Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CPE	1363	broad.mit.edu	37	4	166405633	166405633	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr4:166405633G>A	ENST00000402744.4	+	5	1130	c.850G>A	c.(850-852)Gca>Aca	p.A284T		NM_001873.2	NP_001864.1	P16870	CBPE_HUMAN	carboxypeptidase E	284					cardiac left ventricle morphogenesis|neuropeptide signaling pathway|protein modification process	extracellular region|nucleus|plasma membrane	metallocarboxypeptidase activity|protein binding|zinc ion binding	p.A284T(1)		endometrium(2)|large_intestine(10)|lung(9)|ovary(1)|prostate(1)|skin(2)|urinary_tract(1)	26	all_hematologic(180;0.221)	Prostate(90;0.0962)|Melanoma(52;0.18)		GBM - Glioblastoma multiforme(119;0.137)	Glucagon recombinant(DB00040)|Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)	CTTGGCCCGGGCATACTCTTC	0.498000													7	527					0	0	0.047766	0	0
RABL6	55684	broad.mit.edu	37	9	139733836	139733836	+	Silent	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr9:139733836G>A	ENST00000371675.3	+	12	2196	c.1311G>A	c.(1309-1311)tcG>tcA	p.S437S	RABL6_ENST00000357466.2_Intron|RABL6_ENST00000432842.2_3'UTR|RABL6_ENST00000371663.4_Silent_p.S553S|RABL6_ENST00000311502.7_Silent_p.S552S					RAB, member RAS oncogene family-like 6																		AGGCCTCCTCGTCGGAGAGTG	0.642000													6	32					0	0	0.021553	0	0
APPBP2	10513	broad.mit.edu	37	17	58539389	58539389	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:58539389C>T	ENST00000083182.3	-	7	1083	c.796G>A	c.(796-798)Gaa>Aaa	p.E266K	APPBP2_ENST00000592995.1_5'UTR	NM_006380.2	NP_006371.2	Q92624	APBP2_HUMAN	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	266					intracellular protein transport	cytoplasmic vesicle membrane|microtubule|microtubule associated complex|nucleus	microtubule motor activity|protein binding			breast(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(17)|pancreas(1)|urinary_tract(1)	25	all_neural(34;0.0878)|Medulloblastoma(34;0.0922)		Epithelial(12;3.67e-13)|all cancers(12;1.44e-11)|Colorectal(3;0.01)			ATTAACTGTTCTGCCTTCTTA	0.289000													4	241					0	0	0.009096	0	0
KIF4B	285643	broad.mit.edu	37	5	154395057	154395057	+	Silent	SNP	C	C	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr5:154395057C>T	ENST00000435029.4	+	1	1798	c.1638C>T	c.(1636-1638)aaC>aaT	p.N546N		NM_001099293.1	NP_001092763.1	Q2VIQ3	KIF4B_HUMAN	kinesin family member 4B	546					axon guidance|blood coagulation|microtubule-based movement	cytosol|microtubule|nuclear matrix	ATP binding|DNA binding|microtubule motor activity			breast(1)|central_nervous_system(1)|endometrium(7)|kidney(6)|large_intestine(13)|lung(27)|ovary(2)|upper_aerodigestive_tract(1)	58	Renal(175;0.00488)	Medulloblastoma(196;0.0523)	KIRC - Kidney renal clear cell carcinoma(527;0.00112)			TGACTCAGAACGACAACCAAC	0.418000													22	50					0	0	0.055883	0	0
ARHGAP26	23092	broad.mit.edu	37	5	142500590	142500590	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr5:142500590G>A	ENST00000378004.3	+	18	1931	c.1576G>A	c.(1576-1578)Gca>Aca	p.A526T	ARHGAP26_ENST00000274498.4_Missense_Mutation_p.A526T	NM_001135608.1	NP_001129080.1	Q9UNA1	RHG26_HUMAN	Rho GTPase activating protein 26	526	Rho-GAP.				actin cytoskeleton organization|filopodium assembly|nervous system development|small GTPase mediated signal transduction	cytoskeleton|cytosol|focal adhesion	cytoskeletal adaptor activity|Rho GTPase activator activity|SH3 domain binding			autonomic_ganglia(1)|breast(1)|central_nervous_system(2)|endometrium(4)|kidney(3)|large_intestine(6)|lung(7)|ovary(1)	25		all_hematologic(541;0.0416)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			GATGACGGTGGCAAACCTTGG	0.453000													4	206					0	0	0.014758	0	0
