Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MLIP	90523	broad.mit.edu	37	6	53986246	53986246	+	Splice_Site	SNP	T	T	C			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr6:53986246T>C	ENST00000514921.1	+	2	178	c.63_splice	c.e2-1	p.V22_splice	MLIP_ENST00000370877.2_Intron|MLIP_ENST00000509997.1_Intron|MLIP_ENST00000502396.1_Splice_Site_p.V33_splice|MLIP_ENST00000370876.2_Intron|MLIP_ENST00000511744.1_3'UTR|MLIP_ENST00000274897.5_Splice_Site_p.V22_splice|MLIP_ENST00000358276.5_Splice_Site_p.V16_splice			Q5VWP3	MLIP_HUMAN	muscular LMNA-interacting protein	22	Interaction with LMNA.					nuclear envelope|PML body	protein binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(16)|ovary(8)|skin(4)|stomach(1)|urinary_tract(1)	34						GTCTCATAGGTCTCTGCTGGT	0.393000													20	41					0	0	1	0	0
PDE4D	5144	broad.mit.edu	37	5	58511659	58511659	+	Silent	SNP	G	G	A			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr5:58511659G>A	ENST00000340635.6	-	2	766	c.591C>T	c.(589-591)agC>agT	p.S197S	PDE4D_ENST00000503947.1_5'UTR|PDE4D_ENST00000507116.1_Silent_p.S133S|PDE4D_ENST00000503258.1_Silent_p.S67S|PDE4D_ENST00000405755.2_Silent_p.S75S|PDE4D_ENST00000360047.5_Silent_p.S61S|PDE4D_ENST00000502484.2_Silent_p.S136S|PDE4D_ENST00000502575.1_Silent_p.S133S|PDE4D_ENST00000546160.1_Silent_p.S136S	NM_001104631.1	NP_001098101.1	Q08499	PDE4D_HUMAN	phosphodiesterase 4D, cAMP-specific	197					signal transduction	cytosol|insoluble fraction|membrane|microtubule organizing center|soluble fraction	3',5'-cyclic-AMP phosphodiesterase activity|metal ion binding			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(8)|pancreas(1)	15		all_cancers(5;6.5e-58)|all_epithelial(5;1.75e-57)|all_lung(5;6.84e-18)|Lung NSC(5;1.29e-17)|Melanoma(5;0.00168)|Prostate(74;0.00234)|Colorectal(97;0.00629)|Ovarian(174;0.00832)|Breast(144;0.00996)|all_hematologic(6;0.0344)|Hepatocellular(6;0.0742)|Esophageal squamous(6;0.0954)		Epithelial(2;2.6e-55)|all cancers(2;2.66e-49)|OV - Ovarian serous cystadenocarcinoma(10;1.48e-39)|Colorectal(2;8.29e-08)|Lung(2;4.47e-07)|STAD - Stomach adenocarcinoma(2;1.11e-05)|COAD - Colon adenocarcinoma(2;0.00012)|LUSC - Lung squamous cell carcinoma(2;0.000775)|LUAD - Lung adenocarcinoma(3;0.0173)|READ - Rectum adenocarcinoma(2;0.0276)	Adenosine monophosphate(DB00131)|Dyphylline(DB00651)	GGTCATAATCGCTGTCGGATC	0.493000													4	52					0	0	1	0	0
DNAJC11	55735	broad.mit.edu	37	1	6696243	6696243	+	Missense_Mutation	SNP	G	G	C			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr1:6696243G>C	ENST00000377577.5	-	15	1711	c.1588C>G	c.(1588-1590)Cag>Gag	p.Q530E	DNAJC11_ENST00000465508.1_5'UTR|DNAJC11_ENST00000349363.6_Intron|DNAJC11_ENST00000542246.1_Missense_Mutation_p.Q492E|DNAJC11_ENST00000377573.5_Missense_Mutation_p.Q440E|DNAJC11_ENST00000294401.7_Missense_Mutation_p.Q478E	NM_018198.3	NP_060668.2	Q9NVH1	DJC11_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 11	530					protein folding		heat shock protein binding|unfolded protein binding			NS(1)|breast(2)|endometrium(4)|kidney(2)|large_intestine(11)|lung(8)|ovary(2)|skin(1)|urinary_tract(1)	32	Ovarian(185;0.0265)|all_lung(157;0.154)	all_cancers(23;1.97e-27)|all_epithelial(116;1.76e-17)|all_lung(118;2.27e-05)|Lung NSC(185;9.97e-05)|Renal(390;0.00188)|Breast(487;0.00289)|Colorectal(325;0.00342)|Hepatocellular(190;0.0218)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.156)		Colorectal(212;2.34e-07)|COAD - Colon adenocarcinoma(227;2.05e-05)|Kidney(185;7.67e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000639)|KIRC - Kidney renal clear cell carcinoma(229;0.00128)|STAD - Stomach adenocarcinoma(132;0.00179)|READ - Rectum adenocarcinoma(331;0.0649)		CCCCGGAACTGATAGAGCACT	0.542000													17	35					0	0	1	0	0
