(390;0.00145)|Lung NSC(340;0.00215)|Breast(348;0.00224)|all_lung(284;0.00351)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0646)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0182)|COAD - Colon adenocarcinoma(227;1.13e-05)|BRCA - Breast invasive adenocarcinoma(304;4.13e-05)|Kidney(64;0.000181)|KIRC - Kidney renal clear cell carcinoma(64;0.00268)|STAD - Stomach adenocarcinoma(196;0.012)|READ - Rectum adenocarcinoma(331;0.0649)		CCCTGATCCCTCCCCCTGGGG	0.647																																						ENST00000337132.5																			1	Substitution - coding silent(1)	p.P201P(1)	prostate(1)	endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	9						c.(601-603)ccT>ccC		NECAP endocytosis associated 2							51.0	57.0	55.0					1																	16778446		2203	4300	6503	SO:0001819	synonymous_variant	55707				endocytosis|protein transport	clathrin vesicle coat|coated pit|plasma membrane		g.chr1:16778446T>C	AK021938	CCDS173.1, CCDS44066.1, CCDS44067.1	1p36.13	2008-02-05			ENSG00000157191	ENSG00000157191			25528	protein-coding gene	gene with protein product		611624				14555962, 15494011	Standard	NM_001145277		Approved	FLJ10420	uc001ayq.3	Q9NVZ3	OTTHUMG00000002313	ENST00000337132.5:c.603T>C	1.37:g.16778446T>C						NECAP2_ENST00000504551.2_Silent_p.P140P|NECAP2_ENST00000457722.2_Silent_p.P175P|NECAP2_ENST00000443980.2_Silent_p.P201P|NECAP2_ENST00000406746.1_Silent_p.P201P	p.P201P	NM_001145278.1|NM_018090.4	NP_001138750.1|NP_060560.1	Q9NVZ3	NECP2_HUMAN		UCEC - Uterine corpus endometrioid carcinoma (279;0.0182)|COAD - Colon adenocarcinoma(227;1.13e-05)|BRCA - Breast invasive adenocarcinoma(304;4.13e-05)|Kidney(64;0.000181)|KIRC - Kidney renal clear cell carcinoma(64;0.00268)|STAD - Stomach adenocarcinoma(196;0.012)|READ - Rectum adenocarcinoma(331;0.0649)	6	693	+		Colorectal(325;0.000147)|Renal(390;0.00145)|Lung NSC(340;0.00215)|Breast(348;0.00224)|all_lung(284;0.00351)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0646)	201					B4DY19|E9PGQ8|Q5VSU4|Q5VSU5|Q9H7L1|Q9H8L1	Silent	SNP	ENST00000337132.5	37	c.603T>C	CCDS173.1																																																																																				0.647	NECAP2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000006680.2	NM_018090		3	83	0	0	0	0.014758	0	3	83				
HERC5	51191	broad.mit.edu	37	4	89415467	89415467	+	Missense_Mutation	SNP	G	G	T			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr4:89415467G>T	ENST00000264350.3	+	18	2582	c.2429G>T	c.(2428-2430)aGt>aTt	p.S810I	HERC5_ENST00000508159.1_Missense_Mutation_p.S448I|AC083829.1_ENST00000408152.2_RNA	NM_016323.3	NP_057407.2	Q9UII4	HERC5_HUMAN	HECT and RLD domain containing E3 ubiquitin protein ligase 5	810	HECT. {ECO:0000255|PROSITE- ProRule:PRU00104}.				