GALNT16	57452	broad.mit.edu	37	14	69795278	69795278	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr14:69795278G>A	ENST00000337827.4	+	6	1007	c.680G>A	c.(679-681)cGg>cAg	p.R227Q	GALNT16_ENST00000553669.1_Missense_Mutation_p.R227Q|GALNT16_ENST00000448469.3_Missense_Mutation_p.R227Q	NM_001168368.1|NM_020692.2	NP_001161840.1|NP_065743.2			UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16																		ATGCTGCAGCGGGTGAAGGAG	0.622000													24	62					0	0	0.041601	0	0
CEP192	55125	broad.mit.edu	37	18	13068880	13068880	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr18:13068880G>A	ENST00000506447.1	+	25	4932	c.4852G>A	c.(4852-4854)Gca>Aca	p.A1618T	CEP192_ENST00000430049.2_Missense_Mutation_p.A1143T|CEP192_ENST00000325971.8_Missense_Mutation_p.A1022T	NM_032142.3	NP_115518.3	B7ZMF0	B7ZMF0_HUMAN	centrosomal protein 192kDa	1213										NS(1)|breast(4)|cervix(1)|endometrium(5)|kidney(2)|large_intestine(12)|lung(36)|ovary(4)|pancreas(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	71						AGAATTCTCGGCAAAAGTTGA	0.438000													4	156					0	0	0.021553	0	0
NBPF10	100132406	broad.mit.edu	37	1	145367739	145367739	+	Silent	SNP	A	A	G	rs146714035	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr1:145367739A>G	ENST00000342960.5	+	83	10370	c.10335A>G	c.(10333-10335)aaA>aaG	p.K3445K	NBPF10_ENST00000369339.2_Intron|NBPF10_ENST00000369338.1_Intron	NM_001039703.4	NP_001034792.4	A6NDV3	A6NDV3_HUMAN	neuroblastoma breakpoint family, member 10	3445								p.K3445K(4)		NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		ggaaggggaaaaaaagaaggg	0.413000													3	119					0	0	0.004672	0	0
SNX7	51375	broad.mit.edu	37	1	99161131	99161131	+	Missense_Mutation	SNP	G	G	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr1:99161131G>T	ENST00000370189.5	+	6	869	c.505G>T	c.(505-507)Gtc>Ttc	p.V169F	SNX7_ENST00000529992.1_Missense_Mutation_p.V178F|SNX7_ENST00000306121.3_Missense_Mutation_p.V233F			Q9UNH6	SNX7_HUMAN	sorting nexin 7	169					cell communication|protein transport	cytoplasmic vesicle membrane	phosphatidylinositol binding|protein binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(2)|lung(5)|ovary(2)	13		all_epithelial(167;7.64e-07)|all_lung(203;0.0006)|Lung NSC(277;0.00137)		Epithelial(280;0.0521)|all cancers(265;0.0687)|COAD - Colon adenocarcinoma(174;0.15)|Lung(183;0.207)|Colorectal(170;0.234)		GGGGCAAACCGTCAGAGCTGT	0.403000													33	75					4.3181e-19	5.11354e-19	0.054565	1	0
AGPAT6	137964	broad.mit.edu	37	8	41456786	41456786	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr8:41456786G>A	ENST00000396987.3	+	2	1055	c.128G>A	c.(127-129)cGc>cAc	p.R43H		NM_178819.3	NP_848934.1	Q86UL3	GPAT4_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase 6	43					acyl-CoA metabolic process|lactation|phosphatidylcholine biosynthetic process|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|membrane fraction	glycerol-3-phosphate O-acyltransferase activity	p.R43H(2)		endometrium(3)|kidney(2)|large_intestine(3)|lung(6)	14	Ovarian(28;0.00769)|Colorectal(14;0.0202)|Lung SC(25;0.211)	all_lung(54;0.0131)|Lung NSC(58;0.0363)|Hepatocellular(245;0.0462)|Esophageal squamous(32;0.0844)	OV - Ovarian serous cystadenocarcinoma(14;0.00126)|Colorectal(10;0.0014)|Lung(22;0.00177)|LUSC - Lung squamous cell carcinoma(45;0.00392)|COAD - Colon adenocarcinoma(11;0.0147)			TTTGGTATCCGCAAACTCTAC	0.433000													4	183					0	0	0.009096	0	0
