Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MGAT2	4247	broad.mit.edu	37	14	50088451	50088451	+	Missense_Mutation	SNP	C	C	G			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr14:50088451C>G	ENST00000305386.2	+	1	963	c.465C>G	c.(463-465)ttC>ttG	p.F155L	RP11-649E7.5_ENST00000555043.1_RNA	NM_002408.3	NP_002399.1	Q10469	MGAT2_HUMAN	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	155					oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	Golgi membrane|Golgi stack|integral to membrane|membrane fraction	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity			cervix(1)|endometrium(3)|large_intestine(1)|lung(6)	11	all_epithelial(31;0.0021)|Breast(41;0.0124)					GCCATGACTTCTGGTCGACCG	0.512000													3	71					0	0	1	0	0
PITPNA	5306	broad.mit.edu	37	17	1456343	1456343	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr17:1456343T>C	ENST00000313486.7	-	3	407	c.152A>G	c.(151-153)gAc>gGc	p.D51G	PITPNA_ENST00000539476.1_Missense_Mutation_p.D51G	NM_006224.3	NP_006215.1	Q00169	PIPNA_HUMAN	phosphatidylinositol transfer protein, alpha	51					axon guidance|lipid metabolic process|visual perception	cytoplasm	phosphatidylcholine transmembrane transporter activity|phosphatidylinositol transporter activity|protein binding			central_nervous_system(1)|kidney(1)|large_intestine(1)|lung(3)|ovary(1)	7				UCEC - Uterine corpus endometrioid carcinoma (25;0.0845)		TTTCTCACCGTCCTTCTCGTA	0.552000													56	89					0	0	1	0	0
RHBDD3	25807	broad.mit.edu	37	22	29656429	29656429	+	Missense_Mutation	SNP	G	G	A			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr22:29656429G>A	ENST00000216085.7	-	6	1293	c.869C>T	c.(868-870)gCg>gTg	p.A290V		NM_012265.1	NP_036397.1	Q9Y3P4	RHBD3_HUMAN	rhomboid domain containing 3	290						integral to membrane	serine-type endopeptidase activity			lung(1)|ovary(1)	2						ATCCAAGGCCGCCCACATCGG	0.672000													2	2					0	0	1	0	0
CAMSAP1	157922	broad.mit.edu	37	9	138713116	138713116	+	Missense_Mutation	SNP	G	G	A			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr9:138713116G>A	ENST00000389532.4	-	11	3455	c.3391C>T	c.(3391-3393)Ccg>Tcg	p.P1131S	CAMSAP1_ENST00000409386.3_Missense_Mutation_p.P1142S|CAMSAP1_ENST00000312405.6_Missense_Mutation_p.P853S|CAMSAP1_ENST00000483991.1_5'UTR	NM_015447.3	NP_056262.3	Q5T5Y3	CAMP1_HUMAN	calmodulin regulated spectrin-associated protein 1	1131						cytoplasm|microtubule				breast(3)|central_nervous_system(2)|endometrium(6)|kidney(4)|large_intestine(11)|lung(16)|ovary(3)|pancreas(1)|skin(1)	47				OV - Ovarian serous cystadenocarcinoma(145;1.4e-06)|Epithelial(140;1.11e-05)		CTCAAGTGCGGGAGCGTCTCT	0.647000													3	46					0	0	1	0	0
BGN	633	broad.mit.edu	37	X	152770767	152770767	+	Missense_Mutation	SNP	G	G	A	rs150272427	byFrequency	TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chrX:152770767G>A	ENST00000331595.4	+	3	496	c.310G>A	c.(310-312)Gag>Aag	p.E104K	BGN_ENST00000480756.1_3'UTR|BGN_ENST00000370204.1_Missense_Mutation_p.E43K	NM_001711.4	NP_001702.1	P21810	PGS1_HUMAN	biglycan	104						proteinaceous extracellular matrix|transport vesicle	extracellular matrix structural constituent			breast(2)|endometrium(3)|large_intestine(1)|lung(9)|ovary(1)	16	all_hematologic(71;4.25e-06)|Acute lymphoblastic leukemia(192;6.56e-05)					CGACATCTCCGAGCTCCGCAA	0.617000													26	44					0	0	1	0	0
