Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
KCND3	3752	broad.mit.edu	37	1	112524826	112524826	+	Missense_Mutation	SNP	T	T	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr1:112524826T>C	ENST00000369697.1	-	1	592	c.523A>G	c.(523-525)Aac>Gac	p.N175D	KCND3_ENST00000315987.2_Missense_Mutation_p.N175D|KCND3_ENST00000302127.4_Missense_Mutation_p.N175D			Q9UK17	KCND3_HUMAN	potassium voltage-gated channel, Shal-related subfamily, member 3	175						sarcolemma|voltage-gated potassium channel complex	A-type (transient outward) potassium channel activity|metal ion binding			NS(1)|breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(16)|lung(9)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(4)|urinary_tract(2)	49		all_cancers(81;8.52e-06)|all_epithelial(167;5.65e-06)|all_lung(203;2.72e-05)|Lung NSC(69;4.56e-05)		all cancers(265;0.056)|Lung(183;0.0576)|Colorectal(144;0.1)|Epithelial(280;0.104)|COAD - Colon adenocarcinoma(174;0.222)|LUSC - Lung squamous cell carcinoma(189;0.231)		GTGTGGGGGTTCTCGAAGGCC	0.627000													9	44					0	0	1	0	0
POM121L9P	0	broad.mit.edu	37	22	24659813	24659813	+	RNA	SNP	C	C	T			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr22:24659813C>T	ENST00000414583.2	+	0	3338					NR_003714.1																						ATCTGCGCACCCGGAGGTGGG	0.607000													3	8					0	0	1	0	0
MRPS18C	51023	broad.mit.edu	37	4	84377236	84377236	+	Silent	SNP	C	C	T			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr4:84377236C>T	ENST00000295491.4	+	1	119	c.6C>T	c.(4-6)gcC>gcT	p.A2A	MRPS18C_ENST00000507349.1_Silent_p.A2A|MRPS18C_ENST00000507019.1_Silent_p.A2A	NM_016067.2	NP_057151.1	Q9Y3D5	RT18C_HUMAN	mitochondrial ribosomal protein S18C	2					translation	mitochondrial small ribosomal subunit	structural constituent of ribosome			endometrium(1)|kidney(1)|large_intestine(2)|lung(1)	5		Hepatocellular(203;0.114)				GAACCATGGCCGCTGTGGTTG	0.562000													37	169					0	0	1	0	0
SNX20	124460	broad.mit.edu	37	16	50707544	50707544	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr16:50707544G>A	ENST00000330943.4	-	4	895	c.724C>T	c.(724-726)Cgc>Tgc	p.R242C	SNX20_ENST00000423026.2_Intron|SNX20_ENST00000300590.3_Intron	NM_182854.2	NP_878274.1	Q7Z614	SNX20_HUMAN	sorting nexin 20	242					cell communication|protein transport	endosome membrane|nucleus|plasma membrane	phosphatidylinositol binding|protein binding			kidney(1)|large_intestine(3)|lung(5)|ovary(2)|prostate(1)|skin(2)|stomach(1)	15						TCGGCGGGGCGGTCGAGGTCG	0.756000													5	18					0	0	1	0	0
POM121L9P	0	broad.mit.edu	37	22	24659809	24659809	+	RNA	SNP	G	G	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr22:24659809G>A	ENST00000414583.2	+	0	3334					NR_003714.1																						CCCTATCTGCGCACCCGGAGG	0.612000													3	10					0	0	1	0	0
