Molecular subtypes CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nCNV (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q 1p gain 28 (11%) 216 0.009294 1 0.26523 1 0.14788 1 0.51716 1 0.081128 1 0.65624 1 0.96476 1 0.24881 1 1q gain 77 (32%) 167 7.1457e-09 4.4e-06 0.008452 1 0.36626 1 0.17243 1 0.07992 1 0.38509 1 0.19992 1 0.071675 1 2p gain 30 (12%) 214 0.0032081 1 0.30673 1 0.069563 1 0.39109 1 0.016512 1 0.030339 1 0.17319 1 0.017055 1 2q gain 28 (11%) 216 0.0024594 1 0.47482 1 0.01976 1 0.3842 1 0.0049157 1 0.0056436 1 0.022703 1 0.0057395 1 3p gain 23 (9%) 221 0.057977 1 0.067723 1 1 1 0.77075 1 0.24156 1 0.081495 1 0.47532 1 0.32495 1 3q gain 30 (12%) 214 0.15788 1 0.16407 1 0.56458 1 0.59406 1 0.17985 1 0.23223 1 0.90268 1 0.48199 1 4p gain 24 (10%) 220 0.001778 1 0.052276 1 0.97929 1 0.46856 1 0.81574 1 0.76897 1 0.77787 1 0.84797 1 4q gain 20 (8%) 224 0.0010149 0.587 0.035712 1 0.92289 1 0.9449 1 0.42655 1 0.53835 1 0.32754 1 0.88126 1 5p gain 28 (11%) 216 0.0096612 1 0.26523 1 0.75834 1 0.81906 1 0.90643 1 0.80627 1 0.13454 1 0.74811 1 5q gain 14 (6%) 230 0.021312 1 0.38881 1 0.62874 1 0.40445 1 0.3993 1 0.63396 1 0.18898 1 0.31932 1 6p gain 76 (31%) 168 2.2085e-10 1.37e-07 1.8746e-05 0.0113 0.089368 1 0.58862 1 0.26659 1 0.045788 1 0.01007 1 0.00081013 0.471 6q gain 18 (7%) 226 0.25042 1 0.056384 1 1 1 0.4979 1 0.66122 1 0.36691 1 0.76179 1 0.5572 1 7p gain 101 (41%) 143 3.047e-10 1.89e-07 0.10904 1 0.1947 1 0.29812 1 0.00048535 0.285 0.05916 1 0.83089 1 0.46126 1 7q gain 104 (43%) 140 6.5174e-12 4.05e-09 0.23604 1 0.13043 1 0.16729 1 0.00022244 0.133 0.044882 1 0.3064 1 0.10847 1 8p gain 49 (20%) 195 1.1591e-09 7.16e-07 0.011834 1 0.056231 1 0.36356 1 0.0084639 1 0.030795 1 0.70739 1 0.42515 1 8q gain 78 (32%) 166 1.6004e-09 9.87e-07 2.0133e-05 0.0121 0.60323 1 0.92449 1 0.00033537 0.199 0.0074954 1 0.55811 1 0.5814 1 9p gain 9 (4%) 235 0.76134 1 0.14419 1 0.11973 1 0.4352 1 0.39508 1 0.89388 1 0.55492 1 0.51219 1 9q gain 10 (4%) 234 0.098271 1 0.46761 1 0.23617 1 0.59993 1 0.39385 1 0.82347 1 0.55492 1 0.51219 1 11p gain 17 (7%) 227 0.0098626 1 0.90146 1 0.14706 1 0.47436 1 0.023079 1 0.047658 1 0.37076 1 0.096301 1 11q gain 15 (6%) 229 0.00031444 0.186 0.4127 1 0.30722 1 0.71982 1 0.014565 1 0.036449 1 0.36773 1 0.15393 1 12p gain 23 (9%) 221 4.4055e-07 0.000269 0.14692 1 0.88313 1 0.92836 1 0.0017199 0.991 0.20852 1 0.30561 1 0.45702 1 12q gain 11 (5%) 233 0.00069107 0.404 0.62881 1 0.84658 1 0.80659 1 0.059725 1 0.097092 1 0.56444 1 0.12402 1 13q gain 39 (16%) 205 7.0002e-06 0.00424 2.3002e-05 0.0138 0.39853 1 0.17425 1 0.0082774 1 0.014069 1 0.50247 1 0.3079 1 14q gain 16 (7%) 228 0.034793 1 0.061424 1 0.043079 1 0.2567 1 1 1 0.74844 1 0.79768 1 0.6765 1 15q gain 35 (14%) 209 1.9991e-06 0.00122 0.41977 1 0.56665 1 0.91224 