Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KLHL36	79786	broad.mit.edu	37	16	84691221	84691221	+	Missense_Mutation	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr16:84691221G>A	ENST00000564996.1	+	3	949	c.808G>A	c.(808-810)Gcc>Acc	p.A270T	KLHL36_ENST00000258157.5_Missense_Mutation_p.A270T	NM_024731.2	NP_079007.2	Q8N4N3	KLH36_HUMAN	kelch-like family member 36	270										endometrium(3)|large_intestine(1)|lung(3)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	13						CATCGAGGAGGCCGTGCGCTA	0.677000													20	54					0	0	1	0	0
KLC2	64837	broad.mit.edu	37	11	66032653	66032653	+	Missense_Mutation	SNP	C	C	G			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr11:66032653C>G	ENST00000394065.2	+	9	1882	c.864C>G	c.(862-864)gaC>gaG	p.D288E	KLC2_ENST00000417856.1_Missense_Mutation_p.D427E|KLC2_ENST00000316924.5_Missense_Mutation_p.D427E|KLC2_ENST00000394067.2_Missense_Mutation_p.D427E|RP11-867G23.1_ENST00000530805.1_RNA|KLC2_ENST00000421552.1_Missense_Mutation_p.D350E|KLC2_ENST00000394078.1_Intron|KLC2_ENST00000394066.2_Missense_Mutation_p.D350E			Q9H0B6	KLC2_HUMAN	kinesin light chain 2	427					blood coagulation	cytosol|kinesin complex|microtubule	microtubule motor activity|protein binding			breast(2)|endometrium(1)|kidney(1)|large_intestine(7)|lung(3)|prostate(5)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(2)	24						AGCGCCGGGACAGCGCCCCCT	0.657000											OREG0021098	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	6	117					0	0	1	0	0
RPF2	84154	broad.mit.edu	37	6	111346773	111346773	+	Silent	SNP	T	T	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr6:111346773T>A	ENST00000441448.2	+	10	1001	c.909T>A	c.(907-909)atT>atA	p.I303I		NM_032194.1	NP_115570.1	Q9H7B2	RPF2_HUMAN	ribosome production factor 2 homolog (S. cerevisiae)	303						nucleolus	protein binding	p.I303I(1)		central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|ovary(2)	7						CAAAAAGAATTAAAAAAAATT	0.368000													8	31					0	0	1	0	0
CACNA1C	775	broad.mit.edu	37	12	2613619	2613619	+	Silent	SNP	C	C	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr12:2613619C>T	ENST00000399634.1	+	8	1131	c.1131C>T	c.(1129-1131)ggC>ggT	p.G377G	CACNA1C_ENST00000399637.1_Intron|CACNA1C_ENST00000491104.1_3'UTR|CACNA1C_ENST00000399601.1_Intron|CACNA1C_ENST00000399595.1_Intron|CACNA1C_ENST00000480911.1_Intron|CACNA1C_ENST00000399606.1_Intron|CACNA1C_ENST00000399649.1_Intron|CACNA1C_ENST00000399621.1_Intron|CACNA1C_ENST00000399629.1_Intron|CACNA1C_ENST00000335762.5_Intron|CACNA1C_ENST00000399603.1_Silent_p.G377G|CACNA1C_ENST00000399638.1_Intron|CACNA1C_ENST00000399641.1_Silent_p.G377G|CACNA1C_ENST00000327702.7_Intron|CACNA1C_ENST00000399644.1_Intron|CACNA1C_ENST00000344100.3_Intron|CACNA1C_ENST00000399655.1_Intron|CACNA1C_ENST00000399591.1_Intron|CACNA1C_ENST00000399617.1_Silent_p.G377G|CACNA1C_ENST00000399597.1_Intron|CACNA1C_ENST00000402845.3_Intron|CACNA1C_ENST00000406454.3_Silent_p.G377G|CACNA1C_ENST00000347598.4_Intron	NM_001167625.1	NP_001161097.1	Q13936	CAC1C_HUMAN	calcium channel, voltage-dependent, L type, alpha 1C subunit	377					axon guidance|calcium ion transport into cytosol|energy reserve metabolic process|regulation of insulin secretion	cytoplasm|postsynaptic density|voltage-gated calcium channel complex	calmodulin binding|voltage-gated calcium channel activity			NS(3)|breast(4)|central_nervous_system(4)|cervix(2)|endometrium(12)|kidney(9)|large_intestine(20)|lung(55)|ovary(10)|pancreas(1)|prostate(5)|skin(3)|upper_aerodigestive_tract(4)	132			OV - Ovarian serous cystadenocarcinoma(31;0.00256)	LUAD - Lung adenocarcinoma(1;0.134)	Ibutilide(DB00308)|Isradipine(DB00270)|Magnesium Sulfate(DB00653)|Mibefradil(DB01388)|Nicardipine(DB00622)|Verapamil(DB00661)	ACGCTATGGGCTATGAGTTAC	0.478000													60	96					0	0	1	0	0