cytokine-mediated signaling pathway (GO:0019221)|defense response to virus (GO:0051607)|innate immune response (GO:0045087)|ISG15-protein conjugation (GO:0032020)|negative regulation of type I interferon production (GO:0032480)|protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0042787)|regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079)|regulation of defense response to virus (GO:0050688)	cytoplasm (GO:0005737)|cytosol (GO:0005829)|nucleus (GO:0005634)	ISG15 ligase activity (GO:0042296)|poly(A) RNA binding (GO:0044822)|ubiquitin-protein transferase activity (GO:0004842)	p.S810I(2)|p.S810T(1)		NS(2)|breast(3)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(11)|liver(2)|lung(17)|ovary(4)|prostate(1)|skin(4)	53		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000209)		AAAGAACTCAGTCCTGATTTG	0.383																																					Esophageal Squamous(39;887 1012 34045 50514)	ENST00000264350.3																			3	Substitution - Missense(3)	p.S810I(2)|p.S810T(1)	prostate(2)|lung(1)	NS(2)|breast(3)|cervix(1)|endometrium(5)|kidney(3)|large_intestine(11)|liver(2)|lung(17)|ovary(4)|prostate(1)|skin(4)	53						c.(2428-2430)aGt>aTt		HECT and RLD domain containing E3 ubiquitin protein ligase 5							72.0	74.0	73.0					4																	89415467		2203	4300	6503	SO:0001583	missense	51191				innate immune response|ISG15-protein conjugation|negative regulation of type I interferon production|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|regulation of cyclin-dependent protein kinase activity|regulation of defense response to virus|response to virus	cytosol|perinuclear region of cytoplasm	ISG15 ligase activity|protein binding|ubiquitin-protein ligase activity	g.chr4:89415467G>T	AB027289	CCDS3630.1	4q22.1-q23	2012-02-23	2012-02-23		ENSG00000138646	ENSG00000138646			24368	protein-coding gene	gene with protein product		608242	"""hect domain and RLD 5"""			10581175	Standard	NM_016323		Approved	CEB1	uc003hrt.4	Q9UII4	OTTHUMG00000130953	ENST00000264350.3:c.2429G>T	4.37:g.89415467G>T	ENSP00000264350:p.Ser810Ile					HERC5_ENST00000508159.1_Missense_Mutation_p.S448I	p.S810I	NM_016323.3	NP_057407.2	Q9UII4	HERC5_HUMAN		OV - Ovarian serous cystadenocarcinoma(123;0.000209)	18	2582	+		Hepatocellular(203;0.114)	810			HECT.		B2RTQ1|Q69G20	Missense_Mutation	SNP	ENST00000264350.3	37	c.2429G>T	CCDS3630.1	.	.	.	.	.	.	.	.	.	.	G	16.01	3.001327	0.54254	.	.	ENSG00000138646	ENST00000264350;ENST00000508159	T;T	0.58358	0.34;0.34	4.48	3.56	0.40772	HECT (4);	0.231893	0.32161	N	0.006488	T	0.67878	0.2940	M	0.87547	2.89	0.23314	N	0.997927	P	0.52061	0.95	P	0.60541	0.876	T	0.60801	-0.7191	10	0.72032	D	0.01	.	5.7944	0.18379	0.1046:0.1976:0.6977:0.0	.	810	Q9UII4	HERC5_HUMAN	I	810;448	ENSP00000264350:S810I;ENSP00000424129:S448I	ENSP00000264350:S810I	S	+	2	0	HERC5	89634490	0.000000	0.05858	1.000000	0.80357	0.948000	0.59901	0.443000	0.21644	2.479000	0.83701	0.491000	0.48974	AGT		0.383	HERC5-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000253554.2	NM_016323		3	60	1	0	0.004672	0.004672	0.00509673	3	60				
RABGAP1	23637	broad.mit.edu	37	9	125860018	125860018	+	Splice_Site	SNP	A	A	G			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr9:125860018A>G	ENST00000373647.4	+	22	2762		c.e22-1		RABGAP1_ENST00000373643.5_Splice_Site	NM_012197.3	NP_036329.3	Q9Y3P9	RBGP1_HUMAN	RAB GTPase activating protein 1						cell cycle (GO:0007049)|positive regulation of GTPase activity (GO:0043547)|regulation of GTP catabolic process (GO:0033124)	centrosome (GO:0005813)|cytosol (GO:0005829)|microtubule associated complex (GO:0005875)	DNA binding (GO:0003677)|GTPase activator activity (GO:0005096)|Rab GTPase activator activity (GO:0005097)|Rab GTPase binding (GO:0017137)|tubulin binding (GO:0015631)	p.?