Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
VPS13D	55187	broad.mit.edu	37	1	12343708	12343708	+	Missense_Mutation	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:12343708G>A	ENST00000358136.3	+	21	5679	c.5549G>A	c.(5548-5550)gGc>gAc	p.G1850D	VPS13D_ENST00000356315.4_Missense_Mutation_p.G1850D	NM_015378.2	NP_056193.2	Q5THJ4	VP13D_HUMAN	vacuolar protein sorting 13 homolog D (S. cerevisiae)	1850					protein localization					NS(1)|breast(6)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(13)|large_intestine(28)|lung(44)|ovary(5)|pancreas(1)|prostate(8)|skin(4)|upper_aerodigestive_tract(3)|urinary_tract(4)	130	Ovarian(185;0.249)	Lung NSC(185;4.08e-05)|all_lung(284;4.55e-05)|Renal(390;0.000147)|Colorectal(325;0.00058)|Breast(348;0.00093)|Ovarian(437;0.00965)|Hepatocellular(190;0.0202)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0327)|Colorectal(212;4.63e-06)|BRCA - Breast invasive adenocarcinoma(304;0.000289)|COAD - Colon adenocarcinoma(227;0.000801)|Kidney(185;0.00216)|KIRC - Kidney renal clear cell carcinoma(229;0.00544)|STAD - Stomach adenocarcinoma(313;0.012)|READ - Rectum adenocarcinoma(331;0.0476)|Lung(427;0.209)		CCTCCTGAGGGCATTCTGCAC	0.507000													4	115					0	0	1	0	0
NDUFV2	4729	broad.mit.edu	37	18	9124980	9124980	+	Splice_Site	SNP	A	A	G			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr18:9124980A>G	ENST00000400033.1	+	7	704	c.588_splice	c.e7+1	p.Y196_splice	RP11-143J12.2_ENST00000582375.1_RNA|NDUFV2_ENST00000318388.6_Splice_Site_p.Y193_splice|NDUFV2_ENST00000465096.1_3'UTR|RP11-21J18.1_ENST00000579126.1_RNA|RP11-143J12.2_ENST00000583081.1_RNA			P19404	NDUV2_HUMAN	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	193					cardiac muscle tissue development|mitochondrial electron transport, NADH to ubiquinone|nervous system development|transport	mitochondrial respiratory chain complex I	2 iron, 2 sulfur cluster binding|electron carrier activity|metal ion binding|NAD binding|NADH dehydrogenase (ubiquinone) activity			breast(1)|lung(4)|ovary(1)|stomach(1)	7					NADH(DB00157)	GACAATTACTATGTGAGTATT	0.328000													15	23					0	0	1	0	0
NLRP6	171389	broad.mit.edu	37	11	281038	281038	+	Missense_Mutation	SNP	G	G	C			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr11:281038G>C	ENST00000534750.1	+	4	1509	c.1304G>C	c.(1303-1305)gGg>gCg	p.G435A	NLRP6_ENST00000312165.5_Missense_Mutation_p.G435A	NM_001276700.1	NP_001263629.1	P59044	NALP6_HUMAN	NLR family, pyrin domain containing 6	435	NACHT.					cytoplasm	ATP binding			breast(1)|skin(1)|upper_aerodigestive_tract(2)	4		all_cancers(49;1.12e-06)|all_epithelial(84;0.000375)|Breast(177;0.00122)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		all cancers(45;4.28e-28)|Epithelial(43;2.47e-27)|OV - Ovarian serous cystadenocarcinoma(40;4.66e-21)|BRCA - Breast invasive adenocarcinoma(625;3.57e-05)|Lung(200;0.0485)|LUSC - Lung squamous cell carcinoma(625;0.122)		GTAGCCGACGGGCCCCGGTTG	0.667000													11	147					0	0	1	0	0
PRG4	10216	broad.mit.edu	37	1	186276229	186276229	+	Missense_Mutation	SNP	A	A	G			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:186276229A>G	ENST00000445192.2	+	7	1423	c.1378A>G	c.(1378-1380)Aca>Gca	p.T460A	PRG4_ENST00000367484.3_Intron|PRG4_ENST00000367486.3_Missense_Mutation_p.T417A|PRG4_ENST00000367483.4_Missense_Mutation_p.T419A|PRG4_ENST00000367485.4_Missense_Mutation_p.T367A	NM_005807.3	NP_005798.2	Q92954	PRG4_HUMAN	proteoglycan 4	460	59 X 8 AA repeats of K-X-P-X-P-T-T-X.				cell proliferation|immune response	extracellular region	polysaccharide binding|protein binding|scavenger receptor activity	p.T460A(1)		NS(2)|breast(1)|central_nervous_system(1)|endometrium(26)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(12)|lung(33)|prostate(7)|skin(9)|upper_aerodigestive_tract(2)|urinary_tract(1)	102						CAAGGAGCCTACACCCACCAC	0.657000													5	129					0	0	1	0	0
