Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MT-CYB	4519	broad.mit.edu	37	MT	14924	14924	+	Missense_Mutation	SNP	T	T	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chrM:14924T>C	ENST00000361789.2	+	1	178	c.178T>C	c.(178-180)Tca>Cca	p.60_60insP						mitochondrially encoded cytochrome b											breast(6)|endometrium(25)|kidney(33)|prostate(1)	65						CACCAGACGCCTCAACCGCCT	0.498000													4	53					0	0	1	0	0
COL27A1	85301	broad.mit.edu	37	9	116931244	116931244	+	Missense_Mutation	SNP	A	A	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr9:116931244A>C	ENST00000356083.3	+	3	1800	c.1409A>C	c.(1408-1410)aAg>aCg	p.K470T		NM_032888.2	NP_116277.2	Q8IZC6	CORA1_HUMAN	collagen, type XXVII, alpha 1	470	Pro-rich.				cell adhesion		extracellular matrix structural constituent			central_nervous_system(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(3)|kidney(4)|large_intestine(17)|lung(30)|ovary(4)|prostate(6)|skin(3)|soft_tissue(1)|stomach(1)|urinary_tract(3)	80						CATGCCAGTAAGCCGGCCTCT	0.592000													102	150					0	0	1	0	0
ZNF835	90485	broad.mit.edu	37	19	57176120	57176120	+	Silent	SNP	C	C	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr19:57176120C>T	ENST00000537055.2	-	2	678	c.447G>A	c.(445-447)caG>caA	p.Q149Q		NM_001005850.2	NP_001005850.2			zinc finger protein 835											endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(10)|lung(22)|pancreas(3)|prostate(3)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)	47						GGTGCACGCTCTGGCTGAAGG	0.637000													7	65					0	0	1	0	0
RP11-262H14.1	0	broad.mit.edu	37	9	66458063	66458063	+	RNA	SNP	G	G	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr9:66458063G>T	ENST00000424345.1	+	0	67																											GCACGGGGGCGGTCAACGGGG	0.657000													3	5					1	1	1	1	0
RP11-119F19.2	0	broad.mit.edu	37	10	81444997	81444997	+	RNA	SNP	T	T	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr10:81444997T>C	ENST00000600376.1	-	0	54				RP11-119F19.2_ENST00000596088.1_RNA																							ACAACAATTTTCGGGCTTGCA	0.612000													3	6					0	0	1	0	0
DZIP3	9666	broad.mit.edu	37	3	108391411	108391411	+	Missense_Mutation	SNP	C	C	A			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr3:108391411C>A	ENST00000361582.3	+	23	2727	c.2497C>A	c.(2497-2499)Cag>Aag	p.Q833K	DZIP3_ENST00000463306.1_Missense_Mutation_p.Q833K	NM_014648.3	NP_055463.1	Q86Y13	DZIP3_HUMAN	DAZ interacting zinc finger protein 3	833					protein polyubiquitination	cytoplasm	polyubiquitin binding|RNA binding|ubiquitin-protein ligase activity|zinc ion binding			breast(3)|central_nervous_system(1)|endometrium(3)|large_intestine(9)|lung(21)|ovary(1)|pancreas(1)|prostate(5)|skin(1)	45						TTTCAGATCTCAGTGGGAAAT	0.363000													4	32					0.00024832	0.000260736	1	1	0
MUC7	4589	broad.mit.edu	37	4	71347138	71347138	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr4:71347138C>T	ENST00000413702.1	+	4	965	c.677C>T	c.(676-678)cCa>cTa	p.P226L	MUC7_ENST00000456088.1_Missense_Mutation_p.P226L|MUC7_ENST00000304887.5_Missense_Mutation_p.P226L	NM_001145006.1	NP_001138478.1	Q8TAX7	MUC7_HUMAN	mucin 7, secreted	226	Thr-rich.					extracellular region	protein binding	p.P226L(1)		central_nervous_system(1)|endometrium(3)|kidney(5)|large_intestine(2)|lung(23)|ovary(3)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	42			Lung(101;0.211)			CCAGCTCCACCATCTTCCTCA	0.582000													5	236					0	0	1	0	0
SLC7A6	9057	broad.mit.edu	37	16	68309107	68309107	+	Missense_Mutation	SNP	G	G	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr16:68309107G>C	ENST00000566454.1	+	4	747	c.478G>C	c.(478-480)Gat>Cat	p.D160H	SLC7A6_ENST00000219343.6_Missense_Mutation_p.D160H	NM_001076785.2	NP_001070253.1	Q92536	YLAT2_HUMAN	solute carrier family 7 (amino acid transporter light chain, y+L system), member 6	160					blood coagulation|cellular amino acid metabolic process|ion transport|leukocyte migration|protein complex assembly	basolateral plasma membrane|integral to plasma membrane	amino acid transmembrane transporter activity|antiporter activity			breast(1)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(4)|prostate(1)|skin(1)	16		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.034)|Epithelial(162;0.0948)		CCCCAGCTGTGATCCCCCATA	0.582000													8	177					0	0	1	0	0