(2)		breast(3)|endometrium(3)|kidney(5)|large_intestine(8)|lung(11)|ovary(3)|prostate(4)|stomach(3)|upper_aerodigestive_tract(1)	41						TAAATGTTTCAGGCTGAGGAA	0.403																																						ENST00000373647.4																			2	Unknown(2)	p.?(2)	prostate(2)	breast(3)|endometrium(3)|kidney(5)|large_intestine(8)|lung(11)|ovary(3)|prostate(4)|stomach(3)|upper_aerodigestive_tract(1)	41						c.e22-1		RAB GTPase activating protein 1							100.0	101.0	101.0					9																	125860018		2203	4300	6503	SO:0001630	splice_region_variant	23637				cell cycle	centrosome|cytosol|microtubule associated complex	Rab GTPase activator activity|tubulin binding	g.chr9:125860018A>G	AJ011679	CCDS6848.2	9q34.11	2013-07-09			ENSG00000011454	ENSG00000011454			17155	protein-coding gene	gene with protein product	"""rab6 GTPase activating protein (GAP and centrosome-associated)"", ""TBC1 domain family, member 11"""	615882				10202141	Standard	NM_012197		Approved	GAPCenA, TBC1D11	uc011lzh.2	Q9Y3P9	OTTHUMG00000020633	ENST00000373647.4:c.2629-1A>G	9.37:g.125860018A>G						RABGAP1_ENST00000373643.5_Splice_Site		NM_012197.3	NP_036329.3	Q9Y3P9	RBGP1_HUMAN			22	2762	+								B9A6L2|Q05CW2|Q6ZMY1|Q9HA28|Q9P0E2|Q9UG67	Splice_Site	SNP	ENST00000373647.4	37		CCDS6848.2	.	.	.	.	.	.	.	.	.	.	A	21.4	4.143152	0.77888	.	.	ENSG00000011454	ENST00000373647;ENST00000373643	.	.	.	5.15	5.15	0.70609	.	.	.	.	.	.	.	.	.	.	.	0.80722	D	1	.	.	.	.	.	.	.	.	.	.	.	.	.	.	15.1426	0.72623	1.0:0.0:0.0:0.0	.	.	.	.	.	-1	.	.	.	+	.	.	RABGAP1	124899839	1.000000	0.71417	0.992000	0.48379	0.910000	0.53928	8.998000	0.93550	2.170000	0.68504	0.459000	0.35465	.		0.403	RABGAP1-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000053976.3	NM_012197	Intron	3	73	0	0	0	0.004672	0	3	73				
PHKA2	5256	broad.mit.edu	37	X	18929061	18929061	+	Missense_Mutation	SNP	G	G	A			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chrX:18929061G>A	ENST00000379942.4	-	20	2820	c.2155C>T	c.(2155-2157)Ccg>Tcg	p.P719S		NM_000292.2	NP_000283.1	P46019	KPB2_HUMAN	phosphorylase kinase, alpha 2 (liver)	719					carbohydrate metabolic process (GO:0005975)|cellular protein modification process (GO:0006464)|generation of precursor metabolites and energy (GO:0006091)|glucose metabolic process (GO:0006006)|glycogen catabolic process (GO:0005980)|protein phosphorylation (GO:0006468)|small molecule metabolic process (GO:0044281)	cytosol (GO:0005829)|phosphorylase kinase complex (GO:0005964)|plasma membrane (GO:0005886)	hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553)|phosphorylase kinase activity (GO:0004689)			NS(1)|biliary_tract(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(1)|large_intestine(12)|lung(23)|ovary(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	61	Hepatocellular(33;0.183)					ACTTTAGTCGGCAAAGTCATG	0.363																																						ENST00000379942.4																			0				NS(1)|biliary_tract(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(1)|large_intestine(12)|lung(23)|ovary(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	61						c.