Lung Squamous Cell Carcinoma: PARADIGM pathway analysis of mRNA expression and copy number data
(primary solid tumor cohort)
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
- Overview
+ Introduction
- Summary

There were 48 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
TCGA08_retinoblastoma 27
HIF-1-alpha transcription factor network 24
IL23-mediated signaling events 22
IL4-mediated signaling events 20
Signaling mediated by p38-alpha and p38-beta 20
Osteopontin-mediated events 19
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 19
Noncanonical Wnt signaling pathway 18
Fc-epsilon receptor I signaling in mast cells 18
Glucocorticoid receptor regulatory network 18
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data