Molecular subtypes MRNA_CNMF MRNA_CHIERARCHICAL MIR_CNMF MIR_CHIERARCHICAL CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Chi-square test_P Chi-square test_Q Amp Peak 1(1p36.21) 89 (16%) 474 0.94102 1 0.23569 1 0.17861 1 0.007401 1 1.6333e-08 1.08e-05 0.44794 1 0.082138 1 0.052243 1 0.14244 1 0.4183 1 Amp Peak 2(1q32.1) 153 (27%) 410 0.72684 1 0.63768 1 0.23933 1 0.097026 1 1.7641e-08 1.17e-05 0.34979 1 0.87778 1 0.56297 1 0.18298 1 0.052376 1 Amp Peak 3(1q44) 96 (17%) 467 0.88331 1 0.5007 1 0.40262 1 0.44141 1 8.3221e-09 5.56e-06 0.59013 1 0.4044 1 0.12729 1 0.25279 1 0.00483 1 Amp Peak 4(2p24.3) 46 (8%) 517 0.004038 1 0.08243 1 0.74778 1 0.38452 1 0.00023794 0.138 0.028898 1 0.20809 1 0.43194 1 0.80074 1 4.3567e-06 0.00274 Amp Peak 5(3q26.33) 108 (19%) 455 0.051105 1 0.5584 1 0.90035 1 0.7237 1 3.5604e-06 0.00225 0.00029114 0.168 0.03943 1 0.0061397 1 0.10308 1 0.59484 1 Amp Peak 6(4p16.3) 46 (8%) 517 0.87634 1 0.60261 1 0.82766 1 0.4027 1 0.46549 1 0.16153 1 0.66204 1 0.13402 1 0.70426 1 0.46679 1 Amp Peak 7(4q12) 104 (18%) 459 0.00012711 0.0756 5.2378e-05 0.032 0.47905 1 0.052749 1 4.309e-07 0.000281 0.15652 1 0.29895 1 0.43662 1 0.012791 1 0.056936 1 Amp Peak 8(7p11.2) 494 (88%) 69 7.0174e-13 4.78e-10 1.6222e-10 1.1e-07 3.4793e-07 0.000228 2.3446e-13 1.6e-10 1.23e-20 8.56e-18 1.0352e-06 0.000664 9.2976e-06 0.00579 4.5228e-05 0.0277 5.3418e-05 0.0325 6.5753e-07 0.000424 Amp Peak 9(7q11.21) 452 (80%) 111 5.6825e-07 0.000368 1.8181e-05 0.0113 4.6898e-06 0.00295 7.422e-09 4.97e-06 1.7172e-09 1.15e-06 0.0032282 1 0.0045815 1 0.39561 1 0.0068015 1 0.0048377 1 Amp Peak 10(7q21.2) 468 (83%) 95 3.3403e-05 0.0205 0.00032133 0.185 0.010678 1 1.9215e-06 0.00122 1.06e-10 7.2e-08 0.0071632 1 0.019423 1 0.3314 1 0.080251 1 0.0033636 1 Amp Peak 11(7q31.2) 460 (82%) 103 0.00012865 0.0764 0.00049722 0.283 0.0020723 1 0.00014384 0.0852 2.2065e-07 0.000145 0.037816 1 0.11234 1 1 1 0.072202 1 0.0097972 1 Amp Peak 12(7q36.1) 465 (83%) 98 0.0010301 0.57 0.0033942 1 0.058961 1 4.5897e-05 0.028 1.4149e-05 0.00877 0.0071632 1 0.24197 1 0.65246 1 0.019286 1 0.00088796 0.494 Amp Peak 13(8q24.21) 64 (11%) 499 2.0093e-07 0.000132 0.00015657 0.0922 0.039655 1 8.3446e-05 0.0502 3.5071e-06 0.00222 0.062687 1 0.10018 1 0.083032 1 0.22692 1 5.5197e-05 0.0336 Amp Peak 14(11p13) 26 (5%) 537 0.41116 1 0.82691 1 0.32356 1 0.76882 1 0.45166 1 0.28509 1 0.24594 1 0.082222 1 0.52337 1 0.075739 1 Amp Peak 15(12p13.32) 81 (14%) 482 0.86726 1 0.64121 1 0.71588 1 0.8116 1 1.9604e-05 0.0121 0.23403 1 0.38059 1 0.59745 1 0.034324 1 0.75309 1 Amp Peak 16(12q14.1) 131 (23%) 432 0.084009 1 0.28276 1 0.30885 1 0.12133 1 1.7047e-09 1.15e-06 0.34721 1 0.042836 1 0.92784 1 0.023282 1 0.0062197 1 Amp Peak 17(12q15) 92 (16%) 471 