Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FCER2	2208	broad.mit.edu	37	19	7754305	7754305	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr19:7754305G>A	ENST00000346664.5	-	11	952	c.740C>T	c.(739-741)cCa>cTa	p.P247L	FCER2_ENST00000597921.1_Missense_Mutation_p.P247L|FCER2_ENST00000360067.4_Missense_Mutation_p.P246L	NM_001220500.1|NM_002002.4	NP_001207429.1|NP_001993.2	P06734	FCER2_HUMAN	Fc fragment of IgE, low affinity II, receptor for (CD23)	247	C-type lectin.				positive regulation of killing of cells of other organism|positive regulation of nitric-oxide synthase 2 biosynthetic process|positive regulation of nitric-oxide synthase activity	extracellular region|integral to plasma membrane	IgE binding|integrin binding|receptor activity|sugar binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(5)|upper_aerodigestive_tract(1)	10						GGGCTCCCCTGGAGCCCAGTT	0.677000													10	7					0	0	0.069234	0	0
RAB11FIP5	26056	broad.mit.edu	37	2	73315689	73315689	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr2:73315689G>A	ENST00000258098.6	-	3	1297	c.1057C>T	c.(1057-1059)Cgg>Tgg	p.R353W	RAB11FIP5_ENST00000493523.2_5'UTR	NM_015470.2	NP_056285.1	Q9BXF6	RFIP5_HUMAN	RAB11 family interacting protein 5 (class I)	353					protein transport	mitochondrial outer membrane|recycling endosome membrane	gamma-tubulin binding			biliary_tract(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(3)|lung(9)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	23						CTGCGGTGCCGCACAGGGCCC	0.627000													4	82					0	0	0.009096	0	0
MYO15A	51168	broad.mit.edu	37	17	18057452	18057452	+	Missense_Mutation	SNP	A	A	G			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr17:18057452A>G	ENST00000205890.5	+	44	8434	c.8096A>G	c.(8095-8097)tAc>tGc	p.Y2699C	MYO15A_ENST00000418233.3_5'UTR|MYO15A_ENST00000585180.1_5'UTR	NM_016239.3	NP_057323.3	Q9UKN7	MYO15_HUMAN	myosin XVA	2699	Tail.				sensory perception of sound	cytoplasm|myosin complex|stereocilium	actin binding|ATP binding|calmodulin binding|motor activity			breast(5)|central_nervous_system(2)|endometrium(17)|kidney(3)|large_intestine(16)|lung(27)|ovary(3)|pancreas(1)|prostate(6)|skin(13)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	99	all_neural(463;0.228)					CAGGTGTTTTACCCCAAGGAC	0.637000													4	108					0	0	0.014758	0	0
MAGEB6	158809	broad.mit.edu	37	X	26212809	26212809	+	Silent	SNP	G	G	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chrX:26212809G>A	ENST00000379034.1	+	2	995	c.846G>A	c.(844-846)ctG>ctA	p.L282L		NM_173523.2	NP_775794.2	Q8N7X4	MAGB6_HUMAN	melanoma antigen family B, 6	282	MAGE.									breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|liver(1)|lung(18)|ovary(3)|prostate(2)	33						ATAATGCGCTGCCGAAGTCGG	0.542000													8	250					0	0	0.038147	0	0
BCL9	607	broad.mit.edu	37	1	147091712	147091712	+	Missense_Mutation	SNP	G	G	T			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr1:147091712G>T	ENST00000234739.3	+	8	2491	c.1751G>T	c.(1750-1752)aGa>aTa	p.R584I		NM_004326.2	NP_004317.2	O00512	BCL9_HUMAN	B-cell CLL/lymphoma 9	584	Pro-rich.				Wnt receptor signaling pathway	nucleus	protein binding			breast(1)|large_intestine(2)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	7	all_hematologic(923;0.115)					CCTGCATCTAGACCAGGTCTT	0.552000			T	"""IGH@, IGL@"""	B-ALL								6	213					5.9392e-07	8.31488e-07	0.021553	1	0