TRPV2	51393	broad.mit.edu	37	17	16338272	16338272	+	Missense_Mutation	SNP	C	C	A			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr17:16338272C>A	ENST00000338560.7	+	14	2582	c.2183C>A	c.(2182-2184)gCa>gAa	p.A728E	TRPV2_ENST00000577397.1_Missense_Mutation_p.A298E	NM_016113.4	NP_057197.2	Q9Y5S1	TRPV2_HUMAN	transient receptor potential cation channel, subfamily V, member 2	728					sensory perception	integral to plasma membrane|melanosome	calcium channel activity			breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(7)|lung(9)|ovary(1)|pancreas(1)|prostate(2)|stomach(3)	28				UCEC - Uterine corpus endometrioid carcinoma (92;0.0837)		CCGTCAGGGGCAGGTGTCCCT	0.627000													12	27					4.3838e-07	4.65779e-07	1	1	0
MAPK8IP2	23542	broad.mit.edu	37	22	51044090	51044090	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr22:51044090C>T	ENST00000399908.2	+	5	1860	c.1144C>T	c.(1144-1146)Cgc>Tgc	p.R382C	MAPK8IP2_ENST00000329492.3_Missense_Mutation_p.R647C|MAPK8IP2_ENST00000442429.2_Missense_Mutation_p.R370C|MAPK8IP2_ENST00000399912.1_Missense_Mutation_p.R382C|MAPK8IP2_ENST00000008876.5_Missense_Mutation_p.R353C|MAPK8IP2_ENST00000341339.4_Missense_Mutation_p.R268C	NM_016431.3	NP_057515.1	Q13387	JIP2_HUMAN	mitogen-activated protein kinase 8 interacting protein 2	648					behavioral fear response|dendrite morphogenesis|MAPKKK cascade|nonassociative learning|positive regulation of anti-apoptosis|regulation of excitatory postsynaptic membrane potential|regulation of JNK cascade|regulation of receptor activity|regulation of synaptic transmission, glutamatergic|signal complex assembly|social behavior	cytoplasm|postsynaptic density	beta-amyloid binding|kinesin binding|MAP-kinase scaffold activity|protein kinase activator activity|protein kinase binding			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)	7		all_cancers(38;8.8e-15)|all_epithelial(38;1.12e-12)|all_lung(38;3.07e-05)|Breast(42;6.27e-05)|Lung NSC(38;0.000813)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		OV - Ovarian serous cystadenocarcinoma(4;1.28e-70)|Epithelial(4;3.46e-65)|GBM - Glioblastoma multiforme(4;4.83e-06)|Lung(4;0.125)|BRCA - Breast invasive adenocarcinoma(115;0.205)|LUAD - Lung adenocarcinoma(64;0.247)		CTTCAACATGCGCACGGGGGA	0.652000													4	21					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				11	24					0	0	1	0	0
CES4A	283848	broad.mit.edu	37	16	67036990	67036990	+	Silent	SNP	C	C	G			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr16:67036990C>G	ENST00000540947.2	+	6	892	c.708C>G	c.(706-708)gcC>gcG	p.A236A	CES4A_ENST00000541479.1_Silent_p.A259A|CES4A_ENST00000540579.1_Silent_p.A138A|CES4A_ENST00000398354.1_Silent_p.A236A|CES4A_ENST00000535696.1_Silent_p.A142A|CES4A_ENST00000326686.5_Silent_p.A236A|CES4A_ENST00000338718.4_Silent_p.A259A	NM_173815.6	NP_776176.5	Q5XG92	EST4A_HUMAN	carboxylesterase 4A	236						extracellular region	carboxylesterase activity			large_intestine(2)|liver(2)|lung(4)|ovary(1)	9						CACCCCTAGCCTCGGGTCTCT	0.552000													27	51					0	0	1	0	0