(2155-2157)Ccg>Tcg		phosphorylase kinase, alpha 2 (liver)							120.0	115.0	117.0					X																	18929061		2203	4300	6503	SO:0001583	missense	5256				glucose metabolic process|glycogen catabolic process	cytosol|phosphorylase kinase complex|plasma membrane	calmodulin binding|glucan 1,4-alpha-glucosidase activity|phosphorylase kinase activity	g.chrX:18929061G>A		CCDS14190.1	Xp22.2-p22.1	2009-07-10			ENSG00000044446	ENSG00000044446	2.7.11.19		8926	protein-coding gene	gene with protein product		300798		PHK, PYK		2387090	Standard	NM_000292		Approved		uc004cyv.4	P46019	OTTHUMG00000021222	ENST00000379942.4:c.2155C>T	X.37:g.18929061G>A	ENSP00000369274:p.Pro719Ser						p.P719S	NM_000292.2	NP_000283.1	P46019	KPB2_HUMAN			20	2820	-	Hepatocellular(33;0.183)		719					A8K1T1|Q6LAJ5|Q7Z6W0|Q96CR3|Q9UDA1	Missense_Mutation	SNP	ENST00000379942.4	37	c.2155C>T	CCDS14190.1	.	.	.	.	.	.	.	.	.	.	G	12.39	1.922393	0.33908	.	.	ENSG00000044446	ENST00000379942	D	0.90563	-2.69	5.75	5.75	0.90469	Glycoside hydrolase 15-related (1);	0.000000	0.85682	D	0.000000	D	0.90504	0.7025	L	0.60455	1.87	0.58432	D	0.999996	B	0.24576	0.106	B	0.36378	0.223	D	0.86944	0.2081	10	0.26408	T	0.33	-10.3521	17.078	0.86591	0.0:0.0:1.0:0.0	.	719	P46019	KPB2_HUMAN	S	719	ENSP00000369274:P719S	ENSP00000369274:P719S	P	-	1	0	PHKA2	18838982	1.000000	0.71417	0.999000	0.59377	0.465000	0.32709	6.010000	0.70753	2.412000	0.81896	0.600000	0.82982	CCG		0.363	PHKA2-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000055960.1	NM_000292		4	76	0	0	0	0.009096	0	4	76				
SLC2A6	11182	broad.mit.edu	37	9	136340607	136340607	+	Missense_Mutation	SNP	G	G	T			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr9:136340607G>T	ENST00000371899.4	-	5	766	c.689C>A	c.(688-690)gCc>gAc	p.A230D	SLC2A6_ENST00000371897.4_Missense_Mutation_p.A230D|SLC2A6_ENST00000485978.1_5'UTR	NM_017585.3	NP_060055.2	Q9UGQ3	GTR6_HUMAN	solute carrier family 2 (facilitated glucose transporter), member 6	230					glucose transport (GO:0015758)|transmembrane transport (GO:0055085)	integral component of membrane (GO:0016021)|membrane (GO:0016020)|plasma membrane (GO:0005886)	glucose transmembrane transporter activity (GO:0005355)	p.A230D(3)		cervix(1)|endometrium(1)|large_intestine(1)|lung(3)|prostate(3)|skin(1)	10				OV - Ovarian serous cystadenocarcinoma(145;8.47e-08)|Epithelial(140;9.37e-07)|all cancers(34;1.03e-05)		CGCCCGCAGGGCCTCTTCGTC	0.667																																						ENST00000371899.4																			3	Substitution - Missense(3)	p.A230D(3)	prostate(2)|lung(1)	cervix(1)|endometrium(1)|large_intestine(1)|lung(3)|prostate(3)|skin(1)	10						c.(688-690)gCc>gAc		solute carrier family 2 (facilitated glucose transporter), member 6							29.0	26.0	27.0					9																	136340607		2201	4298	6499	SO:0001583	missense	11182					integral to membrane|plasma membrane	D-glucose transmembrane transporter activity	g.chr9:136340607G>T	AJ011372	CCDS6975.1, CCDS48052.1	9q34	2013-05-22			ENSG00000160326	ENSG00000160326		"""Solute carriers"""	11011	protein-coding gene	gene with protein product		606813				10970791	Standard	NM_001145099		Approved	