Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PRDM8	56978	broad.mit.edu	37	4	81124557	81124557	+	Silent	SNP	C	C	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr4:81124557C>T	ENST00000339711.4	+	10	3172	c.1941C>T	c.(1939-1941)caC>caT	p.H647H	PRDM8_ENST00000504452.1_Silent_p.H647H|PRDM8_ENST00000415738.2_Silent_p.H647H	NM_020226.3	NP_064611.3	Q9NQV8	PRDM8_HUMAN	PR domain containing 8	647					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(2)|skin(2)	10						TGAGGTCGCACCACAAAAAGG	0.597000													13	26					0	0	1	0	0
DCAF12	25853	broad.mit.edu	37	9	34107509	34107509	+	Missense_Mutation	SNP	C	C	A			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr9:34107509C>A	ENST00000361264.4	-	3	729	c.388G>T	c.(388-390)Gac>Tac	p.D130Y	DCAF12_ENST00000463286.1_5'UTR	NM_015397.3	NP_056212.1	Q5T6F0	DCA12_HUMAN	DDB1 and CUL4 associated factor 12	130						centrosome|CUL4 RING ubiquitin ligase complex				breast(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(4)|prostate(1)	11						GGCTCCCGGTCTTTCAGAATG	0.488000													12	57					0.00136819	0.00152022	1	1	0
PCDHB10	0	broad.mit.edu	37	5	140573713	140573713	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr5:140573713C>T	ENST00000239446.4	+	1	1772	c.1588C>T	c.(1588-1590)Cgc>Tgc	p.R530C		NM_018930.3	NP_061753.1	Q9UN67	PCDBA_HUMAN		530	Cadherin 5.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding			breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(14)|lung(30)|ovary(4)|prostate(5)|skin(3)|upper_aerodigestive_tract(4)|urinary_tract(2)	76			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			TTTCGAGTTCCGCGTGGGCGC	0.687000													3	105					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				24	48					0	0	1	0	0
PUM1	9698	broad.mit.edu	37	1	31532162	31532162	+	Missense_Mutation	SNP	G	G	C			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr1:31532162G>C	ENST00000373747.3	-	2	351	c.252C>G	c.(250-252)ttC>ttG	p.F84L	PUM1_ENST00000426105.2_Missense_Mutation_p.F84L|PUM1_ENST00000440538.2_Missense_Mutation_p.F84L|PUM1_ENST00000373742.2_Missense_Mutation_p.F120L|PUM1_ENST00000424085.2_Missense_Mutation_p.F84L|PUM1_ENST00000257075.5_Missense_Mutation_p.F84L|PUM1_ENST00000423018.2_Missense_Mutation_p.F84L|PUM1_ENST00000373741.4_Missense_Mutation_p.F120L	NM_001020658.1	NP_001018494.1	Q14671	PUM1_HUMAN	pumilio RNA-binding family member 1	84					cellular membrane organization|post-Golgi vesicle-mediated transport|regulation of translation	cytosol	RNA binding			breast(1)|central_nervous_system(2)|endometrium(8)|kidney(4)|large_intestine(8)|lung(17)|ovary(2)|pancreas(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	48		Colorectal(325;0.0211)|Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0308)|all_neural(195;0.0381)|Breast(348;0.0848)|Medulloblastoma(700;0.123)		STAD - Stomach adenocarcinoma(196;0.0232)|READ - Rectum adenocarcinoma(331;0.0681)		GCCTCTGAAAGAAGTAGTCCA	0.542000													4	99					0	0	1	0	0
TUBB8P7	0	broad.mit.edu	37	16	90162513	90162513	+	RNA	SNP	T	T	C			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr16:90162513T>C	ENST00000564451.1	+	0	1866				TUBB8P7_ENST00000567960.1_RNA														p.N415N(2)									GCAACATGAATGACCTGGTGT	0.537000													6	168					0	0	1	0	0
USH2A	7399	broad.mit.edu	37	1	216390846	216390846	+	Missense_Mutation	SNP	A	A	G			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr1:216390846A>G	ENST00000366943.2	-	15	3426	c.3040T>C	c.(3040-3042)Tgt>Cgt	p.C1014R	USH2A_ENST00000307340.3_Missense_Mutation_p.C1014R|USH2A_ENST00000366942.3_Missense_Mutation_p.C1014R			O75445	USH2A_HUMAN	Usher syndrome 2A (autosomal recessive, mild)	1014	Laminin EGF-like 10.				maintenance of organ identity|photoreceptor cell maintenance|response to stimulus|sensory perception of sound	basement membrane|cytoplasm|integral to membrane|stereocilium membrane	collagen binding			NS(7)|breast(20)|central_nervous_system(3)|cervix(2)|endometrium(32)|haematopoietic_and_lymphoid_tissue(4)|kidney(13)|large_intestine(71)|liver(2)|lung(282)|ovary(25)|pancreas(2)|prostate(12)|skin(22)|stomach(7)|upper_aerodigestive_tract(20)|urinary_tract(3)	527				OV - Ovarian serous cystadenocarcinoma(81;0.0547)|all cancers(67;0.0875)		ACCAAGTGACAGGTTTCATTC	0.403000										HNSCC(13;0.011)			16	37					0	0	1	0	0