1 0.50374 1 0.49192 1 1 1 0.12342 1 16p gain 16 (7%) 228 0.00055354 0.325 0.009132 1 0.45191 1 0.7244 1 0.013166 1 0.28021 1 0.59188 1 0.62276 1 16q gain 15 (6%) 229 0.015371 1 0.046195 1 0.19217 1 0.52674 1 0.02221 1 0.36403 1 0.4777 1 0.34165 1 17p gain 16 (7%) 228 0.063618 1 0.20687 1 0.71856 1 0.79003 1 0.4638 1 0.38826 1 0.21273 1 0.3981 1 17q gain 28 (11%) 216 0.021379 1 0.044147 1 0.70178 1 0.29297 1 0.29845 1 0.2084 1 0.10798 1 0.78437 1 18p gain 27 (11%) 217 0.051139 1 0.16055 1 0.90985 1 0.80089 1 0.067558 1 0.18121 1 0.093474 1 0.21122 1 18q gain 16 (7%) 228 0.034793 1 0.21921 1 0.53556 1 0.30764 1 0.27632 1 0.079526 1 0.94043 1 0.78744 1 19p gain 16 (7%) 228 0.0081165 1 0.028035 1 0.62295 1 0.20364 1 0.0050192 1 0.027242 1 0.16453 1 0.92982 1 19q gain 20 (8%) 224 0.0076074 1 0.039644 1 0.41539 1 0.6776 1 0.00068291 0.4 0.070401 1 0.65052 1 0.73484 1 20p gain 70 (29%) 174 6.076e-06 0.00369 0.0019492 1 0.34505 1 0.90363 1 0.00014894 0.0891 0.0088747 1 0.079493 1 0.26876 1 20q gain 89 (36%) 155 1.6575e-08 1.02e-05 0.0019876 1 0.44788 1 0.80222 1 0.00077071 0.449 0.058451 1 0.35103 1 0.5121 1 21q gain 29 (12%) 215 0.038424 1 0.00026081 0.155 0.18161 1 0.40155 1 0.10605 1 0.055284 1 0.53814 1 1 1 22q gain 59 (24%) 185 0.0020942 1 0.19746 1 0.80323 1 0.93285 1 0.32407 1 0.81142 1 0.60119 1 0.46918 1 Xq gain 4 (2%) 240 0.82894 1 0.8353 1 1 1 0.50711 1 0.20716 1 0.089739 1 0.53504 1 0.57653 1 1p loss 15 (6%) 229 0.060475 1 0.025611 1 0.38276 1 0.41634 1 0.014209 1 0.10122 1 0.83296 1 0.78744 1 1q loss 7 (3%) 237 0.063679 1 0.34458 1 0.5445 1 0.56303 1 0.18207 1 0.60249 1 0.61233 1 1 1 2p loss 18 (7%) 226 0.0088328 1 0.1057 1 0.30574 1 0.038365 1 0.69519 1 0.077127 1 0.0004823 0.284 0.0059174 1 2q loss 19 (8%) 225 0.022495 1 0.01715 1 0.20779 1 0.14965 1 0.34087 1 0.078433 1 0.00085164 0.494 0.027986 1 3p loss 22 (9%) 222 0.058538 1 0.076118 1 0.38163 1 0.36403 1 0.0040479 1 0.031001 1 0.87683 1 0.27023 1 3q loss 19 (8%) 225 0.073473 1 0.060552 1 0.42121 1 0.20933 1 0.10527 1 0.25218 1 0.863 1 0.21416 1 4p loss 30 (12%) 214 0.32186 1 0.1933 1 0.34168 1 0.13245 1 0.0079875 1 0.0088585 1 0.79282 1 0.1789 1 4q loss 31 (13%) 213 0.14155 1 0.066384 1 0.30806 1 0.02057 1 0.0097391 1 0.0028079 1 0.39092 1 0.045319 1 5p loss 32 (13%) 212 0.70134 1 0.26232 1 0.27238 1 0.33303 1 0.33057 1 0.14236 1 0.062426 1 0.26012 1 5q loss 46 (19%) 198 0.51477 1 0.043646 1 0.068857 1 0.55318 1 0.27254 1 0.25117 1 0.63721 1 0.66317 1 6p loss 28 (11%) 216 0.0085675 1 0.21544 1 0.4665 1 0.34726 1 0.35524 1 0.23223 1 0.33201 1 0.21323 1 6q loss 90 (37%) 154 0.0001109 0.0664 0.00070463 0.411 0.35417 1 0.45416 1 0.0041618 1 0.015958 1 0.53464 1 0.25699 1 7p loss 7 (3%) 237 0.79857 1 0.034783 1 0.6645 1 0.47064 1 0.79542 1 1 1 0.41949 1 1 1 7q loss 6 (2%) 238 0.676 1 0.091108 