GLUT9, GLUT6, HSA011372	uc004cee.3	Q9UGQ3	OTTHUMG00000020874	ENST00000371899.4:c.689C>A	9.37:g.136340607G>T	ENSP00000360966:p.Ala230Asp					SLC2A6_ENST00000485978.1_5'UTR|SLC2A6_ENST00000371897.4_Missense_Mutation_p.A230D	p.A230D	NM_017585.3	NP_060055.2	Q9UGQ3	GTR6_HUMAN		OV - Ovarian serous cystadenocarcinoma(145;8.47e-08)|Epithelial(140;9.37e-07)|all cancers(34;1.03e-05)	5	766	-			230					A6NNU6|Q5SXD7|Q8NCC2	Missense_Mutation	SNP	ENST00000371899.4	37	c.689C>A	CCDS6975.1	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	.|.	G|G	27.9|27.9	4.870626|4.870626	0.91587|0.91587	.|.	.|.	ENSG00000160326|ENSG00000160326	ENST00000371897;ENST00000371899;ENST00000414172|ENST00000432868	D;D|D	0.83673|0.90620	-1.75;-1.75|-2.7	5.39|5.39	5.39|5.39	0.77823|0.77823	Major facilitator superfamily domain, general substrate transporter (1);Major facilitator superfamily domain (1);|.	0.000000|.	0.85682|.	D|.	0.000000|.	D|D	0.97062|0.97062	0.9040|0.9040	H|H	0.97077|0.97077	3.935|3.935	0.80722|0.80722	D|D	1|1	D;D|.	0.89917|.	1.0;1.0|.	D;D|.	0.97110|.	0.999;1.0|.	D|D	0.97265|0.97265	0.9907|0.9907	10|7	0.72032|0.41790	D|T	0.01|0.15	.|.	18.1313|18.1313	0.89602|0.89602	0.0:0.0:1.0:0.0|0.0:0.0:1.0:0.0	.|.	230;230|.	Q9UGQ3-2;Q9UGQ3|.	.;GTR6_HUMAN|.	D|T	230;230;120|192	ENSP00000360964:A230D;ENSP00000360966:A230D|ENSP00000405124:P192T	ENSP00000360964:A230D|ENSP00000405124:P192T	A|P	-|-	2|1	0|0	SLC2A6|SLC2A6	135330428|135330428	1.000000|1.000000	0.71417|0.71417	0.950000|0.950000	0.38849|0.38849	0.835000|0.835000	0.47333|0.47333	9.238000|9.238000	0.95380|0.95380	2.515000|2.515000	0.84797|0.84797	0.561000|0.561000	0.74099|0.74099	GCC|CCC		0.667	SLC2A6-001	KNOWN	basic|appris_principal|CCDS	protein_coding	protein_coding	OTTHUMT00000054909.1	NM_017585		5	27	1	0	1.23904e-05	0.014758	1.48685e-05	5	27				
IL1RAP	3556	broad.mit.edu	37	3	190345113	190345113	+	Splice_Site	SNP	A	A	G			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr3:190345113A>G	ENST00000412504.2	+	7	1029	c.777A>G	c.(775-777)ggA>ggG	p.G259G	IL1RAP_ENST00000439062.1_Splice_Site_p.G259G|IL1RAP_ENST00000443369.2_Splice_Site_p.G259G|IL1RAP_ENST00000447382.1_Splice_Site_p.G259G|IL1RAP_ENST00000072516.3_Splice_Site_p.G259G|IL1RAP_ENST00000317757.3_Splice_Site_p.G259G|IL1RAP_ENST00000422940.1_Splice_Site_p.G259G|IL1RAP_ENST00000422485.1_Splice_Site_p.G259G|IL1RAP_ENST00000434491.1_Splice_Site_p.G118G			Q9NPH3	IL1AP_HUMAN	interleukin 1 receptor accessory protein	259	Ig-like C2-type 3.				immune response (GO:0006955)|inflammatory response (GO:0006954)|interleukin-2 biosynthetic process (GO:0042094)|protein complex assembly (GO:0006461)	extracellular region (GO:0005576)|integral component of plasma membrane (GO:0005887)|membrane (GO:0016020)|plasma membrane (GO:0005886)	interleukin-1 receptor activity (GO:0004908)|signal transducer activity (GO:0004871)	p.G259G(2)		NS(1)|breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(1)|lung(8)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	20	all_cancers(143;3.61e-10)|Ovarian(172;0.0733)|Breast(254;0.21)		Lung(62;1.95e-06)|LUSC - Lung squamous cell carcinoma(58;2.05e-06)	GBM - Glioblastoma multiforme(93;0.00851)		