Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
AC226119.5	0	broad.mit.edu	37	4	3952899	3952899	+	RNA	SNP	A	A	T	rs17410906		TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr4:3952899A>T	ENST00000281228.8	-	0	208				FAM86EP_ENST00000313946.8_RNA																							AGCACCGGGCATACTTGACTG	0.557000													4	66					0	0	1	0	0
GTF2E1	2960	broad.mit.edu	37	3	120489597	120489597	+	Silent	SNP	C	C	T			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:120489597C>T	ENST00000283875.5	+	3	564	c.471C>T	c.(469-471)tgC>tgT	p.C157C		NM_005513.2	NP_005504.2	P29083	T2EA_HUMAN	general transcription factor IIE, polypeptide 1, alpha 56kDa	157					interspecies interaction between organisms|regulation of transcription, DNA-dependent|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|viral reproduction	nucleoplasm	protein binding|zinc ion binding			NS(1)|breast(3)|endometrium(1)|kidney(1)|large_intestine(6)|lung(9)|ovary(1)	22				GBM - Glioblastoma multiforme(114;0.159)		GTACTTTTTGCCATACAGAGG	0.418000													4	128					0	0	1	0	0
LINC00969	0	broad.mit.edu	37	3	195400799	195400799	+	RNA	SNP	G	G	A	rs7635172	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:195400799G>A	ENST00000445430.1	+	0	1395																											CAAACTCGCTGTTGGACCTGG	0.597000													3	24					0	0	1	0	0
CUL1	8454	broad.mit.edu	37	7	148427298	148427298	+	Missense_Mutation	SNP	C	C	G			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:148427298C>G	ENST00000325222.4	+	2	363	c.84C>G	c.(82-84)atC>atG	p.I28M	CUL1_ENST00000602748.1_Missense_Mutation_p.I28M|CUL1_ENST00000409469.1_Missense_Mutation_p.I28M	NM_003592.2	NP_003583.2	Q13616	CUL1_HUMAN	cullin 1	28					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell cycle arrest|G1/S transition of mitotic cell cycle|induction of apoptosis by intracellular signals|interspecies interaction between organisms|negative regulation of cell proliferation|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein ubiquitination|S phase of mitotic cell cycle|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	cytosol|nucleoplasm|SCF ubiquitin ligase complex	ubiquitin protein ligase binding			breast(2)|central_nervous_system(2)|endometrium(1)|kidney(5)|large_intestine(10)|liver(2)|lung(10)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	40	Melanoma(164;0.15)		OV - Ovarian serous cystadenocarcinoma(82;0.00291)			GAGCCGGCATCCAGCAGGTGT	0.547000													29	67					0	0	1	0	0
CUL1	8454	broad.mit.edu	37	7	148427233	148427233	+	Nonsense_Mutation	SNP	C	C	T			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:148427233C>T	ENST00000325222.4	+	2	298	c.19C>T	c.(19-21)Cag>Tag	p.Q7*	CUL1_ENST00000602748.1_Nonsense_Mutation_p.Q7*|CUL1_ENST00000409469.1_Nonsense_Mutation_p.Q7*	NM_003592.2	NP_003583.2	Q13616	CUL1_HUMAN	cullin 1	7					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell cycle arrest|G1/S transition of mitotic cell cycle|induction of apoptosis by intracellular signals|interspecies interaction between organisms|negative regulation of cell proliferation|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein ubiquitination|S phase of mitotic cell cycle|SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	cytosol|nucleoplasm|SCF ubiquitin ligase complex	ubiquitin protein ligase binding			breast(2)|central_nervous_system(2)|endometrium(1)|kidney(5)|large_intestine(10)|liver(2)|lung(10)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	40	Melanoma(164;0.15)		OV - Ovarian serous cystadenocarcinoma(82;0.00291)			AACCCGGAGCCAGAACCCCCA	0.527000													32	74					0	0	1	0	0