0.74863 1 0.37677 1 0.75118 1 0.51534 1 2.8312e-07 0.000185 0.40426 1 0.24609 1 0.17813 1 0.11124 1 0.10563 1 Amp Peak 18(13q34) 30 (5%) 533 0.53564 1 0.75792 1 0.17 1 0.11474 1 0.013951 1 NA NA 0.056909 1 0.16355 1 0.9322 1 0.55113 1 Amp Peak 19(14q32.33) 34 (6%) 529 0.35039 1 0.47327 1 0.021052 1 0.94256 1 0.7935 1 1 1 0.037293 1 0.29994 1 0.26238 1 0.014016 1 Amp Peak 20(17p13.2) 45 (8%) 518 0.0023145 1 0.032718 1 0.075141 1 0.22116 1 0.0069571 1 0.52729 1 0.056836 1 0.19389 1 0.72649 1 0.10537 1 Amp Peak 21(17q25.1) 78 (14%) 485 0.060519 1 0.64557 1 0.40211 1 0.70871 1 5.9807e-05 0.0362 0.64297 1 0.14227 1 0.24371 1 0.4901 1 0.5604 1 Amp Peak 22(19p13.2) 240 (43%) 323 9.1223e-14 6.25e-11 8.1227e-09 5.43e-06 0.24827 1 0.0082518 1 1.8589e-20 1.29e-17 0.013413 1 0.0065172 1 0.00032659 0.187 0.0027437 1 0.010325 1 Amp Peak 23(19q12) 203 (36%) 360 1.2362e-09 8.32e-07 2.0983e-07 0.000138 0.21792 1 0.0044907 1 1.5008e-15 1.03e-12 0.10657 1 0.011702 1 0.005225 1 0.010145 1 0.00044483 0.254 Amp Peak 24(21q21.1) 67 (12%) 496 0.00044606 0.254 0.0077101 1 0.10796 1 0.079617 1 0.00077057 0.433 0.74817 1 0.69438 1 0.52078 1 0.025259 1 0.088891 1 Del Peak 1(1p36.32) 99 (18%) 464 0.21853 1 0.029283 1 0.5031 1 0.23348 1 0.61356 1 0.57683 1 0.49896 1 0.59989 1 0.23329 1 0.17194 1 Del Peak 2(1p36.23) 135 (24%) 428 0.040546 1 0.063934 1 0.36941 1 0.33027 1 0.0011817 0.648 0.49345 1 0.23955 1 0.9546 1 0.24246 1 0.1688 1 Del Peak 3(1p32.3) 60 (11%) 503 0.35939 1 0.43897 1 0.96958 1 0.87072 1 0.097256 1 0.68643 1 0.29465 1 0.68969 1 0.1545 1 0.31796 1 Del Peak 4(1p22.1) 47 (8%) 516 0.793 1 0.83917 1 0.76148 1 0.22798 1 0.17561 1 0.27123 1 0.7624 1 0.90441 1 0.095898 1 0.06371 1 Del Peak 5(1q42.11) 47 (8%) 516 0.77108 1 0.83569 1 0.40243 1 0.67875 1 0.6191 1 0.5282 1 0.18215 1 0.048686 1 0.6405 1 0.15337 1 Del Peak 6(1q44) 32 (6%) 531 0.60147 1 0.2904 1 0.68467 1 0.31498 1 0.61181 1 0.2919 1 0.79802 1 0.5141 1 0.60615 1 0.55212 1 Del Peak 7(2q22.1) 44 (8%) 519 0.028065 1 0.098038 1 0.43667 1 0.065113 1 1.6039e-06 0.00102 0.002189 1 0.47033 1 0.86922 1 0.27385 1 0.083153 1 Del Peak 8(2q37.1) 56 (10%) 507 0.015366 1 0.014728 1 0.23888 1 0.00096981 0.538 0.0068428 1 0.012237 1 0.67727 1 0.70128 1 0.16254 1 0.083153 1 Del Peak 9(3p21.1) 52 (9%) 511 0.066478 1 0.47017 1 0.91116 1 0.1043 1 0.00018654 0.109 0.27084 1 0.13015 1 0.82378 1 0.085343 1 0.022307 1 Del Peak 10(3q13.31) 55 (10%) 508 0.3672 1 0.77554 1 0.98007 1 0.70784 1 5.6848e-06 0.00356 0.20298 1 0.90192 1 0.85033 1 0.039999 1 0.0001803 0.105 Del Peak 11(3q22.1) 55 (10%) 508 0.45956 1 0.63909 1 0.61682 1 0.3777 1 0.00023454 0.136 0.37209 1 0.85836 1 0.76597 1 0.10843 1 0.0002559 0.148 Del Peak 12(3q29) 64 (11%) 499 0.11527 1 0.13685 1 0.61162 1 