MT-ND5	4540	broad.mit.edu	37	MT	12414	12414	+	Silent	SNP	T	T	C			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chrM:12414T>C	ENST00000361567.2	+	1	78	c.78T>C	c.(76-78)ccT>ccC	p.P26P				P03915	NU5M_HUMAN	mitochondrially encoded NADH dehydrogenase 5	26					mitochondrial electron transport, NADH to ubiquinone|transport	integral to membrane|mitochondrial respiratory chain complex I	NADH dehydrogenase (ubiquinone) activity			breast(4)|endometrium(29)|kidney(33)|pancreas(1)|prostate(7)	74					NADH(DB00157)	CTCGTTAACCCTAACAAAAAA	0.413000													6	167					0	0	1	0	0
AGAP10	728127	broad.mit.edu	37	10	47207813	47207813	+	Splice_Site	SNP	T	T	C			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr10:47207813T>C	ENST00000355232.3	-	5	3482	c.471_splice	c.e5+1	p.H157_splice	AGAP10_ENST00000452145.2_Splice_Site_p.H132_splice|RP11-144G6.12_ENST00000605970.1_RNA|AGAP10_ENST00000413193.2_Splice_Site_p.H228_splice					ArfGAP with GTPase domain, ankyrin repeat and PH domain 10									p.H228R(20)		endometrium(5)|kidney(3)|lung(1)|prostate(2)|urinary_tract(1)	12						TTTACTTACATGGTTTGTACA	0.294000													4	47					0	0	1	0	0
POU2F3	25833	broad.mit.edu	37	11	120169019	120169019	+	Missense_Mutation	SNP	C	C	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr11:120169019C>A	ENST00000260264.4	+	4	218	c.184C>A	c.(184-186)Cat>Aat	p.H62N	POU2F3_ENST00000543440.2_Missense_Mutation_p.H60N	NM_001244682.1	NP_001231611.1	Q9UKI9	PO2F3_HUMAN	POU class 2 homeobox 3	60					negative regulation by host of viral transcription	cytoplasm	sequence-specific DNA binding			large_intestine(5)|lung(7)|ovary(2)|prostate(2)|skin(1)	17		Breast(109;0.0011)|Medulloblastoma(222;0.0425)|Hepatocellular(160;0.0831)|all_neural(223;0.112)		BRCA - Breast invasive adenocarcinoma(274;6.85e-06)		GACCCTCTCCCATCGGCCATG	0.532000													114	163					2.91849e-64	3.18381e-64	1	1	0
CTCFL	140690	broad.mit.edu	37	20	56099163	56099163	+	Silent	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr20:56099163G>A	ENST00000426658.2	-	1	760	c.99C>T	c.(97-99)gaC>gaT	p.D33D	CTCFL_ENST00000433949.2_Silent_p.D33D|CTCFL_ENST00000429804.2_Silent_p.D33D|CTCFL_ENST00000423479.2_Silent_p.D33D|CTCFL_ENST00000422869.2_Silent_p.D33D|CTCFL_ENST00000371196.2_Silent_p.D33D|CTCFL_ENST00000243914.3_Silent_p.D33D|CTCFL_ENST00000539382.1_Intron|CTCFL_ENST00000502686.2_Intron|CTCFL_ENST00000422109.2_Silent_p.D33D|CTCFL_ENST00000432255.2_Silent_p.D33D			Q8NI51	CTCFL_HUMAN	CCCTC-binding factor (zinc finger protein)-like	33					cell cycle|DNA methylation involved in gamete generation|histone methylation|positive regulation of transcription, DNA-dependent|regulation of gene expression by genetic imprinting|regulation of histone H3-K4 methylation|transcription, DNA-dependent	cytoplasm|nucleus	histone binding|sequence-specific DNA binding|transcription regulatory region DNA binding|zinc ion binding			NS(1)|breast(1)|cervix(2)|endometrium(6)|kidney(4)|large_intestine(9)|lung(28)|ovary(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	58	Lung NSC(12;0.00132)|all_lung(29;0.00433)|Melanoma(10;0.242)		BRCA - Breast invasive adenocarcinoma(13;3.95e-12)|Epithelial(14;3.41e-08)|all cancers(14;2.09e-07)			TGCACACTCCGTCTTTTTCCT	0.537000													7	274					0	0	1	0	0
