feature type start end label R G B shape direction protein Name=NOTCH1; Synonyms=TAN1; 1 2555 Name=NOTCH1; Synonyms=TAN1; 0.7 0.9 0.9 - - domain Neurogenic locus notch homolog protein 1. 19 2555 Neurogenic locus notch homolog protein 1. 0.28 0.33 0.4 - - domain Notch 1 extracellular truncation. {ECO:0000250}. 1721 2555 Notch 1 extracellular truncation. {ECO:0000250}. 0.53 0.65 0.21 - - domain Notch 1 intracellular domain. {ECO:0000250}. 1754 2555 Notch 1 intracellular domain. {ECO:0000250}. 0.62 0.24 0.46 - - domain Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 420 421 Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 0.46 0.73 0.72 - - domain Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 448 452 Interaction with DLL4. {ECO:0000250|UniProtKB:Q07008}. 0.46 0.73 0.72 - - domain HIF1AN-binding. {ECO:0000250}. 1947 1955 HIF1AN-binding. {ECO:0000250}. 0.76 0.7 0.47 - - domain HIF1AN-binding. {ECO:0000250}. 2014 2022 HIF1AN-binding. {ECO:0000250}. 0.76 0.7 0.47 - - mutation Silent 2535 2535 p.G2535G 0.8 0.8 0.8 circle up mutation Frame_Shift_Del 2486 2486 p.S2486Rfs*103 1.0 0.0 0.0 square up mutation Missense_Mutation 2354 2354 p.L2354H 1.0 1.0 0.0 circle up mutation Missense_Mutation 2346 2346 p.M2346T 1.0 1.0 0.0 circle up mutation Missense_Mutation 2301 2301 p.S2301F 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 2102 2102 p.Q2102* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 1929 1929 p.E1929K 1.0 1.0 0.0 circle up mutation Frame_Shift_Del 1916 1916 p.Q1916Rfs*65 1.0 0.0 0.0 square up mutation Silent 1791 1791 p.S1791S 0.8 0.8 0.8 circle up mutation Silent 1759 1759 p.K1759K 0.8 0.8 0.8 circle up mutation Frame_Shift_Del 1730 1730 p.P1730Rfs*68 1.0 0.0 0.0 square up mutation Nonsense_Mutation 1679 1679 p.E1679* 1.0 0.0 0.0 triangle up mutation Silent 1622 1622 p.R1622R 0.8 0.8 0.8 circle up mutation Missense_Mutation 1601 1601 p.H1601Q 1.0 1.0 0.0 circle up mutation Missense_Mutation 1546 1546 p.D1546Y 1.0 1.0 0.0 circle up mutation Missense_Mutation 1471 1471 p.A1471T 1.0 1.0 0.0 circle up mutation Missense_Mutation 1458 1458 p.A1458V 1.0 1.0 0.0 circle up mutation Silent 1359 1359 p.N1359N 0.8 0.8 0.8 circle up mutation Silent 1022 1022 p.V1022V 0.8 0.8 0.8 circle up mutation Missense_Mutation 974 974 p.G974R 1.0 1.0 0.0 circle up mutation Missense_Mutation 959 959 p.N959Y 1.0 1.0 0.0 circle up mutation In_Frame_Del 944 944 p.E944del 0.0 0.0 1.0 square up mutation Missense_Mutation 866 866 p.C866Y 1.0 1.0 0.0 circle up mutation Splice_Site 863 863 p.G863V 0.6 0.0 0.6 inv_triangle up mutation Missense_Mutation 745 745 p.W745C 1.0 1.0 0.0 circle up mutation Silent 720 720 p.C720C 0.8 0.8 0.8 circle up mutation Missense_Mutation 683 683 p.A683P 1.0 1.0 0.0 circle up mutation Missense_Mutation 520 520 p.F520I 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 439 439 p.Q439* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 377 377 p.I377M 1.0 1.0 0.0 circle up mutation Missense_Mutation 376 376 p.C376W 1.0 1.0 0.0 circle up mutation In_Frame_Del 357 357 p.F357del 0.0 0.0 1.0 square up mutation Frame_Shift_Del 324 324 p.V324fs 1.0 0.0 0.0 square up mutation Missense_Mutation 212 212 p.G212S 1.0 1.0 0.0 circle up mutation Missense_Mutation 144 144 p.C144Y 1.0 1.0 0.0 circle up