MutSigWithNozzleReport Execution Log 7:46 PM Sun May 27, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id PRAD
MutSigPreprocess1 maf1 dependentsValues2069416032532325041.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 dependentsValues6515102506872934929.tsv
MutSigPreprocess1 build hg18
MutSigPreprocess1 context65_dir /xchip/cga1/lawrence/db/context65
MutSigPreprocess1 context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 individual_set_id PRAD
MutSigRun3 gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
MutSigRun3 build hg18
MutSigRun3 geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg18
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
MutSigRun3 jobcount 200
GDAC_MutSig_Report4 ind_set PRAD
Execution Times:
Submitted: 19:46:27 27-05-12
Completed:
Elapsed: 05 hrs 17 mins 35 secs

step 1. MutSigPreprocess [id: 104363] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:63
individual_set_id PRAD
maf1 dependentsValues2069416032532325041.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 dependentsValues6515102506872934929.tsv
wig2
wig3
wig4
build hg18
context65_dir /xchip/cga1/lawrence/db/context65
context65_wig /xchip/cga1/lawrence/db/context65/RefSeq_exons_hg18_june2010_terr_only.wig
num_categories 4
target_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010_fix1.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
Output Files:
 PRAD.mutation_preprocessing_report.txt
 PRAD.maf
 PRAD.patients.txt
 PRAD.coverage.prepare.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 19:46:28 27-05-12
Completed: 23:40:40 27-05-12
Elapsed: 03 hrs 54 mins 12 secs

step 2. ProcessCoverageForMutSig [id: 104364] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:50
coverage_prepare_file PRAD.coverage.prepare.txt
patient_list PRAD.patients.txt
mutation_list PRAD.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 PRAD.covfiles
 PRAD.summed_coverage.fwi
 PRAD.summed_coverage.fwb
 PRAD.mutcateg_discovery.txt
 PRAD.mutcategs.txt
 PRAD.coverage.mat
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 19:46:28 27-05-12
Completed: 00:06:39 28-05-12
Elapsed: 04 hrs 20 mins 11 secs

step 3. MutSigRun [id: 104365] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:120
individual_set_id PRAD
mutation_file PRAD.maf
coverage_file PRAD.coverage.mat
patient_file PRAD.patients.txt
category_file PRAD.mutcategs.txt
gene_list /xchip/cga1/lawrence/capture/RefSeq_exons_hg18_june2010.genelist.txt
build hg18
geneset_file /xchip/tcga/gbm/analysis/lawrence/db/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg18/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg18
param_file /xchip/cga1/reference/mutsig_params/MutSig1.5.params.txt
mutation_preprocessing_report_file PRAD.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 PRAD.mutation_filtering_report.txt
 PRAD.MutSig_version.txt
 PRAD.per_exon.coverage.txt
 PRAD.covplot.png
 PRAD.patients.counts_and_rates.txt
 PRAD.covplot_hires.png
 PRAD.bargraphs.png
 PRAD.bargraphs_hires.png
 PRAD.num_patients.txt
 PRAD.final_analysis_set.maf
 PRAD.mutcategs.txt
 PRAD.per_gene.coverage.txt
 PRAD.mutation_breakdown.txt
 PRAD.per_gene.mutation_counts.txt
 PRAD.mutation_rates.txt
 PRAD.sample_sig_gene_table.txt
 PRAD.sig_genes.txt
 PRAD.sig_genesets.txt
 PRAD.sig_genesets_2.txt
 PRAD.cosmic_mutations.txt_verbose.txt
 PRAD.cosmic_sig_genes.txt
 PRAD.cosmic_sig_genes2.txt
 PRAD.cosmic_mutations.txt
 PRAD.clustered_muts.txt
 PRAD.gene_gene_correlations.txt
 PRAD.power_per_gene.total_coverage.txt
 PRAD.power_per_gene.total_coverage_histogram
 PRAD.power_per_gene.power_stats.txt
 PRAD.power_per_gene.power_stats_full.txt
 PRAD.power_per_gene.power_summary.txt
 PRAD.gene_coverage_plots
 sig_genes.txt
 patients.counts_and_rates.html
 SG_full.html
 GGC_full.html
 CSG_full.html
 CSG2_full.html
 CM_full.html
 CLM_full.html
 SGS_full.html
 SGS2_full.html
 report.html
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 19:46:28 27-05-12
Completed: 00:58:34 28-05-12
Elapsed: 05 hrs 12 mins 06 secs

step 4. GDAC_MutSig_Report [id: 104366] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:10
bar_plot PRAD.bargraphs.png
breakdown_table PRAD.mutation_breakdown.txt
categories_table PRAD.mutation_rates.txt
coverage png PRAD.covplot.png
sig_table PRAD.sig_genes.txt
cosmic_table PRAD.cosmic_sig_genes.txt
cosmic_table2 PRAD.cosmic_sig_genes2.txt
cosmic_muts_table PRAD.cosmic_mutations.txt
cluster_table PRAD.clustered_muts.txt
geneset_table PRAD.sig_genesets.txt
genset_table2 PRAD.sig_genesets_2.txt
patients_c_and_r PRAD.patients.counts_and_rates.txt
ind_set PRAD
mutsig_version PRAD.MutSig_version.txt
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 19:46:28 27-05-12
Completed: 01:04:00 28-05-12
Elapsed: 05 hrs 17 mins 32 secs