Clinical Features	Time to Death		AGE		GENDER		DISTANT.METASTASIS		LYMPH.NODE.METASTASIS		TUMOR.STAGECODE		NEOPLASM.DISEASESTAGE	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Chi-square test_P	Chi-square test_Q	t-test_P	t-test_Q	Chi-square test_P	Chi-square test_Q
TP53	25 (17%)	121	0.4886	1	0.081574	1	1	1	0.6514	1	0.29498	1	NA	NA	0.31533	1
BRAF	73 (50%)	73	0.19479	1	0.047207	1	1	1	0.38882	1	0.6843	1	NA	NA	0.85242	1
C15ORF23	10 (7%)	136	0.45209	1	0.67243	1	0.74061	1	0.97655	1	0.68993	1	NA	NA	0.42619	1
CDKN2A	22 (15%)	124	0.71283	1	0.65382	1	1	1	0.89795	1	0.47355	1	NA	NA	0.72898	1
NRAS	45 (31%)	101	0.73038	1	0.1963	1	0.85654	1	0.57507	1	0.92848	1	NA	NA	0.29067	1
OXA1L	4 (3%)	142	0.88462	1	0.79277	1	0.64362	1	0.99534	1	0.73782	1	NA	NA	0.50131	1
STK19	9 (6%)	137	0.33187	1	0.51643	1	0.31268	1	0.98144	1	0.85421	1	NA	NA	0.91264	1
PTEN	11 (8%)	135	0.99883	1	0.60079	1	0.33996	1	0.0001797	0.133	0.72047	1	NA	NA	0.018472	1
RAC1	11 (8%)	135	0.048031	1	0.49655	1	1	1	0.97655	1	0.91603	1	NA	NA	0.38434	1
ACSM2B	28 (19%)	118	0.16443	1	0.96841	1	0.0025074	1	0.82705	1	0.57432	1	NA	NA	0.66479	1
CADM2	16 (11%)	130	0.7171	1	0.73552	1	1	1	0.92701	1	0.35789	1	NA	NA	0.33733	1
OR51S1	16 (11%)	130	0.44538	1	0.49469	1	1	1	0.94384	1	0.46529	1	NA	NA	0.1604	1
LCE1B	10 (7%)	136	0.39227	1	0.68414	1	0.51278	1	0.97655	1	0.35142	1	NA	NA	0.63729	1
IDH1	7 (5%)	139	0.79858	1	0.010376	1	0.4321	1	0.98577	1	0.92264	1	NA	NA	0.54359	1
TAF1A	8 (5%)	138	0.29057	1	0.62183	1	0.71169	1	0.0035526	1	0.9321	1	NA	NA	0.86408	1
NAP1L2	14 (10%)	132	0.36233	1	0.076989	1	0.3999	1	0.95146	1	0.60383	1	NA	NA	0.44714	1
MUC7	11 (8%)	135	0.46626	1	0.00018466	0.136	0.52884	1	0.9651	1	0.79452	1	NA	NA	0.66789	1
PPP6C	14 (10%)	132	0.032674	1	0.57843	1	1	1	0.40407	1	0.13502	1	NA	NA	0.47393	1
FRG2B	10 (7%)	136	0.52488	1	0.020493	1	0.51278	1	0.9711	1	0.85198	1	NA	NA	0.59886	1
USP29	25 (17%)	121	0.052734	1	0.075101	1	0.26367	1	0.87614	1	0.67698	1	NA	NA	0.41178	1
PRB4	16 (11%)	130	0.12471	1	0.23354	1	0.28353	1	0.44864	1	0.75893	1	NA	NA	0.90748	1
HIST1H2AA	7 (5%)	139	0.8797	1	0.96081	1	1	1	0.98577	1	0.93186	1	NA	NA	0.71832	1
