Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.657 0.263 0.746 57.0 -9999.0 0.0 57.0 KIRREL -0.107 0.187 -9999.0 0.0 -0.945 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.659 0.264 -9999.0 0.0 -0.748 57.0 57.0 PLCG1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 -0.006 0.049 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.678 0.343 -9999.0 0.0 -0.747 59.0 59.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.515 0.283 -9999.0 0.0 -0.569 59.0 59.0 FYN -0.639 0.326 -9999.0 0.0 -0.705 59.0 59.0 mol:Ca2+ -0.666 0.332 -9999.0 0.0 -0.734 59.0 59.0 mol:DAG -0.672 0.338 -9999.0 0.0 -0.74 59.0 59.0 NPHS2 -0.406 0.43 -9999.0 0.0 -0.948 25.0 25.0 mol:IP3 -0.672 0.338 -9999.0 0.0 -0.74 59.0 59.0 regulation of endocytosis -0.607 0.303 -9999.0 0.0 -0.668 59.0 59.0 Nephrin/NEPH1/podocin/Cholesterol -0.683 0.344 -9999.0 0.0 -0.752 59.0 59.0 establishment of cell polarity -0.657 0.263 -9999.0 0.0 -0.746 57.0 57.0 Nephrin/NEPH1/podocin/NCK1-2 -0.633 0.328 -9999.0 0.0 -0.698 59.0 59.0 Nephrin/NEPH1/beta Arrestin2 -0.621 0.315 -9999.0 0.0 -0.683 59.0 59.0 NPHS1 -0.786 0.308 -9999.0 0.0 -0.908 56.0 56.0 Nephrin/NEPH1/podocin -0.647 0.33 -9999.0 0.0 -0.713 59.0 59.0 TJP1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.678 0.343 -9999.0 0.0 -0.747 59.0 59.0 CD2AP 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.678 0.343 -9999.0 0.0 -0.747 59.0 59.0 GRB2 0.008 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.633 0.327 -9999.0 0.0 -0.698 59.0 59.0 cytoskeleton organization -0.682 0.348 -9999.0 0.0 -0.753 59.0 59.0 Nephrin/NEPH1 -0.507 0.212 -9999.0 0.0 -0.576 57.0 57.0 Nephrin/NEPH1/ZO-1 -0.553 0.229 -9999.0 0.0 -0.628 57.0 57.0