RP11-156P1.3	0	broad.mit.edu	37	17	45127107	45127107	+	RNA	SNP	C	C	G	rs147409399	by1000genomes	TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr17:45127107C>G	ENST00000575173.1	-	0	418																											CCTTCGTTCACCCAAGAGCAT	0.592000													4	78					0	0	1	0	0
IL1RAPL2	26280	broad.mit.edu	37	X	104993041	104993041	+	Silent	SNP	C	C	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chrX:104993041C>T	ENST00000372582.1	+	9	1893	c.1137C>T	c.(1135-1137)aaC>aaT	p.N379N	IL1RAPL2_ENST00000485671.1_3'UTR|IL1RAPL2_ENST00000344799.4_Silent_p.N379N	NM_017416.1	NP_059112.1	Q9NP60	IRPL2_HUMAN	interleukin 1 receptor accessory protein-like 2	379					central nervous system development|innate immune response	integral to membrane	interleukin-1, Type II, blocking receptor activity			breast(3)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(14)|lung(23)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	49						AATGCTACAACATTGAATTGA	0.418000													27	52					0	0	1	0	0
CNTN5	53942	broad.mit.edu	37	11	100064362	100064362	+	Silent	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr11:100064362G>A	ENST00000524871.1	+	15	2141	c.1851G>A	c.(1849-1851)gaG>gaA	p.E617E	CNTN5_ENST00000418526.2_Silent_p.E543E|CNTN5_ENST00000527185.1_Silent_p.E617E|CNTN5_ENST00000524560.1_3'UTR|CNTN5_ENST00000279463.3_Silent_p.E617E|CNTN5_ENST00000528682.1_Silent_p.E617E	NM_014361.3	NP_055176.1	O94779	CNTN5_HUMAN	contactin 5	617	Ig-like C2-type 6.				cell adhesion	anchored to membrane|plasma membrane	protein binding			NS(2)|breast(2)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(12)|lung(38)|ovary(2)|pancreas(2)|prostate(2)|skin(7)|upper_aerodigestive_tract(2)|urinary_tract(1)	81		all_hematologic(158;1.22e-05)|Acute lymphoblastic leukemia(157;3.81e-05)|Melanoma(852;0.219)		BRCA - Breast invasive adenocarcinoma(274;0.00146)|KIRC - Kidney renal clear cell carcinoma(183;0.156)|Kidney(183;0.196)		TTGATTTCGAGGAAGAGGGTG	0.378000													22	35					0	0	1	0	0
HERC2P3	0	broad.mit.edu	37	15	20657756	20657756	+	RNA	SNP	A	A	G			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr15:20657756A>G	ENST00000428453.1	-	0	2202																				central_nervous_system(1)|endometrium(11)|kidney(2)|large_intestine(1)|lung(14)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	35						ATGGTCCCCAAGCTCGGTCCC	0.557000													4	70					0	0	1	0	0
TBC1D3P2	0	broad.mit.edu	37	17	60342186	60342186	+	RNA	SNP	T	T	C	rs79096325		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr17:60342186T>C	ENST00000581291.1	-	0	1967																				breast(2)|kidney(1)|lung(2)	5						GCTGGGGGTGTTGGGAGGGGC	0.498000													4	23					0	0	1	0	0
NRAS	4893	broad.mit.edu	37	1	115256529	115256529	+	Missense_Mutation	SNP	T	T	C	rs11554290		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:115256529T>C	ENST00000369535.4	-	3	435	c.182A>G	c.(181-183)cAa>cGa	p.Q61R		NM_002524.4	NP_002515.1	P01111	RASN_HUMAN	neuroblastoma RAS viral (v-ras) oncogene homolog	61			Q -> K (in neuroblastoma cell).|Q -> R (in lung carcinoma cell and melanoma; dbSNP:rs11554290).