RPTN	23 (16%)	123	0.63889	1	0.33722	1	0.8165	1	0.89795	1	0.48166	1	NA	NA	0.17103	1
ZNF479	13 (9%)	133	0.30696	1	0.17462	1	0.56902	1	0.35537	1	0.69213	1	NA	NA	0.7824	1
C8A	19 (13%)	127	0.047679	1	0.029101	1	0.12894	1	0.063657	1	0.74713	1	NA	NA	0.5757	1
FUT9	16 (11%)	130	0.98604	1	0.024076	1	1	1	0.93568	1	0.76	1	NA	NA	0.5891	1
ZNF679	15 (10%)	131	0.69571	1	0.41198	1	0.78253	1	0.94384	1	0.71324	1	NA	NA	0.48674	1
NRK	18 (12%)	128	0.36428	1	0.74056	1	0.79712	1	0.92701	1	0.70886	1	NA	NA	0.62234	1
CDH9	26 (18%)	120	0.43091	1	0.42665	1	1	1	0.82705	1	0.43436	1	NA	NA	0.072348	1
PRAMEF11	13 (9%)	133	0.10812	1	0.14349	1	0.56902	1	0.95855	1	0.2382	1	NA	NA	0.73832	1
DDX3X	15 (10%)	131	0.58405	1	0.41609	1	0.16239	1	0.00044074	0.324	0.93926	1	NA	NA	0.74358	1
GRXCR1	15 (10%)	131	0.59181	1	0.018565	1	0.78253	1	0.95146	1	0.79516	1	NA	NA	0.32502	1
PRB2	21 (14%)	125	0.57605	1	0.010714	1	0.053219	1	0.90813	1	0.65877	1	NA	NA	0.33524	1
ELF5	4 (3%)	142	0.42239	1	0.52341	1	1	1	0.99737	1	0.25509	1	NA	NA	0.95005	1
IL32	6 (4%)	140	0.067377	1	0.4639	1	0.67855	1	0.98953	1	0.86766	1	NA	NA	0.0053288	1
LUZP2	13 (9%)	133	0.88682	1	0.88955	1	0.56902	1	0.9651	1	0.73626	1	NA	NA	0.014877	1
PDE1A	23 (16%)	123	0.32551	1	0.13929	1	0.8165	1	0.88728	1	0.21213	1	NA	NA	0.52267	1
RBM11	10 (7%)	136	0.66862	1	0.26222	1	0.74061	1	0.24794	1	0.7314	1	NA	NA	0.56682	1
GLRB	16 (11%)	130	0.33878	1	0.10625	1	1	1	0.93568	1	0.75451	1	NA	NA	0.73459	1
PRB1	12 (8%)	134	0.36674	1	0.51811	1	0.12737	1	0.9711	1	0.51713	1	NA	NA	0.39743	1
KIAA1257	7 (5%)	139	0.093381	1	0.026572	1	0.24708	1	0.99534	1	0.67562	1	NA	NA	0.98161	1
USP17L2	13 (9%)	133	0.6677	1	0.99094	1	0.25085	1	0.95855	1	0.86044	1	NA	NA	0.2388	1
SPAG16	13 (9%)	133	0.15118	1	0.53173	1	0.25085	1	0.9651	1	0.81395	1	NA	NA	0.64248	1
OR4M2	17 (12%)	129	0.85124	1	0.079461	1	1	1	0.52506	1	0.96478	1	NA	NA	0.31635	1
GFRAL	20 (14%)	126	0.50568	1	0.594	1	0.80734	1	0.92701	1	0.48111	1	NA	NA	0.5387	1
UNC119B	3 (2%)	143	0.87331	1	0.37905	1	1	1	0.99737	1	0.98406	1	NA	NA	0.63756	1
PHGDH	5 (3%)	141	0.69982	1	0.99091	1	0.15673	1	0.99737	1	0.98406	1	NA	NA	NA	NA
STXBP5L	31 (21%)	115	0.10198	1	0.62988	1	0.68403	1	0.81371	1	0.96291	1	NA	NA	0.43465	1
