Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CNGB1	1258	broad.mit.edu	37	16	57993834	57993834	+	Missense_Mutation	SNP	T	T	C			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr16:57993834T>C	ENST00000564448.1	-	10	761	c.701A>G	c.(700-702)cAg>cGg	p.Q234R	CNGB1_ENST00000251102.8_Missense_Mutation_p.Q240R|CNGB1_ENST00000311183.4_Missense_Mutation_p.Q240R			Q14028	CNGB1_HUMAN	cyclic nucleotide gated channel beta 1	240	Pro-rich.				sensory perception of smell	intracellular cyclic nucleotide activated cation channel complex	cAMP binding|intracellular cAMP activated cation channel activity			breast(7)|cervix(2)|endometrium(4)|kidney(2)|large_intestine(11)|liver(1)|lung(12)|ovary(1)|pancreas(1)|prostate(2)|skin(5)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	54						GGTCTGGGCCTGGGAGCCGGG	0.701000													3	22					0	0	1	0	0
KRTAP4-11	653240	broad.mit.edu	37	17	39274170	39274170	+	Missense_Mutation	SNP	G	G	T			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr17:39274170G>T	ENST00000391413.2	-	1	436	c.398C>A	c.(397-399)aCc>aAc	p.T133N		NM_033059.3	NP_149048.2	Q9BYQ6	KR411_HUMAN	keratin associated protein 4-11	133	27 X 5 AA repeats of C-C-[GIKRQVHEL]- [SPTR]-[STVQRMC].					keratin filament				endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|lung(8)|prostate(5)|skin(1)	33		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000371)			gtggcagcaggtgggctggca	0.672000													6	39					7.48243e-07	7.83873e-07	1	1	0
ZNF733P	0	broad.mit.edu	37	7	62752443	62752443	+	RNA	SNP	G	G	C			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr7:62752443G>C	ENST00000331425.6	-	0	992					NR_003952.1																						CTTATGTCTAGTAAGGTTTGA	0.438000													3	16					0	0	1	0	0
ME1	4199	broad.mit.edu	37	6	83963383	83963383	+	Missense_Mutation	SNP	C	C	T	rs142401926		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr6:83963383C>T	ENST00000369705.3	-	7	895	c.779G>A	c.(778-780)cGa>cAa	p.R260Q	ME1_ENST00000543031.1_Missense_Mutation_p.R185Q|ME1_ENST00000541327.1_Missense_Mutation_p.R94Q	NM_002395.4	NP_002386.1	P48163	MAOX_HUMAN	malic enzyme 1, NADP(+)-dependent, cytosolic	260					carbohydrate metabolic process|cellular lipid metabolic process|malate metabolic process|NADP biosynthetic process|response to carbohydrate stimulus|response to hormone stimulus	cytosol	ADP binding|electron carrier activity|malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity|manganese ion binding|NAD binding|NADP binding			NS(2)|breast(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(7)|ovary(2)|prostate(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	36		all_cancers(76;1.28e-06)|Acute lymphoblastic leukemia(125;5.03e-07)|all_hematologic(105;0.000238)|all_epithelial(107;0.00218)		BRCA - Breast invasive adenocarcinoma(397;0.0641)	NADH(DB00157)	ATACTGGTTTCGATACTTGTT	0.318000													3	28					0	0	1	0	0
TRAV6	0	broad.mit.edu	37	14	22236756	22236756	+	RNA	SNP	G	G	C	rs766738	by1000genomes	TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr14:22236756G>C	ENST00000390428.3	+	0	28																											GGCTGAGAAGGCTGGGTCTAC	0.473000													8	180					0	0	1	0	0