NRAS	4893	broad.mit.edu	37	1	115256529	115256529	+	Missense_Mutation	SNP	T	T	C	rs11554290		TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr1:115256529T>C	ENST00000369535.4	-	3	435	c.182A>G	c.(181-183)cAa>cGa	p.Q61R		NM_002524.4	NP_002515.1	P01111	RASN_HUMAN	neuroblastoma RAS viral (v-ras) oncogene homolog	61			Q -> K (in neuroblastoma cell).|Q -> R (in lung carcinoma cell and melanoma; dbSNP:rs11554290).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	Golgi membrane|plasma membrane	GTP binding|GTPase activity	p.Q61R(817)|p.Q61L(175)|p.Q61P(23)|p.Q61K(1)		NS(134)|adrenal_gland(9)|autonomic_ganglia(9)|biliary_tract(6)|bone(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(11)|eye(3)|haematopoietic_and_lymphoid_tissue(1115)|kidney(3)|large_intestine(105)|liver(10)|lung(42)|meninges(2)|ovary(7)|pancreas(5)|prostate(8)|skin(1144)|soft_tissue(37)|stomach(5)|testis(8)|thyroid(359)|upper_aerodigestive_tract(28)|urinary_tract(13)	3085	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GTACTCTTCTTGTCCAGCTGT	0.458000	Q61L(C3A_LIVER)|Q61L(HEPG2_LIVER)|Q61L(HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(IPC298_SKIN)|Q61L(KMS21BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MELJUSO_SKIN)|Q61L(MHHES1_BONE)|Q61L(MOLP8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61P(TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(HT1197_URINARY_TRACT)|Q61R(KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(KU1919_URINARY_TRACT)|Q61R(NCIH2347_LUNG)|Q61R(ONS76_CENTRAL_NERVOUS_SYSTEM)|Q61R(SKMEL2_SKIN)|Q61R(SW1271_LUNG)|Q61R(TT2609C02_THYROID)	50	Mis		"""melanoma, MM, AML, thyroid"""				Noonan syndrome	TSP Lung(23;0.16)|Multiple Myeloma(1;<1E-6)			67	103					0	0	1	0	0
USP5	0	broad.mit.edu	37	12	6964920	6964920	+	Splice_Site	SNP	A	A	G			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr12:6964920A>G	ENST00000229268.8	+	3	291	c.237_splice	c.e3-1	p.K80_splice	USP5_ENST00000389231.5_Splice_Site_p.K80_splice	NM_001098536.1	NP_001092006.1	P45974	UBP5_HUMAN	ubiquitin specific peptidase 5 (isopeptidase T)	80					positive regulation of proteasomal ubiquitin-dependent protein catabolic process|protein K48-linked deubiquitination|ubiquitin-dependent protein catabolic process	lysosome	cysteine-type endopeptidase activity|omega peptidase activity|protein binding|ubiquitin thiolesterase activity|zinc ion binding			breast(6)|endometrium(4)|kidney(2)|large_intestine(6)|lung(14)|skin(2)|urinary_tract(2)	36						TCTTTACAGAAAGAGGAGGAC	0.577000													37	48					0	0	1	0	0
SLC22A7	10864	broad.mit.edu	37	6	43266347	43266347	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr6:43266347C>T	ENST00000372585.5	+	1	346	c.251C>T	c.(250-252)gCc>gTc	p.A84V	SLC22A7_ENST00000372574.3_Missense_Mutation_p.A84V|SLC22A7_ENST00000372589.3_Missense_Mutation_p.A84V|SLC22A7_ENST00000487175.1_Intron	NM_153320.2	NP_696961.2	Q9Y694	S22A7_HUMAN	solute carrier family 22 (organic anion transporter), member 7	84						basolateral plasma membrane|integral to plasma membrane|membrane fraction	anion:anion antiporter activity|sodium-independent organic anion transmembrane transporter activity			NS(2)|endometrium(1)|kidney(1)|large_intestine(8)|lung(10)|prostate(1)|skin(3)	26			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.00998)|OV - Ovarian serous cystadenocarcinoma(102;0.0305)			CTCCGCTTTGCCTATCCCCAG	0.652000													3	43					0	0	1	0	0
