Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CROCCP2	84809	broad.mit.edu	37	1	16945409	16945409	+	RNA	SNP	T	T	A	rs13566		TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr1:16945409T>A	ENST00000412962.1	-	0	2110																											GCGGGATAGCTCGGTGGAGAG	0.612000													7	56					0	0	8.12818e-05	0	0
FRG1B	284802	broad.mit.edu	37	20	29628225	29628225	+	Splice_Site	SNP	A	A	G			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr20:29628225A>G	ENST00000278882.3	+	6	608		c.e6-1		FRG1B_ENST00000439954.2_Splice_Site|FRG1B_ENST00000358464.4_Splice_Site																endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						TGTTTCACTTAGGGGAAAATG	0.358000													4	45					0	0	2.56e-06	0	0
SLC6A10P	386757	broad.mit.edu	37	16	32890622	32890622	+	RNA	SNP	T	T	G			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr16:32890622T>G	ENST00000330048.5	-	0	3176					NR_003083.2																						CGTTGGTGTTTTTGTAGACCA	0.617000													3	20					0	0	6.4e-05	0	0
EP400	57634	broad.mit.edu	37	12	132547093	132547093	+	Silent	SNP	A	A	G	rs60608267	by1000genomes	TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr12:132547093A>G	ENST00000333577.4	+	48	8398	c.8289A>G	c.(8287-8289)caA>caG	p.Q2763Q	EP400_ENST00000330386.6_Silent_p.Q2646Q|EP400_ENST00000332482.4_Silent_p.Q2690Q|EP400_ENST00000389561.2_Silent_p.Q2727Q|EP400_ENST00000389562.2_Silent_p.Q2726Q			Q96L91	EP400_HUMAN	E1A binding protein p400	2763	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity	p.Q2726Q(9)		NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcaacaacagcagcagc	0.567000													6	77					0	0	3.59834e-05	0	0
WHAMMP3	339005	broad.mit.edu	37	15	23205094	23205094	+	RNA	SNP	G	G	A			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr15:23205094G>A	ENST00000400153.2	-	0	760					NR_003521.1																						AGTACTGGAAGAACGTGGTTG	0.373000													4	23					0	0	2.56e-06	0	0
KIAA0907	22889	broad.mit.edu	37	1	155886422	155886423	+	Frame_Shift_Del	DEL	CT	CT	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr1:155886422_155886423delCT	ENST00000368320.3	-	12	1571_1572	c.1546_1547delAG	c.(1546-1548)gfs	p.R516fs	KIAA0907_ENST00000368321.3_Frame_Shift_Del_p.R516fs			Q7Z7F0	K0907_HUMAN	KIAA0907	516								p.R516fs*21(1)		breast(1)|endometrium(2)|kidney(1)|large_intestine(4)|liver(1)|lung(11)|urinary_tract(1)	21	Hepatocellular(266;0.133)|all_hematologic(923;0.145)|all_neural(408;0.195)		OV - Ovarian serous cystadenocarcinoma(3;8.82e-06)			TTACCTGTCCCTCTCTCTCTCT	0.396													7	361	---	---	---	---					
TTN	7273	broad.mit.edu	37	2	179588388	179588388	+	Frame_Shift_Del	DEL	C	C	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr2:179588388delC	ENST00000589042.1	-	74	21663	c.21439delG	c.(21439-21441)aafs	p.E7147fs	TTN_ENST00000359218.5_Intron|RP11-171I2.1_ENST00000590024.1_RNA|TTN_ENST00000342175.6_Intron|TTN_ENST00000342992.6_Frame_Shift_Del_p.E5903fs|TTN_ENST00000460472.2_Intron|TTN-AS1_ENST00000585451.1_RNA|TTN_ENST00000591111.1_Frame_Shift_Del_p.E6830fs	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	6830	Ig-like 53.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			GGTAGTACTTCCAAAGGTTCA	0.403													2	4	---	---	---	---					