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	Golgi membrane|plasma membrane	GTP binding|GTPase activity	p.Q61R(817)|p.Q61L(175)|p.Q61P(23)|p.Q61K(1)		NS(134)|adrenal_gland(9)|autonomic_ganglia(9)|biliary_tract(6)|bone(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(11)|eye(3)|haematopoietic_and_lymphoid_tissue(1115)|kidney(3)|large_intestine(105)|liver(10)|lung(42)|meninges(2)|ovary(7)|pancreas(5)|prostate(8)|skin(1144)|soft_tissue(37)|stomach(5)|testis(8)|thyroid(359)|upper_aerodigestive_tract(28)|urinary_tract(13)	3085	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GTACTCTTCTTGTCCAGCTGT	0.458000	Q61L(C3A_LIVER)|Q61L(HEPG2_LIVER)|Q61L(HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(IPC298_SKIN)|Q61L(KMS21BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MELJUSO_SKIN)|Q61L(MHHES1_BONE)|Q61L(MOLP8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61P(TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(HT1197_URINARY_TRACT)|Q61R(KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(KU1919_URINARY_TRACT)|Q61R(NCIH2347_LUNG)|Q61R(ONS76_CENTRAL_NERVOUS_SYSTEM)|Q61R(SKMEL2_SKIN)|Q61R(SW1271_LUNG)|Q61R(TT2609C02_THYROID)	50	Mis		"""melanoma, MM, AML, thyroid"""				Noonan syndrome	TSP Lung(23;0.16)|Multiple Myeloma(1;<1E-6)			69	80					0	0	1	0	0
KRTAP1-5	83895	broad.mit.edu	37	17	39183145	39183145	+	Missense_Mutation	SNP	A	A	G			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr17:39183145A>G	ENST00000361883.5	-	1	309	c.263T>C	c.(262-264)aTc>aCc	p.I88T		NM_031957.1	NP_114163.1	Q9BYS1	KRA15_HUMAN	keratin associated protein 1-5	88	15 X 5 AA repeats of C-C-[QEPVRC]- [TPIVLE]-[SRHVP].					keratin filament		p.I88T(11)		central_nervous_system(1)|endometrium(2)|kidney(1)|lung(9)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(2)	17		Breast(137;0.00043)	STAD - Stomach adenocarcinoma(17;0.000371)			GCAGGAGCTGATCTGGCAGCA	0.632000													6	64					0	0	1	0	0
ACTL9	284382	broad.mit.edu	37	19	8808059	8808059	+	Silent	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr19:8808059G>A	ENST00000324436.3	-	1	1113	c.993C>T	c.(991-993)cgC>cgT	p.R331R		NM_178525.3	NP_848620.2	Q8TC94	ACTL9_HUMAN	actin-like 9	331						cytoplasm|cytoskeleton				NS(2)|central_nervous_system(1)|endometrium(2)|kidney(2)|large_intestine(8)|lung(15)|pancreas(1)|prostate(3)|skin(1)|urinary_tract(1)	36						CCAAGTCCGCGCGCATCTCCA	0.667000													39	45					0	0	1	0	0
ALPK2	115701	broad.mit.edu	37	18	56203904	56203904	+	Missense_Mutation	SNP	G	G	A	rs140868694	byFrequency	TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr18:56203904G>A	ENST00000361673.3	-	5	3728	c.3515C>T	c.(3514-3516)aCg>aTg	p.T1172M	RP11-1151B14.4_ENST00000591360.1_RNA	NM_052947.3	NP_443179.3	Q86TB3	ALPK2_HUMAN	alpha-kinase 2	1172							ATP binding|protein serine/threonine kinase activity			NS(1)|central_nervous_system(3)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(13)|lung(33)|ovary(7)|prostate(1)|skin(10)|upper_aerodigestive_tract(2)	84						TGAGTGGGCCGTGGGCACCAA	0.577000													4	110					0	0	1	0	0
GABRE	2564	broad.mit.edu	37	X	151138673	151138673	+	Silent	SNP	C	C	A	rs76574542		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chrX:151138673C>A	ENST00000370325.1	-	2	311	c.258G>T	c.(256-258)ctG>ctT	p.L86L	GABRE_ENST00000393914.3_5'UTR|GABRE_ENST00000370328.3_Silent_p.L86L			P78334	GBRE_HUMAN	gamma-aminobutyric acid (GABA) A receptor, epsilon	86					gamma-aminobutyric acid signaling pathway	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	chloride channel activity|extracellular ligand-gated ion channel activity|GABA-A receptor activity			breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(9)|ovary(2)|skin(1)	27	Acute lymphoblastic leukemia(192;6.56e-05)					TGCCAGGGCGCAGTTTGTGGT	0.532000													44	82					1.02687e-29	1.08727e-29	1	1	0