NUPL2	11097	broad.mit.edu	37	7	23224892	23224892	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:23224892G>A	ENST00000258742.5	+	2	584	c.325G>A	c.(325-327)Gag>Aag	p.E109K	NUPL2_ENST00000410002.3_Missense_Mutation_p.E109K|AC005082.1_ENST00000366347.4_Intron|NUPL2_ENST00000487595.1_3'UTR	NM_007342.2	NP_031368.1	O15504	NUPL2_HUMAN	nucleoporin like 2	109	Interaction with HIV-1 Vpr.				carbohydrate metabolic process|glucose transport|mRNA transport|protein export from nucleus|regulation of glucose transport|transmembrane transport|viral reproduction	cytosol|nuclear membrane|nuclear pore	nuclear export signal receptor activity|nucleic acid binding|zinc ion binding			breast(1)|endometrium(1)|kidney(3)|large_intestine(3)|lung(4)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	19						TAGTCCTGATGAGCAGAAAGA	0.353000													4	83					0	0	1	0	0
SRCAP	10847	broad.mit.edu	37	16	30735845	30735845	+	Silent	SNP	C	C	G			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr16:30735845C>G	ENST00000262518.4	+	25	5485	c.5100C>G	c.(5098-5100)ctC>ctG	p.L1700L	SRCAP_ENST00000395059.2_Silent_p.L1638L|SRCAP_ENST00000344771.4_Silent_p.L1542L	NM_006662.2	NP_006653.2	Q6ZRS2	SRCAP_HUMAN	Snf2-related CREBBP activator protein	1700	Pro-rich.				interspecies interaction between organisms|regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	Golgi apparatus|nucleus|protein complex	ATP binding|DNA binding|helicase activity|histone acetyltransferase activity|transcription coactivator activity			NS(1)|breast(3)|cervix(3)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(22)|liver(3)|lung(62)|ovary(6)|pancreas(1)|prostate(4)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(5)	136			Colorectal(24;0.198)			CTCAGACACTCTCTTTGGGAA	0.572000													4	164					0	0	1	0	0
AC226119.5	0	broad.mit.edu	37	4	3952901	3952901	+	RNA	SNP	A	A	T			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr4:3952901A>T	ENST00000281228.8	-	0	206				FAM86EP_ENST00000313946.8_RNA																							CACCGGGCATACTTGACTGAC	0.552000													4	66					0	0	1	0	0
CLCN2	1181	broad.mit.edu	37	3	184076767	184076767	+	Silent	SNP	G	G	A			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:184076767G>A	ENST00000265593.4	-	2	387	c.216C>T	c.(214-216)tgC>tgT	p.C72C	CLCN2_ENST00000344937.7_Silent_p.C72C|EIF2B5_ENST00000444495.1_Intron|CLCN2_ENST00000434054.2_Silent_p.C72C|CLCN2_ENST00000423355.2_5'UTR|CLCN2_ENST00000457512.1_Silent_p.C72C	NM_004366.5	NP_004357.3	P51788	CLCN2_HUMAN	chloride channel, voltage-sensitive 2	72						chloride channel complex	voltage-gated chloride channel activity			breast(2)|central_nervous_system(4)|endometrium(1)|kidney(3)|large_intestine(4)|lung(9)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	27	all_cancers(143;6.66e-11)|Ovarian(172;0.0339)		Epithelial(37;2.22e-33)|OV - Ovarian serous cystadenocarcinoma(80;2.72e-22)		Lubiprostone(DB01046)	TCTCACCGCGGCATCGGGCGC	0.652000													4	95					0	0	1	0	0