GOT2	2806	broad.mit.edu	37	16	58743338	58743338	+	Missense_Mutation	SNP	C	C	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr16:58743338C>A	ENST00000245206.5	-	9	1281	c.1153G>T	c.(1153-1155)Ggg>Tgg	p.G385W	GOT2_ENST00000434819.2_Missense_Mutation_p.G342W	NM_002080.2	NP_002071.2	P00505	AATM_HUMAN	glutamic-oxaloacetic transaminase 2, mitochondrial	385					aspartate catabolic process|fatty acid transport|gluconeogenesis|response to ethanol	mitochondrial matrix|plasma membrane	L-aspartate:2-oxoglutarate aminotransferase activity|protein binding|pyridoxal phosphate binding			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(3)|large_intestine(2)|lung(8)|prostate(2)|skin(1)	22					L-Aspartic Acid(DB00128)|L-Glutamic Acid(DB00142)|Pyridoxal Phosphate(DB00114)	GGCTTTAGCCCTGTGAAACAG	0.458000													4	170					0.00909568	0.0112358	0.009096	1	0
HPD	3242	broad.mit.edu	37	12	122292689	122292689	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr12:122292689C>T	ENST00000543163.1	-	8	662	c.217G>A	c.(217-219)Gaa>Aaa	p.E73K	HPD_ENST00000289004.4_Missense_Mutation_p.E112K	NM_001171993.1	NP_001165464.1	P32754	HPPD_HUMAN	4-hydroxyphenylpyruvate dioxygenase	112					L-phenylalanine catabolic process|tyrosine catabolic process	cytosol	4-hydroxyphenylpyruvate dioxygenase activity|metal ion binding			breast(1)|cervix(1)|kidney(1)|large_intestine(6)|lung(8)|urinary_tract(1)	18	all_neural(191;0.0684)|Medulloblastoma(191;0.0922)			OV - Ovarian serous cystadenocarcinoma(86;0.000105)|Epithelial(86;0.000352)|BRCA - Breast invasive adenocarcinoma(302;0.225)	Nitisinone(DB00348)	GCGCCCCGTTCCCGTGCTTTC	0.597000													55	65					0	0	0.139131	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				42	79					0	0	0.111260	0	0
SLITRK1	114798	broad.mit.edu	37	13	84453858	84453858	+	Silent	SNP	G	G	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr13:84453858G>A	ENST00000377084.2	-	1	2670	c.1785C>T	c.(1783-1785)aaC>aaT	p.N595N		NM_052910.1	NP_443142.1	Q96PX8	SLIK1_HUMAN	SLIT and NTRK-like family, member 1	595						integral to membrane				NS(2)|breast(1)|central_nervous_system(2)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(22)|liver(1)|lung(36)|ovary(4)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	80	Medulloblastoma(90;0.18)	Breast(118;0.212)		GBM - Glioblastoma multiforme(99;0.07)		ACCCAGTGCTGTTTTTACTGT	0.542000													4	62					0	0	0.014758	0	0
NUMA1	0	broad.mit.edu	37	11	71734181	71734181	+	Missense_Mutation	SNP	T	T	C	rs140051813	byFrequency	TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr11:71734181T>C	ENST00000393695.3	-	6	552	c.221A>G	c.(220-222)cAt>cGt	p.H74R	NUMA1_ENST00000358965.6_Missense_Mutation_p.H74R|NUMA1_ENST00000351960.6_Missense_Mutation_p.H74R	NM_006185.2	NP_006176.2	Q14980	NUMA1_HUMAN	nuclear mitotic apparatus protein 1	74					G2/M transition of mitotic cell cycle|mitotic anaphase|nucleus organization	chromosome|cytosol|nucleoplasm|spindle microtubule|spindle pole	protein binding|structural molecule activity			central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(12)|lung(20)|ovary(5)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(3)	65						GGAAGAGGGATGTTTTCGATT	0.493000			T	RARA	APL								63	97					0	0	0.139131	0	0
