Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SMCHD1	23347	broad.mit.edu	37	18	2728543	2728543	+	Silent	SNP	A	A	G			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr18:2728543A>G	ENST00000320876.6	+	23	3200	c.2862A>G	c.(2860-2862)ttA>ttG	p.L954L	RP11-703M24.5_ENST00000583546.1_RNA|SMCHD1_ENST00000261598.8_Silent_p.L954L	NM_015295.2	NP_056110.2	A6NHR9	SMHD1_HUMAN	structural maintenance of chromosomes flexible hinge domain containing 1	954					chromosome organization		ATP binding			NS(3)|breast(3)|cervix(1)|endometrium(3)|kidney(3)|large_intestine(16)|lung(15)|pancreas(1)	45						TGGAAGTTTTAGATGAATCAG	0.358000													21	27					0	0	1	0	0
ZFYVE20	64145	broad.mit.edu	37	3	15124046	15124046	+	Missense_Mutation	SNP	A	A	T			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr3:15124046A>T	ENST00000253699.3	-	9	1281	c.668T>A	c.(667-669)gTc>gAc	p.V223D	ZFYVE20_ENST00000476527.2_Missense_Mutation_p.V223D|ZFYVE20_ENST00000435849.3_Intron|ZFYVE20_ENST00000449964.2_Intron	NM_022340.2	NP_071735.2	Q9H1K0	RBNS5_HUMAN	zinc finger, FYVE domain containing 20	223	Necessary for the correct targeting to endosomes.|Ser-rich.				blood coagulation|endosome transport|protein transport	early endosome membrane|plasma membrane	protein binding|zinc ion binding			NS(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(10)|skin(3)|stomach(1)|urinary_tract(2)	26						GGAGCCATGGACACTGTTGGG	0.592000													5	57					0	0	1	0	0
PDSS1	23590	broad.mit.edu	37	10	27035361	27035361	+	Missense_Mutation	SNP	C	C	A			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr10:27035361C>A	ENST00000376215.5	+	12	1260	c.1207C>A	c.(1207-1209)Ctc>Atc	p.L403I	PDSS1_ENST00000470978.1_3'UTR|PDSS1_ENST00000376203.5_3'UTR	NM_014317.3	NP_055132.2	Q5T2R2	DPS1_HUMAN	prenyl (decaprenyl) diphosphate synthase, subunit 1	403					isoprenoid biosynthetic process|ubiquinone biosynthetic process	mitochondrion	metal ion binding|protein heterodimerization activity			autonomic_ganglia(1)|endometrium(1)|kidney(7)|large_intestine(6)|lung(5)|prostate(1)	21						AAGAGATGCCCTCATTCAGCT	0.433000													20	40					7.45023e-12	8.1076e-12	1	1	0
RP11-419C5.2	0	broad.mit.edu	37	16	70016573	70016573	+	Missense_Mutation	SNP	G	G	A	rs3748384	by1000genomes	TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr16:70016573G>A	ENST00000325845.7	-	22	2361	c.292C>T	c.(292-294)Cgt>Tgt	p.R98C	RP11-419C5.2_ENST00000532298.1_Missense_Mutation_p.R113C|PDXDC2P_ENST00000531894.1_RNA|RP11-419C5.2_ENST00000525562.1_5'UTR																breast(2)|endometrium(2)|kidney(6)|lung(2)|prostate(1)	13						TCCTGTCTACGGCGGTTGGAC	0.483000													5	39					0	0	1	0	0
OSCP1	127700	broad.mit.edu	37	1	36898067	36898067	+	Missense_Mutation	SNP	T	T	C	rs34409118	byFrequency	TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr1:36898067T>C	ENST00000356637.5	-	4	484	c.421A>G	c.(421-423)Acc>Gcc	p.T141A	OSCP1_ENST00000315643.9_Missense_Mutation_p.T141A|OSCP1_ENST00000433045.2_Missense_Mutation_p.T86A|OSCP1_ENST00000235532.5_Missense_Mutation_p.T131A|OSCP1_ENST00000354267.3_Missense_Mutation_p.T131A			Q8WVF1	OSCP1_HUMAN	organic solute carrier partner 1	141			T -> A (in dbSNP:rs34409118).		transport	basal plasma membrane		p.T141A(2)		NS(1)|breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(5)|ovary(3)|pancreas(1)|prostate(1)|skin(1)|stomach(2)|urinary_tract(1)	22						TGCAGGATGGTTGGGGAGTCT	0.502000													6	88					0	0	1	0	0
PAQR4	124222	broad.mit.edu	37	16	3019765	3019765	+	Silent	SNP	G	G	A			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr16:3019765G>A	ENST00000318782.8	+	1	520	c.90G>A	c.(88-90)cgG>cgA	p.R30R	PKMYT1_ENST00000431515.2_Intron|PAQR4_ENST00000293978.8_Silent_p.R30R|PAQR4_ENST00000572687.1_Silent_p.R30R|PKMYT1_ENST00000571102.1_Intron|PAQR4_ENST00000576565.1_Intron	NM_152341.3	NP_689554.2	Q8N4S7	PAQR4_HUMAN	progestin and adipoQ receptor family member IV	30						integral to membrane	receptor activity			kidney(1)|large_intestine(1)|lung(3)|ovary(1)|prostate(1)|urinary_tract(1)	8						CCGGGTACCGGCCCGCCAGCA	0.692000													10	22					0	0	1	0	0