MT-CO2	4513	broad.mit.edu	37	MT	7843	7843	+	Missense_Mutation	SNP	A	A	G			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chrM:7843A>G	ENST00000361739.1	+	1	258	c.258A>G	c.(256-258)atA>atG	p.I86M						mitochondrially encoded cytochrome c oxidase II											endometrium(5)|kidney(8)|lung(2)|pancreas(3)|prostate(1)	19						ATCCTTTACATAACAGACGAG	0.498000													3	84					0	0	1	0	0
TBP	6908	broad.mit.edu	37	6	170871082	170871082	+	Silent	SNP	G	G	A			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr6:170871082G>A	ENST00000392092.2	+	3	537	c.258G>A	c.(256-258)caG>caA	p.Q86Q	TBP_ENST00000540980.1_Silent_p.Q66Q|TBP_ENST00000230354.6_Silent_p.Q86Q	NM_003194.4	NP_003185.1	P20226	TBP_HUMAN	TATA box binding protein	86	Poly-Gln.				cell death|interspecies interaction between organisms|transcription elongation from RNA polymerase II promoter|transcription from RNA polymerase III promoter|viral reproduction	transcription factor TFIIA complex|transcription factor TFIID complex	repressing transcription factor binding|transcription regulatory region DNA binding	p.Q86Q(2)		breast(2)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(2)|lung(9)|ovary(1)|prostate(4)|urinary_tract(1)	26		Breast(66;5.08e-05)|Ovarian(120;0.125)|Esophageal squamous(34;0.246)		OV - Ovarian serous cystadenocarcinoma(33;1.07e-22)|BRCA - Breast invasive adenocarcinoma(81;5.01e-06)|GBM - Glioblastoma multiforme(31;0.00591)		agcagcagcagcagcagcagc	0.612000													3	21					0	0	1	0	0
CDHR5	53841	broad.mit.edu	37	11	618899	618899	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr11:618899C>T	ENST00000358353.3	-	14	1982	c.1660G>A	c.(1660-1662)Ggt>Agt	p.G554S	CDHR5_ENST00000349570.7_Intron|CDHR5_ENST00000397542.2_Missense_Mutation_p.G554S			Q9HBB8	CDHR5_HUMAN	cadherin-related family member 5	554	4 X 31 AA approximate tandem repeats.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(1)|endometrium(4)|kidney(1)|large_intestine(6)|lung(7)|ovary(1)|skin(2)	23						GTTCCCACACCGGGGGGCATC	0.667000													4	187					0	0	1	0	0
PPP2R3B	28227	broad.mit.edu	37	X	347131	347131	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chrX:347131C>T	ENST00000390665.3	-	1	314	c.296G>A	c.(295-297)gGc>gAc	p.G99D		NM_013239.4	NP_037371.2	Q9Y5P8	P2R3B_HUMAN	protein phosphatase 2, regulatory subunit B'', beta	99					cell cycle arrest|protein dephosphorylation	nucleus|protein phosphatase type 2A complex	calcium ion binding|protein phosphatase type 2A regulator activity|protein serine/threonine phosphatase activity			endometrium(5)|lung(5)|skin(1)	11		all_cancers(21;4.28e-07)|all_epithelial(21;2.07e-08)|all_lung(23;2.81e-05)|Lung NSC(23;0.000693)|Lung SC(21;0.122)				TCTACGGGTGCCTCGAACGTG	0.701000													6	65					0	0	1	0	0
PRDM9	56979	broad.mit.edu	37	5	23527693	23527693	+	Silent	SNP	T	T	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr5:23527693T>C	ENST00000296682.3	+	11	2678	c.2496T>C	c.(2494-2496)taT>taC	p.Y832Y		NM_020227.2	NP_064612.2	Q9NQV7	PRDM9_HUMAN	PR domain containing 9	832					meiosis|regulation of transcription, DNA-dependent|transcription, DNA-dependent	chromosome|nucleoplasm	histone-lysine N-methyltransferase activity|nucleic acid binding|zinc ion binding	p.Y832Y(1)		NS(1)|breast(1)|central_nervous_system(3)|endometrium(15)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(27)|lung(87)|ovary(6)|pancreas(2)|prostate(4)|skin(10)|upper_aerodigestive_tract(11)	172						AGAAGCCCTATGTCTGCAGGG	0.587000										HNSCC(3;0.000094)			4	146					0	0	1	0	0