1 0.77926 1 0.70257 1 1 1 0.87817 1 1 1 0.83903 1 8p loss 28 (11%) 216 0.067891 1 0.11105 1 0.05702 1 0.4862 1 0.052526 1 0.20066 1 0.080375 1 0.12424 1 8q loss 5 (2%) 239 1 1 0.07052 1 0.13857 1 0.51542 1 0.326 1 0.03845 1 0.84365 1 0.79769 1 9p loss 134 (55%) 110 3.3095e-08 2.03e-05 1.9293e-05 0.0117 0.18758 1 0.13065 1 0.0029192 1 0.0029718 1 1 1 0.4069 1 9q loss 100 (41%) 144 0.0056598 1 0.00044053 0.26 0.44783 1 0.36355 1 0.23775 1 0.89541 1 0.49633 1 0.63614 1 10p loss 103 (42%) 141 2.1931e-07 0.000134 5.5327e-05 0.0333 0.4398 1 0.15768 1 1.1268e-06 0.000686 0.0008637 0.5 0.57614 1 0.16343 1 10q loss 112 (46%) 132 3.0176e-10 1.87e-07 9.7807e-05 0.0587 0.53898 1 0.19182 1 1.1062e-06 0.000675 0.00066066 0.387 0.98494 1 0.376 1 11p loss 57 (23%) 187 0.0021874 1 0.0018017 1 0.48381 1 0.26981 1 0.055087 1 0.0063412 1 0.12025 1 0.66482 1 11q loss 64 (26%) 180 0.00038169 0.226 0.024619 1 0.91636 1 0.76364 1 0.0502 1 0.0013593 0.784 0.60915 1 0.46776 1 12p loss 15 (6%) 229 0.16712 1 0.0088094 1 0.50038 1 0.81364 1 0.25943 1 0.29831 1 0.87953 1 0.7039 1 12q loss 24 (10%) 220 0.0053754 1 0.0023858 1 0.83898 1 0.8748 1 0.32909 1 0.24096 1 0.77787 1 0.84797 1 13q loss 36 (15%) 208 0.32194 1 0.45389 1 0.17234 1 0.65644 1 0.66158 1 0.97097 1 0.082695 1 0.22373 1 14q loss 54 (22%) 190 6.9208e-08 4.24e-05 0.050793 1 0.41145 1 0.27586 1 0.004304 1 0.13386 1 1 1 0.43207 1 15q loss 15 (6%) 229 0.0002698 0.161 0.08491 1 0.6509 1 0.13763 1 0.6339 1 0.61053 1 0.26696 1 0.14857 1 16p loss 22 (9%) 222 0.02156 1 0.0056679 1 0.95625 1 0.2043 1 0.19926 1 0.26929 1 0.042029 1 0.50978 1 16q loss 46 (19%) 198 0.0058317 1 0.02925 1 0.57131 1 0.37339 1 0.054456 1 0.28605 1 0.040682 1 0.096079 1 17p loss 50 (20%) 194 0.61872 1 0.17506 1 0.4931 1 0.68797 1 0.067269 1 0.9546 1 0.64569 1 0.38799 1 17q loss 22 (9%) 222 0.080492 1 0.5136 1 0.38701 1 0.47028 1 0.12273 1 0.35699 1 0.49305 1 1 1 18p loss 48 (20%) 196 0.0038535 1 0.0043616 1 0.37245 1 0.41519 1 0.00028798 0.171 0.029072 1 0.93245 1 0.88545 1 18q loss 44 (18%) 200 0.012846 1 0.018225 1 0.050228 1 0.18768 1 0.05183 1 0.22137 1 0.86327 1 0.61631 1 19p loss 19 (8%) 225 0.21033 1 0.53995 1 0.0057819 1 0.53606 1 0.14237 1 0.36666 1 0.47249 1 0.93551 1 19q loss 19 (8%) 225 0.21997 1 0.36584 1 0.65383 1 0.3467 1 0.39526 1 0.94991 1 0.70687 1 0.93551 1 20p loss 12 (5%) 232 0.5281 1 0.42244 1 0.15262 1 0.74441 1 0.7551 1 0.22203 1 0.18359 1 0.55235 1 20q loss 3 (1%) 241 0.50252 1 0.18669 1 NA NA NA NA 0.50817 1 0.2135 1 1 1 1 1 21q loss 28 (11%) 216 0.26105 1 0.26523 1 0.823 1 0.63417 1 0.43571 1 0.45139 1 0.80946 1 0.30461 1 22q loss 19 (8%) 225 0.49801 1 0.20517 1 0.59089 1 0.42806 1 0.6444 1 0.42789 1 0.20791 1 0.80598 1 Xq loss 10 (4%) 234 0.27658 1 0.0032853 1 0.28298 1 0.18795 1 0.39585 1 0.081892 1 0.40427 1 0.63117 1