Uterine Corpus Endometrioid Carcinoma: HotNet pathway analysis of mutation and copy number data
(primary solid tumor cohort)
(primary solid tumor cohort)
Maintained by Hailei Zhang
(Broad Institute)
Overview
Introduction
Summary
There were 102 significant subnetworks identified in HotNet analysis.
Results
Significant subnetworks
HotNet identifies 102 altered subnetworks based on the matched somatic mutation and copy number alterations data. Table 1 showes the top 10 significant subnetworks.
Network | No.ofgenes | p-value | RepeatTimes |
---|---|---|---|
PLXNA2(31),KIAA1199(18),DHX37(30) | 3 | 0 | 3 |
PTRF(26),NFATC3(28),TTF1(24) | 3 | 0 | 3 |
AHRR(39),ARNT2(17),ARNT(102) | 3 | 0 | 2 |
ALDOB(22),ATP6V1E1(27),ATP6V1G1(21) | 3 | 0 | 2 |
BOK(24),BMF(30),MCL1(101) | 3 | 0 | 2 |
CHRNA5(18),CHRNB4(18),CHRNA3(16) | 3 | 0 | 2 |
EPRS(26),IARS(24),DUS2L(26) | 3 | 0 | 2 |
ITM2C(25),STT3A(29),HJURP(27) | 3 | 0 | 2 |
PDIA3(30),SLC12A3(25),WNK4(29) | 3 | 0 | 2 |
PLXNB2(31),ARHGEF12(35),LPAR1(25) | 3 | 0 | 2 |
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
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