PIWIL2	55124	broad.mit.edu	37	8	22211863	22211863	+	Missense_Mutation	SNP	G	G	A	rs150723884	byFrequency	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr8:22211863G>A	ENST00000356766.6	+	22	2885	c.2737G>A	c.(2737-2739)Gca>Aca	p.A913T	PIWIL2_ENST00000454009.2_Missense_Mutation_p.A913T|PIWIL2_ENST00000521356.1_Intron	NM_018068.3	NP_060538.2	Q8TC59	PIWL2_HUMAN	piwi-like RNA-mediated gene silencing 2	913	Piwi.				DNA methylation involved in gamete generation|gene silencing by RNA|germ-line stem cell maintenance|multicellular organismal development|oogenesis|piRNA metabolic process|positive regulation of translation|RNA 5'-end processing|spermatogenesis	chromatoid body|pi-body	piRNA binding			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(14)|lung(14)|prostate(4)|skin(5)|stomach(1)|upper_aerodigestive_tract(1)	46				Colorectal(74;0.018)|COAD - Colon adenocarcinoma(73;0.0707)		TCTCAACACCGCAAACCTGAG	0.463000													4	163					0	0	0.009096	0	0
FAM86DP	0	broad.mit.edu	37	3	75475709	75475709	+	RNA	SNP	T	T	C			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr3:75475709T>C	ENST00000459803.1	-	0	820					NR_024241.1													p.I261V(1)									CTCCGCAGGATCCCGACCAGC	0.562000													3	47					0	0	0.009096	0	0
HERC2P9	0	broad.mit.edu	37	15	28929385	28929385	+	RNA	SNP	T	T	C	rs692172	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr15:28929385T>C	ENST00000528584.1	+	0	1922					NR_036443.1																						CACGCTGCGGTGGTCTTGCAT	0.453000													4	52					0	0	0.009096	0	0
KRTAP9-2	83899	broad.mit.edu	37	17	39383275	39383275	+	Silent	SNP	C	C	G			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:39383275C>G	ENST00000377721.3	+	1	376	c.369C>G	c.(367-369)ccC>ccG	p.P123P	KRTAP9-2_ENST00000455970.2_Silent_p.P107P	NM_031961.2	NP_114167.2	Q9BYQ4	KRA92_HUMAN	keratin associated protein 9-2	123	17 X 5 AA repeats of C-C-[RQVSGE]-[SPTQ]- [TASP].					keratin filament	protein binding			large_intestine(1)|lung(6)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	11		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000397)			GCTACTACCCCACGACTGTCT	0.627000													3	171					0	0	0.004672	0	0
FADS6	283985	broad.mit.edu	37	17	72874555	72874555	+	Missense_Mutation	SNP	C	C	T	rs145096183	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:72874555C>T	ENST00000310226.6	-	6	972	c.958G>A	c.(958-960)Gag>Aag	p.E320K		NM_178128.3	NP_835229.2	Q8N9I5	FADS6_HUMAN	fatty acid desaturase 6	326					fatty acid biosynthetic process	integral to membrane	oxidoreductase activity			endometrium(3)|kidney(1)|lung(4)	8	all_lung(278;0.172)|Lung NSC(278;0.207)					TATGAGTCCTCGTTGTACGGT	0.587000													20	65					0	0	0.043863	0	0
SI	6476	broad.mit.edu	37	3	164741469	164741469	+	Silent	SNP	T	T	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr3:164741469T>A	ENST00000264382.3	-	26	3050	c.2988A>T	c.(2986-2988)acA>acT	p.T996T		NM_001041.3	NP_001032.2	P14410	SUIS_HUMAN	sucrase-isomaltase (alpha-glucosidase)	996	Isomaltase.				carbohydrate metabolic process|polysaccharide digestion	apical plasma membrane|brush border|Golgi apparatus|integral to membrane	carbohydrate binding|oligo-1,6-glucosidase activity|sucrose alpha-glucosidase activity			NS(4)|breast(1)|central_nervous_system(2)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(6)|kidney(10)|large_intestine(18)|lung(124)|ovary(9)|pancreas(1)|prostate(6)|skin(6)|upper_aerodigestive_tract(16)|urinary_tract(1)	218		Prostate(884;0.00314)|Melanoma(1037;0.0153)|all_neural(597;0.0199)			Acarbose(DB00284)	GGAGGTCAGCTGTTATACCCA	0.403000										HNSCC(35;0.089)			29	75					0	0	0.037714	0	0
