feature type start end label R G B shape direction protein Name=DHX9 {ECO:0000312|HGNC:HGNC:2750}; Synonyms=DDX9 {ECO:0000312|HGNC:HGNC:2750}, LKP, NDH2; 1 1270 Name=DHX9 {ECO:0000312|HGNC:HGNC:2750}; Synonyms=DDX9 {ECO:0000312|HGNC:HGNC:2750}, LKP, NDH2; 0.7 0.9 0.9 - - domain ATP. {ECO:0000244|PDB:3LLM, ECO:0000269|PubMed:11416126, ECO:0000269|PubMed:20510246}. 411 419 ATP. {ECO:0000244|PDB:3LLM, ECO:0000269|PubMed:11416126, ECO:0000269|PubMed:20510246}. 0.71 0.77 0.22 - - domain Interaction with CREBBP. {ECO:0000269|PubMed:9323138}. 1 250 Interaction with CREBBP. {ECO:0000269|PubMed:9323138}. 0.56 0.49 0.79 - - domain siRNA-binding. {ECO:0000244|PDB:3VYY, ECO:0000269|PubMed:23361462}. 5 9 siRNA-binding. {ECO:0000244|PDB:3VYY, ECO:0000269|PubMed:23361462}. 0.24 0.38 0.42 - - domain siRNA-binding. {ECO:0000244|PDB:3VYY, ECO:0000269|PubMed:23361462}. 53 55 siRNA-binding. {ECO:0000244|PDB:3VYY, ECO:0000269|PubMed:23361462}. 0.24 0.38 0.42 - - domain siRNA-binding. {ECO:0000244|PDB:3VYX, ECO:0000269|PubMed:23361462}. 182 186 siRNA-binding. {ECO:0000244|PDB:3VYX, ECO:0000269|PubMed:23361462}. 0.55 0.36 0.45 - - domain Interaction with BRCA1. {ECO:0000269|PubMed:9662397}. 230 325 Interaction with BRCA1. {ECO:0000269|PubMed:9662397}. 0.31 0.68 0.69 - - domain siRNA-binding. {ECO:0000305|PubMed:23361462}. 234 236 siRNA-binding. {ECO:0000305|PubMed:23361462}. 0.29 0.36 0.78 - - domain Necessary for interaction with RNA polymerase II holoenzyme. {ECO:0000269|PubMed:9323138}. 255 664 Necessary for interaction with RNA polymerase II holoenzyme. {ECO:0000269|PubMed:9323138}. 0.51 0.69 0.42 - - domain Necessary for interaction with H2AFX. {ECO:0000269|PubMed:15613478}. 313 952 Necessary for interaction with H2AFX. {ECO:0000269|PubMed:15613478}. 0.79 0.2 0.37 - - domain MTAD. {ECO:0000269|PubMed:11416126}. 331 380 MTAD. {ECO:0000269|PubMed:11416126}. 0.21 0.79 0.36 - - domain Core helicase. {ECO:0000305|PubMed:25062910}. 398 809 Core helicase. {ECO:0000305|PubMed:25062910}. 0.74 0.75 0.65 - - domain HA2. {ECO:0000269|PubMed:25062910}. 831 919 HA2. {ECO:0000269|PubMed:25062910}. 0.71 0.23 0.65 - - domain OB-fold. {ECO:0000269|PubMed:20696886, ECO:0000269|PubMed:25062910, ECO:0000269|PubMed:25149208}. 958 1074 OB-fold. {ECO:0000269|PubMed:20696886, ECO:0000269|PubMed:25062910, ECO:0000269|PubMed:25149208}. 0.42 0.5 0.23 - - domain RGG. {ECO:0000269|PubMed:10207077, ECO:0000269|PubMed:25062910, ECO:0000269|PubMed:25149208, ECO:0000269|PubMed:9111062}. 1150 1270 RGG. {ECO:0000269|PubMed:10207077, ECO:0000269|PubMed:25062910, ECO:0000269|PubMed:25149208, ECO:0000269|PubMed:9111062}. 0.75 0.5 0.3 - - domain DEIH box. 511 514 DEIH box. 0 0.75 0.85 - - domain Nuclear localization signal (NLS1). {ECO:0000255}. 586 595 Nuclear localization signal (NLS1). {ECO:0000255}. 0 0.96 0.64 - - domain Nuclear localization signal (NLS2). {ECO:0000269|PubMed:16375861}. 1155 1173 Nuclear localization signal (NLS2). {ECO:0000269|PubMed:16375861}. 0.31 0.2 0.2 - - mutation Missense_Mutation 54 54 p.K54E 1.0 1.0 0.0 circle up mutation Missense_Mutation 66 66 p.V66I 1.0 1.0 0.0 circle up mutation Missense_Mutation 149 149 p.Y149C 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 240 240 p.Q240* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 325 325 p.N325H 1.0 1.0 0.0 circle up mutation Missense_Mutation 328 328 p.G328C 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 474 474 p.R474* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 534 534 p.Y534F 1.0 1.0 0.0 circle up mutation Missense_Mutation 679 679 p.H679Y 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 767 767 p.R767* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 767 767 p.R767Q 1.0 1.0 0.0 circle up mutation Missense_Mutation 769 769 p.R769P 1.0 1.0 0.0 circle up mutation Missense_Mutation 812 812 p.G812E 1.0 1.0 0.0 circle up mutation Missense_Mutation 916 916 p.V916I 1.0 1.0 0.0 circle up mutation Missense_Mutation 993 993 p.S993C 1.0 1.0 0.0 circle up mutation Frame_Shift_Del 1065 1065 p.L1065Cfs*20 1.0 0.0 0.0 square up mutation Nonsense_Mutation 1166 1166 p.R1166* 1.0 0.0 0.0 triangle up mutation Nonsense_Mutation 1166 1166 p.R1166* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 1200 1200 p.G1200C 1.0 1.0 0.0 circle up