LRP1	4035	broad.mit.edu	37	12	57563020	57563020	+	Missense_Mutation	SNP	C	C	G			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr12:57563020C>G	ENST00000243077.3	+	20	3559	c.3093C>G	c.(3091-3093)caC>caG	p.H1031Q	LRP1_ENST00000553446.1_3'UTR	NM_002332.2	NP_002323.2	Q07954	LRP1_HUMAN	low density lipoprotein receptor-related protein 1	1031	LDL-receptor class A 7.				aorta morphogenesis|apoptotic cell clearance|negative regulation of platelet-derived growth factor receptor-beta signaling pathway|negative regulation of smooth muscle cell migration|negative regulation of Wnt receptor signaling pathway|positive regulation of cholesterol efflux|regulation of actin cytoskeleton organization|regulation of phospholipase A2 activity	coated pit|integral to plasma membrane|nucleus	apolipoprotein E binding|calcium ion binding|lipoprotein transporter activity|protein complex binding|receptor activity			NS(1)|breast(9)|central_nervous_system(3)|cervix(3)|endometrium(33)|haematopoietic_and_lymphoid_tissue(4)|kidney(10)|large_intestine(26)|lung(58)|ovary(10)|pancreas(2)|prostate(11)|skin(7)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(5)	184				BRCA - Breast invasive adenocarcinoma(357;0.0103)	Alteplase(DB00009)|Anistreplase(DB00029)|Antihemophilic Factor(DB00025)|Becaplermin(DB00102)|Coagulation Factor IX(DB00100)|Tenecteplase(DB00031)	TCCCCGAGCACTGGACCTGCG	0.612000													3	46					0	0	1	0	0
SLC6A10P	0	broad.mit.edu	37	16	32890622	32890622	+	RNA	SNP	T	T	G			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr16:32890622T>G	ENST00000330048.5	-	0	3176					NR_003083.2																						CGTTGGTGTTTTTGTAGACCA	0.617000													3	25					0	0	1	0	0
ZNF799	90576	broad.mit.edu	37	19	12501446	12501446	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr19:12501446T>C	ENST00000419318.1	-	4	2419	c.1670A>G	c.(1669-1671)gAa>gGa	p.E557G	CTD-3105H18.14_ENST00000435033.1_Intron|ZNF799_ENST00000430385.3_Missense_Mutation_p.E589G			Q96GE5	ZN799_HUMAN	zinc finger protein 799	589					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(3)|kidney(2)|large_intestine(4)|lung(4)|ovary(2)|prostate(2)|skin(2)	19						TTCCTTACATTCATACGGGTT	0.413000													3	15					0	0	1	0	0
RP11-419C5.2	0	broad.mit.edu	37	16	70011854	70011854	+	Missense_Mutation	SNP	T	T	C	rs145494569	by1000genomes	TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr16:70011854T>C	ENST00000325845.7	-	26	2740	c.671A>G	c.(670-672)aAg>aGg	p.K224R	RP11-419C5.2_ENST00000532298.1_Intron|PDXDC2P_ENST00000531894.1_RNA|RP11-419C5.2_ENST00000525562.1_5'UTR																breast(2)|endometrium(2)|kidney(6)|lung(2)|prostate(1)	13						ACTGTGATGCTTGTAGGCAGC	0.522000													3	15					0	0	1	0	0
LRRIQ3	127255	broad.mit.edu	37	1	74575212	74575213	+	Frame_Shift_Ins	INS	-	-	T			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr1:74575212_74575213insT	ENST00000354431.4	-	5	923_924	c.732_733insA	c.(730-735)aaagcafs	p.A245fs	LRRIQ3_ENST00000395089.1_Frame_Shift_Ins_p.A245fs|LRRIQ3_ENST00000468759.1_5'UTR|LRRIQ3_ENST00000370909.2_Frame_Shift_Ins_p.A137fs	NM_001105659.1	NP_001099129.1	A6PVS8	LRIQ3_HUMAN	leucine-rich repeats and IQ motif containing 3	245				QQEKII -> TAGKNY (in Ref. 1; BAD18621).						NS(2)|breast(1)|central_nervous_system(2)|endometrium(7)|kidney(5)|large_intestine(13)|liver(1)|lung(27)|ovary(3)|prostate(1)|skin(5)|soft_tissue(1)|upper_aerodigestive_tract(5)	73						TTTTCCTGCTGTTTTTTTTTGT	0.327													9	23	---	---	---	---					