0.98373 1 0.0068314 1 0.13911 1 0.34482 1 0.55706 1 0.36795 1 0.57767 1 Del Peak 13(4p16.3) 78 (14%) 485 0.015761 1 0.035948 1 0.34963 1 0.17784 1 0.058245 1 1 1 0.82099 1 0.70057 1 0.90316 1 0.91556 1 Del Peak 14(4q34.3) 90 (16%) 473 0.00010123 0.0608 0.011968 1 0.088006 1 0.051942 1 0.00015259 0.0902 0.060983 1 0.085848 1 0.038486 1 0.63465 1 0.35355 1 Del Peak 15(5q35.3) 54 (10%) 509 1.9784e-05 0.0122 0.0021811 1 0.0015578 0.847 2.2734e-05 0.014 5.6874e-05 0.0345 0.011651 1 0.82904 1 0.28004 1 0.43601 1 0.1866 1 Del Peak 16(6q22.31) 153 (27%) 410 0.87323 1 0.63949 1 0.55412 1 0.029047 1 9.8261e-11 6.68e-08 0.1129 1 0.21048 1 0.12279 1 0.92696 1 0.41399 1 Del Peak 17(6q26) 173 (31%) 390 0.77495 1 0.24397 1 0.86611 1 0.12458 1 1.0804e-06 0.000691 0.7579 1 0.016615 1 0.017925 1 0.6332 1 0.28233 1 Del Peak 18(8p23.2) 67 (12%) 496 0.58115 1 0.13298 1 0.25599 1 0.35505 1 0.038237 1 0.89809 1 0.92889 1 0.8148 1 0.56947 1 0.57816 1 Del Peak 19(9p21.3) 408 (72%) 155 4.1856e-06 0.00264 7.9755e-07 0.000513 0.55421 1 0.0015261 0.832 3.77e-10 2.55e-07 0.011835 1 0.091677 1 0.040337 1 0.0077208 1 0.0023699 1 Del Peak 20(9q34.2) 71 (13%) 492 0.29155 1 0.061655 1 0.83957 1 0.40063 1 0.29163 1 0.8232 1 0.12275 1 0.083876 1 0.76246 1 0.24605 1 Del Peak 21(10p15.3) 457 (81%) 106 0.00012096 0.0722 2.847e-05 0.0175 0.013341 1 1.8478e-07 0.000122 1.4534e-14 9.97e-12 0.027238 1 0.0054922 1 0.025286 1 0.043724 1 0.0001028 0.0617 Del Peak 22(10p13) 459 (82%) 104 7.9461e-06 0.00496 2.1703e-06 0.00137 0.0028195 1 1.28e-07 8.46e-05 1.1124e-15 7.68e-13 0.027238 1 0.00013348 0.0792 0.0058353 1 0.16772 1 0.00079548 0.446 Del Peak 23(10p11.23) 463 (82%) 100 5.7848e-07 0.000374 1.97e-07 0.00013 0.0005396 0.306 1.2577e-08 8.38e-06 9.8539e-17 6.84e-14 0.03582 1 0.00080678 0.451 0.0016185 0.879 0.17048 1 0.00055652 0.315 Del Peak 24(10q23.31) 499 (89%) 64 6.5364e-05 0.0395 1.3387e-05 0.00831 0.007814 1 7.2286e-05 0.0437 1.1895e-16 8.24e-14 0.14247 1 0.010361 1 0.06089 1 0.38122 1 0.00063938 0.361 Del Peak 25(10q26.3) 500 (89%) 63 0.0001226 0.0731 6.4756e-06 0.00405 0.077666 1 0.00043043 0.246 1.8918e-13 1.29e-10 0.013491 1 0.12762 1 0.044861 1 0.64987 1 7.9912e-07 0.000513 Del Peak 26(11p15.5) 127 (23%) 436 7.7138e-10 5.2e-07 7.4077e-06 0.00463 0.22993 1 1.5029e-06 0.000959 2.0981e-15 1.44e-12 0.00011638 0.0696 0.28239 1 0.55424 1 0.0011032 0.608 0.0035396 1 Del Peak 27(11p11.2) 101 (18%) 462 4.4938e-07 0.000293 0.00099251 0.55 0.92055 1 2.4387e-05 0.015 2.1813e-13 1.49e-10 0.00087431 0.488 0.85673 1 0.67925 1 0.035635 1 0.11496 1 Del Peak 28(11q14.1) 95 (17%) 468 0.00030827 0.178 0.014871 1 0.93635 1 0.0078286 1 1.3012e-16 9e-14 0.23559 1 0.57052 1 0.58959 1 0.04517 1 0.13187 1 Del Peak 29(12p13.1) 75 (13%) 488 0.00015352 