RPS12	6206	broad.mit.edu	37	6	133138134	133138134	+	Silent	SNP	C	C	G	rs146638149		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr6:133138134C>G	ENST00000230050.3	+	5	480	c.270C>G	c.(268-270)ggC>ggG	p.G90G		NM_001016.3	NP_001007.2	P25398	RS12_HUMAN	ribosomal protein S12	90					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic small ribosomal subunit	structural constituent of ribosome			endometrium(1)|kidney(13)|lung(3)|urinary_tract(1)	18	Breast(56;0.214)			OV - Ovarian serous cystadenocarcinoma(155;0.00284)|GBM - Glioblastoma multiforme(226;0.0256)		AATGGGTAGGCCTTTGTAAAA	0.358000													6	68					0	0	1	0	0
SIPA1L2	57568	broad.mit.edu	37	1	232649623	232649623	+	Missense_Mutation	SNP	C	C	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:232649623C>T	ENST00000366630.1	-	2	1821	c.1463G>A	c.(1462-1464)cGc>cAc	p.R488H	SIPA1L2_ENST00000262861.4_Missense_Mutation_p.R488H			Q9P2F8	SI1L2_HUMAN	signal-induced proliferation-associated 1 like 2	488					regulation of small GTPase mediated signal transduction	intracellular	GTPase activator activity			NS(1)|breast(5)|central_nervous_system(2)|endometrium(15)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(13)|lung(49)|ovary(2)|pancreas(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	103		all_cancers(173;0.00605)|Prostate(94;0.128)|all_epithelial(177;0.186)				GAAGAATTTGCGGTAATAATA	0.453000													4	146					0	0	1	0	0
ARHGEF17	9828	broad.mit.edu	37	11	73071517	73071517	+	Silent	SNP	C	C	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr11:73071517C>T	ENST00000263674.3	+	11	4709	c.4359C>T	c.(4357-4359)ttC>ttT	p.F1453F		NM_014786.3	NP_055601.2	Q96PE2	ARHGH_HUMAN	Rho guanine nucleotide exchange factor (GEF) 17	1453					actin cytoskeleton organization|apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol	Rho guanyl-nucleotide exchange factor activity			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(15)|ovary(2)|skin(2)	32						TTTTTGAGTTCCCTCACCCTG	0.607000													59	83					0	0	1	0	0
ANKRD36BP2	0	broad.mit.edu	37	2	89084114	89084114	+	RNA	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr2:89084114G>A	ENST00000393525.3	+	0	576																											TTGCTTTTCAGTGTCTTCTCA	0.313000													4	82					0	0	1	0	0
CYLD	1540	broad.mit.edu	37	16	50828308	50828308	+	Nonsense_Mutation	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr16:50828308G>A	ENST00000540145.1	+	18	3070	c.2655G>A	c.(2653-2655)tgG>tgA	p.W885*	CYLD_ENST00000311559.9_Nonsense_Mutation_p.W885*|CYLD_ENST00000564326.1_Nonsense_Mutation_p.W882*|CYLD_ENST00000566206.1_Nonsense_Mutation_p.W882*|CYLD_ENST00000427738.3_Nonsense_Mutation_p.W885*|CYLD_ENST00000398568.2_Nonsense_Mutation_p.W882*|RP11-327F22.4_ENST00000575917.1_RNA|CYLD_ENST00000569418.1_Nonsense_Mutation_p.W882*|CYLD_ENST00000568704.2_Nonsense_Mutation_p.W700*|RP11-327F22.4_ENST00000564510.1_RNA			Q9NQC7	CYLD_HUMAN	cylindromatosis (turban tumor syndrome)	885					cell cycle|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of NF-kappaB import into nucleus|negative regulation of NF-kappaB transcription factor activity|negative regulation of type I interferon production|protein K63-linked deubiquitination|regulation of microtubule cytoskeleton organization|regulation of mitotic cell cycle|translation|ubiquitin-dependent protein catabolic process|Wnt receptor signaling pathway	cytosol|extrinsic to internal side of plasma membrane|microtubule|perinuclear region of