SRPK2	6733	broad.mit.edu	37	7	104844169	104844169	+	Silent	SNP	C	C	T			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr7:104844169C>T	ENST00000357311.3	-	2	273	c.102G>A	c.(100-102)ccG>ccA	p.P34P	SRPK2_ENST00000489828.1_Silent_p.P34P|SRPK2_ENST00000393651.3_Silent_p.P45P	NM_001278273.1|NM_182691.1	NP_001265202.1|NP_872633.1	P78362	SRPK2_HUMAN	SRSF protein kinase 2	34					angiogenesis|cell differentiation|intracellular protein kinase cascade|negative regulation of viral genome replication|nuclear speck organization|positive regulation of cell cycle|positive regulation of cell proliferation|positive regulation of gene expression|positive regulation of neuron apoptosis|positive regulation of viral genome replication|spliceosome assembly	cytoplasm|nucleolus	14-3-3 protein binding|ATP binding|magnesium ion binding|protein serine/threonine kinase activity			NS(1)|breast(1)|central_nervous_system(3)|endometrium(1)|kidney(11)|large_intestine(6)|lung(4)|ovary(3)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)	35						GCAAAggtggcggtggtggtg	0.557000													4	55					0	0	1	0	0
RAD17	5884	broad.mit.edu	37	5	68692367	68692367	+	Missense_Mutation	SNP	T	T	A			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr5:68692367T>A	ENST00000509734.1	+	15	2277	c.1599T>A	c.(1597-1599)aaT>aaA	p.N533K	RAD17_ENST00000282891.6_Missense_Mutation_p.N436K|RAD17_ENST00000361732.2_Missense_Mutation_p.N522K|RAD17_ENST00000305138.4_Missense_Mutation_p.N522K|RAD17_ENST00000345306.6_Missense_Mutation_p.N522K|RAD17_ENST00000380774.3_Missense_Mutation_p.N533K|RAD17_ENST00000504177.1_Intron|RAD17_ENST00000354312.3_Missense_Mutation_p.N522K|RAD17_ENST00000354868.5_Missense_Mutation_p.N522K|RAD17_ENST00000521422.1_Missense_Mutation_p.N357K|RAD17_ENST00000358030.2_Missense_Mutation_p.N357K			O75943	RAD17_HUMAN	RAD17 homolog (S. pombe)	533	Interaction with MCM7.				cell cycle|DNA damage checkpoint|DNA repair|DNA replication|DNA replication checkpoint|mitotic cell cycle checkpoint|negative regulation of DNA replication|regulation of phosphorylation	nucleoplasm	ATP binding|nucleoside-triphosphatase activity|protein binding						Lung NSC(167;5.19e-05)|Prostate(74;0.0143)|Ovarian(174;0.0448)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;9.36e-57)|Epithelial(20;1.21e-52)|all cancers(19;3.34e-48)|Lung(70;0.0183)		TTCTAATAAATAAAAAGGTAA	0.338000								Other conserved DNA damage response genes					6	4					0	0	1	0	0
C6orf15	29113	broad.mit.edu	37	6	31079317	31079317	+	Silent	SNP	C	C	T	rs147375238	byFrequency	TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr6:31079317C>T	ENST00000259870.3	-	2	822	c.819G>A	c.(817-819)ggG>ggA	p.G273G		NM_014070.2	NP_054789.2	Q6UXA7	CF015_HUMAN	chromosome 6 open reading frame 15	273	Gly-rich.									endometrium(3)|large_intestine(2)|lung(9)|prostate(1)|skin(1)|stomach(1)	17						GATTAATATTCCCCCAGCTGC	0.498000													18	83					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				16	29					0	0	1	0	0
ZNF860	344787	broad.mit.edu	37	3	32030998	32030998	+	Nonsense_Mutation	SNP	C	C	T	rs4639011	by1000genomes	TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr3:32030998C>T	ENST00000360311.4	+	2	976	c.427C>T	c.(427-429)Cga>Tga	p.R143*		NM_001137674.2	NP_001131146.2	A6NHJ4	ZN860_HUMAN	zinc finger protein 860	143					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(3)|lung(4)|ovary(1)	8						CAGATATGATCGAAGGCATCC	0.403000													5	63					0	0	1	0	0