AC128709.2	0	broad.mit.edu	37	3	197186599	197186600	+	RNA	INS	-	-	G	rs66804255		TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr3:197186599_197186600insG	ENST00000420213.1	+	0	138																											tgtggtcgggagggatgcagtt	0.604													7	54	---	---	---	---					
RP11-897M7.1	0	broad.mit.edu	37	12	131962167	131962168	+	RNA	INS	-	-	ATA	rs148457819	by1000genomes	TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr12:131962167_131962168insATA	ENST00000535133.1	-	0	195																											tggtaatggtggtgatgatggt	0.426													12	13	---	---	---	---					
RP11-66N24.4	0	broad.mit.edu	37	14	24020895	24020897	+	RNA	DEL	CCT	CCT	-			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr14:24020895_24020897delCCT	ENST00000553985.1	+	0	238				RP11-66N24.4_ENST00000556354.1_RNA	NR_046052.1																						tcctcctcgccctcctcctcctc	0.621													3	5	---	---	---	---					
RP11-426C22.5	0	broad.mit.edu	37	16	29210269	29210269	+	RNA	DEL	G	G	-			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr16:29210269delG	ENST00000562902.1	+	0	200																											ATGATCCTGAGGGAGGGGAGG	0.622													2	4	---	---	---	---					
RP11-405F3.4	0	broad.mit.edu	37	16	57725064	57725073	+	RNA	DEL	AGAAGGAGGG	AGAAGGAGGG	-	rs137989784	by1000genomes	TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr16:57725064_57725073delAGAAGGAGGG	ENST00000563062.1	-	0	463																											aggaggaggaagaaggagggagaaggaggg	0.529													2	4	---	---	---	---					
SPPL2B	56928	broad.mit.edu	37	19	2344118	2344119	+	RNA	DEL	AT	AT	-			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr19:2344118_2344119delAT	ENST00000452401.2	+	0	1190				AC005258.3_ENST00000590001.1_RNA			Q8TCT7	PSL1_HUMAN	signal peptide peptidase like 2B							Golgi membrane|integral to membrane	aspartic-type endopeptidase activity						Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		caccccccccatcaccccgccc	0.738													3	6	---	---	---	---					
AP000282.2	0	broad.mit.edu	37	21	34355469	34355470	+	RNA	INS	-	-	C			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chr21:34355469_34355470insC	ENST00000454622.1	-	0	201				AP000282.2_ENST00000420356.1_RNA																							cctctccccctccctggccctc	0.574													2	4	---	---	---	---					
SAGE1	55511	broad.mit.edu	37	X	134995047	134995047	+	Frame_Shift_Del	DEL	A	A	-			TCGA-EM-A3FK-01A-11D-A21A-08	TCGA-EM-A3FK-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	98d41d18-b4d1-478e-ac23-0eaaa4c5b8d5	23e0a545-3e41-486a-90d1-cc3d672e4a24	g.chrX:134995047delA	ENST00000535938.1	+	20	2873	c.2706delA	c.(2704-2706)agfs	p.R902fs	SAGE1_ENST00000537770.1_Frame_Shift_Del_p.R526fs|SAGE1_ENST00000324447.3_Frame_Shift_Del_p.R902fs|SAGE1_ENST00000370709.3_Frame_Shift_Del_p.R902fs	NM_018666.2	NP_061136.2	Q9NXZ1	SAGE1_HUMAN	sarcoma antigen 1	902										breast(5)|endometrium(5)|large_intestine(10)|lung(23)|ovary(3)|pancreas(1)|prostate(1)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	55	Acute lymphoblastic leukemia(192;0.000127)					AGCACATGAGAAAAAGATAAT	0.368													2	4	---	---	---	---					
