MutSigWithNozzleReport Execution Log 1:56 PM Sun Aug 5, '12

Running as user: cgaadm_deadline

MutSigPreprocess1 individual_set_id PRAD
MutSigPreprocess1 maf1 dependentsValues8665707765758208253.tsv
MutSigPreprocess1 maflabel1 Broad
MutSigPreprocess1 maflabel2 WashU
MutSigPreprocess1 maflabel3 Baylor
MutSigPreprocess1 wig1 dependentsValues7659201597281790844.tsv
MutSigPreprocess1 build hg19
MutSigPreprocess1 context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
MutSigPreprocess1 context65_wig no_longer_needed
MutSigPreprocess1 num_categories 4
MutSigPreprocess1 target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
MutSigPreprocess1 paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 individual_set_id PRAD
MutSigRun3 gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
MutSigRun3 build hg19
MutSigRun3 geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
MutSigRun3 cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
MutSigRun3 refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
MutSigRun3 genome_dir /xchip/cga1/annotation/db/ucsc/hg19
MutSigRun3 param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
MutSigRun3 jobcount 200
CoMut4 individualSetId PRAD
GDAC_MutSig_Report5 ind_set PRAD
Execution Times:
Submitted: 13:56:43 05-08-12
Completed:
Elapsed: 08 hrs 36 mins 27 secs

step 1. MutSigPreprocess [id: 142918] preprocess patient list and mutations

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00272:84
individual_set_id PRAD
maf1 dependentsValues8665707765758208253.tsv
maf2
maf3
maf4
maflabel1 Broad
maflabel2 WashU
maflabel3 Baylor
maflabel4
wig1 dependentsValues7659201597281790844.tsv
wig2
wig3
wig4
build hg19
context65_dir /xchip/cga1/annotation/db/tracks/hg19/c65e
context65_wig no_longer_needed
num_categories 4
target_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_hg19.txt
paramfile /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
Output Files:
 PRAD.mutation_preprocessing_report.txt
 PRAD.maf
 PRAD.coverage.prepare.txt
 PRAD.patients.txt
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:56:43 05-08-12
Completed: 14:12:22 05-08-12
Elapsed: 00 hrs 15 mins 38 secs

step 2. ProcessCoverageForMutSig [id: 142919] processes coverage from wiggle files and does automatic category discovery

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00188:72
coverage_prepare_file PRAD.coverage.prepare.txt
patient_list PRAD.patients.txt
mutation_list PRAD.maf
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 PRAD.summed_coverage.fwi
 PRAD.summed_coverage.fwb
 PRAD.mutcateg_discovery.txt
 PRAD.mutcategs.txt
 PRAD.coverage.mat
 PRAD.covfiles
 finished
 iterator.out.txt
 jobSubmissions.txt
 stdout.txt
Execution Times:
Submitted: 13:56:43 05-08-12
Completed: 15:23:42 05-08-12
Elapsed: 01 hrs 26 mins 58 secs

step 3. MutSigRun [id: 142920] perform MutSig calculations, generates output tables and report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00286:153
individual_set_id PRAD
mutation_file PRAD.maf
coverage_file PRAD.coverage.mat
patient_file PRAD.patients.txt
category_file PRAD.mutcategs.txt
gene_list /xchip/cga1/annotation/db/capture/Refseq_exons_good_20101221_genelist.txt
build hg19
geneset_file /xchip/cga1/annotation/db/genesets/gsea_canonical_pathway_plus_HMT67.txt
cosmic_file /xchip/cga1/annotation/db/cosmic/CosmicMutantExport_v48_260710_p25.tsv
refseq_file /xchip/cga1/annotation/db/ucsc/hg19/R.mat
genome_dir /xchip/cga1/annotation/db/ucsc/hg19
param_file /xchip/cga1/reference/mutsig_params/MutSig2.0.params.txt
mutation_preprocessing_report_file PRAD.mutation_preprocessing_report.txt
jobcount 200
Output Files:
 jobName.txt
 .lsf.out
 stderr.txt
 java.opts
 PRAD.mutation_filtering_report.txt
 PRAD.MutSig_version.txt
 PRAD.per_exon.coverage.txt
 PRAD.covplot.png
 PRAD.patients.counts_and_rates.txt
 PRAD.covplot_hires.png
 PRAD.bargraphs.png
 PRAD.bargraphs_hires.png
 PRAD.num_patients.txt
 PRAD.final_analysis_set.maf
 PRAD.mutcategs.txt
 PRAD.per_gene.coverage.txt
 PRAD.mutation_breakdown.txt
 PRAD.per_gene.mutation_counts.txt
 PRAD.mutsig2.images
 PRAD.mutation_rates.txt
 PRAD.sample_sig_gene_table.txt
 PRAD.sig_genes.txt
 PRAD.sig_genesets.txt
 PRAD.sig_genesets_2.txt
 PRAD.cosmic_mutations.txt_verbose.txt
 PRAD.cosmic_sig_genes.txt
 PRAD.cosmic_sig_genes2.txt
 PRAD.cosmic_mutations.txt
 PRAD.clustered_muts.txt
 PRAD.gene_gene_correlations.txt
 PRAD.power_per_gene.total_coverage.txt
 PRAD.power_per_gene.total_coverage_histogram
 PRAD.power_per_gene.power_stats.txt
 PRAD.power_per_gene.power_stats_full.txt
 PRAD.power_per_gene.power_summary.txt
 PRAD.gene_coverage_plots
 finished
 jobSubmissions.txt
 iterator.out.txt
 stdout.txt
Execution Times:
Submitted: 13:56:43 05-08-12
Completed: 22:32:23 05-08-12
Elapsed: 08 hrs 35 mins 40 secs

step 4. CoMut [id: 142921]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00488:4
individualSetId PRAD
patientCRFile PRAD.patients.counts_and_rates.txt
mafFile PRAD.final_analysis_set.maf
mutcategsFile PRAD.mutcategs.txt
sigGenesFile PRAD.sig_genes.txt
Output Files:
 PRAD_coMut.pdf
 PRAD_coMut.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:56:43 05-08-12
Completed: 22:32:48 05-08-12
Elapsed: 08 hrs 36 mins 04 secs

step 5. GDAC_MutSig_Report [id: 142922] Somatic Mutation Report

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00413:13
bar_plot PRAD.bargraphs.png
breakdown_table PRAD.mutation_breakdown.txt
categories_table PRAD.mutation_rates.txt
coverage png PRAD.covplot.png
sig_table PRAD.sig_genes.txt
cosmic_table PRAD.cosmic_sig_genes.txt
cosmic_table2 PRAD.cosmic_sig_genes2.txt
cosmic_muts_table PRAD.cosmic_mutations.txt
cluster_table PRAD.clustered_muts.txt
geneset_table PRAD.sig_genesets.txt
genset_table2 PRAD.sig_genesets_2.txt
patients_c_and_r PRAD.patients.counts_and_rates.txt
ind_set PRAD
mutsig_version PRAD.MutSig_version.txt
coMut_plot_png PRAD_coMut.png
coMut_plot_pdf PRAD_coMut.pdf
Output Files:
 nozzle.RData
 nozzle.html
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:56:43 05-08-12
Completed: 22:33:08 05-08-12
Elapsed: 08 hrs 36 mins 25 secs