OR7A5	26659	broad.mit.edu	37	19	14938184	14938184	+	Silent	SNP	A	A	G			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr19:14938184A>G	ENST00000322301.3	-	2	957	c.870T>C	c.(868-870)taT>taC	p.Y290Y	OR7A5_ENST00000594432.1_Silent_p.Y290Y|OR7A5_ENST00000601611.1_Intron			Q15622	OR7A5_HUMAN	olfactory receptor, family 7, subfamily A, member 5	290					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.Y290Y(2)		breast(1)|central_nervous_system(4)|endometrium(2)|kidney(4)|large_intestine(3)|lung(6)|pancreas(1)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	26						TCCTCAGACTATAGATAAAGG	0.478000													6	156					0	0	1	0	0
ATF5	22809	broad.mit.edu	37	19	50435872	50435872	+	Silent	SNP	A	A	C			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr19:50435872A>C	ENST00000423777.2	+	3	749	c.372A>C	c.(370-372)ccA>ccC	p.P124P	ATF5_ENST00000595125.1_Silent_p.P124P|CTC-326K19.6_ENST00000451973.1_Intron	NM_001193646.1	NP_001180575.1	Q9Y2D1	ATF5_HUMAN	activating transcription factor 5	124	Interaction with PTP4A1 (By similarity).|Poly-Pro.				regulation of transcription from RNA polymerase II promoter	cytoplasm	protein dimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity			NS(1)|endometrium(2)|large_intestine(1)|skin(3)	7		all_lung(116;0.00318)|all_neural(266;0.107)|Ovarian(192;0.17)		GBM - Glioblastoma multiforme(134;0.00221)|OV - Ovarian serous cystadenocarcinoma(262;0.017)		CCCTCccaccaccctccccgc	0.642000													4	2					0	0	1	0	0
PLAG1	5324	broad.mit.edu	37	8	57079869	57079869	+	Missense_Mutation	SNP	T	T	C	rs138489179	byFrequency	TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr8:57079869T>C	ENST00000316981.3	-	5	915	c.436A>G	c.(436-438)Aca>Gca	p.T146A	PLAG1_ENST00000429357.2_Missense_Mutation_p.T146A|PLAG1_ENST00000423799.2_Missense_Mutation_p.T64A	NM_001114634.1|NM_002655.2	NP_001108106.1|NP_002646.2	Q6DJT9	PLAG1_HUMAN	pleiomorphic adenoma gene 1	146	Decreased nuclear import with localization in the nucleus but also in the cytoplasm.					nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding		CTNNB1/PLAG1(60)|LIFR_ENST00000263409/PLAG1(10)|HAS2/PLAG1(10)|FGFR1_ENST00000447712/PLAG1(28)|COL1A2/PLAG1(3)|CHCHD7/PLAG1(12)|TCEA1_ENST00000521604/PLAG1(3)	breast(3)|central_nervous_system(1)|cervix(1)|kidney(2)|large_intestine(7)|lung(11)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	28		all_lung(136;0.0548)|Lung NSC(129;0.0718)|all_epithelial(80;0.125)	Epithelial(17;0.00179)|all cancers(17;0.0125)			TCACCACTTGTTGCGGCATGC	0.468000			T	"""TCEA1, LIFR, CTNNB1, CHCHD7"""	salivary adenoma								24	26					0	0	1	0	0
CEP192	55125	broad.mit.edu	37	18	13056437	13056437	+	Missense_Mutation	SNP	G	G	C			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr18:13056437G>C	ENST00000506447.1	+	19	3928	c.3848G>C	c.(3847-3849)gGc>gCc	p.G1283A	CEP192_ENST00000325971.8_Missense_Mutation_p.G687A|CEP192_ENST00000430049.2_Missense_Mutation_p.G808A	NM_032142.3	NP_115518.3	B7ZMF0	B7ZMF0_HUMAN	centrosomal protein 192kDa	878										NS(1)|breast(4)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(12)|lung(36)|ovary(4)|pancreas(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	71						TGCCATGCTGGCAATGCCACA	0.547000													25	70					0	0	1	0	0