RP11-798G7.5	0	broad.mit.edu	37	17	43587497	43587497	+	RNA	SNP	T	T	G			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr17:43587497T>G	ENST00000253803.2	+	0	267				LRRC37A4P_ENST00000579913.1_RNA																							ttgaacctggtaagtggaggt	0.483000													4	45					0	0	1	0	0
TRIM33	51592	broad.mit.edu	37	1	114968115	114968116	+	Frame_Shift_Ins	INS	-	-	T			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr1:114968115_114968116insT	ENST00000358465.2	-	9	1733_1734	c.1650_1651insA	c.(1648-1653)acaacafs	p.T551fs	TRIM33_ENST00000369543.2_Frame_Shift_Ins_p.T551fs|TRIM33_ENST00000450349.2_Frame_Shift_Ins_p.T159fs	NM_015906.3	NP_056990.3	Q9UPN9	TRI33_HUMAN	tripartite motif containing 33	551					negative regulation of BMP signaling pathway|negative regulation of transcription, DNA-dependent|protein ubiquitination|regulation of transforming growth factor beta receptor signaling pathway|transcription, DNA-dependent	nucleus	co-SMAD binding|DNA binding|ligase activity|R-SMAD binding|zinc ion binding			breast(2)|central_nervous_system(5)|cervix(1)|endometrium(7)|kidney(2)|large_intestine(10)|lung(14)|ovary(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	48	all_epithelial(7;0.000132)|all_lung(7;0.00106)|Lung SC(450;0.184)	all_cancers(81;3.03e-08)|all_epithelial(167;3.24e-08)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GGATGCTGTTGTGTTGTTGTTG	0.426			T	RET	papillary thyroid								7	296	---	---	---	---					
SORBS2	8470	broad.mit.edu	37	4	186544620	186544622	+	In_Frame_Del	DEL	GGT	GGT	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr4:186544620_186544622delGGT	ENST00000431808.1	-	14	2512_2514	c.1949_1951delACC	c.(1948-1953)cgc>c	p.HR650del	SORBS2_ENST00000393528.3_Intron|SORBS2_ENST00000355634.5_In_Frame_Del_p.HR750del|SORBS2_ENST00000319471.9_Intron|SORBS2_ENST00000284776.7_In_Frame_Del_p.HR650del|SORBS2_ENST00000498125.1_Intron|SORBS2_ENST00000437304.2_Intron|SORBS2_ENST00000418609.1_In_Frame_Del_p.HR554del|SORBS2_ENST00000449407.2_Intron|SORBS2_ENST00000448662.2_Intron			O94875	SRBS2_HUMAN	sorbin and SH3 domain containing 2	650	His-rich.					actin cytoskeleton|nucleus|perinuclear region of cytoplasm|Z disc	cytoskeletal adaptor activity|structural constituent of cytoskeleton|structural constituent of muscle|zinc ion binding			endometrium(7)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(9)|lung(21)|ovary(2)|prostate(2)|skin(4)|urinary_tract(1)	53		all_cancers(14;4.27e-52)|all_epithelial(14;6.58e-39)|all_lung(41;1.42e-13)|Lung NSC(41;3.73e-13)|Melanoma(20;1.91e-06)|Colorectal(36;0.00692)|Hepatocellular(41;0.00826)|Renal(120;0.00994)|Prostate(90;0.0101)|all_hematologic(60;0.0174)|all_neural(102;0.244)		OV - Ovarian serous cystadenocarcinoma(60;1.54e-09)|BRCA - Breast invasive adenocarcinoma(30;0.000232)|GBM - Glioblastoma multiforme(59;0.000385)|STAD - Stomach adenocarcinoma(60;0.00109)|LUSC - Lung squamous cell carcinoma(40;0.0205)		ATGAggtggcggtggtggtggtg	0.522													8	185	---	---	---	---					
