feature type start end label R G B shape direction protein Name=STK11; Synonyms=LKB1, PJS; 1 433 Name=STK11; Synonyms=LKB1, PJS; 0.7 0.9 0.9 - - domain Serine/threonine-protein kinase STK11. 1 430 Serine/threonine-protein kinase STK11. 0.62 0.62 0.41 - - domain ATP. {ECO:0000255|PROSITE- ProRule:PRU00159}. 55 63 ATP. {ECO:0000255|PROSITE- ProRule:PRU00159}. 0.29 0.25 0.26 - - domain Sufficient for interaction with SIRT1. {ECO:0000269|PubMed:18687677}. 45 90 Sufficient for interaction with SIRT1. {ECO:0000269|PubMed:18687677}. 0.32 0.65 0.28 - - mutation Frame_Shift_Ins 52 52 p.G52Wfs*13 1.0 0.0 0.0 square up mutation Frame_Shift_Ins 57 57 p.E57Gfs*106 1.0 0.0 0.0 square up mutation Nonsense_Mutation 60 60 p.Y60* 1.0 0.0 0.0 triangle up mutation Silent 71 71 p.T71T 0.8 0.8 0.8 circle up mutation Frame_Shift_Ins 74 74 p.R74Mfs*91 1.0 0.0 0.0 square up mutation Nonsense_Mutation 123 123 p.Q123* 1.0 0.0 0.0 triangle up mutation Splice_Site 125 125 p.X125_splice 0.6 0.0 0.6 inv_triangle up mutation Splice_Site 125 125 p.X125_splice 0.6 0.0 0.6 inv_triangle up mutation Nonsense_Mutation 137 137 p.Q137* 1.0 0.0 0.0 triangle up mutation Nonsense_Mutation 145 145 p.E145* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 195 195 p.L195R 1.0 1.0 0.0 circle up mutation Missense_Mutation 196 196 p.G196R 1.0 1.0 0.0 circle up mutation Splice_Site 200 200 p.X200_splice 0.6 0.0 0.6 inv_triangle up mutation Missense_Mutation 237 237 p.D237V 1.0 1.0 0.0 circle up mutation Missense_Mutation 251 251 p.G251C 1.0 1.0 0.0 circle up mutation Nonsense_Mutation 265 265 p.E265* 1.0 0.0 0.0 triangle up mutation Missense_Mutation 304 304 p.R304W 1.0 1.0 0.0 circle up mutation Missense_Mutation 308 308 p.W308L 1.0 1.0 0.0 circle up mutation Missense_Mutation 308 308 p.W308C 1.0 1.0 0.0 circle up mutation Frame_Shift_Ins 330 330 p.D330Vfs*30 1.0 0.0 0.0 square up mutation Nonsense_Mutation 332 332 p.W332* 1.0 0.0 0.0 triangle up