feature type start end label R G B shape direction protein Name=BRCA2; Synonyms=FACD, FANCD1; 1 3418 Name=BRCA2; Synonyms=FACD, FANCD1; 0.7 0.9 0.9 - - domain Interaction with PALB2. 1 40 Interaction with PALB2. 0.76 0.55 0.75 - - domain Interaction with NPM1. {ECO:0000269|PubMed:21084279}. 639 1000 Interaction with NPM1. {ECO:0000269|PubMed:21084279}. 0.62 0.38 0.46 - - domain Interaction with POLH. {ECO:0000269|PubMed:24485656}. 1338 1781 Interaction with POLH. {ECO:0000269|PubMed:24485656}. 0.6 0.66 0.4 - - domain Required for stimulation of POLH DNA polymerization activity. 1410 1595 Required for stimulation of POLH DNA polymerization activity. 0.23 0.51 0.7 - - domain Interaction with FANCD2. 2350 2545 Interaction with FANCD2. 0.2 0.5 0.39 - - domain Interaction with SEM1. {ECO:0000269|PubMed:10373512, ECO:0000269|PubMed:16205630}. 2481 2832 Interaction with SEM1. {ECO:0000269|PubMed:10373512, ECO:0000269|PubMed:16205630}. 0.24 0.79 0.32 - - domain Nuclear export signal; masked by interaction with SEM1. {ECO:0000269|PubMed:24013206}. 2682 2698 Nuclear export signal; masked by interaction with SEM1. {ECO:0000269|PubMed:24013206}. 0.45 0.69 0.66 - - mutation Frame_Shift_Del 1203 1203 p.S1203fs 1.0 0.0 0.0 square up mutation Nonsense_Mutation 1812 1812 p.E1812* 1.0 0.0 0.0 triangle up mutation Frame_Shift_Ins 2150 2150 p.K2150fs 1.0 0.0 0.0 square up mutation Frame_Shift_Ins 2524 2524 p.K2524fs 1.0 0.0 0.0 square up mutation Missense_Mutation 2678 2678 p.R2678T 1.0 1.0 0.0 circle up