TMEM132B	114795	broad.mit.edu	37	12	126138656	126138656	+	Silent	SNP	G	G	A			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr12:126138656G>A	ENST00000299308.3	+	9	2645	c.2637G>A	c.(2635-2637)ccG>ccA	p.P879P	TMEM132B_ENST00000535886.1_Silent_p.P391P	NM_052907.2	NP_443139.2	Q14DG7	T132B_HUMAN	transmembrane protein 132B	879						integral to membrane				NS(1)|breast(9)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(2)|large_intestine(11)|liver(1)|lung(45)|ovary(5)|pancreas(1)|prostate(4)|skin(15)|upper_aerodigestive_tract(3)|urinary_tract(1)	107	all_neural(191;0.101)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;0.000423)|Epithelial(86;0.00394)|all cancers(50;0.0362)		GGAAGTCACCGGACCCCAATA	0.517000													25	26					0	0	1	0	0
ZNF208	7757	broad.mit.edu	37	19	22155896	22155896	+	Missense_Mutation	SNP	A	A	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr19:22155896A>C	ENST00000397126.4	-	4	2088	c.1940T>G	c.(1939-1941)aTt>aGt	p.I647S	ZNF208_ENST00000601773.1_Intron|ZNF208_ENST00000599916.1_Intron	NM_007153.3	NP_009084.2			zinc finger protein 208											breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(18)|liver(1)|lung(71)|ovary(6)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	113		all_lung(12;0.0961)|Lung NSC(12;0.103)				TGAGACCTTAATAAAGGTTTT	0.398000													3	41					0	0	1	0	0
PCDH11X	27328	broad.mit.edu	37	X	91133712	91133712	+	Missense_Mutation	SNP	G	G	A			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chrX:91133712G>A	ENST00000373094.1	+	2	3318	c.2473G>A	c.(2473-2475)Gtt>Att	p.V825I	PCDH11X_ENST00000395337.2_Missense_Mutation_p.V825I|PCDH11X_ENST00000504220.1_Missense_Mutation_p.V825I|PCDH11X_ENST00000361724.1_Missense_Mutation_p.V825I|PCDH11X_ENST00000298274.8_Missense_Mutation_p.V825I|PCDH11X_ENST00000373097.1_Missense_Mutation_p.V825I|PCDH11X_ENST00000406881.1_Missense_Mutation_p.V825I|PCDH11X_ENST00000373088.1_Missense_Mutation_p.V825I|PCDH11X_ENST00000361655.2_Missense_Mutation_p.V825I	NM_032968.3	NP_116750.1	Q9BZA7	PC11X_HUMAN	protocadherin 11 X-linked	825					homophilic cell adhesion	integral to plasma membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(30)|liver(4)|lung(92)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	159						CATAACTGTCGTTGTAGTTAT	0.463000													24	42					0	0	1	0	0
WDFY2	115825	broad.mit.edu	37	13	52301855	52301855	+	Missense_Mutation	SNP	C	C	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr13:52301855C>T	ENST00000298125.5	+	6	707	c.527C>T	c.(526-528)tCa>tTa	p.S176L		NM_052950.3	NP_443182.1	Q96P53	WDFY2_HUMAN	WD repeat and FYVE domain containing 2	176							metal ion binding			breast(1)|endometrium(5)|kidney(1)|large_intestine(2)|lung(4)|skin(2)|upper_aerodigestive_tract(1)	16		Breast(56;0.000208)|Lung NSC(96;0.000517)|Prostate(109;0.0041)|Hepatocellular(98;0.0652)|Myeloproliferative disorder(33;0.164)|all_neural(104;0.191)		GBM - Glioblastoma multiforme(99;9e-08)		GGTGACCACTCAGGCCAAGTA	0.403000													10	74					0	0	1	0	0
PROX1-AS1	0	broad.mit.edu	37	1	214090692	214090694	+	RNA	DEL	TCC	TCC	-			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr1:214090692_214090694delTCC	ENST00000433082.2	-	0	195				PROX1-AS1_ENST00000600591.1_RNA|PROX1-AS1_ENST00000601854.1_RNA|PROX1-AS1_ENST00000601744.1_RNA|PROX1-AS1_ENST00000413560.1_RNA|PROX1-AS1_ENST00000601907.1_RNA|PROX1-AS1_ENST00000593620.1_RNA|PROX1-AS1_ENST00000601335.1_RNA|PROX1-AS1_ENST00000598105.1_RNA																							ctccttctgttcctcctcctcct	0.488													3	6	---	---	---	---					
RP1-230L10.1	0	broad.mit.edu	37	6	164134479	164134480	+	RNA	INS	-	-	C			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr6:164134479_164134480insC	ENST00000452944.1	+	0	102																											tctcctccccaccccaccctct	0.644													4	9	---	---	---	---					