KIAA0391	9692	broad.mit.edu	37	14	35742769	35742769	+	Silent	SNP	A	A	G			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr14:35742769A>G	ENST00000557565.1	+	8	2130	c.1749A>G	c.(1747-1749)acA>acG	p.T583T	KIAA0391_ENST00000250377.7_Silent_p.T488T|KIAA0391_ENST00000321130.10_Silent_p.T567T|KIAA0391_ENST00000604948.1_Silent_p.T488T|KIAA0391_ENST00000603544.1_Silent_p.T567T|KIAA0391_ENST00000534898.4_Silent_p.T583T|KIAA0391_ENST00000605870.1_Silent_p.T211T			O15091	MRRP3_HUMAN	KIAA0391	583					tRNA processing	mitochondrion				central_nervous_system(1)|endometrium(4)|large_intestine(2)|lung(5)|skin(1)|upper_aerodigestive_tract(1)	14	Breast(36;0.0545)|Hepatocellular(127;0.158)|Prostate(35;0.184)		Lung(238;2.93e-05)|LUAD - Lung adenocarcinoma(48;3.86e-05)|Epithelial(34;0.0114)|all cancers(34;0.0277)	GBM - Glioblastoma multiforme(112;0.0593)		ACCAAAAGACATAGAGATTCT	0.453000													4	41					0	0	1	0	0
WRN	7486	broad.mit.edu	37	8	30998961	30998961	+	Missense_Mutation	SNP	G	G	A	rs140768346	byFrequency	TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr8:30998961G>A	ENST00000298139.5	+	25	3232	c.2983G>A	c.(2983-2985)Gcc>Acc	p.A995T		NM_000553.4	NP_000544.2	Q14191	WRN_HUMAN	Werner syndrome, RecQ helicase-like	995					base-excision repair|cellular response to starvation|DNA recombination|DNA synthesis involved in DNA repair|multicellular organismal aging|nucleolus to nucleoplasm transport|positive regulation of hydrolase activity|regulation of apoptosis|replication fork processing|response to oxidative stress|response to UV-C|telomere maintenance	centrosome|nucleolus|nucleoplasm	3'-5' exonuclease activity|ATP binding|ATP-dependent 3'-5' DNA helicase activity|bubble DNA binding|four-way junction helicase activity|G-quadruplex DNA binding|magnesium ion binding|manganese ion binding|protein complex binding|protein homodimerization activity|Y-form DNA binding			central_nervous_system(2)|endometrium(4)|kidney(4)|large_intestine(13)|lung(28)|ovary(3)|skin(3)|upper_aerodigestive_tract(3)	60		Breast(100;0.195)		KIRC - Kidney renal clear cell carcinoma(542;0.147)|Kidney(114;0.176)|Colorectal(111;0.192)		TCAGCGTCTTGCCGATCAATA	0.378000			"""Mis, N, F, S"""			"""osteosarcoma, meningioma, others"""		Genes defective in diseases associated with sensitivity to DNA damaging agents	Werner syndrome				4	51					0	0	1	0	0
RNF215	200312	broad.mit.edu	37	22	30776280	30776280	+	Silent	SNP	G	G	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr22:30776280G>A	ENST00000382363.3	-	6	929	c.855C>T	c.(853-855)ctC>ctT	p.L285L		NM_001017981.1	NP_001017981.1	Q9Y6U7	RN215_HUMAN	ring finger protein 215	285						integral to membrane	zinc ion binding			central_nervous_system(1)|endometrium(2)|large_intestine(1)|lung(2)	6						CCTGGCCTCCGAGCTCCCGCT	0.687000													9	47					0	0	1	0	0
CCDC88B	283234	broad.mit.edu	37	11	64124622	64124622	+	Missense_Mutation	SNP	G	G	A	rs61886888	by1000genomes	TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr11:64124622G>A	ENST00000359902.2	+	14	1951	c.1801G>A	c.(1801-1803)Gga>Aga	p.G601R	CCDC88B_ENST00000463837.1_3'UTR|CCDC88B_ENST00000356786.5_3'UTR|CCDC88B_ENST00000301897.4_3'UTR			A6NC98	CC88B_HUMAN	coiled-coil domain containing 88B	1424					microtubule cytoskeleton organization	cytoplasm	microtubule binding			endometrium(1)|kidney(2)|large_intestine(1)|lung(12)|ovary(3)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	27						GAGTGTCAGCGGAGGCCCCAG	0.667000													4	43					0	0	1	0	0