NAA60	79903	broad.mit.edu	37	16	3526257	3526257	+	Silent	SNP	C	C	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr16:3526257C>T	ENST00000407558.4	+	3	333	c.30C>T	c.(28-30)ctC>ctT	p.L10L	NAA60_ENST00000424546.2_Intron|NAA60_ENST00000573580.1_Intron|NAA60_ENST00000570819.1_Silent_p.L10L|NAA60_ENST00000421765.3_Silent_p.L10L|LA16c-306E5.2_ENST00000575785.1_RNA|NAA60_ENST00000577013.1_Silent_p.L10L|NAA60_ENST00000414063.2_Silent_p.L10L|NAA60_ENST00000572584.1_Silent_p.L10L|NAA60_ENST00000575076.1_Silent_p.L10L|NAA60_ENST00000572942.1_Silent_p.L10L|NAA60_ENST00000360862.5_Intron|NAA60_ENST00000570551.1_Intron|LA16c-306E5.3_ENST00000574423.2_RNA|NAA60_ENST00000576916.1_Silent_p.L10L	NM_001083601.1	NP_001077070.1	Q9H7X0	NAT15_HUMAN	N(alpha)-acetyltransferase 60, NatF catalytic subunit	10							N-acetyltransferase activity			breast(1)|endometrium(1)|kidney(3)|large_intestine(1)|lung(1)	7						CCAGCGCGCTCAGCGAGGTCA	0.607000													20	27					0	0	1	0	0
CCDC6	8030	broad.mit.edu	37	10	61666066	61666066	+	Silent	SNP	T	T	C			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr10:61666066T>C	ENST00000263102.6	-	1	348	c.117A>G	c.(115-117)ggA>ggG	p.G39G		NM_005436.4	NP_005427.2	Q16204	CCDC6_HUMAN	coiled-coil domain containing 6	39	Poly-Gly.					cytoplasm|cytoskeleton	SH3 domain binding|structural constituent of cytoskeleton		CCDC6/RET(4)	breast(3)|central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(6)|ovary(3)|stomach(1)	18				Kidney(211;0.0597)		cgccgccgcctcccccgccgc	0.726000			T	RET	NSCLC								8	55					0	0	1	0	0
SLC8A1	6546	broad.mit.edu	37	2	40657388	40657388	+	Silent	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr2:40657388G>A	ENST00000406785.1	-	2	222	c.33C>T	c.(31-33)ccC>ccT	p.P11P	SLC8A1_ENST00000405901.3_Silent_p.P11P|SLC8A1_ENST00000405269.1_Silent_p.P11P|SLC8A1_ENST00000542756.1_Silent_p.P11P|SLC8A1_ENST00000542024.1_Silent_p.P11P|SLC8A1_ENST00000408028.2_Silent_p.P11P|SLC8A1_ENST00000406391.2_Silent_p.P11P|SLC8A1_ENST00000403092.1_Silent_p.P11P|SLC8A1_ENST00000402441.1_Silent_p.P11P|SLC8A1_ENST00000332839.4_Silent_p.P11P			P32418	NAC1_HUMAN	solute carrier family 8 (sodium/calcium exchanger), member 1	11					cell communication|muscle contraction|platelet activation	integral to plasma membrane	calcium:sodium antiporter activity|calmodulin binding|heat shock protein binding			NS(1)|central_nervous_system(1)|endometrium(7)|kidney(5)|large_intestine(14)|liver(1)|lung(57)|ovary(2)|pancreas(1)|skin(7)|soft_tissue(1)|stomach(1)|upper_aerodigestive_tract(2)	100					Alpha-Linolenic Acid(DB00132)|Icosapent(DB00159)	TTGAAAAGGTGGGTGAAAGAC	0.413000													34	62					0	0	1	0	0
CECR2	27443	broad.mit.edu	37	22	18021606	18021606	+	Nonsense_Mutation	SNP	G	G	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr22:18021606G>T	ENST00000262608.8	+	14	1900	c.1900G>T	c.(1900-1902)Gag>Tag	p.E634*	CECR2_ENST00000400573.4_Nonsense_Mutation_p.E633*|CECR2_ENST00000400585.2_Nonsense_Mutation_p.E492*	NM_031413.3	NP_113601.2	Q9BXF3	CECR2_HUMAN	cat eye syndrome chromosome region, candidate 2	675					chromatin modification|cytokinesis|cytoskeleton organization|DNA fragmentation involved in apoptotic nuclear change|vesicle-mediated transport		protein binding			NS(1)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|lung(22)|ovary(1)|pancreas(1)|prostate(2)|skin(5)|stomach(1)|urinary_tract(1)	59		all_epithelial(15;0.139)		Lung(27;0.146)		TGGAGTCCCGGAGCCACACCC	0.602000													9	51					1.12685e-05	1.14895e-05	1	1	0
