feature	type	start	end	label	R	G	B	shape	direction
protein	Name=PTEN; Synonyms=MMAC1, TEP1;	1	403	Name=PTEN; Synonyms=MMAC1, TEP1;	0.7	0.9	0.9	-	-
domain	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN.	2	403	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN.	0.66	0.74	0.64	-	-
domain	Required for interaction with NOP53. {ECO:0000269|PubMed:15355975}.	338	348	Required for interaction with NOP53. {ECO:0000269|PubMed:15355975}.	0.65	0.2	0.5	-	-
domain	PDZ domain-binding.	401	403	PDZ domain-binding.	0.29	0.3	0.43	-	-
mutation	Nonsense_Mutation	7	7	p.E7*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	7	7	p.E7*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	7	7	p.E7*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	12	12	p.N12Tfs*12	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	24	24	p.D24G	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	27	27	p.Y27*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	30	30	p.P30Yfs*11	1.0	0.0	0.0	square	up
mutation	In_Frame_Del	32	32	p.I32del	0.0	0.0	1.0	square	up
mutation	Missense_Mutation	33	33	p.I33V	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	38	38	p.P38S	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	43	43	p.E43*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	44	44	p.G44Qfs*3	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	47	47	p.R47Efs*4	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	51	51	p.D51*	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	56	56	p.F56C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	61	61	p.H61L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	68	68	p.Y68C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	69	69	p.N69T	1.0	1.0	0.0	circle	up
mutation	Splice_Site	70	70	p.X70_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Missense_Mutation	76	76	p.Y76F	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	78	78	p.T78S	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	87	87	p.Q87fs	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	88	88	p.Y88Sfs*3	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	88	88	p.Y88D	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	92	92	p.D92N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	92	92	p.D92N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	92	92	p.D92E	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	92	92	p.D92E	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	92	92	p.D92E	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	93	93	p.H93R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	93	93	p.H93R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	93	93	p.H93R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	96	96	p.P96S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	96	96	p.P96S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	96	96	p.P96T	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	97	97	p.Q97*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	98	98	p.L98fs	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	99	99	p.E99*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	99	99	p.E99*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	111	111	p.W111*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	111	111	p.W111*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Ins	118	118	p.H118Qfs*8	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	122	122	p.I122N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	122	122	p.I122N	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	123	123	p.H123R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	124	124	p.C124S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	125	125	p.K125E	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	126	126	p.A126T	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	126	126	p.A126S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	126	126	p.A126D	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	127	127	p.G127R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	127	127	p.G127V	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	129	129	p.G129R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	129	129	p.G129R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	129	129	p.G129E	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	130	130	p.R130G	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	130	130	p.R130*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	130	130	p.R130Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130Q	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130P	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	130	130	p.R130L	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	131	131	p.T131I	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Ins	134	134	p.M134Nfs*46	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	136	136	p.C136R	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	136	136	p.C136Y	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	139	139	p.L139V	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	140	140	p.L140Qfs*36	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	151	151	p.A151fs	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	155	155	p.Y155C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	159	159	p.R159S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	162	162	p.D162V	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Ins	166	166	p.V166Sfs*14	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	165	165	p.G165V	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Ins	168	168	p.I168Sfs*13	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	171	171	p.Q171*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	173	173	p.R173C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	173	173	p.R173C	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	173	173	p.R173H	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	173	173	p.R173H	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	174	174	p.Y174N	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	176	176	p.Y176*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	177	177	p.Y177C	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	180	180	p.Y180*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	206	206	p.F206L	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	209	209	p.G209*	1.0	0.0	0.0	triangle	up
mutation	Splice_Site	212	212	p.X212_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Splice_Site	212	212	p.X212_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Nonsense_Mutation	214	214	p.Q214*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	214	214	p.Q214*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	215	215	p.F215S	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	217	217	p.V217D	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	218	218	p.C218*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	229	229	p.S229*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	233	233	p.R233*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	233	233	p.R233*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	233	233	p.R233*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	233	233	p.R233*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	233	233	p.R233*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Ins	242	242	p.E242*	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	245	245	p.Q245*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	246	246	p.P246L	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Ins	248	248	p.P248Tfs*5	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	248	248	p.P248Tfs*5	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	251	251	p.G251D	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	253	253	p.I253Qfs*44	1.0	0.0	0.0	square	up
mutation	Missense_Mutation	252	252	p.D252G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	253	253	p.I253N	1.0	1.0	0.0	circle	up
mutation	Frame_Shift_Del	258	258	p.F258Sfs*8	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	262	262	p.N262Qfs*35	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	268	268	p.D268Gfs*30	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	268	268	p.D268Gfs*30	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	267	267	p.K267Rfs*9	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	267	267	p.K267Rfs*9	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	267	267	p.K267Rfs*9	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	266	266	p.K266*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	267	267	p.K267Rfs*30	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	274	274	p.W274*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	287	287	p.S287*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	290	290	p.V290*	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	293	293	p.G293Efs*14	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	293	293	p.G293Efs*14	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	293	293	p.G293*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Ins	295	295	p.L295Sfs*3	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	296	296	p.C296*	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	300	300	p.I300Mfs*7	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	304	304	p.C304*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Del	319	319	p.T319*	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	319	319	p.T319*	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	319	319	p.T319*	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	321	321	p.T321Kfs*22	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	323	323	p.N323Kfs*2	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Ins	323	323	p.N323Kfs*2	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	323	323	p.N323Mfs*21	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	323	323	p.N323Kfs*12	1.0	0.0	0.0	square	up
mutation	Frame_Shift_Del	329	329	p.N329Kfs*14	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	335	335	p.R335*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	341	341	p.F341V	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	341	341	p.F341V	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	341	341	p.F341C	1.0	1.0	0.0	circle	up
mutation	Splice_Site	343	343	p.X343_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Splice_Site	343	343	p.X343_splice	0.6	0.0	0.6	inv_triangle	up