OR51E2	81285	broad.mit.edu	37	11	4703767	4703767	+	Missense_Mutation	SNP	A	A	G			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr11:4703767A>G	ENST00000396950.3	-	2	414	c.175T>C	c.(175-177)Tac>Cac	p.Y59H		NM_030774.3	NP_110401.1	Q9H255	O51E2_HUMAN	olfactory receptor, family 51, subfamily E, member 2	59					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(12)|ovary(2)|prostate(1)|skin(3)	23		Medulloblastoma(188;0.0075)|Breast(177;0.0461)|all_neural(188;0.0577)		Epithelial(150;3e-12)|BRCA - Breast invasive adenocarcinoma(625;0.00476)|LUSC - Lung squamous cell carcinoma(625;0.2)		AGAAAGAGGTACATCGGAGCG	0.512000													7	86					0	0	1	0	0
XYLT2	64132	broad.mit.edu	37	17	48431804	48431804	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr17:48431804C>T	ENST00000017003.2	+	3	713	c.664C>T	c.(664-666)Caa>Taa	p.Q222*	XYLT2_ENST00000507602.1_Nonsense_Mutation_p.Q222*	NM_022167.2	NP_071450.2	Q9H1B5	XYLT2_HUMAN	xylosyltransferase II	222					glycosaminoglycan biosynthetic process	endoplasmic reticulum membrane|Golgi membrane|integral to membrane	acetylglucosaminyltransferase activity|protein xylosyltransferase activity			endometrium(2)|kidney(2)|large_intestine(4)|pancreas(1)|prostate(2)|urinary_tract(1)	12	Breast(11;7.18e-19)					GGATGAGAGCCAAGCCCAGCA	0.657000													7	40					0	0	1	0	0
ZCCHC10	54819	broad.mit.edu	37	5	132342584	132342584	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr5:132342584G>C	ENST00000324170.3	-	2	136	c.70C>G	c.(70-72)Cag>Gag	p.Q24E	ZCCHC10_ENST00000508080.1_5'UTR|ZCCHC10_ENST00000355372.2_Missense_Mutation_p.Q46E|ZCCHC10_ENST00000513848.1_Missense_Mutation_p.Q24E|ZCCHC10_ENST00000513541.1_Missense_Mutation_p.Q46E|ZCCHC10_ENST00000509008.1_Missense_Mutation_p.Q24E|ZCCHC10_ENST00000509437.1_Missense_Mutation_p.Q46E	NM_017665.1	NP_060135.1	Q8TBK6	ZCH10_HUMAN	zinc finger, CCHC domain containing 10	46							nucleic acid binding|zinc ion binding			skin(1)	1			KIRC - Kidney renal clear cell carcinoma(527;0.0186)|Kidney(363;0.0365)			AAGCATTTCTGACATCTTACA	0.338000													6	17					0	0	1	0	0
TAF1L	138474	broad.mit.edu	37	9	32634427	32634427	+	Missense_Mutation	SNP	C	C	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr9:32634427C>A	ENST00000242310.4	-	1	1240	c.1151G>T	c.(1150-1152)gGc>gTc	p.G384V	RP11-555J4.4_ENST00000430787.1_RNA	NM_153809.2	NP_722516.1	Q8IZX4	TAF1L_HUMAN	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like	384					male meiosis|positive regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter|transcription initiation, DNA-dependent	transcription factor TFIID complex	DNA binding|histone acetyltransferase activity|protein serine/threonine kinase activity|TBP-class protein binding			breast(6)|central_nervous_system(4)|endometrium(14)|kidney(11)|large_intestine(32)|liver(2)|lung(68)|ovary(2)|pancreas(2)|prostate(7)|skin(9)|stomach(1)|upper_aerodigestive_tract(1)	159			LUSC - Lung squamous cell carcinoma(29;0.0181)	GBM - Glioblastoma multiforme(74;0.00301)		CAGTTTGAAGCCATAGTCAAA	0.463000													35	146					1.36615e-20	1.45428e-20	1	1	0