tttttTCAGGAGAGGAGCTAC	0.323																																						ENST00000412504.2																			2	Substitution - coding silent(2)	p.G259G(2)	prostate(2)	NS(1)|breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(1)|lung(8)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	20						c.e7-1		interleukin 1 receptor accessory protein							92.0	85.0	88.0					3																	190345113		2203	4300	6503	SO:0001630	splice_region_variant	0				inflammatory response|innate immune response|protein complex assembly	extracellular region|integral to plasma membrane		g.chr3:190345113A>G	AB006537	CCDS3298.1, CCDS46982.1, CCDS54696.1	3q28	2013-01-11			ENSG00000196083	ENSG00000196083		"""Interleukins and interleukin receptors"", ""Immunoglobulin superfamily / Immunoglobulin-like domain containing"""	5995	protein-coding gene	gene with protein product		602626				9479509, 9065432	Standard	NM_002182		Approved	IL-1RAcP, IL1R3, C3orf13	uc003fsq.3	Q9NPH3	OTTHUMG00000156211	ENST00000412504.2:c.776-1A>G	3.37:g.190345113A>G						IL1RAP_ENST00000439062.1_Splice_Site_p.G259_splice|IL1RAP_ENST00000447382.1_Splice_Site_p.G259_splice|IL1RAP_ENST00000317757.3_Splice_Site_p.G259_splice|IL1RAP_ENST00000422940.1_Splice_Site_p.G259_splice|IL1RAP_ENST00000443369.2_Splice_Site_p.G259_splice|IL1RAP_ENST00000072516.3_Splice_Site_p.G259_splice|IL1RAP_ENST00000422485.1_Splice_Site_p.G259_splice|IL1RAP_ENST00000434491.1_Splice_Site_p.G118_splice	p.G259_splice			Q9NPH3	IL1AP_HUMAN	Lung(62;1.95e-06)|LUSC - Lung squamous cell carcinoma(58;2.05e-06)	GBM - Glioblastoma multiforme(93;0.00851)	7	1029	+	all_cancers(143;3.61e-10)|Ovarian(172;0.0733)|Breast(254;0.21)		259			Ig-like C2-type 3.		B1NLD0|D3DNW0|O14915|Q86WJ7	Splice_Site	SNP	ENST00000412504.2	37	c.775_splice	CCDS3298.1	.	.	.	.	.	.	.	.	.	.	A	8.449	0.852713	0.17106	.	.	ENSG00000196083	ENST00000412080	.	.	.	5.97	-0.0244	0.13939	.	.	.	.	.	T	0.51805	0.1696	.	.	.	0.80722	D	1	.	.	.	.	.	.	T	0.40813	-0.9543	4	.	.	.	.	6.3878	0.21569	0.4562:0.0:0.0745:0.4693	.	.	.	.	G	96	.	.	E	+	2	0	IL1RAP	191827807	0.990000	0.36364	1.000000	0.80357	0.506000	0.33950	0.049000	0.14099	0.123000	0.18342	-1.581000	0.00855	GAG		0.323	IL1RAP-201	KNOWN	basic|appris_candidate|CCDS	protein_coding	protein_coding	OTTHUMT00000343497.1		Silent	3	44	0	0	0	0.014758	0	3	44				
MIR646HG	284757	broad.mit.edu	37	20	58889825	58889826	+	lincRNA	INS	-	-	CCAT			TCGA-G9-6370-01A-11D-1786-08	TCGA-G9-6370-10A-01D-1786-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9689cb33-8ac9-4ee5-800d-3900769988af	8b44f615-8f5d-4c2d-8c8b-8d48de8db586	g.chr20:58889825_58889826insCCAT	ENST00000432910.1	+	0	332					NR_046099.1																						catccatcctcccatcctccca	0.569																																						ENST00000432910.1																			0																																																			0							g.chr20:58889825_58889826insCCAT																													20.37:g.58889826_58889829dupCCAT								NR_046099.1						0	332	+									RNA	INS	ENST00000432910.1	37																																																																																						0.569	RP5-1043L13.1-001	KNOWN	basic	lincRNA	lincRNA	OTTHUMT00000079947.1			2	4						2	4	---	---	---	---