HCN1	348980	broad.mit.edu	37	5	45262699	45262699	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr5:45262699G>A	ENST00000303230.4	-	8	2054	c.1997C>T	c.(1996-1998)cCg>cTg	p.P666L		NM_021072.3	NP_066550.2	O60741	HCN1_HUMAN	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	666						integral to membrane	cAMP binding|sodium channel activity|voltage-gated potassium channel activity			NS(3)|breast(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(21)|liver(1)|lung(98)|ovary(1)|prostate(7)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(5)	156						TGTGTACACCGGTGGAGATTG	0.577000													4	103					0	0	0.021553	0	0
ARRB1	408	broad.mit.edu	37	11	74979939	74979939	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr11:74979939G>A	ENST00000420843.2	-	14	1184	c.1087C>T	c.(1087-1089)Cgg>Tgg	p.R363W	ARRB1_ENST00000393505.4_Missense_Mutation_p.R363W|ARRB1_ENST00000360025.3_Missense_Mutation_p.R355W	NM_004041.4	NP_004032.2	P49407	ARRB1_HUMAN	arrestin, beta 1	363	Interaction with TRAF6.				G-protein coupled receptor internalization|histone H4 acetylation|negative regulation of interleukin-6 production|negative regulation of interleukin-8 production|negative regulation of NF-kappaB transcription factor activity|negative regulation of protein ubiquitination|platelet activation|positive regulation of ERK1 and ERK2 cascade|positive regulation of histone acetylation|positive regulation of Rho protein signal transduction|positive regulation of transcription from RNA polymerase II promoter|post-Golgi vesicle-mediated transport|proteasomal ubiquitin-dependent protein catabolic process|protein transport|protein ubiquitination|signal transduction|stress fiber assembly|transcription from RNA polymerase II promoter	chromatin|coated pit|cytoplasmic vesicle membrane|cytosol|Golgi membrane|lysosomal membrane|membrane fraction|nucleus|plasma membrane|pseudopodium|soluble fraction	angiotensin receptor binding|enzyme inhibitor activity|GTPase activator activity|insulin-like growth factor receptor binding|transcription factor binding|transcription regulatory region DNA binding|ubiquitin protein ligase binding			breast(4)|large_intestine(2)|lung(4)|prostate(1)	11						TCACCTTCCCGATGCGGGGGT	0.627000													49	108					0	0	0.048971	0	0
ATL1	51062	broad.mit.edu	37	14	51054695	51054695	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr14:51054695G>A	ENST00000441560.2	+	3	662	c.181G>A	c.(181-183)Gct>Act	p.A61T	ATL1_ENST00000354525.4_Missense_Mutation_p.A61T|ATL1_ENST00000358385.6_Missense_Mutation_p.A61T|ATL1_ENST00000357032.3_Missense_Mutation_p.A61T	NM_001127713.1	NP_001121185.1	Q8WXF7	ATLA1_HUMAN	atlastin GTPase 1	61					axonogenesis|cell death|endoplasmic reticulum organization|protein homooligomerization	axon|endoplasmic reticulum membrane|Golgi cis cisterna|Golgi membrane|integral to membrane|microsome	GTP binding|GTPase activity|identical protein binding			central_nervous_system(1)|cervix(2)|large_intestine(4)|liver(1)|lung(6)|ovary(1)|skin(3)	18						TCTCTCGGAGGCTGTCAGAGA	0.433000													6	278					0	0	0.038147	0	0
KRTAP4-11	653240	broad.mit.edu	37	17	39274150	39274150	+	Missense_Mutation	SNP	T	T	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:39274150T>A	ENST00000391413.2	-	1	456	c.418A>T	c.(418-420)Agc>Tgc	p.S140C		NM_033059.3	NP_149048.2	Q9BYQ6	KR411_HUMAN	keratin associated protein 4-11	140	27 X 5 AA repeats of C-C-[GIKRQVHEL]- [SPTR]-[STVQRMC].					keratin filament		p.S140C(2)		endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|lung(8)|prostate(5)|skin(1)	33		Breast(137;0.000496)	STAD - Stomach adenocarcinoma(17;0.000371)			ctggagatgctgcagctgggg	0.672000													4	21					0	0	0.105934	0	0