UNC79	57578	broad.mit.edu	37	14	94158128	94158128	+	Missense_Mutation	SNP	G	G	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr14:94158128G>A	ENST00000553484.1	+	48	7643	c.7489G>A	c.(7489-7491)Gcg>Acg	p.A2497T	UNC79_ENST00000256339.4_Missense_Mutation_p.A2298T|UNC79_ENST00000555664.1_Missense_Mutation_p.A2436T|UNC79_ENST00000393151.2_Missense_Mutation_p.A2475T			Q9P2D8	UNC79_HUMAN	unc-79 homolog (C. elegans)	2475						integral to membrane				breast(3)|cervix(2)|endometrium(10)|kidney(7)|large_intestine(18)|liver(1)|lung(64)|ovary(1)|prostate(5)|skin(3)|urinary_tract(4)	118						CCTCTTCCACGCGTTCATCTT	0.527000													9	93					0	0	1	0	0
ARCN1	372	broad.mit.edu	37	11	118455206	118455206	+	Missense_Mutation	SNP	C	C	T			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr11:118455206C>T	ENST00000359415.4	+	6	953	c.788C>T	c.(787-789)cCc>cTc	p.P263L	ARCN1_ENST00000264028.4_Missense_Mutation_p.P222L|ARCN1_ENST00000534182.2_Intron|ARCN1_ENST00000392859.3_Missense_Mutation_p.P134L			P48444	COPD_HUMAN	archain 1	222					COPI coating of Golgi vesicle|intracellular protein transport|retrograde vesicle-mediated transport, Golgi to ER	clathrin adaptor complex|COPI vesicle coat|cytosol				endometrium(1)|kidney(2)|large_intestine(3)|lung(4)|ovary(2)|urinary_tract(1)	13	all_hematologic(175;0.0349)	Medulloblastoma(222;0.0425)|all_hematologic(192;0.0564)|all_neural(223;0.234)		BRCA - Breast invasive adenocarcinoma(274;3.28e-05)		CCTTCAGGCCCCAGCAAGGCT	0.393000													5	29					0	0	1	0	0
C12orf66	144577	broad.mit.edu	37	12	64587880	64587880	+	Silent	SNP	G	G	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr12:64587880G>A	ENST00000311915.8	-	3	1107	c.1080C>T	c.(1078-1080)caC>caT	p.H360H	C12orf66_ENST00000398055.3_Silent_p.H360H|C12orf66_ENST00000544871.1_Silent_p.H307H			Q96MD2	CL066_HUMAN	chromosome 12 open reading frame 66	360										central_nervous_system(1)|large_intestine(1)|lung(2)|ovary(1)	5						CATTGGGCCAGTGCATGACTG	0.522000													9	112					0	0	1	0	0
ZNF438	220929	broad.mit.edu	37	10	31138963	31138963	+	Missense_Mutation	SNP	T	T	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr10:31138963T>C	ENST00000538351.1	-	7	978	c.224A>G	c.(223-225)tAt>tGt	p.Y75C	ZNF438_ENST00000331737.6_Missense_Mutation_p.Y114C|ZNF438_ENST00000444692.2_Missense_Mutation_p.Y114C|ZNF438_ENST00000361310.3_Missense_Mutation_p.Y124C|ZNF438_ENST00000452305.1_Missense_Mutation_p.Y114C|ZNF438_ENST00000436087.2_Missense_Mutation_p.Y124C|ZNF438_ENST00000442986.1_Missense_Mutation_p.Y124C|ZNF438_ENST00000413025.1_Missense_Mutation_p.Y124C|ZNF438_ENST00000375311.1_Intron	NM_001143769.1	NP_001137241.1	Q7Z4V0	ZN438_HUMAN	zinc finger protein 438	124					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(3)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(3)|lung(15)|ovary(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	35		Prostate(175;0.0587)				AGGGGGTTGATATCTAGGAAT	0.448000													7	100					0	0	1	0	0
