Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.063 0.178 0.525 36.0 -9999.0 0.0 36.0 KIRREL -0.031 0.169 -9999.0 0.0 -0.744 16.0 16.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.055 0.182 -9999.0 0.0 -0.526 36.0 36.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.047 0.136 -9999.0 0.0 -0.51 16.0 16.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.008 0.106 -9999.0 0.0 -0.528 5.0 5.0 FYN -0.032 0.135 -9999.0 0.0 -0.468 18.0 18.0 mol:Ca2+ -0.047 0.134 -9999.0 0.0 -0.504 16.0 16.0 mol:DAG -0.047 0.135 -9999.0 0.0 -0.507 16.0 16.0 NPHS2 -0.006 0.022 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.047 0.135 -9999.0 0.0 -0.507 16.0 16.0 regulation of endocytosis -0.023 0.128 -9999.0 0.0 -0.451 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol -0.048 0.138 -9999.0 0.0 -0.4 36.0 36.0 establishment of cell polarity -0.063 0.178 -9999.0 0.0 -0.525 36.0 36.0 Nephrin/NEPH1/podocin/NCK1-2 -0.043 0.124 -9999.0 0.0 -0.666 5.0 5.0 Nephrin/NEPH1/beta Arrestin2 -0.022 0.13 -9999.0 0.0 -0.457 16.0 16.0 NPHS1 -0.045 0.166 -9999.0 0.0 -0.595 25.0 25.0 Nephrin/NEPH1/podocin -0.038 0.134 -9999.0 0.0 -0.471 18.0 18.0 TJP1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.047 0.136 -9999.0 0.0 -0.51 16.0 16.0 CD2AP 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.047 0.136 -9999.0 0.0 -0.51 16.0 16.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.031 0.138 -9999.0 0.0 -0.455 20.0 20.0 cytoskeleton organization -0.01 0.13 -9999.0 0.0 -0.515 11.0 11.0 Nephrin/NEPH1 -0.04 0.136 -9999.0 0.0 -0.387 36.0 36.0 Nephrin/NEPH1/ZO-1 -0.051 0.146 -9999.0 0.0 -0.545 16.0 16.0