0.0906 0.0011282 0.619 0.12914 1 0.055956 1 0.077048 1 0.5945 1 0.84153 1 0.2712 1 0.83557 1 0.31829 1 Del Peak 30(12q12) 76 (13%) 487 0.00017816 0.104 0.0024229 1 0.18792 1 0.0064012 1 0.00017466 0.102 0.088888 1 0.13055 1 0.7477 1 0.16244 1 0.52908 1 Del Peak 31(12q15) 77 (14%) 486 0.00030733 0.177 0.00016274 0.0955 0.24664 1 0.046702 1 5.3978e-07 0.00035 0.2295 1 0.54885 1 0.84098 1 0.14705 1 0.39485 1 Del Peak 32(13q14.2) 236 (42%) 327 4.7635e-07 0.00031 1.6022e-06 0.00102 0.10858 1 0.080008 1 1.1047e-15 7.63e-13 0.030543 1 0.88338 1 0.028717 1 0.013066 1 0.00052326 0.297 Del Peak 33(14q13.1) 175 (31%) 388 7.1699e-07 0.000462 0.032877 1 0.618 1 0.42115 1 3.3563e-30 2.34e-27 0.10564 1 0.41863 1 0.29727 1 0.15361 1 0.35658 1 Del Peak 34(14q24.2) 170 (30%) 393 9.6566e-08 6.39e-05 0.0034891 1 0.065571 1 0.87103 1 7.6795e-39 5.36e-36 0.032748 1 0.45495 1 0.47092 1 0.012112 1 0.07808 1 Del Peak 35(14q31.3) 156 (28%) 407 1.3123e-08 8.73e-06 0.0019078 1 0.42159 1 0.8353 1 8.4204e-41 5.89e-38 0.0082937 1 0.53224 1 0.28867 1 0.058427 1 0.11349 1 Del Peak 36(15q14) 151 (27%) 412 8.6238e-09 5.75e-06 9.2921e-06 0.00579 0.0097737 1 1.3143e-06 0.00084 4.0889e-07 0.000267 0.00015874 0.0933 0.074824 1 0.0082756 1 0.0011053 0.608 0.00071179 0.401 Del Peak 37(16p12.2) 89 (16%) 474 0.30161 1 0.55774 1 0.06167 1 0.57751 1 0.094213 1 0.31033 1 0.45636 1 0.63966 1 0.26959 1 0.23163 1 Del Peak 38(16q23.3) 95 (17%) 468 0.15307 1 0.31328 1 0.75171 1 1 1 0.0044967 1 0.65087 1 0.046518 1 0.081594 1 0.26746 1 0.32243 1 Del Peak 39(17p13.2) 85 (15%) 478 0.20742 1 0.62887 1 0.9262 1 0.79959 1 2e-10 1.35e-07 0.27667 1 0.67324 1 0.41525 1 0.3558 1 0.048196 1 Del Peak 40(17p13.1) 95 (17%) 468 0.037084 1 0.1794 1 0.87993 1 0.60542 1 1.4187e-15 9.77e-13 0.1037 1 0.758 1 0.27253 1 0.1799 1 0.10182 1 Del Peak 41(17q11.2) 71 (13%) 492 7.3902e-05 0.0446 0.00072375 0.407 0.0019169 1 0.0095928 1 5.3222e-07 0.000345 0.6443 1 0.0071615 1 0.046703 1 0.033413 1 0.00087653 0.488 Del Peak 42(18q22.3) 79 (14%) 484 0.057195 1 0.32303 1 0.49848 1 0.4205 1 0.0020303 1 0.016903 1 0.030424 1 0.11546 1 0.058245 1 0.06093 1 Del Peak 43(19q13.41) 99 (18%) 464 1.9911e-06 0.00126 0.00019098 0.111 0.0017986 0.975 0.0010812 0.597 0.0012043 0.659 0.61857 1 0.033398 1 0.16674 1 0.015078 1 0.084941 1 Del Peak 44(21q22.3) 59 (10%) 504 0.0014835 0.81 0.018353 1 0.00010776 0.0646 0.0023862 1 0.14038 1 0.14459 1 0.36026 1 0.1438 1 0.10335 1 0.48091 1 Del Peak 45(22q13.32) 208 (37%) 355 0.70537 1 0.4324 1 0.019396 1 0.087987 1 0.00080426 0.45 0.75192 1 0.86427 1 0.37337 1 0.13442 1 0.027044 1 Del Peak 46(Xp22.2) 123 (22%) 440 0.00034646 0.199 0.022386 1 0.15546 1 0.20925 1 6.6031e-10 4.46e-07 0.0075275 1 0.57521 1 0.55209 1 0.73691 1 0.82906 1