CCT6P1	0	broad.mit.edu	37	7	65222986	65222986	+	RNA	SNP	G	G	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr7:65222986G>T	ENST00000442266.1	+	0	578																											GAATTCTGGCGTTTTTTACAA	0.289000													3	17					6.4e-05	6.4e-05	1	1	0
SLC7A11	23657	broad.mit.edu	37	4	139100480	139100480	+	Silent	SNP	C	C	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr4:139100480C>T	ENST00000280612.5	-	11	1614	c.1335G>A	c.(1333-1335)tcG>tcA	p.S445S		NM_014331.3	NP_055146.1	Q9UPY5	XCT_HUMAN	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	445					blood coagulation|cellular nitrogen compound metabolic process|leukocyte migration|response to toxin	integral to membrane|plasma membrane	cystine:glutamate antiporter activity|protein binding			breast(1)|endometrium(4)|kidney(3)|large_intestine(3)|liver(1)|lung(3)|prostate(1)|skin(2)	18	all_hematologic(180;0.166)				L-Cystine(DB00138)|L-Glutamic Acid(DB00142)|Sulfasalazine(DB00795)	TAAATGGGTCCGAATAGAGGG	0.448000													5	93					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414373	20414373	+	Silent	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr9:20414373G>A	ENST00000380338.4	-	5	757	c.471C>T	c.(469-471)agC>agT	p.S157S	MLLT3_ENST00000475957.1_5'UTR|MLLT3_ENST00000429426.2_Silent_p.S154S|MLLT3_ENST00000355930.6_5'UTR	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	157	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S157S(5)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctgctgctactgctgc	0.527000			T	MLL	ALL								6	104					0	0	1	0	0
CAMP	820	broad.mit.edu	37	3	48266103	48266103	+	Missense_Mutation	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr3:48266103G>A	ENST00000296435.2	+	3	485	c.329G>A	c.(328-330)cGg>cAg	p.R110Q	CAMP_ENST00000576243.1_Missense_Mutation_p.R107Q	NM_004345.4	NP_004336.3	P49913	CAMP_HUMAN	cathelicidin antimicrobial peptide	107					killing by host of symbiont cells|negative regulation of growth of symbiont on or near host surface	extracellular region				endometrium(2)|large_intestine(1)|lung(1)|skin(1)|upper_aerodigestive_tract(1)	6				BRCA - Breast invasive adenocarcinoma(193;0.000614)|KIRC - Kidney renal clear cell carcinoma(197;0.00544)|Kidney(197;0.00605)		CTGGTGAAGCGGTGTATGGGG	0.567000													40	132					0	0	1	0	0
ARID3A	1820	broad.mit.edu	37	19	964263	964263	+	Missense_Mutation	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr19:964263G>A	ENST00000263620.3	+	5	1109	c.782G>A	c.(781-783)cGc>cAc	p.R261H		NM_005224.2	NP_005215.1	Q99856	ARI3A_HUMAN	AT rich interactive domain 3A (BRIGHT-like)	261	ARID.					cytoplasm|nucleus	DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(2)|ovary(1)	10		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;1.04e-05)|all_lung(49;1.53e-05)|Breast(49;9.42e-05)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCTGTGAACCGCATCCCCATC	0.637000													4	69					0	0	1	0	0
FOLR3	2352	broad.mit.edu	37	11	71847120	71847120	+	Missense_Mutation	SNP	A	A	G			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr11:71847120A>G	ENST00000445078.2	+	2	187	c.116A>G	c.(115-117)aAg>aGg	p.K39R	FOLR3_ENST00000442948.2_Missense_Mutation_p.K41R|FOLR3_ENST00000456237.1_Missense_Mutation_p.K41R			P41439	FOLR3_HUMAN	folate receptor 3 (gamma)	39					folic acid transport	extracellular region|extrinsic to membrane|membrane fraction	folic acid binding|receptor activity			large_intestine(3)|lung(8)|prostate(2)	13					Folic Acid(DB00158)	ATGAACGCCAAGCACCACAAG	0.632000													92	152					0	0	1	0	0