TMEM203	94107	broad.mit.edu	37	9	140099754	140099754	+	Missense_Mutation	SNP	T	T	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr9:140099754T>C	ENST00000343666.5	-	1	336	c.113A>G	c.(112-114)gAt>gGt	p.D38G	TMEM203_ENST00000537254.1_Missense_Mutation_p.D38G	NM_053045.1	NP_444273.1	Q969S6	TM203_HUMAN	transmembrane protein 203	38						integral to membrane				central_nervous_system(1)|kidney(1)	2	all_cancers(76;0.0926)		STAD - Stomach adenocarcinoma(284;0.0698)	OV - Ovarian serous cystadenocarcinoma(145;6.37e-05)|Epithelial(140;0.00057)		GACCAGGCCATCCACACGCAG	0.637000													3	20					0	0	1	0	0
RAI14	26064	broad.mit.edu	37	5	34808710	34808710	+	Missense_Mutation	SNP	C	C	A			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr5:34808710C>A	ENST00000265109.3	+	7	688	c.401C>A	c.(400-402)gCt>gAt	p.A134D	RAI14_ENST00000512629.1_Missense_Mutation_p.A134D|RAI14_ENST00000397449.1_Missense_Mutation_p.A127D|RAI14_ENST00000503673.1_Missense_Mutation_p.A134D|RAI14_ENST00000507276.1_3'UTR|RAI14_ENST00000506376.1_Missense_Mutation_p.A126D|RAI14_ENST00000515799.1_Missense_Mutation_p.A137D|RAI14_ENST00000428746.2_Missense_Mutation_p.A134D	NM_001145522.1|NM_015577.2	NP_001138994.1|NP_056392.2	Q9P0K7	RAI14_HUMAN	retinoic acid induced 14	134						cell cortex|cytoskeleton	protein binding			breast(2)|central_nervous_system(1)|endometrium(2)|kidney(4)|large_intestine(19)|lung(22)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	56	all_lung(31;0.000191)					TGCCTTCAAGCTGTGCAGATT	0.478000													6	37					3.09899e-07	3.19583e-07	1	1	0
PRDM15	63977	broad.mit.edu	37	21	43259762	43259762	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr21:43259762G>C	ENST00000422911.1	-	7	1053	c.952C>G	c.(952-954)Cta>Gta	p.L318V	PRDM15_ENST00000447207.2_Missense_Mutation_p.L281V|PRDM15_ENST00000538201.1_Missense_Mutation_p.L281V|PRDM15_ENST00000398548.1_Missense_Mutation_p.L318V|PRDM15_ENST00000269844.3_Missense_Mutation_p.L647V			P57071	PRD15_HUMAN	PR domain containing 15	647					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(2)|breast(1)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(9)|lung(11)|ovary(3)|skin(2)|stomach(2)|urinary_tract(1)	43						ACGATGACTAGAGGCTGCTCA	0.617000													12	253					0	0	1	0	0
VMP1	81671	broad.mit.edu	37	17	57915689	57915689	+	Missense_Mutation	SNP	G	G	C			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr17:57915689G>C	ENST00000262291.4	+	11	1318	c.1008G>C	c.(1006-1008)aaG>aaC	p.K336N	VMP1_ENST00000588617.1_3'UTR|VMP1_ENST00000539763.1_Missense_Mutation_p.K144N|VMP1_ENST00000537567.1_Missense_Mutation_p.K202N|VMP1_ENST00000545362.1_Missense_Mutation_p.K280N|VMP1_ENST00000536180.1_Missense_Mutation_p.K239N	NM_030938.3	NP_112200.2	Q96GC9	VMP1_HUMAN	vacuole membrane protein 1	336					autophagy|cell adhesion	endoplasmic reticulum|ER-Golgi intermediate compartment membrane|integral to membrane|plasma membrane|vacuolar membrane				breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(5)|lung(4)|skin(2)	16						CTCTGCAGAAGCCATTTCAGG	0.493000													10	52					0	0	1	0	0