KYNU	8942	broad.mit.edu	37	2	143790821	143790821	+	Silent	SNP	T	T	G			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr2:143790821T>G	ENST00000264170.4	+	12	1230	c.972T>G	c.(970-972)ccT>ccG	p.P324P	KYNU_ENST00000409512.1_Silent_p.P324P	NM_003937.2	NP_003928.1	Q16719	KYNU_HUMAN	kynureninase	324					anthranilate metabolic process|NAD biosynthetic process|quinolinate biosynthetic process|response to interferon-gamma|response to vitamin B6	cytosol|mitochondrion|soluble fraction	kynureninase activity|protein homodimerization activity			large_intestine(10)|liver(1)|lung(18)|prostate(3)|skin(4)	36				BRCA - Breast invasive adenocarcinoma(221;0.072)	L-Alanine(DB00160)|Pyridoxal Phosphate(DB00114)	AGTTAATCCCTGGGGTCTGTG	0.378000													54	97					0	0	1	0	0
PCK2	5106	broad.mit.edu	37	14	24569430	24569430	+	Silent	SNP	C	C	T			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr14:24569430C>T	ENST00000396973.4	+	7	1489	c.1242C>T	c.(1240-1242)tgC>tgT	p.C414C	PCK2_ENST00000216780.4_Intron|PCK2_ENST00000545054.2_Intron|PCK2_ENST00000559250.1_Intron|PCK2_ENST00000561286.1_Intron|PCK2_ENST00000558096.1_Intron|NRL_ENST00000561028.1_Intron	NM_001018073.1	NP_001018083.1	Q16822	PCKGM_HUMAN	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0					gluconeogenesis	mitochondrial matrix	GTP binding|metal ion binding|phosphoenolpyruvate carboxykinase (GTP) activity			breast(2)|endometrium(2)|kidney(3)|large_intestine(3)|lung(5)|ovary(1)|prostate(1)|skin(1)	18				GBM - Glioblastoma multiforme(265;0.0184)		CTGGTATGTGCGGTGGGGAAG	0.577000													5	44					0	0	1	0	0
KRT80	144501	broad.mit.edu	37	12	52567461	52567461	+	Missense_Mutation	SNP	C	C	T			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr12:52567461C>T	ENST00000313234.5	-	5	851	c.754G>A	c.(754-756)Gtg>Atg	p.V252M	KRT80_ENST00000394815.2_Missense_Mutation_p.V252M	NM_001081492.1	NP_001074961.1	Q6KB66	K2C80_HUMAN	keratin 80	252	Coil 2.|Rod.					keratin filament	structural molecule activity			endometrium(2)|large_intestine(2)|lung(1)	5				BRCA - Breast invasive adenocarcinoma(357;0.108)		ACCTCCTCCACGATGCCGCTC	0.662000													5	73					0	0	1	0	0
ZNF814	730051	broad.mit.edu	37	19	58385546	58385546	+	Missense_Mutation	SNP	G	G	T			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr19:58385546G>T	ENST00000435989.2	-	3	1446	c.1212C>A	c.(1210-1212)gaC>gaA	p.D404E	ZNF814_ENST00000595295.1_Intron|ZNF814_ENST00000597342.1_Intron|ZNF814_ENST00000600634.1_Intron|ZNF814_ENST00000597832.1_Intron|ZNF814_ENST00000596604.1_Intron	NM_001144989.1	NP_001138461.1	B7Z6K7	ZN814_HUMAN	zinc finger protein 814	404					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding	p.D404E(10)		NS(1)|central_nervous_system(2)|endometrium(3)|kidney(9)|lung(2)|prostate(4)|skin(1)|urinary_tract(3)	25						AATGTTTTTTGTCAGTGTGAA	0.393000													4	8					0.00909568	0.00934834	1	1	0
MT-ND5	4540	broad.mit.edu	37	MT	12439	12439	+	Missense_Mutation	SNP	T	T	C			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chrM:12439T>C	ENST00000361567.2	+	1	103	c.103T>C	c.(103-105)Tat>Cat	p.Y35H				P03915	NU5M_HUMAN	mitochondrially encoded NADH dehydrogenase 5	35					mitochondrial electron transport, NADH to ubiquinone|transport	integral to membrane|mitochondrial respiratory chain complex I	NADH dehydrogenase (ubiquinone) activity			breast(4)|endometrium(29)|kidney(33)|pancreas(1)|prostate(7)	74					NADH(DB00157)	CATACCCCCATTATGTAAAAT	0.418000													3	6					0	0	1	0	0