DYNC1H1	1778	broad.mit.edu	37	14	102466737	102466737	+	Splice_Site	SNP	G	G	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr14:102466737G>T	ENST00000360184.4	+	18	4238		c.e18+1			NM_001376.4	NP_001367.2	Q14204	DYHC1_HUMAN	dynein, cytoplasmic 1, heavy chain 1						cytoplasmic mRNA processing body assembly|G2/M transition of mitotic cell cycle|microtubule-based movement|mitotic spindle organization|stress granule assembly|transport	centrosome|cytoplasmic dynein complex|cytosol|Golgi apparatus|microtubule	ATP binding|ATPase activity, coupled|microtubule motor activity|protein binding	p.?(1)		NS(1)|biliary_tract(1)|breast(4)|central_nervous_system(5)|cervix(1)|endometrium(21)|haematopoietic_and_lymphoid_tissue(3)|kidney(10)|large_intestine(28)|lung(60)|ovary(9)|pancreas(1)|prostate(6)|skin(7)|stomach(3)|upper_aerodigestive_tract(4)|urinary_tract(2)	166						GCCTCGAAAGGTATATCATGA	0.403000													12	27					2.27111e-07	2.67189e-07	1	1	0
ADARB1	104	broad.mit.edu	37	21	46624644	46624644	+	Missense_Mutation	SNP	G	G	C			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr21:46624644G>C	ENST00000539173.1	+	10	2295	c.1860G>C	c.(1858-1860)ttG>ttC	p.L620F	ADARB1_ENST00000389863.4_Missense_Mutation_p.L620F|ADARB1_ENST00000348831.4_Missense_Mutation_p.L580F|ADARB1_ENST00000437626.1_3'UTR|ADARB1_ENST00000360697.3_Missense_Mutation_p.L620F	NM_015833.3	NP_056648.1	P78563	RED1_HUMAN	adenosine deaminase, RNA-specific, B1	620	A to I editase.				adenosine to inosine editing|mRNA modification|mRNA processing|RNA processing	nucleoplasm|nucleus	double-stranded RNA adenosine deaminase activity|double-stranded RNA binding|metal ion binding|mRNA binding|RNA binding			endometrium(4)|kidney(1)|large_intestine(3)|lung(8)|skin(1)	17				Colorectal(79;0.115)		ACAAGCCTTTGCTCAGTGGCA	0.488000													25	35					0	0	1	0	0
SYT1	6857	broad.mit.edu	37	12	79747297	79747297	+	Missense_Mutation	SNP	G	G	A			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr12:79747297G>A	ENST00000261205.4	+	9	1483	c.826G>A	c.(826-828)Gat>Aat	p.D276N	SYT1_ENST00000552744.1_Missense_Mutation_p.D276N|SYT1_ENST00000457153.2_Missense_Mutation_p.D273N|SYT1_ENST00000393240.3_Missense_Mutation_p.D276N	NM_005639.2	NP_005630.1	P21579	SYT1_HUMAN	synaptotagmin I	276	Phospholipid binding (Probable).				detection of calcium ion|glutamate secretion|neurotransmitter secretion|protein homooligomerization	cell junction|chromaffin granule membrane|clathrin sculpted acetylcholine transport vesicle membrane|clathrin sculpted gamma-aminobutyric acid transport vesicle membrane|clathrin sculpted glutamate transport vesicle membrane|clathrin sculpted monoamine transport vesicle membrane|endocytic vesicle membrane|integral to membrane|synaptic vesicle membrane	1-phosphatidylinositol binding|low-density lipoprotein particle receptor binding|metal ion binding|syntaxin-1 binding|transporter activity			NS(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(11)|ovary(1)|pancreas(2)|skin(6)	25						GAAATTGGGTGATATCTGCTT	0.363000													5	149					0	0	1	0	0