NLRP1	22861	broad.mit.edu	37	17	5487102	5487102	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr17:5487102G>A	ENST00000345221.3	-	1	730	c.176C>T	c.(175-177)gCt>gTt	p.A59V	NLRP1_ENST00000571307.1_5'UTR|NLRP1_ENST00000262467.5_Missense_Mutation_p.A59V|NLRP1_ENST00000572272.1_Missense_Mutation_p.A59V|NLRP1_ENST00000577119.1_Missense_Mutation_p.A59V|NLRP1_ENST00000354411.3_Missense_Mutation_p.A59V|NLRP1_ENST00000269280.4_Missense_Mutation_p.A59V	NM_014922.4|NM_033004.3|NM_033007.3	NP_055737.1|NP_127497.1|NP_127500.1	Q9C000	NALP1_HUMAN	NLR family, pyrin domain containing 1	59	DAPIN.				defense response to bacterium|induction of apoptosis|neuron apoptosis|positive regulation of interleukin-1 beta secretion|response to muramyl dipeptide	cytoplasm|NALP1 inflammasome complex|nucleus	ATP binding|caspase activator activity|enzyme binding|protein domain specific binding			breast(4)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(2)|large_intestine(17)|liver(5)|lung(17)|ovary(1)|prostate(3)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	65		Colorectal(1115;3.48e-05)				CCCATACTGAGCCACCAGGTA	0.637000													2	6					0	0	0.115264	0	0
SLC38A4	55089	broad.mit.edu	37	12	47168909	47168909	+	Missense_Mutation	SNP	A	A	T			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr12:47168909A>T	ENST00000447411.1	-	13	1428	c.1222T>A	c.(1222-1224)Tta>Ata	p.L408I	SLC38A4_ENST00000266579.4_Missense_Mutation_p.L408I	NM_001143824.1	NP_001137296.1	Q969I6	S38A4_HUMAN	solute carrier family 38, member 4	408					cellular nitrogen compound metabolic process|sodium ion transport	integral to membrane|plasma membrane	amino acid transmembrane transporter activity|symporter activity			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(4)|lung(6)|ovary(3)|skin(1)	21	Lung SC(27;0.192)|Renal(347;0.236)					GGGATGTCTAATGTATACACT	0.438000													60	95					0	0	0.139131	0	0
ZNF607	84775	broad.mit.edu	37	19	38190685	38190685	+	Missense_Mutation	SNP	C	C	A			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr19:38190685C>A	ENST00000355202.4	-	5	942	c.347G>T	c.(346-348)tGt>tTt	p.C116F	ZNF607_ENST00000395835.3_Missense_Mutation_p.C115F|CTD-2528L19.4_ENST00000586606.2_Splice_Site	NM_032689.4	NP_116078.4	Q96SK3	ZN607_HUMAN	zinc finger protein 607	116					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			cervix(1)|endometrium(3)|kidney(3)|large_intestine(11)|lung(8)|urinary_tract(1)	27			UCEC - Uterine corpus endometrioid carcinoma (49;0.0775)			ACATTGCTTACACTCATATGG	0.368000													88	132					4.37026e-21	6.55538e-21	0.139131	1	0
C11orf63	79864	broad.mit.edu	37	11	122774973	122774973	+	Missense_Mutation	SNP	G	G	T			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr11:122774973G>T	ENST00000227349.2	+	3	982	c.685G>T	c.(685-687)Gtg>Ttg	p.V229L	C11orf63_ENST00000531316.1_Missense_Mutation_p.V229L|C11orf63_ENST00000307257.6_Missense_Mutation_p.V229L	NM_024806.2	NP_079082.2	Q6NUN7	CK063_HUMAN	chromosome 11 open reading frame 63	229										breast(1)|central_nervous_system(1)|endometrium(4)|kidney(4)|large_intestine(13)|lung(14)|ovary(3)|pancreas(1)|prostate(2)|skin(1)|soft_tissue(1)|stomach(1)|upper_aerodigestive_tract(1)	47		Breast(109;0.00249)|Lung NSC(97;0.0177)|all_lung(97;0.018)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;5.34e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0311)		TTCTCCGTACGTGAAGAGCTC	0.512000													5	181					1.23904e-05	1.62624e-05	0.014758	1	0