BCL11B	64919	broad.mit.edu	37	14	99641455	99641455	+	Missense_Mutation	SNP	A	A	C			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr14:99641455A>C	ENST00000345514.2	-	3	1771	c.1505T>G	c.(1504-1506)gTg>gGg	p.V502G	BCL11B_ENST00000357195.3_Missense_Mutation_p.V573G|BCL11B_ENST00000443726.2_Missense_Mutation_p.V379G	NM_022898.1	NP_075049.1	Q9C0K0	BC11B_HUMAN	B-cell CLL/lymphoma 11B (zinc finger protein)	573						nucleus	zinc ion binding			NS(3)|breast(1)|central_nervous_system(9)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(2)|lung(9)|prostate(2)|skin(2)	34		Melanoma(154;0.0866)|all_epithelial(191;0.241)		COAD - Colon adenocarcinoma(157;0.103)		gaccccgggcACCCCACCACC	0.711000			T	TLX3	T-ALL								4	5					0	0	1	0	0
SNRNP200	23020	broad.mit.edu	37	2	96950283	96950283	+	Missense_Mutation	SNP	T	T	C			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr2:96950283T>C	ENST00000323853.5	-	31	4282	c.4205A>G	c.(4204-4206)aAc>aGc	p.N1402S	SNRNP200_ENST00000349783.5_Intron	NM_014014.4	NP_054733.2	O75643	U520_HUMAN	small nuclear ribonucleoprotein 200kDa (U5)	1402	Helicase ATP-binding 2.					catalytic step 2 spliceosome|nucleoplasm|U5 snRNP	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			breast(3)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(18)|lung(37)|ovary(7)|prostate(4)|skin(5)|stomach(1)|urinary_tract(1)	90						CACCTTCTTGTTGAGCCTGTC	0.527000													35	57					0	0	1	0	0
LINC00969	0	broad.mit.edu	37	3	195400795	195400795	+	RNA	SNP	C	C	T	rs7615357	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:195400795C>T	ENST00000445430.1	+	0	1391																											GGGGCAAACTCGCTGTTGGAC	0.592000													3	24					0	0	1	0	0
MAPKBP1	23005	broad.mit.edu	37	15	42115806	42115806	+	Missense_Mutation	SNP	C	C	T	rs149990798		TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr15:42115806C>T	ENST00000457542.2	+	29	4046	c.3760C>T	c.(3760-3762)Cgc>Tgc	p.R1254C	MAPKBP1_ENST00000456763.2_Missense_Mutation_p.R1260C|MAPKBP1_ENST00000514566.1_Intron|MAPKBP1_ENST00000260357.7_Missense_Mutation_p.R1093C|MAPKBP1_ENST00000221214.6_Missense_Mutation_p.R1137C	NM_014994.2	NP_055809.2	O60336	MABP1_HUMAN	mitogen-activated protein kinase binding protein 1	1260										breast(6)|central_nervous_system(5)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(14)|lung(11)|ovary(1)|pancreas(1)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	56		all_cancers(109;7.71e-14)|all_epithelial(112;5.15e-12)|Lung NSC(122;3.74e-08)|all_lung(180;1.81e-07)|Melanoma(134;0.0262)		OV - Ovarian serous cystadenocarcinoma(18;3.95e-17)|GBM - Glioblastoma multiforme(94;5.71e-07)|Lung(196;0.0436)|BRCA - Breast invasive adenocarcinoma(123;0.203)|LUSC - Lung squamous cell carcinoma(244;0.225)		CAAGATATCCCGCAGTATCTC	0.627000													29	30					0	0	1	0	0
PRSS3P2	0	broad.mit.edu	37	7	142482242	142482242	+	RNA	SNP	G	G	A	rs143538588	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:142482242G>A	ENST00000603901.1	+	0	622					NR_001296.3																						GGTCTGCAATGGACAGCTTCA	0.493000													4	65					0	0	1	0	0
PRSS3P2	0	broad.mit.edu	37	7	142482229	142482229	+	RNA	SNP	T	T	A	rs145494190	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:142482229T>A	ENST00000603901.1	+	0	609					NR_001296.3													p.P203P(1)									CTGGTGGCCCTGTGGTCTGCA	0.493000													4	61					0	0	1	0	0