GCN1L1	10985	broad.mit.edu	37	12	120589045	120589045	+	Missense_Mutation	SNP	C	C	G			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr12:120589045C>G	ENST00000300648.6	-	34	4225	c.4213G>C	c.(4213-4215)Gtg>Ctg	p.V1405L		NM_006836.1	NP_006827.1	Q92616	GCN1L_HUMAN	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	1405					regulation of translation	ribosome	protein binding|translation factor activity, nucleic acid binding			NS(2)|breast(2)|cervix(2)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(13)|liver(1)|lung(36)|ovary(4)|prostate(7)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(2)	94	all_neural(191;0.0804)|Medulloblastoma(191;0.0922)					AGGCCCTTCACCAGGCCCGCC	0.602000													5	98					0	0	0.014758	0	0
FAM50B	26240	broad.mit.edu	37	6	3850220	3850220	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr6:3850220G>A	ENST00000380274.1	+	1	601	c.175G>A	c.(175-177)Gag>Aag	p.E59K	FAM50B_ENST00000380272.3_Missense_Mutation_p.E59K			Q9Y247	FA50B_HUMAN	family with sequence similarity 50, member B	59						nucleus				cervix(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(2)|pancreas(1)|prostate(3)|urinary_tract(3)	17	Ovarian(93;0.0925)	all_hematologic(90;0.108)				CGTGGAGGCCGAGCTGAAGTC	0.662000													15	30					0	0	0.024245	0	0
OPLAH	26873	broad.mit.edu	37	8	145113008	145113008	+	Silent	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr8:145113008G>A	ENST00000426825.1	-	8	1074	c.993C>T	c.(991-993)caC>caT	p.H331H	OPLAH_ENST00000534424.1_5'UTR	NM_017570.3	NP_060040.1	O14841	OPLA_HUMAN	5-oxoprolinase (ATP-hydrolysing)	331							5-oxoprolinase (ATP-hydrolyzing) activity|ATP binding			breast(1)|central_nervous_system(1)|endometrium(1)|lung(13)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)	20	all_cancers(97;1.06e-10)|all_epithelial(106;1.5e-09)|Lung NSC(106;5.89e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155)		OV - Ovarian serous cystadenocarcinoma(54;6.79e-41)|Epithelial(56;1.02e-39)|all cancers(56;2.24e-35)|Colorectal(110;0.055)|BRCA - Breast invasive adenocarcinoma(115;0.105)		L-Glutamic Acid(DB00142)	CCTCGAAGACGTGCTCGAATT	0.662000													4	131					0	0	0.009096	0	0
MYH13	8735	broad.mit.edu	37	17	10209906	10209906	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:10209906G>A	ENST00000418404.3	-	36	5499	c.5336C>T	c.(5335-5337)aCc>aTc	p.T1779I	MYH13_ENST00000570743.1_Missense_Mutation_p.T1779I|MYH13_ENST00000252172.4_Missense_Mutation_p.T1779I			Q9UKX3	MYH13_HUMAN	myosin, heavy chain 13, skeletal muscle	1779					muscle contraction	muscle myosin complex|myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|microfilament motor activity			breast(3)|cervix(2)|endometrium(11)|kidney(7)|large_intestine(21)|lung(48)|ovary(7)|skin(2)|upper_aerodigestive_tract(5)|urinary_tract(2)	108						GTGGGCGCTGGTGTCCTGTTC	0.592000													26	129					0	0	0.108266	0	0
ATXN10	25814	broad.mit.edu	37	22	46125386	46125386	+	Silent	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr22:46125386G>A	ENST00000252934.5	+	7	1075	c.810G>A	c.(808-810)cgG>cgA	p.R270R	ATXN10_ENST00000381061.4_Silent_p.R206R	NM_013236.3	NP_037368.1	Q9UBB4	ATX10_HUMAN	ataxin 10	270					cell death|neuron projection development	dendrite|neuronal cell body|perinuclear region of cytoplasm				central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(3)|ovary(1)|skin(1)	10		Ovarian(80;0.00973)|all_neural(38;0.0417)		UCEC - Uterine corpus endometrioid carcinoma (28;0.0223)		TGTTTTTGCGGCATGCTGAGT	0.468000													4	173					0	0	0.009096	0	0