SDHAP1	0	broad.mit.edu	37	3	195711343	195711344	+	RNA	INS	-	-	T			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr3:195711343_195711344insT	ENST00000427841.1	-	0	585					NR_003264.2																						AAAGACTTCTCTGTGAGCTTTG	0.381													4	6	---	---	---	---					
RP11-122F24.1	0	broad.mit.edu	37	5	7045029	7045029	+	RNA	DEL	T	T	-			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr5:7045029delT	ENST00000512838.1	+	0	154																											tctttctttcttttttttttt	0.463													2	4	---	---	---	---					
RP11-521C20.2	0	broad.mit.edu	37	15	40369522	40369529	+	RNA	DEL	GGAAGGAA	GGAAGGAA	-			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr15:40369522_40369529delGGAAGGAA	ENST00000560376.1	-	0	47																											agggatggagggaaggaaggaaggaagg	0.476													2	4	---	---	---	---					
BFAR	51283	broad.mit.edu	37	16	14761616	14761617	+	Frame_Shift_Del	DEL	TT	TT	-			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr16:14761616_14761617delTT	ENST00000261658.2	+	8	1562_1563	c.1285_1286delTT	c.(1285-1287)tfs	p.F429fs	BFAR_ENST00000426842.2_Frame_Shift_Del_p.F301fs|BFAR_ENST00000563971.1_Frame_Shift_Del_p.F304fs|BFAR_ENST00000563082.1_3'UTR	NM_016561.2	NP_057645.1	Q9NZS9	BFAR_HUMAN	bifunctional apoptosis regulator	429					anti-apoptosis|apoptosis	endoplasmic reticulum membrane|integral to plasma membrane|membrane fraction	structural molecule activity|zinc ion binding			endometrium(4)|kidney(1)|large_intestine(2)|lung(1)|ovary(2)|skin(1)	11						GGCCCTGTACTTTAACCCAATT	0.495													9	247	---	---	---	---					
PKD1L2	114780	broad.mit.edu	37	16	81201441	81201441	+	RNA	DEL	G	G	-	rs35726804		TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr16:81201441delG	ENST00000533478.1	-	0	1149				PKD1L2_ENST00000525539.1_RNA	NM_001278425.1	NP_001265354.1	Q7Z442	PK1L2_HUMAN	polycystic kidney disease 1-like 2						neuropeptide signaling pathway	integral to membrane	calcium ion binding|ion channel activity|sugar binding			breast(2)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(9)|lung(20)|ovary(2)|pancreas(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	44						tctgcaagatggggggggaaa	0.567													6	1	---	---	---	---					
FAM27L	284123	broad.mit.edu	37	17	21825841	21825842	+	RNA	DEL	TG	TG	-			TCGA-DJ-A13T-01A-11D-A10S-08	TCGA-DJ-A13T-10A-01D-A10S-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	a8acbdbd-68b9-4fb3-97c8-90b290a1f098	8f7b0d92-d0ba-4881-a695-6fb6fed6d455	g.chr17:21825841_21825842delTG	ENST00000426869.3	+	0	278					NR_028336.1				family with sequence similarity 27-like											central_nervous_system(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(7)|prostate(1)	14				UCEC - Uterine corpus endometrioid carcinoma (53;0.11)|BRCA - Breast invasive adenocarcinoma(1;0.00463)		tcggtttgtatgtgtgtgtgtg	0.500													4	6	---	---	---	---					