MTOR	2475	broad.mit.edu	37	1	11297986	11297986	+	Silent	SNP	G	G	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr1:11297986G>T	ENST00000361445.4	-	13	2198	c.2122C>A	c.(2122-2124)Cgg>Agg	p.R708R		NM_004958.3	NP_004949.1	P42345	MTOR_HUMAN	mechanistic target of rapamycin (serine/threonine kinase)	708					cell growth|cellular response to hypoxia|insulin receptor signaling pathway|nerve growth factor receptor signaling pathway|peptidyl-serine phosphorylation|phosphatidylinositol-mediated signaling|protein autophosphorylation|protein catabolic process|response to amino acid stimulus|response to nutrient|T cell costimulation|TOR signaling cascade	endoplasmic reticulum membrane|Golgi membrane|lysosome|mitochondrial outer membrane|phosphatidylinositol 3-kinase complex|PML body|TORC1 complex|TORC2 complex	ATP binding|phosphoprotein binding|protein serine/threonine kinase activity			breast(5)|central_nervous_system(7)|endometrium(20)|kidney(34)|large_intestine(21)|lung(43)|ovary(9)|prostate(3)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	149						GCCAGCTCCCGGATCTCAAAC	0.572000													3	80					1	1	1	1	0
NXN	64359	broad.mit.edu	37	17	726925	726925	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr17:726925C>T	ENST00000336868.3	-	3	650	c.559G>A	c.(559-561)Gag>Aag	p.E187K	NXN_ENST00000537628.2_5'UTR|NXN_ENST00000577098.1_5'UTR|NXN_ENST00000575801.1_Missense_Mutation_p.E79K	NM_022463.4	NP_071908.2	Q6DKJ4	NXN_HUMAN	nucleoredoxin	187	Thioredoxin.				cell differentiation|cell redox homeostasis|multicellular organismal development|Wnt receptor signaling pathway	cytosol|nucleus	protein-disulfide reductase activity			breast(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(2)|ovary(2)|pancreas(1)|prostate(1)	13				UCEC - Uterine corpus endometrioid carcinoma (25;0.0237)		CTGCTGCTCTCCAGAGACTGC	0.552000													3	55					0	0	1	0	0
CYP4Z2P	0	broad.mit.edu	37	1	47310359	47310360	+	RNA	INS	-	-	T			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr1:47310359_47310360insT	ENST00000505841.1	-	0	1269					NR_002788.2																						CAAAAACAAAACCCTAGATATT	0.421													3	6	---	---	---	---					
POP5	51367	broad.mit.edu	37	12	121017154	121017156	+	In_Frame_Del	DEL	CTC	CTC	-			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr12:121017154_121017156delCTC	ENST00000341039.2	-	4	323_325	c.307_309delGAG	c.(307-309)del	p.E103del	POP5_ENST00000542776.1_5'UTR|POP5_ENST00000357500.4_In_Frame_Del_p.E153del	NM_198202.1	NP_937845.1	Q969H6	POP5_HUMAN	processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)	153					tRNA processing		protein binding|ribonuclease P activity			breast(1)|endometrium(1)|large_intestine(2)|lung(2)|ovary(1)	7	all_neural(191;0.077)|Medulloblastoma(191;0.0922)					CCTCACCTGACTCCTCCTCCTCC	0.517													7	204	---	---	---	---					
AFG3L1P	0	broad.mit.edu	37	16	90053806	90053806	+	RNA	DEL	G	G	-			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr16:90053806delG	ENST00000437774.1	+	0	731					NR_003226.1																						aggtggaggaggtggaggagg	0.642													2	4	---	---	---	---					
DDX27	55661	broad.mit.edu	37	20	47858504	47858504	+	Frame_Shift_Del	DEL	A	A	-			TCGA-EL-A3T6-01A-11D-A21Z-08	TCGA-EL-A3T6-11A-11D-A21Z-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5140ce7c-fceb-49d3-9c00-5dcb081ca0c0	021c6d1e-4b0c-4270-9bb5-9f1ce9d24fd3	g.chr20:47858504delA	ENST00000371764.4	+	17	2074	c.2065delA	c.(2065-2067)aafs	p.K691fs	ZNFX1_ENST00000371754.4_Intron|DDX27_ENST00000484427.1_3'UTR|ZNFX1_ENST00000469991.1_Intron	NM_017895.7	NP_060365.7	Q96GQ7	DDX27_HUMAN	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	691						nucleus	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding	p.K691fs*4(3)		NS(1)|breast(1)|endometrium(2)|kidney(3)|large_intestine(12)|lung(19)|ovary(1)|prostate(2)|skin(3)|urinary_tract(1)	45			BRCA - Breast invasive adenocarcinoma(12;0.000899)|COAD - Colon adenocarcinoma(4;0.14)|Colorectal(8;0.166)			GAAGGATGCCAAAAAAAAGGG	0.488													7	62	---	---	---	---					