UBC	7316	broad.mit.edu	37	12	125397369	125397369	+	Missense_Mutation	SNP	T	T	C			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr12:125397369T>C	ENST00000536769.1	-	1	2525	c.949A>G	c.(949-951)Atc>Gtc	p.I317V	UBC_ENST00000538617.1_Intron|UBC_ENST00000546120.1_Missense_Mutation_p.I241V|UBC_ENST00000339647.5_Missense_Mutation_p.I317V			P0CG48	UBC_HUMAN	ubiquitin C	317	Ubiquitin-like 5.				activation of MAPK activity|anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|anti-apoptosis|apoptosis|cellular membrane organization|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA repair|endosome transport|epidermal growth factor receptor signaling pathway|G1/S transition of mitotic cell cycle|I-kappaB kinase/NF-kappaB cascade|induction of apoptosis by extracellular signals|innate immune response|JNK cascade|M/G1 transition of mitotic cell cycle|mRNA metabolic process|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|negative regulation of epidermal growth factor receptor signaling pathway|negative regulation of type I interferon production|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|nerve growth factor receptor signaling pathway|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|S phase of mitotic cell cycle|stress-activated MAPK cascade|T cell receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway|viral reproduction	cytosol|endocytic vesicle membrane|endosome membrane|nucleoplasm|plasma membrane	protein binding			breast(3)|endometrium(4)|kidney(4)|large_intestine(2)|lung(13)|ovary(3)|prostate(4)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;6.17e-05)|Epithelial(86;0.000207)|all cancers(50;0.00308)		TCGAGAGTGATGGTCTTACCA	0.522000													40	116					0	0	1	0	0
DNAH9	1770	broad.mit.edu	37	17	11827171	11827171	+	Missense_Mutation	SNP	C	C	A			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr17:11827171C>A	ENST00000262442.3	+	62	11858	c.11790C>A	c.(11788-11790)caC>caA	p.H3930Q	DNAH9_ENST00000396001.2_Missense_Mutation_p.H242Q|DNAH9_ENST00000454412.2_Missense_Mutation_p.H3930Q	NM_001372.3	NP_001363.2	Q9NYC9	DYH9_HUMAN	dynein, axonemal, heavy chain 9	3930	AAA 6 (By similarity).				cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4)	290		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		AGAACTTTCACAACGTGTCTT	0.453000													6	61					0.0215528	0.0215528	1	1	0
TBC1D2B	23102	broad.mit.edu	37	15	78305349	78305349	+	Silent	SNP	G	G	A			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr15:78305349G>A	ENST00000409931.3	-	9	2157	c.2086C>T	c.(2086-2088)Ctg>Ttg	p.L696L	TBC1D2B_ENST00000300584.3_Silent_p.L696L			Q9UPU7	TBD2B_HUMAN	TBC1 domain family, member 2B	696	Rab-GAP TBC.					intracellular	protein binding|Rab GTPase activator activity			breast(3)|cervix(2)|endometrium(4)|kidney(1)|large_intestine(7)|lung(2)|ovary(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)	26						GCCTTCTGCAGCAAGGTCTGG	0.562000													3	20					0	0	1	0	0