cytoplasm|ribosome	proline-rich region binding|protein kinase binding|structural constituent of ribosome|ubiquitin thiolesterase activity|ubiquitin-specific protease activity|zinc ion binding			central_nervous_system(4)|endometrium(1)|haematopoietic_and_lymphoid_tissue(4)|kidney(3)|large_intestine(9)|lung(17)|pancreas(1)|skin(22)|upper_aerodigestive_tract(1)	62		all_cancers(37;0.0156)				ATTCTGCCTGGCTCTTCTTTG	0.483000			"""Mis, N, F, S"""		cylindroma	cylindroma			Multiple Trichoepithelioma, Familial;Familial Cylindromatosis				65	109					0	0	1	0	0
HLA-A	3105	broad.mit.edu	37	6	29910693	29910693	+	Missense_Mutation	SNP	A	A	G	rs41559716	by1000genomes	TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr6:29910693A>G	ENST00000396634.1	+	4	574	c.233A>G	c.(232-234)cAg>cGg	p.Q78R	HLA-A_ENST00000376809.5_Missense_Mutation_p.Q78R|HLA-A_ENST00000376806.5_Missense_Mutation_p.Q78R|HLA-A_ENST00000376802.2_Missense_Mutation_p.Q78R			P30443	1A01_HUMAN	major histocompatibility complex, class I, A	78	Alpha-1.				antigen processing and presentation of peptide antigen via MHC class I|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of immune response|type I interferon-mediated signaling pathway	integral to plasma membrane|MHC class I protein complex	MHC class I receptor activity	p.Q78R(2)		central_nervous_system(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	30						TGGATAGAGCAGGAGGGGCCG	0.657000									Osteosarcoma, Familial Clustering of;Naso-/Oropharyngeal/Laryngeal Cancer, Familial Clustering of;Melanoma, Familial Clustering of;Lichen Sclerosis et Atrophicus, Familial Clustering of	Multiple Myeloma(9;0.094)			6	31					0	0	1	0	0
KMT2C	58508	broad.mit.edu	37	7	151932951	151932951	+	Missense_Mutation	SNP	C	C	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr7:151932951C>T	ENST00000355193.2	-	16	2938	c.2720G>A	c.(2719-2721)cGa>cAa	p.R907Q	KMT2C_ENST00000262189.6_Missense_Mutation_p.R907Q					lysine (K)-specific methyltransferase 2C																		TGACCTGCCTCGGCCACCTCG	0.488000													5	108					0	0	1	0	0
SLCO1B3	28234	broad.mit.edu	37	12	21014004	21014004	+	Missense_Mutation	SNP	G	G	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr12:21014004G>T	ENST00000381545.3	+	6	632	c.413G>T	c.(412-414)aGt>aTt	p.S138I	SLCO1B7_ENST00000554957.1_Intron|SLCO1B3_ENST00000553473.1_Missense_Mutation_p.S138I|LST3_ENST00000540229.1_Missense_Mutation_p.S138I|SLCO1B3_ENST00000261196.2_Missense_Mutation_p.S138I|LST3_ENST00000381541.3_Intron	NM_019844.3	NP_062818.1	Q9NPD5	SO1B3_HUMAN	solute carrier organic anion transporter family, member 1B3	138					bile acid metabolic process|sodium-independent organic anion transport	basolateral plasma membrane|cytoplasm|integral to plasma membrane	bile acid transmembrane transporter activity|organic anion transmembrane transporter activity			breast(3)|central_nervous_system(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(12)|lung(23)|ovary(2)|prostate(2)|skin(6)|upper_aerodigestive_tract(4)|urinary_tract(2)	63	Esophageal squamous(101;0.149)					TCAACATCAAGTTTATCAACC	0.284000													4	112					0.00024832	0.00024832	1	1	0
FRG1B	0	broad.mit.edu	37	20	29628283	29628283	+	Silent	SNP	G	G	C			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr20:29628283G>C	ENST00000278882.3	+	6	665	c.285G>C	c.(283-285)ggG>ggC	p.G95G	FRG1B_ENST00000439954.2_Silent_p.G100G|FRG1B_ENST00000358464.4_Silent_p.G95G														p.G95G(4)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						ATGAAGCAGGGGACATAGAAG	0.378000													5	103					0	0	1	0	0