FAM131B	9715	broad.mit.edu	37	7	143053998	143053998	+	Missense_Mutation	SNP	G	G	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr7:143053998G>A	ENST00000409408.1	-	6	2352	c.644C>T	c.(643-645)cCg>cTg	p.P215L	FAM131B_ENST00000409346.1_Missense_Mutation_p.P215L|FAM131B_ENST00000443739.2_Missense_Mutation_p.P243L|FAM131B_ENST00000409578.1_Missense_Mutation_p.P231L|FAM131B_ENST00000409222.3_Missense_Mutation_p.P215L			Q86XD5	F131B_HUMAN	family with sequence similarity 131, member B	215										breast(1)|endometrium(4)|large_intestine(3)|lung(13)|ovary(1)|skin(2)	24	Melanoma(164;0.205)					TCCTGTGGCCGGAGAGGCAAT	0.557000													52	47					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				41	58					0	0	1	0	0
NPIPB5	100132247	broad.mit.edu	37	16	22545865	22545865	+	Missense_Mutation	SNP	G	G	C	rs147500263	by1000genomes	TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr16:22545865G>C	ENST00000424340.1	+	7	1840	c.1561G>C	c.(1561-1563)Gcc>Ccc	p.A521P	NPIPB5_ENST00000517539.1_Missense_Mutation_p.A521P|NPIPB5_ENST00000415654.1_3'UTR	NM_001135865.1	NP_001129337.1			nuclear pore complex interacting protein family, member B5																		TCAGCTCACTGCCCTTCCACC	0.567000													35	513					0	0	1	0	0
PLEKHN1	84069	broad.mit.edu	37	1	907763	907764	+	Frame_Shift_Ins	INS	-	-	C			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr1:907763_907764insC	ENST00000379409.2	+	9	1147_1148	c.1117_1118insC	c.(1117-1119)cccfs	p.P373fs	PLEKHN1_ENST00000379410.3_Frame_Shift_Ins_p.P321fs|PLEKHN1_ENST00000379407.2_Frame_Shift_Ins_p.P333fs			Q494U1	PKHN1_HUMAN	pleckstrin homology domain containing, family N member 1	373										central_nervous_system(1)|endometrium(3)|kidney(1)|lung(2)|skin(1)|urinary_tract(1)	9	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;9.48e-15)|all_lung(118;9.67e-07)|Lung NSC(185;5.59e-05)|Renal(390;0.00571)|Breast(487;0.0183)|Hepatocellular(190;0.0268)|Myeloproliferative disorder(586;0.028)|Ovarian(437;0.127)|Lung SC(97;0.217)		UCEC - Uterine corpus endometrioid carcinoma (11;0.00459)|Epithelial(90;4.31e-38)|OV - Ovarian serous cystadenocarcinoma(86;5.93e-23)|Colorectal(212;0.000159)|COAD - Colon adenocarcinoma(227;0.000193)|BRCA - Breast invasive adenocarcinoma(365;0.00095)|Kidney(185;0.0023)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0342)|Lung(427;0.199)		CAGGGAGGGGGCCCCGCCGCTG	0.678													6	11	---	---	---	---					
SNED1	25992	broad.mit.edu	37	2	242011113	242011116	+	Frame_Shift_Del	DEL	GAGA	GAGA	-			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr2:242011113_242011116delGAGA	ENST00000310397.8	+	25	3712_3715	c.3712_3715delGAGA	c.(3712-3717)ccfs	p.ET1238fs	SNED1_ENST00000401884.1_Frame_Shift_Del_p.ET1238fs|SNED1_ENST00000405547.3_Frame_Shift_Del_p.ET1238fs|SNED1_ENST00000342631.6_Frame_Shift_Del_p.ET1238fs	NM_001080437.1	NP_001073906.1	Q8TER0	SNED1_HUMAN	sushi, nidogen and EGF-like domains 1	1238					cell-matrix adhesion	extracellular region	calcium ion binding			NS(1)|breast(1)|central_nervous_system(3)|kidney(2)|large_intestine(6)|lung(4)|ovary(3)|prostate(3)|upper_aerodigestive_tract(1)	24		all_cancers(19;7.48e-31)|all_epithelial(40;1.35e-12)|Breast(86;0.000148)|Renal(207;0.00528)|Ovarian(221;0.104)|Esophageal squamous(248;0.131)|all_lung(227;0.17)|all_hematologic(139;0.182)|Melanoma(123;0.238)		Epithelial(32;6.46e-32)|all cancers(36;6.23e-29)|OV - Ovarian serous cystadenocarcinoma(60;2.1e-14)|Kidney(56;6.35e-09)|KIRC - Kidney renal clear cell carcinoma(57;5.98e-08)|BRCA - Breast invasive adenocarcinoma(100;3.66e-06)|Lung(119;0.00072)|LUSC - Lung squamous cell carcinoma(224;0.00553)|Colorectal(34;0.0162)|COAD - Colon adenocarcinoma(134;0.109)		CAGCGCCCCCGAGACCCCCACCCA	0.716													2	4	---	---	---	---					
