feature type start end label R G B shape direction protein Name=NOTCH1; Synonyms=TAN1; 1 2555 Name=NOTCH1; Synonyms=TAN1; 0.7 0.9 0.9 - - domain Neurogenic locus notch homolog protein 1. 19 2555 Neurogenic locus notch homolog protein 1. 0.25 0.67 0.67 - - domain Notch 1 extracellular truncation. {ECO:0000250}. 1721 2555 Notch 1 extracellular truncation. {ECO:0000250}. 0.37 0.65 0.28 - - domain Notch 1 intracellular domain. {ECO:0000250}. 1754 2555 Notch 1 intracellular domain. {ECO:0000250}. 0.26 0.35 0.37 - - domain Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 420 421 Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 0.58 0.23 0.53 - - domain Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 448 452 Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 0.58 0.23 0.53 - - domain HIF1AN-binding. {ECO:0000250}. 1947 1955 HIF1AN-binding. {ECO:0000250}. 0.64 0.54 0.38 - - domain HIF1AN-binding. {ECO:0000250}. 2014 2022 HIF1AN-binding. {ECO:0000250}. 0.64 0.54 0.38 - - mutation Missense_Mutation 2354 2354 p.L2354H 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 2102 2102 p.Q2102* 1.0 0.0 0.0 triangle up mutation Silent 1791 1791 p.S1791S 0.8 0.8 0.8 circle up mutation Splice_Site 1673 1673 p.X1673_splice 0.6 0.0 0.6 inv_triangle up mutation Splice_Site 1673 1673 p.X1673_splice 0.6 0.0 0.6 inv_triangle up mutation Missense_Mutation 1546 1546 p.D1546Y 1.0 1.0 0.0 circle up mutation Missense_Mutation 974 974 p.G974R 1.0 1.0 0.0 circle up mutation Missense_Mutation 863 863 p.G863V 1.0 1.0 0.0 circle up mutation Missense_Mutation 745 745 p.W745C 1.0 1.0 0.0 circle up mutation Silent 720 720 p.C720C 0.8 0.8 0.8 circle up mutation Splice_Site 635 635 p.X635_splice 0.6 0.0 0.6 inv_triangle up mutation Nonsense_Mutation 439 439 p.Q439* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 377 377 p.I377M 1.0 1.0 0.0 circle up mutation Missense_Mutation 376 376 p.C376W 1.0 1.0 0.0 circle up mutation Frame_Shift_Del 324 324 p.V324Afs*305 1.0 0.0 0.0 square up