TRPC3	7222	broad.mit.edu	37	4	122853799	122853799	+	Missense_Mutation	SNP	C	C	T			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr4:122853799C>T	ENST00000264811.5	-	1	813	c.395G>A	c.(394-396)cGt>cAt	p.R132H	TRPC3_ENST00000513531.1_Missense_Mutation_p.R132H|TRPC3_ENST00000379645.3_Missense_Mutation_p.R205H	NM_003305.2	NP_003296.1	Q13507	TRPC3_HUMAN	transient receptor potential cation channel, subfamily C, member 3	120					axon guidance|phototransduction|platelet activation	integral to plasma membrane	protein binding|store-operated calcium channel activity			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(9)|kidney(1)|large_intestine(12)|lung(13)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	51						CAGAGTGAGACGCTTGCTGGC	0.647000													3	40					0	0	1	0	0
NCOA6	23054	broad.mit.edu	37	20	33345744	33345744	+	Silent	SNP	C	C	T			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr20:33345744C>T	ENST00000374796.2	-	8	3377	c.807G>A	c.(805-807)caG>caA	p.Q269Q	NCOA6_ENST00000359003.2_Silent_p.Q269Q			Q14686	NCOA6_HUMAN	nuclear receptor coactivator 6	269	CREBBP-binding region.|Gln-rich.|NCOA1-binding region.|TBP/GTF2A-binding region.				brain development|cellular lipid metabolic process|DNA recombination|DNA repair|DNA replication|estrogen receptor signaling pathway|glucocorticoid receptor signaling pathway|heart development|myeloid cell differentiation|positive regulation of transcription from RNA polymerase II promoter|response to hormone stimulus|transcription initiation from RNA polymerase II promoter	transcription factor complex	chromatin binding|enzyme binding|estrogen receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|retinoid X receptor binding|thyroid hormone receptor binding	p.Q269Q(15)		NS(2)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(9)|kidney(8)|large_intestine(16)|lung(37)|ovary(4)|prostate(5)|skin(13)|upper_aerodigestive_tract(2)|urinary_tract(1)	107						gctgctgctgctgttgttgtt	0.537000													3	41					0	0	1	0	0
CHEK2P2	0	broad.mit.edu	37	15	20490512	20490512	+	RNA	SNP	C	C	A			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr15:20490512C>A	ENST00000555186.1	+	0	492					NR_038836.1																						AGCTCTGGACCTTGTCAAGAA	0.438000													19	72					1.9806e-07	2.14565e-07	1	1	0
RP11-423O2.5	0	broad.mit.edu	37	1	142803276	142803278	+	RNA	DEL	AAC	AAC	-			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr1:142803276_142803278delAAC	ENST00000423385.1	-	0	1687_1689																											ACCAAACCAAaacaacaacaaca	0.345													3	5	---	---	---	---					
HLA-DRB6	0	broad.mit.edu	37	6	32521545	32521546	+	RNA	INS	-	-	AAGG	rs144810212	by1000genomes	TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr6:32521545_32521546insAAGG	ENST00000411500.1	-	0	851					NR_001298.1																						TTGGGGAAAGACTTTATCCAGG	0.436													3	5	---	---	---	---					
ZNF703	80139	broad.mit.edu	37	8	37555481	37555481	+	Frame_Shift_Del	DEL	G	G	-			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr8:37555481delG	ENST00000331569.4	+	2	1291	c.1062delG	c.(1060-1062)ccfs	p.P354fs		NM_025069.1	NP_079345.1	Q9H7S9	ZN703_HUMAN	zinc finger protein 703	354	Gly-rich.				adherens junction assembly|mammary gland epithelial cell differentiation|negative regulation of homotypic cell-cell adhesion|negative regulation of transcription, DNA-dependent|positive regulation of cell migration|positive regulation of epithelial to mesenchymal transition|positive regulation of mammary gland epithelial cell proliferation|regulation of canonical Wnt receptor signaling pathway|regulation of cell cycle|regulation of transforming growth factor beta receptor signaling pathway|transcription, DNA-dependent	cytoplasm|nucleus	nucleic acid binding|protein binding|zinc ion binding		FGFR1/ZNF703(2)	breast(1)|cervix(1)|kidney(1)|large_intestine(2)|lung(1)|pancreas(1)	7			BRCA - Breast invasive adenocarcinoma(5;7.93e-25)|LUSC - Lung squamous cell carcinoma(8;1.05e-09)			GCCTGCCGCCGGGCAAGCCCC	0.711													2	4	---	---	---	---					