ITIH4	3700	broad.mit.edu	37	3	52852225	52852225	+	Splice_Site	DEL	G	G	-			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr3:52852225delG	ENST00000346281.5	-	18	2149	c.2089_splice	c.e18-1	p.A697_splice	ITIH4_ENST00000266041.4_Intron|ITIH4_ENST00000485816.1_Intron|ITIH4_ENST00000406595.1_Intron	NM_001166449.1	NP_001159921.1	Q14624	ITIH4_HUMAN	inter-alpha-trypsin inhibitor heavy chain family, member 4	725					acute-phase response|hyaluronan metabolic process	extracellular region	serine-type endopeptidase inhibitor activity			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(4)|large_intestine(3)|lung(9)|ovary(3)|pancreas(1)|prostate(3)|skin(4)|upper_aerodigestive_tract(1)	30				BRCA - Breast invasive adenocarcinoma(193;7e-05)|Kidney(197;0.000656)|KIRC - Kidney renal clear cell carcinoma(197;0.000794)|OV - Ovarian serous cystadenocarcinoma(275;0.0496)		AGGAAGGGCAGGCTGGGGGCA	0.602													8	59	---	---	---	---					
SDHAP1	0	broad.mit.edu	37	3	195711343	195711344	+	RNA	INS	-	-	T			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr3:195711343_195711344insT	ENST00000427841.1	-	0	585					NR_003264.2																						AAAGACTTCTCTGTGAGCTTTG	0.381													5	6	---	---	---	---					
MAFA	389692	broad.mit.edu	37	8	144511954	144511956	+	In_Frame_Del	DEL	TGG	TGG	-			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr8:144511954_144511956delTGG	ENST00000333480.2	-	1	620_622	c.621_623delCCA	c.(619-624)cat>ca	p.HH207del	MAFA_ENST00000528185.1_5'UTR	NM_201589.3	NP_963883.2	Q8NHW3	MAFA_HUMAN	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	207	His-rich.				insulin secretion|nitric oxide mediated signal transduction|response to glucose stimulus	nucleus	protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity	p.H208delH(3)		breast(1)|lung(1)|upper_aerodigestive_tract(2)	4	all_cancers(97;7.39e-11)|all_epithelial(106;5.44e-09)|Lung NSC(106;0.000167)|all_lung(105;0.000459)|Ovarian(258;0.0212)|Acute lymphoblastic leukemia(118;0.155)		Colorectal(110;0.107)|BRCA - Breast invasive adenocarcinoma(115;0.237)			CGCGCCGCCAtggtggtggtggt	0.744										HNSCC(29;0.082)			4	3	---	---	---	---					
IGHJ6	0	broad.mit.edu	37	14	106329450	106329451	+	RNA	INS	-	-	ACC	rs74454466	by1000genomes	TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr14:106329450_106329451insACC	ENST00000390560.2	-	0	17_18																											CAGACGTCCATGTAGTAGTAGT	0.540													9	69	---	---	---	---					
AP001347.6	0	broad.mit.edu	37	21	15436915	15436915	+	RNA	DEL	G	G	-			TCGA-DJ-A3VK-01A-11D-A23M-08	TCGA-DJ-A3VK-10A-01D-A23K-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f8f26be4-e2af-4f97-a57f-ed36defb74b5	d839b4e3-7b94-49f6-9dfc-6e9b56e6e2a9	g.chr21:15436915delG	ENST00000428809.1	+	0	177																											CCCCTGGGACGGGGGCCTTGG	0.687													3	5	---	---	---	---					