TRAT1	10 (7%)	136	0.015337	1	0.66714	1	0.51278	1	0.97655	1	0.74149	1	NA	NA	0.79276	1
ZNF844	4 (3%)	142	0.4152	1	0.019116	1	0.64362	1	0.99534	1	0.46477	1	NA	NA	0.79995	1
TTN	114 (78%)	32	0.56617	1	0.79768	1	0.069483	1	0.22533	1	0.1555	1	NA	NA	0.14482	1
DSG3	34 (23%)	112	0.56485	1	0.11039	1	0.4251	1	0.24425	1	0.64179	1	NA	NA	0.37604	1
GML	8 (5%)	138	0.96743	1	0.10775	1	0.14971	1	0.98577	1	0.54261	1	NA	NA	0.94404	1
HHLA2	9 (6%)	137	0.67159	1	0.3116	1	1	1	0.98144	1	0.20589	1	NA	NA	0.81845	1
LILRB4	22 (15%)	124	0.41906	1	0.45618	1	0.81776	1	0.18795	1	0.68568	1	NA	NA	0.24609	1
SLC38A4	16 (11%)	130	0.74768	1	0.31199	1	0.10417	1	0.94384	1	0.87413	1	NA	NA	0.95483	1
OR2L3	12 (8%)	134	0.22041	1	0.72537	1	1	1	0.0077585	1	0.83407	1	NA	NA	0.39357	1
HBD	8 (5%)	138	0.090105	1	0.60404	1	0.71169	1	0.98144	1	0.81741	1	NA	NA	0.27289	1
TBC1D3B	3 (2%)	143	0.0028326	1	0.39778	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
TCEB3C	22 (15%)	124	0.39459	1	0.21771	1	0.1018	1	0.87614	1	0.41825	1	NA	NA	0.41143	1
CYLC2	16 (11%)	130	0.59993	1	0.08864	1	0.594	1	0.95146	1	0.042722	1	NA	NA	0.45424	1
HBG2	6 (4%)	140	0.61916	1	0.23873	1	1	1	0.98953	1	0.95276	1	NA	NA	0.76235	1
LOC649330	16 (11%)	130	0.31208	1	0.019545	1	0.594	1	0.95146	1	0.78847	1	NA	NA	0.79327	1
PARM1	11 (8%)	135	0.0094477	1	0.19704	1	1	1	0.97655	1	0.022293	1	NA	NA	0.25299	1
CCK	5 (3%)	141	0.1242	1	0.70594	1	0.64864	1	0.99534	1	0.0056554	1	NA	NA	0.54513	1
ZFP106	5 (3%)	141	0.80845	1	0.0042405	1	0.15673	1	0.99272	1	0.64722	1	NA	NA	0.20683	1
UGT2B15	14 (10%)	132	0.56809	1	0.64442	1	0.24876	1	0.35537	1	0.80971	1	NA	NA	0.15605	1
DSG1	22 (15%)	124	0.13564	1	0.49981	1	1	1	0.88728	1	0.81082	1	NA	NA	0.27341	1
ARL16	4 (3%)	142	0.33754	1	0.079686	1	1	1	0.99534	1	0.73782	1	NA	NA	0.29653	1
VEGFC	14 (10%)	132	0.93767	1	0.81056	1	0.3999	1	0.95855	1	0.046669	1	NA	NA	0.098871	1
PSG4	15 (10%)	131	0.94089	1	0.40902	1	1	1	0.95146	1	0.92113	1	NA	NA	0.80825	1
DEFB119	6 (4%)	140	0.059106	1	0.41638	1	1	1	0.99534	1	0.90823	1	NA	NA	0.82519	1
KLHL4	14 (10%)	132	0.13799	1	0.72734	1	0.3999	1	0.9651	1	0.78495	1	NA	NA	0.65714	1
EIF3D	3 (2%)	143	0.038014	1	0.47357	1	0.28111	1	0.99737	1	0.89084	1	NA	NA	0.57814	1
