| MutSigPreprocess1 individual_set_id | LUSC |
| MutSigPreprocess1 maf1 | dependentsValues2455538420391063611.tsv |
| MutSigPreprocess1 maflabel1 | Broad |
| MutSigPreprocess1 maflabel2 | WashU |
| MutSigPreprocess1 maflabel3 | Baylor |
| MutSigPreprocess1 wig1 | dependentsValues4391703845460544164.tsv |
| MutSigPreprocess1 build | hg18 |
| MutSigPreprocess1 context65_dir | /xchip/cga1/lawrence/db/context65 |
| MutSigPreprocess1 context65_wig | /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig |
| MutSigPreprocess1 num_categories | 4 |
| MutSigPreprocess1 target_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt |
| MutSigPreprocess1 paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 individual_set_id | LUSC |
| MutSigRun3 gene_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt |
| MutSigRun3 build | hg18 |
| MutSigRun3 geneset_file | /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt |
| MutSigRun3 cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| MutSigRun3 refseq_file | /xchip/cga1/annotation/db/ucsc/hg18/R.mat |
| MutSigRun3 genome_dir | /xchip/cga1/annotation/db/ucsc/hg18 |
| MutSigRun3 param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| MutSigRun3 jobcount | 200 |
| GDAC_MutSig_Report4 ind_set | LUSC |
| Execution Times: | |
| Submitted: | 05:18:26 14-04-12 |
| Completed: | |
| Elapsed: | 02 hrs 53 mins 08 secs |
step 1. MutSigPreprocess [id: 77862] preprocess patient list and mutations
urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:63
| individual_set_id | LUSC |
| maf1 | dependentsValues2455538420391063611.tsv |
| maf2 | |
| maf3 | |
| maf4 | |
| maflabel1 | Broad |
| maflabel2 | WashU |
| maflabel3 | Baylor |
| maflabel4 | |
| wig1 | dependentsValues4391703845460544164.tsv |
| wig2 | |
| wig3 | |
| wig4 | |
| build | hg18 |
| context65_dir | /xchip/cga1/lawrence/db/context65 |
| context65_wig | /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig |
| num_categories | 4 |
| target_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt |
| paramfile | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| Output Files: | |
| LUSC.mutation_preprocessing_report.txt | |
| LUSC.patients.txt | |
| LUSC.coverage.prepare.txt | |
| LUSC.maf | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 05:18:26 14-04-12 |
| Completed: | 05:49:45 14-04-12 |
| Elapsed: | 00 hrs 31 mins 19 secs |
step 2. ProcessCoverageForMutSig [id: 77863] processes coverage from wiggle files and does automatic category discovery
urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:50
| coverage_prepare_file | LUSC.coverage.prepare.txt |
| patient_list | LUSC.patients.txt |
| mutation_list | LUSC.maf |
| Execution Times: | |
| Submitted: | 05:18:26 14-04-12 |
| Completed: | 06:33:10 14-04-12 |
| Elapsed: | 01 hrs 14 mins 43 secs |
step 3. MutSigRun [id: 77864] perform MutSig calculations, generates output tables and report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:120
| individual_set_id | LUSC |
| mutation_file | LUSC.maf |
| coverage_file | LUSC.coverage.mat |
| patient_file | LUSC.patients.txt |
| category_file | LUSC.mutcategs.txt |
| gene_list | /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt |
| build | hg18 |
| geneset_file | /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt |
| cosmic_file | /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv |
| refseq_file | /xchip/cga1/annotation/db/ucsc/hg18/R.mat |
| genome_dir | /xchip/cga1/annotation/db/ucsc/hg18 |
| param_file | /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt |
| mutation_preprocessing_report_file | LUSC.mutation_preprocessing_report.txt |
| jobcount | 200 |
| Execution Times: | |
| Submitted: | 05:18:26 14-04-12 |
| Completed: | 08:11:17 14-04-12 |
| Elapsed: | 02 hrs 52 mins 51 secs |
step 4. GDAC_MutSig_Report [id: 77865] Somatic Mutation Report
urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:10
| bar_plot | LUSC.bargraphs.png |
| breakdown_table | LUSC.mutation_breakdown.txt |
| categories_table | LUSC.mutation_rates.txt |
| coverage png | LUSC.covplot.png |
| sig_table | LUSC.sig_genes.txt |
| cosmic_table | LUSC.cosmic_sig_genes.txt |
| cosmic_table2 | LUSC.cosmic_sig_genes2.txt |
| cosmic_muts_table | LUSC.cosmic_mutations.txt |
| cluster_table | LUSC.clustered_muts.txt |
| geneset_table | LUSC.sig_genesets.txt |
| genset_table2 | LUSC.sig_genesets_2.txt |
| patients_c_and_r | LUSC.patients.counts_and_rates.txt |
| ind_set | LUSC |
| mutsig_version | LUSC.MutSig_version.txt |
| Output Files: | |
| nozzle.RData | |
| nozzle.html | |
| .lsf.out | |
| stdout.txt | |
| Execution Times: | |
| Submitted: | 05:18:26 14-04-12 |
| Completed: | 08:11:32 14-04-12 |
| Elapsed: | 02 hrs 53 mins 06 secs |