UBR5	51366	broad.mit.edu	37	8	103271235	103271235	+	Frame_Shift_Del	DEL	A	A	-			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr8:103271235delA	ENST00000520539.1	-	57	8685	c.8079delT	c.(8077-8079)ttfs	p.F2693fs	UBR5_ENST00000518205.1_Frame_Shift_Del_p.F421fs|UBR5_ENST00000220959.4_Frame_Shift_Del_p.F2692fs|UBR5_ENST00000521922.1_Frame_Shift_Del_p.F2686fs	NM_015902.5	NP_056986.2	O95071	UBR5_HUMAN	ubiquitin protein ligase E3 component n-recognin 5	2693	HECT.				cell proliferation|positive regulation of canonical Wnt receptor signaling pathway|positive regulation of catenin import into nucleus|positive regulation of protein import into nucleus, translocation|progesterone receptor signaling pathway|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process|response to DNA damage stimulus	nucleus|soluble fraction	protein binding|RNA binding|ubiquitin-ubiquitin ligase activity|zinc ion binding			NS(1)|breast(13)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(8)|large_intestine(19)|liver(1)|lung(51)|ovary(6)|pancreas(1)|prostate(5)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(2)	124	all_cancers(14;8e-07)|all_epithelial(15;2.18e-08)|Lung NSC(17;2.55e-05)|all_lung(17;8.85e-05)		OV - Ovarian serous cystadenocarcinoma(57;0.000442)			TGAAAGAGGTAAAACTGATCA	0.333													10	26	---	---	---	---					
IRF2BPL	64207	broad.mit.edu	37	14	77493648	77493650	+	In_Frame_Del	DEL	GCG	GCG	-			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr14:77493648_77493650delGCG	ENST00000238647.3	-	1	1384_1386	c.486_488delCGC	c.(484-489)gct>gc	p.AA162del		NM_024496.3	NP_078772.1	Q9H1B7	I2BPL_HUMAN	interferon regulatory factor 2 binding protein-like	162	Poly-Ala.					nucleus				endometrium(2)|kidney(1)|lung(3)|ovary(1)|prostate(1)|skin(1)|urinary_tract(2)	11						TTCCACCgcagcggcggcggcgg	0.749													5	8	---	---	---	---					
SLC8A2	6543	broad.mit.edu	37	19	47935681	47935683	+	In_Frame_Del	DEL	TCC	TCC	-			TCGA-EL-A4K2-01A-11D-A257-08	TCGA-EL-A4K2-11A-11D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ba57094e-ee91-4235-9cfb-88659af9a99e	406c2a3b-2a90-403c-b247-e484b0b313e3	g.chr19:47935681_47935683delTCC	ENST00000236877.6	-	9	2525_2527	c.2130_2132delGGA	c.(2128-2133)gac>ga	p.ED710del	SLC8A2_ENST00000542837.1_In_Frame_Del_p.ED466del|SLC8A2_ENST00000539381.1_In_Frame_Del_p.ED173del|SLC8A2_ENST00000601757.1_5'UTR	NM_015063.2	NP_055878.1	Q9UPR5	NAC2_HUMAN	solute carrier family 8 (sodium/calcium exchanger), member 2	710					cell communication|platelet activation	integral to membrane|plasma membrane	calcium:sodium antiporter activity|calmodulin binding			breast(1)|endometrium(4)|kidney(2)|large_intestine(4)|lung(10)|ovary(2)|prostate(2)|skin(5)|stomach(1)	31		all_cancers(25;3.05e-07)|all_lung(116;4.19e-06)|Lung NSC(112;7.16e-06)|all_epithelial(76;7.65e-06)|all_neural(266;0.0652)|Ovarian(192;0.086)|Breast(70;0.173)		OV - Ovarian serous cystadenocarcinoma(262;0.000501)|all cancers(93;0.00058)|Epithelial(262;0.0181)|GBM - Glioblastoma multiforme(486;0.0457)		CCGGGACCCGTCCTCCTCCTCCT	0.616													7	99	---	---	---	---					