OR2W1	12 (8%)	134	0.70019	1	0.068732	1	0.53895	1	0.9651	1	0.22366	1	NA	NA	0.86047	1
OR4N2	17 (12%)	129	0.85613	1	0.33564	1	0.016267	1	0.063657	1	0.93665	1	NA	NA	0.74881	1
CCDC11	13 (9%)	133	0.76297	1	0.90887	1	1	1	0.95855	1	0.96962	1	NA	NA	0.83492	1
LIN7A	8 (5%)	138	0.43743	1	0.70313	1	0.48275	1	0.98953	1	0.93039	1	NA	NA	0.56654	1
RAPGEF5	6 (4%)	140	0.95659	1	0.46555	1	0.40444	1	0.99534	1	0.73782	1	NA	NA	0.85782	1
CD2	14 (10%)	132	0.56414	1	0.32279	1	0.77919	1	0.010965	1	0.83779	1	NA	NA	0.39687	1
C2ORF40	4 (3%)	142	0.74849	1	0.39245	1	0.64362	1	0.99737	1	0.94279	1	NA	NA	NA	NA
SGCZ	16 (11%)	130	0.11013	1	0.96506	1	1	1	0.9711	1	0.2653	1	NA	NA	0.8589	1
SPANXN2	13 (9%)	133	0.011485	1	0.7943	1	0.76692	1	0.9711	1	0.20503	1	NA	NA	0.39359	1
TLL1	31 (21%)	115	0.2817	1	0.20453	1	0.41489	1	0.72862	1	0.34014	1	NA	NA	0.20477	1
C9ORF119	5 (3%)	141	0.9235	1	0.96769	1	0.15673	1	0.99272	1	0.034834	1	NA	NA	0.70636	1
CCDC54	10 (7%)	136	0.45216	1	0.65298	1	0.31638	1	0.98144	1	0.965	1	NA	NA	0.82004	1
DEFB118	6 (4%)	140	0.13493	1	0.46171	1	1	1	0.98953	1	0.96506	1	NA	NA	0.63369	1
HTR3B	10 (7%)	136	0.03135	1	0.74478	1	0.31638	1	0.97655	1	0.87809	1	NA	NA	0.69276	1
MARCH11	7 (5%)	139	0.32138	1	0.99742	1	0.70533	1	0.087478	1	0.93186	1	NA	NA	0.46918	1
MKX	10 (7%)	136	0.46911	1	0.79769	1	0.74061	1	0.98577	1	0.93186	1	NA	NA	0.013284	1
OR5H2	11 (8%)	135	0.40633	1	0.027053	1	0.75123	1	0.9651	1	0.31775	1	NA	NA	0.42261	1
SIGLEC14	6 (4%)	140	0.89793	1	0.15374	1	0.08167	1	0.99272	1	0.94502	1	NA	NA	0.15297	1
TUBB8	7 (5%)	139	0.88123	1	0.22013	1	0.70533	1	0.99272	1	0.96392	1	NA	NA	0.69631	1
ZIM3	12 (8%)	134	0.043949	1	0.91602	1	0.36763	1	0.9711	1	0.62565	1	NA	NA	0.52131	1
PRC1	7 (5%)	139	0.98221	1	0.90706	1	0.70533	1	0.98953	1	0.91295	1	NA	NA	0.84204	1
MUM1L1	15 (10%)	131	0.48456	1	0.77509	1	1	1	0.93568	1	0.54667	1	NA	NA	0.68101	1
TRIM58	12 (8%)	134	0.39069	1	0.002222	1	0.76561	1	0.9651	1	0.73888	1	NA	NA	0.8259	1
ANKRD20A4	3 (2%)	143	0.57083	1	0.8649	1	0.28111	1	0.99737	1	0.94279	1	NA	NA	0.62319	1
OR5J2	10 (7%)	136	0.79474	1	0.8862	1	0.18901	1	0.98144	1	0.9558	1	NA	NA	0.79532	1
CLEC14A	14 (10%)	132	0.24538	1	0.83804	1	0.24876	1	0.9711	1	0.50996	1	NA	NA	0.61708	1