CTC-338M12.4	0	broad.mit.edu	37	5	180699086	180699086	+	RNA	DEL	G	G	-	rs149736603		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr5:180699086delG	ENST00000511331.1	+	0	918				CTC-338M12.3_ENST00000507434.1_RNA																							CTTTCCATCAGAAAAAAAAAA	0.408													3	3	---	---	---	---					
CTC-338M12.9	0	broad.mit.edu	37	5	180708776	180708777	+	RNA	INS	-	-	G	rs140221514		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr5:180708776_180708777insG	ENST00000412295.2	+	0	238																											gggcggtaggagggggctggag	0.728													10	12	---	---	---	---					
TCP11	6954	broad.mit.edu	37	6	35108990	35108990	+	Frame_Shift_Del	DEL	C	C	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr6:35108990delC	ENST00000311875.5	-	1	434	c.17delG	c.(16-18)gafs	p.G8fs	TCP11_ENST00000412155.2_Frame_Shift_Del_p.G9fs|TCP11_ENST00000373979.2_5'UTR|TCP11_ENST00000418521.2_Intron|TCP11_ENST00000510465.1_5'UTR|TCP11_ENST00000444780.2_Frame_Shift_Del_p.G8fs|TCP11_ENST00000244645.3_5'UTR|TCP11_ENST00000373974.4_Frame_Shift_Del_p.G8fs			Q8WWU5	TCP11_HUMAN	t-complex 11, testis-specific	0					cell differentiation|multicellular organismal development|spermatogenesis	integral to membrane		p.G6fs*56(1)		breast(1)|kidney(5)|large_intestine(3)|lung(10)|ovary(3)|prostate(1)|skin(4)	27						ACCTCCTCCTCCCCCGCCGCG	0.781													5	3	---	---	---	---					
MEPCE	56257	broad.mit.edu	37	7	100028823	100028825	+	In_Frame_Del	DEL	CCA	CCA	-	rs71555278		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr7:100028823_100028825delCCA	ENST00000310512.2	+	1	1570_1572	c.1182_1184delCCA	c.(1180-1185)cgc>cg	p.RH394del	MEPCE_ENST00000414441.1_5'UTR	NM_019606.5	NP_062552.2	Q7L2J0	MEPCE_HUMAN	methylphosphate capping enzyme	394							methyltransferase activity			breast(1)|endometrium(2)|kidney(1)|large_intestine(3)|liver(2)|lung(9)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)	24	Lung NSC(181;0.0181)|all_lung(186;0.0284)|Esophageal squamous(72;0.0439)					GGGGAGGCCGCCACCACCACCAC	0.581													7	187	---	---	---	---					
TRBV7-7	0	broad.mit.edu	37	7	142120209	142120210	+	RNA	DEL	TG	TG	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr7:142120209_142120210delTG	ENST00000390377.1	-	0	49																											cagacacacatgcatacacaca	0.436													9	144	---	---	---	---					
FAM66B	0	broad.mit.edu	37	8	7196263	7196264	+	RNA	DEL	AC	AC	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr8:7196263_7196264delAC	ENST00000606573.1	-	0	703																											ACTGAGGGGTacacacacacac	0.500													4	8	---	---	---	---					
ASTN2	23245	broad.mit.edu	37	9	119976989	119976991	+	In_Frame_Del	DEL	CAG	CAG	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr9:119976989_119976991delCAG	ENST00000313400.4	-	3	761_763	c.661_663delCTG	c.(661-663)del	p.L221del	ASTN2_ENST00000361209.2_In_Frame_Del_p.L221del|ASTN2_ENST00000373996.3_In_Frame_Del_p.L221del|ASTN2_ENST00000361477.3_5'UTR			O75129	ASTN2_HUMAN	astrotactin 2	221						integral to membrane				breast(3)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(21)|lung(45)|ovary(4)|pancreas(2)|prostate(2)|skin(9)|stomach(1)|urinary_tract(1)	102						CGGTGAACACCAGCAGCAGCAGC	0.601													7	125	---	---	---	---					