RGPD8	727851	broad.mit.edu	37	2	113127775	113127775	+	Missense_Mutation	SNP	G	G	C			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr2:113127775G>C	ENST00000302558.3	-	23	5469	c.5278C>G	c.(5278-5280)Cct>Gct	p.P1760A	RGPD8_ENST00000409750.1_Missense_Mutation_p.P1620A	NM_001164463.1	NP_001157935.1			RANBP2-like and GRIP domain containing 8									p.P1760A(12)		endometrium(4)|kidney(1)|lung(1)|prostate(3)|urinary_tract(1)	10						GAACGGGAAGGATTTTCTTCC	0.308000													4	42					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr7:140453136A>T	ENST00000288602.6	-	15	1859	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333.4	NP_004324.2	P15056	BRAF_HUMAN	v-raf murine sarcoma viral oncogene homolog B	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(15453)|p.V600K(252)|p.V600R(44)|p.V600D(16)|p.V600A(12)|p.V600_K601>E(12)|p.V600G(11)|p.T599_R603>I(2)|p.V600Q(2)|p.V600_S605>EK(1)|p.V600_S605>DV(1)|p.V600_S605>D(1)|p.T599_V600insDFGLAT(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				26	32					0	0	1	0	0
ANGPTL7	10218	broad.mit.edu	37	1	11249916	11249916	+	Missense_Mutation	SNP	C	C	T			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr1:11249916C>T	ENST00000376819.3	+	1	519	c.280C>T	c.(280-282)Cgg>Tgg	p.R94W	MTOR_ENST00000361445.4_Intron	NM_021146.2	NP_066969.1	O43827	ANGL7_HUMAN	angiopoietin-like 7	94					response to oxidative stress|signal transduction	extracellular region	receptor binding	p.R94W(1)		endometrium(2)|kidney(1)|large_intestine(1)|lung(3)|skin(2)|stomach(1)	10	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.000818)|all_lung(284;0.00105)|Colorectal(325;0.0062)|Breast(348;0.0139)|Hepatocellular(190;0.0305)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;1.39e-06)|COAD - Colon adenocarcinoma(227;0.000244)|BRCA - Breast invasive adenocarcinoma(304;0.000294)|Kidney(185;0.000728)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.0072)|READ - Rectum adenocarcinoma(331;0.0487)		CATGGAGTCGCGGCTCACAGA	0.557000													4	34					0	0	1	0	0
UBE4A	9354	broad.mit.edu	37	11	118240215	118240215	+	Missense_Mutation	SNP	G	G	C			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr11:118240215G>C	ENST00000252108.3	+	4	504	c.373G>C	c.(373-375)Gat>Cat	p.D125H	UBE4A_ENST00000431736.2_Missense_Mutation_p.D125H	NM_001204077.1|NM_004788.3	NP_001191006.1|NP_004779.2	Q14139	UBE4A_HUMAN	ubiquitination factor E4A	125					ubiquitin-dependent protein catabolic process	ubiquitin ligase complex	protein binding			autonomic_ganglia(1)|breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(17)|large_intestine(7)|liver(2)|lung(14)|ovary(3)|prostate(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	56	all_hematologic(175;0.046)	Medulloblastoma(222;0.0425)|Breast(348;0.181)|all_hematologic(192;0.196)|all_neural(223;0.234)		BRCA - Breast invasive adenocarcinoma(274;3.28e-05)		AGAGCTAGAAGATCAAGACTG	0.428000													5	42					0	0	1	0	0
STAG3L2	0	broad.mit.edu	37	7	74306378	74306378	+	RNA	DEL	C	C	-			TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr7:74306378delC	ENST00000423186.1	-	0	296							P0CL84	ST3L2_HUMAN								nucleus	binding			breast(1)|central_nervous_system(1)|large_intestine(1)|lung(1)|pancreas(1)	5						GGGCGGGGGGCCCCGCGCTCC	0.731													3	5	---	---	---	---					
FOXE1	2304	broad.mit.edu	37	9	100616701	100616706	+	In_Frame_Del	DEL	GCCGCC	GCCGCC	-	rs11279082		TCGA-L6-A4ET-01A-11D-A257-08	TCGA-L6-A4ET-10A-01D-A25A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	546b97b0-ab82-42a1-bbd2-241523278ec3	ea509942-fcac-486f-ac3d-37457bab29db	g.chr9:100616701_100616706delGCCGCC	ENST00000375123.3	+	1	1166_1171	c.505_510delGCCGCC	c.(505-510)del	p.AA177del		NM_004473.3	NP_004464.2	O00358	FOXE1_HUMAN	forkhead box E1 (thyroid transcription factor 2)	177	Ala-rich.|Poly-Ala.				cell migration|embryonic organ morphogenesis|hair follicle morphogenesis|hard palate development|lens morphogenesis in camera-type eye|negative regulation of transcription from RNA polymerase II promoter|pattern specification process|peripheral nervous system development|pharynx development|positive regulation of transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity|soft palate development|thymus development|thyroid gland development|thyroid hormone generation	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			central_nervous_system(1)|endometrium(1)|lung(2)|upper_aerodigestive_tract(1)	5		Acute lymphoblastic leukemia(62;0.158)				Ggctgccgcagccgccgccgccgccg	0.767													4	8	---	---	---	---					
