feature	type	start	end	label	R	G	B	shape	direction
protein	Name=RB1;	1	928	Name=RB1;	0.7	0.9	0.9	-	-
domain	Retinoblastoma-associated protein.	2	928	Retinoblastoma-associated protein.	0.69	0.76	0.35	-	-
domain	Pocket; binds T and E1A.	373	771	Pocket; binds T and E1A.	0.51	0.37	0.6	-	-
domain	Domain A.	373	579	Domain A.	0.26	0.27	0.38	-	-
domain	Spacer.	580	639	Spacer.	0.56	0.46	0.25	-	-
domain	Domain B.	640	771	Domain B.	0.21	0.66	0.31	-	-
domain	Interaction with LIMD1. {ECO:0000269|PubMed:15542589}.	763	928	Interaction with LIMD1. {ECO:0000269|PubMed:15542589}.	0.26	0.5	0.78	-	-
domain	Domain C; mediates interaction with E4F1. {ECO:0000269|PubMed:10869426}.	771	928	Domain C; mediates interaction with E4F1. {ECO:0000269|PubMed:10869426}.	0.76	0.55	0.62	-	-
domain	Nuclear localization signal. {ECO:0000305}.	870	876	Nuclear localization signal. {ECO:0000305}.	0.5	0.65	0.53	-	-
mutation	Frame_Shift_Ins	7	7	p.R7Pfs*24	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	54	54	p.E54*	1.0	0.0	0.0	triangle	up
mutation	Frame_Shift_Ins	74	74	p.A74Efs*4	1.0	0.0	0.0	square	up
mutation	Nonsense_Mutation	137	137	p.E137*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	192	192	p.K192N	1.0	1.0	0.0	circle	up
mutation	Splice_Site	287	287	p.X287_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Splice_Site	288	288	p.X288_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Missense_Mutation	330	330	p.D330N	1.0	1.0	0.0	circle	up
mutation	Splice_Region	349	349	p.D349=	0.6	0.0	0.6	inv_triangle	up
mutation	Nonsense_Mutation	358	358	p.R358*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	358	358	p.R358*	1.0	0.0	0.0	triangle	up
mutation	Missense_Mutation	375	375	p.V375G	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	384	384	p.Q384H	1.0	1.0	0.0	circle	up
mutation	Missense_Mutation	400	400	p.L400R	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	443	443	p.S443*	1.0	0.0	0.0	triangle	up
mutation	Splice_Site	500	500	p.X500_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Splice_Site	500	500	p.X500_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Missense_Mutation	503	503	p.S503F	1.0	1.0	0.0	circle	up
mutation	In_Frame_Ins	515	515	p.515_516insWILNVLNL	0.0	0.0	1.0	square	up
mutation	Missense_Mutation	533	533	p.E533K	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	552	552	p.R552*	1.0	0.0	0.0	triangle	up
mutation	Splice_Site	565	565	p.X565_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Frame_Shift_Del	584	584	p.D584Tfs*26	1.0	0.0	0.0	square	up
mutation	Splice_Site	605	605	p.X605_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Splice_Site	654	654	p.X654_splice	0.6	0.0	0.6	inv_triangle	up
mutation	Missense_Mutation	759	759	p.V759G	1.0	1.0	0.0	circle	up
mutation	Nonsense_Mutation	762	762	p.Q762*	1.0	0.0	0.0	triangle	up
mutation	Silent	762	762	p.Q762Q	0.8	0.8	0.8	circle	up
mutation	Nonsense_Mutation	790	790	p.Y790*	1.0	0.0	0.0	triangle	up
mutation	Nonsense_Mutation	850	850	p.Q850*	1.0	0.0	0.0	triangle	up