NEURL	0	broad.mit.edu	37	10	105344609	105344610	+	Frame_Shift_Del	DEL	GC	GC	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr10:105344609_105344610delGC	ENST00000369780.4	+	4	1375_1376	c.966_967delGC	c.(964-969)gagcfs	p.ER322fs	NEURL_ENST00000369777.2_Frame_Shift_Del_p.ER305fs	NM_004210.4	NP_004201.3	O76050	NEU1A_HUMAN		322	NHR 2.				nervous system development	perinuclear region of cytoplasm	zinc ion binding			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(1)|lung(4)|ovary(2)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	17				Epithelial(162;2.12e-09)|all cancers(201;6.99e-08)|BRCA - Breast invasive adenocarcinoma(275;0.125)		GGCGCGACGAGCGCGCGCTCGT	0.752													2	4	---	---	---	---					
SPON1	10418	broad.mit.edu	37	11	14063263	14063263	+	RNA	DEL	A	A	-	rs113227652		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr11:14063263delA	ENST00000310358.7	+	0	1017							Q9HCB6	SPON1_HUMAN	spondin 1, extracellular matrix protein						cell adhesion	extracellular space|proteinaceous extracellular matrix	protein binding			NS(1)|endometrium(1)|large_intestine(5)|lung(11)|prostate(2)|upper_aerodigestive_tract(1)	21				Epithelial(150;0.00898)		GATTGCAGGGAAAAAAAAAAA	0.423													9	39	---	---	---	---					
LPCAT3	10162	broad.mit.edu	37	12	7092661	7092661	+	Frame_Shift_Del	DEL	T	T	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr12:7092661delT	ENST00000261407.4	-	2	276	c.191delA	c.(190-192)tcfs	p.Y64fs	U47924.19_ENST00000564245.1_RNA	NM_005768.5	NP_005759.4	Q6P1A2	MBOA5_HUMAN	lysophosphatidylcholine acyltransferase 3	64					phospholipid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	1-acylglycerophosphocholine O-acyltransferase activity			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(2)|lung(4)|ovary(1)|skin(2)	17						GGTCTCCTTGTAGAAAAGGTA	0.418													7	164	---	---	---	---					
ABCA17P	0	broad.mit.edu	37	16	2475097	2475098	+	RNA	DEL	TC	TC	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr16:2475097_2475098delTC	ENST00000469908.1	+	0	3047					NR_003574.1																						GGTAActctgtctctctctctc	0.559													4	9	---	---	---	---					
AFG3L1P	0	broad.mit.edu	37	16	90053806	90053806	+	RNA	DEL	G	G	-			TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr16:90053806delG	ENST00000437774.1	+	0	731					NR_003226.1																						aggtggaggaggtggaggagg	0.642													2	4	---	---	---	---					
KRTAP10-6	386674	broad.mit.edu	37	21	46012219	46012220	+	In_Frame_Ins	INS	-	-	GGGGCGCAGCAGCTG	rs71199613		TCGA-EL-A3ZG-01A-11D-A23M-08	TCGA-EL-A3ZG-11A-13D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	e7706fa4-0ec2-4c1f-b0c5-d4efff97cccc	593d2302-87c2-48e3-b9a1-54511d86c105	g.chr21:46012219_46012220insGGGGCGCAGCAGCTG	ENST00000400368.1	-	1	166_167	c.146_147insCAGCTGCTGCGCCCC	c.(145-147)cgc>cCAGCTGCTGCGCCCCgc	p.48_49insPAAAP	TSPEAR_ENST00000323084.4_Intron	NM_198688.2	NP_941961.2	P60371	KR106_HUMAN	keratin associated protein 10-6	48	29 X 5 AA repeats of C-C-X(3).					keratin filament				endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(3)|lung(6)|prostate(3)|skin(1)|stomach(1)|urinary_tract(1)	23						GGCAGGGGGCCGGGGCGCAGCA	0.688													7	101	---	---	---	---					