MMACHC	25974	broad.mit.edu	37	1	45974755	45974755	+	Silent	SNP	C	C	G			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:45974755C>G	ENST00000401061.4	+	4	997	c.717C>G	c.(715-717)ccC>ccG	p.P239P		NM_015506.2	NP_056321.2	Q9Y4U1	MMAC_HUMAN	methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria	239							cobalamin binding			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(1)|lung(2)|upper_aerodigestive_tract(1)	8	Acute lymphoblastic leukemia(166;0.155)				Cyanocobalamin(DB00115)|Hydroxocobalamin(DB00200)	TGGCTCAGCCCTCAGAGAAGC	0.622000													6	113					0	0	1	0	0
COG3	83548	broad.mit.edu	37	13	46066331	46066331	+	Missense_Mutation	SNP	A	A	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr13:46066331A>T	ENST00000349995.5	+	11	1245	c.1133A>T	c.(1132-1134)cAg>cTg	p.Q378L	COG3_ENST00000465942.1_3'UTR	NM_031431.3	NP_113619.2	Q96JB2	COG3_HUMAN	component of oligomeric golgi complex 3	378					ER to Golgi vesicle-mediated transport|intra-Golgi vesicle-mediated transport|intracellular protein transport|protein glycosylation|protein localization to organelle|protein stabilization|retrograde vesicle-mediated transport, Golgi to ER	cis-Golgi network|Golgi cisterna membrane|Golgi transport complex	protein binding|protein transporter activity			breast(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(8)|prostate(2)|skin(2)|stomach(1)	24		Lung NSC(96;0.000145)|Breast(56;0.000596)|Prostate(109;0.00438)|Hepatocellular(98;0.0207)|Lung SC(185;0.0262)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;0.000124)		CATGTCTGCCAGGATGAACAC	0.373000													21	27					0	0	1	0	0
MRPL28	10573	broad.mit.edu	37	16	417713	417713	+	Nonsense_Mutation	SNP	C	C	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr16:417713C>A	ENST00000199706.8	-	6	768	c.733G>T	c.(733-735)Gag>Tag	p.E245*	MRPL28_ENST00000389675.2_Nonsense_Mutation_p.E245*|MRPL28_ENST00000429738.1_Intron	NM_006428.4	NP_006419.2	Q13084	RM28_HUMAN	mitochondrial ribosomal protein L28	245					translation	mitochondrial ribosome	protein binding|structural constituent of ribosome			breast(1)|kidney(1)|lung(1)|ovary(1)|prostate(1)	5		Hepatocellular(16;0.000105)|Lung NSC(18;0.0324)|all_lung(18;0.064)				ACCGCCGGCTCTGACAGTGCC	0.617000													23	35					1.2476e-16	1.28324e-16	1	1	0
FRG1B	0	broad.mit.edu	37	20	29628300	29628300	+	Missense_Mutation	SNP	G	G	A			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr20:29628300G>A	ENST00000278882.3	+	6	682	c.302G>A	c.(301-303)aGt>aAt	p.S101N	FRG1B_ENST00000439954.2_Missense_Mutation_p.S106N|FRG1B_ENST00000358464.4_Missense_Mutation_p.S101N														p.S101N(2)		endometrium(10)|kidney(21)|lung(3)|pancreas(1)|prostate(9)|urinary_tract(9)	53						GAAGCAAAAAGTAAAACAGCA	0.358000													5	88					0	0	1	0	0
ERBB3	2065	broad.mit.edu	37	12	56481627	56481627	+	Missense_Mutation	SNP	C	C	T			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr12:56481627C>T	ENST00000267101.3	+	6	1102	c.662C>T	c.