TRERF1	55809	broad.mit.edu	37	6	42196333	42196333	+	Frame_Shift_Del	DEL	T	T	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr6:42196333delT	ENST00000541110.1	-	18	3981	c.3413delA	c.(3412-3414)agfs	p.K1138fs	TRERF1_ENST00000340840.2_Frame_Shift_Del_p.K1047fs|TRERF1_ENST00000372922.4_Frame_Shift_Del_p.K1118fs|TRERF1_ENST00000354325.2_Frame_Shift_Del_p.K1035fs|TRERF1_ENST00000372917.4_Frame_Shift_Del_p.K1047fs			Q96PN7	TREF1_HUMAN	transcriptional regulating factor 1	1118	Interacts with CREBBP.				cholesterol catabolic process|homeostatic process|multicellular organismal development|positive regulation of transcription, DNA-dependent|regulation of hormone biosynthetic process|steroid biosynthetic process	nucleus	DNA bending activity|ligand-dependent nuclear receptor transcription coactivator activity|RNA polymerase II transcription cofactor activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|zinc ion binding			breast(1)|central_nervous_system(2)|endometrium(7)|kidney(1)|large_intestine(12)|lung(13)|ovary(3)|pancreas(1)|skin(3)|urinary_tract(2)	45	Colorectal(47;0.196)		Colorectal(64;0.00062)|COAD - Colon adenocarcinoma(64;0.00152)			CTTCTGAGCCTTTTGCCTCTG	0.542													8	826	---	---	---	---					
NUTM2F	54754	broad.mit.edu	37	9	97080945	97080947	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr9:97080945_97080947delAGA	ENST00000253262.4	-	7	2091_2093	c.2071_2073delTCT	c.(2071-2073)del	p.S691del	NUTM2F_ENST00000335456.7_Intron|NUTM2F_ENST00000341207.4_In_Frame_Del_p.S676del	NM_017561.1	NP_060031.1			NUT family member 2F									p.S557delS(1)									TGCTGGCAGGAGAAGGTGATGGG	0.611													6	5	---	---	---	---					
HNF1A	6927	broad.mit.edu	37	12	121432115	121432115	+	Frame_Shift_Del	DEL	G	G	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr12:121432115delG	ENST00000257555.6	+	4	1088	c.862delG	c.(862-864)ggfs	p.G288fs	HNF1A_ENST00000538626.1_Intron|HNF1A_ENST00000402929.1_Frame_Shift_Del_p.G288fs|HNF1A_ENST00000400024.2_Frame_Shift_Del_p.G288fs|HNF1A_ENST00000544413.1_Frame_Shift_Del_p.G288fs|HNF1A_ENST00000541395.1_Frame_Shift_Del_p.G288fs|HNF1A_ENST00000543427.1_Frame_Shift_Del_p.G171fs			P20823	HNF1A_HUMAN	HNF1 homeobox A	288					glucose homeostasis|glucose import|insulin secretion|positive regulation of transcription initiation from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|renal glucose absorption	cytoplasm|nucleus|protein complex	DNA binding|protein dimerization activity|protein heterodimerization activity|protein homodimerization activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding			breast(3)|central_nervous_system(2)|cervix(1)|endometrium(8)|large_intestine(19)|liver(175)|lung(9)|ovary(2)|prostate(1)|urinary_tract(1)	221	all_neural(191;0.0684)|Medulloblastoma(191;0.0922)					CACGTACAGCGGGCCCCCCCC	0.672									Hepatic Adenoma, Familial Clustering of				10	272	---	---	---	---					
CHD9	80205	broad.mit.edu	37	16	53191095	53191095	+	Frame_Shift_Del	DEL	T	T	-			TCGA-EE-A2GK-06A-11D-A196-08	TCGA-EE-A2GK-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	9d39d79f-ebea-463b-af46-7a59ef21ed1f	76a32d10-71f6-444c-93de-e96ae7e4ffdb	g.chr16:53191095delT	ENST00000566029.1	+	2	1303	c.1094delT	c.(1093-1095)gtfs	p.V365fs	CHD9_ENST00000398510.3_Frame_Shift_Del_p.V365fs|CHD9_ENST00000447540.1_Frame_Shift_Del_p.V365fs|CHD9_ENST00000564845.1_Frame_Shift_Del_p.V365fs			Q3L8U1	CHD9_HUMAN	chromodomain helicase DNA binding protein 9	365					cellular lipid metabolic process|chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleoplasm	ATP binding|DNA binding|helicase activity|protein binding			NS(1)|breast(4)|central_nervous_system(1)|endometrium(5)|kidney(6)|large_intestine(21)|lung(32)|ovary(2)|prostate(2)|skin(2)|stomach(1)|urinary_tract(1)	78		all_cancers(37;0.0212)				CCAGATCCTGTTGACTCAGGA	0.343													2	4	---	---	---	---					