FAM19A1	7 (5%)	139	0.35394	1	0.95019	1	1	1	0.98953	1	0.59987	1	NA	NA	0.75068	1
GK2	19 (13%)	127	0.39008	1	0.98409	1	0.80426	1	0.91782	1	0.50348	1	NA	NA	0.064511	1
LONRF2	11 (8%)	135	0.035006	1	0.90859	1	1	1	0.98577	1	0.19078	1	NA	NA	0.67292	1
HAPLN1	7 (5%)	139	0.25893	1	0.17795	1	0.70533	1	0.00031604	0.233	0.93039	1	NA	NA	0.19581	1
NAP1L4	5 (3%)	141	0.61313	1	0.36917	1	0.37885	1	0.99272	1	0.26964	1	NA	NA	0.69273	1
CLCC1	7 (5%)	139	0.12232	1	0.57653	1	0.70533	1	0.98953	1	0.45669	1	NA	NA	0.73963	1
OR52J3	9 (6%)	137	0.069949	1	0.41732	1	0.73676	1	0.98144	1	0.92286	1	NA	NA	0.9347	1
TMCO5A	6 (4%)	140	0.38364	1	0.28992	1	0.40444	1	0.99272	1	0.96392	1	NA	NA	0.27315	1
C4ORF22	8 (5%)	138	0.29398	1	0.65368	1	0.48275	1	0.98953	1	0.93488	1	NA	NA	0.86828	1
MAP2K1	6 (4%)	140	0.19832	1	0.63598	1	0.20927	1	0.98953	1	0.0058502	1	NA	NA	0.91499	1
OR7D2	13 (9%)	133	0.9483	1	0.47945	1	0.25085	1	0.95855	1	0.86044	1	NA	NA	0.27355	1
CXCR2	9 (6%)	137	0.18068	1	0.34118	1	0.73676	1	0.98144	1	0.84127	1	NA	NA	0.27161	1
RBM22	4 (3%)	142	0.57865	1	0.31901	1	0.15617	1	0.99534	1	0.96435	1	NA	NA	0.78386	1
CX3CL1	3 (2%)	143	0.49541	1	0.94579	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
IGF2BP3	3 (2%)	143	0.91812	1	0.67791	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
KLRC3	4 (3%)	142	0.53244	1	0.69209	1	0.64362	1	0.99534	1	0.16909	1	NA	NA	0.828	1
LRRIQ4	14 (10%)	132	0.4297	1	0.1352	1	0.3999	1	0.94384	1	0.89848	1	NA	NA	0.62755	1
NR1H4	8 (5%)	138	0.36167	1	0.31501	1	0.48275	1	0.98577	1	0.19478	1	NA	NA	0.51305	1
OR4A15	14 (10%)	132	0.97502	1	0.041628	1	0.080432	1	0.9651	1	0.13406	1	NA	NA	0.36996	1
MAGEA4	7 (5%)	139	0.81886	1	0.56981	1	0.70533	1	0.046816	1	0.85323	1	NA	NA	0.64193	1
DGAT2L6	8 (5%)	138	0.48737	1	0.43669	1	1	1	0.98144	1	0.40517	1	NA	NA	0.55958	1
RGS18	7 (5%)	139	0.94375	1	0.32845	1	0.042831	1	0.98953	1	0.85323	1	NA	NA	0.76302	1
TSGA13	6 (4%)	140	0.29973	1	0.87271	1	0.40444	1	0.99272	1	0.92057	1	NA	NA	0.30808	1
OPN5	5 (3%)	141	0.32851	1	0.65632	1	0.64864	1	0.99534	1	0.84699	1	NA	NA	0.75391	1
SPINK13	4 (3%)	142	0.19134	1	0.32608	1	1	1	0.99534	1	0.35921	1	NA	NA	0.95606	1