CD300LF	146722	broad.mit.edu	37	17	72692351	72692351	+	Missense_Mutation	SNP	C	C	T	rs149416788		TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:72692351C>T	ENST00000469092.1	-	5	737	c.461G>A	c.(460-462)cGg>cAg	p.R154Q	CD300LF_ENST00000343125.4_Missense_Mutation_p.R154Q|CD300LF_ENST00000301573.9_Missense_Mutation_p.R204Q|CD300LF_ENST00000583937.1_Missense_Mutation_p.G204R|CD300LF_ENST00000326165.6_Missense_Mutation_p.G189R|CD300LF_ENST00000464910.1_Missense_Mutation_p.G192R|RAB37_ENST00000340415.3_Intron|CD300LF_ENST00000581500.1_Intron|RAB37_ENST00000402449.4_Intron|CD300LF_ENST00000361254.4_Intron			Q8TDQ1	CLM1_HUMAN	CD300 molecule-like family member f	0						integral to membrane|plasma membrane	receptor activity			endometrium(2)|large_intestine(1)|lung(3)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	12						GGGGACATCCCGGCTGCTAAA	0.493000													5	211					0	0	0.014758	0	0
NPAS2	4862	broad.mit.edu	37	2	101592002	101592002	+	Silent	SNP	C	C	T	rs140730823	byFrequency	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr2:101592002C>T	ENST00000335681.5	+	14	1650	c.1365C>T	c.(1363-1365)ccC>ccT	p.P455P	NPAS2_ENST00000542504.1_Silent_p.P520P|AC016738.3_ENST00000439150.1_RNA|AC016738.3_ENST00000446644.1_RNA	NM_002518.3	NP_002509.2	Q99743	NPAS2_HUMAN	neuronal PAS domain protein 2	455					central nervous system development|positive regulation of transcription from RNA polymerase II promoter|rhythmic process	transcription factor complex	DNA binding|Hsp90 protein binding|sequence-specific DNA binding transcription factor activity|signal transducer activity			cervix(1)|endometrium(3)|large_intestine(7)|lung(9)|ovary(3)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29						TACCTGTCCCCGGGCTCAGCC	0.612000													6	256					0	0	0.021553	0	0
ZC3H13	23091	broad.mit.edu	37	13	46563027	46563027	+	Missense_Mutation	SNP	T	T	C			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr13:46563027T>C	ENST00000242848.4	-	9	1498	c.1150A>G	c.(1150-1152)Aga>Gga	p.R384G	ZC3H13_ENST00000282007.3_Missense_Mutation_p.R384G			Q5T200	ZC3HD_HUMAN	zinc finger CCCH-type containing 13	384	Arg/Ser-rich.						nucleic acid binding|zinc ion binding			cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(27)|lung(25)|ovary(2)|prostate(3)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	79		Lung NSC(96;7.26e-05)|Breast(56;0.000118)|Prostate(109;0.00217)|Hepatocellular(98;0.0207)|Lung SC(185;0.0262)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;4.18e-05)		CTCTGCTTTCTCTGGGGAGAC	0.483000													5	56					0	0	0.014758	0	0
ARFGEF2	10564	broad.mit.edu	37	20	47611021	47611021	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr20:47611021C>T	ENST00000371917.4	+	22	3007	c.3007C>T	c.(3007-3009)Cag>Tag	p.Q1003*		NM_006420.2	NP_006411.2	Q9Y6D5	BIG2_HUMAN	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	1003					exocytosis|intracellular signal transduction|regulation of ARF protein signal transduction	cytosol|Golgi membrane	ARF guanyl-nucleotide exchange factor activity	p.Q1003E(1)		breast(7)|cervix(2)|endometrium(8)|kidney(4)|large_intestine(11)|lung(19)|ovary(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	63			BRCA - Breast invasive adenocarcinoma(12;0.00148)|Colorectal(8;0.198)			GGAGCTCGCTCAGCTGATAGG	0.493000													20	66					0	0	0.055883	0	0