MACF1	23499	broad.mit.edu	37	1	39799059	39799060	+	Frame_Shift_Ins	INS	-	-	G			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr1:39799059_39799060insG	ENST00000564288.1	+	37	7576_7577	c.6799_6800insG	c.(6799-6801)ggafs	p.G2267fs	MACF1_ENST00000567887.1_Frame_Shift_Ins_p.G2304fs|MACF1_ENST00000545844.1_Intron|MACF1_ENST00000372915.3_Frame_Shift_Ins_p.G2272fs|MACF1_ENST00000476350.1_Intron|MACF1_ENST00000539005.1_Intron|MACF1_ENST00000289893.4_Frame_Shift_Ins_p.G707fs|MACF1_ENST00000361689.2_Intron|MACF1_ENST00000317713.7_Intron			Q9UPN3	MACF1_HUMAN	microtubule-actin crosslinking factor 1	2272					cell cycle arrest|Golgi to plasma membrane protein transport|positive regulation of Wnt receptor signaling pathway|regulation of epithelial cell migration|regulation of focal adhesion assembly|regulation of microtubule-based process|Wnt receptor signaling pathway|wound healing	Golgi apparatus|microtubule|ruffle membrane	actin filament binding|ATPase activity|calcium ion binding|microtubule binding			breast(11)|central_nervous_system(5)|endometrium(18)|haematopoietic_and_lymphoid_tissue(1)|kidney(11)|large_intestine(36)|lung(78)|ovary(12)|prostate(2)|skin(9)|stomach(2)|upper_aerodigestive_tract(8)|urinary_tract(10)	203	Lung NSC(20;5.57e-06)|Ovarian(52;0.00769)|Acute lymphoblastic leukemia(166;0.074)	Myeloproliferative disorder(586;0.0255)	OV - Ovarian serous cystadenocarcinoma(33;7.78e-19)|Epithelial(16;1.73e-17)|all cancers(16;2.49e-16)|LUSC - Lung squamous cell carcinoma(16;0.00146)|Lung(16;0.00204)			AGATAGTGGCAGGGAAATTTTT	0.391													15	71	---	---	---	---					
HSPD1P6	0	broad.mit.edu	37	3	36810381	36810381	+	RNA	DEL	T	T	-			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:36810381delT	ENST00000424886.1	-	0	405																											GAGTGAGGCCttttttttttt	0.542													2	4	---	---	---	---					
RP11-3P17.4	0	broad.mit.edu	37	3	161146872	161146873	+	RNA	DEL	AT	AT	-			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr3:161146872_161146873delAT	ENST00000473595.1	+	0	1231					NR_102265.1																						TGGTGAAAAGATATATATATAT	0.342													6	12	---	---	---	---					
POU4F2	5458	broad.mit.edu	37	4	147560457	147560458	+	In_Frame_Ins	INS	-	-	GGC	rs67907220		TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr4:147560457_147560458insGGC	ENST00000281321.3	+	1	413_414	c.165_166insGGC	c.(163-168)gggcgg>ggGGCgcgg	p.55_56GR>GAR	AC093887.1_ENST00000584185.1_RNA	NM_004575.2	NP_004566.2	Q12837	PO4F2_HUMAN	POU class 4 homeobox 2	55	Poly-Gly.				estrogen receptor signaling pathway|MAPKKK cascade|negative regulation of transcription from RNA polymerase II promoter	nuclear speck	RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription			NS(1)|breast(1)|endometrium(7)|kidney(3)|large_intestine(11)|lung(8)|skin(1)|upper_aerodigestive_tract(1)	33	all_hematologic(180;0.151)					ACGCTggtggtggcggcggcgg	0.762													5	11	---	---	---	---					
BTN2A2	10385	broad.mit.edu	37	6	26384091	26384093	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr6:26384091_26384093delCCT	ENST00000356709.4	+	2	153_155	c.42_44delCCT	c.(40-45)tcc>tc	p.SL14del	BTN2A2_ENST00000352867.2_In_Frame_Del_p.SL14del|BTN2A2_ENST00000469230.1_In_Frame_Del_p.SL14del|BTN2A2_ENST00000416795.2_In_Frame_Del_p.SL14del|BTN2A2_ENST00000482536.1_In_Frame_Del_p.SL14del|BTN2A2_ENST00000432533.2_In_Frame_Del_p.SL14del	NM_001197240.1|NM_006995.4	NP_001184169.1|NP_008926.2	Q8WVV5	BT2A2_HUMAN	butyrophilin, subfamily 2, member A2	14					negative regulation of activated T cell proliferation|negative regulation of cellular metabolic process|negative regulation of cytokine secretion	integral to membrane				breast(2)|endometrium(3)|large_intestine(5)|lung(13)	23						TGCCAGCCTCcctcctcctcctc	0.581													8	127	---	---	---	---					
