feature	type	start	end	label	R	G	B	shape	direction
protein	Name=TP53; Synonyms=P53;	1	393	Name=TP53; Synonyms=P53;	0.7	0.9	0.9	-	-
domain	DNA-binding (experimentally determined)	102	292	DNA-binding (experimentally determined)	0.77	0.34	0.51	-	-
domain	Interaction with CCAR2. {ECO:0000269|PubMed:25732823}.	1	320	Interaction with CCAR2. {ECO:0000269|PubMed:25732823}.	0.26	0.49	0.32	-	-
domain	Interaction with HRMT1L2. {ECO:0000269|PubMed:15186775}.	1	83	Interaction with HRMT1L2. {ECO:0000269|PubMed:15186775}.	0.39	0.77	0.51	-	-
domain	Transcription activation (acidic).	1	44	Transcription activation (acidic).	0.61	0.71	0.21	-	-
domain	Interaction with WWOX.	66	110	Interaction with WWOX.	0.32	0.77	0.21	-	-
domain	Interaction with HIPK1. {ECO:0000250}.	100	370	Interaction with HIPK1. {ECO:0000250}.	0.22	0.42	0.76	-	-
domain	Required for interaction with ZNF385A. {ECO:0000269|PubMed:17719541}.	100	300	Required for interaction with ZNF385A. {ECO:0000269|PubMed:17719541}.	0.77	0.51	0.75	-	-
domain	Required for interaction with FBXO42. {ECO:0000269|PubMed:19509332}.	113	236	Required for interaction with FBXO42. {ECO:0000269|PubMed:19509332}.	0.56	0.34	0.24	-	-
domain	Interaction with AXIN1. {ECO:0000250}.	116	292	Interaction with AXIN1. {ECO:0000250}.	0.5	0.39	0.59	-	-
domain	Interaction with the 53BP2 SH3 domain.	241	248	Interaction with the 53BP2 SH3 domain.	0.26	0.74	0.76	-	-
domain	Interaction with E4F1. {ECO:0000269|PubMed:10644996}.	256	294	Interaction with E4F1. {ECO:0000269|PubMed:10644996}.	0.66	0.62	0.49	-	-
domain	Interaction with DNA.	273	280	Interaction with DNA.	0.26	0.21	0.23	-	-
domain	Interaction with CARM1. {ECO:0000269|PubMed:15186775}.	300	393	Interaction with CARM1. {ECO:0000269|PubMed:15186775}.	0.24	0.24	0.52	-	-
domain	Interaction with HIPK2.	319	360	Interaction with HIPK2.	0.8	0.49	0.27	-	-
domain	Oligomerization.	325	356	Oligomerization.	0.68	0.22	0.77	-	-
domain	Interaction with USP7.	359	363	Interaction with USP7.	0.96	0	0.61	-	-
domain	Basic (repression of DNA-binding).	368	387	Basic (repression of DNA-binding).	0.82	0.65	0	-	-
domain	TADI.	17	25	TADI.	0.94	0.92	0	-	-
domain	TADII.	48	56	TADII.	0	0.86	0.73	-	-
domain	Bipartite nuclear localization signal.	305	321	Bipartite nuclear localization signal.	0.81	0	0.96	-	-
domain	Nuclear export signal.	339	350	Nuclear export signal.	0	0.65	0.98	-	-
domain	[KR]-[STA]-K motif.	370	372	[KR]-[STA]-K motif.	0.62	0.9	0	-	-
mutation	Frame_Shift_Del	349	349	p.E349fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	349	349	p.E349*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	342	342	p.R342*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	339	339	p.E339*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	339	339	p.E339*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	337	337	p.R337L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	337	337	p.R337P	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	331	331	p.Q331*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Ins	311	311	p.N311fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	306	306	p.R306*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	285	285	p.285_286EE>D*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	285	285	p.E285K	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	283	283	p.R283fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	282	282	p.R282P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	280	280	p.R280K	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	280	280	p.R280fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	279	279	p.G279E	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	276	276	p.A276G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	275	275	p.C275Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	275	275	p.C275Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	274	274	p.V274F	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	274	274	p.V274F	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	273	273	p.R273L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	273	273	p.R273L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	273	273	p.R273P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	273	273	p.R273C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	272	272	p.V272L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	272	272	p.V272L	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	271	271	p.E271*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	267	267	p.R267P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	267	267	p.R267P	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	266	266	p.G266*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	254	254	p.I254N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	249	249	p.R249S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	249	249	p.R249S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	248	248	p.R248L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	248	248	p.R248Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	245	245	p.G245D	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	245	245	p.G245C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	245	245	p.G245R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	243	243	p.243_244MG>IC	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	240	240	p.S240R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	234	234	p.Y234C	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	221	221	p.E221*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	220	220	p.Y220C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	220	220	p.Y220C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	213	213	p.R213L	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	213	213	p.R213*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	205	205	p.Y205C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	205	205	p.Y205F	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	204	204	p.E204*	1.0	0.0	0.0	triangle	up
mutation	In_Frame_Del	201	201	p.LR201del	0.0	0.0	1.0	square	up
mutation	Missense_Mutation	195	195	p.I195T	1.0	1.0	0.0	circle	up
mutation	Splice_Site	188	188	p.L188fs	0.6	0.0	0.6	inv_triangle	up
mutation	Nonsense_Mutation	180	180	p.E180*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	180	180	p.E180*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	179	179	p.H179R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	179	179	p.H179Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	176	176	p.C176W	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	176	176	p.C176Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	175	175	p.R175H	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	175	175	p.R175H	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	164	164	p.K164*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	163	163	p.Y163C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	161	161	p.A161T	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	158	158	p.R158P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	158	158	p.R158L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	158	158	p.R158P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	158	158	p.R158L	1.0	1.0	0.0	circle	up
mutation	In_Frame_Ins	157	157	p.157_158insV	0.0	0.0	1.0	square	up
mutation	Missense_Mutation	157	157	p.V157F	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	157	157	p.V157F	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	154	154	p.G154fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	154	154	p.G154V	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	143	143	p.V143fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	151	151	p.P151S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	148	148	p.D148H	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	147	147	p.V147fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	138	138	p.A138P	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	136	136	p.Q136*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	132	132	p.K132*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	131	131	p.N131I	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.L130V	1.0	1.0	0.0	circle	up
mutation	Splice_Site	125	125	p.T125T	0.6	0.0	0.6	inv_triangle	up
mutation	Missense_Mutation	120	120	p.K120Q	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	118	118	p.T118fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	107	107	p.Y107*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	105	105	p.G105R	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	93	93	p.L93fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	91	91	p.W91fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	85	85	p.P85fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	84	84	p.A84fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	73	73	p.V73fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	68	68	p.E68*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	58	58	p.P58fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	56	56	p.E56*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	53	53	p.W53*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	53	53	p.W53*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	49	49	p.D49fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	35	35	p.L35fs	1.0	0.0	0.0	square	up