QRICH1	54870	broad.mit.edu	37	3	49094314	49094316	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr3:49094314_49094316delTGC	ENST00000395443.2	-	3	1789_1791	c.1317_1319delGCA	c.(1315-1320)caa>ca	p.QQ439del	QRICH1_ENST00000479449.1_5'UTR|QRICH1_ENST00000357496.2_In_Frame_Del_p.QQ439del|QRICH1_ENST00000424300.1_In_Frame_Del_p.QQ439del	NM_198880.1	NP_942581.1	Q2TAL8	QRIC1_HUMAN	glutamine-rich 1	439	Gln-rich.									breast(2)|endometrium(5)|large_intestine(8)|lung(8)|ovary(1)|skin(1)	25				BRCA - Breast invasive adenocarcinoma(193;8.88e-05)|Kidney(197;0.00239)|KIRC - Kidney renal clear cell carcinoma(197;0.00258)		AACTTGGAgttgctgctgctgct	0.562													7	135	---	---	---	---					
LINC00971	0	broad.mit.edu	37	3	84741480	84741481	+	RNA	DEL	AA	AA	-	rs140144338		TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr3:84741480_84741481delAA	ENST00000484892.1	-	0	2354					NR_033860.1																						CCTGTCCCAGAAAAAAAAAAAA	0.386													3	6	---	---	---	---					
MFI2	4241	broad.mit.edu	37	3	196733535	196733536	+	Frame_Shift_Ins	INS	-	-	G			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr3:196733535_196733536insG	ENST00000296350.5	-	14	1935_1936	c.1822_1823insC	c.(1822-1824)agcfs	p.S608fs		NM_005929.5	NP_005920.2	P08582	TRFM_HUMAN	antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5	608	Transferrin-like 2.				cellular iron ion homeostasis|iron ion transport	anchored to membrane|extracellular region|integral to plasma membrane	ferric iron binding|protein binding	p.R608*(1)		breast(2)|endometrium(3)|kidney(2)|large_intestine(2)|lung(10)|prostate(1)	20	all_cancers(143;3.95e-09)|Ovarian(172;0.0634)|Breast(254;0.0838)		Epithelial(36;4.55e-24)|all cancers(36;2.87e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.76e-18)|LUSC - Lung squamous cell carcinoma(58;1.51e-06)|Lung(62;1.95e-06)	GBM - Glioblastoma multiforme(46;0.00536)		CACCTCGGCTCGGGCCCCGTTG	0.624													8	77	---	---	---	---					
CLOCK	9575	broad.mit.edu	37	4	56304530	56304532	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr4:56304530_56304532delCTG	ENST00000309964.4	-	21	2528_2530	c.2278_2280delCAG	c.(2278-2280)del	p.Q760del	CLOCK_ENST00000513440.1_In_Frame_Del_p.Q760del|CLOCK_ENST00000381322.1_In_Frame_Del_p.Q760del	NM_004898.3	NP_004889.1	O15516	CLOCK_HUMAN	clock circadian regulator	760	Gln-rich.				circadian rhythm|photoperiodism|positive regulation of transcription from RNA polymerase II promoter	cytoplasm|transcription factor complex	DNA binding|histone acetyltransferase activity|sequence-specific DNA binding transcription factor activity|signal transducer activity			breast(1)|central_nervous_system(3)|cervix(1)|endometrium(4)|kidney(5)|large_intestine(9)|lung(8)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	38	Lung NSC(11;0.00335)|Glioma(25;0.08)|all_epithelial(27;0.0992)|all_neural(26;0.101)		LUSC - Lung squamous cell carcinoma(4;1.62e-07)|Lung(4;1.34e-06)|Epithelial(7;0.0107)			cctgggagctctgctgctgctgc	0.512													8	82	---	---	---	---					