CLCN3	0	broad.mit.edu	37	4	170628369	170628369	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr4:170628369C>T	ENST00000513761.1	+	11	2660	c.2101C>T	c.(2101-2103)Cag>Tag	p.Q701*	CLCN3_ENST00000347613.4_Nonsense_Mutation_p.Q701*|CLCN3_ENST00000504131.2_Nonsense_Mutation_p.Q684*|CLCN3_ENST00000360642.3_Nonsense_Mutation_p.Q674*	NM_001829.3	NP_001820.2	P51790	CLCN3_HUMAN	chloride channel, voltage-sensitive 3	701	CBS 1.				endosomal lumen acidification	cell surface|early endosome membrane|Golgi membrane|integral to membrane|late endosome membrane|transport vesicle membrane	antiporter activity|ATP binding|PDZ domain binding|protein heterodimerization activity|protein homodimerization activity|voltage-gated chloride channel activity			breast(5)|endometrium(3)|large_intestine(8)|lung(8)|ovary(1)|skin(1)|stomach(2)|upper_aerodigestive_tract(1)	29		Prostate(90;0.00601)|Renal(120;0.0183)		GBM - Glioblastoma multiforme(119;0.0233)|LUSC - Lung squamous cell carcinoma(193;0.131)		AAAAGAATCTCAGAGATTAGT	0.358000													47	154					0	0	0.048971	0	0
IRAK4	51135	broad.mit.edu	37	12	44172022	44172022	+	Silent	SNP	C	C	T			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr12:44172022C>T	ENST00000431837.1	+	7	794	c.486C>T	c.(484-486)caC>caT	p.H162H	IRAK4_ENST00000551736.1_Silent_p.H286H|IRAK4_ENST00000440781.2_Silent_p.H162H|IRAK4_ENST00000448290.2_Silent_p.H286H	NM_001145256.1|NM_001145257.1	NP_001138728.1|NP_001138729.1	Q9NWZ3	IRAK4_HUMAN	interleukin-1 receptor-associated kinase 4	286					innate immune response|MyD88-dependent toll-like receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|endosome membrane|plasma membrane	ATP binding|magnesium ion binding|protein serine/threonine kinase activity					all_cancers(12;0.00149)	Lung NSC(34;0.0804)|all_lung(34;0.181)		GBM - Glioblastoma multiforme(48;0.04)		TTTCTTGGCACATGAGATGCA	0.303000													25	73					0	0	0.037714	0	0
RRBP1	6238	broad.mit.edu	37	20	17596599	17596599	+	Missense_Mutation	SNP	C	C	A	rs116865999	byFrequency	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr20:17596599C>A	ENST00000377813.1	-	22	4226	c.3923G>T	c.(3922-3924)cGg>cTg	p.R1308L	RRBP1_ENST00000468428.1_5'UTR|RRBP1_ENST00000455029.2_Missense_Mutation_p.R649L|RRBP1_ENST00000377807.2_Missense_Mutation_p.R875L|RRBP1_ENST00000246043.4_Missense_Mutation_p.R1308L|RRBP1_ENST00000360807.4_Missense_Mutation_p.R875L			Q9P2E9	RRBP1_HUMAN	ribosome binding protein 1	1308					protein transport|translation|transmembrane transport	integral to endoplasmic reticulum membrane|ribosome	receptor activity			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(4)|lung(9)|ovary(2)|prostate(6)	28						GAGCTTCTGCCGCTGTGTCTG	0.627000													3	64					0.014758	0.0170285	0.014758	1	0
AQP7	364	broad.mit.edu	37	9	33385614	33385614	+	Missense_Mutation	SNP	A	A	T	rs140995428	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr9:33385614A>T	ENST00000541274.1	-	5	830	c.381T>A	c.(379-381)agT>agA	p.S127R	AQP7_ENST00000539936.1_3'UTR|AQP7_ENST00000537089.1_3'UTR|AQP7_ENST00000377425.4_Intron			O14520	AQP7_HUMAN	aquaporin 7	0					excretion|generation of precursor metabolites and energy	cell-cell junction|cytoplasm|integral to plasma membrane	glycerol channel activity|water channel activity			NS(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(4)|skin(2)|stomach(1)	17			LUSC - Lung squamous cell carcinoma(29;0.00788)	GBM - Glioblastoma multiforme(74;0.191)		CCACAGAAAAACTCAAAGGAA	0.632000													4	131					0	0	0.014758	0	0
SYNE2	23224	broad.mit.edu	37	14	64678781	64678781	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr14:64678781G>C	ENST00000357395.3	+	105	19125	c.7981G>C	c.