PRSS51	0	broad.mit.edu	37	8	10373507	10373508	+	RNA	INS	-	-	T			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr8:10373507_10373508insT	ENST00000523024.1	-	0	156				PRSS51_ENST00000521149.1_RNA																							AGTGTTGTTGAttttttgtttt	0.505													2	4	---	---	---	---					
AKT1	207	broad.mit.edu	37	14	105242073	105242075	+	In_Frame_Del	DEL	CTC	CTC	-			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr14:105242073_105242075delCTC	ENST00000554581.1	-	4	1829_1831	c.349_351delGAG	c.(349-351)del	p.E117del	AKT1_ENST00000554848.1_In_Frame_Del_p.E117del|AKT1_ENST00000544168.1_In_Frame_Del_p.E55del|AKT1_ENST00000402615.2_In_Frame_Del_p.E117del|AKT1_ENST00000349310.3_In_Frame_Del_p.E117del|AKT1_ENST00000555528.1_In_Frame_Del_p.E117del|AKT1_ENST00000407796.2_In_Frame_Del_p.E117del			P31749	AKT1_HUMAN	v-akt murine thymoma viral oncogene homolog 1	117					activation of pro-apoptotic gene products|activation-induced cell death of T cells|endocrine pancreas development|G-protein coupled receptor protein signaling pathway|glucose metabolic process|glycogen biosynthetic process|induction of apoptosis by intracellular signals|insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|mRNA metabolic process|negative regulation of fatty acid beta-oxidation|negative regulation of plasma membrane long-chain fatty acid transport|negative regulation of protein kinase activity|nerve growth factor receptor signaling pathway|nitric oxide biosynthetic process|peptidyl-serine phosphorylation|phosphatidylinositol-mediated signaling|platelet activation|positive regulation of blood vessel endothelial cell migration|positive regulation of cell growth|positive regulation of cyclin-dependent protein kinase activity involved in G1/S|positive regulation of establishment of protein localization in plasma membrane|positive regulation of fat cell differentiation|positive regulation of glucose import|positive regulation of glycogen biosynthetic process|positive regulation of lipid biosynthetic process|positive regulation of nitric oxide biosynthetic process|positive regulation of nitric-oxide synthase activity|positive regulation of peptidyl-serine phosphorylation|positive regulation of sequence-specific DNA binding transcription factor activity|protein autophosphorylation|protein import into nucleus, translocation|regulation of neuron projection development|regulation of translation|response to fluid shear stress|response to heat|response to UV-A|T cell costimulation	cytosol|nucleoplasm|plasma membrane	enzyme binding|identical protein binding|nitric-oxide synthase regulator activity|phosphatidylinositol-3,4,5-trisphosphate binding|phosphatidylinositol-3,4-bisphosphate binding|protein serine/threonine kinase activity			NS(3)|breast(97)|central_nervous_system(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(4)|kidney(1)|large_intestine(7)|lung(10)|ovary(2)|pancreas(1)|prostate(6)|skin(5)|thyroid(10)|urinary_tract(15)	176		all_cancers(154;3.77e-06)|all_lung(585;3.24e-07)|all_epithelial(191;3.45e-05)|all_neural(303;0.0459)|Melanoma(154;0.155)	all cancers(16;0.000486)|OV - Ovarian serous cystadenocarcinoma(23;0.00647)|Epithelial(46;0.0153)|GBM - Glioblastoma multiforme(11;0.116)	all cancers(159;0.0107)|OV - Ovarian serous cystadenocarcinoma(161;0.0132)|Epithelial(152;0.243)	Adenosine triphosphate(DB00171)|Arsenic trioxide(DB01169)	GGAAGTCCATCTCCTCCTCCTCC	0.631		1	Mis		"""breast, colorectal, ovarian, NSCLC"""								8	152	---	---	---	---					
RP11-314A20.2	0	broad.mit.edu	37	17	4608074	4608075	+	RNA	DEL	GT	GT	-			TCGA-EM-A3FQ-06A-11D-A21A-08	TCGA-EM-A3FQ-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	31ea2466-3e87-4ec2-a15c-0722473852e7	2125f0b1-c6b9-4b65-a6db-9fd4422e7c7e	g.chr17:4608074_4608075delGT	ENST00000497885.1	+	0	141					NR_103482.1																						AATCAGTAACGTGTGTGTGTGT	0.515													3	6	---	---	---	---					