RUSC2	9853	broad.mit.edu	37	9	35555308	35555309	+	Frame_Shift_Ins	INS	-	-	G			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr9:35555308_35555309insG	ENST00000455600.1	+	3	2835_2836	c.2266_2267insG	c.(2266-2268)agcfs	p.S756fs		NM_001135999.1	NP_001129471.1	Q8N2Y8	RUSC2_HUMAN	RUN and SH3 domain containing 2	756						cytosol				NS(1)|breast(3)|endometrium(4)|kidney(1)|large_intestine(9)|lung(4)|ovary(2)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	32			Lung(28;0.000837)|LUSC - Lung squamous cell carcinoma(32;0.00109)|STAD - Stomach adenocarcinoma(86;0.194)			ATCCACTCCCCGAGCCACTGGC	0.663													7	160	---	---	---	---					
RP11-464F9.1	0	broad.mit.edu	37	10	75486922	75486923	+	RNA	INS	-	-	A	rs11387949		TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr10:75486922_75486923insA	ENST00000399449.3	-	0	427				RP11-574K11.28_ENST00000580790.1_RNA|BMS1P4_ENST00000584747.1_RNA																							GCTAACTTAGTAAAGTATAAGA	0.386													5	10	---	---	---	---					
SLC5A8	160728	broad.mit.edu	37	12	101560430	101560430	+	Frame_Shift_Del	DEL	A	A	-			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr12:101560430delA	ENST00000536262.2	-	12	1926	c.1368delT	c.(1366-1368)gtfs	p.V456fs		NM_145913.3	NP_666018.3	Q8N695	SC5A8_HUMAN	solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8	456					apoptosis|sodium ion transport	apical plasma membrane|integral to membrane	monocarboxylic acid transmembrane transporter activity|passive transmembrane transporter activity|symporter activity			breast(1)|endometrium(3)|kidney(1)|large_intestine(9)|lung(29)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	47						CTCCAATTCCAACCCATAGAG	0.393													25	32	---	---	---	---					
CLIP1	6249	broad.mit.edu	37	12	122812690	122812691	+	Frame_Shift_Ins	INS	-	-	T			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr12:122812690_122812691insT	ENST00000358808.2	-	16	3173_3174	c.3019_3020insA	c.(3019-3021)ccafs	p.P1007fs	CLIP1_ENST00000361654.4_Frame_Shift_Ins_p.P896fs|CLIP1_ENST00000302528.7_Frame_Shift_Ins_p.P1007fs|CLIP1_ENST00000540338.1_Frame_Shift_Ins_p.P1018fs|CLIP1_ENST00000537178.1_Frame_Shift_Ins_p.P972fs|CLIP1_ENST00000545889.1_Frame_Shift_Ins_p.P593fs	NM_001247997.1|NM_002956.2	NP_001234926.1|NP_002947.1	P30622	CLIP1_HUMAN	CAP-GLY domain containing linker protein 1	1018					mitotic prometaphase|positive regulation of microtubule polymerization	centrosome|cytosol|endosome|intermediate filament|kinetochore	nucleic acid binding|protein homodimerization activity|zinc ion binding			NS(1)|breast(5)|endometrium(4)|kidney(5)|large_intestine(16)|liver(1)|lung(21)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	60	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.81e-05)|Epithelial(86;6.85e-05)|BRCA - Breast invasive adenocarcinoma(302;0.226)		CTGGTTGTGGCTTGTTTCCATT	0.505													15	247	---	---	---	---					
OR4N2	390429	broad.mit.edu	37	14	20296055	20296056	+	Frame_Shift_Ins	INS	-	-	T	rs149523724	by1000genomes	TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr14:20296055_20296056insT	ENST00000568211.1	+	1	448_449	c.448_449insT	c.(448-450)tggfs	p.W150fs	OR4N2_ENST00000315947.1_Frame_Shift_Ins_p.W150fs			Q8NGD1	OR4N2_HUMAN	olfactory receptor, family 4, subfamily N, member 2	150					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|liver(1)|lung(32)|ovary(2)|prostate(1)|skin(2)|stomach(2)	52	all_cancers(95;0.00108)		Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)		GGCTCTGTGGCTTGGGGGTTTT	0.530													84	484	---	---	---	---					