(661-663)cCc>cTc	p.P221L	ERBB3_ENST00000450146.2_Intron|ERBB3_ENST00000415288.2_Missense_Mutation_p.P162L	NM_001982.3	NP_001973.2	P21860	ERBB3_HUMAN	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3	221					cranial nerve development|heart development|negative regulation of cell adhesion|negative regulation of neuron apoptosis|negative regulation of secretion|negative regulation of signal transduction|neuron apoptosis|phosphatidylinositol 3-kinase cascade|positive regulation of phosphatidylinositol 3-kinase cascade|regulation of cell proliferation|Schwann cell differentiation|transmembrane receptor protein tyrosine kinase signaling pathway|wound healing	basolateral plasma membrane|extracellular space|integral to plasma membrane|receptor complex	ATP binding|growth factor binding|protein heterodimerization activity|protein homodimerization activity|protein tyrosine kinase activator activity|receptor signaling protein tyrosine kinase activity|transmembrane receptor protein tyrosine kinase activity			central_nervous_system(2)|lung(3)|ovary(1)|skin(1)|stomach(1)	8			OV - Ovarian serous cystadenocarcinoma(18;0.112)			TGCTTTGGGCCCAACCCCAAC	0.542000													6	93					0	0	1	0	0
MAML3	55534	broad.mit.edu	37	4	140811123	140811123	+	Silent	SNP	T	T	C	rs62344939		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr4:140811123T>C	ENST00000509479.2	-	2	2323	c.1467A>G	c.(1465-1467)caA>caG	p.Q489Q	MAML3_ENST00000398940.1_Silent_p.Q28Q|MAML3_ENST00000327122.5_Silent_p.Q333Q	NM_018717.4	NP_061187.2	Q96JK9	MAML3_HUMAN	mastermind-like 3 (Drosophila)	489	Gln-rich.				Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	transcription coactivator activity			breast(1)|endometrium(7)|kidney(2)|large_intestine(1)|lung(9)|ovary(1)|prostate(2)|urinary_tract(2)	25	all_hematologic(180;0.162)					gctgctgctgttgctgttgct	0.547000													4	29					0	0	1	0	0
ANKRD20A12P	0	broad.mit.edu	37	1	142716575	142716578	+	RNA	DEL	AAAC	AAAC	-			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr1:142716575_142716578delAAAC	ENST00000595144.1	-	0	418																											catctcagaaaaacaaacaaacaa	0.422													8	201	---	---	---	---					
RP11-551L14.1	0	broad.mit.edu	37	12	31269805	31269806	+	RNA	INS	-	-	AAG	rs67001718		TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr12:31269805_31269806insAAG	ENST00000542490.1	-	0	52																				central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(2)|lung(25)|prostate(3)|stomach(3)|urinary_tract(1)	41						CAATATTCCTCAAACTTCTCTT	0.307													3	4	---	---	---	---					
UPF3AP2	0	broad.mit.edu	37	17	20279655	20279655	+	RNA	DEL	T	T	-			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr17:20279655delT	ENST00000578315.1	-	0	51																											tctgtctctcttttttttttt	0.383													4	3	---	---	---	---					
PALM	5064	broad.mit.edu	37	19	746801	746801	+	Frame_Shift_Del	DEL	G	G	-			TCGA-QD-A8IV-01A-11D-A397-08	TCGA-QD-A8IV-10A-01D-A39A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0da85938-d959-4f4f-94a0-33a40bddf048	82853bee-af8e-4007-8556-b953a6163a97	g.chr19:746801delG	ENST00000264560.7	+	8	1213	c.1019delG	c.(1018-1020)tcfs	p.C340fs	PALM_ENST00000338448.5_Frame_Shift_Del_p.C384fs|PALM_ENST00000606643.1_3'UTR	NM_001040134.1	NP_001035224.1	O75781	PALM_HUMAN	paralemmin	384					cellular component movement|negative regulation of adenylate cyclase activity|negative regulation of dopamine receptor signaling pathway|positive regulation of filopodium assembly|regulation of cell shape	cytoplasmic membrane-bounded vesicle|filopodium membrane|integral to plasma membrane				endometrium(2)|large_intestine(1)|lung(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	11		all_epithelial(18;2.19e-21)|Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;3.55e-06)|all_lung(49;5.41e-06)|Breast(49;4.08e-05)|Hepatocellular(1079;0.137)|Renal(1328;0.228)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)|Lung(535;0.201)		TGTAAATGCTGCTCCATCATG	0.706													2	4	---	---	---	---					