STEAP2-AS1	0	broad.mit.edu	37	7	89748927	89748928	+	RNA	INS	-	-	C	rs138239781	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr7:89748927_89748928insC	ENST00000478318.2	-	0	424				DPY19L2P4_ENST00000497063.1_RNA|RP5-1121E10.2_ENST00000471553.1_lincRNA																							GGTGCGGGCCTCCCCCTTCCCC	0.639													4	6	---	---	---	---					
TIMM23	100287932	broad.mit.edu	37	10	51623197	51623198	+	Frame_Shift_Ins	INS	-	-	C			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr10:51623197_51623198insC	ENST00000260867.4	-	1	140_141	c.17_18insG	c.(16-18)gagfs	p.E6fs	TIMM23_ENST00000374064.3_Frame_Shift_Ins_p.E6fs|TIMM23_ENST00000374065.3_Frame_Shift_Ins_p.E6fs	NM_006327.3	NP_006318.1	O14925	TIM23_HUMAN	translocase of inner mitochondrial membrane 23 homolog (yeast)	6					protein targeting to mitochondrion	integral to membrane|mitochondrial inner membrane presequence translocase complex|mitochondrial intermembrane space	P-P-bond-hydrolysis-driven protein transmembrane transporter activity|protein binding			endometrium(1)|large_intestine(1)|pancreas(1)	3						TGTTGCCGCTTCCCCCGCCTCC	0.634													2	4	---	---	---	---					
EP400	57634	broad.mit.edu	37	12	132547093	132547094	+	In_Frame_Ins	INS	-	-	CAG	rs113304321	by1000genomes	TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr12:132547093_132547094insCAG	ENST00000333577.4	+	48	8398_8399	c.8289_8290insCAG	c.(8287-8292)caagca>caCAGagca	p.2763_2763Q>HR	EP400_ENST00000330386.6_In_Frame_Ins_p.2646_2646Q>HR|EP400_ENST00000332482.4_In_Frame_Ins_p.2690_2690Q>HR|EP400_ENST00000389562.2_In_Frame_Ins_p.2726_2726Q>HR|EP400_ENST00000389561.2_In_Frame_Ins_p.2727_2727Q>HR			Q96L91	EP400_HUMAN	E1A binding protein p400	2763	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity	p.Q2726Q(9)		NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcaacaacagcagcagca	0.564													21	46	---	---	---	---					
GJA3	2700	broad.mit.edu	37	13	20716593	20716593	+	Frame_Shift_Del	DEL	G	G	-			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr13:20716593delG	ENST00000241125.3	-	2	1011	c.835delC	c.(835-837)tgfs	p.L279fs		NM_021954.3	NP_068773.2	Q9Y6H8	CXA3_HUMAN	gap junction protein, alpha 3, 46kDa	279					cell-cell signaling|visual perception	connexon complex|integral to membrane				NS(1)|endometrium(1)|kidney(1)|lung(1)|pancreas(1)|prostate(1)|skin(1)	7		all_cancers(29;1.4e-21)|all_epithelial(30;8.75e-19)|all_lung(29;1.28e-17)|Lung SC(185;0.0257)|Ovarian(182;0.0822)		all cancers(112;0.000554)|Epithelial(112;0.000872)|OV - Ovarian serous cystadenocarcinoma(117;0.0105)|Lung(94;0.0251)|LUSC - Lung squamous cell carcinoma(192;0.0784)		GCCTGTCCCAGGGGCGCAGCG	0.761													2	4	---	---	---	---					
RP13-329D4.3	0	broad.mit.edu	37	20	26113543	26113543	+	RNA	DEL	A	A	-			TCGA-FY-A40N-01A-11D-A23M-08	TCGA-FY-A40N-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6f8beba9-a6ff-4e83-8ed6-e1ffc76cc9fc	b8313c2c-a5c7-404f-a9d1-0cf2355f0cfa	g.chr20:26113543delA	ENST00000416563.1	-	0	250																											TCTTTGCCTTAACAACATTAT	0.363													2	4	---	---	---	---					