PLA2G4F	255189	broad.mit.edu	37	15	42439919	42439920	+	Frame_Shift_Ins	INS	-	-	C	rs139732075	by1000genomes	TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr15:42439919_42439920insC	ENST00000397272.3	-	12	1197_1198	c.1106_1107insG	c.(1105-1107)cgcfs	p.R369fs	PLA2G4F_ENST00000382396.4_Frame_Shift_Ins_p.R367fs	NM_213600.3	NP_998765.3	Q68DD2	PA24F_HUMAN	phospholipase A2, group IVF	367	PLA2c.				phospholipid catabolic process	cytosol|lysosomal membrane	metal ion binding|phospholipase A2 activity			breast(1)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(3)|liver(1)|lung(12)|ovary(4)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	32		all_cancers(109;4.82e-12)|all_epithelial(112;5.64e-11)|Lung NSC(122;2.17e-07)|all_lung(180;8.79e-07)|Melanoma(134;0.091)		GBM - Glioblastoma multiforme(94;8.97e-07)		AAGACATGGCTCGGGTTCCACC	0.554													7	168	---	---	---	---					
IGDCC4	57722	broad.mit.edu	37	15	65678327	65678328	+	Frame_Shift_Ins	INS	-	-	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr15:65678327_65678328insA	ENST00000352385.2	-	18	3230_3231	c.3021_3022insT	c.(3019-3024)ctgcccfs	p.P1008fs		NM_020962.1	NP_066013.1	Q8TDY8	IGDC4_HUMAN	immunoglobulin superfamily, DCC subclass, member 4	1008						integral to membrane|plasma membrane		p.G1008C(1)		NS(1)|central_nervous_system(1)|endometrium(1)|large_intestine(7)|lung(24)|ovary(1)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)	44						CTGGGGGGGCCAAGCCGAGCTC	0.663											OREG0023195	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	9	41	---	---	---	---					
LRRC36	55282	broad.mit.edu	37	16	67399260	67399261	+	Splice_Site	INS	-	-	A			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr16:67399260_67399261insA	ENST00000329956.6	+	7	773		c.e7+2		LRRC36_ENST00000541146.1_Intron|LRRC36_ENST00000563189.1_Splice_Site|LRRC36_ENST00000435835.3_Splice_Site|LRRC36_ENST00000290940.7_Intron	NM_018296.5	NP_060766.5	Q1X8D7	LRC36_HUMAN	leucine rich repeat containing 36									p.?(1)		endometrium(4)|kidney(2)|large_intestine(5)|lung(4)|ovary(1)|prostate(4)|skin(3)|upper_aerodigestive_tract(1)	24		Ovarian(137;0.192)		OV - Ovarian serous cystadenocarcinoma(108;0.0669)|Epithelial(162;0.161)		AGGAAGATGGTAAATATTTTGC	0.431													32	43	---	---	---	---					
CDC27	996	broad.mit.edu	37	17	45219612	45219612	+	Frame_Shift_Del	DEL	A	A	-			TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr17:45219612delA	ENST00000066544.3	-	11	1454	c.1361delT	c.(1360-1362)cafs	p.L454fs	CDC27_ENST00000531206.1_Frame_Shift_Del_p.L460fs|CDC27_ENST00000527547.1_Frame_Shift_Del_p.L454fs|CDC27_ENST00000446365.2_Frame_Shift_Del_p.L393fs	NM_001114091.1|NM_001256.3	NP_001107563.1|NP_001247.3	P30260	CDC27_HUMAN	cell division cycle 27	454					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule	protein phosphatase binding			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2)	90						TGCTTTTTGTAGATTAAAGGC	0.308													7	55	---	---	---	---					
TPTEP1	0	broad.mit.edu	37	22	17131536	17131537	+	RNA	INS	-	-	CTG	rs34452519		TCGA-H2-A422-01A-11D-A23M-08	TCGA-H2-A422-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a09c40e3-3da4-4a6f-bc1b-886d6a6c6396	d8ec6736-9410-40cc-9570-5514962644ef	g.chr22:17131536_17131537insCTG	ENST00000426585.1	+	0	2562_2563																											TGCCCACTCTTCTGGTCTCATG	0.540													2	4	---	---	---	---					