(7981-7983)Gag>Cag	p.E2661Q	SYNE2_ENST00000554805.1_Missense_Mutation_p.E59Q|SYNE2_ENST00000555002.1_Missense_Mutation_p.E2910Q|SYNE2_ENST00000554584.1_Missense_Mutation_p.E6235Q|ESR2_ENST00000542956.1_Intron|SYNE2_ENST00000394768.2_Missense_Mutation_p.E2661Q|SYNE2_ENST00000344113.4_Missense_Mutation_p.E6276Q|SYNE2_ENST00000358025.3_Missense_Mutation_p.E6276Q|SYNE2_ENST00000555022.1_Missense_Mutation_p.E154Q			Q8WXH0	SYNE2_HUMAN	spectrin repeat containing, nuclear envelope 2	6276					centrosome localization|cytoskeletal anchoring at nuclear membrane|nuclear migration along microfilament|positive regulation of cell migration	cytoskeleton|filopodium membrane|focal adhesion|integral to membrane|lamellipodium membrane|mitochondrial part|nuclear outer membrane|nucleoplasm|sarcoplasmic reticulum membrane|SUN-KASH complex|Z disc	actin binding|protein binding			NS(5)|breast(17)|central_nervous_system(3)|cervix(8)|endometrium(17)|haematopoietic_and_lymphoid_tissue(2)|kidney(21)|large_intestine(34)|lung(75)|ovary(10)|pancreas(2)|prostate(8)|skin(8)|stomach(1)|upper_aerodigestive_tract(9)|urinary_tract(4)	224				all cancers(60;0.00153)|OV - Ovarian serous cystadenocarcinoma(108;0.00444)|BRCA - Breast invasive adenocarcinoma(234;0.0681)		GCACTTCTCAGAGAGTGACGC	0.542000													4	197					0	0	0.009096	0	0
C1orf216	127703	broad.mit.edu	37	1	36181503	36181503	+	Silent	SNP	G	G	A			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr1:36181503G>A	ENST00000270815.4	-	2	1190	c.420C>T	c.(418-420)ccC>ccT	p.P140P		NM_152374.1	NP_689587.1	Q8TAB5	CA216_HUMAN	chromosome 1 open reading frame 216	140										kidney(2)|lung(3)|skin(2)|urinary_tract(1)	8		Myeloproliferative disorder(586;0.0393)|all_neural(195;0.196)				GAAGGGGATCGGGAGGGCCAG	0.617000											OREG0013357	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	7	198					0	0	0.029380	0	0
RABL6	55684	broad.mit.edu	37	9	139734633	139734635	+	In_Frame_Del	DEL	AGA	AGA	-			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr9:139734633_139734635delAGA	ENST00000371675.3	+	14	2498_2500	c.1613_1615delAGA	c.(1612-1617)gag>g	p.EK538del	RABL6_ENST00000311502.7_In_Frame_Del_p.EK653del|RABL6_ENST00000432842.2_3'UTR|RABL6_ENST00000371663.4_In_Frame_Del_p.EK654del|RABL6_ENST00000357466.2_Intron					RAB, member RAS oncogene family-like 6																		CCCTCTaaggagaagaagaagaa	0.571													8	84	---	---	---	---					
LINC00840	0	broad.mit.edu	37	10	44362841	44362842	+	RNA	INS	-	-	GGGCAG	rs11283414	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr10:44362841_44362842insGGGCAG	ENST00000431737.1	+	0	1182					NR_038268.1																						ggcgggggcaagggcaggggca	0.569													4	2	---	---	---	---					
AC004231.2	0	broad.mit.edu	37	17	39130721	39130724	+	RNA	DEL	TCTT	TCTT	-	rs12941907	by1000genomes	TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chr17:39130721_39130724delTCTT	ENST00000418393.1	+	0	385																											tttctttctctctttctttctttc	0.377													6	4	---	---	---	---					
MECP2	4204	broad.mit.edu	37	X	153363113	153363113	+	Frame_Shift_Del	DEL	C	C	-			TCGA-DJ-A13R-01A-11D-A10S-08	TCGA-DJ-A13R-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3f039593-91d1-43cb-a06b-41e92f7e8d20	97808f8d-720c-41c2-ba0d-59922e48a182	g.chrX:153363113delC	ENST00000453960.2	-	1	64	c.10delG	c.(10-12)ccfs	p.A8fs	MECP2_ENST00000303391.6_5'UTR|MECP2_ENST00000407218.1_5'UTR	NM_001110792.1	NP_001104262.1	P51608	MECP2_HUMAN	methyl CpG binding protein 2 (Rett syndrome)	0					negative regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	heterochromatin|nucleus	double-stranded methylated DNA binding|protein domain specific binding|protein N-terminus binding|transcription corepressor activity			breast(2)|cervix(2)|endometrium(2)|kidney(3)|large_intestine(3)|lung(8)|prostate(2)|urinary_tract(1)	23	all_cancers(53;3.7e-16)|all_epithelial(53;3.44e-10)|all_lung(58;2.06e-07)|Lung NSC(58;2.72e-07)|all_hematologic(71;4.25e-06)|Acute lymphoblastic leukemia(192;6.56e-05)					gcggcggcggcggcggcCATT	0.776													2	4	---	---	---	---					
